| GO term | GO name | GO namespace | GO def |
| GO:0032879 | regulation of localization | biological_process | Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. [GOC:mah] |
| GO:0048522 | positive regulation of cellular process | biological_process | Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid] |
| GO:0007166 | cell surface receptor signaling pathway | biological_process | A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:mah, GOC:pr, GOC:signaling] |
| GO:0042098 | T cell proliferation | biological_process | The expansion of a T cell population by cell division. Follows T cell activation. [GOC:jl] |
| GO:0098609 | cell-cell adhesion | biological_process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |
| GO:0044093 | positive regulation of molecular function | biological_process | Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. [GO:jl] |
| GO:0022407 | regulation of cell-cell adhesion | biological_process | Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. [GOC:isa_complete] |
| GO:0010629 | negative regulation of gene expression | biological_process | Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:1903706 | regulation of hemopoiesis | biological_process | Any process that modulates the frequency, rate or extent of hemopoiesis. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] |
| GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway | biological_process | Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway. [GOC:mtg_apoptosis] |
| GO:0032102 | negative regulation of response to external stimulus | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. [GOC:mah] |
| GO:0042110 | T cell activation | biological_process | The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [GOC:mgi_curators, ISBN:0781735149] |
| GO:0048523 | negative regulation of cellular process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid] |
| GO:0010468 | regulation of gene expression | biological_process | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0051050 | positive regulation of transport | biological_process | Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai] |
| GO:0006469 | negative regulation of protein kinase activity | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. [GOC:go_curators] |
| GO:0043666 | regulation of phosphoprotein phosphatase activity | biological_process | Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein. [GOC:jp, PMID:11724821] |
| GO:0048856 | anatomical structure development | biological_process | The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [GO_REF:0000021] |
| GO:0042995 | cell projection | cellular_component | A prolongation or process extending from a cell, e.g. a flagellum or axon. [GOC:jl, http://www.cogsci.princeton.edu/~wn/] |
| GO:0010605 | negative regulation of macromolecule metabolic process | biological_process | Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0010647 | positive regulation of cell communication | biological_process | Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:dph, GOC:tb] |
| GO:0016021 | integral component of membrane | cellular_component | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0001932 | regulation of protein phosphorylation | biological_process | Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. [GOC:hjd] |
| GO:0002683 | negative regulation of immune system process | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. [GOC:add] |
| GO:0009898 | cytoplasmic side of plasma membrane | cellular_component | The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb] |
| GO:0032502 | developmental process | biological_process | A biological process whose specific outcome is the progression of an integrated living unit |
| GO:0030334 | regulation of cell migration | biological_process | Any process that modulates the frequency, rate or extent of cell migration. [GOC:go_curators] |
| GO:0032270 | positive regulation of cellular protein metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. [GOC:mah] |
| GO:0050865 | regulation of cell activation | biological_process | Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. [GOC:ai] |
| GO:0050670 | regulation of lymphocyte proliferation | biological_process | Any process that modulates the frequency, rate or extent of lymphocyte proliferation. [GOC:ai] |
| GO:0031323 | regulation of cellular metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. [GOC:mah] |
| GO:0120025 | plasma membrane bounded cell projection | cellular_component | A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. [GOC:krc] |
| GO:0044770 | cell cycle phase transition | biological_process | The cell cycle process by which a cell commits to entering the next cell cycle phase. [GOC:mtg_cell_cycle] |
| GO:0008284 | positive regulation of cell population proliferation | biological_process | Any process that activates or increases the rate or extent of cell proliferation. [GOC:go_curators] |
| GO:0010604 | positive regulation of macromolecule metabolic process | biological_process | Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0038023 | signaling receptor activity | molecular_function | Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. [GOC:bf, GOC:signaling] |
| GO:0051246 | regulation of protein metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. [GOC:ai] |
| GO:0080090 | regulation of primary metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. [PMID:19211694] |
| GO:0019901 | protein kinase binding | molecular_function | Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. [GOC:jl] |
| GO:0035335 | peptidyl-tyrosine dephosphorylation | biological_process | The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. [GOC:bf] |
| GO:0050790 | regulation of catalytic activity | biological_process | Any process that modulates the activity of an enzyme. [GOC:ai, GOC:ebc, GOC:vw] |
