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Total number of protein in "GO:0048534" GO term:  121

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0048534 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADA ADA P00813 Adenosine deaminase chr20 GO:0048534 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0048534 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0048534 Not Cancer Driver No 149 0.122 675 83 0.123 12
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0048534 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0048534 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0048534 Census, Compendium Yes 469 0.153 225 39 0.173 41
BARX1 BARX1 Q9HBU1 Homeobox protein BarH-like 1 chr9 GO:0048534 Not Cancer Driver No 12 0.047 165 9 0.055 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0048534 Census, Compendium Yes 156 0.174 699 114 0.163 2
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0048534 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0048534 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0048534 Census Yes 44 0.097 259 23 0.089 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0048534 Census, Compendium Yes 146 0.115 603 69 0.114 0
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0048534 Not Cancer Driver No 17 0.12 34 6 0.176 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0048534 Census, Compendium Yes 39 0.214 94 17 0.181 0
CCDC134 CCDC134 Q9H6E4 Coiled-coil domain-containing protein 134 chr22 GO:0048534 Not Cancer Driver No 24 0.105 43 3 0.07 0
CCNB2 CCNB2 O95067 G2/mitotic-specific cyclin-B2 chr15 GO:0048534 Not Cancer Driver No 33 0.083 103 10 0.097 0
CD248 CD248 Q9HCU0 Endosialin chr11 GO:0048534 Not Cancer Driver No 110 0.145 369 58 0.157 0
CDH17 CDH17 Q12864 Cadherin-17 chr8 GO:0048534 Census Yes 166 0.2 186 35 0.188 0
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0048534 Not Cancer Driver No 15 0.109 67 3 0.045 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0048534 Not Cancer Driver No 23 0.085 230 18 0.078 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0048534 Not Cancer Driver No 38 0.125 160 25 0.156 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0048534 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0048534 Census, Compendium Yes 415 0.531 288 301 1.045 14
CXCR5 CXCR5 P32302 C-X-C chemokine receptor type 5 chr11 GO:0048534 Not Cancer Driver No 41 0.11 0 0 0.0 0
EPB42_ENST00000441366 EPB42 P16452 Protein 4.2 chr15 GO:0048534 Not Cancer Driver No 94 0.136 113 10 0.088 4
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0048534 Not Cancer Driver No 155 0.155 137 16 0.117 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0048534 Not Cancer Driver No 42 0.141 105 14 0.133 1
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0048534 Not Cancer Driver No 26 0.125 45 10 0.222 1
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0048534 Not Cancer Driver No 56 0.269 34 11 0.324 2
FLT3LG_ENST00000600429 FLT3LG P49771 Fms-related tyrosine kinase 3 ligand chr19 GO:0048534 Not Cancer Driver No 27 0.115 39 4 0.103 0
FLVCR1 FLVCR1 Q9Y5Y0 Feline leukemia virus subgroup C receptor-related protein 1 chr1 GO:0048534 Not Cancer Driver No 58 0.105 117 14 0.12 4
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 GO:0048534 Not Cancer Driver No 38 0.102 133 5 0.038 4
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0048534 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0048534 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0048534 Census, Compendium Yes 111 0.251 364 87 0.239 2
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0048534 Not Cancer Driver No 47 0.217 124 29 0.234 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0048534 Not Cancer Driver No 37 0.132 226 32 0.142 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0048534 Census Yes 118 0.143 435 51 0.117 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0048534 Not Cancer Driver No 158 0.131 565 89 0.158 0
HOXA3_ENST00000396352 HOXA3 O43365 Homeobox protein Hox-A3 chr7 GO:0048534 Not Cancer Driver No 86 0.194 417 84 0.201 0
HOXB3_ENST00000498678 HOXB3 P14651 Homeobox protein Hox-B3 chr17 GO:0048534 Not Cancer Driver No 74 0.172 398 66 0.166 0
HOXB4 HOXB4 P17483 Homeobox protein Hox-B4 chr17 GO:0048534 Not Cancer Driver No 41 0.163 210 33 0.157 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0048534 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL3 IL3 P08700 Interleukin-3 chr5 GO:0048534 Not Cancer Driver No 25 0.164 22 3 0.136 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0048534 Census, Compendium Yes 177 0.386 88 48 0.545 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0048534 Census, Compendium Yes 136 0.12 59 5 0.085 5
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0048534 Not Cancer Driver No 190 0.152 724 113 0.156 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0048534 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0048534 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0048534 Not Cancer Driver No 48 0.176 61 9 0.148 1
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0048534 Census, Compendium Yes 446 0.112 3145 338 0.107 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 GO:0048534 Not Cancer Driver No 30 0.182 11 1 0.091 0
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0048534 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP5L_ENST00000402785 LRP5L A4QPB2 Low-density lipoprotein receptor-related protein 5-like protein chr22 GO:0048534 Not Cancer Driver No 38 0.151 39 5 0.128 0
LRRC17 LRRC17 Q8N6Y2 Leucine-rich repeat-containing protein 17 chr7 GO:0048534 Not Cancer Driver No 58 0.132 88 11 0.125 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0048534 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTB LTB Q06643 Lymphotoxin-beta chr6 GO:0048534 Compendium Yes 33 0.135 91 13 0.143 0
