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Total number of protein in "GO:1902532" GO term:  357

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:1902532 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:1902532 Census, Compendium Yes 171 0.145 641 70 0.109 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:1902532 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:1902532 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:1902532 Not Cancer Driver No 123 0.137 135 13 0.096 0
ADGRG3 ADGRG3 Q86Y34 Adhesion G protein-coupled receptor G3 chr16 GO:1902532 Not Cancer Driver No 87 0.158 42 5 0.119 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:1902532 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:1902532 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:1902532 Not Cancer Driver No 130 0.279 40 8 0.2 0
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:1902532 Not Cancer Driver No 36 0.118 87 9 0.103 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:1902532 Compendium Yes 45 0.084 307 13 0.042 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:1902532 Census, Compendium Yes 108 0.225 158 24 0.152 4
AMBP AMBP P02760 Protein AMBP chr9 GO:1902532 Not Cancer Driver No 57 0.162 61 15 0.246 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:1902532 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:1902532 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:1902532 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:1902532 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:1902532 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARMC10 ARMC10 Q8N2F6 Armadillo repeat-containing protein 10 chr7 GO:1902532 Not Cancer Driver No 39 0.114 58 4 0.069 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:1902532 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:1902532 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:1902532 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:1902532 Census, Compendium Yes 469 0.153 225 39 0.173 41
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:1902532 Not Cancer Driver No 37 0.083 63 7 0.111 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:1902532 Not Cancer Driver No 150 0.191 394 73 0.185 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:1902532 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:1902532 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:1902532 Census, Compendium Yes 134 0.19 328 67 0.204 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:1902532 Not Cancer Driver No 81 0.207 0 0 0.0 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:1902532 Not Cancer Driver No 23 0.118 74 9 0.122 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:1902532 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMT2 BMT2 Q1RMZ1 S-adenosylmethionine sensor upstream of mTORC1 chr7 GO:1902532 Not Cancer Driver No 65 0.16 81 10 0.123 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:1902532 Not Cancer Driver No 92 0.176 24 2 0.083 0
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:1902532 Not Cancer Driver No 61 0.137 35 6 0.171 0
C16orf72 TAPR1 Q14CZ0 Telomere attrition and p53 response 1 protein chr16 GO:1902532 Not Cancer Driver No 33 0.12 201 21 0.104 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:1902532 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:1902532 Not Cancer Driver No 19 0.08 101 5 0.05 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:1902532 Not Cancer Driver No 42 0.171 73 14 0.192 0
C3orf33 C3orf33 Q6P1S2 Protein C3orf33 chr3 GO:1902532 Not Cancer Driver No 30 0.102 23 0 0.0 0
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:1902532 Not Cancer Driver No 27 0.082 39 5 0.128 0
CASTOR3 CASTOR3 Q8NAP1 Putative protein CASTOR 3 chr7 GO:1902532 Not Cancer Driver No 18 0.11 1 0 0.0 0
CAVIN3 CAVIN3 Q969G5 Caveolae-associated protein 3 chr11 GO:1902532 Not Cancer Driver No 22 0.084 234 19 0.081 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:1902532 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:1902532 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:1902532 Not Cancer Driver No 66 0.185 19 1 0.053 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 GO:1902532 Not Cancer Driver No 173 0.204 290 66 0.228 0
CD44 CD44 P16070 CD44 antigen chr11 GO:1902532 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:1902532 Census Yes 31 0.105 185 20 0.108 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:1902532 Not Cancer Driver No 17 0.102 44 3 0.068 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:1902532 Not Cancer Driver No 60 0.11 377 35 0.093 5
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:1902532 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:1902532 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:1902532 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:1902532 Not Cancer Driver No 76 0.159 23 6 0.261 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:1902532 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:1902532 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:1902532 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:1902532 Not Cancer Driver No 72 0.13 269 43 0.16 0
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:1902532 Not Cancer Driver No 74 0.138 80 7 0.087 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:1902532 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:1902532 Census Yes 68 0.131 372 50 0.134 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:1902532 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:1902532 Not Cancer Driver No 41 0.091 18 1 0.056 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:1902532 Census, Compendium Yes 123 0.16 167 23 0.138 3
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:1902532 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:1902532 Census, Compendium Yes 116 0.121 213 31 0.146 3
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:1902532 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:1902532 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:1902532 Not Cancer Driver No 163 0.195 598 127 0.212 1
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:1902532 Not Cancer Driver No 102 0.114 485 61 0.126 4