| GO:0051272 | positive regulation of cellular component movement | biological_process | Any process that activates or increases the frequency, rate or extent of the movement of a cellular component. [GOC:ai, GOC:dph, GOC:jl] |
| GO:0051179 | localization | biological_process | Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. [GOC:ai, GOC:dos] |
| GO:0007155 | cell adhesion | biological_process | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf] |
| GO:0030098 | lymphocyte differentiation | biological_process | The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. [CL:0000542, GOC:go_curators] |
| GO:0009966 | regulation of signal transduction | biological_process | Any process that modulates the frequency, rate or extent of signal transduction. [GOC:sm] |
| GO:0048468 | cell development | biological_process | The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. [GOC:go_curators] |
| GO:0045860 | positive regulation of protein kinase activity | biological_process | Any process that activates or increases the frequency, rate or extent of protein kinase activity. [GOC:go_curators] |
| GO:0048869 | cellular developmental process | biological_process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. [GOC:isa_complete] |
| GO:0040012 | regulation of locomotion | biological_process | Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. [GOC:ems] |
| GO:0048519 | negative regulation of biological process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid] |
| GO:0035303 | regulation of dephosphorylation | biological_process | Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf] |
| GO:0048585 | negative regulation of response to stimulus | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid] |
| GO:0032268 | regulation of cellular protein metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. [GOC:mah] |
| GO:0002696 | positive regulation of leukocyte activation | biological_process | Any process that activates or increases the frequency, rate, or extent of leukocyte activation. [GOC:add] |
| GO:0050867 | positive regulation of cell activation | biological_process | Any process that activates or increases the frequency, rate or extent of activation. [GOC:ai] |
| GO:0050852 | T cell receptor signaling pathway | biological_process | A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. [GOC:add] |
| GO:0048584 | positive regulation of response to stimulus | biological_process | Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid] |
| GO:0061024 | membrane organization | biological_process | A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. [GOC:dph, GOC:tb] |
| GO:0031324 | negative regulation of cellular metabolic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. [GOC:mah] |
| GO:0009314 | response to radiation | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. [GOC:jl, Wikipedia:Electromagnetic_radiation] |
| GO:0035556 | intracellular signal transduction | biological_process | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] |
| GO:0044877 | protein-containing complex binding | molecular_function | Binding to a macromolecular complex. [GOC:jl] |
| GO:0019722 | calcium-mediated signaling | biological_process | Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. [GOC:signaling] |
| GO:0016043 | cellular component organization | biological_process | A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:ai, GOC:jl, GOC:mah] |
| GO:0030155 | regulation of cell adhesion | biological_process | Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. [GOC:mah] |
| GO:0030183 | B cell differentiation | biological_process | The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. [GO_REF:0000022, GOC:mah] |
| GO:0031982 | vesicle | cellular_component | Any small, fluid-filled, spherical organelle enclosed by membrane. [GOC:mah, GOC:pz, GOC:vesicles] |
| GO:0002699 | positive regulation of immune effector process | biological_process | Any process that activates or increases the frequency, rate, or extent of an immune effector process. [GOC:add] |
| GO:0051348 | negative regulation of transferase activity | biological_process | Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. [GOC:ai] |
| GO:2000145 | regulation of cell motility | biological_process | Any process that modulates the frequency, rate or extent of cell motility. [GOC:mah] |
| GO:0043410 | positive regulation of MAPK cascade | biological_process | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. [GOC:go_curators] |
| GO:0010648 | negative regulation of cell communication | biological_process | Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:dph, GOC:tb] |
| GO:0002700 | regulation of production of molecular mediator of immune response | biological_process | Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. [GOC:add] |
| GO:0051209 | release of sequestered calcium ion into cytosol | biological_process | The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment. [GOC:dph, GOC:hjd, GOC:mtg_lung, PMID:1814929] |
| GO:0042102 | positive regulation of T cell proliferation | biological_process | Any process that activates or increases the rate or extent of T cell proliferation. [GOC:ai] |
| GO:0031400 | negative regulation of protein modification process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. [GOC:mah, GOC:tb] |
| GO:0043227 | membrane-bounded organelle | cellular_component | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators] |
| GO:0035304 | regulation of protein dephosphorylation | biological_process | Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein. [GOC:bf] |
| GO:0009628 | response to abiotic stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. [GOC:hb] |
