Total number of protein in "GO:0002639" GO term: 52
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:0002639 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| C17orf99 | C17orf99 | Q6UX52 | Protein IL-40 | chr17 | GO:0002639 | Not Cancer Driver | No | 16 | 0.06 | 84 | 3 | 0.036 | 0 |
| CD28 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0002639 | Census | Yes | 42 | 0.191 | 18 | 10 | 0.556 | 0 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0002639 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| CD86 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:0002639 | Not Cancer Driver | No | 90 | 0.274 | 56 | 18 | 0.321 | 0 |
| CLCF1 | CLCF1 | Q9UBD9 | Cardiotrophin-like cytokine factor 1 | chr11 | GO:0002639 | Not Cancer Driver | No | 22 | 0.098 | 42 | 4 | 0.095 | 1 |
| DNAJB9 | DNAJB9 | Q9UBS3 | DnaJ homolog subfamily B member 9 | chr7 | GO:0002639 | Not Cancer Driver | No | 30 | 0.135 | 107 | 15 | 0.14 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0002639 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0002639 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | GO:0002639 | Not Cancer Driver | No | 3 | 0.011 | 102 | 0 | 0.0 | 0 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0002639 | Not Cancer Driver | No | 77 | 0.138 | 73 | 11 | 0.151 | 24 |
| HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | GO:0002639 | Not Cancer Driver | No | 63 | 0.176 | 138 | 39 | 0.283 | 0 |
| HMCES_ENST00000502878 | HMCES | Q96FZ2 | Abasic site processing protein HMCES | chr3 | GO:0002639 | Not Cancer Driver | No | 37 | 0.105 | 131 | 16 | 0.122 | 0 |
| HPX | HPX | P02790 | Hemopexin | chr11 | GO:0002639 | Not Cancer Driver | No | 60 | 0.13 | 53 | 8 | 0.151 | 0 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0002639 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| IL13 | IL13 | P35225 | Interleukin-13 | chr5 | GO:0002639 | Not Cancer Driver | No | 20 | 0.137 | 0 | 0 | 0.0 | 0 |
| IL2 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0002639 | Census | Yes | 24 | 0.157 | 6 | 1 | 0.167 | 0 |
| IL21 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0002639 | Not Cancer Driver | No | 34 | 0.21 | 70 | 18 | 0.257 | 1 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0002639 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| IL4R_ENST00000543915 | IL4R | P24394 | Interleukin-4 receptor subunit alpha | chr16 | GO:0002639 | Not Cancer Driver | No | 133 | 0.161 | 420 | 64 | 0.152 | 0 |
| IL5 | IL5 | P05113 | Interleukin-5 | chr5 | GO:0002639 | Not Cancer Driver | No | 13 | 0.097 | 0 | 0 | 0.0 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0002639 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| KMT5B_ENST00000615954 | KMT5B | Q4FZB7 | Histone-lysine N-methyltransferase KMT5B | chr11 | GO:0002639 | Not Cancer Driver | No | 147 | 0.166 | 659 | 113 | 0.171 | 0 |
| KMT5C | KMT5C | Q86Y97 | Histone-lysine N-methyltransferase KMT5C | chr19 | GO:0002639 | Not Cancer Driver | No | 37 | 0.08 | 142 | 9 | 0.063 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0002639 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0002639 | Census | Yes | 92 | 0.122 | 208 | 22 | 0.106 | 85 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0002639 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
| MZB1 | MZB1 | Q8WU39 | Marginal zone B- and B1-cell-specific protein | chr5 | GO:0002639 | Not Cancer Driver | No | 15 | 0.079 | 75 | 9 | 0.12 | 0 |
| NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | GO:0002639 | Census, Compendium | Yes | 191 | 0.14 | 552 | 76 | 0.138 | 0 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:0002639 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:0002639 | Not Cancer Driver | No | 31 | 0.104 | 26 | 4 | 0.154 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0002639 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0002639 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| RBP4 | RBP4 | P02753 | Retinol-binding protein 4 | chr10 | GO:0002639 | Not Cancer Driver | No | 30 | 0.149 | 8 | 1 | 0.125 | 4 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0002639 | Not Cancer Driver | No | 287 | 0.116 | 1355 | 164 | 0.121 | 0 |
| SASH3 | SASH3 | O75995 | SAM and SH3 domain-containing protein 3 | chrX | GO:0002639 | Not Cancer Driver | No | 59 | 0.155 | 327 | 49 | 0.15 | 0 |
| SHLD1 | SHLD1 | Q8IYI0 | Shieldin complex subunit 1 | chr20 | GO:0002639 | Not Cancer Driver | No | 30 | 0.146 | 116 | 20 | 0.172 | 0 |
| SHLD2_ENST00000298784 | SHLD2 | Q86V20 | Shieldin complex subunit 2 | chr10 | GO:0002639 | Not Cancer Driver | No | 84 | 0.101 | 157 | 14 | 0.089 | 0 |
| SHLD3 | SHLD3 | Q6ZNX1 | Shieldin complex subunit 3 | chr5 | GO:0002639 | Not Cancer Driver | No | 3 | 0.012 | 81 | 1 | 0.012 | 0 |
| STAT6_ENST00000543873 | STAT6 | P42226 | Signal transducer and activator of transcription 6 | chr12 | GO:0002639 | Census, Compendium | Yes | 106 | 0.125 | 325 | 44 | 0.135 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | GO:0002639 | Not Cancer Driver | No | 50 | 0.168 | 152 | 20 | 0.132 | 0 |
| TBX21 | TBX21 | Q9UL17 | T-box transcription factor TBX21 | chr17 | GO:0002639 | Not Cancer Driver | No | 70 | 0.131 | 348 | 50 | 0.144 | 0 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | GO:0002639 | Census | Yes | 89 | 0.117 | 80 | 6 | 0.075 | 1 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0002639 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0002639 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TNFRSF4 | TNFRSF4 | P43489 | Tumor necrosis factor receptor superfamily member 4 | chr1 | GO:0002639 | Not Cancer Driver | No | 30 | 0.108 | 94 | 14 | 0.149 | 1 |
| TNFSF13 | TNFSF13 | O75888 | Tumor necrosis factor ligand superfamily member 13 | chr17 | GO:0002639 | Not Cancer Driver | No | 14 | 0.056 | 109 | 6 | 0.055 | 0 |
| TNFSF4 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0002639 | Not Cancer Driver | No | 28 | 0.153 | 1 | 0 | 0.0 | 0 |
| TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0002639 | Not Cancer Driver | No | 227 | 0.115 | 1632 | 190 | 0.116 | 0 |
| VAMP3 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | GO:0002639 | Not Cancer Driver | No | 11 | 0.11 | 17 | 1 | 0.059 | 0 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0002639 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0002639 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |