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For "tcga_isimpre" total number of roi found:  2211

Identifier UniProt Accession UniProt Gene UniProt Name Chromosome Database Cancer Driver region region length P value Percent of disorder Missense mutations in the region Percent of missense mutations All mutations Sig mutated Cancertypes Cancertypes in region
BRAF P15056 BRAF Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 594-601 8 0.00e+00 87.5 637 80.53 791 SKCM, THCA SKCM, COAD, STAD, BLCA, LUSC, GBM, LGG, THCA, UCEC, LUAD, PRAD, KIRC, DLBC, HNSC, READ
IDH1 O75874 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 Census, Compendium Yes 132-132 1 0.00e+00 0.0 495 89.51 553 LGG PRAD, LGG, GBM, SKCM, BRCA, UCEC, LAML, LUAD, SARC, BLCA, LIHC, COAD
KRAS P01116 KRAS GTPase KRas chr12 Census, Compendium Yes 12-13 2 0.00e+00 0.0 665 84.39 788 COAD, PAAD, LUAD LIHC, OV, READ, COAD, PRAD, LGG, LAML, REO, CESC, GBM, LUSC, SKCM, KIRC, THCA, SARC, STAD, BRCA, BLCA, PAAD, LUAD, UCEC
TP53_ENST00000445888 P04637 TP53 Cellular tumor antigen p53 chr17 Census, Compendium Yes 105-286 182 0.00e+00 13.74 2796 96.58 2895 BLCA, LUSC, LGG, READ, COAD, HNSC, UCEC, BRCA, OV, STAD, GBM, LUAD DLBC, BLCA, LUSC, LAML, LGG, READ, COAD, HNSC, OAD, SKCM, COT, CESC, PAAD, KICH, SARC, UCEC, BRCA, PRAD, KIRC, OV, STAD, GBM, LUAD, LIHC
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 542-546 5 7.14e-198 0.0 602 35.9 1677 BRCA LGG, SARC, SKCM, LUSC, CESC, PRAD, OV, LIHC, GBM, STAD, HNSC, BLCA, UCEC, LUAD, BRCA, KIRC, COAD, READ
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1043-1049 7 1.83e-102 0.0 378 22.54 1677 BRCA LUAD, BRCA, KIRC, READ, COAD, HNSC, BLCA, UCEC, GBM, STAD, LIHC, PRAD, THCA, OV, SKCM, LUSC, CESC, LGG, PAAD, SARC
CTNNB1_ENST00000643977 P35222 CTNNB1 Catenin beta-1 chr3 Census, Compendium Yes 31-46 16 1.15e-99 100.0 263 63.37 415 LIHC, UCEC BLCA, COAD, PAAD, LUSC, CESC, HNSC, SKCM, STAD, READ, LIHC, LUAD, UCEC, PRAD
NRAS P01111 NRAS GTPase NRas chr1 Census, Compendium Yes 61-61 1 4.99e-93 0.0 213 75.0 284 SKCM UCEC, LGG, THCA, CESC, GBM, STAD, SARC, LUSC, LIHC, OV, SKCM, READ, LAML, BLCA, COAD, LUAD, OAD
IRF5_ENST00000402030 Q13568 IRF5 Interferon regulatory factor 5 chr7 Not Cancer Driver No 167-184 18 3.53e-76 100.0 31 33.33 93 COAD, READ COAD, REO, READ, BLCA, LAML, UCEC, OV, CESC
NEFH P12036 NEFH Neurofilament heavy polypeptide chr22 Compendium Yes 644-665 22 3.79e-67 100.0 3 2.56 117 READ, COAD SKCM, READ, COAD
TMPRSS13_ENST00000445164 Q9BYE2 TMPRSS13 Transmembrane protease serine 13 chr11 Not Cancer Driver No 77-91 15 4.24e-63 100.0 41 33.33 123 COAD, READ COAD, READ, LUAD
ERICH6B Q5W0A0 ERICH6B Glutamate-rich protein 6B chr13 Not Cancer Driver No 133-141 9 7.79e-39 100.0 148 73.63 201 READ, COAD REO, READ, COAD
PTEN P60484 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 123-142 20 1.29e-38 0.0 196 38.81 505 UCEC GBM, CESC, OV, LGG, SARC, LUSC, LUAD, COAD, BRCA, BLCA, READ, STAD, KIRC, UCEC, PRAD, HNSC, SKCM
FBXW7_ENST00000603841 Q969H0 FBXW7 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 437-546 110 1.59e-31 0.0 188 58.39 322 UCEC COAD, REO, HNSC, LUAD, CESC, BRCA, OV, READ, GBM, UCEC, LUSC, STAD, BLCA, SKCM
TBP P20226 TBP TATA-box-binding protein chr6 Not Cancer Driver No 93-99 7 5.48e-31 100.0 2 5.0 40 COAD, READ STAD, COAD, OV, LUAD, READ, REO
ATXN1 P54253 ATXN1 Ataxin-1 chr6 Not Cancer Driver No 205-225 21 6.53e-31 26.09 74 36.1 205 COAD, READ KIRC, GBM, LIHC, LUAD, SARC, COAD, HNSC, READ, BRCA, SKCM, STAD
COL18A1 P39060 COL18A1 Collagen alpha-1(XVIII) chain chr21 Not Cancer Driver No 1362-1364 3 1.19e-30 100.0 0 0.0 186 COAD, READ COAD, READ, REO, UCEC, OAD
NFE2L2 Q16236 NFE2L2 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 24-34 11 1.25e-28 45.45 94 41.23 228 LUSC PAAD, CESC, KIRC, LIHC, BLCA, HNSC, LUSC, LUAD, UCEC
CHEK2_ENST00000405598 O96017 CHEK2 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 519-536 18 2.80e-28 100.0 113 33.73 335 GBM LUAD, KIRC, GBM, OV, SKCM, HNSC
CHEK2_ENST00000405598 O96017 CHEK2 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 363-398 36 2.34e-27 52.78 135 40.3 335 GBM UCEC, LGG, PRAD, BLCA, GBM, COAD, LUAD, KIRC, THCA, HNSC, LUSC, CESC, BRCA, SKCM, READ
CACNA1B Q00975 CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B chr9 Not Cancer Driver No 996-1000 5 1.17e-26 100.0 12 2.84 423 COAD, READ COAD, READ, OAD, REO
KRT1 P04264 KRT1 Keratin, type II cytoskeletal 1 chr12 Not Cancer Driver No 548-563 16 3.23e-25 100.0 7 5.19 135 COAD, READ CESC, COAD, READ, UCEC, LUAD, REO
PHF2 O75151 PHF2 Lysine-specific demethylase PHF2 chr9 Not Cancer Driver No 992-999 8 4.48e-25 100.0 2 1.52 132 READ, COAD UCEC, READ, COAD
PIK3R1 P27986 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 555-583 29 8.81e-23 17.24 44 28.57 154 UCEC BRCA, SKCM, CESC, LUSC, OV, READ, UCEC, GBM, LGG, STAD
KCNN3_ENST00000271915 Q9UGI6 KCNN3 Small conductance calcium-activated potassium channel protein 3 chr1 Not Cancer Driver No 64-80 17 1.28e-22 100.0 19 13.87 137 COAD, READ BRCA, COAD, UCEC, OV, READ, THCA, OAD, REO
KRTAP4-5 Q9BYR2 KRTAP4-5 Keratin-associated protein 4-5 chr17 Not Cancer Driver No 69-85 17 6.37e-22 100.0 28 48.28 58 COAD, READ BRCA, LUAD, COAD, READ, UCEC
EPPK1 P58107 EPPK1 Epiplakin chr8 Not Cancer Driver No 2168-2386 219 6.50e-22 100.0 127 29.67 428 - HNSC, THCA, OV, KIRC, SKCM, UCEC, LGG, GBM, LUSC, STAD, LUAD, LIHC, BLCA, CESC, LAML, COAD, PRAD, BRCA
NFE2L2 Q16236 NFE2L2 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 77-82 6 8.31e-22 100.0 70 30.7 228 - CESC, KIRC, BRCA, LIHC, HNSC, BLCA, LUAD, UCEC, LUSC
AKT1_ENST00000349310 P31749 AKT1 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 17-23 7 1.53e-21 42.86 58 53.7 108 BRCA STAD, THCA, HNSC, BLCA, UCEC, PRAD, LUAD, CESC, BRCA, SKCM, LUSC, COAD
PIK3R1 P27986 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 440-470 31 1.61e-21 35.48 11 7.14 154 UCEC BRCA, CESC, UCEC, READ, HNSC
KMT2C_ENST00000355193 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 284-408 125 1.49e-20 100.0 127 15.17 837 - PRAD, LUAD, GBM, CESC, KIRC, COAD, SARC, SKCM, STAD, READ, BLCA, THCA, LUSC, OV, UCEC, BRCA, HNSC, LIHC
CTBS Q01459 CTBS Di-N-acetylchitobiase chr1 Not Cancer Driver No 10-33 24 5.74e-20 100.0 10 22.22 45 COAD, READ COAD, READ
PPM1E Q8WY54 PPM1E Protein phosphatase 1E chr17 Not Cancer Driver No 36-47 12 4.92e-19 100.0 5 4.39 114 READ, COAD CESC, READ, COAD, UCEC, OV, LIHC, BRCA, REO
MUC4 Q99102 MUC4 Mucin-4 chr3 Census Yes 4192-4217 26 1.23e-18 100.0 75 7.28 1030 KIRC SKCM, LUAD, BRCA, UCEC, KIRC, OV, LGG, PRAD, GBM
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 69-118 50 2.00e-18 0.0 221 13.18 1677 UCEC LIHC, THCA, OV, PRAD, CESC, LUSC, LGG, PAAD, LUAD, KIRC, READ, COAD, BRCA, BLCA, HNSC, UCEC, STAD, GBM
LURAP1L Q8IV03 LURAP1L Leucine rich adaptor protein 1-like chr9 Not Cancer Driver No 53-56 4 3.27e-18 100.0 1 3.23 31 COAD, READ UCEC, OV, COAD, READ, OAD, REO
ANKRD36C Q5JPF3 ANKRD36C Ankyrin repeat domain-containing protein 36C chr2 Not Cancer Driver No 622-641 20 5.86e-18 100.0 57 28.5 200 PRAD SKCM, PRAD, OV, LUAD, LUSC, LGG, KIRC, BRCA
POTEM A6NI47 POTEM Putative POTE ankyrin domain family member M chr14 Not Cancer Driver No 30-150 121 6.26e-17 76.61 169 56.52 299 - CESC, UCEC, HNSC, PRAD, LUSC, SKCM, LUAD, LIHC, THCA, BRCA, COAD, GBM, READ, SARC, OV, BLCA, KIRC, STAD, PAAD
FGFR3_ENST00000440486 P22607 FGFR3 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 248-249 2 9.10e-17 100.0 47 26.86 175 BLCA LUSC, BLCA, HNSC
HRAS P01112 HRAS GTPase HRas chr11 Census, Compendium Yes 12-13 2 2.72e-16 0.0 47 43.93 107 HNSC SKCM, HNSC, BRCA, BLCA, LUSC, UCEC
SPOP O43791 SPOP Speckle-type POZ protein chr17 Census, Compendium Yes 73-147 75 3.00e-16 4.0 98 66.67 147 UCEC, PRAD LUAD, UCEC, CESC, LUSC, DLBC, THCA, BRCA, BLCA, STAD, LGG, SKCM, PRAD
FLT3 P36888 FLT3 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 573-622 50 3.66e-16 34.0 16 7.77 206 LAML LAML, STAD, CESC, LUSC, OV, SKCM
RGPD3 A6NKT7 RGPD3 RanBP2-like and GRIP domain-containing protein 3 chr2 Census, Compendium Yes 741-816 76 6.02e-16 79.22 96 28.15 341 UCEC LUSC, CESC, BLCA, SKCM, UCEC, STAD, LGG, GBM, PAAD, LIHC, LUAD, BRCA, KIRC, COAD
ITPKB_ENST00000272117 P27987 ITPKB Inositol-trisphosphate 3-kinase B chr1 Not Cancer Driver No 92-96 5 8.14e-16 100.0 0 0.0 149 READ BRCA, UCEC, READ
MAML3 Q96JK9 MAML3 Mastermind-like protein 3 chr4 Not Cancer Driver No 500-510 11 1.05e-15 100.0 0 0.0 127 COAD, READ COAD, UCEC, READ
ZFPM1 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 chr16 Not Cancer Driver No 446-447 2 1.64e-15 100.0 0 0.0 51 COAD, READ COAD, READ, REO
PPP2R1A P30153 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 179-185 7 7.24e-15 0.0 52 29.05 179 UCEC UCEC, LUAD, OV, READ, HNSC, STAD, COAD, BRCA
FAM71E2 Q8N5Q1 GARIN5B Golgi associated RAB2 interactor protein 5B chr19 Not Cancer Driver No 774-785 12 1.16e-14 100.0 3 6.98 43 COAD, READ KIRC, COAD, DLBC, READ, REO
SMAD4_ENST00000398417 Q13485 SMAD4 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 351-366 16 1.20e-14 0.0 58 29.29 198 - BRCA, PAAD, HNSC, LUAD, BLCA, PRAD, READ, COAD, CESC, STAD, LIHC
ZNF429 Q86V71 ZNF429 Zinc finger protein 429 chr19 Census, Compendium Yes 547-568 22 1.69e-14 0.0 72 22.78 316 GBM SKCM, LGG, GBM, HNSC
MAML2 Q8IZL2 MAML2 Mastermind-like protein 2 chr11 Census, Compendium Yes 619-621 3 2.44e-14 100.0 1 0.68 148 READ, COAD LIHC, READ, COAD
EYS Q5T1H1 EYS Protein eyes shut homolog chr6 Not Cancer Driver No 268-581 314 3.75e-14 100.0 134 29.58 453 - READ, PAAD, KIRC, LUAD, SARC, BLCA, HNSC, STAD, OV, LIHC, UCEC, GBM, LUSC, SKCM, BRCA, CESC
EGFR P00533 EGFR Epidermal growth factor receptor chr7 Census, Compendium Yes 289-292 4 4.31e-14 0.0 47 10.54 446 GBM LGG, GBM, CESC, HNSC, BRCA
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 344-350 7 4.63e-14 0.0 79 4.71 1677 BRCA, UCEC LUAD, COAD, READ, BRCA, BLCA, HNSC, UCEC, STAD, GBM, PRAD, CESC, LUSC, SARC, LGG
ERBB2 P04626 ERBB2 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 305-313 9 5.05e-14 0.0 50 18.12 276 BLCA BLCA, LUAD, BRCA, UCEC, STAD, OV, CESC, READ, HNSC
ARHGAP5 Q13017 ARHGAP5 Rho GTPase-activating protein 5 chr14 Census, Compendium Yes 405-560 156 6.13e-14 5.73 89 35.74 249 GBM BLCA, GBM, OAD, COAD, SKCM, OV, UCEC, BRCA, STAD, READ, KIRC
PGM5 Q15124 PGM5 Phosphoglucomutase-like protein 5 chr9 Not Cancer Driver No 94-102 9 1.04e-13 0.0 63 37.28 169 STAD CESC, PRAD, STAD, BRCA, COAD, HNSC, READ, LUAD, UCEC, SARC
ADM2_ENST00000395737 Q7Z4H4 ADM2 Protein ADM2 chr22 Not Cancer Driver No 93-100 8 2.01e-13 100.0 3 21.43 14 COAD, READ LUAD, COAD, HNSC, REO, READ
BRD8 Q9H0E9 BRD8 Bromodomain-containing protein 8 chr5 Not Cancer Driver No 224-225 2 2.84e-13 100.0 38 20.11 189 BLCA BLCA
NBPF10 Q6P3W6 NBPF10 Neuroblastoma breakpoint family member 10 chr1 Not Cancer Driver No 3691-3713 23 6.85e-13 100.0 44 16.3 270 - GBM, PRAD, SKCM, UCEC, LGG, KIRC, BLCA, READ, LUAD, COAD
CDC42EP1 Q00587 CDC42EP1 Cdc42 effector protein 1 chr22 Not Cancer Driver No 256-264 9 9.77e-13 100.0 2 3.77 53 COAD BRCA, COAD, UCEC, READ
ZNF814 B7Z6K7 ZNF814 Zinc finger protein 814 chr19 Compendium Yes 314-323 10 1.11e-12 0.0 49 25.52 192 COAD, READ CESC, COAD, READ
EEF1B2_ENST00000236957 P24534 EEF1B2 Elongation factor 1-beta chr2 Not Cancer Driver No 43-46 4 2.10e-12 0.0 33 51.56 64 KIRC, LUAD KIRC, LGG, PRAD, SKCM, UCEC, LUAD
RGPD8 O14715 RGPD8 RANBP2-like and GRIP domain-containing protein 8 chr2 Not Cancer Driver No 1760-1762 3 4.15e-12 100.0 33 25.58 129 PRAD LGG, UCEC, PRAD, LUAD, SKCM, GBM, KIRC
AGAP9 Q5VTM2-2 AGAP9 Isoform 2 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9 chr10 Not Cancer Driver No 127-132 6 4.70e-12 100.0 24 85.71 28 PRAD SKCM, CESC, UCEC, LGG, KIRC, LUAD, PRAD
HRAS P01112 HRAS GTPase HRas chr11 Census, Compendium Yes 60-61 2 8.72e-12 0.0 36 33.64 107 THCA PRAD, LUAD, THCA, SKCM, HNSC, LUSC, COAD, BLCA
U2AF1 Q01081 U2AF1 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 28-38 11 1.04e-11 9.09 37 52.86 70 LUAD BLCA, PAAD, LUAD, STAD, LAML, HNSC, PRAD, CESC, UCEC
AR P10275 AR Androgen receptor chrX Census, Compendium Yes 28-95 68 1.27e-11 79.41 44 22.45 196 COAD, READ LUAD, COAD, SKCM, LUSC, UCEC, REO, READ, BRCA, KIRC, BLCA, OAD
EYS Q5T1H1 EYS Protein eyes shut homolog chr6 Not Cancer Driver No 3-217 215 1.32e-11 100.0 98 21.63 453 - HNSC, COAD, STAD, BLCA, LUAD, KIRC, READ, BRCA, CESC, SKCM, PRAD, LUSC, UCEC, OV, LIHC
AMY1C P0DTE8 AMY1C Alpha-amylase 1C chr1 Not Cancer Driver No 297-366 70 1.62e-11 0.0 37 100.0 37 SKCM COAD, LIHC, SKCM, CESC, HNSC, UCEC, GBM, LUAD, LUSC, STAD, KIRC
HACD1 B0YJ81 HACD1 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 chr10 Not Cancer Driver No 64-70 7 2.23e-11 62.5 56 57.73 97 COAD, READ COAD, READ
GPRIN1 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 chr5 Not Cancer Driver No 230-243 14 2.31e-11 100.0 21 18.1 116 COAD, READ COAD, READ, KIRC, BLCA
POTEG Q6S5H5 POTEG POTE ankyrin domain family member G chr14 Not Cancer Driver No 53-119 67 3.16e-11 100.0 54 58.06 93 LUAD LUSC, UCEC, SKCM, LUAD, BLCA, PRAD, PAAD, BRCA, COAD, HNSC, STAD, KIRC
PRAMEF6 Q5VXH4 PRAMEF6 PRAME family member 6 chr1 Not Cancer Driver No 96-162 67 3.73e-11 53.73 38 80.85 47 LUAD BLCA, LUSC, HNSC, SKCM, BRCA, STAD, CESC, KIRC, LUAD
TENT5A Q96IP4 TENT5A Terminal nucleotidyltransferase 5A chr6 Not Cancer Driver No 36-45 10 3.91e-11 100.0 0 0.0 43 READ, COAD READ, COAD, REO
TPRX1 Q8N7U7 TPRX1 Tetra-peptide repeat homeobox protein 1 chr19 Not Cancer Driver No 201-212 12 6.79e-11 100.0 12 15.79 76 READ, COAD READ, COAD, BRCA, UCEC, KIRC, REO
KRTAP4-3 Q9BYR4 KRTAP4-3 Keratin-associated protein 4-3 chr17 Not Cancer Driver No 20-31 12 7.82e-11 100.0 39 59.09 66 READ, COAD READ, STAD, BLCA, COAD
TNRC6A Q8NDV7 TNRC6A Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 115-118 4 9.70e-11 100.0 5 1.72 290 READ, COAD READ, LUSC, COAD
NRAS P01111 NRAS GTPase NRas chr1 Census, Compendium Yes 12-13 2 9.99e-11 0.0 43 15.14 284 READ READ, LAML, BLCA, COAD, STAD, UCEC, LGG, LUSC, SKCM
IRS4 O14654 IRS4 Insulin receptor substrate 4 chrX Census, Compendium Yes 635-640 6 1.49e-10 100.0 35 11.59 302 GBM LUSC, GBM
CIC Q96RK0 CIC Protein capicua homolog chr19 Census, Compendium Yes 201-235 35 1.54e-10 0.0 47 17.03 276 LGG STAD, UCEC, LGG
SMPD1 P17405 SMPD1 Sphingomyelin phosphodiesterase chr11 Not Cancer Driver No 36-49 14 1.54e-10 62.5 9 8.74 103 COAD CESC, READ, UCEC, COAD
RALY Q9UKM9 RALY RNA-binding protein Raly chr20 Not Cancer Driver No 230-236 7 1.80e-10 100.0 20 29.85 67 COAD, READ COAD, READ, LAML, OAD, OV, BRCA, LUSC
ZNF814 B7Z6K7 ZNF814 Zinc finger protein 814 chr19 Compendium Yes 404-404 1 1.81e-10 100.0 30 15.62 192 GBM KIRC, GBM, SKCM, LGG, PRAD, LUAD
EGFR P00533 EGFR Epidermal growth factor receptor chr7 Census, Compendium Yes 596-598 3 2.56e-10 100.0 36 8.07 446 GBM LGG, GBM
SMARCA4 P51532 SMARCA4 Transcription activator BRG1 chr19 Census, Compendium Yes 1135-1254 120 3.52e-10 24.17 82 23.16 354 - STAD, LGG, LIHC, COAD, LUAD, THCA, PAAD, LUSC, BRCA, SKCM, READ, HNSC, BLCA, PRAD, UCEC, OV, KIRC, GBM
ELOA3 A0A8I5KDJ8 ELOA3 Uncharacterized protein chr18 Not Cancer Driver No 353-392 40 3.74e-10 100.0 50 46.73 107 SKCM STAD, UCEC, BLCA, SKCM, LUSC, OV, CESC, READ, LIHC, GBM, COAD, LUAD, KIRC, BRCA
KANK3 Q6NY19 KANK3 KN motif and ankyrin repeat domain-containing protein 3 chr19 Not Cancer Driver No 489-497 9 3.91e-10 100.0 2 3.33 60 COAD COAD, UCEC
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 726-726 1 4.48e-10 0.0 35 2.09 1677 BRCA LIHC, CESC, LUSC, COAD, READ, BRCA, LUAD, UCEC, BLCA, HNSC
KNSTRN Q9Y448 KNSTRN Small kinetochore-associated protein chr15 Census Yes 4-34 31 4.56e-10 100.0 42 55.26 76 SKCM BRCA, SKCM, STAD, READ, LUAD, THCA, BLCA, HNSC
KRTAP4-8 Q9BYQ9 KRTAP4-8 Keratin-associated protein 4-8 chr17 Not Cancer Driver No 67-130 64 5.18e-10 100.0 66 77.65 85 LUAD BLCA, GBM, KIRC, BRCA, READ, SKCM, LGG, STAD, LUAD, UCEC, COAD, CESC, PRAD
NCOR2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 1837-1837 1 5.69e-10 100.0 0 0.0 384 READ, COAD READ, COAD
NPIPB5 A8MRT5 NPIPB5 Nuclear pore complex-interacting protein family member B5 chr16 Not Cancer Driver No 501-568 68 5.76e-10 100.0 21 77.78 27 - LUSC, BLCA, UCEC, BRCA, HNSC, PRAD, KIRC, SKCM, CESC, LUAD, LIHC, OV
BCOR Q6W2J9 BCOR BCL-6 corepressor chrX Census, Compendium Yes 1454-1459 6 6.03e-10 16.67 35 11.99 292 UCEC DLBC, UCEC, LUAD, LUSC, CESC
HIF1A_ENST00000337138 Q16665 HIF1A Hypoxia-inducible factor 1-alpha chr14 Census Yes 213-213 1 6.81e-10 100.0 54 37.24 145 GBM GBM
NUMBL Q9Y6R0 NUMBL Numb-like protein chr19 Not Cancer Driver No 445-453 9 6.89e-10 100.0 1 2.38 42 READ, COAD UCEC, READ, COAD, OV
ATN1_ENST00000396684 P54259 ATN1 Atrophin-1 chr12 Not Cancer Driver No 496-502 7 7.19e-10 100.0 7 4.96 141 COAD, READ BLCA, COAD, BRCA, UCEC, READ, KIRC, OAD
PARG_ENST00000616448 Q86W56 PARG Poly(ADP-ribose) glycohydrolase chr10 Not Cancer Driver No 584-591 8 9.76e-10 0.0 24 40.0 60 LUAD SKCM, KIRC, LGG, GBM, LUAD, LUSC, PRAD
PCMTD1_ENST00000522514 Q96MG8 PCMTD1 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 chr8 Compendium Yes 258-295 38 1.94e-09 78.95 40 44.44 90 BLCA UCEC, SKCM, BLCA, KIRC, LUAD, LIHC, STAD, HNSC, LGG, GBM, PRAD, LUSC
FGFR2_ENST00000358487 P21802 FGFR2 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 247-254 8 2.42e-09 62.5 35 14.71 238 UCEC SKCM, UCEC, LUSC, LUAD, OV, BRCA
IDH2 P48735 IDH2 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 172-172 1 2.73e-09 0.0 24 32.0 75 LGG LIHC, LAML, LGG
CFAP54 Q96N23 CFAP54 Cilia- and flagella-associated protein 54 chr12 Not Cancer Driver No 1609-1784 176 2.76e-09 100.0 68 20.12 338 SKCM LIHC, GBM, SKCM, KICH, UCEC, COAD, HNSC, LUAD, CESC, PRAD, BRCA, SARC, STAD, BLCA, KIRC, LUSC
ZNF595 Q8IYB9 ZNF595 Zinc finger protein 595 chr4 Not Cancer Driver No 2-90 89 3.20e-09 64.04 77 49.04 157 - LIHC, LGG, HNSC, BRCA, OV, UCEC, STAD, BLCA, PRAD, GBM, READ, LUAD, SKCM, COAD, LUSC
ERBB3 P21860 ERBB3 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 103-104 2 3.71e-09 0.0 31 10.4 298 STAD READ, BLCA, BRCA, CESC, COAD, UCEC, STAD
KMT2C_ENST00000355193 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 773-845 73 4.66e-09 100.0 67 8.0 837 LUAD BRCA, UCEC, LIHC, LGG, HNSC, READ, BLCA, LUSC, COAD, KIRC, STAD, SKCM, GBM, LUAD, PRAD, CESC
EP300 Q09472 EP300 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1372-1536 165 4.76e-09 11.52 70 20.9 335 - LUSC, STAD, SARC, OV, CESC, HNSC, BLCA, LUAD, BRCA, COAD, LIHC, UCEC
KRAS P01116 KRAS GTPase KRas chr12 Census, Compendium Yes 61-61 1 5.55e-09 0.0 45 5.71 788 - REO, LAML, COAD, OV, READ, UCEC, PAAD, LUAD, BLCA, STAD, THCA, KIRC, SKCM, COT, LUSC
EP400 Q96L91 EP400 E1A-binding protein p400 chr12 Not Cancer Driver No 2747-2751 5 6.23e-09 100.0 1 0.25 397 COAD, READ COAD, READ, STAD
CLIP1 P30622 CLIP1 CAP-Gly domain-containing linker protein 1 chr12 Census, Compendium Yes 1012-1017 6 6.80e-09 88.89 44 20.56 214 SKCM, BLCA LUAD, BRCA, SKCM, KIRC, PRAD, BLCA
PHETA1_ENST00000547838 Q8N4B1 PHETA1 Sesquipedalian-1 chr12 Not Cancer Driver No 133-135 3 7.81e-09 100.0 1 5.26 19 READ OV, READ
TSKS Q9UJT2 TSKS Testis-specific serine kinase substrate chr19 Not Cancer Driver No 257-263 7 1.01e-08 100.0 7 5.51 127 READ BRCA, LUAD, COAD, READ, UCEC, CESC, SARC
DSPP_ENST00000282478 Q9NZW4 DSPP Dentin sialophosphoprotein chr4 Not Cancer Driver No 1023-1142 120 1.03e-08 100.0 19 8.8 216 COAD, READ COAD, READ, BRCA, CESC, UCEC, KIRC
CREBBP Q92793 CREBBP CREB-binding protein chr16 Census, Compendium Yes 1404-1488 85 1.12e-08 2.35 56 13.49 415 - SKCM, CESC, BRCA, GBM, OV, COAD, LUSC, STAD, UCEC, LUAD, DLBC, HNSC, LGG, BLCA
ZNF429 Q86V71 ZNF429 Zinc finger protein 429 chr19 Census, Compendium Yes 663-674 12 1.23e-08 100.0 42 13.29 316 GBM LUAD, STAD, SKCM, HNSC, KIRC, GBM
DNAH6 Q9C0G6 DNAH6 Dynein axonemal heavy chain 6 chr2 Not Cancer Driver No 497-664 168 1.42e-08 100.0 55 17.08 322 SKCM BRCA, OV, SARC, UCEC, PAAD, STAD, KIRC, HNSC, PRAD, LUSC, LIHC, SKCM, BLCA, LUAD
OPRD1 P41143 OPRD1 Delta-type opioid receptor chr1 Not Cancer Driver No 27-27 1 1.52e-08 100.0 48 40.68 118 COAD, READ COAD, READ
MEX3C Q5U5Q3 MEX3C RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 182-184 3 1.56e-08 100.0 0 0.0 54 READ COAD, UCEC, READ
AMY1A P0DUB6 AMY1A Alpha-amylase 1A chr1 Not Cancer Driver No 298-364 67 2.09e-08 0.0 20 100.0 20 - LUAD, GBM, STAD, SKCM, KIRC, BRCA, CESC, LUSC, PRAD, UCEC, COAD, BLCA, HNSC
PCBP1 Q15365 PCBP1 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 100-102 3 2.13e-08 0.0 22 33.85 65 COAD, READ THCA, LIHC, COAD, READ
POTEB2 H3BUK9 POTEB2 POTE ankyrin domain family member B2 chr15 Not Cancer Driver No 82-129 48 2.40e-08 14.58 36 55.38 65 SKCM READ, LGG, BLCA, GBM, SKCM, KIRC, LUSC, LUAD, UCEC
ZNF844 Q08AG5 ZNF844 Zinc finger protein 844 chr19 Not Cancer Driver No 487-523 37 2.61e-08 100.0 35 30.43 115 SKCM BRCA, GBM, LUAD, UCEC, LGG, PRAD, SKCM, KIRC
KRTAP4-11 Q9BYQ6 KRTAP4-11 Keratin-associated protein 4-11 chr17 Not Cancer Driver No 35-161 127 2.95e-08 100.0 121 92.37 131 - LIHC, STAD, KIRC, LUSC, HNSC, GBM, SKCM, LGG, LUAD, BRCA, COAD, CESC, OV, READ, PRAD, UCEC, BLCA
BOP1 Q14137 BOP1 Ribosome biogenesis protein BOP1 chr8 Not Cancer Driver No 37-93 57 3.58e-08 100.0 18 90.0 20 - COAD, BRCA, LIHC, BLCA, GBM, STAD, SKCM, UCEC, LUSC, LUAD
CFC1 P0CG37 CFC1 Cryptic protein chr2 Not Cancer Driver No 33-80 48 3.84e-08 100.0 25 100.0 25 LUAD LUAD, LIHC, SKCM, STAD, LUSC, UCEC, GBM, BLCA
DENND4B O75064 DENND4B DENN domain-containing protein 4B chr1 Not Cancer Driver No 907-910 4 3.87e-08 100.0 3 1.49 201 READ, COAD READ, OV, UCEC, COAD
CCND1 P24385 CCND1 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 280-293 14 4.15e-08 64.29 21 38.18 55 UCEC BLCA, HNSC, UCEC, CESC, COAD
MAPK1_ENST00000398822 P28482 MAPK1 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 321-322 2 4.71e-08 0.0 21 33.87 62 CESC, HNSC BLCA, CESC, UCEC, LUSC, HNSC
CTAGE6 Q86UF2 CTAGE6 cTAGE family member 6 chr7 Not Cancer Driver No 376-480 105 4.84e-08 0.0 51 57.95 88 SKCM CESC, LUSC, STAD, UCEC, BRCA, SKCM, LUAD, OV, HNSC
CDKN2A_ENST00000304494 P42771 CDKN2A Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 76-88 13 5.29e-08 61.54 53 31.93 166 - HNSC, LIHC, SKCM, BLCA, CESC, OV, LUSC, LUAD, STAD, COAD, BRCA, PAAD
UBXN11_ENST00000374221 Q5T124 UBXN11 UBX domain-containing protein 11 chr1 Not Cancer Driver No 486-504 19 5.70e-08 100.0 17 22.67 75 OV, COAD BRCA, OV, BLCA, READ, UCEC, COAD
NTSR2 O95665 NTSR2 Neurotensin receptor type 2 chr2 Not Cancer Driver No 54-54 1 5.94e-08 0.0 44 46.32 95 READ, COAD READ, COAD
MEF2A_ENST00000354410 Q02078 MEF2A Myocyte-specific enhancer factor 2A chr15 Not Cancer Driver No 417-422 6 6.05e-08 100.0 1 1.61 62 READ BRCA, COAD, READ, REO
PRAMEF20 Q5VT98 PRAMEF20 PRAME family member 20 chr1 Not Cancer Driver No 38-94 57 6.30e-08 8.77 27 93.1 29 SKCM KIRC, LIHC, LUAD, OV, CESC, SARC, STAD, SKCM
HS3ST4 Q9Y661 HS3ST4 Heparan sulfate glucosamine 3-O-sulfotransferase 4 chr16 Not Cancer Driver No 286-393 108 6.77e-08 0.0 71 61.21 116 SKCM CESC, LUAD, COAD, LIHC, READ, STAD, UCEC, HNSC, LGG, BRCA, PAAD, LUSC, THCA, SKCM, BLCA, GBM
KRT15_ENST00000393976 P19012 KRT15 Keratin, type I cytoskeletal 15 chr17 Not Cancer Driver No 202-214 13 7.53e-08 0.0 28 29.17 96 - PAAD, READ, GBM, KIRC, LGG, LIHC, BRCA, BLCA, SARC, CESC, PRAD, UCEC, COAD, HNSC, SKCM
RAC1_ENST00000348035 P63000 RAC1 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 26-34 9 7.63e-08 44.44 31 46.97 66 SKCM LUSC, HNSC, UCEC, SARC, BLCA, SKCM
TMEM184A Q6ZMB5 TMEM184A Transmembrane protein 184A chr7 Not Cancer Driver No 386-398 13 7.84e-08 100.0 13 19.7 66 READ, COAD READ, SKCM, COAD, LUAD
KLF5 Q13887 KLF5 Krueppel-like factor 5 chr13 Compendium Yes 411-419 9 7.84e-08 0.0 24 31.17 77 LUSC, CESC, BLCA STAD, LUSC, SKCM, CESC, BLCA, LUAD
PCGF6 Q9BYE7 PCGF6 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 26-28 3 9.05e-08 100.0 2 6.9 29 READ READ, LUSC, COAD, KIRC
ANKRD36 A6QL64 ANKRD36 Ankyrin repeat domain-containing protein 36A chr2 Not Cancer Driver No 995-998 4 9.54e-08 100.0 22 11.4 193 KIRC PRAD, GBM, HNSC, LUAD, UCEC, CESC, KIRC, SKCM
PHRF1 Q9P1Y6 PHRF1 PHD and RING finger domain-containing protein 1 chr11 Not Cancer Driver No 1018-1030 13 9.73e-08 100.0 3 1.24 241 COAD OV, BRCA, COAD, LUSC, SKCM, UCEC, CESC
GIGYF2_ENST00000409547 Q6Y7W6 GIGYF2 GRB10-interacting GYF protein 2 chr2 Not Cancer Driver No 1209-1228 20 9.77e-08 100.0 4 2.26 177 COAD, READ BRCA, GBM, COAD, READ, STAD, UCEC, OV
HRNR Q86YZ3 HRNR Hornerin chr1 Not Cancer Driver No 1857-1999 143 9.99e-08 100.0 88 13.84 636 - LUAD, LAML, COAD, SKCM, STAD, CESC, READ, LUSC, LIHC, UCEC, LGG, BRCA, OV, KIRC, BLCA, SARC
BRAF P15056 BRAF Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 464-469 6 1.05e-07 50.0 43 5.44 791 SKCM, LUAD COAD, SKCM, LUSC, STAD, BLCA, LUAD, UCEC, PRAD, READ, HNSC
RSBN1L Q6PCB5 RSBN1L Lysine-specific demethylase RSBN1L chr7 Not Cancer Driver No 432-432 1 1.05e-07 0.0 21 19.81 106 UCEC, LUAD UCEC, BRCA, LUAD
VHL P40337 VHL von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 65-167 103 1.05e-07 100.0 110 77.46 142 KIRC BLCA, PRAD, KIRC, UCEC, LUAD, SKCM, LUSC
MAP2K1 Q02750 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 118-130 13 1.15e-07 0.0 32 34.04 94 SKCM UCEC, STAD, COAD, LUSC, LIHC, LUAD, READ, SKCM
HLA-G_ENST00000360323 P17693 HLA-G HLA class I histocompatibility antigen, alpha chain G chr6 Not Cancer Driver No 300-331 32 1.16e-07 21.88 37 39.36 94 GBM LUSC, SKCM, GBM, OV, COAD, UCEC
ZNF787 Q6DD87 ZNF787 Zinc finger protein 787 chr19 Not Cancer Driver No 366-369 4 1.19e-07 100.0 2 5.41 37 COAD, READ COAD, READ, OAD
HRNR Q86YZ3 HRNR Hornerin chr1 Not Cancer Driver No 2111-2215 105 1.31e-07 100.0 72 11.32 636 SKCM LAML, COAD, PRAD, DLBC, LUAD, HNSC, STAD, SKCM, CESC, LIHC, READ, LUSC, BRCA, UCEC, BLCA, GBM
PCF11 O94913 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 chr11 Not Cancer Driver No 579-599 21 1.31e-07 100.0 29 13.68 212 KIRC LAML, BLCA, COAD, PRAD, KIRC, CESC, STAD, SARC, LIHC, LUSC, SKCM, BRCA
ERBB2 P04626 ERBB2 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 767-777 11 1.39e-07 36.36 28 10.14 276 BLCA, BRCA BLCA, LUAD, COAD, BRCA, STAD, READ, CESC
IFITM3 Q01628 IFITM3 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 117-133 17 1.57e-07 5.88 36 51.43 70 GBM CESC, BRCA, GBM
NCOA3 Q9Y6Q9 NCOA3 Nuclear receptor coactivator 3 chr20 Not Cancer Driver No 1267-1285 19 1.78e-07 100.0 5 2.84 176 COAD, READ LUAD, COAD, SKCM, READ
MUC5AC P98088 MUC5AC Mucin-5AC chr11 Not Cancer Driver No 4643-4760 118 1.84e-07 100.0 39 15.98 244 SKCM HNSC, STAD, LUAD, GBM, CESC, UCEC, BRCA, LUSC, BLCA, SKCM, PRAD
TRIM49C P0CI26 TRIM49C Tripartite motif-containing protein 49C chr11 Compendium Yes 277-403 127 1.90e-07 42.19 66 61.11 108 - OV, PRAD, STAD, UCEC, LUAD, BRCA, LUSC, CESC, SKCM, COAD, KIRC, BLCA, LIHC
NOTCH1 P46531 NOTCH1 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 416-484 69 2.16e-07 73.91 46 12.64 364 HNSC LUSC, CESC, SKCM, HNSC, PAAD, STAD, LGG, LUAD
RHOA P61586 RHOA Transforming protein RhoA chr3 Census, Compendium Yes 17-76 60 2.40e-07 35.0 66 66.67 99 STAD HNSC, LUSC, SKCM, READ, UCEC, COAD, OV, COT, LUAD, PRAD, BLCA, STAD, PAAD, BRCA
AGAP6_ENST00000374056 Q5VW22 AGAP6 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6 chr10 Not Cancer Driver No 100-109 10 2.64e-07 100.0 25 22.52 111 UCEC PRAD, STAD, GBM, CESC, BLCA, UCEC
MYLK3 Q32MK0 MYLK3 Myosin light chain kinase 3 chr16 Not Cancer Driver No 708-716 9 2.68e-07 0.0 24 14.72 163 BLCA BLCA, LGG, SKCM
FKBP9_ENST00000242209 O95302 FKBP9 Peptidyl-prolyl cis-trans isomerase FKBP9 chr7 Census Yes 147-166 20 3.49e-07 0.0 31 19.87 156 GBM LUSC, BLCA, GBM, STAD
NPIPA5 E9PKD4 NPIPA5 Nuclear pore complex-interacting protein family member A5 chr16 Not Cancer Driver No 290-293 4 3.59e-07 100.0 17 47.22 36 PRAD GBM, SKCM, LGG, KIRC, HNSC, LUAD, PRAD
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 451-455 5 3.62e-07 0.0 30 1.79 1677 - LUSC, CESC, LGG, LUAD, BRCA, COAD, HNSC, BLCA, UCEC, GBM, STAD
C3orf70 A6NLC5 C3orf70 UPF0524 protein C3orf70 chr3 Not Cancer Driver No 6-9 4 4.12e-07 100.0 21 36.21 58 BLCA BRCA, CESC, LUSC, BLCA
SPANXA2 Q9NS26 SPANXA2 Sperm protein associated with the nucleus on the X chromosome A chrX Not Cancer Driver No 3-17 15 4.89e-07 100.0 17 100.0 17 GBM GBM
DCP1B Q8IZD4 DCP1B mRNA-decapping enzyme 1B chr12 Not Cancer Driver No 250-252 3 4.99e-07 100.0 19 23.17 82 UCEC SKCM, COAD, LGG, UCEC, BLCA, LAML, LUAD
NBPF20 P0DPF2 NBPF20 Neuroblastoma breakpoint family member 20 chr1 Not Cancer Driver No 3252-3273 22 5.13e-07 100.0 16 59.26 27 KIRC, UCEC BRCA, KIRC, CESC, PRAD, LUAD, UCEC, SKCM, BLCA
POM121_ENST00000434423 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 chr7 Not Cancer Driver No 1014-1090 77 5.77e-07 100.0 27 16.88 160 BRCA OV, BRCA, SKCM, HNSC, SARC, UCEC, LUSC, CESC, KIRC, LUAD, COAD, LIHC
CIC Q96RK0 CIC Protein capicua homolog chr19 Census, Compendium Yes 939-939 1 6.18e-07 100.0 20 7.25 276 BLCA BLCA
RIN3 Q8TB24 RIN3 Ras and Rab interactor 3 chr14 Not Cancer Driver No 965-980 16 6.57e-07 70.59 2 1.42 141 COAD, READ COAD, UCEC, SKCM, READ, STAD, REO
CEBPA P49715 CEBPA CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 280-319 40 6.80e-07 0.0 10 83.33 12 LAML BLCA, STAD, COAD, SKCM, CESC, LAML
KRTAP9-1 A8MXZ3 KRTAP9-1 Keratin-associated protein 9-1 chr17 Not Cancer Driver No 152-153 2 6.94e-07 100.0 11 68.75 16 READ, BRCA COAD, READ, BRCA
KIAA1211 Q6ZU35 CRACD Capping protein-inhibiting regulator of actin dynamics chr4 Not Cancer Driver No 308-308 1 7.09e-07 0.0 1 0.4 250 READ, COAD READ, UCEC, COAD
IRF2BPL Q9H1B7 IRF2BPL Probable E3 ubiquitin-protein ligase IRF2BPL chr14 Not Cancer Driver No 126-127 2 7.53e-07 100.0 0 0.0 61 COAD, READ COAD, READ, REO
IDH2 P48735 IDH2 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 140-140 1 7.75e-07 0.0 19 25.33 75 LAML HNSC, LAML
PTH2 Q96A98 PTH2 Tuberoinfundibular peptide of 39 residues chr19 Not Cancer Driver No 22-22 1 8.05e-07 0.0 13 61.9 21 PRAD BLCA, PRAD, LUAD, UCEC, LGG, BRCA
MN1 Q10571 MN1 Transcriptional activator MN1 chr22 Census Yes 549-551 3 8.27e-07 0.0 1 0.67 149 READ, COAD UCEC, BRCA, READ, COAD, OAD
FAM155A B1AL88 NALF1 NALCN channel auxiliary factor 1 chr13 Not Cancer Driver No 69-86 18 8.40e-07 33.33 7 5.79 121 - LUAD, BRCA, THCA, COAD, READ, STAD, SKCM, LGG, BLCA, REO
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 418-420 3 8.57e-07 0.0 33 1.97 1677 UCEC STAD, BRCA, COAD, READ, UCEC, HNSC, BLCA, LUSC, CESC, LGG, PRAD
KRTAP1-5 Q9BYS1 KRTAP1-5 Keratin-associated protein 1-5 chr17 Not Cancer Driver No 88-91 4 8.62e-07 100.0 21 42.0 50 LGG, PRAD STAD, KIRC, LUSC, LGG, SKCM, UCEC, PRAD, LUAD
ANKRD20A8P Q5CZ79 ANKRD20A8P Ankyrin repeat domain-containing protein 20B chr2 Not Cancer Driver No 42-54 13 9.65e-07 0.0 29 17.16 169 - COAD, STAD, SKCM, HNSC, LGG, LUSC, KIRC, PRAD, LUAD
RXRA P19793 RXRA Retinoic acid receptor RXR-alpha chr9 Compendium Yes 426-427 2 1.04e-06 0.0 18 19.35 93 BLCA HNSC, SARC, LIHC, BLCA, PAAD
FOXA1 P55317 FOXA1 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 247-266 20 1.16e-06 80.0 24 23.76 101 BRCA, PRAD BRCA, PRAD, LUSC, SKCM
ATG2A Q2TAZ0 ATG2A Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1530-1534 5 1.17e-06 0.0 19 8.15 233 BLCA GBM, BLCA
POTEC B2RU33 POTEC POTE ankyrin domain family member C chr18 Not Cancer Driver No 477-477 1 1.27e-06 100.0 19 6.76 281 - LUAD, UCEC, PRAD, KIRC, SKCM, GBM
EGFR P00533 EGFR Epidermal growth factor receptor chr7 Census, Compendium Yes 852-866 15 1.28e-06 100.0 34 7.62 446 LUAD LUAD, UCEC, LUSC, STAD, GBM
BAIAP2L2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 chr22 Not Cancer Driver No 399-409 11 1.32e-06 100.0 5 11.63 43 COAD, READ KIRC, OV, UCEC, HNSC, COAD, READ
MYO15A_ENST00000647165 Q9UKN7 MYO15A Unconventional myosin-XV chr17 Not Cancer Driver No 265-402 138 1.35e-06 100.0 56 11.69 479 SKCM LUAD, SARC, LUSC, SKCM, PRAD, BRCA, LGG, HNSC, STAD, CESC, BLCA, UCEC
ELOA3C A0A087WVK4 ELOA3CP Elongin A3 family member C, pseudogene (Fragment) chr18 Not Cancer Driver No 213-243 31 1.46e-06 100.0 17 80.95 21 - STAD, CESC, PRAD, COAD, SARC, SKCM, LUSC
ASTN2_ENST00000313400 O75129 ASTN2 Astrotactin-2 chr9 Not Cancer Driver No 210-326 117 1.80e-06 80.34 72 20.57 350 - OV, LUSC, SKCM, COAD, PAAD, BLCA, GBM, HNSC, LUAD, UCEC, READ, KIRC, STAD
ATP9B O43861 ATP9B Probable phospholipid-transporting ATPase IIB chr18 Not Cancer Driver No 682-682 1 1.82e-06 0.0 18 12.33 146 BLCA BLCA
FNDC1 Q4ZHG4 FNDC1 Fibronectin type III domain-containing protein 1 chr6 Not Cancer Driver No 606-727 122 1.90e-06 100.0 69 16.87 409 - LUSC, UCEC, COAD, LUAD, BLCA, LGG, READ, LIHC, HNSC, THCA, SKCM, GBM, OV, STAD, LAML, PRAD, BRCA, CESC
INKA1 Q96EL1 INKA1 PAK4-inhibitor INKA1 chr3 Not Cancer Driver No 239-239 1 1.91e-06 100.0 16 40.0 40 BLCA COAD, BLCA
ERCC2 P18074 ERCC2 General transcription and DNA repair factor IIH helicase subunit XPD chr19 Census, Compendium Yes 312-312 1 1.93e-06 100.0 40 23.12 173 READ, COAD READ, COAD
PIK3CA P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 38-39 2 2.11e-06 0.0 32 1.91 1677 UCEC READ, KIRC, UCEC, GBM, STAD, LIHC, LUSC, CESC
TMEM247 A6NEH6 TMEM247 Transmembrane protein 247 chr2 Not Cancer Driver No 127-156 30 2.14e-06 22.58 28 80.0 35 COAD, BRCA OV, COAD, BRCA, LIHC, READ, UCEC
MB21D2 Q8IYB1 MB21D2 Nucleotidyltransferase MB21D2 chr3 Census, Compendium Yes 307-317 11 2.21e-06 0.0 24 24.49 98 LUSC LUSC, BLCA, BRCA, LUAD, READ, HNSC, UCEC, CESC
HBG2 P69892 HBG2 Hemoglobin subunit gamma-2 chr11 Not Cancer Driver No 60-118 59 2.34e-06 0.0 54 83.08 65 SKCM HNSC, GBM, BRCA, LUSC, SARC, SKCM, LUAD, PRAD, LIHC, LGG, STAD
KLHL30 Q0D2K2 KLHL30 Kelch-like protein 30 chr2 Not Cancer Driver No 211-213 3 2.34e-06 0.0 35 36.46 96 READ, COAD SKCM, READ, COAD
CASZ1 Q86V15 CASZ1 Zinc finger protein castor homolog 1 chr1 Compendium Yes 1678-1725 48 2.40e-06 100.0 9 3.75 240 READ, UCEC CESC, READ, LUAD, DLBC, COAD, UCEC, STAD
ABCA7 Q8IZY2 ABCA7 Phospholipid-transporting ATPase ABCA7 chr19 Not Cancer Driver No 2045-2045 1 2.53e-06 0.0 36 12.68 284 COAD, READ COAD, READ
FAM153B_ENST00000253490 P0C7A2 FAM153B Protein FAM153B chr5 Not Cancer Driver No 194-251 58 2.57e-06 100.0 32 55.17 58 - PRAD, GBM, THCA, KIRC, LUSC, OV, SKCM, UCEC, LUAD, PAAD, KICH, CESC, BLCA, READ, BRCA
HSPA8_ENST00000532636 P11142 HSPA8 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 199-280 82 2.82e-06 0.0 49 32.89 149 GBM CESC, LUAD, LUSC, GBM, PRAD, SKCM, BLCA, BRCA
FLT3 P36888 FLT3 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 835-843 9 2.87e-06 11.11 22 10.68 206 LAML LAML, STAD, GBM, SKCM
DLGAP2_ENST00000421627 Q9P1A6 DLGAP2 Disks large-associated protein 2 chr8 Not Cancer Driver No 299-385 87 2.87e-06 100.0 59 24.69 239 - BRCA, STAD, LUAD, KIRC, UCEC, COAD, HNSC, LUSC, PRAD, SKCM, BLCA, THCA, READ
BCAS4 Q8TDM0 BCAS4 Breast carcinoma-amplified sequence 4 chr20 Not Cancer Driver No 56-56 1 2.92e-06 100.0 30 56.6 53 COAD READ, COAD
P4HTM_ENST00000383729 Q9NXG6 P4HTM Transmembrane prolyl 4-hydroxylase chr3 Not Cancer Driver No 304-317 14 2.95e-06 0.0 22 28.95 76 BLCA STAD, LUAD, BLCA, UCEC, OV
ZNF683 Q8IZ20 ZNF683 Tissue-resident T-cell transcription regulator protein ZNF683 chr1 Not Cancer Driver No 243-250 8 3.13e-06 100.0 3 2.83 106 LAML COAD, READ, OV, LGG, LAML
MUC3A Q02505 MUC3A Mucin-3A chr7 Not Cancer Driver No 2752-2811 60 3.57e-06 100.0 35 15.77 222 SKCM OV, LUSC, BLCA, LGG, SKCM, BRCA, LUAD, CESC
SBK2_ENST00000344158 P0C263 SBK2 Serine/threonine-protein kinase SBK2 chr19 Not Cancer Driver No 298-305 8 3.76e-06 0.0 40 46.51 86 COAD, READ PRAD, COAD, READ
ZNF837 Q96EG3 ZNF837 Zinc finger protein 837 chr19 Not Cancer Driver No 242-242 1 4.07e-06 100.0 28 52.83 53 COAD, READ COAD, READ
EIF1AX P47813 EIF1AX Eukaryotic translation initiation factor 1A, X-chromosomal chrX Census, Compendium Yes 2-15 14 4.59e-06 100.0 23 58.97 39 - LGG, HNSC, UCEC, OV, THCA, LUAD, SKCM, CESC
ONECUT2 O95948 ONECUT2 One cut domain family member 2 chr18 Not Cancer Driver No 410-496 87 4.60e-06 38.64 37 47.44 78 - UCEC, LUSC, KIRC, BLCA, SKCM, OV, BRCA, GBM, CESC, LUAD, HNSC, COAD, STAD
PRAMEF14 Q5SWL7 PRAMEF14 PRAME family member 14 chr1 Not Cancer Driver No 386-446 61 4.77e-06 100.0 24 77.42 31 SKCM OV, CESC, HNSC, BLCA, LUSC, COAD, STAD, SKCM, BRCA, LIHC
NBPF14_ENST00000621066 Q5TI25 NBPF14 Neuroblastoma breakpoint family member 14 chr1 Not Cancer Driver No 222-271 50 4.81e-06 100.0 13 100.0 13 STAD, LUAD STAD, BRCA, SKCM, LUAD, COAD, CESC
EBPL Q9BY08 EBPL Emopamil-binding protein-like chr13 Not Cancer Driver No 186-197 12 5.07e-06 0.0 21 51.22 41 UCEC, KIRC UCEC, KIRC, GBM, BRCA, CESC, LGG, READ
CARD10_ENST00000251973 Q9BWT7 CARD10 Caspase recruitment domain-containing protein 10 chr22 Not Cancer Driver No 272-279 8 5.36e-06 100.0 2 2.06 97 UCEC READ, LUSC, COAD, UCEC, OV
FAM171B Q6P995 FAM171B Protein FAM171B chr2 Not Cancer Driver No 55-56 2 5.41e-06 0.0 0 0.0 156 READ, COAD BRCA, READ, OV, COAD, OAD
SKIDA1 Q1XH10 SKIDA1 SKI/DACH domain-containing protein 1 chr10 Not Cancer Driver No 427-427 1 5.41e-06 100.0 0 0.0 97 COAD, READ UCEC, COAD, OV, READ
RARS2 Q5T160 RARS2 Probable arginine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 6-6 1 5.43e-06 0.0 16 18.18 88 BLCA, BRCA BLCA, PAAD, LUAD, KIRC, LUSC, BRCA, CESC
ETNK2_ENST00000367202 Q9NVF9 ETNK2 Ethanolamine kinase 2 chr1 Not Cancer Driver No 10-10 1 5.45e-06 100.0 34 53.97 63 READ, COAD GBM, READ, COAD
GAL3ST3_ENST00000527878 Q96A11 GAL3ST3 Galactose-3-O-sulfotransferase 3 chr11 Not Cancer Driver No 171-281 111 5.92e-06 0.0 52 63.41 82 - LUSC, BLCA, READ, STAD, LGG, LIHC, SKCM, UCEC, CESC, KIRC, OV, PAAD, GBM, LUAD, COAD
UNCX A6NJT0 UNCX Homeobox protein unc-4 homolog chr7 Not Cancer Driver No 130-187 58 6.61e-06 43.1 20 71.43 28 - COT, CESC, STAD, BRCA, LGG, BLCA, SKCM, LUAD, HNSC
PRAMEF7_ENST00000330881 Q5VXH5 PRAMEF7 PRAME family member 7 chr1 Not Cancer Driver No 297-373 77 6.92e-06 0.0 33 70.21 47 SKCM LUAD, LIHC, UCEC, LUSC, LGG, STAD, PRAD, SKCM, SARC, COAD, BRCA, HNSC
ATM_ENST00000452508 Q13315 ATM Serine-protein kinase ATM chr11 Census, Compendium Yes 335-341 7 8.17e-06 100.0 25 5.27 474 - PRAD, COAD, READ, BLCA, LUAD, HNSC, UCEC, SKCM, SARC, LIHC, PAAD, STAD
OTUD4_ENST00000447906 Q01804 OTUD4 OTU domain-containing protein 4 chr4 Not Cancer Driver No 970-975 6 8.61e-06 100.0 19 12.84 148 THCA THCA, SKCM, COAD, LGG, STAD, BLCA, UCEC, GBM, PRAD
PCDHA7 Q9UN72 PCDHA7 Protocadherin alpha-7 chr5 Not Cancer Driver No 345-356 12 8.70e-06 33.33 26 7.81 333 READ, COAD READ, SKCM, COAD, REO, LGG
FGFR3_ENST00000440486 P22607 FGFR3 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 370-380 11 8.88e-06 36.36 23 13.14 175 BLCA HNSC, BLCA, LUSC, KIRC, STAD
GEMIN2 O14893 GEMIN2 Gem-associated protein 2 chr14 Not Cancer Driver No 221-223 3 9.12e-06 0.0 26 50.98 51 BLCA BLCA
LATS2 Q9NRM7 LATS2 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 322-324 3 9.14e-06 100.0 33 15.71 210 COAD, READ SKCM, COAD, READ
ZNF845 Q96IR2 ZNF845 Zinc finger protein 845 chr19 Not Cancer Driver No 925-925 1 9.56e-06 0.0 32 14.75 217 LGG, PRAD LGG, LUAD, KIRC, PRAD, SKCM, GBM