| GO:0030667 | secretory granule membrane | cellular_component | The lipid bilayer surrounding a secretory granule. [GOC:mah] |
| GO:0043409 | negative regulation of MAPK cascade | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. [GOC:go_curators] |
| GO:0005887 | integral component of plasma membrane | cellular_component | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators] |
| GO:0031325 | positive regulation of cellular metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. [GOC:mah] |
| GO:0051241 | negative regulation of multicellular organismal process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai] |
| GO:0023056 | positive regulation of signaling | biological_process | Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. [GOC:mtg_signal] |
| GO:0051094 | positive regulation of developmental process | biological_process | Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:ai] |
| GO:0016787 | hydrolase activity | molecular_function | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [ISBN:0198506732] |
| GO:0002697 | regulation of immune effector process | biological_process | Any process that modulates the frequency, rate, or extent of an immune effector process. [GOC:add] |
| GO:0007165 | signal transduction | biological_process | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. [GOC:go_curators, GOC:mtg_signaling_feb11] |
| GO:0051249 | regulation of lymphocyte activation | biological_process | Any process that modulates the frequency, rate or extent of lymphocyte activation. [GOC:ai] |
| GO:0051251 | positive regulation of lymphocyte activation | biological_process | Any process that activates or increases the frequency, rate or extent of lymphocyte activation. [GOC:ai] |
| GO:0030888 | regulation of B cell proliferation | biological_process | Any process that modulates the frequency, rate or extent of B cell proliferation. [GOC:mah] |
| GO:0010563 | negative regulation of phosphorus metabolic process | biological_process | Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. [GOC:dph, GOC:tb] |
| GO:0040017 | positive regulation of locomotion | biological_process | Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. [GOC:go_curators] |
| GO:0051049 | regulation of transport | biological_process | Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai] |
| GO:0050776 | regulation of immune response | biological_process | Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai] |
| GO:2000026 | regulation of multicellular organismal development | biological_process | Any process that modulates the frequency, rate or extent of multicellular organismal development. [GOC:obol] |
| GO:0004721 | phosphoprotein phosphatase activity | molecular_function | Catalysis of the reaction |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. [GOC:ai, GOC:tb] |
| GO:0005925 | focal adhesion | cellular_component | A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). [GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002] |
| GO:0046649 | lymphocyte activation | biological_process | A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149] |
| GO:0009888 | tissue development | biological_process | The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. [ISBN:0471245208] |
| GO:0001817 | regulation of cytokine production | biological_process | Any process that modulates the frequency, rate, or extent of production of a cytokine. [GOC:add, ISBN:0781735149] |
| GO:0110165 | cellular anatomical entity | cellular_component | A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. [GOC:kmv] |
| GO:0050863 | regulation of T cell activation | biological_process | Any process that modulates the frequency, rate or extent of T cell activation. [GOC:ai] |
| GO:0060089 | molecular transducer activity | molecular_function | A compound molecular function in which an effector function is controlled by one or more regulatory components. [GOC:dos, GOC:pdt] |
| GO:0051174 | regulation of phosphorus metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. [GOC:ai] |
| GO:0042326 | negative regulation of phosphorylation | biological_process | Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. [GOC:jl] |
| GO:0050870 | positive regulation of T cell activation | biological_process | Any process that activates or increases the frequency, rate or extent of T cell activation. [GOC:ai] |
| GO:0065009 | regulation of molecular function | biological_process | Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. [GOC:isa_complete] |
| GO:0002694 | regulation of leukocyte activation | biological_process | Any process that modulates the frequency, rate, or extent of leukocyte activation. [GOC:add] |
| GO:0002891 | positive regulation of immunoglobulin mediated immune response | biological_process | Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. [GOC:add] |
| GO:0065007 | biological regulation | biological_process | Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | biological_process | Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] |
| GO:0051270 | regulation of cellular component movement | biological_process | Any process that modulates the frequency, rate or extent of the movement of a cellular component. [GOC:ai, GOC:dph, GOC:jl] |
| GO:0009986 | cell surface | cellular_component | The external part of the cell wall and/or plasma membrane. [GOC:jl, GOC:mtg_sensu, GOC:sm] |
| GO:0009968 | negative regulation of signal transduction | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. [GOC:sm] |
| GO:0051239 | regulation of multicellular organismal process | biological_process | Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai, GOC:dph, GOC:tb] |
| GO:0009987 | cellular process | biological_process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete] |
| GO:0042578 | phosphoric ester hydrolase activity | molecular_function | Catalysis of the reaction |