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:1902532 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:1902532 Census Yes 29 0.172 160 27 0.169 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:1902532 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:1902532 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:1902532 Census, Compendium Yes 133 0.201 301 47 0.156 18
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 GO:1902532 Not Cancer Driver No 226 0.141 575 91 0.158 7
DEPTOR DEPTOR Q8TB45 DEP domain-containing mTOR-interacting protein chr8 GO:1902532 Not Cancer Driver No 57 0.139 125 12 0.096 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:1902532 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKG DGKG P49619 Diacylglycerol kinase gamma chr3 GO:1902532 Not Cancer Driver No 160 0.202 182 43 0.236 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:1902532 Not Cancer Driver No 62 0.091 84 8 0.095 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:1902532 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:1902532 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:1902532 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:1902532 Not Cancer Driver No 37 0.093 153 16 0.105 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:1902532 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:1902532 Not Cancer Driver No 88 0.22 45 17 0.378 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:1902532 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:1902532 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:1902532 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:1902532 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:1902532 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:1902532 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:1902532 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:1902532 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:1902532 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:1902532 Not Cancer Driver No 40 0.104 109 12 0.11 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:1902532 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:1902532 Not Cancer Driver No 77 0.128 294 39 0.133 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:1902532 Not Cancer Driver No 87 0.148 193 20 0.104 0
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 GO:1902532 Not Cancer Driver No 181 0.131 835 130 0.156 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:1902532 Not Cancer Driver No 50 0.126 186 13 0.07 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:1902532 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:1902532 Not Cancer Driver No 51 0.118 21 2 0.095 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:1902532 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:1902532 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:1902532 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:1902532 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:1902532 Not Cancer Driver No 167 0.118 967 118 0.122 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:1902532 Not Cancer Driver No 55 0.119 297 37 0.125 0
EZR EZR P15311 Ezrin chr6 GO:1902532 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:1902532 Not Cancer Driver No 55 0.139 7 2 0.286 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:1902532 Compendium Yes 122 0.174 22 3 0.136 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 GO:1902532 Not Cancer Driver No 30 0.108 0 0 0.0 0
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:1902532 Not Cancer Driver No 51 0.111 0 0 0.0 10
FLCN FLCN Q8NFG4 Folliculin chr17 GO:1902532 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:1902532 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:1902532 Census, Compendium Yes 81 0.124 584 75 0.128 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:1902532 Not Cancer Driver No 92 0.155 166 27 0.163 0
GPATCH3 GPATCH3 Q96I76 G patch domain-containing protein 3 chr1 GO:1902532 Not Cancer Driver No 64 0.122 354 48 0.136 0
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:1902532 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:1902532 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:1902532 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:1902532 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:1902532 Not Cancer Driver No 39 0.105 150 15 0.1 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:1902532 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:1902532 Not Cancer Driver No 32 0.152 0 0 0.0 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:1902532 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:1902532 Not Cancer Driver No 91 0.096 570 50 0.088 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:1902532 Not Cancer Driver No 173 0.125 974 135 0.139 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:1902532 Census Yes 38 0.097 248 17 0.069 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:1902532 Census Yes 118 0.143 435 51 0.117 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:1902532 Not Cancer Driver No 128 0.105 559 51 0.091 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:1902532 Not Cancer Driver No 94 0.278 85 22 0.259 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 GO:1902532 Not Cancer Driver No 53 0.15 233 32 0.137 1
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 GO:1902532 Not Cancer Driver No 31 0.086 251 15 0.06 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:1902532 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:1902532 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:1902532 Compendium Yes 44 0.096 127 9 0.071 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:1902532 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:1902532 Not Cancer Driver No 132 0.132 373 47 0.126 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:1902532 Not Cancer Driver No 33 0.115 63 10 0.159 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:1902532 Not Cancer Driver No 51 0.15 193 28 0.145 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:1902532 Not Cancer Driver No 33 0.118 169 26 0.154 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:1902532 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:1902532 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:1902532 Not Cancer Driver No 15 0.136 5 1 0.2 22