ZNF219 Q9P2Y4 ZNF219 Zinc finger protein 219 chr14 Not Cancer Driver No 233-239 7 1.07e-05 100.0 1 2.22 45 COAD, READ COAD, CESC, READ
RUNX1_ENST00000344691 Q01196 RUNX1 Runt-related transcription factor 1 chr21 Census, Compendium Yes 107-186 80 1.09e-05 10.0 37 45.68 81 LAML SKCM, BRCA, LUAD, COAD, OV, LUSC, LAML, UCEC, BLCA
FSIP2 Q5CZC0 FSIP2 Fibrous sheath-interacting protein 2 chr2 Not Cancer Driver No 6407-6534 128 1.10e-05 100.0 40 10.03 399 - BLCA, STAD, LGG, READ, KIRC, LIHC, CESC, UCEC, LUSC, LUAD, BRCA, SKCM
PPP2R1A P30153 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 248-260 13 1.13e-05 0.0 27 15.08 179 UCEC OV, LUAD, LIHC, COAD, UCEC, SKCM, CESC
CTCF P49711 CTCF Transcriptional repressor CTCF chr16 Census, Compendium Yes 328-394 67 1.13e-05 0.0 43 28.48 151 UCEC BRCA, LIHC, LUAD, UCEC, READ, SKCM, PRAD, BLCA, HNSC, STAD
ARHGEF33_ENST00000398800 A8MVX0 ARHGEF33 Rho guanine nucleotide exchange factor 33 chr2 Not Cancer Driver No 576-586 11 1.13e-05 100.0 27 39.13 69 READ, COAD BRCA, READ, COAD
TGFBR2_ENST00000295754 P37173 TGFBR2 TGF-beta receptor type-2 chr3 Census, Compendium Yes 518-530 13 1.15e-05 0.0 23 21.7 106 HNSC STAD, PAAD, READ, HNSC, SKCM, COAD, KIRC, LUAD, CESC, LUSC, GBM
HLA-DQB2 P05538 HLA-DQB2 HLA class II histocompatibility antigen, DQ beta 2 chain chr6 Not Cancer Driver No 247-250 4 1.16e-05 0.0 17 30.91 55 LGG BLCA, PRAD, KIRC, LGG, SKCM, BRCA
NBPF10 Q6P3W6 NBPF10 Neuroblastoma breakpoint family member 10 chr1 Not Cancer Driver No 995-1000 6 1.16e-05 100.0 16 5.93 270 KIRC, BRCA KIRC, PAAD, BLCA, COAD, BRCA, STAD, UCEC, CESC
TCAF1 Q9Y4C2 TCAF1 TRPM8 channel-associated factor 1 chr7 Not Cancer Driver No 52-124 73 1.27e-05 0.0 24 55.81 43 SKCM, LUAD COAD, GBM, SKCM, UCEC, LUAD, HNSC, BRCA
FMN2 Q9NZ56 FMN2 Formin-2 chr1 Not Cancer Driver No 927-1016 90 1.31e-05 100.0 77 12.24 629 - UCEC, PAAD, LGG, HNSC, DLBC, BRCA, LUAD, LUSC, OV, KIRC, PRAD, READ, SKCM, COAD, BLCA
KRTAP5-5 Q701N2 KRTAP5-5 Keratin-associated protein 5-5 chr11 Not Cancer Driver No 17-61 45 1.31e-05 100.0 19 30.16 63 READ LUSC, COAD, LUAD, STAD, UCEC, BLCA, CESC, KIRC, READ, OV, PRAD
ADAD2_ENST00000315906 Q8NCV1 ADAD2 Adenosine deaminase domain-containing protein 2 chr16 Not Cancer Driver No 44-48 5 1.37e-05 100.0 18 20.0 90 READ, COAD LUSC, READ, COAD, SKCM
NINL Q9Y2I6 NINL Ninein-like protein chr20 Not Cancer Driver No 954-961 8 1.38e-05 100.0 5 2.16 232 LAML GBM, UCEC, COAD, LAML, READ, STAD, SKCM
ANKLE1 A0A499FJM0 ANKLE1 Ankyrin repeat and LEM domain-containing protein 1 chr19 Not Cancer Driver No 148-148 1 1.45e-05 100.0 30 22.73 132 READ, COAD REO, READ, COAD, OAD
KHDC4 Q7Z7F0 KHDC4 KH homology domain-containing protein 4 chr1 Not Cancer Driver No 444-454 11 1.51e-05 100.0 18 19.35 93 SKCM HNSC, LUSC, LGG, PRAD, GBM, LUAD, KIRC, SKCM
GPX1_ENST00000620890 P07203 GPX1 Glutathione peroxidase 1 chr3 Not Cancer Driver No 76-84 9 1.58e-05 100.0 16 42.11 38 - PRAD, LIHC, LGG, KIRC, SKCM, HNSC, BLCA, LUAD
ROBO3 Q96MS0 ROBO3 Roundabout homolog 3 chr11 Not Cancer Driver No 1367-1371 5 1.61e-05 100.0 1 0.48 208 COAD READ, UCEC, COAD
ZNF384 Q8TF68 ZNF384 Zinc finger protein 384 chr12 Census Yes 511-524 14 1.63e-05 100.0 1 1.56 64 UCEC CESC, UCEC, OV, READ, COAD
HLA-A_ENST00000376809 P04439 HLA-A HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 75-80 6 1.63e-05 0.0 18 13.33 135 - BRCA, LUAD, KIRC, LGG, HNSC, CESC, PRAD, SKCM, LUSC, UCEC
AC104389.5 A0A2R8Y7X9 AC104389.5 GLOBIN domain-containing protein chr11 Not Cancer Driver No 60-118 59 1.65e-05 100.0 54 72.97 74 SKCM GBM, HNSC, LIHC, LGG, LUSC, PRAD, STAD, SKCM, SARC, BRCA, LUAD
GOLGA6L4 A6NEF3 GOLGA6L4 Golgin subfamily A member 6-like protein 4 chr15 Not Cancer Driver No 437-449 13 1.69e-05 0.0 11 68.75 16 LUAD, UCEC LAML, LUAD, PRAD, UCEC, PAAD
NBPF19 A0A087WUL8 NBPF19 Neuroblastoma breakpoint family member 19 chr1 Not Cancer Driver No 3789-3831 43 1.69e-05 100.0 12 66.67 18 LUSC UCEC, LUSC, BRCA, LIHC, LUAD, OV, BLCA
CNTNAP3B Q96NU0 CNTNAP3B Contactin-associated protein-like 3B chr9 Not Cancer Driver No 255-341 87 1.78e-05 26.97 40 29.85 134 LUAD HNSC, OV, STAD, CESC, LGG, LIHC, LUAD, PRAD, KIRC, UCEC, BLCA, LUSC, SKCM, READ
SETD2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 chr3 Census, Compendium Yes 1603-1668 66 1.82e-05 0.0 34 10.56 322 KIRC COAD, OV, KIRC, CESC, SKCM, HNSC, LUAD, BRCA, UCEC, LUSC, LGG, BLCA
FIGNL2_ENST00000564840 A6NMB9 FIGNL2 Fidgetin-like protein 2 chr12 Not Cancer Driver No 366-366 1 1.86e-05 100.0 26 78.79 33 COAD, READ COAD, READ
CTSA_ENST00000372459 P10619 CTSA Lysosomal protective protein chr20 Not Cancer Driver No 19-32 14 1.88e-05 64.29 3 5.08 59 READ SKCM, UCEC, LUSC, BRCA, OV, COAD, READ
CAP1_ENST00000372805 Q01518 CAP1 Adenylyl cyclase-associated protein 1 chr1 Not Cancer Driver No 306-313 8 1.90e-05 100.0 19 26.76 71 BLCA OV, SKCM, UCEC, BLCA
EPHA10 Q5JZY3 EPHA10 Ephrin type-A receptor 10 chr1 Not Cancer Driver No 132-157 26 1.96e-05 42.31 26 14.77 176 - STAD, LGG, LUAD, COAD, SKCM, LIHC, GBM, OV, READ, LAML, UCEC, LUSC, CESC
CYP2D7 A0A087X1C5 CYP2D7 Putative cytochrome P450 2D7 chr22 Not Cancer Driver No 116-123 8 2.01e-05 0.0 17 22.97 74 PRAD CESC, HNSC, SKCM, GBM, LUAD, LGG, PRAD, KIRC
CCR5 P51681 CCR5 C-C chemokine receptor type 5 chr3 Not Cancer Driver No 56-130 75 2.05e-05 0.0 50 46.73 107 GBM SKCM, STAD, BLCA, LUAD, GBM
CLIP1 P30622 CLIP1 CAP-Gly domain-containing linker protein 1 chr12 Census, Compendium Yes 270-271 2 2.09e-05 0.0 29 13.55 214 BLCA LIHC, BLCA
GLTPD2 A6NH11 GLTPD2 Glycolipid transfer protein domain-containing protein 2 chr17 Not Cancer Driver No 209-209 1 2.15e-05 0.0 30 56.6 53 COAD, READ COAD, READ
MYOM1 P52179 MYOM1 Myomesin-1 chr18 Not Cancer Driver No 205-216 12 2.16e-05 100.0 22 7.61 289 COAD COAD, READ, UCEC, BLCA, STAD, SKCM, PRAD, LUSC
PRAMEF11 O60813 PRAMEF11 PRAME family member 11 chr1 Not Cancer Driver No 120-132 13 2.18e-05 100.0 26 16.46 158 LUAD, SKCM LUAD, BRCA, PRAD, KIRC, GBM, STAD, HNSC, UCEC, SKCM
EFCAB6 Q5THR3 EFCAB6 EF-hand calcium-binding domain-containing protein 6 chr22 Not Cancer Driver No 379-380 2 2.26e-05 100.0 15 5.62 267 SKCM, PRAD LGG, SKCM, GBM, PRAD, LUAD, CESC
SLC16A14 Q7RTX9 SLC16A14 Monocarboxylate transporter 14 chr2 Not Cancer Driver No 85-98 14 2.28e-05 0.0 21 16.41 128 BLCA BLCA, HNSC, OV, KIRC, UCEC
POTEC B2RU33 POTEC POTE ankyrin domain family member C chr18 Not Cancer Driver No 47-69 23 2.30e-05 100.0 40 14.23 281 LUSC LUSC, STAD, HNSC, LUAD, PAAD, SARC, BLCA, PRAD, KIRC, OV, COAD, SKCM, GBM
NBPF10 Q6P3W6 NBPF10 Neuroblastoma breakpoint family member 10 chr1 Not Cancer Driver No 99-102 4 2.41e-05 100.0 15 5.56 270 SKCM CESC, LGG, UCEC, PRAD, SKCM, LUAD, BLCA, KIRC
PGM3_ENST00000513973 O95394 PGM3 Phosphoacetylglucosamine mutase chr6 Not Cancer Driver No 156-158 3 2.42e-05 0.0 14 17.72 79 BLCA SKCM, BLCA
ERBB2 P04626 ERBB2 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 841-842 2 2.45e-05 0.0 16 5.8 276 UCEC READ, COAD, PAAD, STAD, UCEC, BRCA, BLCA
OR2T5 Q6IEZ7 OR2T5 Olfactory receptor 2T5 chr1 Not Cancer Driver No 16-77 62 2.51e-05 0.0 26 70.27 37 SKCM COAD, GBM, SKCM, LUSC, READ, STAD, LUAD, OV, HNSC, BRCA
SF3B1 O75533 SF3B1 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 693-700 8 2.61e-05 0.0 18 7.35 245 BRCA SARC, LAML, KIRC, BRCA, BLCA, SKCM, PRAD
SWI5 Q1ZZU3 SWI5 DNA repair protein SWI5 homolog chr9 Not Cancer Driver No 3-62 60 2.61e-05 100.0 33 73.33 45 SKCM UCEC, COAD, CESC, LIHC, LUSC, HNSC, SKCM, LUAD, BRCA, STAD, BLCA, READ
ZNF91 Q05481 ZNF91 Zinc finger protein 91 chr19 Not Cancer Driver No 261-363 103 2.80e-05 3.88 66 20.62 320 - STAD, THCA, LUAD, CESC, SKCM, KIRC, LUSC, UCEC, PRAD, LGG, HNSC, READ, COAD, BLCA
NPIPB4 C9JG80 NPIPB4 Nuclear pore complex-interacting protein family member B4 chr16 Not Cancer Driver No 130-158 29 2.90e-05 55.17 16 47.06 34 SKCM LUSC, UCEC, LUAD, PRAD, STAD, SARC, SKCM
MAATS1 Q7Z4T9 CFAP91 Cilia- and flagella-associated protein 91 chr3 Not Cancer Driver No 604-618 15 2.92e-05 0.0 22 13.58 162 - LUSC, SKCM, CESC, UCEC, STAD, BRCA, LGG, READ, SARC, HNSC, GBM, LIHC, LUAD
CNOT9_ENST00000273064 Q92600 CNOT9 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 131-131 1 2.96e-05 0.0 14 33.33 42 SKCM SKCM
FRG1 Q14331 FRG1 Protein FRG1 chr4 Not Cancer Driver No 126-141 16 3.06e-05 0.0 24 32.0 75 BLCA KIRC, LUAD, UCEC, THCA, GBM, BRCA, SKCM, LIHC, BLCA
GOLGA6L6 A8MZA4 GOLGA6L6 Golgin subfamily A member 6-like protein 6 chr15 Not Cancer Driver No 395-406 12 3.14e-05 83.33 2 5.56 36 BRCA BRCA, CESC
TTC24_ENST00000368237 A2A3L6 TTC24 Tetratricopeptide repeat protein 24 chr1 Not Cancer Driver No 280-320 41 3.30e-05 0.0 22 37.93 58 - READ, LUSC, CESC, BRCA, LUAD, UCEC, KIRC, COAD, STAD, SKCM
DIABLO Q9NR28 DIABLO Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 182-187 6 3.36e-05 0.0 16 25.0 64 GBM, UCEC OV, GBM, BRCA, UCEC, LIHC
KLHDC7A Q5VTJ3 KLHDC7A Kelch domain-containing protein 7A chr1 Not Cancer Driver No 629-640 12 3.36e-05 0.0 20 11.36 176 SKCM SKCM, UCEC, STAD, HNSC, LIHC, PRAD, CESC
CT47B1 P0C2W7 CT47B1 Cancer/testis antigen 47B chrX Not Cancer Driver No 235-245 11 3.37e-05 100.0 7 5.15 136 OV, COAD, READ HNSC, OV, COAD, KIRC, LUAD, READ, SKCM, CESC
KIR3DL2 P43630 KIR3DL2 Killer cell immunoglobulin-like receptor 3DL2 chr19 Not Cancer Driver No 355-418 64 3.61e-05 90.62 41 45.05 91 - SKCM, UCEC, STAD, HNSC, LUAD, LUSC, KIRC, BRCA, THCA, OV, BLCA, GBM
PRIM2 P49643 PRIM2 DNA primase large subunit chr6 Not Cancer Driver No 448-508 61 3.66e-05 83.61 54 30.0 180 - LUSC, LGG, LUAD, HNSC, BLCA, COAD, GBM, CESC, READ, SKCM
KLRG2 A4D1S0 KLRG2 Killer cell lectin-like receptor subfamily G member 2 chr7 Not Cancer Driver No 152-152 1 3.68e-05 100.0 30 41.67 72 READ, COAD READ, COAD
MAX P61244 MAX Protein max chr14 Census, Compendium Yes 60-60 1 3.68e-05 0.0 14 31.11 45 UCEC CESC, STAD, UCEC, LAML, LGG, READ, COAD
ZSCAN18_ENST00000240727 Q8TBC5 ZSCAN18 Zinc finger and SCAN domain-containing protein 18 chr19 Not Cancer Driver No 164-168 5 3.76e-05 100.0 17 14.05 121 BLCA BLCA, SKCM
RRAS2 P62070 RRAS2 Ras-related protein R-Ras2 chr11 Compendium Yes 70-79 10 3.77e-05 30.0 15 51.72 29 UCEC PRAD, STAD, HNSC, LUAD, UCEC, LUSC
EEF1A1 P68104 EEF1A1 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 429-434 6 3.82e-05 0.0 17 15.45 110 LIHC KIRC, SARC, LIHC, HNSC, BLCA, GBM
FRG2B Q96QU4 FRG2B Protein FRG2-like-1 chr10 Not Cancer Driver No 2-28 27 3.84e-05 100.0 29 36.71 79 SKCM UCEC, STAD, HNSC, SARC, LAML, LUAD, LUSC, BLCA, SKCM
LRRC43 Q8N309 LRRC43 Leucine-rich repeat-containing protein 43 chr12 Not Cancer Driver No 519-530 12 3.96e-05 100.0 19 13.29 143 COAD KIRC, BRCA, GBM, COAD, READ
RHOXF2B P0C7M4 RHOXF2B Rhox homeobox family member 2B chrX Not Cancer Driver No 74-117 44 3.98e-05 100.0 20 80.0 25 LUAD DLBC, READ, HNSC, BRCA, LUSC, SKCM, LUAD, UCEC
SLCO6A1_ENST00000379807 Q86UG4 SLCO6A1 Solute carrier organic anion transporter family member 6A1 chr5 Not Cancer Driver No 2-71 70 4.04e-05 100.0 56 25.0 224 SKCM BRCA, COAD, HNSC, CESC, UCEC, GBM, LGG, SKCM, LUSC, STAD, BLCA, LUAD
DDX11 Q96FC9 DDX11 ATP-dependent DNA helicase DDX11 chr12 Not Cancer Driver No 166-167 2 4.10e-05 100.0 14 8.75 160 LUAD, SKCM KIRC, READ, CESC, LUAD, SKCM, LUSC
ZMIZ1 Q9ULJ6 ZMIZ1 Zinc finger MIZ domain-containing protein 1 chr10 Not Cancer Driver No 287-306 20 4.12e-05 100.0 15 10.14 148 BLCA LUAD, BRCA, GBM, LUSC, STAD, OV, UCEC, BLCA, SKCM, LGG
LATS2 Q9NRM7 LATS2 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 363-363 1 4.15e-05 100.0 28 13.33 210 READ, COAD READ, OAD, COAD
MUC5B Q9HC84 MUC5B Mucin-5B chr11 Not Cancer Driver No 4303-4408 106 4.21e-05 100.0 50 5.29 946 SKCM UCEC, STAD, BRCA, LUAD, BLCA, HNSC, CESC, OV, LUSC, LAML, THCA, READ, LGG, SKCM
MYADML2 A6NDP7 MYADML2 Myeloid-associated differentiation marker-like protein 2 chr17 Not Cancer Driver No 112-116 5 4.33e-05 0.0 22 64.71 34 COAD, READ COAD, READ
FKBP9_ENST00000242209 O95302 FKBP9 Peptidyl-prolyl cis-trans isomerase FKBP9 chr7 Census Yes 107-110 4 4.37e-05 0.0 17 10.9 156 GBM LUAD, GBM
OR5H6 Q8NGV6 OR5H6 Olfactory receptor 5H6 chr3 Not Cancer Driver No 123-126 4 4.38e-05 0.0 9 6.38 141 COAD, LAML COAD, READ, LUSC, LAML
POLRMT O00411 POLRMT DNA-directed RNA polymerase, mitochondrial chr19 Not Cancer Driver No 555-555 1 4.38e-05 0.0 32 15.09 212 READ, COAD READ, COAD
DOT1L Q8TEK3 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 Compendium Yes 1386-1386 1 4.44e-05 100.0 28 14.36 195 COAD, READ COAD, REO, READ
MAU2 Q9Y6X3 MAU2 MAU2 chromatid cohesion factor homolog chr19 Not Cancer Driver No 13-21 9 4.70e-05 100.0 1 1.47 68 READ READ
KCNE5 Q9UJ90 KCNE5 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 chrX Not Cancer Driver No 23-38 16 4.71e-05 100.0 20 57.14 35 BLCA SKCM, UCEC, BLCA, BRCA
RSPH10B_ENST00000337579 P0C881 RSPH10B Radial spoke head 10 homolog B chr7 Not Cancer Driver No 529-577 49 4.82e-05 0.0 22 29.33 75 - LUSC, UCEC, OV, KIRC, BRCA, READ, SKCM, COAD, CESC, LIHC, HNSC, STAD
ARID2 Q68CP9 ARID2 AT-rich interactive domain-containing protein 2 chr12 Census, Compendium Yes 268-327 60 5.00e-05 13.33 37 13.6 272 SKCM READ, HNSC, BRCA, BLCA, LUAD, UCEC, KIRC, COAD, LIHC, PRAD, SKCM, STAD
MYCN P04198 MYCN N-myc proto-oncogene protein chr2 Census, Compendium Yes 40-49 10 5.03e-05 100.0 16 22.54 71 UCEC, SKCM BLCA, STAD, UCEC, GBM, OV, SKCM
SOX3 P41225 SOX3 Transcription factor SOX-3 chrX Not Cancer Driver No 117-192 76 5.19e-05 27.63 29 46.03 63 - SARC, LUSC, LUAD, SKCM, HNSC, LIHC, UCEC, COAD, LGG, GBM, BRCA, STAD, BLCA
TCF15 Q12870 TCF15 Transcription factor 15 chr20 Not Cancer Driver No 114-114 1 5.30e-05 0.0 12 63.16 19 COAD, READ COAD, READ
KMT2C_ENST00000355193 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 964-977 14 5.37e-05 100.0 21 2.51 837 - SKCM, LUAD, GBM, CESC, DLBC, UCEC, BRCA, HNSC, BLCA, LUSC
CRNKL1 Q9BZJ0 CRNKL1 Crooked neck-like protein 1 chr20 Census, Compendium Yes 81-145 65 5.38e-05 100.0 34 26.98 126 SKCM SKCM, LUAD, UCEC, BRCA, CESC, HNSC, LUSC
VEZF1 Q14119 VEZF1 Vascular endothelial zinc finger 1 chr17 Not Cancer Driver No 350-354 5 5.41e-05 80.0 0 0.0 56 BRCA, COAD BRCA, COAD
CFAP47 Q6ZTR5 CFAP47 Cilia- and flagella-associated protein 47 chrX Not Cancer Driver No 365-478 114 5.47e-05 100.0 44 9.98 441 SKCM LUAD, READ, KIRC, PAAD, STAD, LIHC, COAD, LUSC, UCEC, SKCM, HNSC, BLCA, CESC, THCA
MED15 Q96RN5 MED15 Mediator of RNA polymerase II transcription subunit 15 chr22 Not Cancer Driver No 138-292 155 5.53e-05 77.42 22 22.45 98 - GBM, LUSC, LUAD, STAD, UCEC, BRCA, BLCA, SKCM, READ, COAD, OV
CNGB3 Q9NQW8 CNGB3 Cyclic nucleotide-gated cation channel beta-3 chr8 Not Cancer Driver No 78-172 95 5.67e-05 83.16 56 22.49 249 SKCM LUAD, COAD, BLCA, THCA, BRCA, HNSC, LGG, STAD, READ, KIRC, LUSC, UCEC, LIHC, SKCM
GLT6D1 Q7Z4J2 GLT6D1 Putative glycosyltransferase 6 domain-containing protein 1 chr9 Not Cancer Driver No 53-67 15 5.72e-05 0.0 21 26.25 80 SKCM, BLCA LUAD, UCEC, READ, SKCM, BLCA, PRAD
PRPF8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1809-1889 81 5.77e-05 0.0 25 9.8 255 UCEC UCEC, PRAD, STAD, KIRC, BRCA, LUAD, READ, COAD, SKCM, CESC
NLRP5 P59047 NLRP5 NACHT, LRR and PYD domains-containing protein 5 chr19 Not Cancer Driver No 729-740 12 5.81e-05 0.0 23 6.13 375 SKCM LUSC, UCEC, BLCA, STAD, GBM, COAD, SKCM, LUAD
SLC9B1 Q4ZJI4 SLC9B1 Sodium/hydrogen exchanger 9B1 chr4 Not Cancer Driver No 449-501 53 5.86e-05 3.77 32 35.96 89 LUAD KIRC, STAD, SARC, BLCA, COAD, UCEC, LUSC, SKCM, LUAD
RPL14_ENST00000396203 P50914 RPL14 60S ribosomal protein L14 chr3 Not Cancer Driver No 149-159 11 5.89e-05 100.0 1 4.76 21 UCEC COAD, READ, OV, UCEC
CSMD3 Q7Z407 CSMD3 CUB and sushi domain-containing protein 3 chr8 Census Yes 2601-2601 1 5.92e-05 100.0 14 0.77 1816 GBM LUSC, GBM, COAD, OV
TRPM6 Q9BX84 TRPM6 Transient receptor potential cation channel subfamily M member 6 chr9 Not Cancer Driver No 870-876 7 5.95e-05 0.0 18 4.13 436 BLCA SKCM, BLCA, LUAD, CESC
CT45A6_ENST00000612878 P0DMU7 CT45A6 Cancer/testis antigen family 45 member A6 chrX Not Cancer Driver No 172-188 17 5.95e-05 0.0 14 100.0 14 - LUSC, BLCA, HNSC, STAD, UCEC, LUAD, CESC, SKCM
CHD4 Q14839 CHD4 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 969-975 7 5.97e-05 0.0 17 4.02 423 UCEC COAD, LAML, KIRC, UCEC, READ, OV, BRCA
TNS1 Q9HBL0 TNS1 Tensin-1 chr2 Not Cancer Driver No 650-661 12 6.09e-05 100.0 4 1.41 284 READ, BRCA UCEC, READ, PRAD, LGG, BRCA, LUSC
TTLL11 Q8NHH1 TTLL11 Tubulin polyglutamylase TTLL11 chr9 Not Cancer Driver No 160-163 4 6.55e-05 100.0 26 26.26 99 READ, COAD REO, OAD, READ, COAD
SLC27A5 Q9Y2P5 SLC27A5 Bile acyl-CoA synthetase chr19 Not Cancer Driver No 550-558 9 6.63e-05 0.0 18 16.36 110 SKCM STAD, LUAD, BLCA, SKCM
NASP P49321 NASP Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 372-375 4 6.74e-05 100.0 13 13.54 96 BLCA BRCA, BLCA, SKCM
CACNA1E_ENST00000621551 Q15878 CACNA1E Voltage-dependent R-type calcium channel subunit alpha-1E chr1 Not Cancer Driver No 1690-1701 12 6.79e-05 30.77 23 2.95 779 SKCM READ, LIHC, HNSC, STAD, CESC, COAD, LUAD, BRCA, SKCM, UCEC
POTEF A5A3E0 POTEF POTE ankyrin domain family member F chr2 Not Cancer Driver No 37-144 108 7.00e-05 81.82 61 22.51 271 - UCEC, HNSC, COAD, OV, LUAD, GBM, CESC, SKCM, LUSC, PAAD, PRAD, STAD
HCLS1 P14317 HCLS1 Hematopoietic lineage cell-specific protein chr3 Not Cancer Driver No 372-373 2 7.24e-05 100.0 2 1.87 107 COAD, READ LUAD, SKCM, COAD, READ
HRCT1 Q6UXD1 HRCT1 Histidine-rich carboxyl terminus protein 1 chr9 Not Cancer Driver No 92-106 15 7.28e-05 100.0 10 50.0 20 - HNSC, KIRC, SKCM, CESC, LUAD, PRAD, BLCA, GBM, REO, READ, COAD, UCEC
TCHH Q07283 TCHH Trichohyalin chr1 Not Cancer Driver No 486-501 16 7.74e-05 0.0 20 4.39 456 READ, COAD READ, UCEC, KIRC, CESC, COAD, DLBC
GOLGA6L1 Q8N7Z2 GOLGA6L1 Golgin subfamily A member 6-like protein 1 chr15 Not Cancer Driver No 75-102 28 7.77e-05 100.0 10 100.0 10 LUSC HNSC, SKCM, GBM, BLCA, STAD, LGG, LUSC
STK19 P49842 STK19 Serine/threonine-protein kinase 19 chr6 Not Cancer Driver No 88-97 10 7.78e-05 100.0 18 30.0 60 SKCM HNSC, SKCM
SF3B3 Q15393 SF3B3 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 128-130 3 8.58e-05 0.0 26 15.66 166 BLCA BLCA, COAD
CUL1_ENST00000602748 Q13616 CUL1 Cullin-1 chr7 Not Cancer Driver No 483-489 7 8.73e-05 0.0 16 10.6 151 BLCA LUSC, KIRC, CESC, BLCA, STAD, HNSC, UCEC, PAAD
FKBP9_ENST00000242209 O95302 FKBP9 Peptidyl-prolyl cis-trans isomerase FKBP9 chr7 Census Yes 417-417 1 8.86e-05 0.0 13 8.33 156 GBM SKCM, GBM
CLIP2 Q9UDT6 CLIP2 CAP-Gly domain-containing linker protein 2 chr7 Not Cancer Driver No 381-386 6 8.86e-05 0.0 16 9.82 163 BLCA BLCA, OV
DCAF12L2 Q5VW00 DCAF12L2 DDB1- and CUL4-associated factor 12-like protein 2 chrX Census, Compendium Yes 330-337 8 8.96e-05 12.5 22 9.65 228 - HNSC, BRCA, SKCM, OV, PRAD, STAD, READ, THCA, COAD, GBM, LUSC, LUAD, UCEC, LGG
CDC27_ENST00000066544 P30260 CDC27 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 273-274 2 9.02e-05 100.0 13 7.26 179 PRAD, COAD SKCM, BLCA, HNSC, PRAD, COAD
OR11H12 B2RN74 OR11H12 Olfactory receptor 11H12 chr14 Not Cancer Driver No 139-177 39 9.11e-05 0.0 40 30.08 133 SKCM KIRC, UCEC, THCA, HNSC, LIHC, SKCM, BRCA, STAD, GBM, LUSC, OV, LUAD
KIF19 Q2TAC6 KIF19 Kinesin-like protein KIF19 chr17 Not Cancer Driver No 804-813 10 9.19e-05 100.0 31 17.13 181 COAD, READ COAD, OV, LUSC, LUAD, READ
ADAM22 Q9P0K1 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 chr7 Not Cancer Driver No 81-85 5 9.33e-05 100.0 30 14.71 204 COAD, READ COAD, READ, LUSC
ANAPC1 Q9H1A4 ANAPC1 Anaphase-promoting complex subunit 1 chr2 Not Cancer Driver No 533-538 6 9.42e-05 100.0 13 6.28 207 - UCEC, LUSC, LUAD, CESC, GBM, KIRC, PRAD, SKCM
TRIM48 Q8IWZ4 TRIM48 E3 ubiquitin-protein ligase TRIM48 chr11 Not Cancer Driver No 185-195 11 9.58e-05 100.0 40 31.25 128 UCEC STAD, LUSC, UCEC, LUAD, HNSC, BRCA
MGAM_ENST00000475668 O43451 MGAM Maltase-glucoamylase chr7 Not Cancer Driver No 1091-1102 12 9.77e-05 100.0 20 2.8 715 SKCM HNSC, LUAD, SKCM, BRCA, COAD, UCEC
CDK4 P11802 CDK4 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 22-24 3 9.79e-05 0.0 12 23.08 52 LUAD, SKCM LUAD, SKCM
DNMT3A Q9Y6K1 DNMT3A DNA (cytosine-5)-methyltransferase 3A chr2 Census, Compendium Yes 878-882 5 9.92e-05 0.0 16 8.21 195 LAML BLCA, BRCA, LAML, LUSC, LUAD
MARCH11 A6NNE9 MARCHF11 E3 ubiquitin-protein ligase MARCHF11 chr5 Not Cancer Driver No 288-352 65 1.02e-04 33.85 35 44.3 79 SKCM, LUAD CESC, HNSC, KIRC, STAD, BLCA, LIHC, UCEC, OV, SKCM, LUAD, SARC, LUSC
NBPF10 Q6P3W6 NBPF10 Neuroblastoma breakpoint family member 10 chr1 Not Cancer Driver No 284-361 78 1.03e-04 100.0 32 11.85 270 UCEC LUSC, GBM, BRCA, SKCM, STAD, UCEC, HNSC, CESC, LUAD, COAD
RRAD P55042 RRAD GTP-binding protein RAD chr16 Not Cancer Driver No 269-284 16 1.03e-04 62.5 16 34.78 46 KIRC UCEC, KIRC, HNSC, READ, SKCM, STAD, PRAD, GBM, LGG, CESC
ERBB2 P04626 ERBB2 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 678-678 1 1.04e-04 0.0 14 5.07 276 STAD BLCA, STAD, UCEC, BRCA, COAD, PRAD
BSN Q9UPA5 BSN Protein bassoon chr3 Not Cancer Driver No 84-182 99 1.08e-04 100.0 36 6.73 535 SKCM LUSC, SKCM, BLCA, PRAD, BRCA, THCA, COAD, UCEC, READ, GBM, KIRC, PAAD
FAM124B Q9H5Z6 FAM124B Protein FAM124B chr2 Not Cancer Driver No 75-92 18 1.11e-04 11.11 18 26.09 69 - SKCM, LGG, LUSC, STAD, GBM, THCA, BLCA, LUAD, OV, UCEC, BRCA
NWD1_ENST00000552788 Q149M9 NWD1 NACHT domain- and WD repeat-containing protein 1 chr19 Not Cancer Driver No 205-212 8 1.11e-04 30.0 31 8.93 347 BLCA BLCA, SKCM
WDR66 Q8TBY9 CFAP251 Cilia- and flagella-associated protein 251 chr12 Not Cancer Driver No 57-66 10 1.11e-04 100.0 8 4.32 185 COAD LUAD, READ, COAD, BRCA, GBM, STAD, UCEC, LUSC, THCA
WIPI2 Q9Y4P8 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 323-324 2 1.14e-04 0.0 12 18.46 65 BLCA BLCA
MTOR P42345 MTOR Serine/threonine-protein kinase mTOR chr1 Census, Compendium Yes 2209-2216 8 1.15e-04 0.0 21 5.51 381 KIRC UCEC, COAD, READ, KIRC, LIHC, LUSC, GBM, BLCA, LGG
RAF1 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 257-264 8 1.16e-04 100.0 18 20.22 89 SKCM, LUAD SKCM, LIHC, STAD, READ, LUAD
MARCH1 Q8TCQ1 MARCHF1 E3 ubiquitin-protein ligase MARCHF1 chr4 Not Cancer Driver No 50-121 72 1.17e-04 37.5 37 56.92 65 LUAD COAD, LUAD, HNSC, BLCA, THCA, PRAD, SKCM, LUSC, UCEC, STAD
CA9 Q16790 CA9 Carbonic anhydrase 9 chr9 Not Cancer Driver No 83-96 14 1.18e-04 100.0 9 12.5 72 READ, COAD READ, SKCM, LUAD, STAD, KIRC, COAD, BLCA
FEZ2_ENST00000405912 Q9UHY8 FEZ2 Fasciculation and elongation protein zeta-2 chr2 Not Cancer Driver No 50-50 1 1.19e-04 100.0 22 44.9 49 READ, COAD READ, COAD
OGFR Q9NZT2 OGFR Opioid growth factor receptor chr20 Not Cancer Driver No 576-577 2 1.19e-04 100.0 24 27.91 86 COAD, READ COAD, READ
FKBP9_ENST00000242209 O95302 FKBP9 Peptidyl-prolyl cis-trans isomerase FKBP9 chr7 Census Yes 269-277 9 1.20e-04 0.0 19 12.18 156 GBM BLCA, BRCA, GBM, HNSC, COAD
MBD1_ENST00000591416 Q9UIS9 MBD1 Methyl-CpG-binding domain protein 1 chr18 Not Cancer Driver No 355-369 15 1.22e-04 0.0 9 7.83 115 BLCA UCEC, GBM, LUAD, BLCA, STAD, LGG, BRCA, LUSC
KAT8_ENST00000219797 Q9H7Z6 KAT8 Histone acetyltransferase KAT8 chr16 Not Cancer Driver No 85-169 85 1.23e-04 64.71 33 50.0 66 STAD SKCM, CESC, BLCA, STAD, OV, HNSC, LUSC, READ, KIRC, UCEC, BRCA
NAB2 Q15742 NAB2 NGFI-A-binding protein 2 chr12 Census Yes 208-208 1 1.23e-04 100.0 12 17.91 67 LGG, LUAD GBM, BLCA, PRAD, LGG, LUAD, SKCM
MESP2 Q0VG99 MESP2 Mesoderm posterior protein 2 chr15 Not Cancer Driver No 198-205 8 1.25e-04 100.0 0 0.0 35 READ READ
DLL3 Q9NYJ7 DLL3 Delta-like protein 3 chr19 Not Cancer Driver No 249-325 77 1.32e-04 35.06 30 40.54 74 - UCEC, READ, CESC, PRAD, LUSC, STAD, LUAD, BRCA, THCA, BLCA, SKCM
IGSF3_ENST00000369486 O75054 IGSF3 Immunoglobulin superfamily member 3 chr1 Not Cancer Driver No 1019-1021 3 1.34e-04 100.0 5 2.72 184 COAD COAD, SKCM, BLCA, PRAD, UCEC
MGAM2 Q2M2H8 MGAM2 Probable maltase-glucoamylase 2 chr7 Not Cancer Driver No 1500-1544 45 1.35e-04 0.0 17 27.42 62 SKCM LUAD, LUSC, LIHC, SKCM, READ, BRCA
HASPIN Q8TF76 HASPIN Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 82-82 1 1.36e-04 100.0 28 27.18 103 COAD, READ COAD, READ
SP5 Q6BEB4 SP5 Transcription factor Sp5 chr2 Not Cancer Driver No 75-75 1 1.36e-04 100.0 24 55.81 43 READ COAD, READ
FOXQ1 Q9C009 FOXQ1 Forkhead box protein Q1 chr6 Not Cancer Driver No 135-155 21 1.37e-04 0.0 12 54.55 22 BLCA HNSC, LUAD, SKCM, PAAD, LUSC, LGG, BLCA, STAD
FGF23 Q9GZV9 FGF23 Fibroblast growth factor 23 chr12 Not Cancer Driver No 163-211 49 1.44e-04 83.67 38 44.19 86 - BRCA, OV, SKCM, BLCA, COAD, LUSC, KIRC, GBM, HNSC, UCEC, READ, SARC, LUAD
RP1 P56715 RP1 Oxygen-regulated protein 1 chr8 Not Cancer Driver No 119-193 75 1.46e-04 49.33 58 7.82 742 - SKCM, LUAD, HNSC, UCEC, READ, COT, PRAD, BRCA, DLBC, COAD, STAD, LGG, GBM, BLCA, LIHC, LUSC
MUC5AC P98088 MUC5AC Mucin-5AC chr11 Not Cancer Driver No 4889-4950 62 1.48e-04 100.0 20 8.2 244 - PRAD, SKCM, LUSC, BLCA, UCEC, CESC, LGG, LUAD, STAD, HNSC
TAL1 P17542 TAL1 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 248-319 72 1.48e-04 100.0 30 55.56 54 SKCM LUAD, KIRC, SKCM, READ, GBM, CESC, HNSC, STAD, LUSC
NBPF10 Q6P3W6 NBPF10 Neuroblastoma breakpoint family member 10 chr1 Not Cancer Driver No 14-53 40 1.52e-04 100.0 22 8.15 270 - GBM, LUSC, SKCM, STAD, HNSC, KIRC, THCA, BLCA, LUAD, COAD
AC019117.3 A0A1B0GVI7 AC019117.3 Aryl hydrocarbon receptor (Fragment) chr7 Not Cancer Driver No 373-383 11 1.53e-04 100.0 17 14.17 120 BLCA LUSC, KIRC, LUAD, BLCA, LIHC
RHEB Q15382 RHEB GTP-binding protein Rheb chr7 Not Cancer Driver No 13-63 51 1.53e-04 0.0 23 76.67 30 - LUSC, KIRC, COAD, OV, LIHC, BRCA, UCEC, LUAD, STAD, BLCA, SKCM
ANKLE1 A0A499FJM0 ANKLE1 Ankyrin repeat and LEM domain-containing protein 1 chr19 Not Cancer Driver No 85-85 1 1.55e-04 100.0 26 19.7 132 COAD, READ COAD, READ
TCAF2_ENST00000441159 A6NFQ2 TCAF2 TRPM8 channel-associated factor 2 chr7 Not Cancer Driver No 305-375 71 1.58e-04 0.0 23 37.7 61 SKCM HNSC, READ, BRCA, COAD, LUSC, UCEC, SKCM, CESC, LUAD
GFRA2 O00451 GFRA2 GDNF family receptor alpha-2 chr8 Not Cancer Driver No 351-409 59 1.60e-04 86.67 27 43.55 62 - BRCA, SKCM, UCEC, LUSC, STAD, BLCA, HNSC, LUAD, PAAD, CESC, KIRC
AHR P35869 AHR Aryl hydrocarbon receptor chr7 Not Cancer Driver No 383-393 11 1.61e-04 9.09 17 13.08 130 BLCA LIHC, BLCA, KIRC, LUAD, LUSC
INAVA_ENST00000367342 Q3KP66 INAVA Innate immunity activator protein chr1 Not Cancer Driver No 538-538 1 1.63e-04 100.0 26 19.55 133 READ OAD, COAD, LUSC, READ
TCF7L2_ENST00000355995 Q9NQB0 TCF7L2 Transcription factor 7-like 2 chr10 Census, Compendium Yes 486-488 3 1.64e-04 0.0 15 12.3 122 COAD, READ COAD, READ, UCEC
ASAH2 Q9NR71 ASAH2 Neutral ceramidase chr10 Not Cancer Driver No 50-113 64 1.70e-04 76.92 26 36.11 72 SKCM READ, LUSC, LUAD, BRCA, SKCM, LIHC, HNSC, CESC
EGFLAM Q63HQ2 EGFLAM Pikachurin chr5 Not Cancer Driver No 195-275 81 1.74e-04 59.04 58 20.14 288 SKCM UCEC, LUAD, STAD, BLCA, CESC, HNSC, BRCA, LUSC, THCA, LIHC, KIRC, SKCM
PTEN P60484 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 165-178 14 1.74e-04 0.0 44 8.71 505 GBM, UCEC LUSC, COAD, GBM, LIHC, LGG, OV, UCEC, KIRC, PRAD, SKCM, STAD
KRTAP4-9 Q9BYQ8 KRTAP4-9 Keratin-associated protein 4-9 chr17 Not Cancer Driver No 15-22 8 1.75e-04 100.0 19 22.62 84 PRAD COAD, SKCM, PRAD, LUAD, UCEC, LUSC, BRCA, KIRC, GBM, LGG, BLCA
COL6A5 A8TX70 COL6A5 Collagen alpha-5(VI) chain chr3 Not Cancer Driver No 139-200 62 1.75e-04 0.0 30 9.8 306 SKCM LUAD, BLCA, SKCM, GBM, LUSC, BRCA, REO, KIRC, READ, STAD, OV, COAD
KIF2B Q8N4N8 KIF2B Kinesin-like protein KIF2B chr17 Not Cancer Driver No 86-188 103 1.76e-04 73.58 95 29.41 323 - KIRC, HNSC, LUSC, SKCM, LGG, GBM, OV, CESC, READ, DLBC, BLCA, LUAD, PRAD, UCEC, STAD, BRCA
HS3ST3A1 Q9Y663 HS3ST3A1 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 chr17 Not Cancer Driver No 203-270 68 1.78e-04 0.0 32 50.79 63 - LUSC, HNSC, KIRC, CESC, UCEC, SKCM, GBM, STAD, LGG, LUAD, OV, SARC, READ
UPF2_ENST00000357604 Q9HAU5 UPF2 Regulator of nonsense transcripts 2 chr10 Not Cancer Driver No 1030-1034 5 1.79e-04 100.0 15 9.93 151 UCEC, STAD UCEC, READ, SARC, HNSC, COAD, STAD
SCN7A_ENST00000409855 Q01118 SCN7A Sodium channel protein type 7 subunit alpha chr2 Not Cancer Driver No 169-227 59 1.83e-04 16.95 40 10.08 397 SKCM KIRC, GBM, READ, STAD, LUAD, LUSC, BRCA, SKCM, HNSC, PRAD, CESC
GPRIN2_ENST00000374314 O60269 GPRIN2 G protein-regulated inducer of neurite outgrowth 2 chr10 Not Cancer Driver No 241-241 1 1.84e-04 100.0 13 8.84 147 COAD, READ KIRC, COAD, BLCA, READ
RGPD4 Q7Z3J3 RGPD4 RanBP2-like and GRIP domain-containing protein 4 chr2 Not Cancer Driver No 1327-1428 102 1.84e-04 25.24 61 15.84 385 SKCM LUAD, STAD, LUSC, CESC, SKCM, BRCA, UCEC, THCA, KIRC
E2F4 Q16254 E2F4 Transcription factor E2F4 chr16 Not Cancer Driver No 315-320 6 1.85e-04 100.0 8 18.18 44 READ COAD, BRCA, GBM, KIRC, UCEC, READ
RYR3 Q15413 RYR3 Ryanodine receptor 3 chr15 Not Cancer Driver No 1902-1915 14 1.86e-04 100.0 18 1.65 1091 SKCM LUAD, UCEC, SKCM, PRAD, THCA, BLCA, KIRC
FKBP9_ENST00000242209 O95302 FKBP9 Peptidyl-prolyl cis-trans isomerase FKBP9 chr7 Census Yes 301-302 2 1.86e-04 0.0 13 8.33 156 GBM UCEC, GBM
FYCO1 Q9BQS8 FYCO1 FYVE and coiled-coil domain-containing protein 1 chr3 Not Cancer Driver No 557-557 1 1.87e-04 100.0 12 6.49 185 BLCA BLCA
GOLGA6L7 A0A1B0GV03 GOLGA6L7 Golgin subfamily A member 6-like protein 7 chr15 Not Cancer Driver No 37-52 16 1.95e-04 100.0 11 40.74 27 - LUSC, COAD, PAAD, UCEC, HNSC, LGG, PRAD
ZAR1L A6NP61 ZAR1L ZAR1-like protein chr13 Not Cancer Driver No 136-137 2 1.95e-04 100.0 19 50.0 38 READ, COAD READ, UCEC, COAD, REO
PCDHA6 Q9UN73 PCDHA6 Protocadherin alpha-6 chr5 Not Cancer Driver No 601-663 63 1.98e-04 9.38 53 15.54 341 - BRCA, UCEC, LUSC, BLCA, READ, LUAD, CESC, SKCM, LIHC, STAD, COAD, HNSC, PRAD, KIRC
DICER1 Q9UPY3 DICER1 Endoribonuclease Dicer chr14 Census, Compendium Yes 1801-1813 13 2.00e-04 38.46 16 5.99 267 UCEC STAD, THCA, CESC, COAD, SKCM, LUSC, GBM, UCEC
SF3B1 O75533 SF3B1 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 620-626 7 2.02e-04 0.0 15 6.12 245 SKCM BRCA, SKCM, BLCA, LUAD, LIHC, PRAD
APOBR Q0VD83 APOBR Apolipoprotein B receptor chr16 Not Cancer Driver No 353-369 17 2.04e-04 100.0 14 8.43 166 BRCA BRCA, READ, LIHC, CESC, OV, UCEC, COAD, LGG
EIF3C Q99613 EIF3C Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 296-339 44 2.06e-04 68.18 11 73.33 15 LUSC, STAD LUAD, UCEC, BRCA, LUSC, PRAD, STAD
FOXD4L5 Q5VV16 FOXD4L5 Forkhead box protein D4-like 5 chr9 Not Cancer Driver No 272-294 23 2.12e-04 100.0 19 28.36 67 - UCEC, GBM, SARC, READ, PRAD, LUAD, SKCM, HNSC, LUSC, STAD
PPP6C_ENST00000373547 O00743 PPP6C Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 259-270 12 2.13e-04 0.0 17 26.98 63 SKCM SKCM
TNC P24821 TNC Tenascin chr9 Census, Compendium Yes 945-950 6 2.16e-04 50.0 15 4.13 363 BLCA BRCA, BLCA
NCL P19338 NCL Nucleolin chr2 Not Cancer Driver No 249-264 16 2.17e-04 100.0 10 11.76 85 COAD, UCEC COAD, BRCA, OV, UCEC, LIHC, READ
LSR_ENST00000361790 Q86X29 LSR Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 510-519 10 2.19e-04 100.0 1 1.12 89 UCEC, COAD SKCM, UCEC, COAD
CHD4 Q14839 CHD4 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1155-1162 8 2.24e-04 12.5 16 3.78 423 UCEC UCEC, LUAD, STAD, BLCA, BRCA, READ
HSD17B1_ENST00000585807 P14061 HSD17B1 17-beta-hydroxysteroid dehydrogenase type 1 chr17 Not Cancer Driver No 313-313 1 2.26e-04 100.0 24 39.34 61 COAD, READ COAD, READ
LRRIQ3 A6PVS8 LRRIQ3 Leucine-rich repeat and IQ domain-containing protein 3 chr1 Not Cancer Driver No 379-422 44 2.28e-04 97.83 40 18.1 221 SKCM KIRC, LUAD, REO, BRCA, PRAD, SKCM, STAD, OV, LUSC, BLCA, UCEC
TDRD10 Q5VZ19 TDRD10 Tudor domain-containing protein 10 chr1 Not Cancer Driver No 190-196 7 2.38e-04 0.0 14 16.09 87 GBM GBM, LGG, BRCA, OV, STAD, LAML, SKCM, LUAD
EGFR P00533 EGFR Epidermal growth factor receptor chr7 Census, Compendium Yes 767-774 8 2.39e-04 100.0 12 2.69 446 GBM, LUAD COAD, GBM, OV, LGG, LIHC, BRCA, LUAD
GTF2I P78347 GTF2I General transcription factor II-I chr7 Compendium Yes 437-453 17 2.44e-04 82.35 14 18.92 74 UCEC, BLCA UCEC, LUAD, BLCA, BRCA
NXF2B Q9GZY0 NXF2B Nuclear RNA export factor 2 chrX Not Cancer Driver No 193-242 50 2.46e-04 0.0 22 41.51 53 - LGG, COAD, HNSC, STAD, SKCM, LUAD, UCEC, BLCA, LUSC
CNBD1 Q8NA66 CNBD1 Cyclic nucleotide-binding domain-containing protein 1 chr8 Census Yes 393-401 9 2.47e-04 0.0 19 11.88 160 STAD BRCA, STAD, COAD, LUSC, BLCA, SKCM
OBSCN_ENST00000422127 Q5VST9 OBSCN Obscurin chr1 Not Cancer Driver No 1269-1276 8 2.47e-04 100.0 15 1.2 1252 BLCA BLCA, STAD, BRCA
ZNF429 Q86V71 ZNF429 Zinc finger protein 429 chr19 Census, Compendium Yes 419-437 19 2.49e-04 0.0 29 9.18 316 GBM GBM, SKCM
TMEM132C Q8N3T6 TMEM132C Transmembrane protein 132C chr12 Not Cancer Driver No 140-213 74 2.51e-04 18.42 31 25.0 124 - BRCA, KIRC, CESC, LGG, HNSC, SKCM, LUSC, UCEC, LIHC, STAD, LUAD, BLCA
MME_ENST00000492661 P08473 MME Neprilysin chr3 Not Cancer Driver No 271-296 26 2.53e-04 0.0 25 13.23 189 SKCM LUSC, KIRC, BLCA, COAD, UCEC, READ, SKCM, OAD, STAD
GCNA Q96QF7 GCNA Germ cell nuclear acidic protein chrX Not Cancer Driver No 234-298 65 2.54e-04 100.0 42 26.92 156 - BLCA, KIRC, LUAD, STAD, UCEC, HNSC, OV, LUSC, SKCM, LGG, SARC, GBM, CESC, COAD
ARL16 Q0P5N6 ARL16 ADP-ribosylation factor-like protein 16 chr17 Not Cancer Driver No 2-16 15 2.54e-04 100.0 17 58.62 29 SKCM READ, LUSC, COAD, SKCM, BLCA, LUAD
SMAD6 O43541 SMAD6 Mothers against decapentaplegic homolog 6 chr15 Not Cancer Driver No 383-440 58 2.55e-04 6.78 18 47.37 38 - BRCA, UCEC, STAD, COAD, KIRC, SKCM, LGG, PRAD, BLCA, LUAD
MUC16 Q8WXI7 MUC16 Mucin-16 chr19 Census Yes 5116-5119 4 2.56e-04 100.0 17 0.4 4204 SKCM SKCM, HNSC
TTN_ENST00000615779 Q8WZ42 TTN Titin chr2 Not Cancer Driver No 2962-2968 7 2.58e-04 100.0 27 0.34 7986 BLCA CESC, BLCA, LUAD
HIST1H2BH Q93079 H2BC9 Histone H2B type 1-H chr6 Not Cancer Driver No 68-77 10 2.60e-04 0.0 18 42.86 42 - LUSC, UCEC, HNSC, LUAD, STAD, BLCA, SKCM, BRCA, OV
USP36_ENST00000312010 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36 chr17 Not Cancer Driver No 951-967 17 2.64e-04 100.0 5 3.18 157 UCEC SKCM, UCEC, COAD, BRCA, OV, HNSC, LUSC
DNAH6 Q9C0G6 DNAH6 Dynein axonemal heavy chain 6 chr2 Not Cancer Driver No 716-768 53 2.69e-04 100.0 19 5.9 322 SKCM LUAD, GBM, BLCA, SKCM, CESC, STAD, HNSC, THCA, BRCA, UCEC
PRPF19 Q9UMS4 PRPF19 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 284-287 4 2.74e-04 0.0 11 15.49 71 LUAD SKCM, LUAD, BRCA
KMT2D O14686 KMT2D Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 5154-5236 83 2.80e-04 100.0 34 4.36 779 - PRAD, LUSC, LIHC, BRCA, SKCM, HNSC, BLCA, OV, STAD, UCEC, LUAD, SARC
CCDC9 Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 chr19 Not Cancer Driver No 215-215 1 2.81e-04 100.0 22 26.83 82 COAD, READ COAD, READ
ZNF429 Q86V71 ZNF429 Zinc finger protein 429 chr19 Census, Compendium Yes 392-409 18 2.83e-04 77.78 29 9.18 316 GBM GBM, READ, LUSC, BRCA
C9orf43_ENST00000374165 Q8TAL5 C9orf43 Uncharacterized protein C9orf43 chr9 Not Cancer Driver No 295-304 10 2.85e-04 100.0 6 8.82 68 BRCA UCEC, BRCA, OV, COAD, STAD
HOXB13 Q92826 HOXB13 Homeobox protein Hox-B13 chr17 Not Cancer Driver No 202-226 25 2.86e-04 64.0 21 33.87 62 - LUSC, LAML, GBM, READ, LUAD, STAD, UCEC, PRAD, SKCM, BRCA
PDYN P01213 PDYN Proenkephalin-B chr20 Not Cancer Driver No 202-216 15 2.96e-04 100.0 26 20.97 124 - LUSC, SKCM, GBM, HNSC, LUAD, OV, UCEC, KIRC, READ, COAD, STAD
GFRA1 P56159 GFRA1 GDNF family receptor alpha-1 chr10 Not Cancer Driver No 167-239 73 3.00e-04 0.0 43 35.83 120 - SKCM, GBM, LUSC, UCEC, CESC, STAD, OV, HNSC, READ, BLCA, LUAD
AOC2 O75106 AOC2 Retina-specific copper amine oxidase chr17 Not Cancer Driver No 270-279 10 3.07e-04 0.0 14 12.07 116 GBM SKCM, GBM, OV, COAD, HNSC
ERICH6 Q7L0X2 ERICH6 Glutamate-rich protein 6 chr3 Not Cancer Driver No 44-56 13 3.13e-04 100.0 9 7.5 120 READ COAD, UCEC, LUSC, READ, STAD
KRTAP4-6 Q9BYQ5 KRTAP4-6 Keratin-associated protein 4-6 chr17 Not Cancer Driver No 62-72 11 3.14e-04 100.0 16 17.98 89 READ, GBM READ, BLCA, BRCA, OV, STAD, GBM, LGG, SKCM
ARMC10 Q8N2F6 ARMC10 Armadillo repeat-containing protein 10 chr7 Not Cancer Driver No 271-328 58 3.14e-04 13.79 21 48.84 43 LUSC READ, LIHC, BLCA, COAD, LUAD, HNSC, GBM, STAD, SKCM, KIRC, OV, LUSC
HBG1 P69891 HBG1 Hemoglobin subunit gamma-1 chr11 Not Cancer Driver No 88-135 48 3.14e-04 0.0 20 86.96 23 SKCM LUSC, STAD, BLCA, LUAD, SARC, SKCM, COAD
APC P25054 APC Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1381-1442 62 3.19e-04 100.0 29 7.02 413 - BLCA, UCEC, STAD, OV, LUAD, SKCM, COAD, BRCA, READ, LUSC, GBM, THCA
SLC6A18 Q96N87 SLC6A18 Inactive sodium-dependent neutral amino acid transporter B(0)AT3 chr5 Not Cancer Driver No 206-212 7 3.19e-04 0.0 14 11.02 127 LUAD GBM, SKCM, LUAD
ZNF799 Q96GE5 ZNF799 Zinc finger protein 799 chr19 Not Cancer Driver No 589-589 1 3.21e-04 0.0 11 10.28 107 PRAD PRAD, SKCM, KIRC, GBM, LGG
CTAGE15 A4D2H0 CTAGE15 cTAGE family member 15 chr7 Not Cancer Driver No 425-485 61 3.23e-04 0.0 15 44.12 34 SKCM OV, STAD, LUAD, SKCM, LUSC, UCEC
METTL21C Q5VZV1 METTL21C Protein-lysine methyltransferase METTL21C chr13 Not Cancer Driver No 33-111 79 3.24e-04 20.99 34 60.71 56 SKCM LAML, COAD, UCEC, HNSC, SARC, BLCA, LIHC, LUSC, READ, SKCM, KIRC, STAD, LUAD, BRCA
KRTAP9-9 Q9BYP9-3 KRTAP9-9 Isoform 3 of Keratin-associated protein 9-9 chr17 Not Cancer Driver No 8-15 8 3.30e-04 100.0 3 10.71 28 COAD UCEC, LIHC, SKCM, OV, READ, COAD
CCAR1 Q8IX12 CCAR1 Cell division cycle and apoptosis regulator protein 1 chr10 Not Cancer Driver No 72-79 8 3.33e-04 100.0 14 9.59 146 BLCA STAD, OV, BLCA, BRCA
PIK3CB_ENST00000477593 P42338 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 Census, Compendium Yes 1046-1055 10 3.34e-04 0.0 15 10.0 150 BLCA, GBM BRCA, STAD, KIRC, UCEC, BLCA, GBM, SKCM
TINAG Q9UJW2 TINAG Tubulointerstitial nephritis antigen chr6 Not Cancer Driver No 187-191 5 3.38e-04 0.0 14 9.93 141 - LGG, UCEC, HNSC, BLCA, SKCM, CESC, LUAD, OV, LIHC
OR2A42_ENST00000391496 Q8NGT9 OR2A42 Olfactory receptor 2A1/2A42 chr7 Not Cancer Driver No 57-123 67 3.40e-04 0.0 18 78.26 23 SKCM COAD, BRCA, LUSC, SKCM, GBM, STAD, LUAD, UCEC
MYO18B_ENST00000335473 Q8IUG5 MYO18B Unconventional myosin-XVIIIb chr22 Not Cancer Driver No 2207-2267 61 3.48e-04 100.0 36 6.52 552 - THCA, LUAD, OV, SKCM, COAD, LIHC, GBM, BRCA, LUSC, UCEC
HIF1A_ENST00000337138 Q16665 HIF1A Hypoxia-inducible factor 1-alpha chr14 Census Yes 238-238 1 3.49e-04 0.0 11 7.59 145 GBM GBM
PYCR3_ENST00000495276 Q53H96 PYCR3 Pyrroline-5-carboxylate reductase 3 chr8 Not Cancer Driver No 245-256 12 3.55e-04 0.0 9 42.86 21 OV LUAD, CESC, BLCA, UCEC, BRCA, SKCM, OV
ADAMTS8 Q9UP79 ADAMTS8 A disintegrin and metalloproteinase with thrombospondin motifs 8 chr11 Not Cancer Driver No 473-550 78 3.60e-04 5.06 32 23.02 139 - GBM, OV, KIRC, BLCA, READ, SKCM, STAD, UCEC, COAD, HNSC, LUAD
MKRN3 Q13064 MKRN3 Probable E3 ubiquitin-protein ligase makorin-3 chr15 Not Cancer Driver No 116-137 22 3.65e-04 77.27 28 14.21 197 - KIRC, BLCA, SKCM, READ, LIHC, SARC, COAD, LUSC, STAD, HNSC, BRCA, LUAD, GBM
PCDH12 Q9NPG4 PCDH12 Protocadherin-12 chr5 Not Cancer Driver No 1169-1181 13 3.67e-04 100.0 5 3.16 158 READ, UCEC SKCM, READ, UCEC, CESC, OV
GRP P07492 GRP Gastrin-releasing peptide chr18 Not Cancer Driver No 4-4 1 3.69e-04 100.0 26 52.0 50 READ, COAD READ, COAD