| GO:0030154 | cell differentiation | biological_process | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [ISBN:0198506732] |
| GO:0140096 | catalytic activity, acting on a protein | molecular_function | Catalytic activity that acts to modify a protein. [GOC:molecular_function_refactoring, GOC:pdt] |
| GO:0002706 | regulation of lymphocyte mediated immunity | biological_process | Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. [GOC:add] |
| GO:0045595 | regulation of cell differentiation | biological_process | Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. [GOC:go_curators] |
| GO:0042127 | regulation of cell population proliferation | biological_process | Any process that modulates the frequency, rate or extent of cell proliferation. [GOC:jl] |
| GO:0051248 | negative regulation of protein metabolic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. [GOC:ai] |
| GO:0002695 | negative regulation of leukocyte activation | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. [GOC:add] |
| GO:0016311 | dephosphorylation | biological_process | The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. [ISBN:0198506732] |
| GO:0031401 | positive regulation of protein modification process | biological_process | Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. [GOC:mah, GOC:tb] |
| GO:0023057 | negative regulation of signaling | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. [GOC:mtg_signal] |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | biological_process | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. [GOC:mah] |
| GO:0010562 | positive regulation of phosphorus metabolic process | biological_process | Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. [GOC:dph, GOC:tb] |
| GO:0006470 | protein dephosphorylation | biological_process | The process of removing one or more phosphoric residues from a protein. [GOC:hb] |
| GO:0007162 | negative regulation of cell adhesion | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. [GOC:go_curators] |
| GO:0043408 | regulation of MAPK cascade | biological_process | Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade. [GOC:go_curators] |
| GO:0033673 | negative regulation of kinase activity | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [GOC:mah] |
| GO:0032944 | regulation of mononuclear cell proliferation | biological_process | Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. [GOC:add] |
| GO:0050896 | response to stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. [GOC:ai, GOC:bf] |
| GO:0002521 | leukocyte differentiation | biological_process | The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. [CL:0000738, GOC:add, PMID:16551264] |
| GO:0002682 | regulation of immune system process | biological_process | Any process that modulates the frequency, rate, or extent of an immune system process. [GOC:add] |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. [GOC:ai, GOC:tb] |
| GO:0002821 | positive regulation of adaptive immune response | biological_process | Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. [GOC:add] |
| GO:0002703 | regulation of leukocyte mediated immunity | biological_process | Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. [GOC:add] |
| GO:0000018 | regulation of DNA recombination | biological_process | Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. [GOC:go_curators, ISBN:0198506732] |
| GO:0050728 | negative regulation of inflammatory response | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. [GOC:ai] |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | biological_process | Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] |
| GO:0001933 | negative regulation of protein phosphorylation | biological_process | Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. [GOC:hjd] |
| GO:0004888 | transmembrane signaling receptor activity | molecular_function | Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. [GOC:go_curators, Wikipedia:Transmembrane_receptor] |
| GO:0045937 | positive regulation of phosphate metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. [GOC:go_curators] |
| GO:0007159 | leukocyte cell-cell adhesion | biological_process | The attachment of a leukocyte to another cell via adhesion molecules. [GOC:go_curators] |
| GO:0044092 | negative regulation of molecular function | biological_process | Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. [GO:jl] |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai] |
| GO:0050778 | positive regulation of immune response | biological_process | Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai] |
| GO:0004725 | protein tyrosine phosphatase activity | molecular_function | Catalysis of the reaction |
| GO:0048513 | animal organ development | biological_process | Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:dph, GOC:jid] |
| GO:0019220 | regulation of phosphate metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. [GOC:go_curators] |
| GO:0043086 | negative regulation of catalytic activity | biological_process | Any process that stops or reduces the activity of an enzyme. [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] |
| GO:0016788 | hydrolase activity, acting on ester bonds | molecular_function | Catalysis of the hydrolysis of any ester bond. [GOC:jl] |
| GO:0051726 | regulation of cell cycle | biological_process | Any process that modulates the rate or extent of progression through the cell cycle. [GOC:ai, GOC:dph, GOC:tb] |
| GO:0009893 | positive regulation of metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. [GOC:go_curators] |
| GO:0060255 | regulation of macromolecule metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0005488 | binding | molecular_function | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732] |
