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Total number of protein in "GO:0042129" GO term:  91

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0042129 Not Cancer Driver No 31 0.077 297 21 0.071 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0042129 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0042129 Not Cancer Driver No 25 0.071 58 3 0.052 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0042129 Not Cancer Driver No 86 0.211 142 26 0.183 5
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0042129 Not Cancer Driver No 92 0.176 24 2 0.083 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0042129 Census Yes 32 0.116 62 5 0.081 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0042129 Census Yes 160 0.163 562 104 0.185 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0042129 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD209 CD209 Q9NNX6 CD209 antigen chr19 GO:0042129 Census Yes 116 0.287 42 8 0.19 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0042129 Census Yes 29 0.1 54 9 0.167 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0042129 Census Yes 42 0.191 18 10 0.556 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0042129 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0042129 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD81 CD81 P60033 CD81 antigen chr11 GO:0042129 Not Cancer Driver No 28 0.119 0 0 0.0 0
CLC CLC Q05315 Galectin-10 chr19 GO:0042129 Not Cancer Driver No 29 0.204 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0042129 Not Cancer Driver No 64 0.163 135 14 0.104 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0042129 Census, Compendium Yes 415 0.531 288 301 1.045 14
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0042129 Not Cancer Driver No 32 0.14 10 1 0.1 0
EPO EPO P01588 Erythropoietin chr7 GO:0042129 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0042129 Census, Compendium Yes 275 0.219 314 41 0.131 1
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0042129 Not Cancer Driver No 26 0.125 45 10 0.222 1
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0042129 Not Cancer Driver No 38 0.088 186 16 0.086 10
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0042129 Not Cancer Driver No 108 0.13 83 7 0.084 0
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0042129 Not Cancer Driver No 85 0.205 57 10 0.175 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0042129 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0042129 Not Cancer Driver No 63 0.176 138 39 0.283 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0042129 Not Cancer Driver No 25 0.116 203 20 0.099 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0042129 Not Cancer Driver No 25 0.083 30 2 0.067 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0042129 Not Cancer Driver No 82 0.203 41 8 0.195 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0042129 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0042129 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0042129 Not Cancer Driver No 32 0.098 171 24 0.14 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0042129 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0042129 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0042129 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0042129 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0042129 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0042129 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0042129 Census Yes 24 0.157 6 1 0.167 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0042129 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0042129 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0042129 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0042129 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0042129 Not Cancer Driver No 51 0.188 131 29 0.221 2
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0042129 Compendium Yes 49 0.151 228 31 0.136 2
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0042129 Not Cancer Driver No 95 0.105 335 42 0.125 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0042129 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0042129 Census, Compendium Yes 167 0.149 63 10 0.159 7
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0042129 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:0042129 Not Cancer Driver No 14 0.103 54 5 0.093 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0042129 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGALS9B_ENST00000423676 LGALS9B Q3B8N2 Galectin-9B chr17 GO:0042129 Not Cancer Driver No 43 0.121 86 19 0.221 0
LGALS9C LGALS9C Q6DKI2 Galectin-9C chr17 GO:0042129 Not Cancer Driver No 32 0.09 80 6 0.075 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0042129 Not Cancer Driver No 162 0.362 277 115 0.415 0
LMO1 LMO1 P25800 Rhombotin-1 chr11 GO:0042129 Census Yes 23 0.147 0 0 0.0 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0042129 Not Cancer Driver No 130 0.196 28 4 0.143 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0042129 Not Cancer Driver No 79 0.111 444 40 0.09 1
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0042129 Census, Compendium Yes 33 0.121 41 13 0.317 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0042129 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRNP PRNP P04156 Major prion protein chr20 GO:0042129 Not Cancer Driver No 36 0.142 115 7 0.061 18
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0042129 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0042129 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0042129 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0042129 Not Cancer Driver No 31 0.161 0 0 0.0 2
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 GO:0042129 Not Cancer Driver No 114 0.113 536 68 0.127 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0042129 Not Cancer Driver No 158 0.139 796 115 0.144 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0042129 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0042129 Not Cancer Driver No 66 0.127 295 39 0.132 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0042129 Not Cancer Driver No 22 0.091 48 4 0.083 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0042129 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 GO:0042129 Not Cancer Driver No 109 0.123 586 72 0.123 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0042129 Not Cancer Driver No 56 0.121 139 14 0.101 81
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0042129 Not Cancer Driver No 82 0.245 64 10 0.156 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0042129 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0042129 Not Cancer Driver No 173 0.13 362 54 0.149 2
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0042129 Census, Compendium Yes 93 0.118 144 19 0.132 5
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0042129 Census Yes 96 0.151 131 27 0.206 5
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0042129 Census, Compendium Yes 106 0.187 60 16 0.267 25
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:0042129 Not Cancer Driver No 188 0.117 448 47 0.105 0
TMIGD2 TMIGD2 Q96BF3 Transmembrane and immunoglobulin domain-containing protein 2 chr19 GO:0042129 Not Cancer Driver No 57 0.202 120 32 0.267 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0042129 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0042129 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0042129 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF8 TNFSF8 P32971 Tumor necrosis factor ligand superfamily member 8 chr9 GO:0042129 Not Cancer Driver No 34 0.145 30 2 0.067 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0042129 Not Cancer Driver No 32 0.126 39 4 0.103 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0042129 Not Cancer Driver No 27 0.121 19 3 0.158 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0042129 Not Cancer Driver No 148 0.125 213 29 0.136 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0042129 Not Cancer Driver No 52 0.167 135 19 0.141 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0042129 Not Cancer Driver No 28 0.246 35 11 0.314 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0042129 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0042129 Compendium Yes 103 0.191 353 70 0.198 0