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:1902532 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:1902532 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:1902532 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:1902532 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:1902532 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:1902532 Not Cancer Driver No 390 0.141 581 76 0.131 6
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:1902532 Not Cancer Driver No 183 0.135 804 100 0.124 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:1902532 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:1902532 Not Cancer Driver No 33 0.1 95 10 0.105 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:1902532 Not Cancer Driver No 67 0.079 291 28 0.096 3
KLHL31 KLHL31 Q9H511 Kelch-like protein 31 chr6 GO:1902532 Not Cancer Driver No 69 0.109 32 1 0.031 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:1902532 Not Cancer Driver No 44 0.101 21 2 0.095 0
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 GO:1902532 Not Cancer Driver No 44 0.087 211 4 0.019 2
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:1902532 Not Cancer Driver No 25 0.124 0 0 0.0 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 GO:1902532 Not Cancer Driver No 58 0.086 428 36 0.084 0
LITAF_ENST00000570904 LITAF Q99732 Lipopolysaccharide-induced tumor necrosis factor-alpha factor chr16 GO:1902532 Not Cancer Driver No 21 0.13 67 6 0.09 5
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:1902532 Not Cancer Driver No 30 0.207 1 0 0.0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:1902532 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:1902532 Census Yes 95 0.186 84 12 0.143 0
MAD2L1BP_ENST00000372171 MAD2L1BP Q15013 MAD2L1-binding protein chr6 GO:1902532 Not Cancer Driver No 26 0.095 55 7 0.127 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:1902532 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:1902532 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:1902532 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:1902532 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:1902532 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:1902532 Not Cancer Driver No 79 0.111 444 40 0.09 1
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:1902532 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 GO:1902532 Not Cancer Driver No 92 0.122 376 49 0.13 1
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:1902532 Not Cancer Driver No 40 0.1 179 10 0.056 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:1902532 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:1902532 Census, Compendium Yes 287 0.233 749 159 0.212 3
MEN1 MEN1 O00255 Menin chr11 GO:1902532 Census, Compendium Yes 73 0.119 228 15 0.066 90
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:1902532 Census, Compendium Yes 226 0.163 62 15 0.242 19
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:1902532 Not Cancer Driver No 4 0.035 0 0 0.0 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:1902532 Not Cancer Driver No 45 0.108 145 16 0.11 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:1902532 Not Cancer Driver No 68 0.181 64 11 0.172 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:1902532 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:1902532 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:1902532 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:1902532 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:1902532 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:1902532 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:1902532 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOC MYOC Q99972 Myocilin chr1 GO:1902532 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:1902532 Not Cancer Driver No 49 0.164 223 39 0.175 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:1902532 Not Cancer Driver No 50 0.189 197 38 0.193 2
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:1902532 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 GO:1902532 Not Cancer Driver No 45 0.121 111 8 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:1902532 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:1902532 Census, Compendium Yes 228 0.377 402 62 0.154 4
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:1902532 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:1902532 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:1902532 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:1902532 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:1902532 Not Cancer Driver No 158 0.162 94 13 0.138 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:1902532 Not Cancer Driver No 17 0.08 6 0 0.0 0
NMI NMI Q13287 N-myc-interactor chr2 GO:1902532 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:1902532 Not Cancer Driver No 20 0.096 179 17 0.095 2
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:1902532 Census, Compendium Yes 101 0.214 349 64 0.183 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:1902532 Not Cancer Driver No 59 0.123 391 41 0.105 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:1902532 Not Cancer Driver No 78 0.128 47 8 0.17 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:1902532 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 GO:1902532 Compendium Yes 37 0.097 10 3 0.3 1
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 GO:1902532 Not Cancer Driver No 45 0.079 158 22 0.139 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:1902532 Not Cancer Driver No 114 0.119 131 17 0.13 60
OTUD3 OTUD3 Q5T2D3 OTU domain-containing protein 3 chr1 GO:1902532 Not Cancer Driver No 43 0.108 280 25 0.089 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:1902532 Not Cancer Driver No 42 0.102 82 11 0.134 7
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:1902532 Not Cancer Driver No 11 0.058 30 0 0.0 5