DCC P43146 DCC Netrin receptor DCC chr18 Census, Compendium Yes 442-451 10 3.70e-04 0.0 23 4.32 532 - CESC, HNSC, SARC, STAD, KIRC, LUAD, OV, BLCA, LUSC, SKCM, UCEC, BRCA
AMY2A P04746 AMY2A Pancreatic alpha-amylase chr1 Not Cancer Driver No 25-95 71 3.72e-04 0.0 37 35.92 103 - BLCA, READ, HNSC, BRCA, LUSC, STAD, THCA, LUAD, LIHC, PAAD, UCEC, SKCM
CDKL5_ENST00000623535 O76039 CDKL5 Cyclin-dependent kinase-like 5 chrX Not Cancer Driver No 600-603 4 3.81e-04 100.0 11 6.59 167 GBM LUAD, GBM, SKCM
ACADS P16219 ACADS Short-chain specific acyl-CoA dehydrogenase, mitochondrial chr12 Not Cancer Driver No 325-331 7 3.82e-04 0.0 24 36.36 66 GBM LGG, KIRC, GBM, PRAD, STAD, REO, UCEC
SF1_ENST00000377390 Q15637 SF1 Splicing factor 1 chr11 Not Cancer Driver No 233-255 23 3.83e-04 26.09 19 17.27 110 - BLCA, UCEC, LUAD, COAD, OV, LIHC, CESC, BRCA, STAD, READ
CACNA1S Q13698 CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S chr1 Not Cancer Driver No 1444-1452 9 3.89e-04 0.0 12 3.02 398 BLCA BLCA, GBM, KIRC
DLGAP4_ENST00000339266 Q9Y2H0 DLGAP4 Disks large-associated protein 4 chr20 Not Cancer Driver No 5-45 41 3.89e-04 100.0 25 14.62 171 SKCM BRCA, COAD, READ, PAAD, HNSC, LUSC, LIHC, LUAD, STAD, CESC, SKCM
DMKN Q6E0U4 DMKN Dermokine chr19 Not Cancer Driver No 270-276 7 3.94e-04 100.0 10 10.64 94 COAD, OV COAD, KIRC, OV, READ
FANCD2_ENST00000383807 Q9BXW9 FANCD2 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 801-802 2 3.96e-04 0.0 11 6.21 177 BLCA BLCA, PRAD, BRCA, GBM, KIRC, LIHC
SPTA1_ENST00000368147 P02549 SPTA1 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 2009-2024 16 3.97e-04 0.0 36 3.35 1075 - UCEC, PAAD, HNSC, LAML, LUSC, LUAD, BLCA, SKCM, GBM, READ, KIRC, COAD, BRCA, PRAD, THCA
NOBOX O60393 NOBOX Homeobox protein NOBOX chr7 Not Cancer Driver No 272-322 51 3.98e-04 41.18 32 25.2 127 SKCM UCEC, PAAD, GBM, LUAD, LUSC, SKCM, KIRC, BRCA
PTPN11_ENST00000351677 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 69-82 14 3.98e-04 0.0 19 14.73 129 LAML, GBM LUSC, LAML, COAD, LGG, LUAD, GBM, READ
PTPN11_ENST00000351677 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 498-510 13 3.98e-04 0.0 17 13.18 129 GBM LUSC, LAML, COAD, SKCM, SARC, LGG, LUAD, GBM, STAD, READ
POTED Q86YR6 POTED POTE ankyrin domain family member D chr21 Not Cancer Driver No 67-151 85 3.98e-04 67.06 27 44.26 61 LUSC OV, LUAD, STAD, SKCM, LUSC, COAD, HNSC, CESC, GBM
MYO5B Q9ULV0 MYO5B Unconventional myosin-Vb chr18 Not Cancer Driver No 1701-1711 11 4.04e-04 0.0 14 5.2 269 SKCM, BLCA UCEC, SKCM, GBM, LUSC, KIRC, BLCA
ABCC10 Q5T3U5 ABCC10 ATP-binding cassette sub-family C member 10 chr6 Not Cancer Driver No 570-573 4 4.05e-04 0.0 11 5.7 193 GBM LGG, BRCA, LUSC, HNSC, KIRC, GBM, PRAD
SOS1_ENST00000402219 Q07889 SOS1 Son of sevenless homolog 1 chr2 Compendium Yes 233-233 1 4.06e-04 0.0 12 6.09 197 UCEC, LUAD LUSC, UCEC, LUAD
CIC Q96RK0 CIC Protein capicua homolog chr19 Census, Compendium Yes 1512-1515 4 4.09e-04 0.0 15 5.43 276 LGG BRCA, READ, LGG, BLCA
MMP25 Q9NPA2 MMP25 Matrix metalloproteinase-25 chr16 Not Cancer Driver No 151-228 78 4.12e-04 12.5 23 40.35 57 - SKCM, HNSC, LUAD, BRCA, OV, LAML, BLCA, STAD, KIRC, LUSC, PRAD
SRRM5 B3KS81 SRRM5 Serine/arginine repetitive matrix protein 5 chr19 Not Cancer Driver No 437-447 11 4.12e-04 100.0 12 20.34 59 UCEC KIRC, CESC, SARC, UCEC
KIF26B Q2KJY2 KIF26B Kinesin-like protein KIF26B chr1 Not Cancer Driver No 2023-2033 11 4.24e-04 0.0 14 3.76 372 - LIHC, BRCA, LUSC, HNSC, LGG, PRAD, SKCM, UCEC, GBM, OV
ERI1_ENST00000519292 Q8IV48 ERI1 3'-5' exoribonuclease 1 chr8 Not Cancer Driver No 16-16 1 4.26e-04 100.0 11 26.83 41 READ, COAD READ, COAD, REO
PODNL1 Q6PEZ8 PODNL1 Podocan-like protein 1 chr19 Not Cancer Driver No 145-150 6 4.26e-04 0.0 10 27.03 37 GBM LIHC, STAD, GBM
KDM4E B2RXH2 KDM4E Lysine-specific demethylase 4E chr11 Not Cancer Driver No 206-257 52 4.35e-04 0.0 19 44.19 43 LUAD, SKCM LUSC, HNSC, KIRC, STAD, LUAD, PRAD, SKCM
MN1 Q10571 MN1 Transcriptional activator MN1 chr22 Census Yes 1010-1050 41 4.35e-04 100.0 19 12.75 149 - GBM, COAD, STAD, LUAD, LUSC, HNSC, CESC, LIHC, UCEC, SKCM
TMEM200C_ENST00000383490 A6NKL6 TMEM200C Transmembrane protein 200C chr18 Not Cancer Driver No 12-44 33 4.38e-04 100.0 20 25.97 77 - STAD, SKCM, PAAD, HNSC, PRAD, BLCA, READ, UCEC, LUSC
ASPM Q8IZT6 ASPM Abnormal spindle-like microcephaly-associated protein chr1 Not Cancer Driver No 3444-3451 8 4.39e-04 100.0 14 2.51 557 GBM GBM, LUAD
GABRQ Q9UN88 GABRQ Gamma-aminobutyric acid receptor subunit theta chrX Not Cancer Driver No 479-490 12 4.39e-04 100.0 17 10.69 159 SKCM STAD, PRAD, OV, LUAD, HNSC, SKCM, COAD
DMXL2_ENST00000251076 Q8TDJ6 DMXL2 DmX-like protein 2 chr15 Not Cancer Driver No 2372-2372 1 4.43e-04 100.0 11 2.55 431 BLCA BLCA
OR5W2 Q8NH69 OR5W2 Olfactory receptor 5W2 chr11 Not Cancer Driver No 258-268 11 4.44e-04 18.18 22 14.29 154 LUAD OAD, LUSC, KIRC, OV, HNSC, CESC, LUAD, GBM, PRAD, SKCM, STAD, BRCA, READ, BLCA
ODF1 Q14990 ODF1 Outer dense fiber protein 1 chr8 Not Cancer Driver No 219-227 9 4.47e-04 100.0 4 7.69 52 COAD COAD, READ, KIRC
COL23A1 Q86Y22 COL23A1 Collagen alpha-1(XXIII) chain chr5 Not Cancer Driver No 131-213 83 4.53e-04 100.0 35 40.7 86 SKCM OV, HNSC, STAD, UCEC, GBM, BLCA, LUSC, SKCM, LUAD, DLBC, PRAD, BRCA
CYP4F2 P78329 CYP4F2 Cytochrome P450 4F2 chr19 Not Cancer Driver No 462-515 54 4.53e-04 0.0 34 24.11 141 - UCEC, LUSC, SKCM, KIRC, STAD, GBM, COAD, SARC, LUAD, BRCA, BLCA, HNSC, CESC
MUC4 Q99102 MUC4 Mucin-4 chr3 Census Yes 1001-1006 6 4.67e-04 100.0 14 1.36 1030 - PRAD, GBM, LGG, CESC, KIRC, LAML, UCEC, LUAD
PIEZO2 Q9H5I5 PIEZO2 Piezo-type mechanosensitive ion channel component 2 chr18 Not Cancer Driver No 2304-2357 54 4.72e-04 100.0 19 9.5 200 - STAD, LGG, UCEC, OV, LUSC, PAAD, PRAD, HNSC, LIHC, SKCM, GBM, BLCA
OBSCN_ENST00000422127 Q5VST9 OBSCN Obscurin chr1 Not Cancer Driver No 4516-4516 1 4.74e-04 100.0 24 1.92 1252 READ COAD, READ
ARHGEF5 Q12774 ARHGEF5 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 840-889 50 4.76e-04 100.0 24 14.12 170 SKCM GBM, COAD, SKCM, PRAD, KIRC, LAML, LUSC, BLCA, BRCA
EVA1B Q9NVM1 EVA1B Protein eva-1 homolog B chr1 Not Cancer Driver No 4-22 19 4.83e-04 42.11 13 72.22 18 SKCM BLCA, LUSC, SKCM, LGG, COAD, LIHC, LUAD
FRG2_ENST00000378763 Q64ET8 FRG2 Protein FRG2 chr4 Not Cancer Driver No 92-110 19 4.91e-04 100.0 10 71.43 14 SKCM, BLCA SKCM, COAD, LUAD, BLCA, STAD
POTEF A5A3E0 POTEF POTE ankyrin domain family member F chr2 Not Cancer Driver No 757-842 86 4.96e-04 1.16 40 14.76 271 LUAD LUSC, SKCM, CESC, STAD, READ, UCEC, BLCA, KIRC, LUAD, LIHC
HHIPL2 Q6UWX4 HHIPL2 HHIP-like protein 2 chr1 Not Cancer Driver No 278-294 17 4.98e-04 0.0 25 12.76 196 SKCM, LUAD SKCM, LUAD, PRAD, BLCA, GBM, STAD, LUSC
OR5B17 Q8NGF7 OR5B17 Olfactory receptor 5B17 chr11 Not Cancer Driver No 210-215 6 5.11e-04 0.0 13 15.85 82 SKCM LUAD, LUSC, STAD, SKCM, BLCA
RBM39 Q14498 RBM39 RNA-binding protein 39 chr20 Compendium Yes 344-354 11 5.11e-04 100.0 15 18.52 81 UCEC LUSC, UCEC, HNSC, BLCA, KIRC
ZNF787 Q6DD87 ZNF787 Zinc finger protein 787 chr19 Not Cancer Driver No 83-123 41 5.13e-04 2.44 17 45.95 37 - STAD, LIHC, SKCM, PAAD, HNSC, LUAD, UCEC, SARC, BLCA, LUSC, CESC
DENND5B_ENST00000389082 Q6ZUT9 DENND5B DENN domain-containing protein 5B chr12 Not Cancer Driver No 1197-1270 74 5.17e-04 0.0 29 16.76 173 - OV, LUAD, LUSC, KIRC, READ, BRCA, STAD, SKCM, BLCA, COAD, KICH, HNSC
BMP5 P22003 BMP5 Bone morphogenetic protein 5 chr6 Census Yes 313-335 23 5.26e-04 100.0 29 17.58 165 SKCM UCEC, STAD, PRAD, GBM, BLCA, SKCM, LUSC
ANKHD1 Q8IWZ3 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1258-1355 98 5.34e-04 0.0 24 8.19 293 - BRCA, SKCM, BLCA, KIRC, UCEC, LUAD, GBM, OV, CESC
POU4F2 Q12837 POU4F2 POU domain, class 4, transcription factor 2 chr4 Not Cancer Driver No 66-68 3 5.37e-04 100.0 1 0.75 133 UCEC, READ UCEC, COAD, CESC, READ
MUC6 Q6W4X9 MUC6 Mucin-6 chr11 Not Cancer Driver No 1733-1842 110 5.39e-04 100.0 40 9.78 409 BLCA OV, BRCA, CESC, DLBC, KIRC, SARC, COAD, SKCM, BLCA, LUSC, LUAD, LAML, STAD
DDHD1 Q8NEL9 DDHD1 Phospholipase DDHD1 chr14 Not Cancer Driver No 102-116 15 5.41e-04 100.0 3 2.5 120 COAD LUAD, READ, UCEC, COAD, BLCA
SOX17 Q9H6I2 SOX17 Transcription factor SOX-17 chr8 Compendium Yes 403-407 5 5.45e-04 100.0 13 15.85 82 UCEC UCEC, SARC, COAD
BBC3 Q96PG8 BBC3 Bcl-2-binding component 3, isoforms 3/4 chr19 Not Cancer Driver No 197-244 48 5.46e-04 100.0 15 75.0 20 - LUSC, UCEC, SKCM, BLCA, KIRC, LUAD, THCA, HNSC
NCOR1 O75376 NCOR1 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 146-164 19 5.46e-04 100.0 19 5.4 352 SKCM, LUSC SKCM, UCEC, STAD, BRCA, LUSC, LUAD, HNSC
FKBP8_ENST00000222308 Q14318 FKBP8 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 31-46 16 5.48e-04 100.0 7 9.86 71 READ SKCM, BLCA, BRCA, READ
FAM126B Q8IXS8 FAM126B Protein FAM126B chr2 Not Cancer Driver No 382-383 2 5.50e-04 100.0 10 18.87 53 GBM GBM, STAD, READ, LUSC, HNSC, LGG
PRSS2_ENST00000539842 P07478 PRSS2 Trypsin-2 chr7 Not Cancer Driver No 19-40 22 5.51e-04 27.27 19 37.25 51 SKCM SKCM, READ, PRAD, KIRC, STAD, LUSC, PAAD, HNSC, LUAD, BLCA
CHST9_ENST00000581714 Q7L1S5 CHST9 Carbohydrate sulfotransferase 9 chr18 Not Cancer Driver No 393-410 18 5.53e-04 0.0 17 18.89 90 OV, COAD LUSC, KIRC, OV, COAD, HNSC, SKCM
NMNAT2 Q9BZQ4 NMNAT2 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 chr1 Not Cancer Driver No 153-232 80 5.56e-04 47.5 30 55.56 54 - UCEC, KIRC, THCA, SKCM, STAD, OV, BRCA, LUSC, BLCA, GBM, COAD, LUAD
IFITM3 Q01628 IFITM3 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 70-76 7 5.63e-04 85.71 18 25.71 70 - PRAD, GBM, READ, LGG, BLCA, COAD, UCEC, KIRC, SKCM
NPEPPS P55786 NPEPPS Puromycin-sensitive aminopeptidase chr17 Compendium Yes 427-440 14 5.65e-04 0.0 14 13.73 102 BLCA LIHC, BLCA, PAAD, LUAD, BRCA, COAD, KIRC
PCDHGA3 Q9Y5H0 PCDHGA3 Protocadherin gamma-A3 chr5 Not Cancer Driver No 56-73 18 5.71e-04 27.78 21 7.69 273 - PRAD, KIRC, SKCM, HNSC, UCEC, LUSC, STAD, LUAD, COAD, BRCA, READ
AQP12A_ENST00000337801 Q8IXF9 AQP12A Aquaporin-12A chr2 Not Cancer Driver No 13-30 18 5.76e-04 0.0 18 40.0 45 BRCA, SKCM BRCA, GBM, STAD, LUAD, SKCM, CESC
ACSBG2_ENST00000591403 Q5FVE4 ACSBG2 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 Not Cancer Driver No 250-259 10 5.77e-04 0.0 13 10.66 122 UCEC, KIRC UCEC, KIRC, SKCM, CESC
CCDC141_ENST00000443758 Q6ZP82-2 CCDC141 Isoform 2 of Coiled-coil domain-containing protein 141 chr2 Not Cancer Driver No 832-853 22 5.85e-04 100.0 21 6.67 315 SKCM GBM, UCEC, HNSC, LUSC, COAD, SKCM, LUAD, BLCA
HAVCR1_ENST00000339252 Q96D42 HAVCR1 Hepatitis A virus cellular receptor 1 chr5 Not Cancer Driver No 140-163 24 5.89e-04 100.0 17 17.89 95 BLCA COAD, BLCA, OV, KIRC, STAD, LUAD, SKCM, UCEC, HNSC, GBM, LIHC
PNLIPRP2 P54317 PNLIPRP2 Pancreatic lipase-related protein 2 chr10 Not Cancer Driver No 107-152 46 5.89e-04 0.0 24 31.58 76 HNSC HNSC, BLCA, LUAD, UCEC, COAD, OV, BRCA, LUSC, SKCM
MAGEL2 Q9UJ55 MAGEL2 MAGE-like protein 2 chr15 Not Cancer Driver No 701-761 61 5.91e-04 100.0 25 13.97 179 - CESC, LIHC, SKCM, UCEC, KIRC, LUSC, LUAD, READ, COAD, HNSC, STAD
ZNF479_ENST00000319636 Q96JC4 ZNF479 Zinc finger protein 479 chr7 Census Yes 436-444 9 5.92e-04 0.0 20 6.37 314 LUAD, PRAD BLCA, LUAD, PRAD, UCEC, SKCM, LUSC, KIRC, HNSC, GBM
BEND4 Q6ZU67 BEND4 BEN domain-containing protein 4 chr4 Not Cancer Driver No 198-268 71 6.00e-04 71.83 33 30.84 107 SKCM UCEC, BRCA, LUAD, BLCA, STAD, SKCM, LUSC, CESC, LIHC
ADAMTS2 O95450 ADAMTS2 A disintegrin and metalloproteinase with thrombospondin motifs 2 chr5 Not Cancer Driver No 932-994 63 6.06e-04 22.22 38 12.5 304 LUAD READ, SKCM, BRCA, GBM, STAD, HNSC, UCEC, COAD, LUAD, BLCA
CCHCR1_ENST00000376266 Q8TD31 CCHCR1 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 102-112 11 6.07e-04 0.0 13 11.21 116 COAD COAD, KICH, KIRC, LIHC
IRX1 P78414 IRX1 Iroquois-class homeodomain protein IRX-1 chr5 Not Cancer Driver No 172-239 68 6.09e-04 77.94 50 31.06 161 - READ, LUAD, HNSC, BLCA, UCEC, BRCA, COAD, CESC, GBM, KIRC, LGG, LIHC, STAD, LUSC, SKCM, OV, PRAD
OR11H1 Q8NG94 OR11H1 Olfactory receptor 11H1 chr22 Not Cancer Driver No 76-80 5 6.13e-04 0.0 14 11.57 121 SKCM STAD, SKCM
DSP P15924 DSP Desmoplakin chr6 Not Cancer Driver No 1997-2041 45 6.14e-04 100.0 24 4.93 487 SKCM BRCA, PRAD, BLCA, HNSC, KIRC, COAD, SKCM, LUAD, CESC
ASPDH A6ND91 ASPDH Aspartate dehydrogenase domain-containing protein chr19 Not Cancer Driver No 266-266 1 6.14e-04 0.0 18 48.65 37 READ, COAD READ, COAD, REO
EPHA5_ENST00000273854 P54756 EPHA5 Ephrin type-A receptor 5 chr4 Not Cancer Driver No 469-478 10 6.15e-04 0.0 19 5.56 342 GBM SKCM, BRCA, GBM, LUAD, STAD, KIRC, BLCA
METTL14 Q9HCE5 METTL14 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 294-306 13 6.16e-04 0.0 11 18.33 60 UCEC PAAD, UCEC, LUAD, LGG, CESC, BLCA
CNTN5_ENST00000528682 O94779 CNTN5 Contactin-5 chr11 Not Cancer Driver No 372-383 12 6.23e-04 0.0 21 5.44 386 SKCM COAD, LUAD, SKCM, CESC
CHD4 Q14839 CHD4 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1098-1112 15 6.26e-04 0.0 18 4.26 423 UCEC UCEC, COAD, STAD, LUSC
KRT75 O95678 KRT75 Keratin, type II cytoskeletal 75 chr12 Not Cancer Driver No 429-435 7 6.27e-04 0.0 13 10.0 130 BLCA SKCM, BLCA, LIHC
HIST1H3B P68431 H3C12 Histone H3.1 chr6 Not Cancer Driver No 132-135 4 6.30e-04 25.0 15 18.75 80 BLCA DLBC, LUSC, LGG, SARC, SKCM, HNSC, BRCA, BLCA
CCDC96 Q2M329 CCDC96 Coiled-coil domain-containing protein 96 chr4 Not Cancer Driver No 96-96 1 6.40e-04 100.0 24 27.59 87 READ, COAD READ, COAD
PEG3 Q9GZU2 PEG3 Paternally-expressed gene 3 protein chr19 Compendium Yes 594-611 18 6.50e-04 100.0 24 3.99 602 - PRAD, SKCM, CESC, STAD, COAD, SARC, PAAD, LUAD, BRCA, GBM, UCEC, OV
ZNF804A Q7Z570 ZNF804A Zinc finger protein 804A chr2 Not Cancer Driver No 814-822 9 6.53e-04 100.0 18 3.53 510 SKCM SKCM, COAD, STAD, LUAD, HNSC, LUSC, SARC
AQP12B_ENST00000621682 A6NM10 AQP12B Aquaporin-12B chr2 Not Cancer Driver No 113-123 11 6.68e-04 0.0 15 28.85 52 BRCA COAD, SKCM, STAD, SARC, BRCA, READ, LUSC
LOR P23490 LORICRIN Loricrin chr1 Not Cancer Driver No 278-310 33 6.69e-04 100.0 10 66.67 15 SKCM READ, COAD, GBM, LUAD, STAD, LIHC, LUSC, SKCM
ELF3_ENST00000367283 P78545 ELF3 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 344-360 17 6.74e-04 0.0 10 10.64 94 BLCA, OV STAD, KIRC, BLCA, UCEC, OV
DCLK1 O15075 DCLK1 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 13-94 82 6.82e-04 52.44 49 23.44 209 - SKCM, KIRC, BRCA, HNSC, GBM, CESC, BLCA, LUAD, READ, STAD, OV, UCEC, COAD, LIHC
MATN4_ENST00000372754 O95460 MATN4 Matrilin-4 chr20 Not Cancer Driver No 164-170 7 6.82e-04 0.0 24 14.91 161 READ COAD, STAD, GBM, READ
VIT_ENST00000389975 Q6UXI7 VIT Vitrin chr2 Not Cancer Driver No 329-332 4 6.84e-04 0.0 13 8.18 159 UCEC READ, BRCA, UCEC, SKCM
PSD4 Q8NDX1 PSD4 PH and SEC7 domain-containing protein 4 chr2 Not Cancer Driver No 594-605 12 6.91e-04 0.0 13 8.23 158 GBM HNSC, LGG, OV, LIHC, STAD, GBM, SKCM, LUSC, LUAD
KCNH2 Q12809 KCNH2 Potassium voltage-gated channel subfamily H member 2 chr7 Not Cancer Driver No 505-552 48 6.93e-04 26.53 30 15.87 189 - OV, READ, SKCM, GBM, UCEC, LUSC, LUAD, CESC, THCA, STAD
C5 P01031 C5 Complement C5 chr9 Not Cancer Driver No 1196-1214 19 6.94e-04 0.0 16 8.25 194 SKCM SKCM, STAD, LGG, UCEC, KIRC
GSE1 Q14687 GSE1 Genetic suppressor element 1 chr16 Not Cancer Driver No 349-352 4 6.94e-04 100.0 1 0.86 116 READ READ, LIHC, COAD
CLEC5A Q9NY25 CLEC5A C-type lectin domain family 5 member A chr7 Not Cancer Driver No 76-124 49 6.98e-04 0.0 26 56.52 46 SKCM SKCM, LGG, BRCA, KIRC, LUAD, LUSC
HBZ P02008 HBZ Hemoglobin subunit zeta chr16 Not Cancer Driver No 8-28 21 6.99e-04 0.0 8 88.89 9 STAD, SKCM UCEC, THCA, STAD, SKCM
TCERG1L Q5VWI1 TCERG1L Transcription elongation regulator 1-like protein chr10 Not Cancer Driver No 290-312 23 7.00e-04 100.0 20 16.81 119 OV OV, SKCM, STAD, COAD, CESC, BRCA, KIRC, LUAD, UCEC, LUSC
SPTA1_ENST00000368147 P02549 SPTA1 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1728-1736 9 7.00e-04 0.0 19 1.77 1075 STAD STAD, COAD, CESC, UCEC, LUAD, LUSC, SKCM, BLCA, OV
KRTAP5-1 Q6L8H4 KRTAP5-1 Keratin-associated protein 5-1 chr11 Not Cancer Driver No 104-114 11 7.04e-04 100.0 6 12.77 47 BRCA LGG, BRCA, BLCA, SKCM
GSDMC Q9BYG8 GSDMC Gasdermin-C chr8 Not Cancer Driver No 33-48 16 7.05e-04 0.0 22 17.6 125 SKCM PAAD, HNSC, BRCA, STAD, SKCM, LGG, LUAD
IQSEC2_ENST00000396435 Q5JU85 IQSEC2 IQ motif and SEC7 domain-containing protein 2 chrX Not Cancer Driver No 983-1048 66 7.12e-04 0.0 25 15.34 163 - UCEC, LUSC, HNSC, LUAD, BLCA, THCA, SKCM, KIRC, OV, BRCA, LIHC
SLF1 Q9BQI6 SLF1 SMC5-SMC6 complex localization factor protein 1 chr5 Not Cancer Driver No 998-999 2 7.12e-04 100.0 10 9.62 104 SKCM KIRC, SKCM, LGG, PRAD, LUAD
ZNF133_ENST00000622607 P52736 ZNF133 Zinc finger protein 133 chr20 Not Cancer Driver No 357-357 1 7.12e-04 0.0 10 10.0 100 OV OV
AC093525.2 H3BQ06 AC093525.2 Rab-GAP TBC domain-containing protein chr16 Not Cancer Driver No 345-372 28 7.21e-04 100.0 17 32.08 53 SKCM SKCM, BLCA, LUAD, COAD, UCEC, STAD, GBM, HNSC, OV, THCA
JCAD Q9P266 JCAD Junctional protein associated with coronary artery disease chr10 Not Cancer Driver No 11-93 83 7.29e-04 96.47 38 12.88 295 SKCM UCEC, OV, PAAD, STAD, KIRC, BRCA, READ, GBM, HNSC, COAD, LUSC, BLCA, SKCM, LUAD
ELOA3 A0A8I5KDJ8 ELOA3 Uncharacterized protein chr18 Not Cancer Driver No 301-314 14 7.31e-04 100.0 17 15.89 107 BLCA, SKCM LUSC, BLCA, SKCM, UCEC, STAD, LUAD, LGG
P2RY8 Q86VZ1 P2RY8 P2Y purinoceptor 8 chrX Census, Compendium Yes 327-335 9 7.31e-04 100.0 16 12.5 128 GBM LUSC, UCEC, GBM, SKCM, PRAD, BLCA, STAD
FOLH1 Q04609 FOLH1 Glutamate carboxypeptidase 2 chr11 Not Cancer Driver No 278-281 4 7.32e-04 0.0 16 7.96 201 - SKCM, LUSC, COAD, LUAD, BLCA, BRCA, UCEC, READ
WWP2 O00308 WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 464-468 5 7.38e-04 80.0 10 8.85 113 GBM LUAD, STAD, UCEC, GBM, KIRC
SPDYE5 A6NIY4 SPDYE5 Speedy protein E5 chr7 Not Cancer Driver No 318-322 5 7.42e-04 100.0 10 37.04 27 LUAD LGG, PRAD, SKCM, LUAD
MYPOP Q86VE0 MYPOP Myb-related transcription factor, partner of profilin chr19 Not Cancer Driver No 363-399 37 7.44e-04 100.0 15 50.0 30 SKCM SKCM, GBM, BRCA, BLCA, UCEC, LUAD
KRT2 P35908 KRT2 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 92-103 12 7.46e-04 100.0 3 2.42 124 COAD COAD, CESC, READ
SLC30A8 Q8IWU4 SLC30A8 Zinc transporter 8 chr8 Not Cancer Driver No 181-188 8 7.47e-04 0.0 15 13.04 115 UCEC UCEC, LGG, SKCM, HNSC, GBM, OV, LIHC, STAD
ASPHD1 Q5U4P2 ASPHD1 Aspartate beta-hydroxylase domain-containing protein 1 chr16 Not Cancer Driver No 165-180 16 7.49e-04 75.0 4 7.55 53 UCEC, COAD UCEC, LUSC, READ, COAD
MAP3K4 Q9Y6R4 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 chr6 Not Cancer Driver No 1359-1371 13 7.58e-04 0.0 13 4.94 263 - COAD, BLCA, UCEC, SKCM, LGG, BRCA
DICER1 Q9UPY3 DICER1 Endoribonuclease Dicer chr14 Census, Compendium Yes 1699-1713 15 7.60e-04 0.0 16 5.99 267 UCEC UCEC, GBM, PRAD, LUSC, SARC, COAD, READ, SKCM
PARD3B Q8TEW8 PARD3B Partitioning defective 3 homolog B chr2 Not Cancer Driver No 1002-1009 8 7.60e-04 100.0 13 5.35 243 BLCA BLCA, SKCM
TRAPPC5 Q8IUR0 TRAPPC5 Trafficking protein particle complex subunit 5 chr19 Not Cancer Driver No 50-55 6 7.67e-04 0.0 22 57.89 38 READ, COAD READ, SKCM, COAD, BRCA
PCDHB4 Q9Y5E5 PCDHB4 Protocadherin beta-4 chr5 Not Cancer Driver No 306-311 6 7.68e-04 0.0 16 6.25 256 GBM, SKCM GBM, COAD, READ, SKCM
CDKN2A_ENST00000304494 P42771 CDKN2A Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 101-119 19 7.71e-04 0.0 45 27.11 166 - LIHC, HNSC, SKCM, OV, LUSC, READ, BLCA, LUAD, PAAD
ADAMTS7 Q9UKP4 ADAMTS7 A disintegrin and metalloproteinase with thrombospondin motifs 7 chr15 Not Cancer Driver No 1071-1080 10 7.73e-04 100.0 14 5.53 253 KIRC SKCM, LUSC, UCEC, KIRC, LGG
KRTAP10-4 P60372 KRTAP10-4 Keratin-associated protein 10-4 chr21 Not Cancer Driver No 45-49 5 7.75e-04 100.0 3 3.41 88 COAD BRCA, UCEC, COAD, GBM
PRG4 Q92954 PRG4 Proteoglycan 4 chr1 Not Cancer Driver No 396-404 9 7.76e-04 100.0 13 4.68 278 LUAD LGG, LUAD, OV, UCEC, PRAD, BRCA, KIRC
CCDC170 Q8IYT3 CCDC170 Coiled-coil domain-containing protein 170 chr6 Not Cancer Driver No 457-470 14 7.76e-04 0.0 15 10.27 146 SKCM STAD, READ, THCA, SKCM, BLCA, LUSC, LUAD
SPATA31D3 P0C874 SPATA31D3 Spermatogenesis-associated protein 31D3 chr9 Not Cancer Driver No 791-807 17 7.80e-04 100.0 10 24.39 41 - STAD, BRCA, UCEC, LUSC, SKCM, LUAD
PDYN P01213 PDYN Proenkephalin-B chr20 Not Cancer Driver No 174-180 7 7.86e-04 100.0 22 17.74 124 - HNSC, PAAD, SKCM, LUSC, COAD, BLCA, OV, KIRC, UCEC, BRCA, PRAD
DDR2 Q16832 DDR2 Discoidin domain-containing receptor 2 chr1 Census Yes 62-142 81 7.87e-04 0.0 37 19.27 192 GBM STAD, UCEC, HNSC, THCA, OV, SKCM, LUAD, KIRC, BRCA, GBM, COAD
ZNF626 Q68DY1 ZNF626 Zinc finger protein 626 chr19 Compendium Yes 368-368 1 7.92e-04 0.0 10 6.37 157 BLCA BLCA
TREX2_ENST00000370231 Q9BQ50 TREX2 Three prime repair exonuclease 2 chrX Not Cancer Driver No 28-63 36 7.94e-04 0.0 19 57.58 33 - LUSC, LUAD, BRCA, PAAD, SKCM, CESC, STAD, UCEC, HNSC, LIHC
SEMG2 Q02383 SEMG2 Semenogelin-2 chr20 Not Cancer Driver No 291-292 2 7.99e-04 100.0 10 6.71 149 GBM LGG, GBM, BRCA, UCEC, SKCM, READ
GPRIN2_ENST00000374314 O60269 GPRIN2 G protein-regulated inducer of neurite outgrowth 2 chr10 Not Cancer Driver No 39-39 1 8.06e-04 100.0 10 6.8 147 BRCA, READ, COAD BRCA, READ, COAD
ITGAV P06756 ITGAV Integrin alpha-V chr2 Census Yes 775-778 4 8.09e-04 0.0 10 6.54 153 GBM GBM, LUSC
RBAK_ENST00000353796 Q9NYW8 RBAK RB-associated KRAB zinc finger protein chr7 Not Cancer Driver No 507-555 49 8.11e-04 67.35 21 19.63 107 OV OV, COAD, LUAD, LGG, UCEC, KIRC, STAD, BLCA, SKCM, LUSC
PCDHGB2 Q9Y5G2 PCDHGB2 Protocadherin gamma-B2 chr5 Not Cancer Driver No 488-573 86 8.19e-04 0.0 46 20.35 226 - LUSC, SKCM, STAD, BLCA, BRCA, CESC, GBM, HNSC, COAD, LUAD, PRAD, UCEC
UGT2B28 Q9BY64 UGT2B28 UDP-glucuronosyltransferase 2B28 chr4 Not Cancer Driver No 386-401 16 8.19e-04 0.0 21 12.43 169 LUAD LUAD, LUSC, STAD, SKCM, GBM
VWA3A A6NCI4 VWA3A von Willebrand factor A domain-containing protein 3A chr16 Not Cancer Driver No 1010-1013 4 8.21e-04 0.0 10 5.29 189 BLCA BRCA, BLCA, LGG
ANKRD20A2 Q5SQ80 ANKRD20A2P Putative ankyrin repeat domain-containing protein 20A2 chr9 Not Cancer Driver No 44-60 17 8.24e-04 5.88 8 53.33 15 - COAD, CESC, BRCA, THCA, LUSC, SKCM, KIRC, STAD
TBXT O15178 TBXT T-box transcription factor T chr6 Not Cancer Driver No 367-429 63 8.25e-04 100.0 39 34.51 113 - GBM, STAD, COAD, HNSC, READ, LUAD, SARC, UCEC, LIHC, OV, CESC, BRCA, LUSC, SKCM, BLCA
ARHGAP33_ENST00000378944 O14559-10 ARHGAP33 Isoform 2 of Rho GTPase-activating protein 33 chr19 Not Cancer Driver No 1019-1041 23 8.26e-04 100.0 17 11.11 153 SKCM LUSC, SKCM, STAD, THCA, BLCA, LUAD, COAD, KIRC
PPP1R3A Q16821 PPP1R3A Protein phosphatase 1 regulatory subunit 3A chr7 Not Cancer Driver No 525-529 5 8.26e-04 100.0 13 3.0 433 SKCM OV, UCEC, LUSC, SKCM, KIRC
ZNF814 B7Z6K7 ZNF814 Zinc finger protein 814 chr19 Compendium Yes 337-337 1 8.35e-04 0.0 10 5.21 192 KIRC PRAD, COAD, KIRC, READ, GBM
TMC5 Q6UXY8 TMC5 Transmembrane channel-like protein 5 chr16 Not Cancer Driver No 276-276 1 8.40e-04 100.0 11 5.53 199 SKCM SKCM
STAT3 P40763 STAT3 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 609-661 53 8.41e-04 0.0 24 21.82 110 - GBM, CESC, BRCA, STAD, HNSC, DLBC, UCEC, PRAD, LUSC, SKCM, LIHC
LILRB1_ENST00000396331 Q8NHL6 LILRB1 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 Not Cancer Driver No 174-191 18 8.42e-04 16.67 22 10.84 203 - BLCA, READ, LUAD, HNSC, PRAD, SKCM, STAD, UCEC, LUSC, LGG, KIRC
BCL9 O00512 BCL9 B-cell CLL/lymphoma 9 protein chr1 Census, Compendium Yes 797-798 2 8.55e-04 100.0 10 4.55 220 BLCA LGG, BLCA
MAGI1 Q96QZ7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 788-789 2 8.65e-04 100.0 10 3.85 260 - SKCM, COAD, LGG, READ, GBM, BLCA, HNSC, DLBC, STAD
DCAF8 Q5TAQ9 DCAF8 DDB1- and CUL4-associated factor 8 chr1 Not Cancer Driver No 85-135 51 8.72e-04 100.0 16 18.82 85 UCEC LUSC, LUAD, STAD, BLCA, SARC, SKCM, UCEC, HNSC, LGG, BRCA
HOXB1 P14653 HOXB1 Homeobox protein Hox-B1 chr17 Not Cancer Driver No 22-29 8 8.73e-04 100.0 5 6.94 72 COAD COAD, READ, SKCM, KIRC, LIHC, UCEC, REO
MSR1 P21757 MSR1 Macrophage scavenger receptor types I and II chr8 Not Cancer Driver No 98-108 11 8.75e-04 100.0 22 13.02 169 SKCM OV, HNSC, LUSC, BLCA, SKCM
DOCK4 Q8N1I0 DOCK4 Dedicator of cytokinesis protein 4 chr7 Not Cancer Driver No 1889-1958 70 8.76e-04 100.0 29 8.71 333 - HNSC, READ, SKCM, STAD, BRCA, PAAD, CESC, LUSC, GBM, BLCA, LUAD, UCEC, COAD, KIRC
KLF1 Q13351 KLF1 Krueppel-like factor 1 chr19 Not Cancer Driver No 102-102 1 8.81e-04 100.0 18 42.86 42 READ, COAD READ, COAD
MICAL2_ENST00000646065 O94851 MICAL2 [F-actin]-monooxygenase MICAL2 chr11 Not Cancer Driver No 1328-1330 3 8.83e-04 100.0 14 4.64 302 BLCA BLCA, UCEC
MYO10 Q9HD67 MYO10 Unconventional myosin-X chr5 Not Cancer Driver No 1223-1223 1 8.84e-04 100.0 10 3.34 299 UCEC UCEC, STAD, COAD, READ
CACNA1H O95180 CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H chr16 Not Cancer Driver No 184-263 80 8.86e-04 7.5 33 9.88 334 - BLCA, OV, KIRC, PAAD, CESC, SKCM, READ, HNSC, LUSC, STAD, COAD, BRCA, UCEC
FBXW7_ENST00000603841 Q969H0 FBXW7 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 423-423 1 8.98e-04 0.0 10 3.11 322 UCEC HNSC, UCEC
ARID3A Q99856 ARID3A AT-rich interactive domain-containing protein 3A chr19 Not Cancer Driver No 547-559 13 8.99e-04 100.0 14 25.45 55 STAD READ, STAD, HNSC, SKCM, UCEC, COAD
GREB1_ENST00000234142 Q4ZG55 GREB1 Protein GREB1 chr2 Not Cancer Driver No 1925-1933 9 9.08e-04 0.0 10 3.15 317 GBM STAD, GBM, LUAD, SARC
MALL Q13021 MALL MAL-like protein chr2 Not Cancer Driver No 38-67 30 9.19e-04 0.0 15 75.0 20 SKCM KIRC, PAAD, SKCM, LUSC, KICH, STAD
SOX17 Q9H6I2 SOX17 Transcription factor SOX-17 chr8 Compendium Yes 67-142 76 9.29e-04 0.0 35 42.68 82 - COAD, PRAD, STAD, HNSC, LUSC, CESC, LGG, LUAD, SKCM, READ, UCEC, GBM
PENK_ENST00000451791 P01210 PENK Proenkephalin-A chr8 Not Cancer Driver No 200-265 66 9.33e-04 97.06 49 44.55 110 SKCM GBM, LUAD, SARC, THCA, KIRC, SKCM, OAD, UCEC, LGG, BLCA, HNSC, OV, LUSC
OVGP1 Q12889 OVGP1 Oviduct-specific glycoprotein chr1 Not Cancer Driver No 533-540 8 9.39e-04 100.0 2 1.75 114 READ, LAML READ, LAML
KRTAP17-1 Q9BYP8 KRTAP17-1 Keratin-associated protein 17-1 chr17 Not Cancer Driver No 42-54 13 9.40e-04 100.0 7 29.17 24 COAD BRCA, COAD, LGG, SKCM, READ
CPED1 A4D0V7 CPED1 Cadherin-like and PC-esterase domain-containing protein 1 chr7 Not Cancer Driver No 939-951 13 9.44e-04 0.0 16 6.53 245 LUAD, SKCM LUAD, UCEC, SKCM, LUSC
SF3B1 O75533 SF3B1 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 894-907 14 9.44e-04 0.0 15 6.12 245 BLCA LUSC, BLCA, LUAD, SKCM, HNSC, UCEC
FGFR2_ENST00000358487 P21802 FGFR2 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 544-552 9 9.52e-04 0.0 19 7.98 238 UCEC, BRCA SKCM, UCEC, BRCA, LUAD, BLCA
KLHDC7B Q96G42 KLHDC7B Kelch domain-containing protein 7B chr22 Not Cancer Driver No 497-504 8 9.53e-04 0.0 20 25.0 80 READ LGG, BLCA, COAD, SARC, READ, STAD
RGS7_ENST00000366563 P49802 RGS7 Regulator of G-protein signaling 7 chr1 Census, Compendium Yes 40-48 9 9.56e-04 0.0 17 8.67 196 SKCM LIHC, HNSC, SKCM, LUSC, LUAD
ISX_ENST00000404699 Q2M1V0 ISX Intestine-specific homeobox chr22 Census Yes 78-87 10 9.59e-04 63.64 16 24.62 65 SKCM SKCM, LUAD, LUSC, HNSC, UCEC, STAD
PCDHGA8 Q9Y5G5 PCDHGA8 Protocadherin gamma-A8 chr5 Not Cancer Driver No 637-698 62 9.61e-04 40.32 35 14.52 241 LUSC LUAD, GBM, READ, UCEC, PAAD, LUSC, CESC, SKCM, STAD, BLCA, COAD
MUC5AC P98088 MUC5AC Mucin-5AC chr11 Not Cancer Driver No 29-94 66 9.63e-04 100.0 17 6.97 244 - BLCA, SKCM, LUSC, UCEC, COAD, CESC, SARC, THCA, LUAD, GBM, KIRC
POTEF A5A3E0 POTEF POTE ankyrin domain family member F chr2 Not Cancer Driver No 716-738 23 9.66e-04 0.0 20 7.38 271 LUAD, UCEC LUSC, SKCM, CESC, GBM, LUAD, COAD, UCEC, HNSC, BRCA
SLURP2 P0DP57 SLURP2 Secreted Ly-6/uPAR domain-containing protein 2 chr8 Not Cancer Driver No 74-91 18 9.69e-04 22.22 10 71.43 14 GBM SKCM, LUSC, BRCA, STAD, GBM
COL21A1 Q96P44 COL21A1 Collagen alpha-1(XXI) chain chr6 Not Cancer Driver No 692-701 10 9.71e-04 100.0 18 6.04 298 SKCM SKCM
FAM47B Q8NA70 FAM47B Protein FAM47B chrX Not Cancer Driver No 243-249 7 9.75e-04 100.0 18 6.41 281 LUAD LGG, BRCA, BLCA, READ, LUAD, HNSC, UCEC, LUSC
SP8_ENST00000361443 Q8IXZ3 SP8 Transcription factor Sp8 chr7 Not Cancer Driver No 147-147 1 9.77e-04 100.0 0 0.0 37 COAD, READ COAD, READ
ZEB2_ENST00000558170 O60315 ZEB2 Zinc finger E-box-binding homeobox 2 chr2 Not Cancer Driver No 1090-1099 10 9.78e-04 90.0 15 5.02 299 BLCA SKCM, LUSC, HNSC, CESC, BRCA, COAD, UCEC, BLCA
LRFN5 Q96NI6 LRFN5 Leucine-rich repeat and fibronectin type-III domain-containing protein 5 chr14 Not Cancer Driver No 278-342 65 9.83e-04 0.0 54 17.25 313 - LGG, SKCM, READ, LUAD, COAD, HNSC, LIHC, SARC, STAD, UCEC, LUSC, GBM, BRCA, BLCA
GAL3ST2 Q9H3Q3 GAL3ST2 Galactose-3-O-sulfotransferase 2 chr2 Not Cancer Driver No 49-105 57 9.83e-04 0.0 18 47.37 38 STAD SKCM, LUSC, UCEC, KICH, KIRC, SARC, LUAD, GBM, READ, STAD
CAPS2 Q9BXY5 CAPS2 Calcyphosin-2 chr12 Not Cancer Driver No 303-315 13 9.87e-04 0.0 13 14.29 91 STAD LUSC, COAD, LIHC, HNSC, STAD, LUAD, BLCA, GBM, UCEC
FOXD4L5 Q5VV16 FOXD4L5 Forkhead box protein D4-like 5 chr9 Not Cancer Driver No 72-126 55 9.87e-04 63.64 29 43.28 67 - UCEC, GBM, READ, BLCA, COAD, LIHC, LUSC, STAD, HNSC, SKCM, LUAD
KIR2DL1 P43626 KIR2DL1 Killer cell immunoglobulin-like receptor 2DL1 chr19 Not Cancer Driver No 62-117 56 9.88e-04 0.0 40 35.71 112 - GBM, PRAD, LUSC, SKCM, LUAD, HNSC, UCEC, BRCA, STAD, LIHC, KICH, READ, SARC, OV, LGG, CESC
THBS2 P35442 THBS2 Thrombospondin-2 chr6 Not Cancer Driver No 37-99 63 9.96e-04 0.0 34 13.65 249 - UCEC, READ, CESC, LUAD, BLCA, HNSC, LGG, KIRC, OV, STAD, THCA, SKCM, COAD, LUSC
NBPF1 Q3BBV0-2 NBPF1 Isoform 2 of Neuroblastoma breakpoint family member 1 chr1 Not Cancer Driver No 905-924 20 1.00e-03 100.0 23 9.58 240 SKCM CESC, BLCA, SKCM, STAD, UCEC, HNSC, BRCA, KIRC, LUSC, LGG
POTEC B2RU33 POTEC POTE ankyrin domain family member C chr18 Not Cancer Driver No 505-514 10 1.01e-03 90.0 22 7.83 281 - BLCA, LUAD, LGG, SKCM, CESC, GBM, PRAD, KIRC
PLCZ1 Q86YW0 PLCZ1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 chr12 Not Cancer Driver No 293-326 34 1.01e-03 35.29 23 15.23 151 SKCM BLCA, KIRC, LUSC, SKCM, LGG, HNSC, LUAD, COAD, BRCA
OPRPN Q99935 OPRPN Opiorphin prepropeptide chr4 Not Cancer Driver No 122-136 15 1.01e-03 100.0 19 21.11 90 SKCM HNSC, PRAD, SKCM, LUSC, GBM, READ
PANX3 Q96QZ0 PANX3 Pannexin-3 chr11 Not Cancer Driver No 16-36 21 1.01e-03 33.33 18 19.57 92 LUSC STAD, SKCM, BRCA, LUAD, CESC, UCEC, LUSC
IK Q13123 IK Protein Red chr5 Not Cancer Driver No 326-399 74 1.02e-03 44.59 22 36.07 61 COAD CESC, BRCA, BLCA, SKCM, STAD, KIRC, COAD, UCEC, READ, SARC
RIMS1 Q86UR5 RIMS1 Regulating synaptic membrane exocytosis protein 1 chr6 Not Cancer Driver No 65-77 13 1.02e-03 100.0 16 3.97 403 - LUAD, COAD, BRCA, LIHC, KIRC, STAD, READ, OV, LUSC, BLCA, SKCM
KRTAP24-1 Q3LI83 KRTAP24-1 Keratin-associated protein 24-1 chr21 Not Cancer Driver No 59-82 24 1.04e-03 100.0 15 20.27 74 BRCA, LUAD STAD, COAD, BLCA, GBM, LUSC, BRCA, LUAD, SKCM
HOMEZ Q8IX15 HOMEZ Homeobox and leucine zipper protein Homez chr14 Not Cancer Driver No 537-545 9 1.05e-03 100.0 11 12.94 85 READ, COAD CESC, READ, COAD, UCEC
PCDHA3 Q9Y5H8 PCDHA3 Protocadherin alpha-3 chr5 Not Cancer Driver No 616-630 15 1.06e-03 26.67 20 5.65 354 SKCM UCEC, COAD, SKCM, HNSC, LUSC, LUAD, STAD
ZFP36L2 P47974 ZFP36L2 mRNA decay activator protein ZFP36L2 chr2 Not Cancer Driver No 154-163 10 1.06e-03 0.0 12 16.44 73 BLCA KIRC, LUSC, LIHC, BRCA, BLCA, SKCM, UCEC
FSIP2 Q5CZC0 FSIP2 Fibrous sheath-interacting protein 2 chr2 Not Cancer Driver No 6118-6198 81 1.08e-03 100.0 25 6.27 399 SKCM LUAD, LUSC, BRCA, SKCM, GBM, OV, BLCA, UCEC, CESC
PXDNL A1KZ92 PXDNL Probable oxidoreductase PXDNL chr8 Not Cancer Driver No 923-930 8 1.08e-03 0.0 16 2.84 564 SKCM SARC, STAD, COAD, SKCM, UCEC
GATD3A P0DPI2 GATD3 Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial chr21 Not Cancer Driver No 183-196 14 1.08e-03 0.0 12 37.5 32 LUAD UCEC, KIRC, HNSC, LUAD, STAD, SARC
KRT13 P13646 KRT13 Keratin, type I cytoskeletal 13 chr17 Not Cancer Driver No 201-206 6 1.08e-03 0.0 12 13.33 90 GBM LGG, SKCM, UCEC, STAD, GBM, LIHC
ZNF709 Q8N972 ZNF709 Zinc finger protein 709 chr19 Not Cancer Driver No 408-420 13 1.08e-03 0.0 14 10.61 132 LGG, PRAD LGG, SKCM, PRAD, KIRC, LUAD, GBM
CELSR2 Q9HCU4 CELSR2 Cadherin EGF LAG seven-pass G-type receptor 2 chr1 Not Cancer Driver No 16-16 1 1.08e-03 100.0 0 0.0 350 READ, COAD READ, COAD
NBPF12 Q5TAG4 NBPF12 Neuroblastoma breakpoint family member 12 chr1 Not Cancer Driver No 119-137 19 1.09e-03 42.11 9 21.43 42 KIRC BLCA, UCEC, KIRC, BRCA, LUSC
SLAIN1_ENST00000466548 Q8ND83 SLAIN1 SLAIN motif-containing protein 1 chr13 Not Cancer Driver No 508-555 48 1.09e-03 100.0 27 43.55 62 SKCM COAD, LUSC, BLCA, STAD, LUAD, BRCA, OV, UCEC, SKCM
SMARCA4 P51532 SMARCA4 Transcription activator BRG1 chr19 Census, Compendium Yes 905-921 17 1.09e-03 5.88 17 4.8 354 - KIRC, GBM, HNSC, BLCA, UCEC, LUAD, STAD, LGG, LIHC
SCAI_ENST00000336505 Q8N9R8 SCAI Protein SCAI chr9 Not Cancer Driver No 125-132 8 1.12e-03 0.0 12 12.5 96 PRAD, KIRC LUAD, PRAD, LUSC, KIRC, BLCA
SLC22A24 Q8N4F4 SLC22A24 Steroid transmembrane transporter SLC22A24 chr11 Not Cancer Driver No 37-78 42 1.12e-03 25.58 16 28.57 56 - HNSC, SKCM, LUSC, STAD, LUAD, KIRC
MUC4 Q99102 MUC4 Mucin-4 chr3 Census Yes 1125-1138 14 1.12e-03 100.0 16 1.55 1030 UCEC LUAD, SKCM, UCEC, KIRC
WT1_ENST00000379079 P19544-6 WT1 Isoform 6 of Wilms tumor protein chr11 Census, Compendium Yes 208-253 46 1.12e-03 100.0 26 37.68 69 LUAD COAD, LAML, LUAD, HNSC, THCA, BRCA, BLCA, STAD, LUSC, SKCM, LIHC, UCEC
CRB1 P82279 CRB1 Protein crumbs homolog 1 chr1 Not Cancer Driver No 622-633 12 1.13e-03 100.0 19 4.09 464 GBM GBM, READ, HNSC, STAD, LUSC, OV
ARHGEF5 Q12774 ARHGEF5 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 186-253 68 1.13e-03 100.0 24 14.12 170 SKCM HNSC, OV, DLBC, LUSC, LUAD, UCEC, CESC, GBM, SKCM
LNX2 Q8N448 LNX2 Ligand of Numb protein X 2 chr13 Not Cancer Driver No 176-241 66 1.14e-03 83.58 23 26.44 87 SKCM COAD, GBM, UCEC, BRCA, LUSC, BLCA, SKCM, STAD, OV, HNSC, READ, LUAD
CFAP47 Q6ZTR5 CFAP47 Cilia- and flagella-associated protein 47 chrX Not Cancer Driver No 509-583 75 1.14e-03 100.0 30 6.8 441 - GBM, LUAD, READ, BRCA, OV, LGG, STAD, UCEC, LUSC, BLCA, HNSC, SKCM, CESC
KRT6B P04259 KRT6B Keratin, type II cytoskeletal 6B chr12 Not Cancer Driver No 118-182 65 1.14e-03 72.31 30 24.19 124 - PAAD, CESC, OV, LUSC, BRCA, LIHC, BLCA, UCEC, KIRC, SKCM, LUAD, STAD
CSGALNACT2 Q8N6G5 CSGALNACT2 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 chr10 Not Cancer Driver No 357-362 6 1.14e-03 0.0 12 11.65 103 KIRC, UCEC LUSC, KIRC, UCEC
EGFR P00533 EGFR Epidermal growth factor receptor chr7 Census, Compendium Yes 105-114 10 1.14e-03 0.0 17 3.81 446 GBM OV, GBM, LGG, BRCA, SKCM
UQCRC2 P22695 UQCRC2 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 301-304 4 1.14e-03 50.0 9 16.67 54 GBM LUSC, GBM
CNTNAP2 Q9UHC6 CNTNAP2 Contactin-associated protein-like 2 chr7 Census Yes 380-392 13 1.15e-03 0.0 23 4.01 573 - SKCM, UCEC, PRAD, LIHC, LUAD, GBM, OV, COAD, BLCA
VSTM2L Q96N03 VSTM2L V-set and transmembrane domain-containing protein 2-like protein chr20 Not Cancer Driver No 50-85 36 1.16e-03 16.67 16 57.14 28 - HNSC, SKCM, LGG, OV, GBM, BLCA, COAD, LAML, LUSC, STAD, LUAD
ZNF728 P0DKX0 ZNF728 Zinc finger protein 728 chr19 Not Cancer Driver No 192-200 9 1.16e-03 100.0 14 12.17 115 SKCM LUSC, SKCM, UCEC
SPEM2 Q0P670 SPEM2 Uncharacterized protein SPEM2 chr17 Not Cancer Driver No 125-131 7 1.17e-03 100.0 13 12.75 102 COAD, STAD UCEC, COAD, STAD, SKCM
FOXE1 O00358 FOXE1 Forkhead box protein E1 chr9 Not Cancer Driver No 116-165 50 1.17e-03 39.22 19 50.0 38 STAD, BLCA CESC, LUSC, COAD, STAD, BLCA, SKCM, UCEC, READ
ROBO1 Q9Y6N7 ROBO1 Roundabout homolog 1 chr3 Not Cancer Driver No 3-67 65 1.18e-03 96.92 33 9.3 355 - BLCA, LUSC, LIHC, LUAD, COAD, READ, BRCA, SKCM, PRAD, SARC, STAD
FBXW9 Q5XUX1 FBXW9 F-box/WD repeat-containing protein 9 chr19 Not Cancer Driver No 368-382 15 1.18e-03 0.0 9 18.0 50 LUSC, OV STAD, LUSC, OV, KIRC, SARC
GOLGA6D P0CG33 GOLGA6D Golgin subfamily A member 6D chr15 Not Cancer Driver No 154-188 35 1.18e-03 0.0 14 34.15 41 GBM PRAD, BRCA, LUAD, BLCA, STAD, SKCM, GBM, LUSC
NHSL2 Q5HYW2 NHSL2 NHS-like protein 2 chrX Not Cancer Driver No 871-925 55 1.18e-03 100.0 21 16.8 125 SKCM BRCA, BLCA, UCEC, READ, CESC, STAD, SKCM, LUAD
PIK3R2_ENST00000617130 O00459 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 370-377 8 1.19e-03 0.0 13 13.4 97 UCEC BLCA, LUAD, KIRC, UCEC, LUSC
TBC1D2B Q9UPU7 TBC1D2B TBC1 domain family member 2B chr15 Not Cancer Driver No 912-926 15 1.19e-03 0.0 17 14.41 118 PRAD LAML, LUAD, OV, SKCM, READ, BRCA, PRAD, CESC
MAP2K1 Q02750 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 53-57 5 1.19e-03 0.0 12 12.77 94 LUAD, SKCM LUAD, COAD, READ, HNSC, SKCM
GJB3 O75712 GJB3 Gap junction beta-3 protein chr1 Not Cancer Driver No 158-160 3 1.20e-03 0.0 11 21.57 51 GBM SKCM, UCEC, COAD, GBM, BRCA, OV
CBL P22681 CBL E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 412-420 9 1.20e-03 0.0 13 11.3 115 SKCM GBM, LUAD, OV, SKCM
NAGPA Q9UK23 NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase chr16 Not Cancer Driver No 465-505 41 1.22e-03 69.77 19 38.78 49 - BLCA, UCEC, GBM, SKCM, LUAD, BRCA, OV, KIRC, COAD
TUSC1 Q2TAM9 TUSC1 Tumor suppressor candidate gene 1 protein chr9 Not Cancer Driver No 123-123 1 1.22e-03 100.0 18 58.06 31 READ, COAD READ, COAD
FLVCR1 Q9Y5Y0 FLVCR1 Feline leukemia virus subgroup C receptor-related protein 1 chr1 Not Cancer Driver No 52-54 3 1.24e-03 100.0 19 28.36 67 READ READ, COAD, BRCA
SIRPA_ENST00000400068 P78324 SIRPA Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 230-241 12 1.25e-03 0.0 17 16.83 101 - LUSC, PRAD, SKCM, LUAD, KIRC, BLCA, LGG, STAD
MST1 P26927 MST1 Hepatocyte growth factor-like protein chr3 Not Cancer Driver No 340-349 10 1.25e-03 0.0 12 10.62 113 PRAD, UCEC LGG, PRAD, UCEC, BLCA
RYR2 Q92736 RYR2 Ryanodine receptor 2 chr1 Not Cancer Driver No 4134-4146 13 1.25e-03 100.0 23 1.35 1709 - BLCA, LUSC, BRCA, KIRC, LIHC, LUAD, COAD, SKCM
DCAF8L2_ENST00000545306 P0C7V8 DCAF8L2 DDB1- and CUL4-associated factor 8-like protein 2 chrX Not Cancer Driver No 144-153 10 1.25e-03 100.0 3 1.86 161 COAD, READ UCEC, COAD, LIHC, READ
KDM6B_ENST00000448097 O15054 KDM6B Lysine-specific demethylase 6B chr17 Not Cancer Driver No 262-264 3 1.25e-03 100.0 0 0.0 190 UCEC, COAD UCEC, COAD
KTI12 Q96EK9 KTI12 Protein KTI12 homolog chr1 Not Cancer Driver No 111-121 11 1.25e-03 92.31 2 5.41 37 READ LUAD, BLCA, READ
TPRX1 Q8N7U7 TPRX1 Tetra-peptide repeat homeobox protein 1 chr19 Not Cancer Driver No 222-232 11 1.25e-03 100.0 5 6.58 76 READ, COAD KIRC, READ, COAD, BRCA, PRAD
MARK2 Q7KZI7 MARK2 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 707-715 9 1.25e-03 0.0 12 9.68 124 GBM GBM, CESC, LUAD, BRCA, SKCM
GNG13 Q9P2W3 GNG13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 chr16 Not Cancer Driver No 15-24 10 1.26e-03 0.0 12 70.59 17 STAD, LUAD STAD, LUAD