| GO:0043085 | positive regulation of catalytic activity | biological_process | Any process that activates or increases the activity of an enzyme. [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] |
| GO:0010921 | regulation of phosphatase activity | biological_process | Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0045785 | positive regulation of cell adhesion | biological_process | Any process that activates or increases the frequency, rate or extent of cell adhesion. [GOC:go_curators] |
| GO:0048583 | regulation of response to stimulus | biological_process | Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid] |
| GO:0030217 | T cell differentiation | biological_process | The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. [GO_REF:0000022, GOC:jid, GOC:mah] |
| GO:0032269 | negative regulation of cellular protein metabolic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. [GOC:mah] |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | biological_process | Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai] |
| GO:0050727 | regulation of inflammatory response | biological_process | Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. [GOC:ai] |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | biological_process | Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:go_curators] |
| GO:0051052 | regulation of DNA metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. [GOC:ai] |
| GO:0002708 | positive regulation of lymphocyte mediated immunity | biological_process | Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. [GOC:add] |
| GO:0048534 | hematopoietic or lymphoid organ development | biological_process | The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. [GOC:add, GOC:rl, ISBN:0781735149] |
| GO:0048518 | positive regulation of biological process | biological_process | Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid] |
| GO:0042129 | regulation of T cell proliferation | biological_process | Any process that modulates the frequency, rate or extent of T cell proliferation. [GOC:jl] |
| GO:0045936 | negative regulation of phosphate metabolic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. [GOC:go_curators] |
| GO:0050793 | regulation of developmental process | biological_process | Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:go_curators] |
| GO:0003824 | catalytic activity | molecular_function | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732] |
| GO:0001819 | positive regulation of cytokine production | biological_process | Any process that activates or increases the frequency, rate or extent of production of a cytokine. [GOC:add, ISBN:0781735149] |
| GO:0016791 | phosphatase activity | molecular_function | Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. [GOC:curators, GOC:pg] |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | biological_process | Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:go_curators] |
| GO:0010646 | regulation of cell communication | biological_process | Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:dph, GOC:tb] |
| GO:0045121 | membrane raft | cellular_component | Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. [PMID:16645198, PMID:20044567] |
| GO:0031668 | cellular response to extracellular stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. [GOC:mah] |
| GO:0046425 | regulation of receptor signaling pathway via JAK-STAT | biological_process | Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT. [GOC:bf] |
| GO:0023051 | regulation of signaling | biological_process | Any process that modulates the frequency, rate or extent of a signaling process. [GOC:mtg_signal] |
| GO:0060627 | regulation of vesicle-mediated transport | biological_process | Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. [GOC:dph, GOC:tb] |
| GO:0051641 | cellular localization | biological_process | A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. [GOC:tb, GOC:vw] |
| GO:0045597 | positive regulation of cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of cell differentiation. [GOC:go_curators] |
| GO:0030335 | positive regulation of cell migration | biological_process | Any process that activates or increases the frequency, rate or extent of cell migration. [GOC:go_curators] |
| GO:0010212 | response to ionizing radiation | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. [PMID:12509526] |
| GO:0098857 | membrane microdomain | cellular_component | A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it. [PMID:20044567, PMID:26253820] |
| GO:0071840 | cellular component organization or biogenesis | biological_process | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:mah] |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | biological_process | Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. [GOC:add, ISBN:0121245462, ISBN:0896039986] |
| GO:0022409 | positive regulation of cell-cell adhesion | biological_process | Any process that activates or increases the rate or extent of cell adhesion to another cell. [GOC:isa_complete] |
| GO:0051336 | regulation of hydrolase activity | biological_process | Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [GOC:ai] |
| GO:0002705 | positive regulation of leukocyte mediated immunity | biological_process | Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. [GOC:add] |
| GO:0043226 | organelle | cellular_component | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. [GOC:go_curators] |
| GO:0022610 | biological adhesion | biological_process | The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions. [GOC:isa_complete] |
| GO:0050789 | regulation of biological process | biological_process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators] |
| GO:0001775 | cell activation | biological_process | A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. [GOC:mgi_curators] |