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:1902532 Not Cancer Driver No 23 0.071 92 6 0.065 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:1902532 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:1902532 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:1902532 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:1902532 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:1902532 Not Cancer Driver No 32 0.113 238 23 0.097 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:1902532 Not Cancer Driver No 58 0.102 199 19 0.095 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:1902532 Census Yes 160 0.124 948 116 0.122 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:1902532 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHLDA3 PHLDA3 Q9Y5J5 Pleckstrin homology-like domain family A member 3 chr1 GO:1902532 Not Cancer Driver No 20 0.157 0 0 0.0 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 GO:1902532 Not Cancer Driver No 134 0.078 744 29 0.039 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:1902532 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:1902532 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:1902532 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:1902532 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:1902532 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLEK PLEK P08567 Pleckstrin chr2 GO:1902532 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:1902532 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:1902532 Not Cancer Driver No 2 0.021 0 0 0.0 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:1902532 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:1902532 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:1902532 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:1902532 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:1902532 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:1902532 Not Cancer Driver No 41 0.133 12 1 0.083 8
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:1902532 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:1902532 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:1902532 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSCA PSCA O43653 Prostate stem cell antigen chr8 GO:1902532 Not Cancer Driver No 9 0.079 0 0 0.0 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:1902532 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:1902532 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:1902532 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:1902532 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:1902532 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:1902532 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:1902532 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:1902532 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:1902532 Not Cancer Driver No 172 0.262 73 28 0.384 0
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:1902532 Not Cancer Driver No 23 0.128 30 9 0.3 0
PYDC2 PYDC2 Q56P42 Pyrin domain-containing protein 2 chr3 GO:1902532 Not Cancer Driver No 20 0.206 26 5 0.192 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:1902532 Not Cancer Driver No 101 0.13 106 16 0.151 4
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:1902532 Not Cancer Driver No 34 0.107 13 0 0.0 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:1902532 Not Cancer Driver No 73 0.1 413 30 0.073 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:1902532 Not Cancer Driver No 73 0.076 505 48 0.095 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:1902532 Not Cancer Driver No 90 0.276 126 44 0.349 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:1902532 Not Cancer Driver No 26 0.103 104 7 0.067 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:1902532 Compendium Yes 75 0.136 400 48 0.12 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:1902532 Not Cancer Driver No 50 0.138 150 21 0.14 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:1902532 Not Cancer Driver No 57 0.101 309 37 0.12 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:1902532 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:1902532 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:1902532 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:1902532 Not Cancer Driver No 61 0.3 34 11 0.324 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:1902532 Not Cancer Driver No 30 0.081 112 7 0.062 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:1902532 Not Cancer Driver No 180 0.242 136 36 0.265 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:1902532 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:1902532 Not Cancer Driver No 66 0.101 115 15 0.13 0
SCAI_ENST00000336505 SCAI Q8N9R8 Protein SCAI chr9 GO:1902532 Not Cancer Driver No 95 0.157 117 13 0.111 0
SEC14L1_ENST00000436233 SEC14L1 Q92503 SEC14-like protein 1 chr17 GO:1902532 Not Cancer Driver No 104 0.145 82 16 0.195 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:1902532 Not Cancer Driver No 7 0.037 122 6 0.049 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:1902532 Not Cancer Driver No 136 0.132 456 72 0.158 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:1902532 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:1902532 Not Cancer Driver No 62 0.156 0 0 0.0 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:1902532 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:1902532 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:1902532 Not Cancer Driver No 84 0.171 44 4 0.091 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:1902532 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:1902532 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP5 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:1902532 Not Cancer Driver No 26 0.082 7 3 0.429 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:1902532 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:1902532 Not Cancer Driver No 151 0.207 455 101 0.222 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:1902532 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:1902532 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:1902532 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:1902532 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:1902532 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:1902532 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:1902532 Census, Compendium Yes 198 0.359 195 17 0.087 8