ROBO2_ENST00000461745 Q9HCK4 ROBO2 Roundabout homolog 2 chr3 Census Yes 17-60 44 1.26e-03 20.0 31 7.6 408 - READ, COAD, CESC, PRAD, BLCA, STAD, LUAD, KIRC, HNSC, LUSC, SKCM
PDZRN3 Q9UPQ7 PDZRN3 E3 ubiquitin-protein ligase PDZRN3 chr3 Not Cancer Driver No 917-977 61 1.27e-03 90.16 32 13.62 235 - OV, PRAD, HNSC, LIHC, LUSC, READ, GBM, KIRC, SKCM, BLCA, PAAD, BRCA, UCEC, STAD, LUAD
NPFFR1 Q9GZQ6 NPFFR1 Neuropeptide FF receptor 1 chr10 Not Cancer Driver No 23-84 62 1.28e-03 7.94 14 51.85 27 UCEC SKCM, PAAD, UCEC, READ, STAD, BLCA, COAD, LAML, LGG
OR2W1 Q9Y3N9 OR2W1 Olfactory receptor 2W1 chr6 Not Cancer Driver No 119-127 9 1.28e-03 0.0 15 16.3 92 SKCM OV, SKCM, COAD, UCEC, LUAD
PRDM7_ENST00000449207 Q9NQW5 PRDM7 Histone-lysine N-methyltransferase PRDM7 chr16 Not Cancer Driver No 386-390 5 1.29e-03 100.0 9 14.29 63 - LGG, LUAD, LIHC, CESC, SKCM, PRAD
ASH1L_ENST00000368346 Q9NR48 ASH1L Histone-lysine N-methyltransferase ASH1L chr1 Not Cancer Driver No 2499-2569 71 1.30e-03 100.0 28 6.75 415 - OV, LUSC, BLCA, LUAD, KIRC, STAD, READ, BRCA, SARC, COAD, UCEC
KIF2C Q99661 KIF2C Kinesin-like protein KIF2C chr1 Not Cancer Driver No 495-512 18 1.31e-03 84.21 21 17.95 117 SKCM GBM, SKCM, LUAD, BLCA, STAD, UCEC
ESR1_ENST00000206249 P03372 ESR1 Estrogen receptor chr6 Census, Compendium Yes 370-434 65 1.31e-03 16.92 20 15.87 126 - STAD, UCEC, BRCA, GBM, HNSC, BLCA, OV, COAD, LIHC, SKCM, LUAD, LUSC
CYFIP1_ENST00000610365 Q7L576 CYFIP1 Cytoplasmic FMR1-interacting protein 1 chr15 Not Cancer Driver No 1075-1123 49 1.33e-03 10.2 14 30.43 46 UCEC, SKCM, STAD UCEC, SKCM, BRCA, LUSC, STAD
DEFB114 Q30KQ6 DEFB114 Beta-defensin 114 chr6 Not Cancer Driver No 20-35 16 1.33e-03 41.18 20 62.5 32 SKCM STAD, COAD, SKCM, LIHC, BLCA, BRCA, DLBC, LUSC, GBM, OV
JAK2 O60674 JAK2 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 106-146 41 1.33e-03 0.0 18 13.24 136 LUAD, BRCA THCA, HNSC, LUSC, LUAD, BRCA, LIHC, BLCA, SKCM
GOLGA6L10 A6NI86 GOLGA6L10 Golgin subfamily A member 6-like protein 10 chr15 Not Cancer Driver No 151-151 1 1.34e-03 100.0 8 44.44 18 GBM, KIRC SKCM, GBM, LUAD, KIRC, LGG
OTOA_ENST00000286149 Q7RTW8 OTOA Otoancorin chr16 Not Cancer Driver No 197-208 12 1.35e-03 0.0 17 10.12 168 LUAD LIHC, STAD, BRCA, KIRC, GBM, LUAD, COAD, SKCM, LUSC
SERPINA5_ENST00000554276 P05154 SERPINA5 Plasma serine protease inhibitor chr14 Not Cancer Driver No 21-30 10 1.35e-03 100.0 16 15.24 105 SKCM LUSC, STAD, BLCA, BRCA, LUAD, SKCM, HNSC
SOGA3 Q5TF21 SOGA3 Protein SOGA3 chr6 Not Cancer Driver No 749-757 9 1.35e-03 100.0 12 6.67 180 HNSC UCEC, LUAD, COAD, STAD, HNSC, PRAD, CESC, SKCM
PIK3CG P48736 PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 Not Cancer Driver No 139-206 68 1.38e-03 2.94 42 13.0 323 LUSC UCEC, KIRC, PAAD, PRAD, SKCM, LUAD, READ, HNSC, LGG, STAD, COAD, LUSC, GBM
FAM89B Q8N5H3 FAM89B Leucine repeat adapter protein 25 chr11 Not Cancer Driver No 135-177 43 1.38e-03 100.0 12 85.71 14 SKCM LAML, SKCM, READ, LUAD, LUSC, BLCA, COAD, STAD
GAGE2A Q6NT46 GAGE2A G antigen 2A chrX Not Cancer Driver No 51-59 9 1.38e-03 100.0 10 62.5 16 UCEC UCEC, SKCM, LUAD, LGG
NFE4 Q86UQ8 NFE4 Transcription factor NF-E4 chr7 Not Cancer Driver No 13-62 50 1.38e-03 76.47 12 80.0 15 SKCM BLCA, HNSC, UCEC, SKCM, LUAD, LUSC, LGG
RNF222_ENST00000344001 A6NCQ9 RNF222 RING finger protein 222 chr17 Not Cancer Driver No 114-133 20 1.38e-03 100.0 20 80.0 25 READ, COAD READ, COAD
TMEM218 A2RU14 TMEM218 Transmembrane protein 218 chr11 Not Cancer Driver No 34-65 32 1.38e-03 0.0 13 92.86 14 SKCM LUSC, SKCM, LUAD, STAD, COAD, HNSC, READ
VPREB3 Q9UKI3 VPREB3 Pre-B lymphocyte protein 3 chr22 Not Cancer Driver No 47-77 31 1.38e-03 0.0 11 73.33 15 SKCM GBM, THCA, READ, LUSC, STAD, SKCM, COAD
CNGA3 Q16281 CNGA3 Cyclic nucleotide-gated cation channel alpha-3 chr2 Not Cancer Driver No 277-283 7 1.40e-03 0.0 12 6.52 184 SKCM, LIHC LUSC, READ, SKCM, COAD, SARC, LIHC
TXNRD3NB Q6F5E7 TXNRD3NB Putative uncharacterized protein TXNRD3NB chr3 Not Cancer Driver No 64-75 12 1.40e-03 0.0 12 46.15 26 - LUAD, SKCM, PAAD, BRCA, BLCA, HNSC
GRIA1_ENST00000285900 P42261 GRIA1 Glutamate receptor 1 chr5 Not Cancer Driver No 832-905 74 1.40e-03 91.89 47 15.46 304 SKCM STAD, OV, LUAD, BLCA, BRCA, PRAD, READ, LUSC, CESC, LIHC, SKCM, KIRC, HNSC, COAD, LGG, UCEC
CCDC15 Q0P6D6 CCDC15 Coiled-coil domain-containing protein 15 chr11 Not Cancer Driver No 458-458 1 1.40e-03 100.0 9 9.38 96 LUAD, PRAD CESC, LGG, LUAD, PRAD
GIMAP8 Q8ND71 GIMAP8 GTPase IMAP family member 8 chr7 Not Cancer Driver No 649-654 6 1.41e-03 0.0 15 7.5 200 SKCM BRCA, SARC, SKCM
FAM98C Q17RN3 FAM98C Protein FAM98C chr19 Not Cancer Driver No 309-349 41 1.41e-03 92.68 15 31.25 48 LUAD UCEC, STAD, HNSC, SKCM, BRCA, LUAD, COAD, GBM, LAML
PRAMEF12 O95522 PRAMEF12 PRAME family member 12 chr1 Not Cancer Driver No 84-97 14 1.41e-03 0.0 18 14.52 124 SKCM HNSC, SKCM, SARC, GBM, KIRC, LUAD, READ, PRAD, COAD, STAD, BLCA
CADM3_ENST00000368125 Q8N126 CADM3 Cell adhesion molecule 3 chr1 Not Cancer Driver No 178-245 68 1.41e-03 0.0 42 35.0 120 SKCM DLBC, KIRC, OV, STAD, BRCA, LUSC, COAD, LIHC, SKCM, LUAD, UCEC
NRCAM_ENST00000425651 Q92823 NRCAM Neuronal cell adhesion molecule chr7 Not Cancer Driver No 7-18 12 1.42e-03 100.0 14 6.6 212 BLCA COAD, READ, LUAD, BLCA, LUSC, CESC, HNSC, BRCA
NRG2 O14511 NRG2 Pro-neuregulin-2, membrane-bound isoform chr5 Not Cancer Driver No 521-587 67 1.43e-03 100.0 24 29.27 82 SKCM SKCM, GBM, HNSC, BRCA, LUAD, LUSC, READ, THCA
SPSB4 Q96A44 SPSB4 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 206-261 56 1.44e-03 0.0 24 57.14 42 SKCM LUAD, PRAD, STAD, BRCA, LUSC, HNSC, PAAD, BLCA, READ, LGG, SKCM
MYT1L Q9UL68 MYT1L Myelin transcription factor 1-like protein chr2 Not Cancer Driver No 433-500 68 1.44e-03 83.82 40 10.84 369 SKCM DLBC, LUSC, SKCM, OV, LIHC, LUAD, BRCA, COAD, PRAD, BLCA, STAD, GBM
SPON1 Q9HCB6 SPON1 Spondin-1 chr11 Not Cancer Driver No 217-233 17 1.44e-03 0.0 14 11.67 120 SKCM STAD, SKCM, BRCA, UCEC, LUSC, LUAD
ZNF646 O15015 ZNF646 Zinc finger protein 646 chr16 Not Cancer Driver No 504-512 9 1.45e-03 22.22 14 6.06 231 GBM BLCA, GBM, UCEC, STAD, SKCM, LUSC
CD209 Q9NNX6 CD209 CD209 antigen chr19 Census Yes 122-129 8 1.46e-03 62.5 15 12.93 116 PRAD KIRC, UCEC, LUAD, STAD, PRAD, SKCM, LGG
KRTAP10-2 P60368 KRTAP10-2 Keratin-associated protein 10-2 chr21 Not Cancer Driver No 187-194 8 1.46e-03 100.0 8 14.04 57 BLCA, COAD UCEC, BLCA, COAD
KIF21A Q7Z4S6 KIF21A Kinesin-like protein KIF21A chr12 Not Cancer Driver No 824-835 12 1.46e-03 100.0 12 4.69 256 LUAD, BLCA PRAD, UCEC, STAD, LUAD, SARC, LUSC, SKCM, BLCA
SF3B1 O75533 SF3B1 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 736-742 7 1.47e-03 0.0 13 5.31 245 LUAD UCEC, PRAD, LIHC, BLCA, LUAD, SKCM, KIRC, PAAD
ANKRD27 Q96NW4 ANKRD27 Ankyrin repeat domain-containing protein 27 chr19 Not Cancer Driver No 760-775 16 1.48e-03 0.0 22 14.1 156 UCEC BRCA, STAD, UCEC, LUSC, LUAD, COAD, SKCM, READ
GRK1 Q15835 GRK1 Rhodopsin kinase GRK1 chr13 Not Cancer Driver No 264-323 60 1.48e-03 0.0 22 31.43 70 - UCEC, LUSC, COAD, PRAD, CESC, STAD, OV, BRCA, HNSC, SKCM, READ, BLCA
XKR7 Q5GH72 XKR7 XK-related protein 7 chr20 Not Cancer Driver No 478-531 54 1.49e-03 100.0 28 24.78 113 - LIHC, COAD, LUAD, SARC, CESC, GBM, LUSC, UCEC, SKCM, BRCA, BLCA, STAD
MMP3 P08254 MMP3 Stromelysin-1 chr11 Not Cancer Driver No 316-318 3 1.50e-03 0.0 9 9.0 100 GBM OV, LUAD, UCEC, GBM, STAD
STRC Q7RTU9 STRC Stereocilin chr15 Not Cancer Driver No 1519-1524 6 1.50e-03 0.0 9 10.0 90 SKCM LUAD, SKCM, LUSC
MUC5B Q9HC84 MUC5B Mucin-5B chr11 Not Cancer Driver No 3660-3712 53 1.51e-03 100.0 25 2.64 946 - READ, COAD, SKCM, HNSC, OV, LUSC, CESC, BLCA, LUAD, BRCA, UCEC
KNDC1 Q76NI1 KNDC1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 Not Cancer Driver No 801-806 6 1.51e-03 100.0 23 7.85 293 COAD, READ COAD, READ
TAS2R3 Q9NYW6 TAS2R3 Taste receptor type 2 member 3 chr7 Not Cancer Driver No 241-251 11 1.51e-03 0.0 10 20.41 49 LAML, KIRC BRCA, LAML, KIRC
OR11H12 B2RN74 OR11H12 Olfactory receptor 11H12 chr14 Not Cancer Driver No 79-84 6 1.51e-03 0.0 14 10.53 133 SKCM STAD, READ, SKCM, SARC, UCEC, BLCA, PAAD
DLST P36957 DLST Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 208-258 51 1.51e-03 28.85 19 35.85 53 - HNSC, COAD, OV, STAD, LIHC, CESC, LUSC, LUAD
CCDC144A A2RUR9 CCDC144A Coiled-coil domain-containing protein 144A chr17 Not Cancer Driver No 70-109 40 1.52e-03 85.0 19 10.38 183 - STAD, KIRC, PRAD, BRCA, CESC, BLCA, SKCM, LUAD, HNSC, LUSC, UCEC
IGF2BP1 Q9NZI8 IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 Not Cancer Driver No 158-174 17 1.52e-03 100.0 17 12.06 141 - UCEC, GBM, LUAD, STAD, LUSC, SKCM, SARC, READ, COAD, BRCA
NIPAL1 Q6NVV3 NIPAL1 Magnesium transporter NIPA3 chr4 Not Cancer Driver No 181-222 42 1.52e-03 9.52 12 23.53 51 BLCA, SKCM READ, BLCA, CESC, SKCM
AKAP3 O75969 AKAP3 A-kinase anchor protein 3 chr12 Not Cancer Driver No 248-269 22 1.52e-03 100.0 19 11.45 166 LUSC LUAD, OV, LUSC, BRCA, HNSC, CESC, STAD, BLCA, UCEC, SKCM
CRB2 Q5IJ48 CRB2 Protein crumbs homolog 2 chr9 Not Cancer Driver No 135-159 25 1.52e-03 0.0 27 16.27 166 COAD BLCA, READ, STAD, COAD, LUAD, SKCM
FAT4 Q6V0I7 FAT4 Protocadherin Fat 4 chr4 Census, Compendium Yes 4484-4537 54 1.54e-03 100.0 35 2.64 1326 SKCM READ, BLCA, UCEC, OV, LUAD, BRCA, COAD, SKCM, KIRC
FOXD3 Q9UJU5 FOXD3 Forkhead box protein D3 chr1 Not Cancer Driver No 227-269 43 1.54e-03 90.7 13 40.62 32 STAD KIRC, COAD, BRCA, SARC, CESC, LUAD, STAD, OV
MYLK Q15746 MYLK Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 952-961 10 1.54e-03 100.0 12 3.47 346 SKCM BLCA, COAD, BRCA, SKCM
OR51A4_ENST00000380373 Q8NGJ6 OR51A4 Olfactory receptor 51A4 chr11 Not Cancer Driver No 131-203 73 1.54e-03 0.0 45 39.47 114 SKCM OV, LUSC, LGG, DLBC, BRCA, HNSC, SKCM, LUAD, COAD, GBM, SARC, STAD, LIHC, BLCA
ZNF780A_ENST00000595687 O75290 ZNF780A Zinc finger protein 780A chr19 Compendium Yes 598-599 2 1.54e-03 0.0 9 7.03 128 PRAD KIRC, PRAD, LUAD, CESC
CFAP20 Q9Y6A4 CFAP20 Cilia- and flagella-associated protein 20 chr16 Not Cancer Driver No 99-100 2 1.55e-03 0.0 9 34.62 26 STAD, COAD, CESC BRCA, STAD, COAD, CESC
RARA P10276 RARA Retinoic acid receptor alpha chr17 Census, Compendium Yes 272-303 32 1.55e-03 0.0 19 27.14 70 - COAD, BRCA, BLCA, STAD, LUAD, SKCM, UCEC
GOLGA8F A0A0G2JP48 GOLGA8G Putative golgin subfamily A member 8F/8G chr15 Not Cancer Driver No 439-467 29 1.55e-03 100.0 10 66.67 15 SKCM LUAD, UCEC, CESC, READ, SKCM, HNSC
GABRG2_ENST00000639213 P18507 GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 Not Cancer Driver No 372-384 13 1.55e-03 100.0 18 9.52 189 - COAD, READ, LUSC, LIHC, SKCM, LUAD, KIRC, STAD, BRCA
TMEM175 Q9BSA9 TMEM175 Endosomal/lysosomal potassium channel TMEM175 chr4 Not Cancer Driver No 199-206 8 1.55e-03 0.0 7 8.97 78 BLCA SKCM, CESC, READ, STAD, BRCA, BLCA
SPERT Q8NA61 CBY2 Protein chibby homolog 2 chr13 Not Cancer Driver No 329-329 1 1.55e-03 100.0 20 17.7 113 COAD, READ COAD, READ
MTOR P42345 MTOR Serine/threonine-protein kinase mTOR chr1 Census, Compendium Yes 1971-1981 11 1.55e-03 0.0 12 3.15 381 UCEC, KIRC CESC, BRCA, UCEC, KIRC, GBM, PRAD
OR1S1 Q8NH92 OR1S1 Olfactory receptor 1S1 chr11 Not Cancer Driver No 46-54 9 1.56e-03 0.0 16 10.96 146 CESC, UCEC, SKCM CESC, UCEC, LUAD, KIRC, SKCM
TLK2 Q86UE8 TLK2 Serine/threonine-protein kinase tousled-like 2 chr17 Not Cancer Driver No 259-262 4 1.57e-03 100.0 9 7.44 121 KIRC, UCEC KIRC, UCEC, LUAD
HCRTR2 O43614 HCRTR2 Orexin receptor type 2 chr6 Not Cancer Driver No 248-253 6 1.57e-03 16.67 20 12.99 154 SKCM BLCA, SKCM, STAD, READ, KIRC, PRAD
VANGL1 Q8TAA9 VANGL1 Vang-like protein 1 chr1 Not Cancer Driver No 327-338 12 1.57e-03 91.67 7 9.59 73 GBM KIRC, READ, GBM, BRCA, LIHC, STAD
KCNJ12_ENST00000331718 Q14500 KCNJ12 ATP-sensitive inward rectifier potassium channel 12 chr17 Not Cancer Driver No 30-46 17 1.58e-03 73.68 33 12.99 254 - UCEC, SARC, HNSC, KIRC, PAAD, GBM, LGG, LAML, BRCA, OV, COAD, LUAD, SKCM, READ, STAD
CAND2 O75155 CAND2 Cullin-associated NEDD8-dissociated protein 2 chr3 Not Cancer Driver No 336-398 63 1.59e-03 17.46 19 13.87 137 LUAD STAD, UCEC, GBM, LUAD, BRCA, LIHC, LUSC, PRAD
GOLGA6B A6NDN3 GOLGA6B Golgin subfamily A member 6B chr15 Not Cancer Driver No 345-360 16 1.59e-03 0.0 15 28.85 52 LUAD LUSC, BLCA, UCEC, LUAD, OV
LCE2D Q5TA82 LCE2D Late cornified envelope protein 2D chr1 Not Cancer Driver No 78-89 12 1.60e-03 100.0 21 45.65 46 LUAD LUAD, BRCA, BLCA, STAD, PRAD, UCEC, HNSC, COAD
TRIM43 Q96BQ3 TRIM43 Tripartite motif-containing protein 43 chr2 Not Cancer Driver No 130-180 51 1.60e-03 0.0 18 37.5 48 - UCEC, BRCA, LGG, LUSC, KIRC, READ, THCA, PRAD, HNSC, LIHC
RP1L1 Q8IWN7 RP1L1 Retinitis pigmentosa 1-like 1 protein chr8 Not Cancer Driver No 1859-1868 10 1.60e-03 100.0 9 1.5 602 COAD READ, KIRC, BRCA, BLCA, COAD
ADGRA1 Q86SQ6 ADGRA1 Adhesion G protein-coupled receptor A1 chr10 Not Cancer Driver No 27-66 40 1.60e-03 0.0 21 27.63 76 SKCM KIRC, BLCA, THCA, UCEC, LIHC, LUSC, SKCM, STAD, OV
DACT1 Q9NYF0 DACT1 Dapper homolog 1 chr14 Not Cancer Driver No 697-714 18 1.61e-03 100.0 19 11.52 165 UCEC CESC, LUAD, BLCA, UCEC, PRAD, STAD, COAD, SKCM, PAAD
RGPD8 O14715 RGPD8 RANBP2-like and GRIP domain-containing protein 8 chr2 Not Cancer Driver No 1137-1145 9 1.61e-03 0.0 9 6.98 129 SKCM, BLCA SKCM, CESC, UCEC, PAAD, BLCA
OR2M3_ENST00000456743 Q8NG83 OR2M3 Olfactory receptor 2M3 chr1 Not Cancer Driver No 230-237 8 1.61e-03 0.0 21 10.66 197 - COAD, STAD, SARC, LUSC, GBM, UCEC, LUAD, KIRC, READ, SKCM
PTPN22 Q9Y2R2 PTPN22 Tyrosine-protein phosphatase non-receptor type 22 chr1 Not Cancer Driver No 690-693 4 1.61e-03 100.0 9 6.34 142 SKCM SKCM, BRCA
OR5D13 Q8NGL4 OR5D13 Olfactory receptor 5D13 chr11 Not Cancer Driver No 225-239 15 1.61e-03 0.0 39 20.63 189 - HNSC, LGG, STAD, UCEC, LUAD, LIHC, GBM, BRCA, LUSC, SKCM, BLCA
PRAMEF11 O60813 PRAMEF11 PRAME family member 11 chr1 Not Cancer Driver No 393-400 8 1.61e-03 0.0 14 8.86 158 LUAD, SKCM LUAD, LGG, SKCM, CESC, GBM, KIRC
CNTNAP4 Q9C0A0 CNTNAP4 Contactin-associated protein-like 4 chr16 Not Cancer Driver No 712-754 43 1.61e-03 0.0 42 10.12 415 SKCM SKCM, STAD, COAD, BLCA, LUSC, UCEC, OV, PRAD, LUAD, CESC, READ
LYNX1-SLURP2 P0DP58-2 LYNX1-SLURP2 Isoform 2 of Ly-6/neurotoxin-like protein 1 chr8 Not Cancer Driver No 108-125 18 1.63e-03 100.0 10 43.48 23 GBM LUSC, GBM, STAD, BRCA, SKCM
CYP21A2_ENST00000643666 P08686 CYP21A2 Steroid 21-hydroxylase chr6 Not Cancer Driver No 302-356 55 1.64e-03 12.73 23 32.86 70 SKCM CESC, COAD, SKCM, STAD, BLCA, LUAD, LUSC, KIRC, PRAD, UCEC, OV
ATXN2L_ENST00000336783 Q8WWM7 ATXN2L Ataxin-2-like protein chr16 Not Cancer Driver No 347-411 65 1.64e-03 100.0 23 16.91 136 - COAD, HNSC, SKCM, LUAD, GBM, BLCA, BRCA, THCA, LUSC, KIRC
FSIP2 Q5CZC0 FSIP2 Fibrous sheath-interacting protein 2 chr2 Not Cancer Driver No 5750-5812 63 1.66e-03 100.0 16 4.01 399 - SKCM, BRCA, COAD, UCEC, LIHC, SARC, OV, STAD
CACNG8 Q8WXS5 CACNG8 Voltage-dependent calcium channel gamma-8 subunit chr19 Not Cancer Driver No 63-75 13 1.66e-03 100.0 12 25.53 47 - LUSC, HNSC, COAD, CESC, PRAD, SKCM, LGG
OR4C16 Q8NGL9 OR4C16 Olfactory receptor 4C16 chr11 Not Cancer Driver No 31-31 1 1.66e-03 0.0 10 6.99 143 - STAD, CESC, HNSC, LGG, PRAD, LUAD, GBM
SPOCK3_ENST00000511531 Q9BQ16 SPOCK3 Testican-3 chr4 Not Cancer Driver No 394-434 41 1.66e-03 100.0 35 26.52 132 SKCM SKCM, KIRC, KICH, READ, LUAD, CESC, UCEC, BLCA, HNSC
NETO1 Q8TDF5 NETO1 Neuropilin and tolloid-like protein 1 chr18 Not Cancer Driver No 140-151 12 1.66e-03 0.0 17 9.14 186 SKCM KIRC, LUSC, GBM, LUAD, SKCM, HNSC
TPTE2 Q6XPS3 TPTE2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 38-43 6 1.67e-03 100.0 17 8.1 210 - STAD, SKCM, GBM, PRAD, COAD, READ, KIRC
TCFL5 Q9UL49 TCFL5 Transcription factor-like 5 protein chr20 Not Cancer Driver No 318-391 74 1.67e-03 100.0 23 42.59 54 - BLCA, COAD, SKCM, STAD, BRCA, LGG, HNSC, LIHC, READ, UCEC, LUAD
TNXB_ENST00000375244 P22105 TNXB Tenascin-X chr6 Not Cancer Driver No 1965-2038 74 1.67e-03 100.0 33 4.95 666 SKCM LUSC, HNSC, STAD, SKCM, BRCA, BLCA, COAD, LUAD, LIHC
ATP1A2 P50993 ATP1A2 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 Not Cancer Driver No 999-1012 14 1.68e-03 0.0 14 6.09 230 - LAML, HNSC, LUSC, OV, UCEC, SARC, SKCM, STAD, BLCA, BRCA, COAD
TBX18 O95935 TBX18 T-box transcription factor TBX18 chr6 Not Cancer Driver No 395-460 66 1.68e-03 100.0 36 22.36 161 - BRCA, LIHC, OV, KIRC, STAD, LUSC, UCEC, HNSC, DLBC, BLCA, SKCM, LUAD
STON1 Q9Y6Q2 STON1 Stonin-1 chr2 Not Cancer Driver No 564-576 13 1.69e-03 0.0 10 6.9 145 SKCM READ, LUAD, KIRC, SKCM, BLCA, COAD, HNSC
RCAN3_ENST00000538532 Q9UKA8 RCAN3 Calcipressin-3 chr1 Not Cancer Driver No 126-163 38 1.71e-03 77.5 20 55.56 36 SKCM HNSC, PAAD, SKCM, UCEC, GBM, LIHC
ADAMTS18 Q8TE60 ADAMTS18 A disintegrin and metalloproteinase with thrombospondin motifs 18 chr16 Not Cancer Driver No 216-220 5 1.71e-03 100.0 7 1.8 388 SKCM, OV, LUAD SKCM, OV, LUAD
HNRNPCL1 O60812 HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 1 chr1 Not Cancer Driver No 86-100 15 1.71e-03 86.67 24 16.9 142 SKCM KIRC, SKCM, STAD, BLCA, PRAD, LUSC, GBM
DHX9 Q08211 DHX9 ATP-dependent RNA helicase A chr1 Compendium Yes 40-40 1 1.72e-03 0.0 9 4.95 182 LUSC LUSC, KIRC, UCEC, SKCM, LUAD
PACSIN1_ENST00000244458 Q9BY11 PACSIN1 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 Not Cancer Driver No 380-391 12 1.72e-03 66.67 11 19.64 56 SKCM BRCA, PRAD, STAD, BLCA, SKCM, UCEC, LUSC, LUAD
MUC3A Q02505 MUC3A Mucin-3A chr7 Not Cancer Driver No 2869-2913 45 1.72e-03 100.0 15 6.76 222 - SKCM, BRCA, LUAD, BLCA, LUSC, STAD, GBM
PCDHGB3 Q9Y5G1 PCDHGB3 Protocadherin gamma-B3 chr5 Not Cancer Driver No 503-521 19 1.72e-03 0.0 18 7.69 234 UCEC UCEC, HNSC, GBM, SKCM, READ, STAD, BRCA, COAD, BLCA
ABCC12 Q96J65 ABCC12 ATP-binding cassette sub-family C member 12 chr16 Not Cancer Driver No 607-621 15 1.73e-03 0.0 17 6.75 252 LUSC UCEC, LUAD, HNSC, KIRC, STAD, SKCM, LUSC, SARC
CORIN Q9Y5Q5 CORIN Atrial natriuretic peptide-converting enzyme chr4 Not Cancer Driver No 262-264 3 1.73e-03 100.0 9 4.27 211 SKCM SKCM
ERG_ENST00000288319 P11308 ERG Transcriptional regulator ERG chr21 Census, Compendium Yes 115-155 41 1.74e-03 39.02 23 24.21 95 GBM STAD, LUSC, BRCA, COAD, SKCM, THCA, GBM, LUAD, KIRC, DLBC
CLEC4D Q8WXI8 CLEC4D C-type lectin domain family 4 member D chr12 Not Cancer Driver No 153-175 23 1.76e-03 0.0 18 30.51 59 - LIHC, UCEC, HNSC, LGG, KIRC, LUSC, SARC, CESC, OV, COAD, SKCM
TMEM131 Q92545 TMEM131 Transmembrane protein 131 chr2 Not Cancer Driver No 1319-1323 5 1.77e-03 100.0 9 3.46 260 LUSC BLCA, CESC, UCEC, LUSC, HNSC
PIK3C2B O00750 PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta chr1 Not Cancer Driver No 41-43 3 1.78e-03 100.0 9 3.72 242 GBM GBM, LUAD
PEAR1 Q5VY43 PEAR1 Platelet endothelial aggregation receptor 1 chr1 Not Cancer Driver No 41-96 56 1.78e-03 35.71 21 13.29 158 - GBM, COAD, CESC, THCA, READ, LIHC, BRCA, LAML, LUSC, STAD, SKCM, LUAD
SAC3D1 F8WC89 SAC3D1 SAC3 domain-containing protein 1 chr11 Not Cancer Driver No 313-357 45 1.78e-03 100.0 15 60.0 25 - GBM, BRCA, PAAD, BLCA, SKCM, LUSC, UCEC, HNSC, COAD, STAD
ATXN3 P54252 ATXN3 Ataxin-3 chr14 Not Cancer Driver No 295-306 12 1.80e-03 100.0 3 6.25 48 GBM, COAD KIRC, GBM, COAD
CASR_ENST00000638421 P41180 CASR Extracellular calcium-sensing receptor chr3 Not Cancer Driver No 886-896 11 1.80e-03 90.91 17 5.52 308 - UCEC, STAD, BRCA, GBM, BLCA, COAD, LUAD, DLBC, LUSC
MZT2B_ENST00000281871 Q6NZ67 MZT2B Mitotic-spindle organizing protein 2B chr2 Not Cancer Driver No 107-155 49 1.80e-03 100.0 13 92.86 14 - OV, STAD, SKCM, BRCA, READ, LUAD, UCEC, BLCA, PRAD, LUSC
NDUFC2 O95298 NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 chr11 Not Cancer Driver No 59-59 1 1.80e-03 0.0 4 25.0 16 LUSC, UCEC, SKCM, CESC LUSC, UCEC, SKCM, CESC
NLRP12_ENST00000324134 P59046 NLRP12 NACHT, LRR and PYD domains-containing protein 12 chr19 Not Cancer Driver No 835-836 2 1.82e-03 0.0 9 2.88 312 SKCM LUSC, BRCA, SKCM, SARC
POTEH Q6S545 POTEH POTE ankyrin domain family member H chr22 Not Cancer Driver No 132-194 63 1.82e-03 44.62 47 21.17 222 LUAD STAD, GBM, BRCA, LUSC, LIHC, SKCM, COAD, LUAD, CESC, SARC, READ, KIRC, PRAD, HNSC
CENPS Q8N2Z9 CENPS Centromere protein S chr1 Not Cancer Driver No 24-52 29 1.82e-03 0.0 8 50.0 16 OV HNSC, LUSC, KIRC, STAD, OV, LGG
HIVEP3 Q5T1R4 HIVEP3 Transcription factor HIVEP3 chr1 Not Cancer Driver No 2339-2339 1 1.83e-03 100.0 18 4.71 382 COAD, READ COAD, READ
MTOR P42345 MTOR Serine/threonine-protein kinase mTOR chr1 Census, Compendium Yes 1799-1799 1 1.84e-03 0.0 12 3.15 381 UCEC SKCM, CESC, UCEC, COAD, GBM
MYT1L Q9UL68 MYT1L Myelin transcription factor 1-like protein chr2 Not Cancer Driver No 9-18 10 1.86e-03 100.0 16 4.34 369 LUAD, SKCM PAAD, LUAD, BLCA, STAD, KIRC, SKCM, OV
PAPPA2 Q9BXP8 PAPPA2 Pappalysin-2 chr1 Not Cancer Driver No 605-619 15 1.86e-03 13.33 20 2.7 742 LUAD PRAD, COAD, SKCM, STAD, HNSC, BRCA, LUAD, LUSC
COL14A1 Q05707 COL14A1 Collagen alpha-1(XIV) chain chr8 Not Cancer Driver No 839-852 14 1.86e-03 0.0 16 3.93 407 - LUAD, SKCM, OV, BLCA, STAD, GBM, UCEC, HNSC, BRCA, LUSC
GALNT17 Q6IS24 GALNT17 Polypeptide N-acetylgalactosaminyltransferase 17 chr7 Not Cancer Driver No 100-107 8 1.87e-03 0.0 16 5.25 305 SKCM READ, LIHC, LUAD, STAD, LGG, SKCM, UCEC
CEP350 Q5VT06 CEP350 Centrosome-associated protein 350 chr1 Not Cancer Driver No 894-903 10 1.88e-03 100.0 1 0.26 390 COAD COAD, BRCA
PXDNL A1KZ92 PXDNL Probable oxidoreductase PXDNL chr8 Not Cancer Driver No 945-945 1 1.88e-03 100.0 9 1.6 564 COAD STAD, LUSC, BLCA, COAD
SNED1 Q8TER0 SNED1 Sushi, nidogen and EGF-like domain-containing protein 1 chr2 Not Cancer Driver No 287-293 7 1.88e-03 100.0 1 0.68 148 READ READ, SKCM
TMEM196 Q5HYL7 TMEM196 Transmembrane protein 196 chr7 Not Cancer Driver No 86-127 42 1.88e-03 21.43 22 61.11 36 LUAD HNSC, CESC, PRAD, GBM, SKCM, UCEC, STAD, LUSC, LUAD, KIRC
OTOP1 Q7RTM1 OTOP1 Proton channel OTOP1 chr4 Not Cancer Driver No 104-109 6 1.88e-03 0.0 1 0.94 106 OV, UCEC OV, LUSC, UCEC
MEF2D Q14814 MEF2D Myocyte-specific enhancer factor 2D chr1 Not Cancer Driver No 455-480 26 1.88e-03 100.0 16 21.33 75 OV, SKCM PAAD, OV, STAD, SKCM, LUAD, UCEC
MSH3 P20585 MSH3 DNA mismatch repair protein Msh3 chr5 Not Cancer Driver No 57-69 13 1.88e-03 100.0 2 1.98 101 READ READ
PCNT O95613 PCNT Pericentrin chr21 Not Cancer Driver No 162-179 18 1.88e-03 100.0 18 3.91 460 - LUSC, LGG, UCEC, PRAD, BLCA, SKCM, KIRC, LUAD
LRP1 Q07954 LRP1 Prolow-density lipoprotein receptor-related protein 1 chr12 Not Cancer Driver No 1058-1059 2 1.89e-03 100.0 9 1.36 664 PRAD, KIRC PRAD, UCEC, SKCM, KIRC
PLEC Q15149 PLEC Plectin chr8 Not Cancer Driver No 1386-1386 1 1.89e-03 100.0 22 3.08 715 READ READ
TCERG1L Q5VWI1 TCERG1L Transcription elongation regulator 1-like protein chr10 Not Cancer Driver No 348-393 46 1.89e-03 56.52 25 21.01 119 - BRCA, LUAD, UCEC, LUSC, LGG, SARC, OV, SKCM, STAD, THCA, COAD
ADGRL3 Q9HAR2 ADGRL3 Adhesion G protein-coupled receptor L3 chr4 Not Cancer Driver No 818-832 15 1.90e-03 0.0 18 4.06 443 - LUSC, COAD, BRCA, STAD, LUAD, BLCA, KIRC, PRAD, SKCM, HNSC, LGG
POU4F2 Q12837 POU4F2 POU domain, class 4, transcription factor 2 chr4 Not Cancer Driver No 330-390 61 1.91e-03 30.65 39 29.32 133 - LUSC, UCEC, BLCA, GBM, CESC, COAD, STAD, READ, LUAD, OV, HNSC, SKCM, BRCA
RYR3 Q15413 RYR3 Ryanodine receptor 3 chr15 Not Cancer Driver No 1002-1038 37 1.91e-03 100.0 16 1.47 1091 LUSC, OV READ, LUSC, CESC, OV, HNSC, LIHC, SKCM, LUAD, UCEC
BRD7_ENST00000394688 Q9NPI1 BRD7 Bromodomain-containing protein 7 chr16 Compendium Yes 427-461 35 1.92e-03 63.89 15 18.07 83 - BLCA, LIHC, SKCM, LUSC, KIRC, BRCA, LUAD, STAD
FABP1 P07148 FABP1 Fatty acid-binding protein, liver chr2 Not Cancer Driver No 58-69 12 1.93e-03 0.0 12 35.29 34 SKCM, UCEC BRCA, SKCM, PRAD, UCEC, GBM, KIRC
ZNF415_ENST00000601493 Q09FC8-3 ZNF415 Isoform 3 of Zinc finger protein 415 chr19 Not Cancer Driver No 267-275 9 1.94e-03 100.0 14 19.72 71 OV BRCA, HNSC, BLCA, LUAD, SKCM, OV
ANKHD1 Q8IWZ3 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1503-1514 12 1.94e-03 100.0 7 2.39 293 BLCA BLCA, UCEC, SKCM, HNSC, STAD, GBM
ANKHD1 Q8IWZ3 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1841-1853 13 1.94e-03 100.0 7 2.39 293 SKCM UCEC, BLCA, SKCM, BRCA, CESC
CHRNA7_ENST00000306901 P36544 CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 chr15 Not Cancer Driver No 371-388 18 1.94e-03 100.0 13 18.31 71 - PAAD, STAD, SKCM, LUAD, SARC, UCEC, BLCA, HNSC, LUSC
YOD1 Q5VVQ6 YOD1 Ubiquitin thioesterase OTU1 chr1 Not Cancer Driver No 164-186 23 1.95e-03 0.0 11 36.67 30 GBM, UCEC SARC, BLCA, GBM, STAD, UCEC, BRCA
THSD7B Q9C0I4 THSD7B Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1439-1445 7 1.97e-03 71.43 16 2.43 659 SKCM LUSC, BRCA, BLCA, LUAD, SKCM
RBM44_ENST00000409864 Q6ZP01 RBM44 RNA-binding protein 44 chr2 Not Cancer Driver No 423-483 61 1.98e-03 100.0 19 13.48 141 LUAD, BLCA LIHC, GBM, READ, LUAD, BRCA, BLCA, HNSC, STAD
SMARCB1_ENST00000644036 Q12824 SMARCB1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 368-377 10 2.00e-03 100.0 12 18.75 64 COAD LGG, OV, COAD, UCEC, STAD, BLCA, KIRC
SPTBN4_ENST00000598249 Q9H254 SPTBN4 Spectrin beta chain, non-erythrocytic 4 chr19 Not Cancer Driver No 1805-1876 72 2.00e-03 31.51 26 8.25 315 - BRCA, LUSC, STAD, KIRC, BLCA, SARC, UCEC, LUAD, GBM, SKCM
MPRIP_ENST00000341712 Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 572-611 40 2.01e-03 92.5 10 8.33 120 OV OV, SKCM, HNSC, LUSC, COAD, UCEC, STAD
CUEDC2 Q9H467 CUEDC2 CUE domain-containing protein 2 chr10 Not Cancer Driver No 45-45 1 2.01e-03 100.0 8 21.62 37 CESC, BLCA, SKCM CESC, BLCA, SKCM, HNSC, STAD
SOWAHA Q2M3V2 SOWAHA Ankyrin repeat domain-containing protein SOWAHA chr5 Not Cancer Driver No 124-131 8 2.01e-03 100.0 8 28.57 28 COAD, READ COAD, READ
THAP8 Q8NA92 THAP8 THAP domain-containing protein 8 chr19 Not Cancer Driver No 185-189 5 2.01e-03 0.0 17 40.48 42 COAD, READ COAD, CESC, READ
VWC2 Q2TAL6 VWC2 Brorin chr7 Not Cancer Driver No 237-284 48 2.02e-03 0.0 20 36.36 55 SKCM, LUAD STAD, LIHC, CESC, COAD, SKCM, LUAD, HNSC, LUSC, UCEC
FAT4 Q6V0I7 FAT4 Protocadherin Fat 4 chr4 Census, Compendium Yes 2503-2514 12 2.02e-03 100.0 16 1.21 1326 SKCM LUSC, READ, STAD, UCEC, HNSC, BRCA, SKCM
LILRB3_ENST00000391750 C9JWL8 LILRB3 Leukocyte immunoglobulin-like receptor subfamily B member 3 chr19 Not Cancer Driver No 524-590 67 2.02e-03 100.0 28 30.43 92 - SKCM, STAD, CESC, UCEC, KIRC, LIHC, READ, OV, BLCA, GBM, LUAD, PRAD
PRSS35 Q8N3Z0 PRSS35 Inactive serine protease 35 chr6 Not Cancer Driver No 318-364 47 2.02e-03 0.0 29 29.9 97 SKCM BLCA, LUAD, SKCM, COAD, BRCA, LUSC, CESC, STAD, GBM, UCEC
SLC22A11 Q9NSA0 SLC22A11 Solute carrier family 22 member 11 chr11 Not Cancer Driver No 191-237 47 2.07e-03 0.0 21 24.42 86 - PAAD, GBM, STAD, BRCA, REO, READ, SKCM, SARC, LUAD, UCEC
SLC16A8 O95907 SLC16A8 Monocarboxylate transporter 3 chr22 Not Cancer Driver No 235-235 1 2.08e-03 100.0 16 36.36 44 COAD, READ OAD, COAD, READ
TBC1D2 Q9BYX2 TBC1D2 TBC1 domain family member 2A chr9 Not Cancer Driver No 141-184 44 2.10e-03 95.45 17 15.74 108 SKCM UCEC, LUSC, BLCA, BRCA, GBM, LUAD, OV, STAD, SKCM
FLG P20930 FLG Filaggrin chr1 Not Cancer Driver No 1463-1475 13 2.10e-03 100.0 22 1.3 1696 LUAD, SKCM LUSC, HNSC, LUAD, LGG, SKCM, COAD, READ
RYR1 P21817 RYR1 Ryanodine receptor 1 chr19 Not Cancer Driver No 1815-1830 16 2.10e-03 100.0 17 1.68 1011 LUAD OV, HNSC, PAAD, LIHC, CESC, PRAD, LUAD, LUSC, STAD, THCA
PRKCG P05129 PRKCG Protein kinase C gamma type chr19 Not Cancer Driver No 180-221 42 2.11e-03 0.0 28 16.0 175 SKCM OV, HNSC, KICH, GBM, THCA, READ, STAD, BRCA, LUSC, LUAD, UCEC, SKCM
GRIN3B O60391 GRIN3B Glutamate receptor ionotropic, NMDA 3B chr19 Not Cancer Driver No 560-604 45 2.12e-03 23.4 17 15.89 107 - LGG, LUSC, SARC, STAD, LUAD, BRCA, SKCM, PAAD, HNSC, COAD
EFCC1 Q9HA90 EFCC1 EF-hand and coiled-coil domain-containing protein 1 chr3 Not Cancer Driver No 579-585 7 2.13e-03 100.0 8 24.24 33 BLCA, LUSC BLCA, BRCA, KIRC, LUAD, LUSC
VSIG10L Q86VR7 VSIG10L V-set and immunoglobulin domain-containing protein 10-like chr19 Not Cancer Driver No 356-356 1 2.13e-03 0.0 16 32.0 50 COAD, READ COAD, READ
ACSL3 O95573 ACSL3 Fatty acid CoA ligase Acsl3 chr2 Census, Compendium Yes 181-188 8 2.14e-03 0.0 11 12.22 90 LAML, KIRC LIHC, LAML, GBM, KIRC
PSD A5PKW4 PSD PH and SEC7 domain-containing protein 1 chr10 Not Cancer Driver No 453-506 54 2.17e-03 100.0 27 15.52 174 - UCEC, KIRC, LUSC, STAD, LIHC, LUAD, PAAD, SKCM, BLCA, COAD, PRAD, BRCA, HNSC
RHOXF2 Q9BQY4 RHOXF2 Rhox homeobox family member 2 chrX Not Cancer Driver No 108-156 49 2.18e-03 64.0 20 62.5 32 - UCEC, CESC, LUAD, COAD, SKCM, SARC, STAD, OV, LUSC
FBXO15 Q8NCQ5 FBXO15 F-box only protein 15 chr18 Not Cancer Driver No 435-451 17 2.19e-03 5.88 14 16.28 86 SKCM UCEC, LUSC, SKCM, READ
HSD3B2_ENST00000369416 P26439 HSD3B2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 chr1 Not Cancer Driver No 72-79 8 2.19e-03 0.0 11 13.1 84 LUAD BLCA, GBM, SKCM, CESC, LUAD, BRCA
PTCHD3_ENST00000622555 Q3KNS1-2 PTCHD3 Isoform 2 of Patched domain-containing protein 3 chr10 Not Cancer Driver No 86-95 10 2.19e-03 100.0 2 1.5 133 COAD, READ COAD, BLCA, READ
CSH1 P0DML2 CSH1 Chorionic somatomammotropin hormone 1 chr17 Not Cancer Driver No 200-212 13 2.19e-03 0.0 12 36.36 33 - BLCA, SKCM, LUSC, LIHC, STAD, OV, LGG, HNSC
SVOPL Q8N434 SVOPL Putative transporter SVOPL chr7 Not Cancer Driver No 424-433 10 2.20e-03 0.0 12 12.0 100 SKCM SKCM, UCEC, COAD, GBM, HNSC, BRCA, CESC
ZC3H12A Q5D1E8 ZC3H12A Endoribonuclease ZC3H12A chr1 Not Cancer Driver No 206-215 10 2.20e-03 0.0 9 10.0 90 - SKCM, COAD, KIRC, READ, BRCA, CESC, PAAD, STAD, KICH, DLBC
TP53TG3D_ENST00000569631 H3BT92 TP53TG3D TP53-target gene 3 protein chr16 Not Cancer Driver No 28-61 34 2.21e-03 100.0 15 88.24 17 - CESC, SKCM, COAD, UCEC, LUAD, LUSC
ACTB_ENST00000646664 P60709 ACTB Actin, cytoplasmic 1 chr7 Not Cancer Driver No 334-348 15 2.24e-03 0.0 19 16.96 112 - CESC, SKCM, STAD, HNSC, BLCA, LUAD, LUSC, KIRC, BRCA
ECE1 P42892 ECE1 Endothelin-converting enzyme 1 chr1 Not Cancer Driver No 604-635 32 2.24e-03 0.0 19 15.97 119 - STAD, SKCM, UCEC, OV, LUSC, BLCA, READ, BRCA
KCNK15 Q9H427 KCNK15 Potassium channel subfamily K member 15 chr20 Not Cancer Driver No 95-137 43 2.25e-03 0.0 22 37.29 59 UCEC KIRC, HNSC, STAD, SKCM, COAD, UCEC, LIHC, LUSC, BRCA, READ
PLP1 P60201 PLP1 Myelin proteolipid protein chrX Not Cancer Driver No 103-143 41 2.26e-03 100.0 21 42.86 49 - THCA, LUAD, LIHC, HNSC, LUSC, STAD, SKCM, COAD, READ, SARC, OV
STT3B Q8TCJ2 STT3B Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 327-357 31 2.26e-03 0.0 8 13.33 60 OV KIRC, LIHC, SKCM, READ, STAD, BRCA, HNSC, OV
CD1C P29017 CD1C T-cell surface glycoprotein CD1c chr1 Not Cancer Driver No 83-97 15 2.27e-03 0.0 21 16.54 127 SKCM PRAD, LUAD, SARC, SKCM, BRCA, BLCA, UCEC
CTIF_ENST00000256413 O43310 CTIF CBP80/20-dependent translation initiation factor chr18 Not Cancer Driver No 265-275 11 2.28e-03 100.0 12 12.37 97 OV LUAD, HNSC, SKCM, OV, LGG, LUSC, STAD, BRCA
BMP6 P22004 BMP6 Bone morphogenetic protein 6 chr6 Not Cancer Driver No 111-118 8 2.29e-03 100.0 10 9.8 102 - KIRC, STAD, PRAD, HNSC, SARC, LUAD, READ
CBWD3 Q5JTY5 CBWD3 COBW domain-containing protein 3 chr9 Not Cancer Driver No 144-155 12 2.29e-03 25.0 7 43.75 16 - READ, BLCA, PRAD, KIRC, HNSC, CESC, DLBC
DNAJC1 Q96KC8 DNAJC1 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 392-445 54 2.29e-03 100.0 17 27.87 61 CESC STAD, BLCA, OV, LIHC, SKCM, HNSC, UCEC, READ, CESC, LUAD
TFR2_ENST00000223051 Q9UP52 TFR2 Transferrin receptor protein 2 chr7 Not Cancer Driver No 383-393 11 2.29e-03 27.27 11 11.7 94 BLCA LUAD, BLCA, SKCM, KIRC, GBM
GRIN2D O15399 GRIN2D Glutamate receptor ionotropic, NMDA 2D chr19 Not Cancer Driver No 696-747 52 2.30e-03 1.92 17 13.6 125 SKCM HNSC, SARC, LUAD, BLCA, UCEC, OV, LUSC, COAD, SKCM
TNFRSF8 P28908 TNFRSF8 Tumor necrosis factor receptor superfamily member 8 chr1 Not Cancer Driver No 26-34 9 2.30e-03 44.44 12 12.63 95 LUAD, SKCM LUAD, SKCM, STAD, LAML, HNSC
BCAM P50895 BCAM Basal cell adhesion molecule chr19 Not Cancer Driver No 580-588 9 2.31e-03 100.0 13 11.71 111 STAD KIRC, SKCM, LUAD, STAD, READ, GBM, CESC
OPRM1_ENST00000330432 P35372 OPRM1 Mu-type opioid receptor chr6 Not Cancer Driver No 367-373 7 2.31e-03 100.0 17 15.74 108 - LIHC, KIRC, SKCM, BRCA, GBM, HNSC, LUSC, LUAD
BOC_ENST00000355385 Q9BWV1 BOC Brother of CDO chr3 Not Cancer Driver No 13-25 13 2.31e-03 100.0 3 1.66 181 GBM HNSC, GBM, COAD
SORL1 Q92673 SORL1 Sortilin-related receptor chr11 Not Cancer Driver No 2152-2214 63 2.33e-03 100.0 27 7.2 375 SKCM LUSC, SKCM, KIRC, LUAD, UCEC, BLCA, CESC, OV, BRCA
HBA2 P69905 HBA2 Hemoglobin subunit alpha chr16 Not Cancer Driver No 109-138 30 2.33e-03 0.0 8 88.89 9 BRCA, LUAD, HNSC LUSC, BRCA, LUAD, HNSC
PPP1R3G B7ZBB8 PPP1R3G Protein phosphatase 1 regulatory subunit 3G chr6 Not Cancer Driver No 280-280 1 2.33e-03 100.0 14 66.67 21 COAD, READ COAD, READ
TBK1 Q9UHD2 TBK1 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 102-109 8 2.33e-03 0.0 12 11.76 102 GBM GBM, BLCA
MYC_ENST00000377970 P01106 MYC Myc proto-oncogene protein chr8 Census, Compendium Yes 139-149 11 2.34e-03 100.0 13 16.25 80 HNSC KIRC, LUAD, READ, COAD, SKCM, CESC, BLCA, HNSC, LUSC
SLC4A10 Q6U841 SLC4A10 Sodium-driven chloride bicarbonate exchanger chr2 Not Cancer Driver No 399-447 49 2.34e-03 38.78 29 13.12 221 SKCM READ, OV, LUAD, UCEC, LUSC, SKCM, HNSC, STAD
NYX Q9GZU5 NYX Nyctalopin chrX Not Cancer Driver No 313-351 39 2.36e-03 2.56 14 28.57 49 - LGG, HNSC, BRCA, COAD, LUSC, LUAD, GBM, UCEC, SKCM
TMC4 Q7Z404 TMC4 Transmembrane channel-like protein 4 chr19 Not Cancer Driver No 14-20 7 2.36e-03 100.0 12 12.0 100 BLCA SKCM, BLCA, BRCA
EXD3 Q8N9H8 EXD3 Exonuclease mut-7 homolog chr9 Not Cancer Driver No 653-664 12 2.37e-03 23.08 12 10.91 110 BLCA UCEC, STAD, COAD, BLCA, LUAD, READ, SKCM
STK11 Q15831 STK11 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 239-251 13 2.37e-03 0.0 13 17.11 76 LUAD THCA, SKCM, LUAD
PFKP Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type chr10 Not Cancer Driver No 43-51 9 2.38e-03 0.0 14 10.53 133 UCEC LUAD, SKCM, STAD, COAD, UCEC
INAVA_ENST00000367342 Q3KP66 INAVA Innate immunity activator protein chr1 Not Cancer Driver No 444-452 9 2.40e-03 100.0 19 14.29 133 BLCA LUAD, STAD, BLCA
MDH2 P40926 MDH2 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 9-9 1 2.42e-03 100.0 16 34.04 47 COAD, READ COAD, READ
NR1H4 Q96RI1 NR1H4 Bile acid receptor chr12 Not Cancer Driver No 65-100 36 2.45e-03 100.0 23 20.54 112 OV, SKCM LUSC, OV, BLCA, GBM, READ, SKCM, LUAD
TYSND1 Q2T9J0 TYSND1 Peroxisomal leader peptide-processing protease chr10 Not Cancer Driver No 65-65 1 2.46e-03 0.0 18 36.73 49 READ, COAD READ, COAD
FZD2 Q14332 FZD2 Frizzled-2 chr17 Not Cancer Driver No 425-464 40 2.46e-03 17.07 23 26.74 86 - STAD, KIRC, SKCM, CESC, LUSC, LUAD, UCEC, HNSC, OV, BRCA, COAD, BLCA
NADK_ENST00000341991 O95544 NADK NAD kinase chr1 Not Cancer Driver No 430-445 16 2.47e-03 68.75 2 3.28 61 UCEC, OV, COAD UCEC, OV, COAD
PLCL1 Q15111 PLCL1 Inactive phospholipase C-like protein 1 chr2 Not Cancer Driver No 800-859 60 2.48e-03 16.67 36 13.79 261 - UCEC, BLCA, LIHC, LGG, HNSC, LUAD, LUSC, DLBC, KIRC, STAD, SKCM, GBM
WASHC2A Q641Q2 WASHC2A WASH complex subunit 2A chr10 Not Cancer Driver No 379-379 1 2.49e-03 100.0 8 16.67 48 BRCA BRCA, CESC
PDZRN4 Q6ZMN7 PDZRN4 PDZ domain-containing RING finger protein 4 chr12 Not Cancer Driver No 885-939 55 2.50e-03 74.55 30 11.36 264 SKCM LUSC, KIRC, COAD, SKCM, HNSC, READ, BRCA, LUAD
SLC6A5 Q9Y345 SLC6A5 Sodium- and chloride-dependent glycine transporter 2 chr11 Not Cancer Driver No 737-781 45 2.50e-03 10.87 26 13.61 191 SKCM SKCM, KIRC, CESC, BRCA, PRAD, LUSC, LUAD, READ, BLCA, PAAD
CD7 P09564 CD7 T-cell antigen CD7 chr17 Not Cancer Driver No 172-180 9 2.50e-03 88.89 0 0.0 36 READ, COAD READ, COAD
GOLGA6L7 A0A1B0GV03 GOLGA6L7 Golgin subfamily A member 6-like protein 7 chr15 Not Cancer Driver No 243-248 6 2.50e-03 100.0 0 0.0 27 UCEC UCEC
PRSS16 Q9NQE7 PRSS16 Thymus-specific serine protease chr6 Not Cancer Driver No 507-511 5 2.50e-03 0.0 0 0.0 85 BLCA, OV BLCA, OV
RBM14-RBM4 Q96PK6-5 RBM14-RBM4 Isoform 5 of RNA-binding protein 14 chr11 Not Cancer Driver No 264-270 7 2.50e-03 100.0 1 2.44 41 BLCA BLCA
RBM4_ENST00000310092 Q9BWF3 RBM4 RNA-binding protein 4 chr11 Not Cancer Driver No 289-295 7 2.50e-03 100.0 1 2.5 40 BLCA BLCA
RUNX2_ENST00000647337 Q13950 RUNX2 Runt-related transcription factor 2 chr6 Not Cancer Driver No 84-89 6 2.50e-03 100.0 0 0.0 83 READ READ
MRTFA_ENST00000407029 Q969V6 MRTFA Myocardin-related transcription factor A chr22 Census Yes 253-262 10 2.50e-03 50.0 12 9.02 133 GBM SKCM, UCEC, HNSC, LUAD, GBM
SRGAP2 O75044 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 184-219 36 2.50e-03 91.67 18 14.4 125 UCEC PRAD, LUSC, CESC, COAD, BRCA, KIRC, BLCA, UCEC, SKCM
KRTAP1-1 Q07627 KRTAP1-1 Keratin-associated protein 1-1 chr17 Not Cancer Driver No 34-38 5 2.52e-03 100.0 10 35.71 28 KIRC, LUAD KIRC, LUAD, BLCA
DMRT3 Q9NQL9 DMRT3 Doublesex- and mab-3-related transcription factor 3 chr9 Not Cancer Driver No 426-438 13 2.53e-03 100.0 13 13.0 100 - STAD, GBM, BLCA, LUSC, READ, LGG, LUAD, HNSC, COAD, SKCM
SPAG16 Q8N0X2 SPAG16 Sperm-associated antigen 16 protein chr2 Not Cancer Driver No 433-440 8 2.56e-03 0.0 12 7.45 161 LUAD PRAD, READ, LUSC, BLCA, LUAD, SKCM, CESC
ECHS1 P30084 ECHS1 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 11-11 1 2.56e-03 100.0 20 32.79 61 COAD, READ COAD, READ
ESYT2_ENST00000613624 A0FGR8 ESYT2 Extended synaptotagmin-2 chr7 Not Cancer Driver No 342-406 65 2.56e-03 27.69 19 20.0 95 - BRCA, LUSC, LUAD, STAD, READ, BLCA, HNSC, CESC, SKCM, UCEC
LRRC37A3 O60309 LRRC37A3 Leucine-rich repeat-containing protein 37A3 chr17 Not Cancer Driver No 1264-1319 56 2.58e-03 100.0 21 12.43 169 - LGG, LIHC, LUSC, READ, SKCM, BLCA, LUAD, PRAD, UCEC, STAD
LHFPL1 Q86WI0 LHFPL1 LHFPL tetraspan subfamily member 1 protein chrX Not Cancer Driver No 69-69 1 2.59e-03 0.0 9 18.75 48 GBM, LGG GBM, KIRC, OV, LGG
STRADB Q9C0K7 STRADB STE20-related kinase adapter protein beta chr2 Not Cancer Driver No 407-409 3 2.59e-03 100.0 9 16.67 54 COAD BRCA, COAD
ZNF444 Q8N0Y2 ZNF444 Zinc finger protein 444 chr19 Not Cancer Driver No 104-134 31 2.60e-03 100.0 10 55.56 18 SKCM HNSC, SKCM, GBM, LUAD, LUSC, LAML
UNC119B A6NIH7 UNC119B Protein unc-119 homolog B chr12 Not Cancer Driver No 144-153 10 2.61e-03 0.0 10 28.57 35 - PRAD, BLCA, BRCA, SKCM, LAML, GBM, LUAD, KIRC
NFATC1 O95644 NFATC1 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 219-224 6 2.62e-03 100.0 11 6.21 177 SKCM PRAD, BLCA, UCEC, SKCM, COAD
SLC26A9_ENST00000367135 Q7LBE3 SLC26A9 Solute carrier family 26 member 9 chr1 Not Cancer Driver No 362-369 8 2.62e-03 0.0 11 6.59 167 - SKCM, CESC, OV, LUAD, GBM, BRCA, LUSC
SLC8A2 Q9UPR5 SLC8A2 Sodium/calcium exchanger 2 chr19 Not Cancer Driver No 69-127 59 2.63e-03 21.67 22 18.64 118 SKCM COAD, SKCM, UCEC, LUSC, STAD, LUAD, PAAD, KIRC, BLCA
OR11H1 Q8NG94 OR11H1 Olfactory receptor 11H1 chr22 Not Cancer Driver No 248-256 9 2.63e-03 0.0 16 13.22 121 - BLCA, LUAD, BRCA, GBM, COAD, SKCM, LUSC
POLR3B Q9NW08 POLR3B DNA-directed RNA polymerase III subunit RPC2 chr12 Not Cancer Driver No 361-372 12 2.63e-03 0.0 11 6.67 165 SKCM, KIRC SKCM, READ, KIRC, LGG, COAD, CESC, LUSC