| GO:0045321 | leukocyte activation | biological_process | A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. [GOC:add] |
| GO:0050853 | B cell receptor signaling pathway | biological_process | A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell. [GOC:add] |
| GO:0008201 | heparin binding | molecular_function | Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. [GOC:jl, ISBN:0198506732] |
| GO:0002684 | positive regulation of immune system process | biological_process | Any process that activates or increases the frequency, rate, or extent of an immune system process. [GOC:add] |
| GO:0050794 | regulation of cellular process | biological_process | Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators] |
| GO:0045582 | positive regulation of T cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of T cell differentiation. [GOC:go_curators] |
| GO:0050866 | negative regulation of cell activation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. [GOC:ai] |
| GO:0007009 | plasma membrane organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. [GOC:dph, GOC:jl, GOC:mah] |
| GO:0032101 | regulation of response to external stimulus | biological_process | Any process that modulates the frequency, rate or extent of a response to an external stimulus. [GOC:mah] |
| GO:1902532 | negative regulation of intracellular signal transduction | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] |
| GO:0019932 | second-messenger-mediated signaling | biological_process | Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell. [GOC:signaling, ISBN:0815316194, PMID:15221855, Wikipedia:Second_messenger_system] |
| GO:0070663 | regulation of leukocyte proliferation | biological_process | Any process that modulates the frequency, rate or extent of leukocyte proliferation. [GOC:add, GOC:mah] |
| GO:0051607 | defense response to virus | biological_process | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. [GOC:ai] |
| GO:0045859 | regulation of protein kinase activity | biological_process | Any process that modulates the frequency, rate or extent of protein kinase activity. [GOC:go_curators] |
| GO:0051345 | positive regulation of hydrolase activity | biological_process | Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. [GOC:ai] |
| GO:0080134 | regulation of response to stress | biological_process | Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:dhl] |
| GO:0002376 | immune system process | biological_process | Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. [GO_REF:0000022, GOC:add] |
| GO:0009967 | positive regulation of signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of signal transduction. [GOC:sm] |
| GO:0051240 | positive regulation of multicellular organismal process | biological_process | Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai] |
| GO:0051338 | regulation of transferase activity | biological_process | Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. [GOC:ai] |
| GO:0051171 | regulation of nitrogen compound metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. [GOC:ai, GOC:tb] |
| GO:0002819 | regulation of adaptive immune response | biological_process | Any process that modulates the frequency, rate, or extent of an adaptive immune response. [GOC:add] |
| GO:0042325 | regulation of phosphorylation | biological_process | Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. [GOC:jl] |
| GO:0031399 | regulation of protein modification process | biological_process | Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. [GOC:mah, GOC:tb] |
| GO:0043406 | positive regulation of MAP kinase activity | biological_process | Any process that activates or increases the frequency, rate or extent of MAP kinase activity. [GOC:dph, GOC:go_curators] |
| GO:0010628 | positive regulation of gene expression | biological_process | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0009892 | negative regulation of metabolic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. [GOC:go_curators] |
| GO:2000147 | positive regulation of cell motility | biological_process | Any process that activates or increases the frequency, rate or extent of cell motility. [GOC:mah] |
| GO:0008092 | cytoskeletal protein binding | molecular_function | Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). [GOC:mah] |
| GO:0042100 | B cell proliferation | biological_process | The expansion of a B cell population by cell division. Follows B cell activation. [GOC:jl] |
| GO:1902531 | regulation of intracellular signal transduction | biological_process | Any process that modulates the frequency, rate or extent of intracellular signal transduction. [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] |
| GO:0002639 | positive regulation of immunoglobulin production | biological_process | Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. [GOC:add] |
| GO:0031347 | regulation of defense response | biological_process | Any process that modulates the frequency, rate or extent of a defense response. [GOC:mah] |
| GO:0097367 | carbohydrate derivative binding | molecular_function | Binding to a carbohydrate derivative. [GOC:pr] |
| GO:0043549 | regulation of kinase activity | biological_process | Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [GOC:bf] |
| GO:0051247 | positive regulation of protein metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. [GOC:ai] |
| GO:0009897 | external side of plasma membrane | cellular_component | The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0019222 | regulation of metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. [GOC:go_curators] |
| GO:0005102 | signaling receptor binding | molecular_function | Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:bf, GOC:ceb, ISBN:0198506732] |