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:1902532 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:1902532 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:1902532 Not Cancer Driver No 32 0.144 25 5 0.2 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:1902532 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:1902532 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:1902532 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:1902532 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:1902532 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:1902532 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:1902532 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY3 SPRY3 O43610 Protein sprouty homolog 3 chrX GO:1902532 Not Cancer Driver No 96 0.333 135 40 0.296 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:1902532 Not Cancer Driver No 34 0.114 134 20 0.149 7
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:1902532 Not Cancer Driver No 51 0.12 139 16 0.115 6
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:1902532 Census, Compendium Yes 75 0.173 135 14 0.104 9
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:1902532 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN3 STMN3 Q9NZ72 Stathmin-3 chr20 GO:1902532 Not Cancer Driver No 26 0.144 152 25 0.164 0
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:1902532 Not Cancer Driver No 27 0.186 12 4 0.333 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:1902532 Not Cancer Driver No 63 0.102 284 32 0.113 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:1902532 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:1902532 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:1902532 Not Cancer Driver No 48 0.191 189 34 0.18 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:1902532 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:1902532 Not Cancer Driver No 58 0.13 192 32 0.167 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:1902532 Not Cancer Driver No 188 0.161 320 58 0.181 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:1902532 Not Cancer Driver No 55 0.084 280 26 0.093 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:1902532 Not Cancer Driver No 88 0.129 173 25 0.145 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:1902532 Not Cancer Driver No 43 0.204 3 1 0.333 5
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:1902532 Not Cancer Driver No 66 0.115 91 14 0.154 2
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:1902532 Not Cancer Driver No 292 0.348 0 0 0.0 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:1902532 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:1902532 Not Cancer Driver No 49 0.102 22 8 0.364 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:1902532 Census Yes 7 0.159 44 7 0.159 0
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:1902532 Not Cancer Driver No 35 0.111 39 5 0.128 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:1902532 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:1902532 Not Cancer Driver No 85 0.134 625 83 0.133 0
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:1902532 Not Cancer Driver No 17 0.099 43 6 0.14 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:1902532 Not Cancer Driver No 74 0.105 110 11 0.1 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:1902532 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:1902532 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:1902532 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM40_ENST00000376724 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 GO:1902532 Not Cancer Driver No 44 0.171 84 12 0.143 0
TSC2 TSC2 P49815 Tuberin chr16 GO:1902532 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSPAN6 TSPAN6 O43657 Tetraspanin-6 chrX GO:1902532 Not Cancer Driver No 34 0.139 0 0 0.0 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:1902532 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:1902532 Not Cancer Driver No 21 0.122 44 6 0.136 0
UACA UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 GO:1902532 Not Cancer Driver No 177 0.125 863 101 0.117 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:1902532 Not Cancer Driver No 26 0.085 100 7 0.07 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:1902532 Not Cancer Driver No 137 0.1 425 39 0.092 0
VGLL4_ENST00000273038 VGLL4 Q14135 Transcription cofactor vestigial-like protein 4 chr3 GO:1902532 Not Cancer Driver No 40 0.138 276 38 0.138 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:1902532 Not Cancer Driver No 88 0.172 20 5 0.25 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:1902532 Not Cancer Driver No 65 0.137 180 18 0.1 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:1902532 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:1902532 Census, Compendium Yes 223 0.097 1868 167 0.089 0
WTIP WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 GO:1902532 Not Cancer Driver No 32 0.074 217 2 0.009 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 GO:1902532 Not Cancer Driver No 147 0.132 550 81 0.147 0
WWC2 WWC2 Q6AWC2 Protein WWC2 chr4 GO:1902532 Not Cancer Driver No 120 0.101 654 79 0.121 0
WWC3 WWC3 Q9ULE0 Protein WWC3 chrX GO:1902532 Not Cancer Driver No 214 0.196 638 114 0.179 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:1902532 Not Cancer Driver No 19 0.073 169 9 0.053 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:1902532 Not Cancer Driver No 279 0.209 134 24 0.179 1
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:1902532 Not Cancer Driver No 49 0.132 359 47 0.131 0
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 GO:1902532 Not Cancer Driver No 29 0.09 233 13 0.056 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:1902532 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:1902532 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:1902532 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:1902532 Not Cancer Driver No 114 0.201 91 19 0.209 0