FGD6 Q6ZV73 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 chr12 Not Cancer Driver No 307-349 43 2.63e-03 100.0 24 12.06 199 SKCM LGG, LUSC, BLCA, LUAD, SKCM, READ, STAD, SARC
L1TD1 Q5T7N2 L1TD1 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 409-420 12 2.63e-03 100.0 8 5.23 153 KIRC, REO SKCM, UCEC, KIRC, REO
INSM2 Q96T92 INSM2 Insulinoma-associated protein 2 chr14 Not Cancer Driver No 515-519 5 2.65e-03 100.0 8 16.0 50 UCEC, SKCM UCEC, LUSC, BLCA, KIRC, SKCM
PCDHA4 Q9UN74 PCDHA4 Protocadherin alpha-4 chr5 Not Cancer Driver No 630-650 21 2.67e-03 9.52 22 6.83 322 - STAD, COAD, BRCA, READ, LUSC, SKCM, DLBC, LUAD, UCEC
OR10G8 Q8NGN5 OR10G8 Olfactory receptor 10G8 chr11 Not Cancer Driver No 220-235 16 2.67e-03 0.0 23 14.29 161 - SKCM, COAD, UCEC, LGG, LUAD, HNSC, LUSC, STAD, PRAD, CESC
FBXL19 Q6PCT2 FBXL19 F-box/LRR-repeat protein 19 chr16 Not Cancer Driver No 319-373 55 2.67e-03 100.0 17 25.0 68 SKCM GBM, SKCM, LUSC, OV, BLCA, BRCA, LUAD, COAD, HNSC
NTN1 O95631 NTN1 Netrin-1 chr17 Not Cancer Driver No 348-397 50 2.68e-03 0.0 17 29.82 57 - HNSC, KIRC, COT, UCEC, SKCM, PRAD, GBM, LUSC, CESC, STAD
CD7 P09564 CD7 T-cell antigen CD7 chr17 Not Cancer Driver No 39-89 51 2.69e-03 0.0 19 52.78 36 SKCM LUSC, SKCM, GBM, STAD, UCEC, BLCA, READ
GABRA6 Q16445 GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 chr5 Not Cancer Driver No 22-33 12 2.69e-03 33.33 19 9.95 191 STAD BRCA, LUSC, STAD, HNSC, GBM, UCEC, SKCM, LIHC, LGG
ZNF560 Q96MR9 ZNF560 Zinc finger protein 560 chr19 Not Cancer Driver No 690-694 5 2.70e-03 100.0 15 6.91 217 SKCM LGG, BLCA, SKCM, LUAD
AP3S1 Q92572 AP3S1 AP-3 complex subunit sigma-1 chr5 Not Cancer Driver No 118-123 6 2.70e-03 0.0 10 28.57 35 BLCA CESC, BLCA
ARL4D P49703 ARL4D ADP-ribosylation factor-like protein 4D chr17 Not Cancer Driver No 39-46 8 2.70e-03 0.0 10 32.26 31 GBM HNSC, GBM, UCEC
DACH2 Q96NX9 DACH2 Dachshund homolog 2 chrX Not Cancer Driver No 554-556 3 2.71e-03 100.0 12 5.97 201 UCEC, KIRC LUSC, UCEC, STAD, KIRC
NSMCE3 Q96MG7 NSMCE3 Non-structural maintenance of chromosomes element 3 homolog chr15 Not Cancer Driver No 199-238 40 2.72e-03 2.5 14 42.42 33 - KIRC, SKCM, UCEC, LGG, STAD, HNSC, BLCA, OV, READ, LUSC
RAPGEF6_ENST00000509018 Q8TEU7 RAPGEF6 Rap guanine nucleotide exchange factor 6 chr5 Not Cancer Driver No 389-403 15 2.72e-03 6.25 11 5.73 192 - PRAD, COAD, BLCA, LUAD, OV, SKCM, HNSC
MROH5 Q6ZUA9 MROH5 Maestro heat-like repeat family member 5 chr8 Not Cancer Driver No 1130-1184 55 2.72e-03 5.45 22 11.46 192 BLCA STAD, HNSC, UCEC, KIRC, BLCA, LUAD, LIHC, COAD, SKCM, OV
AC008695.1 E9PCH4 AC008695.1 Uncharacterized protein chr5 Not Cancer Driver No 439-453 15 2.74e-03 100.0 11 5.53 199 - SKCM, HNSC, COAD, OV, BLCA, LUAD, PRAD
MBD3L3 A6NE82 MBD3L3 Putative methyl-CpG-binding domain protein 3-like 3 chr19 Not Cancer Driver No 124-138 15 2.74e-03 100.0 11 73.33 15 LAML, BRCA LAML, BRCA, UCEC, OV, BLCA
GNAQ P50148 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 96-96 1 2.76e-03 0.0 8 14.04 57 BLCA PRAD, SKCM, BLCA
C10orf71 Q711Q0 CEFIP Cardiac-enriched FHL2-interacting protein chr10 Not Cancer Driver No 86-96 11 2.76e-03 100.0 12 5.02 239 STAD SKCM, GBM, LUAD, STAD, COAD, LUSC
DBH P09172 DBH Dopamine beta-hydroxylase chr9 Not Cancer Driver No 265-276 12 2.78e-03 0.0 13 10.16 128 SKCM COAD, PRAD, GBM, BRCA, UCEC, LGG, STAD, SKCM
NSUN2 Q08J23 NSUN2 RNA cytosine C(5)-methyltransferase NSUN2 chr5 Not Cancer Driver No 200-255 56 2.78e-03 1.75 24 21.24 113 - BLCA, HNSC, GBM, LUSC, UCEC, SKCM, KIRC, LUAD, STAD, READ
ERCC2 P18074 ERCC2 General transcription and DNA repair factor IIH helicase subunit XPD chr19 Census, Compendium Yes 231-246 16 2.78e-03 0.0 15 8.67 173 BLCA LUAD, BLCA, SKCM, STAD, HNSC
ARID5A Q03989 ARID5A AT-rich interactive domain-containing protein 5A chr2 Not Cancer Driver No 393-400 8 2.79e-03 100.0 6 9.38 64 COAD SKCM, CESC, COAD, LUSC, KIRC
RALB P11234 RALB Ras-related protein Ral-B chr2 Not Cancer Driver No 18-24 7 2.79e-03 0.0 11 29.73 37 - BRCA, BLCA, UCEC, STAD, LUSC, COAD, LUAD, KIRC
TMX1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 chr14 Not Cancer Driver No 17-22 6 2.79e-03 100.0 10 29.41 34 GBM BRCA, OV, COAD, GBM, UCEC
ABCA9 Q8IUA7 ABCA9 ATP-binding cassette sub-family A member 9 chr17 Not Cancer Driver No 1387-1397 11 2.80e-03 0.0 12 4.41 272 LUSC, UCEC SKCM, LUSC, STAD, COAD, BRCA, UCEC
OR6K3_ENST00000368146 Q8NGY3 OR6K3 Olfactory receptor 6K3 chr1 Not Cancer Driver No 271-276 6 2.81e-03 0.0 13 9.35 139 STAD SKCM, UCEC, READ, COAD, STAD, LUSC, BLCA
UMOD_ENST00000302509 P07911 UMOD Uromodulin chr16 Not Cancer Driver No 449-459 11 2.81e-03 16.67 14 11.11 126 - OV, LUAD, UCEC, READ, LUSC, THCA, STAD, SKCM
LILRB2_ENST00000314446 Q8N423 LILRB2 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 Not Cancer Driver No 127-183 57 2.81e-03 100.0 28 18.92 148 SKCM, LUAD HNSC, BLCA, STAD, SKCM, LUAD, LUSC, KIRC, CESC, UCEC, READ, COAD
SMAD4_ENST00000398417 Q13485 SMAD4 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 531-544 14 2.81e-03 21.43 18 9.09 198 READ LUSC, COAD, COT, GBM, PAAD, HNSC, KIRC, READ, SARC
RUFY4_ENST00000344321 Q6ZNE9 RUFY4 RUN and FYVE domain-containing protein 4 chr2 Not Cancer Driver No 492-534 43 2.81e-03 13.95 21 27.27 77 SKCM KIRC, HNSC, LUAD, BRCA, STAD, UCEC, LGG, OV, SKCM
CREB3L4_ENST00000271889 Q8TEY5 CREB3L4 Cyclic AMP-responsive element-binding protein 3-like protein 4 chr1 Not Cancer Driver No 151-197 47 2.82e-03 72.34 16 29.09 55 - LUSC, BRCA, SKCM, BLCA, GBM, COAD, PRAD, UCEC, CESC
UGT3A2 Q3SY77 UGT3A2 UDP-glucuronosyltransferase 3A2 chr5 Not Cancer Driver No 462-474 13 2.82e-03 0.0 15 8.88 169 - OV, LUSC, COAD, BRCA, LUAD, LGG, SKCM, BLCA, READ, GBM
SLC12A5 Q9H2X9 SLC12A5 Solute carrier family 12 member 5 chr20 Not Cancer Driver No 328-335 8 2.83e-03 0.0 12 4.53 265 SKCM THCA, LUAD, OV, SKCM
CAPN13 Q6MZZ7 CAPN13 Calpain-13 chr2 Not Cancer Driver No 415-428 14 2.84e-03 100.0 16 10.26 156 SKCM OV, LUSC, SKCM, BRCA, LUAD, STAD
SLC34A2 O95436 SLC34A2 Sodium-dependent phosphate transport protein 2B chr4 Census Yes 621-634 14 2.84e-03 100.0 5 3.76 133 BRCA OV, THCA, BRCA, COAD, STAD
CFAP47 Q6ZTR5 CFAP47 Cilia- and flagella-associated protein 47 chrX Not Cancer Driver No 1576-1626 51 2.85e-03 100.0 22 4.99 441 - GBM, LUAD, PRAD, SKCM, HNSC, COAD, LUSC, UCEC, OAD, LIHC
DBNDD2_ENST00000372720 Q9BQY9 DBNDD2 Dysbindin domain-containing protein 2 chr20 Not Cancer Driver No 98-122 25 2.87e-03 24.0 16 53.33 30 - UCEC, STAD, SKCM, LUSC, LUAD, COAD, BLCA
HSPA1A P0DMV8 HSPA1A Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 588-639 52 2.87e-03 63.46 13 54.17 24 STAD LUSC, OV, STAD, LUAD, PRAD, PAAD, BLCA, UCEC
APOBEC3H_ENST00000613677 Q6NTF7 APOBEC3H DNA dC->dU-editing enzyme APOBEC-3H chr22 Not Cancer Driver No 170-176 7 2.87e-03 0.0 10 21.74 46 BLCA BRCA, UCEC, BLCA
PCDHA11 Q9Y5I1 PCDHA11 Protocadherin alpha-11 chr5 Not Cancer Driver No 742-743 2 2.89e-03 100.0 11 3.59 306 READ STAD, SKCM, UCEC, COAD, READ, BLCA
PCDHA12 Q9UN75 PCDHA12 Protocadherin alpha-12 chr5 Not Cancer Driver No 537-540 4 2.89e-03 0.0 13 3.95 329 SKCM UCEC, LUAD, STAD, SKCM, BLCA, COAD, LGG, PRAD
NLRP12_ENST00000324134 P59046 NLRP12 NACHT, LRR and PYD domains-containing protein 12 chr19 Not Cancer Driver No 141-146 6 2.89e-03 100.0 13 4.17 312 GBM PRAD, UCEC, GBM, LUSC, CESC, STAD, LGG
KRT8_ENST00000546897 P05787 KRT8 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 31-31 1 2.90e-03 100.0 8 11.76 68 LIHC, UCEC, KIRC LIHC, LUAD, UCEC, KIRC
MGA Q8IWI9 MGA MAX gene-associated protein chr15 Compendium Yes 2433-2439 7 2.91e-03 100.0 12 3.51 342 UCEC OV, COAD, HNSC, UCEC, LUSC, READ, PAAD
RIPOR3_ENST00000045083 Q96MK2 RIPOR3 RIPOR family member 3 chr20 Not Cancer Driver No 302-353 52 2.91e-03 69.23 21 15.67 134 SKCM SKCM, UCEC, LUSC, LGG, OV, CESC, SARC, BLCA, GBM, LIHC, BRCA, LUAD, HNSC
SOGA1 O94964-2 SOGA1 Isoform 2 of Protein SOGA1 chr20 Not Cancer Driver No 702-741 40 2.91e-03 100.0 17 8.85 192 - LUAD, PRAD, BRCA, READ, HNSC, KIRC, LUSC, STAD, COAD, LAML
ABCB1_ENST00000265724 P08183 ABCB1 ATP-dependent translocase ABCB1 chr7 Compendium Yes 467-472 6 2.92e-03 0.0 13 3.53 368 SKCM, UCEC PRAD, SKCM, STAD, UCEC
ABCB1_ENST00000265724 P08183 ABCB1 ATP-dependent translocase ABCB1 chr7 Compendium Yes 958-963 6 2.92e-03 0.0 11 2.99 368 GBM HNSC, LIHC, KIRC, SKCM, GBM, STAD
TAF1_ENST00000373790 P21675 TAF1 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 1219-1226 8 2.92e-03 100.0 14 3.68 380 STAD UCEC, STAD, BRCA, LGG, LUAD, CESC, HNSC
INMT O95050 INMT Indolethylamine N-methyltransferase chr7 Not Cancer Driver No 212-212 1 2.92e-03 0.0 9 13.04 69 SKCM SKCM
MAN1B1 Q9UKM7 MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase chr9 Not Cancer Driver No 153-155 3 2.92e-03 100.0 9 12.16 74 GBM SKCM, LAML, GBM, STAD, LUSC
PROC P04070 PROC Vitamin K-dependent protein C chr2 Not Cancer Driver No 300-303 4 2.92e-03 0.0 9 12.0 75 UCEC, COAD UCEC, COAD, STAD, HNSC, SKCM, THCA
ZNF490 Q9ULM2 ZNF490 Zinc finger protein 490 chr19 Not Cancer Driver No 232-236 5 2.92e-03 0.0 9 10.98 82 SKCM SKCM, STAD, CESC, UCEC, BRCA
OR2L13_ENST00000358120 Q8N349 OR2L13 Olfactory receptor 2L13 chr1 Not Cancer Driver No 260-265 6 2.92e-03 0.0 14 8.38 167 LUSC LUSC, READ, SKCM, LUAD, BRCA, BLCA, OV
ATP10A O60312 ATP10A Phospholipid-transporting ATPase VA chr15 Not Cancer Driver No 208-214 7 2.93e-03 14.29 12 3.23 372 COAD GBM, LUAD, STAD, COAD, HNSC, READ, BLCA
SMARCA4 P51532 SMARCA4 Transcription activator BRG1 chr19 Census, Compendium Yes 882-885 4 2.93e-03 0.0 14 3.95 354 - KIRC, BRCA, SKCM, BLCA, LUAD, COAD, LGG
CYP26C1 Q6V0L0 CYP26C1 Cytochrome P450 26C1 chr10 Not Cancer Driver No 392-443 52 2.93e-03 32.69 13 40.62 32 - SKCM, OV, SARC, UCEC, CESC, HNSC, LUAD, STAD, COAD
TRIM65 Q6PJ69 TRIM65 Tripartite motif-containing protein 65 chr17 Not Cancer Driver No 383-418 36 2.93e-03 0.0 14 25.45 55 - LUAD, LUSC, STAD, KIRC, SKCM, HNSC, UCEC
TRIOBP_ENST00000644935 Q9H2D6 TRIOBP TRIO and F-actin-binding protein chr22 Not Cancer Driver No 702-710 9 2.93e-03 100.0 11 2.78 396 - GBM, CESC, SKCM, UCEC, THCA, LIHC, READ, BLCA
ZNF181 Q2M3W8 ZNF181 Zinc finger protein 181 chr19 Not Cancer Driver No 302-305 4 2.94e-03 0.0 8 10.53 76 LUSC, UCEC, GBM LUSC, STAD, UCEC, GBM, KIRC
TRIO O75962 TRIO Triple functional domain protein chr5 Not Cancer Driver No 1860-1870 11 2.94e-03 100.0 11 2.75 400 GBM LUAD, GBM, STAD, SKCM, UCEC
KRTAP5-1 Q6L8H4 KRTAP5-1 Keratin-associated protein 5-1 chr11 Not Cancer Driver No 183-193 11 2.95e-03 100.0 10 21.28 47 LUAD HNSC, SKCM, UCEC, LUAD, STAD, KIRC
COL21A1 Q96P44 COL21A1 Collagen alpha-1(XXI) chain chr6 Not Cancer Driver No 215-232 18 2.96e-03 22.22 21 7.05 298 SKCM SARC, OV, PRAD, SKCM, LUSC, LUAD
NOS1_ENST00000317775 P29475 NOS1 Nitric oxide synthase, brain chr12 Not Cancer Driver No 415-419 5 2.96e-03 0.0 14 3.45 406 GBM GBM, BRCA, STAD, SARC, SKCM, READ
CUL7_ENST00000265348 Q14999 CUL7 Cullin-7 chr6 Not Cancer Driver No 148-185 38 2.96e-03 2.63 15 7.94 189 STAD, OV HNSC, STAD, OV, SARC, KIRC, SKCM, LUSC
SPANXN5 Q5MJ07 SPANXN5 Sperm protein associated with the nucleus on the X chromosome N5 chrX Not Cancer Driver No 27-49 23 2.97e-03 91.3 20 74.07 27 SKCM HNSC, SKCM, PRAD, LUSC, LUAD
ZC3H6_ENST00000343936 P61129 ZC3H6 Zinc finger CCCH domain-containing protein 6 chr2 Not Cancer Driver No 216-229 14 2.97e-03 100.0 10 6.76 148 UCEC KIRC, SKCM, UCEC, OV, PRAD, LUSC
FAM47B Q8NA70 FAM47B Protein FAM47B chrX Not Cancer Driver No 524-536 13 2.97e-03 100.0 19 6.76 281 UCEC LUAD, OV, PRAD, SKCM, BLCA, HNSC, COAD, GBM, STAD, LUSC, UCEC
SPATA8 Q6RVD6 SPATA8 Spermatogenesis-associated protein 8 chr15 Not Cancer Driver No 17-43 27 2.97e-03 92.86 29 50.0 58 SKCM SKCM, LUSC, HNSC, KIRC, COAD, READ, LUAD, BLCA, UCEC
ARHGEF5 Q12774 ARHGEF5 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 4-28 25 2.98e-03 100.0 13 7.65 170 - COAD, LIHC, CESC, GBM, SKCM, BLCA, LUAD, UCEC, BRCA
NET1 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein chr10 Not Cancer Driver No 65-109 45 2.99e-03 100.0 15 25.0 60 - OV, BRCA, PRAD, LUAD, COAD, READ, UCEC, CESC, STAD
SETD2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 chr3 Census, Compendium Yes 1496-1541 46 3.00e-03 4.35 19 5.9 322 - LUAD, GBM, BRCA, BLCA, LUSC, STAD, UCEC, LIHC, KIRC, SKCM
UNC79_ENST00000393151 Q9P2D8 UNC79 Protein unc-79 homolog chr14 Not Cancer Driver No 765-773 9 3.01e-03 100.0 14 2.4 584 STAD, SKCM BLCA, STAD, READ, SKCM
ASXL3 Q9C0F0 ASXL3 Putative Polycomb group protein ASXL3 chr18 Not Cancer Driver No 1370-1375 6 3.01e-03 100.0 12 2.09 574 SKCM SKCM, COAD
CARD11 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 chr7 Census, Compendium Yes 415-433 19 3.02e-03 0.0 20 6.47 309 SKCM STAD, CESC, KIRC, SKCM, LUSC, READ, COAD, LUAD
GPKOW Q92917 GPKOW G-patch domain and KOW motifs-containing protein chrX Not Cancer Driver No 173-175 3 3.02e-03 33.33 8 10.0 80 GBM, LUAD GBM, CESC, LUAD, SKCM, BLCA
ACKR4 Q9NPB9 ACKR4 Atypical chemokine receptor 4 chr3 Not Cancer Driver No 184-190 7 3.02e-03 0.0 10 19.23 52 LUAD BRCA, LUAD, HNSC, COAD, LUSC, UCEC
VPS53 Q5VIR6 VPS53 Vacuolar protein sorting-associated protein 53 homolog chr17 Not Cancer Driver No 221-224 4 3.03e-03 50.0 9 10.84 83 SKCM, STAD SKCM, STAD, LUAD, READ, LUSC
ARHGAP35_ENST00000614079 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 chr19 Census, Compendium Yes 863-871 9 3.04e-03 0.0 7 2.73 256 UCEC UCEC, SARC, LUSC
GJA8 P48165 GJA8 Gap junction alpha-8 protein chr1 Not Cancer Driver No 67-126 60 3.04e-03 20.0 43 30.94 139 - KIRC, READ, CESC, OV, STAD, UCEC, LUAD, PRAD, BLCA, LUSC, SKCM, HNSC, COAD
RAC1_ENST00000348035 P63000 RAC1 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 159-159 1 3.04e-03 0.0 8 12.12 66 HNSC READ, UCEC, CESC, HNSC
ALG10B Q5I7T1 ALG10B Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 Not Cancer Driver No 210-258 49 3.05e-03 18.0 28 30.77 91 - LUAD, LUSC, READ, SKCM, THCA, KIRC, GBM, OV, HNSC, LIHC, STAD
ARID1A O14497 ARID1A AT-rich interactive domain-containing protein 1A chr1 Census, Compendium Yes 2233-2239 7 3.05e-03 0.0 6 2.18 275 UCEC, BLCA UCEC, READ, BLCA
MXRA5 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 chrX Not Cancer Driver No 2006-2010 5 3.05e-03 100.0 11 1.43 767 SKCM SKCM, LGG, LUAD
ANK2 Q01484 ANK2 Ankyrin-2 chr4 Not Cancer Driver No 3837-3844 8 3.05e-03 100.0 12 1.55 774 - GBM, HNSC, LUAD, SKCM, STAD, BLCA, COAD, OV, LUSC
ZNF749 O43361 ZNF749 Zinc finger protein 749 chr19 Not Cancer Driver No 457-457 1 3.06e-03 0.0 8 8.0 100 LUAD, PRAD LUAD, UCEC, PRAD
KMT2D O14686 KMT2D Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 5068-5114 47 3.06e-03 100.0 22 2.82 779 - LUAD, COAD, UCEC, DLBC, BLCA, KIRC, HNSC, SKCM, READ, PRAD, CESC
CDH2 P19022 CDH2 Cadherin-2 chr18 Not Cancer Driver No 421-437 17 3.08e-03 0.0 17 7.11 239 SKCM SKCM, LUSC, PAAD, HNSC, READ, PRAD, LUAD
PLXND1 Q9Y4D7 PLXND1 Plexin-D1 chr3 Not Cancer Driver No 1484-1487 4 3.08e-03 0.0 5 1.96 255 BRCA LIHC, CESC, HNSC, BRCA, COAD
C12orf43_ENST00000288757 Q96C57 CUSTOS Protein CUSTOS chr12 Not Cancer Driver No 25-32 8 3.10e-03 50.0 10 25.0 40 BLCA, CESC BLCA, CESC, READ
ZNF665 Q9H7R5 ZNF665 Zinc finger protein 665 chr19 Not Cancer Driver No 477-483 7 3.10e-03 28.57 14 6.33 221 BRCA, OV STAD, BLCA, SKCM, BRCA, OV, COT, COAD
POTEH Q6S545 POTEH POTE ankyrin domain family member H chr22 Not Cancer Driver No 456-465 10 3.10e-03 100.0 16 7.21 222 SKCM LIHC, LUAD, SKCM, STAD, LUSC, BRCA
RNF217 Q8TC41 RNF217 E3 ubiquitin-protein ligase RNF217 chr6 Not Cancer Driver No 502-538 37 3.11e-03 5.41 17 23.94 71 SKCM HNSC, SKCM, STAD, READ, LUAD, LIHC, UCEC
ERC2_ENST00000612797 O15083 ERC2 ERC protein 2 chr3 Not Cancer Driver No 17-31 15 3.11e-03 100.0 23 8.71 264 SKCM BRCA, GBM, HNSC, LIHC, SKCM, LUAD
PCLO Q9Y6V0 PCLO Protein piccolo chr7 Not Cancer Driver No 4133-4137 5 3.12e-03 100.0 11 0.68 1627 SKCM LUAD, SKCM, GBM
TRPC5 Q9UL62 TRPC5 Short transient receptor potential channel 5 chrX Not Cancer Driver No 156-171 16 3.12e-03 0.0 15 5.88 255 UCEC, SKCM READ, LUAD, BRCA, UCEC, SKCM, PRAD
SMURF2 Q9HAU4 SMURF2 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 427-431 5 3.12e-03 20.0 9 10.34 87 SKCM LUSC, SKCM
PCDHB11 Q9Y5F2 PCDHB11 Protocadherin beta-11 chr5 Not Cancer Driver No 529-537 9 3.13e-03 0.0 18 7.76 232 STAD STAD, BRCA, LUAD, HNSC, LUSC
FOXD2 O60548 FOXD2 Forkhead box protein D2 chr1 Not Cancer Driver No 133-186 54 3.15e-03 0.0 11 44.0 25 - STAD, COAD, HNSC, LUSC, PRAD, CESC, BLCA, LIHC, THCA
WNT9B O14905 WNT9B Protein Wnt-9b chr17 Not Cancer Driver No 168-189 22 3.15e-03 31.82 12 25.53 47 STAD, SKCM THCA, STAD, KIRC, READ, SKCM
FAM47A Q5JRC9 FAM47A Protein FAM47A chrX Not Cancer Driver No 498-508 11 3.16e-03 100.0 18 4.79 376 - OV, LUSC, UCEC, KIRC, STAD, BRCA, COAD, LUAD, BLCA, READ, GBM
INSL3_ENST00000317306 P51460 INSL3 Insulin-like 3 chr19 Not Cancer Driver No 60-60 1 3.16e-03 100.0 14 56.0 25 READ, COAD READ, COAD
SYCE1L A8MT33 SYCE1L Synaptonemal complex central element protein 1-like chr16 Not Cancer Driver No 210-210 1 3.16e-03 100.0 14 53.85 26 COAD, READ COAD, READ
CCDC141_ENST00000443758 Q6ZP82-2 CCDC141 Isoform 2 of Coiled-coil domain-containing protein 141 chr2 Not Cancer Driver No 1274-1319 46 3.16e-03 100.0 23 7.3 315 SKCM LUAD, SKCM, READ, OV, COAD, HNSC, BRCA, PRAD, UCEC, KIRC, LUSC, LIHC, GBM
FOXK1 P85037 FOXK1 Forkhead box protein K1 chr7 Not Cancer Driver No 337-341 5 3.16e-03 0.0 8 8.16 98 GBM LIHC, GBM
RGR P47804 RGR RPE-retinal G protein-coupled receptor chr10 Not Cancer Driver No 219-230 12 3.16e-03 0.0 10 23.81 42 - UCEC, LUSC, BLCA, GBM, SKCM, HNSC
SYT6_ENST00000610222 Q5T7P8 SYT6 Synaptotagmin-6 chr1 Not Cancer Driver No 249-249 1 3.16e-03 0.0 8 8.16 98 UCEC, HNSC UCEC, READ, HNSC, COAD, LUSC
ZNF844 Q08AG5 ZNF844 Zinc finger protein 844 chr19 Not Cancer Driver No 447-447 1 3.17e-03 100.0 9 7.83 115 GBM, LUAD GBM, LUAD, LGG, PRAD, SKCM
UNC80 Q8N2C7 UNC80 Protein unc-80 homolog chr2 Not Cancer Driver No 117-153 37 3.17e-03 100.0 15 5.14 292 LUAD STAD, LUAD, BLCA, BRCA, KIRC, LUSC
UNC80 Q8N2C7 UNC80 Protein unc-80 homolog chr2 Not Cancer Driver No 169-210 42 3.17e-03 100.0 17 5.82 292 LUAD OV, STAD, SARC, COAD, LUAD, LUSC, UCEC
TOX2_ENST00000358131 Q96NM4 TOX2 TOX high mobility group box family member 2 chr20 Not Cancer Driver No 370-377 8 3.18e-03 100.0 6 4.58 131 SKCM, READ COAD, SKCM, BLCA, READ
FGFR2_ENST00000358487 P21802 FGFR2 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 375-382 8 3.18e-03 0.0 13 5.46 238 UCEC LUSC, CESC, STAD, UCEC
PCDHB10 Q9UN67 PCDHB10 Protocadherin beta-10 chr5 Not Cancer Driver No 677-686 10 3.19e-03 100.0 2 0.82 244 READ, REO THCA, READ, SKCM, REO
FGD5 Q6ZNL6 FGD5 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 394-409 16 3.20e-03 100.0 15 5.42 277 - LGG, LIHC, BLCA, GBM, LUSC, COAD, BRCA, SKCM, LUAD
BPIFB3 P59826 BPIFB3 BPI fold-containing family B member 3 chr20 Not Cancer Driver No 88-90 3 3.20e-03 100.0 8 8.99 89 STAD READ, KIRC, UCEC, BRCA, STAD, SKCM, LUAD
ZNF878 C9JN71 ZNF878 Zinc finger protein 878 chr19 Not Cancer Driver No 153-188 36 3.22e-03 22.22 17 17.71 96 - STAD, KIRC, LGG, COAD, PRAD, READ, BRCA, SKCM, CESC, LUAD
DCLK2_ENST00000296550 Q8N568 DCLK2 Serine/threonine-protein kinase DCLK2 chr4 Not Cancer Driver No 275-276 2 3.22e-03 100.0 9 8.57 105 UCEC, SKCM STAD, UCEC, SKCM
CCDC141_ENST00000443758 Q6ZP82-2 CCDC141 Isoform 2 of Coiled-coil domain-containing protein 141 chr2 Not Cancer Driver No 649-664 16 3.26e-03 100.0 15 4.76 315 SKCM COAD, SKCM, LUAD, LUSC
KATNB1 Q9BVA0 KATNB1 Katanin p80 WD40 repeat-containing subunit B1 chr16 Not Cancer Driver No 361-422 62 3.26e-03 73.44 20 27.03 74 - PAAD, UCEC, BLCA, SKCM, LAML, LUSC, COAD, LUAD, READ, STAD
USH1C_ENST00000318024 Q9Y6N9 USH1C Harmonin chr11 Not Cancer Driver No 174-220 47 3.27e-03 41.67 21 17.36 121 SKCM SKCM, LIHC, HNSC, COAD, BLCA, LUSC, STAD, OV, UCEC, BRCA
PRKCI P41743 PRKCI Protein kinase C iota type chr3 Not Cancer Driver No 480-482 3 3.28e-03 0.0 10 9.09 110 READ, STAD SKCM, READ, COAD, STAD, LUSC, OV
NLRP6 P59044 NLRP6 NACHT, LRR and PYD domains-containing protein 6 chr11 Not Cancer Driver No 163-163 1 3.29e-03 100.0 16 13.79 116 READ, COAD READ, COAD
GRIN3A Q8TCU5 GRIN3A Glutamate receptor ionotropic, NMDA 3A chr9 Not Cancer Driver No 336-346 11 3.29e-03 18.18 13 4.14 314 SKCM LUAD, SKCM, UCEC, STAD, LUSC, SARC, CESC, KIRC
PCDHA8 Q9Y5H6 PCDHA8 Protocadherin alpha-8 chr5 Not Cancer Driver No 537-544 8 3.29e-03 0.0 15 4.24 354 - BRCA, STAD, SKCM, UCEC, HNSC, READ, LUAD, LUSC
EPS8L1 Q8TE68 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 Not Cancer Driver No 669-669 1 3.30e-03 0.0 20 15.87 126 COAD, BLCA, READ COAD, BLCA, READ
PCDHA1 Q9Y5I3 PCDHA1 Protocadherin alpha-1 chr5 Not Cancer Driver No 497-508 12 3.30e-03 0.0 16 4.72 339 STAD UCEC, SKCM, READ, HNSC, STAD, LUAD, LUSC, BRCA
KRTAP10-11 P60412 KRTAP10-11 Keratin-associated protein 10-11 chr21 Not Cancer Driver No 3-42 40 3.31e-03 100.0 22 31.88 69 GBM STAD, LUSC, KIRC, COAD, CESC, OV, SKCM, UCEC, BLCA, GBM, LUAD
TCF7L2_ENST00000355995 Q9NQB0 TCF7L2 Transcription factor 7-like 2 chr10 Census, Compendium Yes 418-420 3 3.31e-03 33.33 8 6.56 122 COAD, STAD COAD, READ, BRCA, LIHC, SARC, STAD
MYLK Q15746 MYLK Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1096-1106 11 3.32e-03 18.18 13 3.76 346 UCEC PRAD, KIRC, BLCA, UCEC, LIHC
SCN7A_ENST00000409855 Q01118 SCN7A Sodium channel protein type 7 subunit alpha chr2 Not Cancer Driver No 1352-1364 13 3.33e-03 84.62 15 3.78 397 GBM GBM, COAD, LUAD, LGG, BRCA, SKCM, CESC, HNSC
BRAT1 Q6PJG6 BRAT1 BRCA1-associated ATM activator 1 chr7 Not Cancer Driver No 644-644 1 3.34e-03 0.0 16 13.22 121 COAD, READ BRCA, COAD, READ
RFX1 P22670 RFX1 MHC class II regulatory factor RFX1 chr19 Not Cancer Driver No 369-370 2 3.34e-03 100.0 17 13.71 124 READ SKCM, READ, REO, COAD
RGPD4 Q7Z3J3 RGPD4 RanBP2-like and GRIP domain-containing protein 4 chr2 Not Cancer Driver No 1039-1049 11 3.35e-03 100.0 14 3.64 385 SKCM LUAD, LUSC, CESC, SKCM, UCEC
PKD1 P98161 PKD1 Polycystin-1 chr16 Not Cancer Driver No 922-956 35 3.36e-03 100.0 16 4.0 400 - BRCA, STAD, HNSC, SKCM, BLCA, LAML, UCEC, LUAD, COAD
MAP1S Q66K74 MAP1S Microtubule-associated protein 1S chr19 Not Cancer Driver No 440-440 1 3.36e-03 0.0 18 13.33 135 COAD OAD, READ, COAD
MUC6 Q6W4X9 MUC6 Mucin-6 chr11 Not Cancer Driver No 1984-1998 15 3.37e-03 100.0 14 3.42 409 BLCA SKCM, BLCA, LUSC, LUAD
DCHS1 Q96JQ0 DCHS1 Protocadherin-16 chr11 Not Cancer Driver No 96-114 19 3.39e-03 100.0 13 2.9 448 - BRCA, OV, PRAD, UCEC, LIHC, SKCM, CESC, STAD, LUAD, COAD
KMT2A_ENST00000389506 Q03164 KMT2A Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 2062-2088 27 3.39e-03 100.0 14 3.14 446 - SARC, COAD, UCEC, OV, SKCM, HNSC, CESC, BRCA, STAD, PRAD
USF1 P22415 USF1 Upstream stimulatory factor 1 chr1 Not Cancer Driver No 284-291 8 3.40e-03 0.0 11 21.15 52 GBM BRCA, GBM
DYNC2H1_ENST00000375735 Q8NCM8 DYNC2H1 Cytoplasmic dynein 2 heavy chain 1 chr11 Not Cancer Driver No 3615-3654 40 3.42e-03 100.0 17 3.33 511 - STAD, KIRC, BRCA, SKCM, UCEC, LUSC, LIHC, COAD, CESC, LUAD
IGFBPL1 Q8WX77 IGFBPL1 Insulin-like growth factor-binding protein-like 1 chr9 Not Cancer Driver No 223-252 30 3.42e-03 0.0 12 38.71 31 SKCM LUSC, BLCA, LIHC, BRCA, STAD, SKCM, LUAD
KLHL35 Q6PF15 KLHL35 Kelch-like protein 35 chr11 Not Cancer Driver No 297-348 52 3.42e-03 3.85 12 44.44 27 LUAD LUSC, KIRC, STAD, BLCA, COAD, LUAD, LIHC, READ
SRCAP Q6ZRS2 SRCAP Helicase SRCAP chr16 Not Cancer Driver No 2364-2428 65 3.42e-03 100.0 23 5.25 438 - SARC, LAML, READ, LUAD, LUSC, STAD, COAD, SKCM, UCEC, CESC, BRCA, GBM
CRB1 P82279 CRB1 Protein crumbs homolog 1 chr1 Not Cancer Driver No 590-602 13 3.43e-03 30.77 16 3.45 464 SKCM, LUAD COAD, SKCM, KIRC, LUAD, BLCA, LUSC, OV
LRIG1 Q96JA1 LRIG1 Leucine-rich repeats and immunoglobulin-like domains protein 1 chr3 Not Cancer Driver No 24-26 3 3.43e-03 100.0 16 9.52 168 READ, COAD READ, COAD
FAM47C Q5HY64 FAM47C Putative protein FAM47C chrX Census Yes 221-226 6 3.43e-03 100.0 14 3.02 463 - SKCM, STAD, LUAD, COAD, PRAD, KIRC, BLCA, LUSC, LGG, HNSC
FAT3_ENST00000409404 Q8TDW7 FAT3 Protocadherin Fat 3 chr11 Census, Compendium Yes 252-269 18 3.44e-03 100.0 18 1.49 1207 COAD STAD, PRAD, CESC, LUSC, KIRC, READ, LUAD, COAD, SKCM
PBRM1_ENST00000296302 Q86U86 PBRM1 Protein polybromo-1 chr3 Census, Compendium Yes 556-614 59 3.44e-03 0.0 23 10.9 211 KIRC HNSC, LGG, SKCM, KIRC, STAD, BLCA, BRCA, COAD, CESC
FBLN2_ENST00000295760 P98095 FBLN2 Fibulin-2 chr3 Census Yes 1105-1109 5 3.44e-03 0.0 9 5.92 152 GBM, STAD PAAD, GBM, STAD, READ, UCEC
PRKDC P78527 PRKDC DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 2702-2736 35 3.46e-03 100.0 16 2.97 538 - COAD, LIHC, HNSC, LGG, BLCA, PRAD, OV, LUAD, STAD, SARC, SKCM
AGAP5 A6NIR3 AGAP5 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 chr10 Not Cancer Driver No 127-137 11 3.46e-03 100.0 13 22.03 59 STAD LAML, BRCA, STAD, KIRC, UCEC
MROH2B Q7Z745 MROH2B Maestro heat-like repeat-containing protein family member 2B chr5 Not Cancer Driver No 223-231 9 3.46e-03 0.0 14 2.54 552 SKCM HNSC, STAD, SKCM, LUAD, LUSC, GBM
PCMT1_ENST00000464889 A0A0A0MRJ6 PCMT1 Protein-L-isoaspartate O-methyltransferase chr6 Not Cancer Driver No 119-168 50 3.47e-03 100.0 16 44.44 36 LUAD LUAD, BRCA, OV, LIHC, HNSC, LGG, COAD, BLCA
SCN9A_ENST00000642356 Q15858 SCN9A Sodium channel protein type 9 subunit alpha chr2 Not Cancer Driver No 599-604 6 3.47e-03 100.0 1 0.22 462 GBM GBM, STAD
MROH2B Q7Z745 MROH2B Maestro heat-like repeat-containing protein family member 2B chr5 Not Cancer Driver No 1102-1112 11 3.48e-03 0.0 15 2.72 552 BLCA BLCA, HNSC, CESC, STAD, LUAD, UCEC, GBM, LUSC
TP63 Q9H3D4 TP63 Tumor protein 63 chr3 Census, Compendium Yes 184-194 11 3.49e-03 0.0 12 5.24 229 BLCA HNSC, GBM, STAD, CESC, UCEC, BLCA, READ, LUSC
MORC3 Q14149 MORC3 MORC family CW-type zinc finger protein 3 chr21 Not Cancer Driver No 521-576 56 3.49e-03 100.0 19 16.52 115 - LUAD, CESC, GBM, UCEC, HNSC, OV, SKCM, BRCA, BLCA
CNTNAP2 Q9UHC6 CNTNAP2 Contactin-associated protein-like 2 chr7 Census Yes 359-367 9 3.49e-03 33.33 17 2.97 573 SKCM LIHC, OV, LUAD, SKCM, BLCA
LRRC37A3 O60309 LRRC37A3 Leucine-rich repeat-containing protein 37A3 chr17 Not Cancer Driver No 369-374 6 3.50e-03 100.0 11 6.51 169 BRCA, BLCA BRCA, LAML, SKCM, SARC, BLCA
DIPK2A Q8NDZ4 DIPK2A Divergent protein kinase domain 2A chr3 Not Cancer Driver No 222-233 12 3.51e-03 0.0 10 17.86 56 LUAD, LIHC LUAD, SKCM, OV, UCEC, LIHC
HCN4 Q9Y3Q4 HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 Not Cancer Driver No 237-239 3 3.51e-03 0.0 8 4.23 189 GBM GBM
EYA4_ENST00000367895 O95677 EYA4 Eyes absent homolog 4 chr6 Not Cancer Driver No 152-152 1 3.52e-03 100.0 11 5.98 184 UCEC, COAD, STAD UCEC, COAD, STAD, LUAD
CACNA1E_ENST00000621551 Q15878 CACNA1E Voltage-dependent R-type calcium channel subunit alpha-1E chr1 Not Cancer Driver No 919-926 8 3.53e-03 100.0 15 1.93 779 - CESC, STAD, LUSC, BRCA, SKCM, PRAD, BLCA, COAD
EFNB3 Q15768 EFNB3 Ephrin-B3 chr17 Not Cancer Driver No 52-91 40 3.53e-03 0.0 15 33.33 45 SKCM LGG, READ, UCEC, CESC, SKCM, COAD, SARC, HNSC
HYDIN Q4G0P3 HYDIN Hydrocephalus-inducing protein homolog chr16 Not Cancer Driver No 664-678 15 3.54e-03 100.0 13 1.48 881 SKCM LUAD, COAD, SKCM, PAAD, STAD, LUSC
TOP2A P11388 TOP2A DNA topoisomerase 2-alpha chr17 Compendium Yes 212-215 4 3.54e-03 0.0 7 4.67 150 OV OV
KRTAP4-6 Q9BYQ5 KRTAP4-6 Keratin-associated protein 4-6 chr17 Not Cancer Driver No 37-47 11 3.55e-03 100.0 17 19.1 89 LUAD KIRC, LUAD, HNSC, SKCM, PRAD, OV, BRCA, BLCA, UCEC
MROH5 Q6ZUA9 MROH5 Maestro heat-like repeat family member 5 chr8 Not Cancer Driver No 469-472 4 3.55e-03 0.0 8 4.17 192 STAD, SKCM, OV STAD, READ, LUSC, SKCM, OV
MXRA5 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 chrX Not Cancer Driver No 2145-2159 15 3.56e-03 100.0 17 2.22 767 LUAD LUAD, COAD, KIRC, STAD, READ, GBM, SKCM, LAML
PCARE A6NGG8 PCARE Photoreceptor cilium actin regulator chr2 Not Cancer Driver No 1159-1161 3 3.57e-03 100.0 9 4.09 220 BLCA LUSC, BLCA, COAD, LUAD, SKCM, BRCA
NCOR2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 507-514 8 3.57e-03 100.0 4 1.04 384 COAD STAD, OV, COAD
BTC P35070 BTC Probetacellulin chr4 Not Cancer Driver No 144-174 31 3.58e-03 32.26 14 45.16 31 SKCM HNSC, LGG, BLCA, COAD, SKCM, LUAD
PTPN7_ENST00000367279 P35236-2 PTPN7 Isoform 2 of Tyrosine-protein phosphatase non-receptor type 7 chr1 Not Cancer Driver No 283-336 54 3.58e-03 100.0 21 36.84 57 - STAD, LUSC, HNSC, SKCM, OV, LUAD, COAD, UCEC, BRCA
PARP4 Q9UKK3 PARP4 Protein mono-ADP-ribosyltransferase PARP4 chr13 Compendium Yes 1039-1043 5 3.59e-03 0.0 8 3.54 226 BLCA LIHC, CESC, SKCM, KIRC, BLCA, PRAD, OV
ZFHX4_ENST00000518282 Q86UP3 ZFHX4 Zinc finger homeobox protein 4 chr8 Not Cancer Driver No 2611-2617 7 3.59e-03 100.0 14 1.08 1297 - UCEC, SKCM, LIHC, HNSC, BRCA, STAD, PAAD, READ
PLOD3 O60568 PLOD3 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 Not Cancer Driver No 256-297 42 3.60e-03 9.52 20 18.52 108 SKCM BRCA, OV, BLCA, SKCM, KIRC, UCEC, GBM, LUSC, LUAD
SSUH2 Q9Y2M2 SSUH2 Protein SSUH2 homolog chr3 Not Cancer Driver No 189-198 10 3.61e-03 100.0 10 16.95 59 - PAAD, LUSC, LUAD, UCEC, LIHC, HNSC, SARC, BRCA
MUC3A Q02505 MUC3A Mucin-3A chr7 Not Cancer Driver No 2967-2974 8 3.61e-03 100.0 9 4.05 222 LUAD, SKCM LUAD, SKCM, BLCA, UCEC, STAD
SNRPD3 P62318 SNRPD3 Small nuclear ribonucleoprotein Sm D3 chr22 Not Cancer Driver No 94-96 3 3.62e-03 100.0 7 35.0 20 LUAD STAD, CESC, UCEC, LUAD
ADGRL4 Q9HBW9 ADGRL4 Adhesion G protein-coupled receptor L4 chr1 Not Cancer Driver No 598-598 1 3.62e-03 0.0 9 3.64 247 CESC, SKCM GBM, UCEC, CESC, BLCA, SKCM
MYO18A Q92614 MYO18A Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1645-1648 4 3.64e-03 100.0 11 4.07 270 COAD, LIHC SKCM, COAD, UCEC, CESC, LIHC
TUBB1 Q9H4B7 TUBB1 Tubulin beta-1 chain chr20 Not Cancer Driver No 297-318 22 3.64e-03 0.0 15 20.55 73 LUAD LUAD, UCEC, SKCM, STAD, LUSC, HNSC, COAD, GBM
FGD5 Q6ZNL6 FGD5 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 472-474 3 3.64e-03 100.0 8 2.89 277 LUAD LUAD, SKCM, LUSC, GBM, LGG, UCEC
IL9R Q01113 IL9R Interleukin-9 receptor chrX Not Cancer Driver No 432-440 9 3.64e-03 100.0 6 6.25 96 - LUAD, UCEC, GBM, BRCA, OV, READ, KIRC, COAD
DNAH5 Q8TE73 DNAH5 Dynein axonemal heavy chain 5 chr5 Not Cancer Driver No 3548-3560 13 3.66e-03 100.0 19 1.31 1446 SKCM BLCA, HNSC, SKCM, UCEC, LUSC, COAD
PCDHGA1 Q9Y5H4 PCDHGA1 Protocadherin gamma-A1 chr5 Not Cancer Driver No 696-696 1 3.66e-03 0.0 8 2.82 284 UCEC, READ UCEC, COAD, GBM, READ, STAD
CAMTA1 Q9Y6Y1 CAMTA1 Calmodulin-binding transcription activator 1 chr1 Census, Compendium Yes 809-811 3 3.67e-03 100.0 8 2.65 302 UCEC, SKCM, LUAD STAD, HNSC, UCEC, SKCM, LUAD
SPANXN1 Q5VSR9 SPANXN1 Sperm protein associated with the nucleus on the X chromosome N1 chrX Not Cancer Driver No 32-38 7 3.68e-03 100.0 12 41.38 29 LUSC PRAD, STAD, LUSC, KIRC, SKCM, LUAD
CPAMD8 Q8IZJ3 CPAMD8 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 chr19 Not Cancer Driver No 568-570 3 3.71e-03 0.0 11 3.07 358 SKCM STAD, LUSC, SKCM
TAF1_ENST00000373790 P21675 TAF1 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 843-843 1 3.71e-03 0.0 8 2.11 380 UCEC UCEC
KLK8_ENST00000600767 O60259 KLK8 Kallikrein-8 chr19 Not Cancer Driver No 239-247 9 3.74e-03 0.0 13 20.0 65 STAD OV, PRAD, SKCM, STAD, SARC, LGG, BRCA, UCEC, LUAD
PCNT O95613 PCNT Pericentrin chr21 Not Cancer Driver No 841-843 3 3.74e-03 100.0 9 1.96 460 LUSC, BLCA, LIHC LUSC, BLCA, HNSC, LUAD, LIHC
CALN1 Q9BXU9 CALN1 Calcium-binding protein 8 chr7 Not Cancer Driver No 125-137 13 3.75e-03 0.0 16 17.02 94 SKCM, GBM SKCM, COAD, LUAD, STAD, OV, GBM
KRT27 Q7Z3Y8 KRT27 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 172-195 24 3.75e-03 0.0 15 18.29 82 SKCM COAD, BRCA, LIHC, LUSC, STAD, PRAD, SKCM, UCEC, LUAD
MUC5B Q9HC84 MUC5B Mucin-5B chr11 Not Cancer Driver No 2024-2080 57 3.76e-03 100.0 25 2.64 946 - BLCA, COAD, SKCM, CESC, OV, LUSC, KIRC, UCEC, BRCA, LUAD, STAD
EGFR P00533 EGFR Epidermal growth factor receptor chr7 Census, Compendium Yes 62-62 1 3.77e-03 0.0 8 1.79 446 LUAD, GBM, LGG LUAD, GBM, LGG
HSPG2 P98160 HSPG2 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 Compendium Yes 1260-1260 1 3.78e-03 100.0 8 1.54 518 BLCA BLCA
PRSS38 A1L453 PRSS38 Serine protease 38 chr1 Not Cancer Driver No 72-84 13 3.78e-03 0.0 6 7.89 76 LUAD, GBM UCEC, SKCM, LUAD, PRAD, GBM
KRTAP4-3 Q9BYR4 KRTAP4-3 Keratin-associated protein 4-3 chr17 Not Cancer Driver No 63-71 9 3.79e-03 0.0 4 6.06 66 READ, COAD PAAD, READ, UCEC, GBM, COAD
URI1 O94763 URI1 Unconventional prefoldin RPB5 interactor 1 chr19 Not Cancer Driver No 309-317 9 3.79e-03 100.0 5 5.68 88 UCEC READ, STAD, LUSC, UCEC, COAD
SOD3 P08294 SOD3 Extracellular superoxide dismutase [Cu-Zn] chr4 Not Cancer Driver No 54-58 5 3.81e-03 66.67 13 44.83 29 COAD, READ PRAD, COAD, READ
DTX2 Q86UW9 DTX2 Probable E3 ubiquitin-protein ligase DTX2 chr7 Not Cancer Driver No 334-365 32 3.82e-03 100.0 16 19.05 84 - LUSC, OV, LUAD, LAML, GBM, COAD, STAD, BLCA, BRCA
OR10V1 Q8NGI7 OR10V1 Olfactory receptor 10V1 chr11 Not Cancer Driver No 88-101 14 3.83e-03 0.0 14 20.29 69 SKCM, LUAD, GBM STAD, SKCM, LUAD, KIRC, BRCA, GBM
XIRP2_ENST00000628543 A4UGR9 XIRP2 Xin actin-binding repeat-containing protein 2 chr2 Not Cancer Driver No 562-562 1 3.84e-03 100.0 10 0.9 1112 SKCM, READ SKCM, KIRC, STAD, READ
IQSEC3 Q9UPP2 IQSEC3 IQ motif and SEC7 domain-containing protein 3 chr12 Not Cancer Driver No 929-975 47 3.84e-03 6.38 18 10.53 171 - LUAD, STAD, BLCA, SKCM, LUSC, CESC, LIHC, GBM, COAD, HNSC
MYH7 P12883 MYH7 Myosin-7 chr14 Not Cancer Driver No 1325-1382 58 3.85e-03 100.0 30 6.44 466 - BLCA, HNSC, OV, PRAD, BRCA, STAD, UCEC, SKCM, LUAD, GBM, READ, LUSC
OBSCN_ENST00000422127 Q5VST9 OBSCN Obscurin chr1 Not Cancer Driver No 998-998 1 3.85e-03 100.0 8 0.64 1252 BLCA BLCA, BRCA
PSMB5 P28074 PSMB5 Proteasome subunit beta type-5 chr14 Not Cancer Driver No 5-32 28 3.88e-03 100.0 14 35.9 39 OV OV, LUAD, DLBC, LIHC, BRCA, KIRC
PGA3 P0DJD8 PGA3 Pepsin A-3 chr11 Not Cancer Driver No 20-67 48 3.89e-03 20.83 13 68.42 19 SKCM LUSC, LUAD, STAD, HNSC, BLCA, BRCA, SKCM
OR2B11 Q5JQS5 OR2B11 Olfactory receptor 2B11 chr1 Not Cancer Driver No 162-175 14 3.89e-03 0.0 25 21.74 115 - LUSC, LUAD, READ, LGG, BRCA, STAD, COAD, UCEC, GBM, BLCA
GOLGA6L2 Q8N9W4 GOLGA6L2 Golgin subfamily A member 6-like protein 2 chr15 Not Cancer Driver No 598-601 4 3.91e-03 100.0 1 1.72 58 UCEC, BRCA UCEC, BRCA
SMARCC2_ENST00000267064 Q8TAQ2 SMARCC2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1091-1092 2 3.91e-03 100.0 1 0.57 175 READ, COAD CESC, BLCA, READ, COAD
ACTL9_ENST00000612068 Q8TC94 ACTL9 Actin-like protein 9 chr19 Not Cancer Driver No 374-391 18 3.91e-03 0.0 20 16.81 119 - LUSC, GBM, LUAD, KIRC, BRCA, LIHC, READ, COAD, SARC, SKCM, PAAD
WTAP_ENST00000621533 Q15007 WTAP Pre-mRNA-splicing regulator WTAP chr6 Not Cancer Driver No 156-164 9 3.92e-03 0.0 11 18.03 61 - BRCA, LUAD, PAAD, BLCA, PRAD, UCEC, KIRC
RUFY4_ENST00000344321 Q6ZNE9 RUFY4 RUN and FYVE domain-containing protein 4 chr2 Not Cancer Driver No 333-382 50 3.94e-03 100.0 23 29.87 77 SKCM LUAD, STAD, BRCA, GBM, PRAD, LIHC, SKCM, UCEC, CESC
PRSS48 Q7RTY5 PRSS48 Serine protease 48 chr4 Not Cancer Driver No 46-50 5 3.96e-03 0.0 10 15.15 66 CESC PRAD, CESC
NFE2_ENST00000312156 Q16621 NFE2 Transcription factor NF-E2 45 kDa subunit chr12 Not Cancer Driver No 157-171 15 3.96e-03 100.0 13 20.31 64 SKCM BRCA, BLCA, SKCM, LUAD, CESC, SARC
ANXA8L1 Q5VT79 ANXA8L1 Annexin A8-like protein 1 chr10 Not Cancer Driver No 309-324 16 3.97e-03 0.0 5 100.0 5 GBM LUSC, LUAD, BRCA, GBM
C10orf95 A0A1B0GTG0 C10orf95 Uncharacterized protein C10orf95 chr10 Not Cancer Driver No 39-39 1 3.97e-03 100.0 12 100.0 12 COAD, READ COAD, READ
TTLL11 Q8NHH1 TTLL11 Tubulin polyglutamylase TTLL11 chr9 Not Cancer Driver No 122-122 1 3.97e-03 100.0 0 0.0 99 READ COAD, READ
PARS2 Q7L3T8 PARS2 Probable proline--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 13-57 45 3.99e-03 78.26 17 34.0 50 - KIRC, COAD, UCEC, HNSC, LUSC, BRCA, SKCM, OV
MMP12 P39900 MMP12 Macrophage metalloelastase chr11 Not Cancer Driver No 102-166 65 4.00e-03 7.69 31 31.0 100 SKCM HNSC, UCEC, LGG, BLCA, SARC, STAD, LUAD, LUSC, PRAD, SKCM, KIRC
FAM83D Q9H4H8 FAM83D Protein FAM83D chr20 Not Cancer Driver No 458-512 55 4.00e-03 100.0 18 24.32 74 SKCM OV, KIRC, LUAD, HNSC, SKCM, CESC, UCEC, LUSC
OR6C1 Q96RD1 OR6C1 Olfactory receptor 6C1 chr12 Not Cancer Driver No 63-73 11 4.00e-03 0.0 18 22.5 80 SKCM SKCM, GBM, STAD, BLCA, UCEC, LUAD
FAM47A Q5JRC9 FAM47A Protein FAM47A chrX Not Cancer Driver No 365-378 14 4.01e-03 100.0 22 5.85 376 LUSC LUAD, GBM, LUSC, CESC, OV, HNSC, STAD, SKCM, PRAD
HS6ST1 O60243 HS6ST1 Heparan-sulfate 6-O-sulfotransferase 1 chr2 Not Cancer Driver No 371-378 8 4.02e-03 0.0 10 16.39 61 BRCA UCEC, STAD, BRCA, BLCA
GRIN2D O15399 GRIN2D Glutamate receptor ionotropic, NMDA 2D chr19 Not Cancer Driver No 546-599 54 4.04e-03 9.26 17 13.6 125 - LUAD, SARC, BLCA, GBM, KIRC, STAD, UCEC, CESC, SKCM, LUSC
PRSS36 Q5K4E3 PRSS36 Polyserase-2 chr16 Not Cancer Driver No 326-365 40 4.04e-03 5.0 14 16.47 85 - SKCM, LUSC, STAD, KIRC, BLCA, LUAD, UCEC
OR5B21 A6NL26 OR5B21 Olfactory receptor 5B21 chr11 Not Cancer Driver No 74-84 11 4.04e-03 0.0 13 19.12 68 LUAD READ, BLCA, COAD, SKCM, OV, LUSC, LUAD
FBN3_ENST00000601739 Q75N90 FBN3 Fibrillin-3 chr19 Not Cancer Driver No 2727-2774 48 4.06e-03 100.0 21 4.53 464 - SARC, GBM, THCA, BLCA, BRCA, LUAD, KIRC, LUSC, READ, SKCM, COAD
ZNF83_ENST00000536937 P51522 ZNF83 Zinc finger protein 83 chr19 Not Cancer Driver No 314-321 8 4.08e-03 0.0 10 12.2 82 BLCA, CESC STAD, BLCA, CESC
FLVCR2 Q9UPI3 FLVCR2 Feline leukemia virus subgroup C receptor-related protein 2 chr14 Not Cancer Driver No 13-62 50 4.10e-03 100.0 17 24.64 69 - OV, STAD, BLCA, BRCA, LAML, UCEC, SKCM, COAD
HAPLN4 Q86UW8 HAPLN4 Hyaluronan and proteoglycan link protein 4 chr19 Not Cancer Driver No 225-273 49 4.10e-03 44.0 23 38.33 60 LUSC UCEC, SKCM, HNSC, SARC, COAD, STAD, LUSC
SPERT Q8NA61 CBY2 Protein chibby homolog 2 chr13 Not Cancer Driver No 64-94 31 4.10e-03 100.0 22 19.47 113 - CESC, COAD, READ, SARC, GBM, SKCM, HNSC, LUAD, BLCA, STAD, LGG
PHF24 Q9UPV7 PHF24 PHD finger protein 24 chr9 Not Cancer Driver No 209-263 55 4.12e-03 7.27 32 30.77 104 SKCM BLCA, BRCA, READ, COAD, SKCM, LUSC, PAAD, LUAD, STAD, UCEC, KIRC
CBX4 O00257 CBX4 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 281-295 15 4.12e-03 100.0 21 25.93 81 BLCA LUAD, BLCA, SKCM
PRX Q9BXM0 PRX Periaxin chr19 Not Cancer Driver No 871-913 43 4.13e-03 100.0 19 8.92 213 - KIRC, SKCM, LIHC, OV, HNSC, BRCA, PAAD, LAML, BLCA, STAD, UCEC
TENM1_ENST00000371130 Q9UKZ4 TENM1 Teneurin-1 chrX Not Cancer Driver No 1200-1256 57 4.13e-03 100.0 30 4.12 728 SKCM UCEC, COT, THCA, KIRC, COAD, READ, LUAD, SKCM, BRCA, LUSC, STAD, SARC, HNSC, CESC
KCNQ4_ENST00000347132 P56696 KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 chr1 Not Cancer Driver No 582-597 16 4.14e-03 100.0 11 13.1 84 HNSC, SKCM LUAD, BRCA, HNSC, COAD, SKCM
CXCR1 P25024 CXCR1 C-X-C chemokine receptor type 1 chr2 Not Cancer Driver No 276-286 11 4.15e-03 0.0 13 17.81 73 - BLCA, LUSC, PAAD, LUAD, BRCA, UCEC, GBM, COAD
MAML3 Q96JK9 MAML3 Mastermind-like protein 3 chr4 Not Cancer Driver No 644-654 11 4.16e-03 100.0 6 4.72 127 - STAD, LUAD, BRCA, READ, COAD, UCEC