LYL1 LYL1 P12980 Protein lyl-1 chr19 GO:0048534 Census Yes 15 0.054 243 11 0.045 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:0048534 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0048534 Census Yes 35 0.108 301 34 0.113 10
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0048534 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0048534 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0048534 Not Cancer Driver No 38 0.1 49 5 0.102 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0048534 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0048534 Not Cancer Driver No 89 0.228 267 62 0.232 0
MFAP5 MFAP5 Q13361 Microfibrillar-associated protein 5 chr12 GO:0048534 Not Cancer Driver No 51 0.295 30 10 0.333 1
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 GO:0048534 Not Cancer Driver No 137 0.124 229 14 0.061 1
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 GO:0048534 Census, Compendium Yes 86 0.096 510 46 0.09 0
NKX2-3 NKX2-3 Q8TAU0 Homeobox protein Nkx-2.3 chr10 GO:0048534 Not Cancer Driver No 31 0.085 212 27 0.127 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0048534 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX3-2 NKX3-2 P78367 Homeobox protein Nkx-3.2 chr4 GO:0048534 Not Cancer Driver No 36 0.108 212 27 0.127 0
ONECUT1 ONECUT1 Q9UBC0 Hepatocyte nuclear factor 6 chr15 GO:0048534 Not Cancer Driver No 78 0.168 405 65 0.16 0
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0048534 Census Yes 82 0.191 290 57 0.197 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0048534 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0048534 Not Cancer Driver No 37 0.228 96 24 0.25 0
PITX2_ENST00000354925 PITX2 Q99697 Pituitary homeobox 2 chr4 GO:0048534 Not Cancer Driver No 74 0.233 185 43 0.232 13
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0048534 Not Cancer Driver No 120 0.127 459 54 0.118 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0048534 Not Cancer Driver No 43 0.128 87 11 0.126 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0048534 Not Cancer Driver No 44 0.097 30 3 0.1 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0048534 Not Cancer Driver No 24 0.121 30 4 0.133 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0048534 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0048534 Census, Compendium Yes 315 0.241 462 107 0.232 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0048534 Census, Compendium Yes 89 0.137 169 38 0.225 22
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0048534 Not Cancer Driver No 204 0.196 208 43 0.207 36
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0048534 Census, Compendium Yes 118 0.121 686 91 0.133 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0048534 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0048534 Not Cancer Driver No 128 0.107 703 81 0.115 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0048534 Not Cancer Driver No 66 0.127 295 39 0.132 0
SBDS SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 GO:0048534 Census Yes 28 0.112 12 1 0.083 2
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0048534 Census, Compendium Yes 48 0.083 333 19 0.057 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0048534 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0048534 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0048534 Not Cancer Driver No 99 0.127 460 58 0.126 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0048534 Not Cancer Driver No 45 0.095 36 3 0.083 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0048534 Not Cancer Driver No 16 0.104 93 9 0.097 79
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0048534 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPNS2 SPNS2 Q8IVW8 Sphingosine-1-phosphate transporter SPNS2 chr17 GO:0048534 Not Cancer Driver No 54 0.098 82 0 0.0 0
SRF SRF P11831 Serum response factor chr6 GO:0048534 Not Cancer Driver No 44 0.087 443 42 0.095 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0048534 Census, Compendium Yes 93 0.118 144 19 0.132 5
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0048534 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0048534 Not Cancer Driver No 70 0.144 231 30 0.13 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0048534 Census Yes 54 0.163 305 53 0.174 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0048534 Not Cancer Driver No 35 0.088 197 12 0.061 4
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0048534 Not Cancer Driver No 55 0.307 120 40 0.333 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0048534 Not Cancer Driver No 219 0.195 126 22 0.175 10
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0048534 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0048534 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0048534 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0048534 Not Cancer Driver No 129 0.152 268 41 0.153 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:0048534 Not Cancer Driver No 88 0.129 173 25 0.145 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0048534 Not Cancer Driver No 70 0.114 285 33 0.116 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0048534 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0048534 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPO TPO P07202 Thyroid peroxidase chr2 GO:0048534 Not Cancer Driver No 326 0.349 163 69 0.423 24
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0048534 Not Cancer Driver No 59 0.103 410 39 0.095 2
TYR TYR P14679 Tyrosinase chr11 GO:0048534 Not Cancer Driver No 156 0.295 52 15 0.288 111
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0048534 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0048534 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:0048534 Not Cancer Driver No 50 0.05 772 27 0.035 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0048534 Not Cancer Driver No 67 0.141 23 0 0.0 3