CRHR2_ENST00000471646 Q13324 CRHR2 Corticotropin-releasing factor receptor 2 chr7 Not Cancer Driver No 216-224 9 4.17e-03 0.0 13 16.46 79 COAD UCEC, CESC, LUSC, SKCM, KIRC, COAD
PDHB P11177 PDHB Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 316-336 21 4.18e-03 0.0 11 34.38 32 - CESC, STAD, BRCA, SARC, SKCM, LGG, BLCA
AVPR1A P37288 AVPR1A Vasopressin V1a receptor chr12 Not Cancer Driver No 223-234 12 4.18e-03 0.0 8 7.55 106 BLCA, LUAD BLCA, LGG, LUAD, COAD
MUC15_ENST00000455601 Q8N387 MUC15 Mucin-15 chr11 Not Cancer Driver No 324-331 8 4.19e-03 100.0 10 10.75 93 LUAD KIRC, LUAD, STAD, SKCM, LIHC, UCEC, OV
PEG10_ENST00000617526 Q86TG7 PEG10 Retrotransposon-derived protein PEG10 chr7 Not Cancer Driver No 159-175 17 4.22e-03 29.41 10 10.64 94 - HNSC, LGG, READ, PAAD, LUSC, BRCA, CESC, GBM
PRLHR_ENST00000636925 P49683 PRLHR Prolactin-releasing peptide receptor chr10 Not Cancer Driver No 283-289 7 4.22e-03 0.0 17 21.52 79 READ, COAD STAD, READ, LIHC, OV, COAD
OR9Q1_ENST00000612174 Q8NGQ5 OR9Q1 Olfactory receptor 9Q1 chr11 Not Cancer Driver No 21-32 12 4.22e-03 0.0 13 16.25 80 SKCM, KIRC SKCM, BLCA, STAD, KIRC, READ, PRAD
STOX1_ENST00000399169 Q6ZVD7 STOX1 Storkhead-box protein 1 chr10 Not Cancer Driver No 120-153 34 4.26e-03 0.0 18 14.52 124 - STAD, HNSC, LUAD, COAD, UCEC, SARC, LUSC, BRCA, SKCM, KIRC, BLCA
USP49 Q70CQ1 USP49 Ubiquitin carboxyl-terminal hydrolase 49 chr6 Not Cancer Driver No 44-59 16 4.27e-03 6.25 10 12.35 81 - STAD, READ, OV, COAD, LUAD, BRCA
CDH19 Q9H159 CDH19 Cadherin-19 chr18 Not Cancer Driver No 639-694 56 4.28e-03 96.43 29 14.57 199 - STAD, SARC, BLCA, GBM, LUAD, KIRC, LUSC, CESC, UCEC, SKCM, HNSC, OV
KIF25_ENST00000443060 Q9UIL4 KIF25 Kinesin-like protein KIF25 chr6 Not Cancer Driver No 3-10 8 4.29e-03 100.0 11 12.64 87 PRAD COAD, LGG, LUSC, UCEC, LUAD, OV, PRAD
SGK1_ENST00000237305 O00141 SGK1 Serine/threonine-protein kinase Sgk1 chr6 Census, Compendium Yes 343-393 51 4.30e-03 3.92 9 15.52 58 UCEC, COAD LUAD, UCEC, STAD, COAD, SKCM
KEAP1_ENST00000393623 Q14145 KEAP1 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 470-483 14 4.31e-03 0.0 20 8.37 239 LUAD LUSC, HNSC, BLCA, LUAD, SKCM, THCA, UCEC
CT47B1 P0C2W7 CT47B1 Cancer/testis antigen 47B chrX Not Cancer Driver No 249-259 11 4.32e-03 100.0 16 11.76 136 LUAD BRCA, COAD, LAML, HNSC, THCA, BLCA, SKCM, LUSC, LUAD
PRB2 P02812 PRB2 Basic salivary proline-rich protein 2 chr12 Not Cancer Driver No 100-108 9 4.32e-03 100.0 14 7.41 189 SKCM BRCA, LIHC, COAD, SKCM, LUSC, LUAD
GPR50 Q13585 GPR50 Melatonin-related receptor chrX Not Cancer Driver No 502-509 8 4.32e-03 100.0 9 5.11 176 COAD, OV COAD, OV, UCEC
COL6A5 A8TX70 COL6A5 Collagen alpha-5(VI) chain chr3 Not Cancer Driver No 23-80 58 4.33e-03 10.17 18 5.88 306 - READ, COAD, UCEC, HNSC, LUAD, SKCM, BLCA, BRCA, LUSC
CTNNA1 P35221 CTNNA1 Catenin alpha-1 chr5 Census Yes 775-811 37 4.35e-03 100.0 20 15.87 126 - KIRC, SARC, BRCA, UCEC, SKCM, STAD, COAD, LIHC, CESC, LUSC
RUSC1 Q9BVN2 RUSC1 AP-4 complex accessory subunit RUSC1 chr1 Not Cancer Driver No 849-886 38 4.35e-03 2.63 15 15.15 99 STAD OV, THCA, HNSC, GBM, KIRC, LUAD, STAD, COAD
ZNRF4 Q8WWF5 ZNRF4 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 153-169 17 4.35e-03 0.0 21 16.94 124 COAD HNSC, PRAD, STAD, BRCA, COAD, SKCM, READ, LIHC
NIT1 Q86X76 NIT1 Deaminated glutathione amidase chr1 Not Cancer Driver No 35-62 28 4.36e-03 35.71 13 31.71 41 LUAD, UCEC SKCM, LUSC, LUAD, BRCA, BLCA, UCEC
RASSF2 P50749 RASSF2 Ras association domain-containing protein 2 chr20 Not Cancer Driver No 150-155 6 4.38e-03 100.0 10 11.11 90 STAD LUAD, PRAD, UCEC, STAD, PAAD, BRCA
ZNF460 Q14592 ZNF460 Zinc finger protein 460 chr19 Not Cancer Driver No 274-284 11 4.38e-03 0.0 10 11.76 85 - LUSC, OV, READ, SKCM, BRCA, STAD
NIN Q8N4C6 NIN Ninein chr14 Census, Compendium Yes 439-474 36 4.38e-03 8.33 14 5.74 244 - COAD, BLCA, BRCA, SKCM, UCEC, HNSC, STAD
ARHGAP6 O43182 ARHGAP6 Rho GTPase-activating protein 6 chrX Not Cancer Driver No 553-586 34 4.39e-03 41.18 17 10.06 169 SKCM SKCM, STAD, HNSC, LUAD, UCEC, LUSC, OV, PAAD, SARC, CESC
OR52B2 Q96RD2 OR52B2 Olfactory receptor 52B2 chr11 Not Cancer Driver No 224-229 6 4.40e-03 0.0 12 13.95 86 SKCM LUSC, SKCM, UCEC, LAML, COAD
FAM83H Q6ZRV2 FAM83H Protein FAM83H chr8 Not Cancer Driver No 147-186 40 4.41e-03 0.0 16 10.6 151 STAD LUAD, UCEC, COAD, CESC, SKCM, BLCA, STAD
RPS18 P62269 RPS18 40S ribosomal protein S18 chr6 Not Cancer Driver No 77-77 1 4.45e-03 0.0 7 25.0 28 BLCA, PRAD BLCA, PRAD
NCAPH Q15003 NCAPH Condensin complex subunit 2 chr2 Not Cancer Driver No 530-538 9 4.45e-03 100.0 10 10.2 98 LAML BLCA, SKCM, OV, LUSC, LAML, LUAD
NPTX2 P47972 NPTX2 Neuronal pentraxin-2 chr7 Not Cancer Driver No 381-387 7 4.45e-03 0.0 10 12.82 78 - STAD, GBM, HNSC, LUAD, COAD, KIRC, UCEC
AVP P01185 AVP Vasopressin-neurophysin 2-copeptin chr20 Not Cancer Driver No 4-40 37 4.46e-03 51.35 12 85.71 14 STAD SKCM, STAD, COAD, READ, LUSC, THCA
CTRB2 Q6GPI1 CTRB2 Chymotrypsinogen B2 chr16 Not Cancer Driver No 222-263 42 4.46e-03 0.0 9 64.29 14 - LUSC, LUAD, BLCA, SKCM, HNSC, CESC, UCEC
HDDC3_ENST00000646620 Q8N4P3 HDDC3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 chr15 Not Cancer Driver No 70-106 37 4.46e-03 0.0 9 69.23 13 UCEC READ, LUSC, BRCA, LIHC, STAD, UCEC
CWC22 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog chr2 Not Cancer Driver No 38-69 32 4.49e-03 100.0 15 14.29 105 - LUAD, SKCM, STAD, LIHC, COAD, BRCA, UCEC, LUSC, HNSC, KIRC
OR52M1 Q8NGK5 OR52M1 Olfactory receptor 52M1 chr11 Not Cancer Driver No 144-150 7 4.49e-03 0.0 15 16.13 93 SKCM, UCEC LUAD, HNSC, SKCM, UCEC
SH3RF3 Q8TEJ3 SH3RF3 E3 ubiquitin-protein ligase SH3RF3 chr2 Not Cancer Driver No 238-268 31 4.49e-03 16.13 17 17.17 99 SKCM UCEC, LIHC, LUAD, LUSC, SKCM, OV, COAD, LAML
SYK_ENST00000375746 P43405 SYK Tyrosine-protein kinase SYK chr9 Census Yes 569-580 12 4.49e-03 0.0 10 10.42 96 SKCM HNSC, UCEC, LUSC, LIHC, SKCM
ANKRD40 Q6AI12 ANKRD40 Ankyrin repeat domain-containing protein 40 chr17 Not Cancer Driver No 99-106 8 4.49e-03 100.0 9 20.93 43 STAD READ, STAD, BRCA, BLCA, UCEC
SHISAL1 Q3SXP7 SHISAL1 Protein shisa-like-1 chr22 Not Cancer Driver No 140-154 15 4.50e-03 100.0 13 27.08 48 - CESC, UCEC, BRCA, READ, HNSC, SKCM, STAD
SPANXN2 Q5MJ10 SPANXN2 Sperm protein associated with the nucleus on the X chromosome N2 chrX Not Cancer Driver No 81-123 43 4.52e-03 100.0 43 39.81 108 SKCM GBM, LUAD, COAD, UCEC, HNSC, STAD, SKCM, LUSC, CESC, LGG, DLBC
SSX4B O60224 SSX4B Protein SSX4 chrX Not Cancer Driver No 72-81 10 4.53e-03 81.82 11 52.38 21 LUSC, STAD LUSC, STAD, LIHC, COAD
ABLIM2_ENST00000341937 Q6H8Q1 ABLIM2 Actin-binding LIM protein 2 chr4 Not Cancer Driver No 157-166 10 4.56e-03 10.0 10 9.9 101 SKCM STAD, BLCA, SKCM, OV, LUAD, UCEC
ZFR2 Q9UPR6 ZFR2 Zinc finger RNA-binding protein 2 chr19 Not Cancer Driver No 441-451 11 4.56e-03 72.73 12 10.53 114 SKCM HNSC, BLCA, BRCA, LUSC, LIHC, LUAD, SKCM
CRTAM O95727 CRTAM Cytotoxic and regulatory T-cell molecule chr11 Not Cancer Driver No 28-77 50 4.56e-03 0.0 19 28.36 67 SKCM LUSC, BRCA, LUAD, SKCM, CESC, STAD
MID2 Q9UJV3 MID2 Probable E3 ubiquitin-protein ligase MID2 chrX Not Cancer Driver No 116-127 12 4.57e-03 100.0 10 8.93 112 COAD, SKCM LUSC, LGG, COAD, SKCM
OR8K1 Q8NGG5 OR8K1 Olfactory receptor 8K1 chr11 Not Cancer Driver No 108-113 6 4.57e-03 0.0 10 9.71 103 STAD LUAD, LUSC, STAD, READ, KIRC
C4B_ENST00000425700 F5GXS0 C4B Complement C4-B chr6 Not Cancer Driver No 1111-1140 30 4.58e-03 100.0 9 25.0 36 SKCM SKCM, LUAD, OV, BLCA, COAD
GPR139 Q6DWJ6 GPR139 Probable G-protein coupled receptor 139 chr16 Not Cancer Driver No 214-224 11 4.58e-03 90.91 17 14.66 116 SKCM READ, COAD, SKCM, LUSC, LUAD, UCEC, STAD, CESC
PAX3_ENST00000350526 P23760 PAX3 Paired box protein Pax-3 chr2 Census Yes 411-424 14 4.58e-03 100.0 14 12.39 113 COAD HNSC, COAD, LUSC, READ, STAD, LIHC, GBM
OR2Z1 Q8NG97 OR2Z1 Olfactory receptor 2Z1 chr19 Not Cancer Driver No 163-167 5 4.59e-03 0.0 10 10.42 96 SKCM BRCA, SKCM
TMPRSS11E Q9UL52 TMPRSS11E Transmembrane protease serine 11E chr4 Not Cancer Driver No 250-261 12 4.61e-03 0.0 15 14.29 105 LUAD, SKCM STAD, LUAD, UCEC, LIHC, LGG, SKCM, LUSC
MAP3K6 O95382 MAP3K6 Mitogen-activated protein kinase kinase kinase 6 chr1 Not Cancer Driver No 616-626 11 4.62e-03 58.33 18 15.38 117 GBM COAD, GBM, LUAD
UGT1A8 Q9HAW9 UGT1A8 UDP-glucuronosyltransferase 1A8 chr2 Not Cancer Driver No 4-10 7 4.63e-03 100.0 10 9.01 111 SKCM LGG, PRAD, LUSC, GBM, LUAD, KIRC, SKCM
ALMS1 Q8TCU4 ALMS1 Alstrom syndrome protein 1 chr2 Not Cancer Driver No 27-28 2 4.63e-03 100.0 0 0.0 540 OV, READ OV, READ
FAM174B Q3ZCQ3 FAM174B Membrane protein FAM174B chr15 Compendium Yes 69-70 2 4.63e-03 100.0 0 0.0 17 READ, COAD READ, COAD
SLC29A4_ENST00000297195 Q7RTT9 SLC29A4 Equilibrative nucleoside transporter 4 chr7 Not Cancer Driver No 413-424 12 4.63e-03 0.0 13 13.83 94 GBM UCEC, GBM, LUAD, LUSC, SKCM
ONECUT1 Q9UBC0 ONECUT1 Hepatocyte nuclear factor 6 chr15 Not Cancer Driver No 318-368 51 4.64e-03 5.88 17 21.79 78 - HNSC, COAD, BRCA, UCEC, BLCA, SKCM, LUSC, STAD, PRAD, LUAD, GBM
CHST7 Q9NS84 CHST7 Carbohydrate sulfotransferase 7 chrX Not Cancer Driver No 150-193 44 4.64e-03 27.27 16 32.65 49 STAD BRCA, LUAD, BLCA, UCEC, STAD, SKCM, LIHC
FPR2 P25090 FPR2 N-formyl peptide receptor 2 chr19 Not Cancer Driver No 52-57 6 4.64e-03 0.0 10 10.42 96 GBM READ, BRCA, GBM, BLCA, STAD, LUSC, COAD
COL12A1 Q99715 COL12A1 Collagen alpha-1(XII) chain chr6 Not Cancer Driver No 2943-3001 59 4.66e-03 100.0 26 4.69 554 - BLCA, KIRC, OV, HNSC, BRCA, STAD, GBM, READ, LUSC, SKCM, UCEC
SURF2 Q15527 SURF2 Surfeit locus protein 2 chr9 Not Cancer Driver No 136-151 16 4.67e-03 100.0 9 33.33 27 LUSC HNSC, LUSC, BLCA, CESC, STAD, LUAD
OR4M2 Q8NGB6 OR4M2 Olfactory receptor 4M2 chr15 Not Cancer Driver No 262-273 12 4.68e-03 0.0 21 9.42 223 SKCM SKCM, PRAD, BLCA, LUSC, LUAD, STAD, COAD, HNSC, KIRC
TEKT4 Q8WW24 TEKT4 Tektin-4 chr2 Not Cancer Driver No 80-91 12 4.70e-03 0.0 21 19.81 106 READ, COAD SKCM, GBM, READ, LUSC, COAD, UCEC
HSD17B7 P56937 HSD17B7 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 chr1 Not Cancer Driver No 173-179 7 4.70e-03 0.0 7 21.21 33 KIRC, UCEC KIRC, HNSC, UCEC, PAAD
PPCS Q9HAB8 PPCS Phosphopantothenate--cysteine ligase chr1 Not Cancer Driver No 110-113 4 4.70e-03 0.0 7 17.95 39 BLCA LIHC, STAD, BRCA, BLCA
PXDNL A1KZ92 PXDNL Probable oxidoreductase PXDNL chr8 Not Cancer Driver No 848-872 25 4.71e-03 64.0 23 4.08 564 - BLCA, LUSC, LGG, DLBC, PAAD, LAML, STAD, LIHC, COAD, LUAD, UCEC, SKCM
VAMP5 O95183 VAMP5 Vesicle-associated membrane protein 5 chr2 Not Cancer Driver No 5-15 11 4.71e-03 0.0 9 52.94 17 BRCA, GBM, LGG HNSC, BRCA, LUAD, GBM, LGG
MTHFD1L_ENST00000367321 Q6UB35 MTHFD1L Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 Not Cancer Driver No 740-769 30 4.74e-03 0.0 13 11.11 117 - LUSC, OV, BRCA, STAD, BLCA, SKCM, HNSC, LUAD
AOC2 O75106 AOC2 Retina-specific copper amine oxidase chr17 Not Cancer Driver No 401-407 7 4.74e-03 0.0 10 8.62 116 GBM OV, GBM, COAD
CNOT3 O75175 CNOT3 CCR4-NOT transcription complex subunit 3 chr19 Census, Compendium Yes 12-20 9 4.74e-03 0.0 10 8.33 120 PRAD, BLCA PRAD, STAD, LGG, SKCM, BLCA
AATK Q6ZMQ8 AATK Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 699-709 11 4.75e-03 100.0 17 14.41 118 COAD, READ COAD, SKCM, LUAD, READ
KIF5B P33176 KIF5B Kinesin-1 heavy chain chr10 Census, Compendium Yes 75-87 13 4.75e-03 0.0 12 9.84 122 HNSC UCEC, HNSC, OV, LUSC, LUAD
NOX3 Q9HBY0 NOX3 NADPH oxidase 3 chr6 Not Cancer Driver No 400-408 9 4.75e-03 0.0 10 8.13 123 HNSC GBM, HNSC, LUAD, UCEC, SARC, LUSC
FLI1 Q01543 FLI1 Friend leukemia integration 1 transcription factor chr11 Census Yes 426-438 13 4.76e-03 100.0 12 11.43 105 SKCM LUSC, READ, LUAD, SKCM, GBM, COAD, UCEC
EEF1AKNMT Q8N6R0 METTL13 eEF1A lysine and N-terminal methyltransferase chr1 Not Cancer Driver No 367-412 46 4.76e-03 8.7 17 18.48 92 - COAD, HNSC, UCEC, BLCA, STAD, BRCA, LUAD, KIRC, SKCM, LUSC
ARHGAP9_ENST00000393791 Q9BRR9 ARHGAP9 Rho GTPase-activating protein 9 chr12 Not Cancer Driver No 66-70 5 4.77e-03 0.0 10 7.94 126 GBM COAD, GBM, BRCA, PRAD, UCEC, LUAD
ESR1_ENST00000206249 P03372 ESR1 Estrogen receptor chr6 Census, Compendium Yes 533-541 9 4.77e-03 100.0 12 9.52 126 UCEC UCEC, STAD, GBM, LUAD, LUSC
HTR7 P34969 HTR7 5-hydroxytryptamine receptor 7 chr10 Not Cancer Driver No 331-342 12 4.78e-03 0.0 18 17.48 103 - COAD, STAD, LUSC, LIHC, UCEC, KIRC, OV, LUAD
SLC5A5 Q92911 SLC5A5 Sodium/iodide cotransporter chr19 Not Cancer Driver No 561-576 16 4.78e-03 56.25 12 12.5 96 - LUSC, SKCM, COAD, PRAD, READ, UCEC, HNSC, KIRC, LGG, STAD, CESC
IPO5_ENST00000490680 O00410 IPO5 Importin-5 chr13 Not Cancer Driver No 348-355 8 4.78e-03 0.0 18 13.14 137 BLCA BLCA, OV, KIRC
NDN Q99608 NDN Necdin chr15 Not Cancer Driver No 203-211 9 4.78e-03 0.0 14 11.38 123 - LUAD, KIRC, GBM, LUSC, HNSC, SKCM, STAD, UCEC, COAD
UGT2B11 O75310 UGT2B11 UDP-glucuronosyltransferase 2B11 chr4 Not Cancer Driver No 148-162 15 4.78e-03 0.0 14 9.52 147 SKCM, GBM SARC, COAD, LUAD, SKCM, LAML, GBM
MMP9 P14780 MMP9 Matrix metalloproteinase-9 chr20 Not Cancer Driver No 398-408 11 4.79e-03 0.0 10 7.63 131 - READ, KIRC, SARC, STAD, LGG, GBM, OV
PAX1 P15863 PAX1 Paired box protein Pax-1 chr20 Not Cancer Driver No 330-337 8 4.80e-03 100.0 10 7.63 131 SKCM PRAD, SKCM, HNSC, LUAD, STAD, COAD
ATP13A1 Q9HD20 ATP13A1 Endoplasmic reticulum transmembrane helix translocase chr19 Not Cancer Driver No 921-933 13 4.81e-03 100.0 10 7.58 132 SKCM BLCA, OV, LGG, SKCM, STAD
MN1 Q10571 MN1 Transcriptional activator MN1 chr22 Census Yes 39-73 35 4.81e-03 100.0 14 9.4 149 - GBM, STAD, COAD, LUAD, PRAD, SKCM, OV, UCEC, CESC, LUSC
OR51S1 Q8NGJ8 OR51S1 Olfactory receptor 51S1 chr11 Not Cancer Driver No 234-242 9 4.81e-03 0.0 14 10.0 140 SKCM COAD, SKCM, LUSC, READ
DAO P14920 DAO D-amino-acid oxidase chr12 Not Cancer Driver No 281-288 8 4.81e-03 0.0 12 11.65 103 GBM LUAD, GBM, STAD, OV, SKCM, READ
GPR27 Q9NS67 GPR27 Probable G-protein coupled receptor 27 chr3 Not Cancer Driver No 307-313 7 4.81e-03 0.0 7 26.92 26 STAD LUAD, SKCM, STAD, HNSC, COAD
KBTBD13 C9JR72 KBTBD13 Kelch repeat and BTB domain-containing protein 13 chr15 Not Cancer Driver No 81-81 1 4.81e-03 0.0 16 40.0 40 READ, COAD READ, COAD
MED27 Q6P2C8 MED27 Mediator of RNA polymerase II transcription subunit 27 chr9 Not Cancer Driver No 294-298 5 4.81e-03 0.0 7 20.59 34 UCEC, KIRC LIHC, UCEC, KIRC, READ
SIGLEC7 Q9Y286 SIGLEC7 Sialic acid-binding Ig-like lectin 7 chr19 Not Cancer Driver No 118-128 11 4.83e-03 0.0 12 10.62 113 SKCM READ, UCEC, SARC, SKCM, STAD
SSTR4 P31391 SSTR4 Somatostatin receptor type 4 chr20 Not Cancer Driver No 151-154 4 4.84e-03 0.0 10 7.75 129 LUAD LUSC, UCEC, COAD, PRAD, CESC, GBM, LUAD
HNRNPD Q14103 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 258-267 10 4.84e-03 90.0 5 12.82 39 SKCM, STAD, UCEC SKCM, STAD, UCEC, BLCA
ZSWIM4 Q9H7M6 ZSWIM4 Zinc finger SWIM domain-containing protein 4 chr19 Not Cancer Driver No 93-103 11 4.85e-03 54.55 12 8.89 135 UCEC KIRC, UCEC, BLCA, CESC, SKCM
ACMSD Q8TDX5 ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase chr2 Not Cancer Driver No 113-159 47 4.85e-03 0.0 17 26.15 65 SKCM UCEC, LUSC, KIRC, SKCM, COAD, GBM, READ
CACNG3 O60359 CACNG3 Voltage-dependent calcium channel gamma-3 subunit chr16 Not Cancer Driver No 311-314 4 4.86e-03 100.0 10 7.94 126 SKCM, LUSC SKCM, LUSC, GBM, UCEC, LGG, LUAD
PABPN1 Q86U42 PABPN1 Polyadenylate-binding protein 2 chr14 Not Cancer Driver No 268-304 37 4.86e-03 100.0 14 51.85 27 LUAD STAD, UCEC, OV, READ, BLCA, LUSC, CESC, HNSC, SKCM, LUAD
ADH1B P00325 ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B chr4 Not Cancer Driver No 257-266 10 4.87e-03 0.0 14 12.84 109 SKCM UCEC, SKCM
NPR1 P16066 NPR1 Atrial natriuretic peptide receptor 1 chr1 Not Cancer Driver No 796-802 7 4.88e-03 0.0 10 7.04 142 GBM COAD, BRCA, READ, LUAD, GBM, THCA, STAD
SLAMF7 Q9NQ25 SLAMF7 SLAM family member 7 chr1 Not Cancer Driver No 232-283 52 4.88e-03 28.3 24 36.36 66 - BRCA, LIHC, GBM, BLCA, UCEC, SKCM, LUAD, LUSC, STAD
TSSK3 Q96PN8 TSSK3 Testis-specific serine/threonine-protein kinase 3 chr1 Not Cancer Driver No 116-127 12 4.89e-03 0.0 10 33.33 30 - SKCM, BRCA, BLCA, OV, GBM, UCEC, STAD, COAD
ZCRB1 Q8TBF4 ZCRB1 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 chr12 Compendium Yes 73-78 6 4.89e-03 0.0 9 31.03 29 LAML LGG, GBM, STAD, LAML, OV
ELN P15502 ELN Elastin chr7 Census, Compendium Yes 156-165 10 4.89e-03 100.0 10 7.94 126 SKCM THCA, LUAD, STAD, UCEC, LIHC, SKCM, GBM
CATSPER1 Q8NEC5 CATSPER1 Cation channel sperm-associated protein 1 chr11 Not Cancer Driver No 163-171 9 4.90e-03 100.0 10 7.25 138 - COAD, OV, SKCM, LUSC, UCEC, HNSC, READ, BLCA
GABRA3_ENST00000535043 P34903 GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 chrX Not Cancer Driver No 73-77 5 4.91e-03 0.0 12 8.82 136 SKCM, UCEC HNSC, SKCM, READ, LUAD, COAD, UCEC
DTX1 Q86Y01 DTX1 E3 ubiquitin-protein ligase DTX1 chr12 Compendium Yes 476-488 13 4.92e-03 0.0 14 12.96 108 SKCM BLCA, STAD, HNSC, SKCM, LUSC, COAD
SSPO A2VEC9 SSPOP SCO-spondin chr7 Not Cancer Driver No 2196-2244 49 4.92e-03 100.0 20 2.65 756 SKCM KIRC, LUAD, UCEC, GBM, LUSC, PRAD, OV, COAD, SKCM, HNSC, STAD
HSF2BP O75031 HSF2BP Heat shock factor 2-binding protein chr21 Not Cancer Driver No 292-319 28 4.95e-03 0.0 11 21.15 52 - STAD, LGG, READ, UCEC, GBM, LUAD, SARC, SKCM
SV2C Q496J9 SV2C Synaptic vesicle glycoprotein 2C chr5 Not Cancer Driver No 404-411 8 4.95e-03 0.0 12 7.55 159 SKCM LUAD, COAD, KIRC, GBM, LUSC, SKCM
JPH2 Q9BR39 JPH2 Junctophilin-2 chr20 Not Cancer Driver No 307-315 9 4.96e-03 0.0 17 12.32 138 - LUAD, BRCA, STAD, GBM, SKCM, LUSC
EFCAB5 A4FU69 EFCAB5 EF-hand calcium-binding domain-containing protein 5 chr17 Not Cancer Driver No 598-637 40 4.96e-03 100.0 15 7.81 192 - BLCA, SKCM, HNSC, OV, LUAD, UCEC, BRCA, THCA
VWA5A O00534 VWA5A von Willebrand factor A domain-containing protein 5A chr11 Not Cancer Driver No 631-640 10 4.97e-03 100.0 11 7.48 147 SKCM LUSC, STAD, SKCM, UCEC, BLCA
DDR1_ENST00000324771 Q08345 DDR1 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 514-533 20 4.98e-03 100.0 15 12.2 123 - READ, SKCM, LIHC, OV, UCEC, STAD, BLCA, LUSC
SPTLC3 Q9NUV7 SPTLC3 Serine palmitoyltransferase 3 chr20 Not Cancer Driver No 91-102 12 4.98e-03 0.0 16 11.68 137 SKCM UCEC, SKCM, GBM
TRIM49 P0CI25 TRIM49 Tripartite motif-containing protein 49 chr11 Not Cancer Driver No 323-332 10 4.98e-03 50.0 12 9.84 122 STAD, LUSC COAD, LUAD, STAD, LIHC, BLCA, LUSC
KRTAP5-10 Q6L8G5 KRTAP5-10 Keratin-associated protein 5-10 chr11 Not Cancer Driver No 83-97 15 4.98e-03 100.0 17 26.98 63 SKCM LUSC, LUAD, STAD, SKCM, BRCA
GALNT8 Q9NY28 GALNT8 Probable polypeptide N-acetylgalactosaminyltransferase 8 chr12 Not Cancer Driver No 294-299 6 4.98e-03 0.0 11 6.55 168 GBM GBM, OV, LUAD, SKCM, CESC, KICH, LUSC
OR1S1 Q8NH92 OR1S1 Olfactory receptor 1S1 chr11 Not Cancer Driver No 147-155 9 4.98e-03 0.0 14 9.59 146 CESC CESC, UCEC, LUAD, LGG, SKCM
PRKG1_ENST00000401604 Q13976 PRKG1 cGMP-dependent protein kinase 1 chr10 Not Cancer Driver No 136-150 15 5.00e-03 0.0 14 8.38 167 LUAD HNSC, LUAD, BRCA, LUSC, SKCM
FBXW10 Q5XX13 FBXW10 F-box/WD repeat-containing protein 10 chr17 Not Cancer Driver No 245-253 9 5.02e-03 100.0 10 5.88 170 UCEC, SKCM LIHC, UCEC, SKCM
VPS50 Q96JG6 VPS50 Syndetin chr7 Not Cancer Driver No 304-308 5 5.02e-03 80.0 11 6.29 175 GBM GBM, LIHC
TGM7 Q96PF1 TGM7 Protein-glutamine gamma-glutamyltransferase Z chr15 Not Cancer Driver No 577-591 15 5.02e-03 0.0 13 10.83 120 - BLCA, COAD, UCEC, COT, GBM, SKCM, READ, BRCA, OV
CDH1 P12830 CDH1 Cadherin-1 chr16 Census, Compendium Yes 243-260 18 5.02e-03 11.11 14 9.27 151 BRCA, STAD BRCA, BLCA, STAD, PRAD
KCNV1 Q6PIU1 KCNV1 Potassium voltage-gated channel subfamily V member 1 chr8 Not Cancer Driver No 260-272 13 5.02e-03 0.0 15 10.2 147 - COAD, HNSC, READ, STAD, SKCM, BRCA, LGG, LUSC, PRAD
MPDZ O75970 MPDZ Multiple PDZ domain protein chr9 Not Cancer Driver No 1350-1398 49 5.03e-03 0.0 12 4.17 288 READ LUAD, READ, THCA, BLCA, LGG, KIRC, LUSC
CEP170B_ENST00000556508 Q9Y4F5 CEP170B Centrosomal protein of 170 kDa protein B chr14 Not Cancer Driver No 1197-1231 35 5.03e-03 100.0 12 9.09 132 SKCM LUAD, CESC, LUSC, SKCM, UCEC, HNSC, BRCA
HHIP Q96QV1 HHIP Hedgehog-interacting protein chr4 Not Cancer Driver No 39-55 17 5.03e-03 100.0 15 10.0 150 OV UCEC, PRAD, OV, LUSC, LIHC, BLCA, SARC, LUAD
SOGA3 Q5TF21 SOGA3 Protein SOGA3 chr6 Not Cancer Driver No 837-847 11 5.03e-03 0.0 12 6.67 180 COAD SKCM, PAAD, STAD, CESC, COAD, BLCA
UHRF1BP1 Q6BDS2 UHRF1BP1 UHRF1-binding protein 1 chr6 Not Cancer Driver No 721-733 13 5.03e-03 0.0 10 5.85 171 SKCM GBM, SKCM, CESC, HNSC, BRCA, COAD
PXT1 Q8NFP0 PXT1 Peroxisomal testis-specific protein 1 chr6 Not Cancer Driver No 88-111 24 5.05e-03 45.83 9 64.29 14 SKCM SKCM, BLCA, SARC, LUAD, LIHC
ADGRV1_ENST00000645211 Q8WXG9 ADGRV1 Adhesion G-protein coupled receptor V1 chr5 Not Cancer Driver No 2110-2149 40 5.06e-03 100.0 22 1.91 1149 SKCM UCEC, HNSC, SKCM, PRAD, KICH, CESC, BRCA, GBM, LUAD
NUP62 P37198 NUP62 Nuclear pore glycoprotein p62 chr19 Not Cancer Driver No 279-283 5 5.06e-03 100.0 8 10.13 79 STAD, COAD, OV, UCEC STAD, COAD, OV, UCEC
DRD5 P21918 DRD5 D(1B) dopamine receptor chr4 Not Cancer Driver No 275-285 11 5.06e-03 100.0 17 9.83 173 GBM LUAD, LUSC, PRAD, READ, SKCM, GBM, BLCA
NUPL2 O15504 NUP42 Nucleoporin NUP42 chr7 Not Cancer Driver No 24-36 13 5.07e-03 100.0 5 8.2 61 COAD, KIRC READ, SKCM, COAD, STAD, UCEC, KIRC
FAM83B Q5T0W9 FAM83B Protein FAM83B chr6 Not Cancer Driver No 870-887 18 5.07e-03 100.0 21 6.54 321 SKCM, LUAD PRAD, SARC, KIRC, SKCM, LUAD, BRCA
RUNX1T1_ENST00000614812 Q06455 RUNX1T1 Protein CBFA2T1 chr8 Census, Compendium Yes 234-243 10 5.07e-03 100.0 28 9.52 294 SKCM SKCM, GBM, LUSC, UCEC, HNSC, BLCA
NTM_ENST00000374786 Q9P121 NTM Neurotrimin chr11 Not Cancer Driver No 209-215 7 5.09e-03 0.0 13 10.0 130 READ COAD, UCEC, BRCA, LUSC, STAD, PRAD, READ, LUAD
ZNF679 Q8IYX0 ZNF679 Zinc finger protein 679 chr7 Not Cancer Driver No 10-29 20 5.09e-03 40.0 20 11.98 167 SKCM KIRC, OV, BLCA, LUSC, SKCM, LGG, UCEC, LIHC, BRCA
ANKRD36 A6QL64 ANKRD36 Ankyrin repeat domain-containing protein 36A chr2 Not Cancer Driver No 922-936 15 5.10e-03 100.0 11 5.7 193 STAD SKCM, CESC, UCEC, BRCA, BLCA, STAD, LUAD
CTAGE4 Q8IX94 CTAGE4 cTAGE family member 4 chr7 Not Cancer Driver No 695-707 13 5.10e-03 100.0 7 19.44 36 LUAD, SKCM LUAD, GBM, SKCM, UCEC
LTB4R_ENST00000396782 Q15722 LTB4R Leukotriene B4 receptor 1 chr14 Not Cancer Driver No 207-212 6 5.10e-03 33.33 7 20.59 34 SKCM, LUAD, GBM SKCM, LUAD, GBM
CD1E P15812 CD1E T-cell surface glycoprotein CD1e, membrane-associated chr1 Not Cancer Driver No 83-86 4 5.12e-03 0.0 10 6.29 159 STAD READ, STAD, LUSC, SKCM
FAM184A Q8NB25 FAM184A Protein FAM184A chr6 Not Cancer Driver No 721-732 12 5.12e-03 0.0 11 5.58 197 SKCM BRCA, SKCM, OV, LUAD, GBM
EMX1 Q04741 EMX1 Homeobox protein EMX1 chr2 Not Cancer Driver No 256-273 18 5.12e-03 100.0 10 38.46 26 - UCEC, SKCM, STAD, KIRC, PRAD, LUAD, COAD
DNAH5 Q8TE73 DNAH5 Dynein axonemal heavy chain 5 chr5 Not Cancer Driver No 3227-3245 19 5.12e-03 100.0 19 1.31 1446 SKCM LGG, LUAD, OV, SKCM, LUSC, STAD
IRAK3 Q9Y616 IRAK3 Interleukin-1 receptor-associated kinase 3 chr12 Not Cancer Driver No 409-444 36 5.13e-03 0.0 17 16.35 104 SKCM BLCA, UCEC, BRCA, HNSC, CESC, COAD, OV, SKCM, THCA, KIRC
AC134980.3 A0A126GVN2 OR4N4 Olfactory receptor chr15 Not Cancer Driver No 41-43 3 5.14e-03 100.0 14 7.65 183 SKCM HNSC, SKCM, UCEC
ADAM22 Q9P0K1 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 chr7 Not Cancer Driver No 255-260 6 5.14e-03 0.0 10 4.9 204 SKCM OV, STAD, SKCM, UCEC, BLCA
OR4N4 Q8N0Y3 OR4N4 Olfactory receptor 4N4 chr15 Not Cancer Driver No 41-43 3 5.14e-03 0.0 14 7.65 183 SKCM UCEC, SKCM, HNSC
ALG13 Q9NP73 ALG13 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 chrX Not Cancer Driver No 942-945 4 5.14e-03 100.0 3 1.83 164 CESC, READ CESC, SKCM, READ
ABI1 Q8IZP0 ABI1 Abl interactor 1 chr10 Census, Compendium Yes 266-309 44 5.14e-03 100.0 13 23.64 55 - CESC, BLCA, SKCM, KIRC, READ, LUSC, BRCA, HNSC
SH2D5 Q6ZV89 SH2D5 SH2 domain-containing protein 5 chr1 Not Cancer Driver No 236-271 36 5.14e-03 100.0 13 26.0 50 SKCM LIHC, READ, STAD, PAAD, CESC, OV, LUAD, SKCM
CPSF6_ENST00000435070 Q16630 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 538-549 12 5.17e-03 100.0 6 7.06 85 UCEC BRCA, SKCM, OV, READ, UCEC
PCNX3 Q9H6A9 PCNX3 Pecanex-like protein 3 chr11 Not Cancer Driver No 1689-1735 47 5.17e-03 10.64 15 8.11 185 - STAD, SKCM, LUAD, HNSC, LIHC, SARC, CESC, KIRC, UCEC, LUSC
CYFIP2 Q96F07 CYFIP2 Cytoplasmic FMR1-interacting protein 2 chr5 Not Cancer Driver No 1066-1077 12 5.18e-03 0.0 11 5.19 212 UCEC SKCM, KIRC, LUAD, OV, UCEC, STAD
ERICH3 Q5RHP9 ERICH3 Glutamate-rich protein 3 chr1 Not Cancer Driver No 1098-1152 55 5.18e-03 100.0 41 6.82 601 SKCM LUSC, CESC, LAML, LUAD, PAAD, BLCA, SKCM, STAD, BRCA
ACE P12821 ACE Angiotensin-converting enzyme chr17 Not Cancer Driver No 785-796 12 5.18e-03 0.0 10 4.9 204 OV OV, BLCA, SKCM, GBM, THCA, LIHC
BMPER Q8N8U9 BMPER BMP-binding endothelial regulator protein chr7 Not Cancer Driver No 632-644 13 5.18e-03 38.46 15 7.58 198 SKCM LUAD, LUSC, HNSC, READ, BLCA, SKCM
MIA2_ENST00000640607 Q96PC5 MIA2 Melanoma inhibitory activity protein 2 chr14 Not Cancer Driver No 552-562 11 5.19e-03 100.0 12 5.53 217 SKCM CESC, BRCA, LUAD, UCEC, READ, SKCM
FABP2 P12104 FABP2 Fatty acid-binding protein, intestinal chr4 Not Cancer Driver No 64-104 41 5.19e-03 0.0 16 64.0 25 SKCM OV, SKCM, READ, HNSC, STAD, COAD, LIHC
ROBO3 Q96MS0 ROBO3 Roundabout homolog 3 chr11 Not Cancer Driver No 534-545 12 5.20e-03 66.67 11 5.29 208 LUSC THCA, SARC, CESC, LUSC, LUAD, LGG, SKCM
MEFV O15553 MEFV Pyrin chr16 Not Cancer Driver No 202-204 3 5.21e-03 100.0 17 8.06 211 READ, COAD HNSC, STAD, READ, COAD, LUAD
PABPC1 P11940 PABPC1 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 405-414 10 5.21e-03 100.0 6 5.94 101 BLCA, KIRC BLCA, LUSC, KIRC, UCEC
KIT P10721 KIT Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 636-642 7 5.22e-03 0.0 10 4.42 226 SKCM STAD, SKCM, OV
PCDHGA7 Q9Y5G6 PCDHGA7 Protocadherin gamma-A7 chr5 Not Cancer Driver No 151-156 6 5.22e-03 0.0 11 5.05 218 - UCEC, COAD, BLCA, LUSC, SKCM, BRCA
CCDC144A A2RUR9 CCDC144A Coiled-coil domain-containing protein 144A chr17 Not Cancer Driver No 1194-1216 23 5.22e-03 0.0 15 8.2 183 SKCM SKCM, UCEC, PRAD, BRCA, BLCA, OV
KIDINS220 Q9ULH0 KIDINS220 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1075-1086 12 5.24e-03 100.0 10 4.07 246 HNSC, LUAD HNSC, UCEC, OV, SKCM, LUAD, DLBC
CDH22 Q9UJ99 CDH22 Cadherin-22 chr20 Not Cancer Driver No 368-381 14 5.24e-03 35.71 12 8.28 145 LUSC, STAD LUSC, LUAD, STAD, LIHC, UCEC, COAD
CORO7 P57737 CORO7 Coronin-7 chr16 Not Cancer Driver No 429-434 6 5.25e-03 100.0 6 5.56 108 SKCM SKCM, BLCA
JRK_ENST00000571961 O75564 JRK Jerky protein homolog chr8 Not Cancer Driver No 64-107 44 5.26e-03 40.0 14 24.14 58 UCEC, LUAD HNSC, UCEC, OV, BLCA, LIHC, STAD, LUAD
BNC2 Q6ZN30 BNC2 Zinc finger protein basonuclin-2 chr9 Not Cancer Driver No 727-735 9 5.26e-03 100.0 12 4.96 242 STAD PAAD, THCA, SARC, SKCM, OV, STAD, HNSC
ADAMTS14_ENST00000373207 Q8WXS8 ADAMTS14 A disintegrin and metalloproteinase with thrombospondin motifs 14 chr10 Not Cancer Driver No 267-273 7 5.27e-03 0.0 11 4.82 228 SKCM LIHC, HNSC, SKCM, READ, STAD, UCEC, OV, LUAD
POTEH Q6S545 POTEH POTE ankyrin domain family member H chr22 Not Cancer Driver No 70-73 4 5.29e-03 100.0 10 4.5 222 LUAD LUSC, BLCA, LUAD, SKCM, KIRC, PRAD
TSC1 Q92574 TSC1 Hamartin chr9 Census, Compendium Yes 178-193 16 5.29e-03 0.0 5 3.65 137 BLCA SKCM, LUAD, BLCA, READ
GOLGA6C A6NDK9 GOLGA6C Golgin subfamily A member 6C chr15 Not Cancer Driver No 213-245 33 5.29e-03 0.0 13 39.39 33 - GBM, CESC, LGG, UCEC, SKCM, HNSC, STAD
F13B P05160 F13B Coagulation factor XIII B chain chr1 Not Cancer Driver No 433-446 14 5.30e-03 0.0 16 7.69 208 SKCM LUAD, HNSC, COAD, LUSC, KIRC, BRCA, SKCM
TRIM58 Q8NG06 TRIM58 E3 ubiquitin-protein ligase TRIM58 chr1 Not Cancer Driver No 294-303 10 5.30e-03 0.0 16 7.8 205 LUSC BRCA, SKCM, GBM, LUSC, COAD, HNSC, LIHC
LILRB5_ENST00000316219 O75023 LILRB5 Leukocyte immunoglobulin-like receptor subfamily B member 5 chr19 Not Cancer Driver No 492-501 10 5.30e-03 100.0 14 8.92 157 LUAD GBM, LUSC, LUAD, BRCA, UCEC, READ, SKCM, HNSC, STAD
KCNQ5_ENST00000370398 Q9NR82 KCNQ5 Potassium voltage-gated channel subfamily KQT member 5 chr6 Not Cancer Driver No 241-247 7 5.30e-03 0.0 12 4.96 242 - STAD, LUAD, LUSC, SKCM, HNSC, GBM, LIHC, OV, READ
TP63 Q9H3D4 TP63 Tumor protein 63 chr3 Census, Compendium Yes 376-379 4 5.31e-03 100.0 12 5.24 229 SKCM STAD, KIRC, SKCM
LPAR5 Q9H1C0 LPAR5 Lysophosphatidic acid receptor 5 chr12 Not Cancer Driver No 23-66 44 5.32e-03 0.0 17 42.5 40 - GBM, OV, CESC, UCEC, THCA, COAD, BRCA, STAD, LIHC
TNXB_ENST00000375244 P22105 TNXB Tenascin-X chr6 Not Cancer Driver No 994-1006 13 5.33e-03 100.0 9 1.35 666 BLCA COAD, BLCA, SKCM, BRCA, STAD, LGG, LUSC
KDM5C P41229 KDM5C Lysine-specific demethylase 5C chrX Census, Compendium Yes 504-512 9 5.34e-03 0.0 5 2.99 167 OV STAD, OV, KIRC, HNSC, KICH, LUAD
CDH6 P55285 CDH6 Cadherin-6 chr5 Not Cancer Driver No 524-528 5 5.34e-03 0.0 12 4.78 251 SKCM BLCA, SKCM, PRAD
DSPP_ENST00000282478 Q9NZW4 DSPP Dentin sialophosphoprotein chr4 Not Cancer Driver No 1170-1179 10 5.34e-03 100.0 7 3.24 216 READ, UCEC READ, UCEC, BRCA, SARC
LRRC61_ENST00000323078 Q9BV99 LRRC61 Leucine-rich repeat-containing protein 61 chr7 Not Cancer Driver No 143-144 2 5.35e-03 0.0 10 25.0 40 COAD, SKCM COAD, READ, SKCM, STAD, HNSC
ODF4 Q2M2E3 ODF4 Outer dense fiber protein 4 chr17 Not Cancer Driver No 61-61 1 5.35e-03 100.0 7 15.91 44 GBM LUSC, GBM
MUC5AC P98088 MUC5AC Mucin-5AC chr11 Not Cancer Driver No 298-333 36 5.35e-03 100.0 11 4.51 244 LUSC UCEC, LUSC, BLCA, THCA, HNSC, GBM, LUAD
PBRM1_ENST00000296302 Q86U86 PBRM1 Protein polybromo-1 chr3 Census, Compendium Yes 1274-1287 14 5.36e-03 0.0 7 3.32 211 KIRC CESC, LIHC, BLCA, KIRC, PAAD
MYO3B Q8WXR4 MYO3B Myosin-IIIb chr2 Not Cancer Driver No 397-407 11 5.37e-03 0.0 6 2.44 246 SKCM, OV SKCM, COT, OV
MYO5B Q9ULV0 MYO5B Unconventional myosin-Vb chr18 Not Cancer Driver No 509-519 11 5.37e-03 9.09 10 3.72 269 SKCM BRCA, SKCM, STAD, KIRC
PTPRN2 Q92932 PTPRN2 Receptor-type tyrosine-protein phosphatase N2 chr7 Not Cancer Driver No 133-137 5 5.37e-03 100.0 12 4.33 277 SKCM UCEC, SKCM, LUSC, LUAD, KIRC, COAD
ZNF676 Q8N7Q3 ZNF676 Zinc finger protein 676 chr19 Not Cancer Driver No 246-248 3 5.37e-03 0.0 10 3.73 268 SKCM LUAD, STAD, HNSC, SKCM
CYP3A7 P24462 CYP3A7 Cytochrome P450 3A7 chr7 Not Cancer Driver No 158-165 8 5.38e-03 0.0 8 8.79 91 BLCA SKCM, BLCA, SARC, LIHC, BRCA
ADAMTS9 Q9P2N4 ADAMTS9 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 Not Cancer Driver No 1804-1815 12 5.38e-03 8.33 11 3.82 288 - COAD, LUSC, LGG, PAAD, PRAD, UCEC, SKCM, LUAD
PCDHA10 Q9Y5I2 PCDHA10 Protocadherin alpha-10 chr5 Not Cancer Driver No 534-539 6 5.38e-03 0.0 10 3.5 286 - LUSC, UCEC, COAD, LGG, READ, GBM, STAD, KIRC, LUAD
SPTA1_ENST00000368147 P02549 SPTA1 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1801-1806 6 5.38e-03 0.0 9 0.84 1075 LUSC STAD, BRCA, LIHC, OV, LUSC, LUAD
CFAP47 Q6ZTR5 CFAP47 Cilia- and flagella-associated protein 47 chrX Not Cancer Driver No 1680-1743 64 5.39e-03 100.0 24 5.44 441 - READ, BRCA, GBM, LUAD, HNSC, SKCM, LAML, LIHC, COAD, SARC, UCEC, LUSC
FSHR P23945 FSHR Follicle-stimulating hormone receptor chr2 Not Cancer Driver No 38-50 13 5.39e-03 0.0 14 6.17 227 LUSC, SKCM OV, LUSC, SKCM, HNSC
NBPF10 Q6P3W6 NBPF10 Neuroblastoma breakpoint family member 10 chr1 Not Cancer Driver No 121-129 9 5.40e-03 100.0 10 3.7 270 KIRC, LUAD SKCM, PRAD, KIRC, LUAD
KCNA6 P17658 KCNA6 Potassium voltage-gated channel subfamily A member 6 chr12 Not Cancer Driver No 241-248 8 5.42e-03 100.0 12 6.74 178 SKCM SKCM, LUAD, BLCA, PRAD
SPOP O43791 SPOP Speckle-type POZ protein chr17 Census, Compendium Yes 45-50 6 5.42e-03 0.0 13 8.84 147 UCEC SKCM, STAD, BLCA, UCEC
CLEC10A Q8IUN9 CLEC10A C-type lectin domain family 10 member A chr17 Not Cancer Driver No 250-253 4 5.42e-03 0.0 7 14.89 47 SKCM UCEC, SKCM, LUSC, BRCA
IFNA10 P01566 IFNA10 Interferon alpha-10 chr9 Not Cancer Driver No 79-80 2 5.42e-03 0.0 7 17.07 41 GBM, LUSC GBM, LUSC
ZC3H12D A2A288 ZC3H12D Probable ribonuclease ZC3H12D chr6 Not Cancer Driver No 404-405 2 5.42e-03 100.0 13 23.21 56 READ LAML, READ, COAD
CD177 Q8N6Q3 CD177 CD177 antigen chr19 Not Cancer Driver No 391-431 41 5.42e-03 85.71 24 32.88 73 SKCM STAD, BLCA, LUSC, BRCA, CESC, KIRC, OV, SKCM, LUAD
ADAM7 Q9H2U9 ADAM7 Disintegrin and metalloproteinase domain-containing protein 7 chr8 Not Cancer Driver No 213-225 13 5.42e-03 7.69 16 6.64 241 SKCM SKCM, STAD, COAD
DLC1 Q96QB1 DLC1 Rho GTPase-activating protein 7 chr8 Not Cancer Driver No 741-747 7 5.43e-03 100.0 10 3.0 333 - LGG, COAD, PRAD, SKCM, THCA, LUAD, BLCA
SRRM3 A0A087WXA3 SRRM3 Serine/arginine repetitive matrix protein 3 chr7 Not Cancer Driver No 210-248 39 5.45e-03 100.0 12 30.77 39 HNSC LGG, SKCM, HNSC, LIHC, BLCA, COAD, LUAD
MYH1 P12882 MYH1 Myosin-1 chr17 Not Cancer Driver No 1125-1140 16 5.46e-03 100.0 17 3.1 548 LUSC, SKCM LAML, LGG, LUSC, LIHC, STAD, SKCM, HNSC, UCEC
ERBB3 P21860 ERBB3 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 215-221 7 5.46e-03 0.0 10 3.36 298 UCEC HNSC, SKCM, CESC, COAD, UCEC
ERBB3 P21860 ERBB3 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 292-298 7 5.46e-03 0.0 10 3.36 298 UCEC UCEC, STAD, PRAD, BLCA, BRCA
TIAM1 Q13009 TIAM1 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 1382-1386 5 5.47e-03 0.0 10 2.67 374 GBM UCEC, GBM
ARHGAP35_ENST00000614079 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 chr19 Census, Compendium Yes 1309-1334 26 5.47e-03 0.0 14 5.47 256 - LUSC, BRCA, SKCM, SARC, BLCA, HNSC, UCEC, READ, STAD
CNTNAP2 Q9UHC6 CNTNAP2 Contactin-associated protein-like 2 chr7 Census Yes 83-95 13 5.47e-03 0.0 17 2.97 573 LUAD READ, LUSC, STAD, COAD, BLCA, LIHC, LUAD, GBM, SKCM
NPAP1 Q9NZP6 NPAP1 Nuclear pore-associated protein 1 chr15 Not Cancer Driver No 163-173 11 5.48e-03 100.0 19 3.33 570 LUAD, SKCM GBM, LUAD, LUSC, SKCM
SCN7A_ENST00000409855 Q01118 SCN7A Sodium channel protein type 7 subunit alpha chr2 Not Cancer Driver No 903-907 5 5.48e-03 100.0 11 2.77 397 - BRCA, SKCM, HNSC, READ, COAD, LUSC
SLIT3_ENST00000519560 O75094 SLIT3 Slit homolog 3 protein chr5 Not Cancer Driver No 152-158 7 5.48e-03 0.0 12 3.41 352 LUAD LGG, LUAD, COAD, SKCM, GBM, KIRC
KMT5A Q9NQR1-2 KMT5A Isoform 2 of N-lysine methyltransferase KMT5A chr12 Not Cancer Driver No 266-268 3 5.49e-03 100.0 7 17.07 41 GBM UCEC, GBM
MYBPC2 Q14324 MYBPC2 Myosin-binding protein C, fast-type chr19 Not Cancer Driver No 639-654 16 5.49e-03 0.0 16 7.88 203 UCEC LIHC, SKCM, STAD, CESC, UCEC, LUSC
ARFGEF3 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 chr6 Not Cancer Driver No 1925-1954 30 5.50e-03 100.0 14 5.32 263 SKCM BLCA, LIHC, SKCM, LUSC
GLI3 P10071 GLI3 Transcriptional activator GLI3 chr7 Not Cancer Driver No 997-1001 5 5.51e-03 100.0 21 5.26 399 COAD, READ STAD, COAD, READ, HNSC
CELSR1 Q9NYQ6 CELSR1 Cadherin EGF LAG seven-pass G-type receptor 1 chr22 Not Cancer Driver No 1951-1959 9 5.51e-03 100.0 11 2.7 408 - HNSC, KIRC, SKCM, LGG, COAD, BLCA, LUAD, OV
FMN2 Q9NZ56 FMN2 Formin-2 chr1 Not Cancer Driver No 741-754 14 5.51e-03 100.0 19 3.02 629 SKCM HNSC, LGG, UCEC, SKCM, BLCA, LUSC, BRCA, LUAD
MYH14_ENST00000596571 Q7Z406 MYH14 Myosin-14 chr19 Not Cancer Driver No 772-803 32 5.52e-03 9.38 16 5.69 281 - UCEC, READ, KIRC, LUAD, STAD, CESC, LUSC, LGG, BRCA, SKCM
SPATA31D1 Q6ZQQ2 SPATA31D1 Spermatogenesis-associated protein 31D1 chr9 Not Cancer Driver No 988-994 7 5.53e-03 100.0 10 2.43 411 - UCEC, BRCA, STAD, LUAD, LUSC, SKCM, PRAD, LGG
COL1A2 P08123 COL1A2 Collagen alpha-2(I) chain chr7 Not Cancer Driver No 759-798 40 5.54e-03 100.0 25 6.7 373 SKCM KIRC, BLCA, HNSC, PAAD, SKCM, LUAD, READ, LUSC
MGAM_ENST00000475668 O43451 MGAM Maltase-glucoamylase chr7 Not Cancer Driver No 1504-1521 18 5.55e-03 100.0 19 2.66 715 SKCM BLCA, GBM, READ, LUAD, SKCM, HNSC, LUSC
LOR P23490 LORICRIN Loricrin chr1 Not Cancer Driver No 21-31 11 5.56e-03 100.0 3 20.0 15 COAD READ, COAD, STAD, LUAD, SKCM
MUC16 Q8WXI7 MUC16 Mucin-16 chr19 Census Yes 7682-7726 45 5.56e-03 100.0 29 0.69 4204 SKCM PAAD, UCEC, LUAD, PRAD, SARC, HNSC, SKCM, STAD, LUSC, LGG
SPEG Q15772 SPEG Striated muscle preferentially expressed protein kinase chr2 Not Cancer Driver No 710-739 30 5.56e-03 100.0 10 2.44 409 OV SKCM, STAD, LUAD, LUSC, OV
RHBDL1_ENST00000219551 O75783 RHBDL1 Rhomboid-related protein 1 chr16 Not Cancer Driver No 198-245 48 5.57e-03 0.0 15 41.67 36 - KIRC, LUSC, BLCA, GBM, LUAD, SKCM, LIHC, HNSC, UCEC
CDH20_ENST00000538374 Q9HBT6 CDH20 Cadherin-20 chr18 Not Cancer Driver No 671-723 53 5.58e-03 98.15 30 15.38 195 STAD, SKCM HNSC, KIRC, LUSC, COAD, STAD, SKCM, BRCA, UCEC
KIT P10721 KIT Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 812-822 11 5.58e-03 100.0 14 6.19 226 LAML, LUSC LAML, LUSC, CESC, SKCM, HNSC
COL7A1 Q02388 COL7A1 Collagen alpha-1(VII) chain chr3 Not Cancer Driver No 442-451 10 5.58e-03 100.0 10 2.16 462 STAD BRCA, STAD, KIRC, LGG, OV, HNSC, SKCM, LUSC
BHLHE23_ENST00000370346 Q8NDY6 BHLHE23 Class E basic helix-loop-helix protein 23 chr20 Not Cancer Driver No 110-124 15 5.58e-03 0.0 8 50.0 16 STAD, LUAD STAD, UCEC, LUAD, SKCM, HNSC
COTL1 Q14019 COTL1 Coactosin-like protein chr16 Not Cancer Driver No 86-97 12 5.58e-03 0.0 8 47.06 17 LUAD COAD, LGG, BRCA, SKCM, HNSC, LUAD
GNG2_ENST00000615906 P59768 GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 Not Cancer Driver No 53-60 8 5.58e-03 0.0 8 47.06 17 SKCM GBM, BLCA, LUAD, SKCM, UCEC, BRCA
DMBT1_ENST00000619379 Q9UGM3 DMBT1 Deleted in malignant brain tumors 1 protein chr10 Not Cancer Driver No 798-806 9 5.59e-03 0.0 11 2.13 517 LUSC UCEC, LUSC, SKCM, STAD, KIRC, DLBC, BRCA
ARMC4 Q5T2S8 ODAD2 Outer dynein arm-docking complex subunit 2 chr10 Not Cancer Driver No 301-313 13 5.59e-03 30.77 18 6.1 295 STAD, SKCM BRCA, STAD, KIRC, SKCM, HNSC
ZFP36L1 Q07352 ZFP36L1 mRNA decay activator protein ZFP36L1 chr14 Compendium Yes 161-176 16 5.60e-03 0.0 8 14.04 57 BRCA, BLCA LIHC, COAD, BRCA, BLCA, LUAD
CCDC78 A2IDD5 CCDC78 Coiled-coil domain-containing protein 78 chr16 Not Cancer Driver No 92-122 31 5.60e-03 67.74 12 27.91 43 - COT, LUSC, BRCA, LUAD, BLCA, KIRC, SKCM, SARC, CESC
CNTN4_ENST00000418658 Q8IWV2 CNTN4 Contactin-4 chr3 Not Cancer Driver No 163-177 15 5.60e-03 0.0 16 5.26 304 SKCM, LUSC BLCA, COAD, SKCM, GBM, LUSC, UCEC
TRRAP Q9Y4A5 TRRAP Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 722-729 8 5.61e-03 100.0 12 2.16 555 SKCM BLCA, UCEC, LUAD, SKCM
NFKBID Q8NI38 NFKBID NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 292-295 4 5.61e-03 100.0 7 14.58 48 SKCM STAD, SKCM, KIRC, CESC, LUAD, HNSC
ZAN_ENST00000618565 Q9Y493 ZAN Zonadhesin chr7 Not Cancer Driver No 712-720 9 5.61e-03 100.0 10 1.84 543 - LUSC, LUAD, PRAD, KIRC, SKCM, LIHC, LGG
DNMT3A Q9Y6K1 DNMT3A DNA (cytosine-5)-methyltransferase 3A chr2 Census, Compendium Yes 718-729 12 5.62e-03 0.0 12 6.15 195 LAML LUSC, STAD, LUAD, HNSC, UCEC, READ, LAML, LGG, KIRC
MYCBP2_ENST00000357337 O75592 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 chr13 Not Cancer Driver No 3909-3919 11 5.62e-03 100.0 10 1.64 610 - BRCA, HNSC, OV, READ, LUSC, BLCA
ANKHD1 Q8IWZ3 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 60-64 5 5.62e-03 100.0 5 1.71 293 KIRC KIRC, UCEC, SKCM, STAD
ASZ1 Q8WWH4 ASZ1 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 chr7 Not Cancer Driver No 2-33 32 5.63e-03 100.0 19 22.09 86 SKCM SKCM, LGG, STAD, GBM, READ, LUAD, HNSC, LUSC
LRP2 P98164 LRP2 Low-density lipoprotein receptor-related protein 2 chr2 Not Cancer Driver No 1285-1311 27 5.64e-03 100.0 17 1.69 1008 SKCM SKCM, COAD, LUSC, BLCA, READ, OV, STAD, UCEC, CESC
PKDCC Q504Y2 PKDCC Extracellular tyrosine-protein kinase PKDCC chr2 Not Cancer Driver No 263-282 20 5.64e-03 0.0 10 27.03 37 - LUSC, UCEC, LUAD, SKCM, STAD, BRCA, BLCA
PCDHGA2 Q9Y5H1 PCDHGA2 Protocadherin gamma-A2 chr5 Not Cancer Driver No 554-565 12 5.64e-03 8.33 14 4.49 312 LUAD UCEC, CESC, LUSC, COAD, PAAD, STAD, SKCM, LUAD, PRAD
SLC8A1_ENST00000332839 P32418 SLC8A1 Sodium/calcium exchanger 1 chr2 Not Cancer Driver No 360-371 12 5.64e-03 0.0 17 5.57 305 LUAD KIRC, BRCA, UCEC, COAD, SKCM, LUSC, LUAD
EPB41L3 Q9Y2J2 EPB41L3 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1059-1071 13 5.65e-03 100.0 15 5.02 299 STAD UCEC, KIRC, LUSC, STAD, LUAD, CESC, BLCA, OV
TNXB_ENST00000375244 P22105 TNXB Tenascin-X chr6 Not Cancer Driver No 3816-3827 12 5.65e-03 100.0 11 1.65 666 - PRAD, OV, SKCM, COAD, UCEC, STAD, CESC
OR4M2 Q8NGB6 OR4M2 Olfactory receptor 4M2 chr15 Not Cancer Driver No 150-153 4 5.65e-03 0.0 13 5.83 223 SKCM HNSC, UCEC, LUSC, LUAD, SKCM
THSD7B Q9C0I4 THSD7B Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1111-1114 4 5.67e-03 50.0 10 1.52 659 SKCM LUSC, KIRC, SKCM
THSD7B Q9C0I4 THSD7B Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1176-1178 3 5.67e-03 0.0 12 1.82 659 SKCM SKCM, LUAD
RCOR2 Q8IZ40 RCOR2 REST corepressor 2 chr11 Not Cancer Driver No 214-218 5 5.67e-03 100.0 7 12.07 58 BLCA BLCA, OV, SKCM, LIHC, COAD
TES Q9UGI8 TES Testin chr7 Not Cancer Driver No 31-33 3 5.67e-03 0.0 13 23.21 56 READ, COAD READ, UCEC, COAD
NEU3_ENST00000531509 Q9UQ49-2 NEU3 Isoform 2 of Sialidase-3 chr11 Not Cancer Driver No 112-146 35 5.67e-03 100.0 16 27.59 58 SKCM OV, UCEC, BLCA, LUAD, GBM, SKCM
DNAH6 Q9C0G6 DNAH6 Dynein axonemal heavy chain 6 chr2 Not Cancer Driver No 416-462 47 5.68e-03 100.0 15 4.66 322 - HNSC, BRCA, UCEC, LUAD, SKCM, BLCA, LUSC, LIHC, COAD
MXRA5 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 chrX Not Cancer Driver No 2662-2668 7 5.68e-03 100.0 10 1.3 767 LUAD LUAD, LGG, COAD, SKCM, BRCA, PRAD
AHNAK Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK chr11 Not Cancer Driver No 2700-2711 12 5.69e-03 100.0 10 1.24 808 OV BRCA, LUAD, OV, STAD, SKCM, HNSC, LIHC
ABCA13 Q86UQ4 ABCA13 ATP-binding cassette sub-family A member 13 chr7 Not Cancer Driver No 3408-3418 11 5.70e-03 100.0 11 1.16 945 UCEC SKCM, PRAD, UCEC, HNSC, BRCA, LGG
ABCA13 Q86UQ4 ABCA13 ATP-binding cassette sub-family A member 13 chr7 Not Cancer Driver No 4276-4286 11 5.70e-03 100.0 10 1.06 945 - READ, COAD, LIHC, BRCA, UCEC, PRAD, SKCM
WNT8B Q93098 WNT8B Protein Wnt-8b chr10 Not Cancer Driver No 76-79 4 5.72e-03 75.0 8 16.0 50 SKCM KIRC, LIHC, UCEC, LUAD, SKCM
RYR1 P21817 RYR1 Ryanodine receptor 1 chr19 Not Cancer Driver No 2570-2578 9 5.73e-03 100.0 11 1.09 1011 UCEC, SKCM UCEC, SKCM, LUSC, BRCA
RYR3 Q15413 RYR3 Ryanodine receptor 3 chr15 Not Cancer Driver No 3390-3398 9 5.73e-03 100.0 11 1.01 1091 SKCM UCEC, SKCM, PRAD, CESC
LFNG Q8NES3 LFNG Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 Not Cancer Driver No 218-240 23 5.74e-03 0.0 11 29.73 37 COAD THCA, COAD, PRAD, UCEC, BRCA, LIHC, SKCM
MUC4 Q99102 MUC4 Mucin-4 chr3 Census Yes 3440-3446 7 5.74e-03 100.0 10 0.97 1030 - LUAD, KIRC, LIHC, BRCA, UCEC, CESC
NT5C1B Q96P26 NT5C1B Cytosolic 5'-nucleotidase 1B chr2 Not Cancer Driver No 271-277 7 5.74e-03 100.0 7 5.07 138 STAD, HNSC SKCM, STAD, OV, HNSC
OBSCN_ENST00000422127 Q5VST9 OBSCN Obscurin chr1 Not Cancer Driver No 5962-5972 11 5.75e-03 100.0 10 0.8 1252 - OV, LGG, UCEC, STAD, BRCA, KIRC
GRID2 O43424 GRID2 Glutamate receptor ionotropic, delta-2 chr4 Not Cancer Driver No 708-719 12 5.76e-03 0.0 17 4.82 353 SKCM LUSC, LGG, BLCA, LUAD, SKCM, STAD, PRAD, COAD
CDH11 P55287 CDH11 Cadherin-11 chr16 Census, Compendium Yes 42-50 9 5.76e-03 100.0 14 5.26 266 LUAD, LUSC COAD, LUAD, LIHC, LUSC, STAD, BRCA
FLG P20930 FLG Filaggrin chr1 Not Cancer Driver No 2183-2194 12 5.76e-03 100.0 19 1.12 1696 - SKCM, STAD, UCEC, READ, LUAD, BLCA, LUSC, CESC
RYR2 Q92736 RYR2 Ryanodine receptor 2 chr1 Not Cancer Driver No 4057-4071 15 5.76e-03 100.0 16 0.94 1709 LUAD, COAD READ, LUAD, COAD, PRAD, GBM, BLCA, CESC, HNSC, LUSC
RIMS1 Q86UR5 RIMS1 Regulating synaptic membrane exocytosis protein 1 chr6 Not Cancer Driver No 952-968 17 5.76e-03 100.0 16 3.97 403 SKCM LUSC, BLCA, LGG, SKCM, PRAD, LUAD, LIHC, LAML, STAD
E2F1 Q01094 E2F1 Transcription factor E2F1 chr20 Not Cancer Driver No 165-168 4 5.77e-03 0.0 9 18.37 49 UCEC, BRCA LUAD, UCEC, BRCA
NXF2B Q9GZY0 NXF2B Nuclear RNA export factor 2 chrX Not Cancer Driver No 614-621 8 5.77e-03 0.0 7 13.21 53 UCEC UCEC, LUAD, SKCM, BLCA, COAD
TFPI2 P48307 TFPI2 Tissue factor pathway inhibitor 2 chr7 Not Cancer Driver No 222-222 1 5.77e-03 100.0 11 20.37 54 BLCA READ, CESC, BLCA
NXPE2 Q96DL1 NXPE2 NXPE family member 2 chr11 Not Cancer Driver No 65-127 63 5.77e-03 20.0 19 31.15 61 LUSC KIRC, LUAD, LUSC, UCEC, BLCA, SKCM, BRCA, HNSC
WDR73 Q6P4I2 WDR73 WD repeat-containing protein 73 chr15 Not Cancer Driver No 315-320 6 5.79e-03 100.0 3 9.09 33 READ KIRC, BRCA, COAD, READ
FRY Q5TBA9 FRY Protein furry homolog chr13 Not Cancer Driver No 2648-2679 32 5.80e-03 100.0 15 3.21 467 SKCM STAD, KIRC, SKCM, SARC, HNSC, BLCA, LUSC, LUAD
C1QL2 Q7Z5L3 C1QL2 Complement C1q-like protein 2 chr2 Not Cancer Driver No 210-221 12 5.80e-03 0.0 9 27.27 33 - READ, SKCM, CESC, PRAD, GBM, KIRC, STAD
PDPN_ENST00000621990 Q86YL7 PDPN Podoplanin chr1 Not Cancer Driver No 87-92 6 5.80e-03 100.0 10 26.32 38 SKCM SKCM, STAD, KIRC, UCEC, LUAD, OV
HDAC9_ENST00000432645 Q9UKV0 HDAC9 Histone deacetylase 9 chr7 Not Cancer Driver No 521-531 11 5.81e-03 100.0 12 4.2 286 SKCM, LUAD STAD, SKCM, LUAD, LIHC, LUSC, BLCA
UNC13A Q9UPW8 UNC13A Protein unc-13 homolog A chr19 Not Cancer Driver No 1126-1137 12 5.82e-03 0.0 19 6.23 305 SKCM KIRC, STAD, SKCM, SARC, PRAD, LUSC, LUAD
USP29_ENST00000598197 Q9HBJ7 USP29 Ubiquitin carboxyl-terminal hydrolase 29 chr19 Not Cancer Driver No 282-291 10 5.82e-03 30.0 12 4.11 292 SKCM LUAD, SKCM, READ, HNSC, LUSC, BRCA
PLXND1 Q9Y4D7 PLXND1 Plexin-D1 chr3 Not Cancer Driver No 1023-1082 60 5.83e-03 3.33 22 8.63 255 LUAD STAD, SARC, SKCM, UCEC, READ, LUAD, BLCA, COAD
NPAP1 Q9NZP6 NPAP1 Nuclear pore-associated protein 1 chr15 Not Cancer Driver No 478-491 14 5.83e-03 100.0 12 2.11 570 UCEC COAD, BLCA, SKCM, LUSC, LUAD, HNSC, READ, UCEC
CPLANE1 Q9H799 CPLANE1 Ciliogenesis and planar polarity effector 1 chr5 Not Cancer Driver No 1247-1277 31 5.83e-03 100.0 16 4.8 333 SKCM STAD, READ, LUSC, SKCM, BLCA, BRCA, PAAD, COAD
ZNF587 Q96SQ5 ZNF587 Zinc finger protein 587 chr19 Not Cancer Driver No 161-198 38 5.84e-03 100.0 15 18.07 83 BRCA HNSC, LUSC, BLCA, KIRC, UCEC, SKCM, COAD, STAD, BRCA
ARHGAP31 Q2M1Z3 ARHGAP31 Rho GTPase-activating protein 31 chr3 Not Cancer Driver No 407-449 43 5.85e-03 100.0 23 8.42 273 - LUAD, LUSC, UCEC, GBM, COAD, STAD, CESC, READ, BRCA, SKCM
AGO1 Q9UL18 AGO1 Protein argonaute-1 chr1 Not Cancer Driver No 473-532 60 5.85e-03 0.0 20 15.87 126 - COAD, SARC, LUSC, SKCM, READ, LUAD, UCEC, STAD, KIRC, CESC, HNSC, BLCA, BRCA
SPDYC Q5MJ68 SPDYC Speedy protein C chr11 Not Cancer Driver No 98-100 3 5.87e-03 0.0 7 14.0 50 BLCA UCEC, BLCA, LGG, COAD, LUAD, GBM
TPSD1 Q9BZJ3 TPSD1 Tryptase delta chr16 Not Cancer Driver No 143-144 2 5.87e-03 0.0 8 14.04 57 KIRC KIRC
ABCA12 Q86UK0 ABCA12 Glucosylceramide transporter ABCA12 chr2 Not Cancer Driver No 404-423 20 5.88e-03 100.0 17 3.26 521 SKCM READ, LIHC, SKCM, LUAD, BLCA, COAD
ACTRT3 Q9BYD9 ACTRT3 Actin-related protein T3 chr3 Not Cancer Driver No 61-85 25 5.88e-03 0.0 11 23.4 47 SKCM UCEC, SKCM, LUSC, LGG, COAD, STAD, LUAD
SIAH2 O43255 SIAH2 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 272-286 15 5.88e-03 0.0 14 29.17 48 STAD OV, LIHC, UCEC, STAD, KIRC, LUSC, LUAD, SKCM
HECTD4 J3KPF0 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 chr12 Not Cancer Driver No 2489-2529 41 5.88e-03 100.0 14 2.99 469 - HNSC, OV, LUSC, KIRC, STAD, SKCM, LUAD
ITGAX_ENST00000268296 P20702 ITGAX Integrin alpha-X chr16 Not Cancer Driver No 500-535 36 5.89e-03 0.0 22 8.87 248 CESC SKCM, LGG, CESC, BLCA, KIRC, LUAD, HNSC, LUSC, OV, STAD
TPRX1 Q8N7U7 TPRX1 Tetra-peptide repeat homeobox protein 1 chr19 Not Cancer Driver No 313-352 40 5.89e-03 100.0 20 26.32 76 OV LUSC, SKCM, SARC, LUAD, LIHC, UCEC, STAD, OV, BLCA
TLN2 Q9Y4G6 TLN2 Talin-2 chr15 Not Cancer Driver No 32-53 22 5.92e-03 36.36 13 3.82 340 LUSC, LUAD STAD, BLCA, HNSC, SKCM, CESC, LUSC, LUAD
PCDH18 Q9HCL0 PCDH18 Protocadherin-18 chr4 Not Cancer Driver No 578-585 8 5.92e-03 0.0 13 3.64 357 LUAD COAD, PAAD, PRAD, STAD, CESC, LUAD, READ, LIHC
C15orf53 Q8NAA6 LINC02694 Putative uncharacterized protein encoded by LINC02694 chr15 Not Cancer Driver No 131-136 6 5.95e-03 100.0 10 23.81 42 LUSC UCEC, LUSC, STAD, LUAD, READ, SKCM
VAX1 Q5SQQ9 VAX1 Ventral anterior homeobox 1 chr10 Not Cancer Driver No 93-104 12 5.95e-03 83.33 11 30.56 36 STAD, LUAD STAD, LIHC, SKCM, LUAD
C6 P13671 C6 Complement component C6 chr5 Not Cancer Driver No 145-150 6 5.95e-03 0.0 13 3.74 348 SKCM SKCM, KIRC, UCEC, LUSC, HNSC, BLCA
MROH2B Q7Z745 MROH2B Maestro heat-like repeat-containing protein family member 2B chr5 Not Cancer Driver No 1288-1299 12 5.96e-03 0.0 15 2.72 552 SKCM SARC, UCEC, LUAD, SKCM, HNSC, PRAD
MYH1 P12882 MYH1 Myosin-1 chr17 Not Cancer Driver No 782-794 13 5.96e-03 0.0 15 2.74 548 SKCM HNSC, GBM, SKCM, STAD, LUSC, COAD
ARMCX6 Q7L4S7 ARMCX6 Protein ARMCX6 chrX Not Cancer Driver No 44-96 53 5.97e-03 100.0 18 48.65 37 UCEC LUSC, STAD, UCEC, LIHC, BRCA, SKCM, BLCA, SARC, KIRC
MYH6 P13533 MYH6 Myosin-6 chr14 Not Cancer Driver No 847-857 11 5.99e-03 100.0 12 3.02 398 SKCM SKCM, READ, BLCA, LUSC, BRCA, HNSC
GNA13 Q14344 GNA13 Guanine nucleotide-binding protein subunit alpha-13 chr17 Compendium Yes 200-200 1 6.00e-03 0.0 7 13.46 52 BLCA BLCA
HNRNPDL O14979 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like chr4 Not Cancer Driver No 92-95 4 6.00e-03 100.0 7 13.73 51 LUSC KIRC, READ, UCEC, LUSC, STAD, HNSC
LEFTY1 O75610 LEFTY1 Left-right determination factor 1 chr1 Not Cancer Driver No 314-317 4 6.00e-03 0.0 7 12.07 58 GBM UCEC, GBM
POU3F2 P20265 POU3F2 POU domain, class 3, transcription factor 2 chr6 Not Cancer Driver No 315-316 2 6.00e-03 0.0 7 13.46 52 LUAD COAD, LUAD
SP2 Q02086 SP2 Transcription factor Sp2 chr17 Not Cancer Driver No 492-497 6 6.00e-03 100.0 7 11.67 60 SKCM, CESC SKCM, STAD, CESC, GBM
SLC49A4 Q96SL1 SLC49A4 Solute carrier family 49 member 4 chr3 Not Cancer Driver No 214-246 33 6.01e-03 18.18 11 23.4 47 CESC LUSC, CESC, SKCM, HNSC, PRAD, BRCA, BLCA
FMN2 Q9NZ56 FMN2 Formin-2 chr1 Not Cancer Driver No 1620-1630 11 6.01e-03 0.0 15 2.38 629 STAD HNSC, LUAD, BRCA, LUSC, STAD
THSD7A Q9UPZ6 THSD7A Thrombospondin type-1 domain-containing protein 7A chr7 Not Cancer Driver No 277-287 11 6.02e-03 100.0 12 2.92 411 LUSC STAD, SKCM, BRCA, CESC, LIHC, LUSC, BLCA, LUAD
CCR9 P51686 CCR9 C-C chemokine receptor type 9 chr3 Not Cancer Driver No 323-326 4 6.04e-03 0.0 7 11.67 60 SKCM OV, KIRC, BRCA, SKCM, STAD
PLCXD2 Q0VAA5 PLCXD2 PI-PLC X domain-containing protein 2 chr3 Not Cancer Driver No 254-285 32 6.04e-03 53.12 17 28.81 59 SKCM LUAD, SKCM, LUSC, LIHC, BRCA, STAD, READ
ZNF816 Q0VGE8 ZNF816 Zinc finger protein 816 chr19 Not Cancer Driver No 164-193 30 6.04e-03 100.0 11 8.73 126 - STAD, CESC, SKCM, LAML, LIHC, BLCA, COAD, LUAD, HNSC, KIRC
CHRFAM7A Q494W8 CHRFAM7A CHRNA7-FAM7A fusion protein chr15 Not Cancer Driver No 205-255 51 6.04e-03 27.45 15 37.5 40 - COAD, LUSC, LUAD, BRCA, LIHC, BLCA, SKCM, STAD
ACSM6_ENST00000394005 Q6P461 ACSM6 Acyl-coenzyme A synthetase ACSM6, mitochondrial chr10 Not Cancer Driver No 141-214 74 6.05e-03 0.0 22 37.93 58 SKCM KIRC, LUSC, LUAD, BRCA, SKCM, BLCA, LIHC, UCEC
BAG1 Q99933 BAG1 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 211-249 39 6.06e-03 35.9 12 38.71 31 GBM OV, GBM, STAD, BRCA
TNFSF9 P41273 TNFSF9 Tumor necrosis factor ligand superfamily member 9 chr19 Not Cancer Driver No 217-251 35 6.06e-03 22.86 13 40.62 32 SKCM, GBM SKCM, LUSC, LUAD, GBM, BRCA
SRBD1 Q8N5C6 SRBD1 S1 RNA-binding domain-containing protein 1 chr2 Not Cancer Driver No 522-579 58 6.07e-03 1.72 16 14.55 110 LUAD LUSC, KIRC, LUAD, LGG, SKCM, STAD, READ, BRCA, UCEC
NCF1 P14598 NCF1 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 112-130 19 6.09e-03 26.32 10 27.03 37 SKCM CESC, HNSC, BRCA, SKCM, BLCA, STAD
PRH2 P02810 PRH2 Salivary acidic proline-rich phosphoprotein 1/2 chr12 Not Cancer Driver No 42-46 5 6.09e-03 100.0 10 26.32 38 UCEC UCEC, PRAD, KIRC, STAD
RIT1_ENST00000368323 Q92963 RIT1 GTP-binding protein Rit1 chr1 Not Cancer Driver No 81-90 10 6.09e-03 0.0 10 29.41 34 LUAD LAML, CESC, SKCM, LUSC, LUAD, BLCA, PRAD
MYH8 P13535 MYH8 Myosin-8 chr17 Not Cancer Driver No 1705-1716 12 6.10e-03 100.0 12 2.41 498 LUSC LUAD, BRCA, STAD, HNSC, SKCM, LUSC, GBM, CESC
ZNF831 Q5JPB2 ZNF831 Zinc finger protein 831 chr20 Not Cancer Driver No 859-868 10 6.10e-03 100.0 13 2.63 495 LUSC, SKCM LUSC, BLCA, SKCM, READ, LUAD
TNIP1_ENST00000522226 Q15025 TNIP1 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 351-381 31 6.10e-03 9.68 14 16.47 85 SKCM STAD, HNSC, BLCA, KIRC, UCEC, GBM, SKCM
ATAD3A Q9NVI7 ATAD3A ATPase family AAA domain-containing protein 3A chr1 Not Cancer Driver No 244-286 43 6.11e-03 83.72 13 19.4 67 - BLCA, UCEC, STAD, COAD, THCA, GBM, CESC, SKCM
FIZ1 Q96SL8 FIZ1 Flt3-interacting zinc finger protein 1 chr19 Not Cancer Driver No 391-394 4 6.11e-03 100.0 13 21.31 61 READ, COAD READ, SKCM, COAD
PSIP1_ENST00000380738 O75475 PSIP1 PC4 and SFRS1-interacting protein chr9 Census, Compendium Yes 402-405 4 6.11e-03 25.0 7 9.33 75 STAD BLCA, LUSC, LUAD, STAD, OV, UCEC
SDAD1 Q9NVU7 SDAD1 Protein SDA1 homolog chr4 Not Cancer Driver No 395-397 3 6.11e-03 0.0 7 10.45 67 BLCA, LUAD KIRC, STAD, BLCA, LUAD
LRP2 P98164 LRP2 Low-density lipoprotein receptor-related protein 2 chr2 Not Cancer Driver No 3877-3895 19 6.12e-03 100.0 15 1.49 1008 - UCEC, CESC, LGG, OV, LUAD, READ, BRCA, GBM, SKCM, LUSC
SBK1 Q52WX2 SBK1 Serine/threonine-protein kinase SBK1 chr16 Not Cancer Driver No 210-235 26 6.13e-03 15.38 12 29.27 41 SKCM HNSC, SKCM, BLCA, LUAD, KIRC, COT, STAD
PLXNA4 Q9HCM2 PLXNA4 Plexin-A4 chr7 Not Cancer Driver No 301-308 8 6.13e-03 0.0 13 2.17 599 - GBM, LUSC, HNSC, UCEC, STAD, LUAD, COAD, SKCM
DPCD Q9BVM2 DPCD Protein DPCD chr10 Not Cancer Driver No 68-99 32 6.14e-03 34.38 11 52.38 21 - HNSC, STAD, LUSC, KIRC, SKCM, BRCA
MYH2_ENST00000397183 Q9UKX2 MYH2 Myosin-2 chr17 Not Cancer Driver No 1381-1389 9 6.14e-03 100.0 12 2.09 574 SKCM OV, SKCM, KIRC, LGG, UCEC, COAD, STAD, LUSC
ANKHD1 Q8IWZ3 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1708-1717 10 6.14e-03 10.0 6 2.05 293 BLCA UCEC, BLCA, SKCM, COAD, LUSC
UNC93B1 Q9H1C4 UNC93B1 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 210-212 3 6.14e-03 33.33 8 14.04 57 SKCM, BLCA BRCA, SKCM, BLCA, LUAD
NPAP1 Q9NZP6 NPAP1 Nuclear pore-associated protein 1 chr15 Not Cancer Driver No 52-57 6 6.15e-03 100.0 14 2.46 570 - GBM, READ, HNSC, UCEC, LUSC, LUAD, LIHC, STAD, SKCM, THCA
COL22A1 Q8NFW1 COL22A1 Collagen alpha-1(XXII) chain chr8 Not Cancer Driver No 1511-1518 8 6.16e-03 100.0 12 2.09 573 LUAD GBM, STAD, LUSC, SARC, SKCM, OV, LUAD
DNM1L_ENST00000549701 O00429 DNM1L Dynamin-1-like protein chr12 Not Cancer Driver No 468-473 6 6.18e-03 0.0 7 10.45 67 OV, LUAD STAD, BLCA, OV, CESC, LUAD
SDK2 Q58EX2 SDK2 Protein sidekick-2 chr17 Not Cancer Driver No 457-508 52 6.18e-03 23.08 20 5.93 337 - CESC, BRCA, HNSC, LUSC, COAD, STAD, KIRC, SKCM, LUAD
DST_ENST00000370788 Q03001-14 DST Isoform 9 of Dystonin chr6 Not Cancer Driver No 5241-5259 19 6.18e-03 100.0 13 1.78 730 SKCM COAD, LUSC, BLCA, PAAD, SKCM, STAD, UCEC
ZFHX4_ENST00000518282 Q86UP3 ZFHX4 Zinc finger homeobox protein 4 chr8 Not Cancer Driver No 2871-2881 11 6.19e-03 100.0 14 1.08 1297 LUAD STAD, LUAD, BRCA, SKCM, UCEC, BLCA, LUSC, COAD
ATAD2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 chr8 Not Cancer Driver No 262-265 4 6.19e-03 100.0 3 1.32 227 READ LUSC, BLCA, STAD, READ
IRS2 Q9Y4H2 IRS2 Insulin receptor substrate 2 chr13 Not Cancer Driver No 1235-1246 12 6.21e-03 100.0 7 9.72 72 SKCM HNSC, LIHC, LUAD, LUSC, SKCM, PRAD
KIAA0391 O15091 PRORP Mitochondrial ribonuclease P catalytic subunit chr14 Not Cancer Driver No 222-226 5 6.21e-03 0.0 7 10.94 64 SKCM, LUAD UCEC, SKCM, COAD, LUAD
NAV3 Q8IVL0 NAV3 Neuron navigator 3 chr12 Not Cancer Driver No 947-955 9 6.21e-03 100.0 13 1.85 704 LUSC HNSC, UCEC, CESC, SKCM, LUSC, LUAD
OR2L8 Q8NGY9 OR2L8 Olfactory receptor 2L8 chr1 Not Cancer Driver No 111-122 12 6.22e-03 0.0 21 13.12 160 - HNSC, COAD, LUSC, GBM, SKCM, STAD, LUAD, KIRC
ANK2 Q01484 ANK2 Ankyrin-2 chr4 Not Cancer Driver No 3644-3653 10 6.22e-03 100.0 12 1.55 774 GBM STAD, GBM, LUAD, KIRC
CACNA1E_ENST00000621551 Q15878 CACNA1E Voltage-dependent R-type calcium channel subunit alpha-1E chr1 Not Cancer Driver No 2083-2089 7 6.23e-03 100.0 13 1.67 779 SKCM SKCM, KIRC, LUAD, COAD, HNSC, LUSC
PCDHB6 Q9Y5E3 PCDHB6 Protocadherin beta-6 chr5 Not Cancer Driver No 526-561 36 6.24e-03 0.0 29 10.62 273 - LUAD, READ, BLCA, PRAD, HNSC, LUSC, THCA, COAD, SKCM, SARC, UCEC, STAD
RRN3 Q9NYV6 RRN3 RNA polymerase I-specific transcription initiation factor RRN3 chr16 Not Cancer Driver No 9-14 6 6.24e-03 100.0 7 10.61 66 KIRC, LUSC KIRC, SARC, LUSC
NFE2L3 Q9Y4A8 NFE2L3 Nuclear factor erythroid 2-related factor 3 chr7 Not Cancer Driver No 287-325 39 6.24e-03 100.0 17 16.19 105 - THCA, BLCA, LUAD, BRCA, CESC, OV, HNSC, LUSC, GBM
GZF1 Q9H116 GZF1 GDNF-inducible zinc finger protein 1 chr20 Not Cancer Driver No 304-314 11 6.25e-03 100.0 0 0.0 95 UCEC READ, UCEC
POLG_ENST00000442287 P54098 POLG DNA polymerase subunit gamma-1 chr15 Census Yes 55-55 1 6.25e-03 100.0 0 0.0 140 COAD, READ COAD, OV, READ
CYP26B1 Q9NR63 CYP26B1 Cytochrome P450 26B1 chr2 Not Cancer Driver No 316-373 58 6.26e-03 13.79 26 23.01 113 LUAD GBM, LGG, LUSC, SKCM, COAD, STAD, READ, BLCA, LUAD, HNSC, BRCA
NPLOC4 Q8TAT6 NPLOC4 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 457-492 36 6.26e-03 0.0 14 17.5 80 - BLCA, PRAD, LIHC, HNSC, BRCA, SKCM, STAD, LUSC
OR10H3_ENST00000305892 O60404 OR10H3 Olfactory receptor 10H3 chr19 Not Cancer Driver No 54-91 38 6.26e-03 0.0 24 35.82 67 - COAD, PRAD, GBM, SKCM, BRCA, UCEC, BLCA, LUAD, LGG, READ, DLBC
SRPK1 Q96SB4 SRPK1 SRSF protein kinase 1 chr6 Not Cancer Driver No 520-554 35 6.26e-03 0.0 14 19.18 73 SKCM COAD, STAD, THCA, LUAD, KIRC, PAAD, SKCM, BRCA
PIAS1_ENST00000249636 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 241-245 5 6.27e-03 80.0 7 8.75 80 UCEC, BRCA UCEC, BRCA, SARC
EIF4ENIF1 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 298-350 53 6.28e-03 81.13 20 17.24 116 - UCEC, PRAD, STAD, LIHC, BLCA, SKCM, LUSC, LUAD
OR2A2 Q6IF42 OR2A2 Olfactory receptor 2A2 chr7 Not Cancer Driver No 263-277 15 6.28e-03 13.33 17 17.89 95 SKCM, LUAD SKCM, HNSC, LUAD, CESC, STAD
TCOF1 Q13428 TCOF1 Treacle protein chr5 Not Cancer Driver No 1119-1176 58 6.29e-03 100.0 14 9.46 148 SKCM, COAD UCEC, SKCM, LUSC, OV, READ, HNSC, COAD
GLT8D2 Q9H1C3 GLT8D2 Glycosyltransferase 8 domain-containing protein 2 chr12 Not Cancer Driver No 178-179 2 6.30e-03 0.0 8 11.11 72 GBM OV, GBM
RANBP9 Q96S59 RANBP9 Ran-binding protein 9 chr6 Not Cancer Driver No 10-10 1 6.30e-03 100.0 7 9.59 73 SKCM PRAD, BLCA, LGG, STAD, SKCM, KIRC
CSMD1 Q96PZ7 CSMD1 CUB and sushi domain-containing protein 1 chr8 Not Cancer Driver No 1070-1076 7 6.32e-03 100.0 15 1.2 1248 SKCM LIHC, SKCM, LUSC
C1QTNF9_ENST00000332018 P0C862 C1QTNF9 Complement C1q and tumor necrosis factor-related protein 9A chr13 Not Cancer Driver No 74-76 3 6.32e-03 100.0 7 9.46 74 SKCM SKCM, KIRC, CESC, LUAD
TTN_ENST00000615779 Q8WZ42 TTN Titin chr2 Not Cancer Driver No 9552-9568 17 6.33e-03 100.0 19 0.24 7986 SKCM HNSC, LIHC, SKCM
WASF1_ENST00000392586 Q92558 WASF1 Wiskott-Aldrich syndrome protein family member 1 chr6 Not Cancer Driver No 231-266 36 6.34e-03 100.0 13 20.31 64 SKCM BRCA, SKCM, BLCA, LUAD, STAD, CESC
USH2A O75445 USH2A Usherin chr1 Not Cancer Driver No 1902-1911 10 6.35e-03 100.0 12 0.79 1517 LUSC, SKCM SARC, BRCA, LUSC, OV, SKCM
SYNE1 Q8NF91 SYNE1 Nesprin-1 chr6 Not Cancer Driver No 162-175 14 6.35e-03 100.0 12 0.7 1711 - READ, LUSC, PRAD, STAD, SKCM, HNSC, BRCA, BLCA, COAD
DNTT P04053 DNTT DNA nucleotidylexotransferase chr10 Not Cancer Driver No 5-48 44 6.35e-03 54.55 18 16.98 106 SKCM READ, KIRC, LUAD, GBM, BRCA, LIHC, LGG, UCEC, SKCM
ZBTB14_ENST00000615385 O43829 ZBTB14 Zinc finger and BTB domain-containing protein 14 chr18 Not Cancer Driver No 82-82 1 6.35e-03 100.0 9 12.5 72 SKCM LUAD, STAD, LUSC, SKCM
ZMYND15_ENST00000433935 Q9H091 ZMYND15 Zinc finger MYND domain-containing protein 15 chr17 Not Cancer Driver No 440-443 4 6.38e-03 50.0 7 7.87 89 SKCM SKCM, UCEC
CLDN19 Q8N6F1 CLDN19 Claudin-19 chr1 Not Cancer Driver No 81-109 29 6.38e-03 0.0 10 35.71 28 - OV, COAD, KIRC, LUSC, SKCM, LGG
NUTF2_ENST00000569436 P61970 NUTF2 Nuclear transport factor 2 chr16 Not Cancer Driver No 20-31 12 6.38e-03 0.0 12 50.0 24 SKCM SKCM, LUAD, BLCA, HNSC, STAD
LHX8 Q68G74 LHX8 LIM/homeobox protein Lhx8 chr1 Not Cancer Driver No 277-293 17 6.40e-03 83.33 15 16.13 93 - BRCA, SKCM, LUAD, CESC, KIRC, LUSC, PAAD, LGG
POMT2 Q9UKY4 POMT2 Protein O-mannosyl-transferase 2 chr14 Not Cancer Driver No 199-241 43 6.41e-03 0.0 14 16.47 85 BRCA LIHC, READ, KIRC, STAD, LUAD, SKCM, UCEC, BRCA
TTN_ENST00000615779 Q8WZ42 TTN Titin chr2 Not Cancer Driver No 6559-6568 10 6.45e-03 100.0 12 0.15 7986 LUSC CESC, LUSC, STAD, UCEC, KIRC, BLCA, HNSC, SKCM
TTN_ENST00000615779 Q8WZ42 TTN Titin chr2 Not Cancer Driver No 7009-7022 14 6.45e-03 100.0 12 0.15 7986 SKCM BLCA, SKCM, COAD, STAD, OV
PRR14L Q5THK1 PRR14L Protein PRR14L chr22 Not Cancer Driver No 1862-1869 8 6.45e-03 100.0 7 6.54 107 UCEC SKCM, KIRC, LUSC, READ, UCEC
PCLO Q9Y6V0 PCLO Protein piccolo chr7 Not Cancer Driver No 4231-4268 38 6.47e-03 100.0 28 1.72 1627 SKCM READ, LUSC, STAD, BLCA, SKCM, LUAD, BRCA
TENT4B Q8NDF8-5 TENT4B Isoform 5 of Terminal nucleotidyltransferase 4B chr16 Not Cancer Driver No 218-255 38 6.47e-03 100.0 14 22.58 62 UCEC STAD, LAML, LUSC, SKCM, COAD, UCEC
TRIM11 Q96F44 TRIM11 E3 ubiquitin-protein ligase TRIM11 chr1 Not Cancer Driver No 324-351 28 6.47e-03 0.0 11 18.97 58 UCEC BRCA, STAD, SKCM, UCEC, HNSC, LUAD, LUSC
ANKRD30BL A7E2S9 ANKRD30BL Putative ankyrin repeat domain-containing protein 30B-like chr2 Not Cancer Driver No 228-232 5 6.47e-03 100.0 9 20.45 44 SKCM SKCM, LUSC, LUAD, HNSC, KIRC
BCL2L11 O43521 BCL2L11 Bcl-2-like protein 11 chr2 Not Cancer Driver No 153-156 4 6.47e-03 0.0 11 26.19 42 UCEC GBM, UCEC, OV, BRCA, HNSC, CESC, STAD
FAM173B Q6P4H8 ATPSCKMT ATP synthase subunit C lysine N-methyltransferase chr5 Not Cancer Driver No 101-106 6 6.47e-03 0.0 9 20.93 43 - SKCM, HNSC, BRCA, LUAD, STAD, LUSC, READ
KLRC3_ENST00000396439 Q07444 KLRC3 NKG2-E type II integral membrane protein chr12 Not Cancer Driver No 175-184 10 6.47e-03 0.0 9 22.5 40 SKCM STAD, PAAD, SKCM, HNSC, UCEC, LUSC
TLX3 O43711 TLX3 T-cell leukemia homeobox protein 3 chr5 Census Yes 7-40 34 6.48e-03 100.0 14 35.0 40 - LUAD, UCEC, BLCA, LIHC, LUSC, STAD, READ, SKCM
FAM161B Q96MY7-2 FAM161B Isoform 2 of Protein FAM161B chr14 Not Cancer Driver No 429-473 45 6.48e-03 100.0 16 19.05 84 - OV, BRCA, STAD, CESC, UCEC, HNSC, LIHC, LUSC, COAD
CACNB4 O00305 CACNB4 Voltage-dependent L-type calcium channel subunit beta-4 chr2 Not Cancer Driver No 217-220 4 6.49e-03 0.0 7 8.54 82 COAD, SKCM CESC, LUAD, READ, COAD, SKCM
RTL1 A6NKG5 RTL1 Retrotransposon-like protein 1 chr14 Not Cancer Driver No 11-55 45 6.51e-03 100.0 21 10.55 199 SKCM LUAD, SKCM, STAD, KIRC, BLCA, LUSC, UCEC
FTCD_ENST00000291670 O95954 FTCD Formimidoyltransferase-cyclodeaminase chr21 Not Cancer Driver No 438-440 3 6.53e-03 0.0 19 19.79 96 READ, COAD LUAD, READ, COAD
EEFSEC P57772 EEFSEC Selenocysteine-specific elongation factor chr3 Not Cancer Driver No 190-223 34 6.54e-03 26.47 20 25.0 80 - LUSC, BLCA, SKCM, LUAD, STAD, KIRC, UCEC
MSL3 Q8N5Y2 MSL3 Male-specific lethal 3 homolog chrX Not Cancer Driver No 352-353 2 6.55e-03 100.0 7 7.87 89 COAD HNSC, COAD, BLCA, LUSC
HGS O14964 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 288-328 41 6.57e-03 100.0 20 17.54 114 - BLCA, CESC, UCEC, STAD, GBM, LIHC, OV, BRCA, SKCM
RFC1 P35251 RFC1 Replication factor C subunit 1 chr4 Not Cancer Driver No 613-667 55 6.57e-03 36.36 20 13.61 147 - SKCM, THCA, GBM, STAD, KIRC, LAML, HNSC, BLCA, BRCA, LIHC
ACSL3 O95573 ACSL3 Fatty acid CoA ligase Acsl3 chr2 Census, Compendium Yes 230-232 3 6.57e-03 0.0 7 7.78 90 COT, UCEC COT, UCEC, STAD
AGBL4 Q5VU57 AGBL4 Cytosolic carboxypeptidase 6 chr1 Not Cancer Driver No 282-311 30 6.57e-03 0.0 15 22.73 66 - LUSC, READ, UCEC, SKCM, COAD, KICH, OV, KIRC, BRCA
CCDC28A Q8IWP9 CCDC28A Coiled-coil domain-containing protein 28A chr6 Not Cancer Driver No 25-38 14 6.57e-03 78.57 12 24.0 50 SKCM READ, SKCM, STAD, BLCA, LUAD
ESRRA_ENST00000000442 P11474 ESRRA Steroid hormone receptor ERR1 chr11 Compendium Yes 215-227 13 6.58e-03 61.54 9 24.32 37 HNSC HNSC, LIHC, BLCA, SKCM, STAD
FBL P22087 FBL rRNA 2'-O-methyltransferase fibrillarin chr19 Not Cancer Driver No 66-74 9 6.58e-03 100.0 10 21.74 46 LUAD PRAD, UCEC, LUAD, LUSC, STAD, BRCA
RNF145_ENST00000519865 Q96MT1 RNF145 RING finger protein 145 chr5 Not Cancer Driver No 141-145 5 6.61e-03 0.0 7 7.45 94 UCEC, GBM UCEC, LUSC, SKCM, GBM
ADGRB2_ENST00000373658 O60241 ADGRB2 Adhesion G protein-coupled receptor B2 chr1 Not Cancer Driver No 1409-1461 53 6.63e-03 100.0 18 8.74 206 - LUAD, STAD, PAAD, COAD, SKCM, BLCA, LUSC
GRIN3B O60391 GRIN3B Glutamate receptor ionotropic, NMDA 3B chr19 Not Cancer Driver No 404-404 1 6.64e-03 100.0 16 14.95 107 READ, COAD READ, COAD
DISP1 Q96F81 DISP1 Protein dispatched homolog 1 chr1 Not Cancer Driver No 1010-1061 52 6.67e-03 0.0 21 9.77 215 - UCEC, READ, BRCA, COAD, BLCA, SKCM, STAD, LUSC, LUAD
FGF6 P10767 FGF6 Fibroblast growth factor 6 chr12 Not Cancer Driver No 54-64 11 6.67e-03 100.0 18 25.0 72 - LUSC, COAD, OV, PAAD, BRCA, LUAD, HNSC, SKCM
CENPI_ENST00000423383 Q92674 CENPI Centromere protein I chrX Not Cancer Driver No 682-686 5 6.68e-03 0.0 7 6.54 107 LUAD UCEC, OV, SKCM, LUAD
FAM78A Q5JUQ0 FAM78A Protein FAM78A chr9 Not Cancer Driver No 160-192 33 6.68e-03 0.0 15 30.61 49 - GBM, KIRC, STAD, OV, THCA, HNSC, SKCM, COAD, LIHC, BRCA, UCEC
BORCS5 Q969J3 BORCS5 BLOC-1-related complex subunit 5 chr12 Not Cancer Driver No 38-70 33 6.68e-03 51.52 13 54.17 24 BLCA, STAD BLCA, OV, STAD, HNSC, LUAD, THCA
CRCT1 Q9UGL9 CRCT1 Cysteine-rich C-terminal protein 1 chr1 Not Cancer Driver No 14-47 34 6.68e-03 94.44 15 71.43 21 SKCM LGG, LUSC, STAD, UCEC, COAD, READ, HNSC, BLCA, SKCM
GRB10_ENST00000401949 Q13322 GRB10 Growth factor receptor-bound protein 10 chr7 Not Cancer Driver No 501-504 4 6.69e-03 0.0 7 7.45 94 LUAD LUAD, LUSC, SARC, SKCM, UCEC
MINDY2 Q8NBR6 MINDY2 Ubiquitin carboxyl-terminal hydrolase MINDY-2 chr15 Not Cancer Driver No 588-605 18 6.69e-03 100.0 11 20.75 53 SKCM COAD, HNSC, BLCA, READ, KIRC, LUSC, SKCM
KCNK7 Q9Y2U2 KCNK7 Potassium channel subfamily K member 7 chr11 Not Cancer Driver No 263-297 35 6.75e-03 77.14 12 38.71 31 LUAD, SKCM LUAD, PRAD, BLCA, STAD, BRCA, SARC, SKCM, LUSC
RAX Q9Y2V3 RAX Retinal homeobox protein Rx chr18 Not Cancer Driver No 100-137 38 6.75e-03 100.0 14 46.67 30 LUSC BRCA, SKCM, UCEC, LUSC, HNSC, STAD
ZNF133_ENST00000622607 P52736 ZNF133 Zinc finger protein 133 chr20 Not Cancer Driver No 473-473 1 6.76e-03 0.0 7 7.0 100 OV BRCA, OV
ERVW-1_ENST00000603053 Q9UQF0 ERVW-1 Syncytin-1 chr7 Not Cancer Driver No 155-183 29 6.77e-03 100.0 13 21.31 61 BLCA, SKCM BLCA, LIHC, OV, LUSC, CESC, SKCM
ALX4 Q9H161 ALX4 Homeobox protein aristaless-like 4 chr11 Not Cancer Driver No 102-102 1 6.77e-03 100.0 14 13.08 107 COAD, READ COAD, READ
IP6K3 Q96PC2 IP6K3 Inositol hexakisphosphate kinase 3 chr6 Not Cancer Driver No 182-236 55 6.78e-03 9.09 24 28.24 85 SKCM COAD, UCEC, STAD, BLCA, READ, KIRC, SKCM, LUAD, CESC, BRCA, LUSC, HNSC
ASAH2 Q9NR71 ASAH2 Neutral ceramidase chr10 Not Cancer Driver No 338-372 35 6.79e-03 0.0 14 19.44 72 SKCM COAD, CESC, LUAD, SKCM, UCEC, BLCA, KIRC
SHPRH Q149N8 SHPRH E3 ubiquitin-protein ligase SHPRH chr6 Not Cancer Driver No 913-965 53 6.80e-03 15.09 19 8.37 227 OV STAD, LUSC, LUAD, SARC, SKCM, OV, BLCA
MTREX P42285 MTREX Exosome RNA helicase MTR4 chr5 Not Cancer Driver No 500-505 6 6.80e-03 0.0 7 5.98 117 BLCA, LUAD STAD, BLCA, LUAD
SEC24B_ENST00000265175 O95487 SEC24B Protein transport protein Sec24B chr4 Not Cancer Driver No 430-470 41 6.81e-03 100.0 11 8.09 136 READ READ, LUAD, OV, UCEC, KIRC, BLCA, LUSC, STAD, COAD
RASA3 Q14644 RASA3 Ras GTPase-activating protein 3 chr13 Not Cancer Driver No 725-759 35 6.81e-03 20.0 17 14.41 118 SKCM LUSC, BLCA, STAD, LUAD, HNSC, UCEC, OV, LIHC, CESC, SKCM
LRIF1 Q5T3J3 LRIF1 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 21-23 3 6.84e-03 100.0 7 5.98 117 BRCA, BLCA THCA, BRCA, BLCA, CESC
CA4 P22748 CA4 Carbonic anhydrase 4 chr17 Not Cancer Driver No 212-227 16 6.86e-03 0.0 12 21.82 55 OV LIHC, LUSC, UCEC, BRCA, OV, CESC, SKCM
GSTM5 P46439 GSTM5 Glutathione S-transferase Mu 5 chr1 Not Cancer Driver No 160-168 9 6.86e-03 0.0 11 18.64 59 GBM BLCA, GBM, LUSC
SPATA31A1 Q5TZJ5 SPATA31A1 Spermatogenesis-associated protein 31A1 chr9 Not Cancer Driver No 1088-1121 34 6.86e-03 100.0 6 46.15 13 SKCM, LUAD SKCM, BLCA, BRCA, LUAD
CFAP74 Q9C0B2 CFAP74 Cilia- and flagella-associated protein 74 chr1 Not Cancer Driver No 194-202 9 6.87e-03 55.56 7 6.25 112 SKCM, UCEC, COAD STAD, SKCM, UCEC, COAD
LCMT2 O60294 LCMT2 tRNA wybutosine-synthesizing protein 4 chr15 Not Cancer Driver No 82-84 3 6.87e-03 0.0 7 6.73 104 BLCA, CESC LUAD, BLCA, CESC, HNSC
TRMT61B Q9BVS5 TRMT61B tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 239-284 46 6.87e-03 0.0 14 29.17 48 SKCM LUAD, SKCM, STAD, LUSC, CESC
FAM91A1 Q658Y4 FAM91A1 Protein FAM91A1 chr8 Not Cancer Driver No 377-379 3 6.88e-03 0.0 9 7.44 121 STAD LUAD, UCEC, READ, COAD, STAD, PRAD
ZNF215_ENST00000414517 Q9UL58 ZNF215 Zinc finger protein 215 chr11 Not Cancer Driver No 419-434 16 6.88e-03 31.25 6 6.06 99 BLCA BLCA, HNSC, LGG, STAD, COAD, SARC
B4GALNT4 Q76KP1 B4GALNT4 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 chr11 Not Cancer Driver No 849-852 4 6.89e-03 0.0 7 6.14 114 LUAD STAD, READ, LUAD, HNSC, BLCA, KIRC
RRP15 Q9Y3B9 RRP15 RRP15-like protein chr1 Not Cancer Driver No 2-9 8 6.89e-03 100.0 9 18.0 50 LUSC LUAD, READ, KIRC, OV, LUSC, SKCM
GPR50 Q13585 GPR50 Melatonin-related receptor chrX Not Cancer Driver No 327-366 40 6.90e-03 40.0 28 15.91 176 - READ, SARC, COAD, UCEC, SKCM, BRCA, STAD, LUSC, OV, HNSC, CESC, LUAD, BLCA
XPO1_ENST00000406957 O14980 XPO1 Exportin-1 chr2 Census, Compendium Yes 571-575 5 6.90e-03 0.0 10 7.14 140 BRCA, DLBC, UCEC BRCA, DLBC, UCEC
ZCCHC14 Q8WYQ9 ZCCHC14 Zinc finger CCHC domain-containing protein 14 chr16 Not Cancer Driver No 378-382 5 6.90e-03 100.0 7 5.65 124 BLCA BLCA, GBM, PRAD
DOK5 Q9P104 DOK5 Docking protein 5 chr20 Not Cancer Driver No 178-192 15 6.90e-03 0.0 13 14.44 90 - READ, LUAD, UCEC, STAD, CESC, BLCA, BRCA
EMC10 Q5UCC4 EMC10 ER membrane protein complex subunit 10 chr19 Not Cancer Driver No 176-204 29 6.91e-03 0.0 11 42.31 26 CESC BRCA, PRAD, COAD, SKCM, UCEC, CESC, LIHC
PKD2 Q13563 PKD2 Polycystin-2 chr4 Not Cancer Driver No 484-486 3 6.91e-03 0.0 7 6.19 113 LAML, KIRC LAML, KIRC, OV
WDR35 Q9P2L0 WDR35 WD repeat-containing protein 35 chr2 Not Cancer Driver No 467-472 6 6.91e-03 100.0 9 6.52 138 - OV, LUAD, KIRC, READ, LAML, LUSC, COAD
PRB3_ENST00000381842 Q04118 PRB3 Basic salivary proline-rich protein 3 chr12 Not Cancer Driver No 200-200 1 6.92e-03 100.0 9 8.33 108 UCEC, SKCM, BRCA LUSC, UCEC, SKCM, BRCA
PACS1 Q6VY07 PACS1 Phosphofurin acidic cluster sorting protein 1 chr11 Not Cancer Driver No 269-272 4 6.93e-03 100.0 9 7.38 122 SKCM, UCEC SKCM, KIRC, UCEC, READ
PLA2G4D Q86XP0 PLA2G4D Cytosolic phospholipase A2 delta chr15 Not Cancer Driver No 434-434 1 6.93e-03 0.0 16 12.7 126 COAD, READ COAD, READ, BLCA
TMTC1 Q8IUR5 TMTC1 Protein O-mannosyl-transferase TMTC1 chr12 Not Cancer Driver No 325-365 41 6.93e-03 0.0 23 12.85 179 LUAD KIRC, STAD, SKCM, GBM, BLCA, BRCA, LGG, LUAD
AP3B1 O00203 AP3B1 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 31-34 4 6.94e-03 100.0 7 5.51 127 LUSC, CESC BLCA, LUSC, HNSC, CESC
TENT4A_ENST00000230859 Q5XG87 TENT4A Terminal nucleotidyltransferase 4A chr5 Not Cancer Driver No 256-310 55 6.94e-03 0.0 21 20.59 102 - PRAD, BLCA, LGG, LUSC, LUAD, KIRC, UCEC, LIHC, DLBC, BRCA, SKCM, HNSC
HIST1H2BC P62807 H2BC10 Histone H2B type 1-C/E/F/G/I chr6 Not Cancer Driver No 72-77 6 6.95e-03 0.0 11 20.75 53 LUSC OV, BRCA, LUSC, BLCA, DLBC, CESC
CDHR5 Q9HBB8 CDHR5 Cadherin-related family member 5 chr11 Not Cancer Driver No 823-826 4 6.95e-03 100.0 8 7.02 114 CESC, BLCA CESC, SKCM, BLCA, LUAD
GCK_ENST00000403799 P35557 GCK Hexokinase-4 chr7 Not Cancer Driver No 187-222 36 6.95e-03 0.0 17 19.32 88 SKCM CESC, LUSC, BRCA, KIRC, STAD, READ, COAD, SKCM, UCEC
TRPC3_ENST00000264811 Q13507 TRPC3 Short transient receptor potential channel 3 chr4 Not Cancer Driver No 90-138 49 6.95e-03 36.73 25 12.63 198 STAD BRCA, LIHC, STAD, SARC, LUSC, UCEC, COAD, LGG, LUAD, THCA, OV, SKCM
CRISPLD1 Q9H336 CRISPLD1 Cysteine-rich secretory protein LCCL domain-containing 1 chr8 Not Cancer Driver No 5-6 2 6.96e-03 100.0 7 6.09 115 COAD STAD, READ, BRCA, BLCA, COAD, LUSC
GFM2_ENST00000509430 Q969S9 GFM2 Ribosome-releasing factor 2, mitochondrial chr5 Not Cancer Driver No 507-543 37 6.96e-03 8.11 13 17.11 76 - BLCA, BRCA, LUSC, UCEC, SKCM, LIHC, STAD, GBM
RELCH Q9P260 RELCH RAB11-binding protein RELCH chr18 Not Cancer Driver No 579-579 1 6.96e-03 0.0 7 6.14 114 KIRC, LUAD UCEC, PRAD, KIRC, LUAD
SSH1 Q8WYL5 SSH1 Protein phosphatase Slingshot homolog 1 chr12 Not Cancer Driver No 397-401 5 6.96e-03 0.0 7 5.43 129 OV, UCEC LUAD, PRAD, OV, READ, UCEC
HAVCR1_ENST00000339252 Q96D42 HAVCR1 Hepatitis A virus cellular receptor 1 chr5 Not Cancer Driver No 197-208 12 6.96e-03 100.0 9 9.47 95 SKCM PRAD, SKCM, LUAD, HNSC, COAD, OV
CLVS1 Q8IUQ0 CLVS1 Clavesin-1 chr8 Not Cancer Driver No 165-179 15 6.97e-03 0.0 17 14.05 121 SKCM LUSC, SKCM, GBM, UCEC, LUAD
HECW1 Q76N89 HECW1 E3 ubiquitin-protein ligase HECW1 chr7 Not Cancer Driver No 649-686 38 6.98e-03 100.0 24 5.65 425 - STAD, LUAD, UCEC, COAD, BLCA, LIHC, HNSC, GBM, SKCM, LUSC, OV, READ
MAP1S Q66K74 MAP1S Microtubule-associated protein 1S chr19 Not Cancer Driver No 410-411 2 6.98e-03 0.0 13 9.63 135 READ, COAD READ, COAD, DLBC
MIDN Q504T8 MIDN Midnolin chr19 Not Cancer Driver No 410-417 8 6.98e-03 87.5 9 20.93 43 STAD HNSC, SKCM, KIRC, PAAD, LUSC, LIHC, STAD
IGSF5 Q9NSI5 IGSF5 Immunoglobulin superfamily member 5 chr21 Not Cancer Driver No 286-300 15 6.99e-03 100.0 12 14.29 84 COAD LUAD, SKCM, STAD, COAD, LUSC, UCEC
ARHGEF1_ENST00000354532 Q92888 ARHGEF1 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 124-127 4 7.00e-03 0.0 8 6.3 127 UCEC OV, UCEC, BLCA, SKCM, KIRC
CCR3_ENST00000357422 P51677 CCR3 C-C chemokine receptor type 3 chr3 Not Cancer Driver No 302-316 15 7.01e-03 0.0 16 19.05 84 - LGG, LIHC, READ, COAD, SKCM, OV, LUSC, STAD
DHRS7C A6NNS2 DHRS7C Dehydrogenase/reductase SDR family member 7C chr17 Not Cancer Driver No 181-193 13 7.01e-03 0.0 15 18.07 83 SKCM UCEC, LUSC, READ, BRCA, SKCM, HNSC
ZPLD1_ENST00000491959 Q8TCW7 ZPLD1 Zona pellucida-like domain-containing protein 1 chr3 Not Cancer Driver No 232-269 38 7.02e-03 0.0 24 20.69 116 SKCM UCEC, SKCM, LGG, OV, LUAD, LUSC, BRCA, HNSC, CESC
KLF4 O43474-1 KLF4 Isoform 2 of Krueppel-like factor 4 chr9 Census, Compendium Yes 402-418 17 7.03e-03 100.0 13 22.41 58 BRCA GBM, THCA, PAAD, COAD, STAD, LUAD, PRAD, BRCA, BLCA
SOX6_ENST00000528429 P35712 SOX6 Transcription factor SOX-6 chr11 Not Cancer Driver No 612-614 3 7.04e-03 100.0 9 6.87 131 OV, KIRC OV, KIRC, COAD, UCEC, BRCA
HIST1H1E P10412 H1-4 Histone H1.4 chr6 Not Cancer Driver No 23-27 5 7.06e-03 100.0 6 9.09 66 LUAD LUAD, THCA, BLCA, STAD, UCEC, BRCA, COAD
RARG P13631 RARG Retinoic acid receptor gamma chr12 Not Cancer Driver No 285-341 57 7.06e-03 0.0 24 28.92 83 BLCA LIHC, UCEC, OV, CESC, BRCA, BLCA, HNSC
HEYL Q9NQ87 HEYL Hairy/enhancer-of-split related with YRPW motif-like protein chr1 Not Cancer Driver No 135-169 35 7.07e-03 33.33 14 31.11 45 SKCM CESC, STAD, UCEC, HNSC, THCA, LUSC, COAD, SKCM
RUBCN Q92622 RUBCN Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 Not Cancer Driver No 649-652 4 7.08e-03 75.0 7 4.64 151 BLCA BLCA, HNSC
ZC3H7B Q9UGR2 ZC3H7B Zinc finger CCCH domain-containing protein 7B chr22 Not Cancer Driver No 308-311 4 7.08e-03 100.0 8 6.02 133 GBM GBM
ZNF585B Q52M93 ZNF585B Zinc finger protein 585B chr19 Not Cancer Driver No 102-103 2 7.09e-03 100.0 7 4.35 161 HNSC, LUAD STAD, LUSC, HNSC, LUAD
ST6GAL2_ENST00000361686 Q96JF0 ST6GAL2 Beta-galactoside alpha-2,6-sialyltransferase 2 chr2 Not Cancer Driver No 219-223 5 7.09e-03 0.0 6 2.65 226 BLCA BLCA, PRAD, STAD, COAD, SKCM
ANO7 Q6IWH7 ANO7 Anoctamin-7 chr2 Not Cancer Driver No 408-411 4 7.09e-03 0.0 8 5.44 147 LUAD, GBM LUAD, SARC, PRAD, STAD, GBM
FZD10 Q9ULW2 FZD10 Frizzled-10 chr12 Not Cancer Driver No 392-393 2 7.09e-03 0.0 7 4.73 148 GBM GBM, KIRC, COAD, PAAD, STAD, LUSC
TGFA_ENST00000295400 P01135 TGFA Protransforming growth factor alpha chr2 Not Cancer Driver No 19-29 11 7.10e-03 41.67 9 42.86 21 GBM GBM, LIHC, KIRC, BRCA, STAD, LUSC
ANKRD44 Q8N8A2 ANKRD44 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B chr2 Not Cancer Driver No 587-624 38 7.11e-03 5.26 17 12.5 136 LUAD READ, COAD, OV, STAD, HNSC, LUSC, LIHC, SKCM, DLBC, LUAD
C2CD2 Q9Y426 C2CD2 C2 domain-containing protein 2 chr21 Not Cancer Driver No 413-446 34 7.11e-03 82.86 13 15.66 83 SKCM BLCA, SKCM, LUSC, READ, UCEC, HNSC, GBM
CBFA2T3 O75081 CBFA2T3 Protein CBFA2T3 chr16 Census, Compendium Yes 338-368 31 7.11e-03 100.0 14 16.87 83 - SKCM, HNSC, UCEC, READ, STAD, LUAD, LUSC, BLCA
CBLN4 Q9NTU7 CBLN4 Cerebellin-4 chr20 Not Cancer Driver No 57-96 40 7.11e-03 30.0 28 45.16 62 - UCEC, BLCA, READ, COAD, STAD, LGG, LUAD, HNSC, CESC, SKCM, BRCA, OV
WDR87_ENST00000303868 Q6ZQQ6 WDR87 WD repeat-containing protein 87 chr19 Not Cancer Driver No 95-102 8 7.13e-03 100.0 8 3.33 240 UCEC, KIRC UCEC, COAD, KIRC
WDR87_ENST00000303868 Q6ZQQ6 WDR87 WD repeat-containing protein 87 chr19 Not Cancer Driver No 2264-2269 6 7.13e-03 100.0 8 3.33 240 COAD, READ COAD, READ
MPP7 Q5T2T1 MPP7 MAGUK p55 subfamily member 7 chr10 Not Cancer Driver No 120-141 22 7.13e-03 77.27 18 13.53 133 SKCM LUSC, GBM, BRCA, SKCM, UCEC, CESC, DLBC
SLFN11_ENST00000308377 Q7Z7L1 SLFN11 Schlafen family member 11 chr17 Not Cancer Driver No 207-208 2 7.13e-03 0.0 8 4.47 179 SKCM STAD, SKCM
AGPAT2_ENST00000538402 O15120 AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta chr9 Not Cancer Driver No 17-22 6 7.14e-03 0.0 1 4.0 25 COAD READ, LGG, COAD, REO
ARHGEF17 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 chr11 Not Cancer Driver No 226-235 10 7.14e-03 100.0 2 0.84 238 UCEC UCEC, OV, BRCA, LIHC
EBF2 Q9HAK2 EBF2 Transcription factor COE2 chr8 Not Cancer Driver No 444-444 1 7.15e-03 100.0 7 4.43 158 SKCM UCEC, SKCM
EXOC2 Q96KP1 EXOC2 Exocyst complex component 2 chr6 Not Cancer Driver No 419-462 44 7.16e-03 59.09 16 15.09 106 - SKCM, LUAD, LUSC, OV, UCEC, BLCA, STAD, BRCA
ITGAV P06756 ITGAV Integrin alpha-V chr2 Census Yes 23-23 1 7.16e-03 100.0 7 4.58 153 GBM HNSC, GBM
ANKRD30A_ENST00000611781 Q9BXX3 ANKRD30A Ankyrin repeat domain-containing protein 30A chr10 Not Cancer Driver No 375-399 25 7.17e-03 100.0 23 4.2 547 SKCM OV, LUAD, LGG, COAD, BLCA, CESC, SKCM, UCEC
MUC12_ENST00000379442 Q9UKN1 MUC12 Mucin-12 chr7 Not Cancer Driver No 2770-2777 8 7.19e-03 100.0 6 4.2 143 BRCA BRCA, CESC
TONSL Q96HA7 TONSL Tonsoku-like protein chr8 Not Cancer Driver No 159-163 5 7.19e-03 0.0 8 4.94 162 OV LUSC, OV, LIHC, READ
TONSL Q96HA7 TONSL Tonsoku-like protein chr8 Not Cancer Driver No 714-715 2 7.19e-03 100.0 12 7.41 162 READ STAD, READ, SKCM, COAD
PCDHGB5 Q9Y5G0 PCDHGB5 Protocadherin gamma-B5 chr5 Not Cancer Driver No 542-580 39 7.21e-03 0.0 14 16.09 87 STAD, LUAD SKCM, READ, LUSC, STAD, LUAD, COAD
ZCWPW1 Q9H0M4 ZCWPW1 Zinc finger CW-type PWWP domain protein 1 chr7 Not Cancer Driver No 253-284 32 7.21e-03 0.0 14 15.56 90 SKCM KIRC, UCEC, BRCA, BLCA, SARC, SKCM
MAN2B2 Q9Y2E5 MAN2B2 Epididymis-specific alpha-mannosidase chr4 Not Cancer Driver No 309-346 38 7.22e-03 0.0 16 11.27 142 - CESC, LGG, UCEC, STAD, SKCM, READ, LUSC, LUAD, PAAD
UMOD_ENST00000302509 P07911 UMOD Uromodulin chr16 Not Cancer Driver No 375-400 26 7.22e-03 0.0 16 12.7 126 - PAAD, COAD, SKCM, GBM, STAD, LUSC, BRCA, UCEC
DSPP_ENST00000282478 Q9NZW4 DSPP Dentin sialophosphoprotein chr4 Not Cancer Driver No 205-208 4 7.22e-03 100.0 7 3.24 216 SKCM UCEC, SKCM
TAOK2 Q9UL54 TAOK2 Serine/threonine-protein kinase TAO2 chr16 Not Cancer Driver No 759-762 4 7.23e-03 100.0 7 3.57 196 GBM STAD, GBM
AGL_ENST00000361915 P35573 AGL Glycogen debranching enzyme chr1 Not Cancer Driver No 622-626 5 7.23e-03 0.0 7 3.8 184 OV UCEC, KIRC, OV, READ
TMC2 Q8TDI7 TMC2 Transmembrane channel-like protein 2 chr20 Not Cancer Driver No 430-430 1 7.23e-03 0.0 7 3.87 181 SKCM BRCA, SKCM, READ
PRSS1 P07477 PRSS1 Serine protease 1 chr7 Not Cancer Driver No 206-215 10 7.24e-03 0.0 16 13.22 121 SKCM SKCM, UCEC, LUAD, STAD, BLCA, KIRC
MAP2K7_ENST00000397979 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 chr19 Compendium Yes 275-327 53 7.24e-03 22.22 26 29.21 89 STAD SARC, PAAD, STAD, LUSC, UCEC, COAD, SKCM, LUAD
OR4K2 Q8NGD2 OR4K2 Olfactory receptor 4K2 chr14 Not Cancer Driver No 207-207 1 7.24e-03 0.0 7 3.85 182 UCEC LUSC, THCA, LUAD, LGG, UCEC, BLCA
RPAP1 Q9BWH6 RPAP1 RNA polymerase II-associated protein 1 chr15 Not Cancer Driver No 135-137 3 7.24e-03 100.0 8 4.4 182 BRCA, SKCM BRCA, UCEC, SKCM
RTL1 A6NKG5 RTL1 Retrotransposon-like protein 1 chr14 Not Cancer Driver No 614-617 4 7.25e-03 100.0 7 3.52 199 GBM, SKCM GBM, SARC, BLCA, SKCM
BNC1 Q01954 BNC1 Zinc finger protein basonuclin-1 chr15 Not Cancer Driver No 105-107 3 7.26e-03 0.0 9 4.62 195 - STAD, GBM, BRCA, KIRC, READ, OV, LUSC
WDR90 Q96KV7 WDR90 WD repeat-containing protein 90 chr16 Not Cancer Driver No 536-540 5 7.26e-03 0.0 14 6.57 213 COAD, READ SKCM, COAD, UCEC, READ
OTX1_ENST00000366671 P32242 OTX1 Homeobox protein OTX1 chr2 Not Cancer Driver No 315-325 11 7.27e-03 100.0 11 16.18 68 GBM KIRC, GBM, LGG, LUAD, THCA
ANKRD36C Q5JPF3 ANKRD36C Ankyrin repeat domain-containing protein 36C chr2 Not Cancer Driver No 1411-1411 1 7.27e-03 0.0 7 3.5 200 KIRC, PRAD, SKCM KIRC, LUAD, PRAD, SKCM
PCDHB13 Q9Y5F0 PCDHB13 Protocadherin beta-13 chr5 Not Cancer Driver No 524-559 36 7.30e-03 0.0 23 11.17 206 - GBM, LUSC, BRCA, UCEC, BLCA, SKCM, READ, LUAD, OV, HNSC, PAAD
DDX60 Q8IY21 DDX60 Probable ATP-dependent RNA helicase DDX60 chr4 Not Cancer Driver No 735-737 3 7.30e-03 0.0 7 3.1 226 SARC SARC, GBM, UCEC, SKCM, PRAD, COAD
FHOD3_ENST00000359247 Q2V2M9 FHOD3 FH1/FH2 domain-containing protein 3 chr18 Not Cancer Driver No 461-463 3 7.31e-03 33.33 7 3.23 217 THCA COAD, THCA, UCEC, KIRC, HNSC, GBM
NUDT12 Q9BQG2 NUDT12 NAD-capped RNA hydrolase NUDT12 chr5 Not Cancer Driver No 67-76 10 7.32e-03 0.0 9 13.64 66 - HNSC, STAD, SKCM, THCA, LUSC, BLCA, KIRC, LUAD
PARP4 Q9UKK3 PARP4 Protein mono-ADP-ribosyltransferase PARP4 chr13 Compendium Yes 1059-1063 5 7.33e-03 20.0 7 3.1 226 BRCA BLCA, UCEC, KIRC, BRCA
SLC9A8_ENST00000361573 Q9Y2E8 SLC9A8 Sodium/hydrogen exchanger 8 chr20 Not Cancer Driver No 525-551 27 7.34e-03 44.44 13 17.81 73 STAD UCEC, READ, LUAD, STAD, LUSC, BRCA
KY Q8NBH2 KY Kyphoscoliosis peptidase chr3 Not Cancer Driver No 479-510 32 7.34e-03 15.62 14 14.29 98 OV STAD, SKCM, CESC, LUSC, COAD, LUAD, LAML, UCEC, OV
ZNF646 O15015 ZNF646 Zinc finger protein 646 chr16 Not Cancer Driver No 377-380 4 7.36e-03 0.0 7 3.03 231 GBM GBM, STAD, LUSC
DGKD Q16760 DGKD Diacylglycerol kinase delta chr2 Not Cancer Driver No 162-204 43 7.37e-03 0.0 16 10.0 160 LUSC, SKCM UCEC, BRCA, LUSC, BLCA, SARC, SKCM, GBM, KIRC
DICER1 Q9UPY3 DICER1 Endoribonuclease Dicer chr14 Census, Compendium Yes 1340-1344 5 7.38e-03 0.0 7 2.62 267 UCEC COAD, BRCA, SKCM, UCEC, STAD
YJEFN3 A6XGL0 YJEFN3 YjeF N-terminal domain-containing protein 3 chr19 Not Cancer Driver No 109-138 30 7.38e-03 0.0 12 34.29 35 - OV, BLCA, GBM, LUAD, PRAD, STAD, SKCM, BRCA, UCEC
ZBTB7B_ENST00000368426 O15156 ZBTB7B Zinc finger and BTB domain-containing protein 7B chr1 Compendium Yes 387-388 2 7.38e-03 0.0 6 5.83 103 READ, UCEC, BLCA READ, UCEC, BLCA, KIRC
ANKRD53 Q8N9V6 ANKRD53 Ankyrin repeat domain-containing protein 53 chr2 Not Cancer Driver No 71-87 17 7.39e-03 100.0 12 19.35 62 LUAD STAD, SKCM, LUAD, READ, REO
RGS21 Q2M5E4 RGS21 Regulator of G-protein signaling 21 chr1 Not Cancer Driver No 148-151 4 7.39e-03 100.0 10 18.18 55 LUAD STAD, LUSC, LUAD, SKCM
A2M P01023 A2M Alpha-2-macroglobulin chr12 Not Cancer Driver No 174-176 3 7.40e-03 0.0 9 3.44 262 COAD COAD, UCEC, BRCA, SKCM, LUAD, READ
CROCC Q5TZA2 CROCC Rootletin chr1 Not Cancer Driver No 511-511 1 7.40e-03 100.0 7 2.67 262 COAD, READ COAD, READ
PCDHA2 Q9Y5H9 PCDHA2 Protocadherin alpha-2 chr5 Not Cancer Driver No 512-527 16 7.41e-03 0.0 18 5.34 337 LUAD, SKCM UCEC, LUAD, CESC, SKCM, LUSC, LIHC
ENTPD4 Q9Y227 ENTPD4 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 Not Cancer Driver No 574-601 28 7.41e-03 42.86 13 19.12 68 STAD, READ OV, SKCM, LUAD, STAD, READ
GPSM1 Q86YR5 GPSM1 G-protein-signaling modulator 1 chr9 Not Cancer Driver No 574-605 32 7.41e-03 100.0 12 17.39 69 - STAD, UCEC, READ, LUAD, CESC, SKCM, BLCA, OV
ARID1A O14497 ARID1A AT-rich interactive domain-containing protein 1A chr1 Census, Compendium Yes 2087-2087 1 7.46e-03 0.0 7 2.55 275 SKCM LIHC, STAD, SKCM, CESC, LUAD, LUSC
OR5F1 O95221 OR5F1 Olfactory receptor 5F1 chr11 Not Cancer Driver No 41-50 10 7.46e-03 0.0 15 10.0 150 LUAD, SKCM LUAD, HNSC, STAD, SKCM, LUSC, BRCA
SHANK2_ENST00000601538 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 chr11 Not Cancer Driver No 1128-1131 4 7.46e-03 100.0 7 2.3 304 SKCM PRAD, SKCM, LUAD
SCARF1 Q14162 SCARF1 Scavenger receptor class F member 1 chr17 Not Cancer Driver No 577-614 38 7.47e-03 100.0 14 15.56 90 STAD COAD, CESC, SKCM, UCEC, KIRC, STAD
PTPRK_ENST00000368215 Q15262 PTPRK Receptor-type tyrosine-protein phosphatase kappa chr6 Census, Compendium Yes 358-360 3 7.47e-03 0.0 7 2.4 292 SKCM SKCM, CESC, BLCA
CNOT1 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 chr16 Not Cancer Driver No 591-593 3 7.48e-03 0.0 8 2.31 347 COAD, UCEC COAD, LUAD, LUSC, UCEC
MAP3K2_ENST00000344908 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 chr2 Not Cancer Driver No 329-355 27 7.48e-03 77.78 14 18.42 76 SKCM, OV SKCM, BLCA, GBM, LUSC, STAD, READ, OV
MTO1_ENST00000370300 Q9Y2Z2 MTO1 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 346-377 32 7.48e-03 9.38 11 15.71 70 SKCM, BRCA COAD, UCEC, SKCM, BRCA, LUAD
PKD2L2 Q9NZM6 PKD2L2 Polycystic kidney disease 2-like 2 protein chr5 Not Cancer Driver No 118-140 23 7.48e-03 0.0 13 14.77 88 UCEC, LUAD SKCM, COAD, BRCA, UCEC, LUAD, STAD
TNRC18 O15417 TNRC18 Trinucleotide repeat-containing gene 18 protein chr7 Not Cancer Driver No 2818-2822 5 7.48e-03 100.0 7 2.16 324 SKCM, STAD SKCM, READ, STAD, LUAD
COG8 H3BQV3 COG8 Conserved oligomeric Golgi complex subunit 8 chr16 Not Cancer Driver No 214-248 35 7.49e-03 100.0 18 16.07 112 SKCM SKCM, LUAD, READ, GBM, BLCA
SMG1 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 chr16 Not Cancer Driver No 12-13 2 7.49e-03 100.0 7 2.01 348 STAD STAD, KIRC, LUSC, HNSC, PRAD, LGG
CFAP54 Q96N23 CFAP54 Cilia- and flagella-associated protein 54 chr12 Not Cancer Driver No 2372-2377 6 7.49e-03 100.0 7 2.07 338 SKCM SKCM
ING3 Q9NXR8 ING3 Inhibitor of growth protein 3 chr7 Not Cancer Driver No 188-227 40 7.51e-03 100.0 10 22.73 44 UCEC HNSC, LUSC, LUAD, BRCA, SKCM, UCEC
EP300 Q09472 EP300 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1627-1629 3 7.52e-03 0.0 10 2.99 335 UCEC UCEC, BLCA, SKCM, STAD
CSH2 P0DML3 CSH2 Chorionic somatomammotropin hormone 2 chr17 Not Cancer Driver No 154-160 7 7.53e-03 71.43 9 16.98 53 - BRCA, LGG, PRAD, GBM, LUAD, OV
FAM155B O75949 NALF2 NALCN channel auxiliary factor 2 chrX Not Cancer Driver No 407-416 10 7.53e-03 100.0 9 16.07 56 - LUAD, CESC, UCEC, OV, READ, SKCM
GUCA1C O95843 GUCA1C Guanylyl cyclase-activating protein 3 chr3 Not Cancer Driver No 38-42 5 7.53e-03 0.0 11 18.33 60 SKCM SKCM, UCEC, OV, BRCA
POTEB2 H3BUK9 POTEB2 POTE ankyrin domain family member B2 chr15 Not Cancer Driver No 406-421 16 7.53e-03 100.0 11 16.92 65 - COAD, CESC, KIRC, SKCM, SARC, UCEC, LUSC
RGMA_ENST00000329082 Q96B86 RGMA Repulsive guidance molecule A chr15 Not Cancer Driver No 424-438 15 7.54e-03 100.0 19 26.76 71 READ COAD, STAD, BRCA, SARC, READ
SNX9 Q9Y5X1 SNX9 Sorting nexin-9 chr6 Not Cancer Driver No 295-320 26 7.54e-03 0.0 11 15.49 71 SKCM, GBM KIRC, LUAD, SKCM, GBM, UCEC
MYO3A Q8NEV4 MYO3A Myosin-IIIa chr10 Not Cancer Driver No 525-525 1 7.57e-03 0.0 8 1.73 462 KIRC, OV KIRC, SKCM, OV, READ
EPPK1 P58107 EPPK1 Epiplakin chr8 Not Cancer Driver No 1780-1786 7 7.57e-03 100.0 7 1.64 428 HNSC COAD, STAD, LGG, UCEC, HNSC, SKCM
IGSF10 Q6WRI0 IGSF10 Immunoglobulin superfamily member 10 chr3 Not Cancer Driver No 682-722 41 7.57e-03 100.0 18 3.97 453 - OV, GBM, STAD, HNSC, CESC, SKCM, KIRC, COAD, LUAD
GIMAP1 Q8WWP7 GIMAP1 GTPase IMAP family member 1 chr7 Not Cancer Driver No 96-126 31 7.58e-03 0.0 25 24.27 103 SKCM LUSC, READ, GBM, HNSC, PRAD, SKCM, UCEC, CESC, STAD, OV, BLCA, LUAD
C1orf122 Q6ZSJ8 C1orf122 Uncharacterized protein C1orf122 chr1 Not Cancer Driver No 82-106 25 7.58e-03 100.0 6 100.0 6 OV, CESC OV, CESC, KIRC
CSTB P04080 CSTB Cystatin-B chr21 Not Cancer Driver No 72-76 5 7.58e-03 0.0 5 71.43 7 - CESC, COAD, BLCA, LIHC, HNSC
SYNDIG1 Q9H7V2 SYNDIG1 Synapse differentiation-inducing gene protein 1 chr20 Not Cancer Driver No 149-187 39 7.58e-03 100.0 24 26.67 90 SKCM READ, LUAD, SARC, STAD, COAD, SKCM, PRAD, LUSC, BLCA, UCEC, LIHC
LAMA5 O15230 LAMA5 Laminin subunit alpha-5 chr20 Not Cancer Driver No 3079-3079 1 7.58e-03 100.0 16 3.52 455 COAD, READ COAD, READ
CCDC9B Q6ZUT6 CCDC9B Coiled-coil domain-containing protein 9B chr15 Not Cancer Driver No 463-508 46 7.59e-03 100.0 18 23.68 76 BLCA, COAD BLCA, CESC, COAD, LUSC, HNSC
FTCD_ENST00000291670 O95954 FTCD Formimidoyltransferase-cyclodeaminase chr21 Not Cancer Driver No 191-235 45 7.59e-03 0.0 18 18.75 96 COAD SARC, COAD, READ, SKCM, KIRC, STAD, LUSC, UCEC, LUAD, LGG
DNAJC5B Q9UF47 DNAJC5B DnaJ homolog subfamily C member 5B chr8 Not Cancer Driver No 65-70 6 7.59e-03 0.0 10 15.62 64 - BRCA, LUAD, SKCM, LUSC, CESC, UCEC, STAD
THNSL2 Q86YJ6 THNSL2 Threonine synthase-like 2 chr2 Not Cancer Driver No 69-90 22 7.60e-03 0.0 12 16.44 73 - BRCA, LUAD, LUSC, UCEC, OV, SKCM
ADAMTS20 P59510 ADAMTS20 A disintegrin and metalloproteinase with thrombospondin motifs 20 chr12 Not Cancer Driver No 541-542 2 7.61e-03 0.0 7 1.4 501 LUAD, OV LUSC, SKCM, LUAD, HNSC, OV
KCTD16_ENST00000512467 Q68DU8 KCTD16 BTB/POZ domain-containing protein KCTD16 chr5 Not Cancer Driver No 335-351 17 7.62e-03 100.0 15 13.64 110 - LUAD, BRCA, READ, SKCM, GBM, BLCA, UCEC, LUSC
MOV10L1_ENST00000545383 Q9BXT6 MOV10L1 RNA helicase Mov10l1 chr22 Not Cancer Driver No 419-457 39 7.62e-03 0.0 16 8.38 191 LUAD HNSC, STAD, UCEC, COAD, LUSC, BRCA, LUAD, SKCM
HUWE1_ENST00000262854 Q7Z6Z7 HUWE1 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 3737-3739 3 7.65e-03 100.0 7 1.04 670 OV, UCEC HNSC, OV, STAD, LUAD, UCEC
PYGL P06737 PYGL Glycogen phosphorylase, liver form chr14 Not Cancer Driver No 161-195 35 7.65e-03 0.0 13 13.13 99 SKCM KIRC, LUSC, HNSC, SKCM, BLCA, LIHC, BRCA, UCEC
ZNF829_ENST00000391711 Q3KNS6 ZNF829 Zinc finger protein 829 chr19 Not Cancer Driver No 194-203 10 7.66e-03 60.0 9 10.84 83 BLCA BLCA, COAD, BRCA, GBM, LUSC
GPR12_ENST00000381436 P47775 GPR12 G-protein coupled receptor 12 chr13 Not Cancer Driver No 176-186 11 7.67e-03 0.0 11 15.94 69 SKCM LIHC, SKCM, UCEC, PAAD, STAD, BRCA, CESC, READ
RAPSN Q13702 RAPSN 43 kDa receptor-associated protein of the synapse chr11 Not Cancer Driver No 161-203 43 7.67e-03 6.98 12 30.0 40 - LUAD, BLCA, LGG, LUSC, UCEC, STAD, LAML, READ
WARS2 Q9UGM6 WARS2 Tryptophan--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 292-303 12 7.67e-03 0.0 13 19.4 67 UCEC SARC, LUSC, STAD, UCEC, HNSC, COAD, BRCA
OR5D18 Q8NGL1 OR5D18 Olfactory receptor 5D18 chr11 Not Cancer Driver No 120-129 10 7.67e-03 0.0 15 8.93 168 - LUSC, HNSC, COAD, LIHC, GBM, UCEC, LGG, LUAD
HCN1 O60741 HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 Not Cancer Driver No 714-724 11 7.67e-03 100.0 19 4.4 432 LUAD COAD, UCEC, LUAD, SKCM, LUSC, GBM, HNSC
APBB1IP Q7Z5R6 APBB1IP Amyloid beta A4 precursor protein-binding family B member 1-interacting protein chr10 Not Cancer Driver No 262-300 39 7.69e-03 33.33 22 16.92 130 SKCM LGG, COAD, HNSC, UCEC, OV, SKCM, PRAD, BLCA, BRCA, LUSC
TMC2 Q8TDI7 TMC2 Transmembrane channel-like protein 2 chr20 Not Cancer Driver No 471-499 29 7.71e-03 10.34 16 8.84 181 - LUAD, UCEC, LUSC, STAD, BLCA, SARC, GBM, OV, BRCA, LIHC, LGG
C7orf55-LUC7L2 Q96HJ9-2 C7orf55-LUC7L2 Isoform 2 of Protein FMC1 homolog chr7 Not Cancer Driver No 264-275 12 7.72e-03 100.0 9 13.24 68 SKCM BLCA, LUSC, UCEC, SKCM, STAD
GH2_ENST00000423893 P01242 GH2 Growth hormone variant chr17 Not Cancer Driver No 205-209 5 7.72e-03 0.0 9 16.36 55 - LGG, GBM, BRCA, LUAD, UCEC, LIHC, BLCA, READ, HNSC
PPIL2_ENST00000335025 Q13356 PPIL2 RING-type E3 ubiquitin-protein ligase PPIL2 chr22 Not Cancer Driver No 35-44 10 7.72e-03 0.0 10 15.62 64 SKCM LGG, BRCA, SKCM, STAD, KIRC, UCEC
FAM47C Q5HY64 FAM47C Putative protein FAM47C chrX Census Yes 644-655 12 7.72e-03 100.0 17 3.67 463 LGG, PRAD OV, LGG, STAD, LUAD, PRAD
CELF4 Q9BZC1 CELF4 CUGBP Elav-like family member 4 chr18 Not Cancer Driver No 304-318 15 7.72e-03 100.0 15 14.02 107 SKCM SKCM, GBM, LUSC, READ, LUAD, OV, STAD, BLCA
TDG Q13569 TDG G/T mismatch-specific thymine DNA glycosylase chr12 Not Cancer Driver No 197-209 13 7.73e-03 0.0 12 16.0 75 BLCA COAD, LGG, BLCA, LUSC, KIRC, SKCM, OV
LHB P01229 LHB Lutropin subunit beta chr19 Not Cancer Driver No 112-120 9 7.75e-03 0.0 8 38.1 21 COAD LIHC, BLCA, BRCA, LUAD, COAD, UCEC, LUSC
MTX1 Q13505 MTX1 Metaxin-1 chr1 Not Cancer Driver No 206-237 32 7.75e-03 0.0 8 32.0 25 LUSC LUAD, LUSC, PRAD, BLCA, CESC, STAD, UCEC
KCNAB1 Q14722 KCNAB1 Voltage-gated potassium channel subunit beta-1 chr3 Not Cancer Driver No 112-145 34 7.75e-03 0.0 20 22.47 89 - BRCA, LUSC, SKCM, LUAD, CESC, LIHC, HNSC, COAD
ADGRB3_ENST00000546190 O60242 ADGRB3 Adhesion G protein-coupled receptor B3 chr6 Not Cancer Driver No 1168-1186 19 7.76e-03 100.0 25 4.46 560 SKCM LUAD, LUSC, SKCM, PRAD, UCEC, COAD
TNR Q92752 TNR Tenascin-R chr1 Not Cancer Driver No 926-940 15 7.77e-03 0.0 19 3.8 500 SKCM SARC, SKCM, BLCA, PAAD, LIHC, LUAD, LUSC
BEND6 Q5SZJ8 BEND6 BEN domain-containing protein 6 chr6 Not Cancer Driver No 55-60 6 7.77e-03 100.0 9 15.0 60 OV OV, BLCA, HNSC
RSPH10B2 B2RC85 RSPH10B2 Radial spoke head 10 homolog B2 chr7 Compendium Yes 52-64 13 7.77e-03 100.0 11 15.28 72 - UCEC, READ, LUAD, OV, SKCM, KIRC
ZAN_ENST00000618565 Q9Y493 ZAN Zonadhesin chr7 Not Cancer Driver No 629-664 36 7.78e-03 100.0 18 3.31 543 - COAD, LUSC, LUAD, BLCA, KIRC, UCEC, SKCM, BRCA
MYCBP2_ENST00000357337 O75592 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 chr13 Not Cancer Driver No 799-853 55 7.80e-03 100.0 23 3.77 610 COAD CESC, LUAD, COAD, BRCA, KIRC, BLCA, SKCM
FAT2 Q9NYQ8 FAT2 Protocadherin Fat 2 chr5 Compendium Yes 2578-2589 12 7.80e-03 100.0 4 0.62 648 BLCA STAD, BLCA, KIRC, GBM, UCEC
MAST2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 chr1 Not Cancer Driver No 720-769 50 7.80e-03 4.0 16 8.51 188 LUSC BRCA, SKCM, OV, LUAD, BLCA, COAD, UCEC, LUSC
HEY2 Q9UBP5 HEY2 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 Not Cancer Driver No 134-140 7 7.83e-03 0.0 9 13.85 65 - READ, SKCM, UCEC, BRCA, HNSC, STAD, LGG, COAD
IRX4_ENST00000231357 P78413 IRX4 Iroquois-class homeodomain protein IRX-4 chr5 Not Cancer Driver No 204-218 15 7.84e-03 100.0 13 17.33 75 - HNSC, UCEC, PRAD, COAD, BRCA, LUSC, LUAD, STAD, CESC
PTGDR Q13258 PTGDR Prostaglandin D2 receptor chr14 Not Cancer Driver No 244-257 14 7.84e-03 100.0 11 14.86 74 STAD, BLCA STAD, BLCA, LUAD, LUSC, SKCM
SHOX O15266 SHOX Short stature homeobox protein chrX Not Cancer Driver No 63-72 10 7.84e-03 100.0 11 14.1 78 LUAD LUSC, LUAD, UCEC, PRAD, READ, SKCM, BLCA
DLX4 Q92988 DLX4 Homeobox protein DLX-4 chr17 Not Cancer Driver No 185-205 21 7.85e-03 100.0 12 34.29 35 SKCM SKCM, PRAD, LUAD, DLBC, KIRC, OV
TSPEAR_ENST00000613245 Q8WU66 TSPEAR Thrombospondin-type laminin G domain and EAR repeat-containing protein chr21 Not Cancer Driver No 191-225 35 7.88e-03 0.0 19 14.39 132 - HNSC, UCEC, LUAD, OV, KIRC, SKCM, STAD, LUSC, GBM
MMP11 P24347 MMP11 Stromelysin-3 chr22 Not Cancer Driver No 38-45 8 7.88e-03 100.0 10 15.87 63 COAD, READ COAD, SKCM, LUSC, READ
SCGN O76038 SCGN Secretagogin chr6 Not Cancer Driver No 97-103 7 7.88e-03 28.57 11 14.29 77 - STAD, SARC, KIRC, COAD, SKCM, HNSC, UCEC
CUL4B Q13620 CUL4B Cullin-4B chrX Not Cancer Driver No 105-139 35 7.94e-03 100.0 15 10.87 138 SKCM BRCA, BLCA, LUSC, CESC, LUAD, SKCM, LGG
CTDP1 Q9Y5B0 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase chr18 Not Cancer Driver No 775-810 36 7.97e-03 100.0 15 12.4 121 - OV, LUSC, KIRC, LIHC, UCEC, SKCM, STAD, LUAD, COAD
KRTCAP3 Q53RY4 KRTCAP3 Keratinocyte-associated protein 3 chr2 Not Cancer Driver No 82-88 7 7.97e-03 0.0 6 31.58 19 HNSC LUSC, OV, LGG, BLCA, HNSC
RPL31_ENST00000264258 P62899 RPL31 60S ribosomal protein L31 chr2 Not Cancer Driver No 94-97 4 7.97e-03 25.0 6 31.58 19 BLCA HNSC, COAD, BLCA, UCEC
ZNF705B P0CI00 ZNF705B Putative zinc finger protein 705B chr8 Not Cancer Driver No 90-92 3 7.97e-03 100.0 10 45.45 22 BRCA, KIRC LUSC, BRCA, KIRC, SKCM
ZNF671 Q8TAW3 ZNF671 Zinc finger protein 671 chr19 Not Cancer Driver No 9-51 43 7.97e-03 95.35 17 18.48 92 - READ, BLCA, LUAD, HNSC, SKCM, LUSC
GOT2 P00505 GOT2 Aspartate aminotransferase, mitochondrial chr16 Not Cancer Driver No 346-355 10 7.99e-03 0.0 12 18.18 66 BLCA LGG, PRAD, LUSC, LUAD, BLCA, UCEC
SYT13 Q7L8C5 SYT13 Synaptotagmin-13 chr11 Not Cancer Driver No 221-230 10 7.99e-03 0.0 9 12.68 71 SKCM GBM, LUSC, SKCM, LUAD
TMPRSS6_ENST00000346753 Q8IU80 TMPRSS6 Transmembrane protease serine 6 chr22 Not Cancer Driver No 281-327 47 8.00e-03 12.5 18 13.85 130 - READ, LUSC, KIRC, BRCA, SKCM, OV, COAD, CESC, STAD, GBM
PRB3_ENST00000381842 Q04118 PRB3 Basic salivary proline-rich protein 3 chr12 Not Cancer Driver No 86-97 12 8.00e-03 100.0 14 12.96 108 SKCM UCEC, OV, READ, LUSC, LGG, SKCM, BRCA
GALNT17 Q6IS24 GALNT17 Polypeptide N-acetylgalactosaminyltransferase 17 chr7 Not Cancer Driver No 282-298 17 8.02e-03 0.0 23 7.54 305 SKCM READ, STAD, SKCM, GBM, UCEC, HNSC, BLCA, LUSC
LY75-CD302_ENST00000505052 O60449-3 LY75-CD302 Isoform 3 of Lymphocyte antigen 75 chr2 Compendium Yes 1152-1191 40 8.04e-03 100.0 15 6.2 242 LUAD BLCA, LUAD, STAD, SKCM, LIHC, UCEC, LGG
OR10G2 Q8NGC3 OR10G2 Olfactory receptor 10G2 chr14 Not Cancer Driver No 234-245 12 8.04e-03 0.0 13 17.11 76 - READ, LUAD, BLCA, LGG, LUSC, CESC, KIRC, HNSC, SARC, STAD
SIGLEC14 Q08ET2 SIGLEC14 Sialic acid-binding Ig-like lectin 14 chr19 Not Cancer Driver No 213-225 13 8.04e-03 46.15 12 16.44 73 - LIHC, LGG, DLBC, LUSC, LUAD, SKCM, OV, KIRC, GBM, UCEC
ADH1C P00326 ADH1C Alcohol dehydrogenase 1C chr4 Not Cancer Driver No 256-266 11 8.05e-03 0.0 14 12.07 116 SKCM CESC, LUSC, KIRC, SKCM
STXBP5 Q5T5C0 STXBP5 Syntaxin-binding protein 5 chr6 Not Cancer Driver No 773-808 36 8.05e-03 50.0 14 10.85 129 LUAD LIHC, LUSC, CESC, SKCM, BRCA, READ, LUAD
CDH2 P19022 CDH2 Cadherin-2 chr18 Not Cancer Driver No 491-513 23 8.08e-03 0.0 17 7.11 239 SKCM LUAD, STAD, READ, BLCA, PAAD, COAD, CESC, LUSC, SKCM
KPNA6 O60684 KPNA6 Importin subunit alpha-7 chr1 Not Cancer Driver No 16-29 14 8.08e-03 100.0 9 12.86 70 SKCM COAD, CESC, UCEC, READ, SKCM
NPIPB15 A6NHN6 NPIPB15 Nuclear pore complex-interacting protein family member B15 chr16 Not Cancer Driver No 93-101 9 8.08e-03 100.0 9 13.64 66 SKCM UCEC, BRCA, LGG, SKCM, BLCA
POLI Q9UNA4 POLI DNA polymerase iota chr18 Not Cancer Driver No 372-390 19 8.08e-03 36.84 10 12.2 82 LUAD READ, BLCA, SKCM, LUAD, LUSC, STAD, UCEC
KRI1 Q8N9T8 KRI1 Protein KRI1 homolog chr19 Not Cancer Driver No 321-348 28 8.09e-03 7.14 15 15.62 96 LUSC OV, GBM, LUSC, BLCA, LGG, BRCA, KIRC, SKCM
CRAMP1 Q96RY5 CRAMP1 Protein cramped-like chr16 Not Cancer Driver No 753-796 44 8.10e-03 100.0 16 13.01 123 STAD BLCA, UCEC, PRAD, READ, STAD, COAD
OR5M9 Q8NGP3 OR5M9 Olfactory receptor 5M9 chr11 Not Cancer Driver No 220-230 11 8.10e-03 0.0 13 11.71 111 - LIHC, KIRC, COAD, STAD, READ, HNSC, UCEC, SKCM, LUSC
ARAF_ENST00000377045 P10398 ARAF Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 213-218 6 8.13e-03 100.0 9 10.71 84 LUAD BLCA, SKCM, GBM, COAD, LUAD
CLNK Q7Z7G1 CLNK Cytokine-dependent hematopoietic cell linker chr4 Not Cancer Driver No 256-263 8 8.13e-03 100.0 9 10.47 86 - GBM, KIRC, CESC, BLCA, SKCM, COAD, LUSC, LIHC
CYC1 P08574 CYC1 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 163-166 4 8.13e-03 0.0 9 13.85 65 GBM GBM, COAD
DBX2 Q6ZNG2 DBX2 Homeobox protein DBX2 chr12 Not Cancer Driver No 154-160 7 8.13e-03 100.0 10 13.89 72 - HNSC, BRCA, UCEC, LUAD, SKCM, LIHC
PRKCZ Q05513 PRKCZ Protein kinase C zeta type chr1 Not Cancer Driver No 251-260 10 8.13e-03 0.0 10 14.29 70 OV UCEC, LIHC, PRAD, OV
CASKIN1 Q8WXD9 CASKIN1 Caskin-1 chr16 Not Cancer Driver No 174-217 44 8.13e-03 36.36 19 16.24 117 - LIHC, UCEC, SKCM, STAD, GBM, OV, HNSC, LUAD, LUSC
ITPK1 Q13572 ITPK1 Inositol-tetrakisphosphate 1-kinase chr14 Not Cancer Driver No 251-260 10 8.17e-03 0.0 9 12.16 74 BLCA BRCA, LUSC, HNSC, BLCA, PRAD
NUTM2G Q5VZR2 NUTM2G NUT family member 2G chr9 Not Cancer Driver No 57-73 17 8.17e-03 100.0 10 13.7 73 LUAD HNSC, LUSC, BRCA, LUAD, SKCM, GBM
EN1 Q05925 EN1 Homeobox protein engrailed-1 chr2 Not Cancer Driver No 348-382 35 8.20e-03 36.11 14 33.33 42 - BRCA, LIHC, LUSC, STAD, SKCM, GBM, BLCA, COAD, LUAD
OR2A5_ENST00000408906 Q96R48 OR2A5 Olfactory receptor 2A5 chr7 Not Cancer Driver No 66-74 9 8.20e-03 0.0 14 12.07 116 SKCM LUAD, SKCM, LUSC
ADRA2B P18089 ADRA2B Alpha-2B adrenergic receptor chr2 Not Cancer Driver No 153-163 11 8.21e-03 81.82 9 12.0 75 OV, LUSC COAD, LUAD, OV, LUSC, SKCM
FAM217B Q9NTX9 FAM217B Protein FAM217B chr20 Not Cancer Driver No 137-143 7 8.21e-03 100.0 9 13.24 68 GBM LUAD, LUSC, GBM
OTC P00480 OTC Ornithine transcarbamylase, mitochondrial chrX Not Cancer Driver No 208-216 9 8.21e-03 0.0 9 9.78 92 - LUSC, LUAD, UCEC, BLCA, SKCM, SARC
PRR23B Q6ZRT6 PRR23B Proline-rich protein 23B chr3 Not Cancer Driver No 167-173 7 8.22e-03 100.0 14 12.07 116 SKCM STAD, LUSC, PRAD, HNSC, SKCM, LGG, LIHC, KIRC
PROX2 Q3B8N5 PROX2 Prospero homeobox protein 2 chr14 Not Cancer Driver No 301-308 8 8.25e-03 100.0 10 13.16 76 SKCM COAD, UCEC, SKCM, STAD
TTN_ENST00000615779 Q8WZ42 TTN Titin chr2 Not Cancer Driver No 5882-5938 57 8.26e-03 100.0 34 0.43 7986 - UCEC, READ, STAD, COT, CESC, LUSC, HNSC, LIHC, SKCM, BLCA, KIRC, GBM, LUAD
CBLN2 Q8IUK8 CBLN2 Cerebellin-2 chr18 Not Cancer Driver No 72-79 8 8.27e-03 100.0 12 15.19 79 - BRCA, SKCM, HNSC, LUAD, LUSC, READ, COAD, STAD
PPP3CA Q08209 PPP3CA Protein phosphatase 3 catalytic subunit alpha chr4 Compendium Yes 474-487 14 8.27e-03 100.0 12 13.79 87 LUAD LUAD, SKCM, READ, LUSC, STAD
ODAPH_ENST00000311623 Q17RF5 ODAPH Odontogenesis associated phosphoprotein chr4 Not Cancer Driver No 25-38 14 8.27e-03 100.0 12 38.71 31 - LUAD, KIRC, BLCA, UCEC, LGG, READ, SKCM, LIHC
FNDC8 Q8TC99 FNDC8 Fibronectin type III domain-containing protein 8 chr17 Not Cancer Driver No 117-154 38 8.28e-03 100.0 9 21.95 41 - SKCM, LUAD, PRAD, READ, BLCA, STAD, LIHC, UCEC
NUTM2F A1L443 NUTM2F NUT family member 2F chr9 Not Cancer Driver No 350-364 15 8.29e-03 100.0 9 10.11 89 COAD HNSC, COAD, CESC, LUAD, SKCM, READ
CACNG3 O60359 CACNG3 Voltage-dependent calcium channel gamma-3 subunit chr16 Not Cancer Driver No 133-138 6 8.30e-03 0.0 14 11.11 126 COAD LUSC, GBM, PAAD, READ, COAD, LUAD
KEAP1_ENST00000393623 Q14145 KEAP1 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 268-280 13 8.30e-03 0.0 17 7.11 239 LUAD KIRC, HNSC, LUSC, LIHC, LUAD
COL6A1 P12109 COL6A1 Collagen alpha-1(VI) chain chr21 Not Cancer Driver No 109-132 24 8.31e-03 0.0 9 5.96 151 BRCA UCEC, COAD, LUAD, READ, GBM, BRCA, LUSC
OR10J1 P30954 OR10J1 Olfactory receptor 10J1 chr1 Not Cancer Driver No 312-320 9 8.31e-03 55.56 14 10.14 138 SKCM UCEC, CESC, SKCM, LUAD, READ, STAD
OR4C13 Q8NGP0 OR4C13 Olfactory receptor 4C13 chr11 Not Cancer Driver No 83-91 9 8.32e-03 0.0 7 4.93 142 READ READ, LUSC, LUAD, UCEC, COAD, SKCM
RAD50 Q92878 RAD50 DNA repair protein RAD50 chr5 Not Cancer Driver No 66-87 22 8.33e-03 0.0 11 7.01 157 - LUAD, LUSC, STAD, BRCA, SKCM, UCEC, BLCA, COAD
NTSR2 O95665 NTSR2 Neurotensin receptor type 2 chr2 Not Cancer Driver No 285-294 10 8.33e-03 0.0 11 11.58 95 - LUAD, UCEC, HNSC, LUSC, BRCA, STAD
RNF133 Q8WVZ7 RNF133 E3 ubiquitin-protein ligase RNF133 chr7 Not Cancer Driver No 262-270 9 8.33e-03 0.0 11 14.47 76 SKCM SKCM, OV, KIRC, STAD
HTR1E P28566 HTR1E 5-hydroxytryptamine receptor 1E chr6 Not Cancer Driver No 139-150 12 8.34e-03 0.0 14 10.37 135 - SKCM, PRAD, READ, LGG, STAD, GBM, UCEC
IFITM1_ENST00000528780 P13164 IFITM1 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 20-30 11 8.34e-03 100.0 8 42.11 19 CESC COAD, GBM, PRAD, OV, CESC
OR10A4 Q9H209 OR10A4 Olfactory receptor 10A4 chr11 Not Cancer Driver No 234-244 11 8.35e-03 0.0 13 15.29 85 LUAD, LUSC PRAD, STAD, HNSC, LUAD, LUSC
TCF7_ENST00000518915 P36402-2 TCF7 Isoform 4S of Transcription factor 7 chr5 Not Cancer Driver No 10-55 46 8.35e-03 100.0 16 43.24 37 SKCM BLCA, HNSC, UCEC, LIHC, LUAD, KIRC, SKCM
SIGLEC14 Q08ET2 SIGLEC14 Sialic acid-binding Ig-like lectin 14 chr19 Not Cancer Driver No 288-296 9 8.37e-03 22.22 9 12.33 73 SKCM UCEC, LGG, SKCM
BAZ2B Q9UIF8 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B chr2 Not Cancer Driver No 589-630 42 8.37e-03 100.0 16 5.42 295 - KIRC, BRCA, HNSC, CESC, LUSC, LUAD, SKCM, BLCA, STAD
GRIA2_ENST00000264426 P42262 GRIA2 Glutamate receptor 2 chr4 Not Cancer Driver No 312-326 15 8.38e-03 0.0 16 5.48 292 HNSC, SKCM LIHC, UCEC, HNSC, PRAD, READ, SKCM, LUAD
ZNF628 Q5EBL2 ZNF628 Zinc finger protein 628 chr19 Not Cancer Driver No 831-864 34 8.39e-03 100.0 12 12.5 96 OV LIHC, STAD, LUAD, BLCA, SKCM, OV, UCEC
PCDHA10 Q9Y5I2 PCDHA10 Protocadherin alpha-10 chr5 Not Cancer Driver No 426-440 15 8.39e-03 0.0 20 6.99 286 BLCA STAD, OV, BRCA, BLCA, LUAD, SKCM, COAD, READ
CFAP47 Q6ZTR5 CFAP47 Cilia- and flagella-associated protein 47 chrX Not Cancer Driver No 827-890 64 8.40e-03 100.0 25 5.67 441 SKCM BRCA, READ, GBM, LUAD, SKCM, UCEC, LUSC, LGG
HHLA2_ENST00000489514 Q9UM44 HHLA2 HERV-H LTR-associating protein 2 chr3 Not Cancer Driver No 110-117 8 8.40e-03 0.0 10 11.63 86 SKCM HNSC, SKCM
PAF1 Q8N7H5 PAF1 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 70-74 5 8.40e-03 100.0 9 11.69 77 GBM KIRC, GBM
PNLIPRP1_ENST00000358834 P54315 PNLIPRP1 Inactive pancreatic lipase-related protein 1 chr10 Not Cancer Driver No 135-149 15 8.42e-03 0.0 11 11.96 92 LUSC, GBM HNSC, BRCA, LUSC, BLCA, GBM
HAGHL_ENST00000341413 Q6PII5 HAGHL Hydroxyacylglutathione hydrolase-like protein chr16 Not Cancer Driver No 24-30 7 8.43e-03 0.0 6 35.29 17 COAD, LUAD COAD, STAD, BRCA, LUAD
OR2G3 Q8NGZ4 OR2G3 Olfactory receptor 2G3 chr1 Not Cancer Driver No 83-122 40 8.43e-03 0.0 32 22.22 144 SKCM STAD, LUAD, PAAD, LUSC, LIHC, CESC, SKCM, UCEC, KIRC, BRCA, OV
TMED4 Q7Z7H5 TMED4 Transmembrane emp24 domain-containing protein 4 chr7 Not Cancer Driver No 159-162 4 8.43e-03 0.0 4 20.0 20 SKCM, GBM LUSC, SKCM, GBM
CROCC Q5TZA2 CROCC Rootletin chr1 Not Cancer Driver No 1007-1034 28 8.44e-03 28.57 7 2.67 262 COAD UCEC, SKCM, PRAD, LUSC, LUAD, COAD, CESC
SERPINB6_ENST00000644388 P35237 SERPINB6 Serpin B6 chr6 Not Cancer Driver No 347-376 30 8.45e-03 0.0 14 29.79 47 SKCM LUAD, COAD, BLCA, LUSC, STAD, SKCM, HNSC
ALDH1A2 O94788 ALDH1A2 Retinal dehydrogenase 2 chr15 Not Cancer Driver No 16-31 16 8.46e-03 56.25 14 14.0 100 BLCA BLCA, HNSC, LUSC, STAD, UCEC, CESC, BRCA
EFCAB12_ENST00000326085 Q6NXP0 EFCAB12 EF-hand calcium-binding domain-containing protein 12 chr3 Not Cancer Driver No 57-74 18 8.46e-03 100.0 13 13.4 97 - LUAD, CESC, HNSC, SKCM, LAML, BLCA
SPTBN5 Q9NRC6 SPTBN5 Spectrin beta chain, non-erythrocytic 5 chr15 Not Cancer Driver No 1129-1177 49 8.46e-03 100.0 8 2.45 326 BLCA KIRC, LUAD, BLCA, LGG, HNSC, SKCM
FBLN7 Q53RD9 FBLN7 Fibulin-7 chr2 Not Cancer Driver No 311-320 10 8.47e-03 0.0 9 11.25 80 - BLCA, UCEC, LIHC, SKCM, STAD, COAD, LUSC
SORCS2 Q96PQ0 SORCS2 VPS10 domain-containing receptor SorCS2 chr4 Not Cancer Driver No 828-861 34 8.49e-03 0.0 13 9.29 140 SKCM BLCA, SKCM, STAD, LUSC, LUAD, UCEC, BRCA, PRAD
TRAT1 Q6PIZ9 TRAT1 T-cell receptor-associated transmembrane adapter 1 chr3 Not Cancer Driver No 73-76 4 8.51e-03 100.0 9 10.34 87 SKCM HNSC, SKCM
SPTBN4_ENST00000598249 Q9H254 SPTBN4 Spectrin beta chain, non-erythrocytic 4 chr19 Not Cancer Driver No 237-281 45 8.53e-03 0.0 17 5.4 315 SKCM LUAD, SKCM, STAD, OV, LUSC, LGG, BRCA, BLCA, CESC
SHC4 Q6S5L8 SHC4 SHC-transforming protein 4 chr15 Not Cancer Driver No 358-398 41 8.53e-03 100.0 14 18.42 76 - LAML, LIHC, LUAD, LGG, STAD, LUSC, BRCA, HNSC, BLCA
ATXN2_ENST00000550104 Q99700 ATXN2 Ataxin-2 chr12 Not Cancer Driver No 645-682 38 8.53e-03 100.0 13 8.9 146 SKCM HNSC, BLCA, SKCM, LUSC, LIHC, KIRC, BRCA, LUAD, THCA
UGGT1 Q9NYU2 UGGT1 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 129-167 39 8.53e-03 0.0 14 8.24 170 - BLCA, GBM, KIRC, SKCM, LUAD, HNSC, UCEC, CESC
GIMAP7 Q8NHV1 GIMAP7 GTPase IMAP family member 7 chr7 Not Cancer Driver No 3-12 10 8.53e-03 27.27 11 12.22 90 UCEC UCEC, LUAD, SKCM, GBM, BRCA, STAD, CESC, LUSC, COAD
CFAP54 Q96N23 CFAP54 Cilia- and flagella-associated protein 54 chr12 Not Cancer Driver No 1865-1908 44 8.53e-03 100.0 19 5.62 338 SKCM LUSC, STAD, BRCA, CESC, LUAD, HNSC, COAD, UCEC, GBM, SKCM
CFAP54 Q96N23 CFAP54 Cilia- and flagella-associated protein 54 chr12 Not Cancer Driver No 2703-2754 52 8.53e-03 100.0 16 4.73 338 COAD, LUAD STAD, SKCM, COAD, UCEC, HNSC, LUAD
CHRNA3 P32297 CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 chr15 Not Cancer Driver No 105-113 9 8.54e-03 0.0 9 10.47 86 SKCM, STAD SKCM, STAD, READ, BRCA, LUAD
OR4X2 Q8NGF9 OR4X2 Olfactory receptor 4X2 chr11 Not Cancer Driver No 195-200 6 8.54e-03 0.0 9 10.47 86 SKCM UCEC, COAD, LUSC, SKCM
OR6C6 A6NF89 OR6C6 Olfactory receptor 6C6 chr12 Not Cancer Driver No 240-243 4 8.54e-03 0.0 9 10.84 83 SKCM BLCA, HNSC, SKCM, GBM, CESC
MYO16_ENST00000357550 Q9Y6X6 MYO16 Unconventional myosin-XVI chr13 Not Cancer Driver No 43-97 55 8.54e-03 29.09 25 6.05 413 - BRCA, OV, COAD, STAD, KIRC, UCEC, CESC, LUSC, HNSC, SKCM, LUAD
LRRC7 Q96NW7 LRRC7 Leucine-rich repeat-containing protein 7 chr1 Not Cancer Driver No 1117-1160 44 8.55e-03 100.0 29 6.09 476 - READ, STAD, UCEC, LUAD, COAD, BRCA, CESC, BLCA, SKCM, HNSC, LUSC, LAML
SCAPER Q9BY12 SCAPER S phase cyclin A-associated protein in the endoplasmic reticulum chr15 Not Cancer Driver No 204-242 39 8.56e-03 100.0 13 6.84 190 - BRCA, LGG, OV, SKCM, STAD, HNSC, READ, LIHC, LUSC
UGT2A3 Q6UWM9 UGT2A3 UDP-glucuronosyltransferase 2A3 chr4 Not Cancer Driver No 257-269 13 8.56e-03 0.0 13 8.61 151 SKCM BRCA, LUAD, SARC, BLCA, KIRC, SKCM, UCEC
ASB5 Q8WWX0 ASB5 Ankyrin repeat and SOCS box protein 5 chr4 Not Cancer Driver No 196-204 9 8.57e-03 0.0 12 10.81 111 SKCM STAD, LUSC, SKCM, LUAD, COAD
RGS4_ENST00000367909 P49798 RGS4 Regulator of G-protein signaling 4 chr1 Not Cancer Driver No 150-167 18 8.57e-03 0.0 17 25.0 68 - LUAD, HNSC, UCEC, BRCA, BLCA, GBM, STAD, SKCM, COAD, LIHC, OV
SNAPC4 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 chr9 Not Cancer Driver No 939-979 41 8.58e-03 100.0 15 10.2 147 SKCM STAD, SKCM, UCEC, CESC, HNSC
MUC16 Q8WXI7 MUC16 Mucin-16 chr19 Census Yes 986-1000 15 8.58e-03 100.0 7 0.17 4204 SKCM, OV LUAD, SKCM, LUSC, OV, HNSC
MASP2 O00187 MASP2 Mannan-binding lectin serine protease 2 chr1 Not Cancer Driver No 120-176 57 8.59e-03 0.0 22 21.78 101 SKCM UCEC, HNSC, GBM, SKCM, BLCA, BRCA, COAD, OV, STAD, LUAD
SNPH_ENST00000381873 O15079 SNPH Syntaphilin chr20 Not Cancer Driver No 18-27 10 8.60e-03 100.0 10 12.66 79 - GBM, LUSC, READ, PRAD, OV, PAAD, STAD
PSPC1_ENST00000619300 Q8WXF1 PSPC1 Paraspeckle component 1 chr13 Not Cancer Driver No 469-480 12 8.60e-03 100.0 11 11.34 97 UCEC, SKCM UCEC, SKCM, LIHC, HNSC, BRCA
FTMT Q8N4E7 FTMT Ferritin, mitochondrial chr5 Not Cancer Driver No 15-31 17 8.61e-03 100.0 18 18.75 96 - SKCM, COAD, LUSC, GBM, UCEC, STAD, SARC, PRAD, LUAD
NLRP3_ENST00000391828 Q96P20 NLRP3 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 541-554 14 8.62e-03 85.71 16 4.69 341 SKCM SKCM, LUSC, LUAD, HNSC, CESC, COAD
AADACL4 Q5VUY2 AADACL4 Arylacetamide deacetylase-like 4 chr1 Not Cancer Driver No 264-266 3 8.63e-03 0.0 11 12.09 91 GBM BLCA, LGG, COAD, PRAD, LUAD, GBM
KRTAP10-5 P60370 KRTAP10-5 Keratin-associated protein 10-5 chr21 Not Cancer Driver No 224-228 5 8.63e-03 100.0 9 11.11 81 - HNSC, LGG, STAD, CESC, BRCA, LUSC, LUAD
OR52M1 Q8NGK5 OR52M1 Olfactory receptor 52M1 chr11 Not Cancer Driver No 121-126 6 8.63e-03 0.0 10 10.75 93 SKCM LGG, GBM, LUAD, DLBC, OV, CESC, SKCM
EPHB3 P54753 EPHB3 Ephrin type-B receptor 3 chr3 Not Cancer Driver No 785-813 29 8.63e-03 51.72 14 8.97 156 SKCM PAAD, LUAD, STAD, LUSC, UCEC, SKCM
OR10H2 O60403 OR10H2 Olfactory receptor 10H2 chr19 Not Cancer Driver No 117-122 6 8.66e-03 0.0 10 10.64 94 UCEC THCA, LUSC, UCEC, PAAD, COAD, SKCM, OV
CACHD1 Q5VU97 CACHD1 VWFA and cache domain-containing protein 1 chr1 Not Cancer Driver No 1089-1120 32 8.66e-03 27.27 14 8.05 174 - OV, KICH, LUSC, STAD, BLCA, LUAD, CESC, LIHC, COAD
MAML1 Q92585 MAML1 Mastermind-like protein 1 chr5 Not Cancer Driver No 205-235 31 8.66e-03 100.0 12 11.76 102 LUAD LUAD, LGG, SKCM, GBM, LUSC, KIRC, BLCA, READ
ZDBF2 Q9HCK1 ZDBF2 DBF4-type zinc finger-containing protein 2 chr2 Not Cancer Driver No 310-317 8 8.67e-03 100.0 4 0.78 510 SKCM, COAD SKCM, BLCA, COAD
CERS1_ENST00000623882 P27544 CERS1 Ceramide synthase 1 chr19 Not Cancer Driver No 140-174 35 8.67e-03 0.0 11 37.93 29 - THCA, UCEC, KIRC, CESC, BRCA, LUSC, SKCM
IGFBP2 P18065 IGFBP2 Insulin-like growth factor-binding protein 2 chr2 Not Cancer Driver No 278-308 31 8.67e-03 38.71 10 31.25 32 - SKCM, KIRC, STAD, UCEC, READ, LUAD, LUSC
MRPL54 Q6P161 MRPL54 39S ribosomal protein L54, mitochondrial chr19 Not Cancer Driver No 85-95 11 8.67e-03 0.0 10 40.0 25 GBM SKCM, KIRC, GBM
LCE3D Q9BYE3 LCE3D Late cornified envelope protein 3D chr1 Not Cancer Driver No 59-65 7 8.68e-03 100.0 12 31.58 38 BRCA UCEC, LUAD, READ, BRCA, LIHC, BLCA, STAD, SKCM, LUSC
ALLC Q8N6M5 ALLC Probable inactive allantoicase chr2 Not Cancer Driver No 77-83 7 8.68e-03 0.0 9 9.68 93 GBM KIRC, LUAD, READ, HNSC, UCEC, GBM
ATP1A1_ENST00000295598 P05023 ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 310-341 32 8.69e-03 0.0 12 10.43 115 - THCA, BLCA, KIRC, UCEC, LIHC, STAD, SKCM, COAD
ZBTB22_ENST00000418724 O15209 ZBTB22 Zinc finger and BTB domain-containing protein 22 chr6 Not Cancer Driver No 405-421 17 8.69e-03 100.0 11 12.09 91 HNSC, SKCM HNSC, SKCM, UCEC, BLCA, LUSC
ZNF461 Q8TAF7 ZNF461 Zinc finger protein 461 chr19 Not Cancer Driver No 290-299 10 8.71e-03 0.0 9 9.57 94 UCEC BRCA, SKCM, LIHC, LUSC, UCEC
ZNF48 Q96MX3 ZNF48 Zinc finger protein 48 chr16 Not Cancer Driver No 234-243 10 8.71e-03 90.0 9 10.11 89 - LUSC, COAD, LUAD, HNSC, UCEC, SKCM
GBA2 Q9HCG7 GBA2 Non-lysosomal glucosylceramidase chr9 Not Cancer Driver No 196-210 15 8.74e-03 0.0 10 10.42 96 - SKCM, LUSC, HNSC, LUAD, OV, COAD, STAD
KRT25 Q7Z3Z0 KRT25 Keratin, type I cytoskeletal 25 chr17 Not Cancer Driver No 336-344 9 8.74e-03 0.0 10 10.2 98 - DLBC, STAD, LUAD, UCEC, BLCA, PRAD, LGG
KCNB2 Q92953 KCNB2 Potassium voltage-gated channel subfamily B member 2 chr8 Not Cancer Driver No 13-23 11 8.74e-03 90.91 15 4.02 373 SKCM LGG, LUAD, HNSC, READ, LUSC, SKCM, SARC
SYCE1_ENST00000343131 Q8N0S2 SYCE1 Synaptonemal complex central element protein 1 chr10 Not Cancer Driver No 224-260 37 8.75e-03 23.68 18 25.35 71 SKCM LUAD, BLCA, UCEC, PRAD, LUSC, SKCM, READ, OV, HNSC
AVPR1A P37288 AVPR1A Vasopressin V1a receptor chr12 Not Cancer Driver No 248-259 12 8.75e-03 58.33 13 12.26 106 LUAD COAD, LUAD, READ, GBM, PAAD, LGG, HNSC, BRCA, LUSC
MED24_ENST00000394128 O75448 MED24 Mediator of RNA polymerase II transcription subunit 24 chr17 Not Cancer Driver No 617-644 28 8.75e-03 0.0 11 10.78 102 BRCA KIRC, UCEC, OV, CESC, LIHC, STAD, BRCA, COAD
PCSK9 Q8NBP7 PCSK9 Proprotein convertase subtilisin/kexin type 9 chr1 Not Cancer Driver No 162-173 12 8.76e-03 100.0 10 11.63 86 OV LUSC, LUAD, KIRC, OV, SKCM
SLC4A4_ENST00000264485 Q9Y6R1 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 chr4 Not Cancer Driver No 398-441 44 8.77e-03 90.91 26 13.4 194 SKCM STAD, LUSC, HNSC, SKCM, GBM, KIRC, BRCA, BLCA, OV
PNISR_ENST00000438806 Q8TF01 PNISR Arginine/serine-rich protein PNISR chr6 Not Cancer Driver No 206-254 49 8.77e-03 83.67 23 19.83 116 - LIHC, HNSC, OV, STAD, SKCM, LUSC, UCEC, GBM, BLCA
OR51F1 A6NGY5 OR51F1 Olfactory receptor 51F1 chr11 Not Cancer Driver No 165-172 8 8.78e-03 0.0 12 11.65 103 COAD LUSC, STAD, SKCM, OV, LUAD, COAD
PARP9 Q8IXQ6 PARP9 Protein mono-ADP-ribosyltransferase PARP9 chr3 Not Cancer Driver No 426-448 23 8.78e-03 0.0 13 11.71 111 SKCM BLCA, COAD, LUAD, LUSC, CESC, SKCM
GPR45 Q9Y5Y3 GPR45 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 61-66 6 8.79e-03 0.0 9 9.18 98 STAD BLCA, LUAD, HNSC, STAD, SARC
RTL5 Q5HYW3 RTL5 Retrotransposon Gag-like protein 5 chrX Not Cancer Driver No 109-118 10 8.79e-03 100.0 9 8.82 102 LUAD HNSC, UCEC, SKCM, COAD, LUAD
EMP2_ENST00000536829 P54851 EMP2 Epithelial membrane protein 2 chr16 Not Cancer Driver No 99-132 34 8.80e-03 0.0 12 50.0 24 - GBM, KIRC, LIHC, UCEC, BLCA, STAD, LUAD, COAD, LUSC, SKCM
DMRTB1 Q96MA1 DMRTB1 Doublesex- and mab-3-related transcription factor B1 chr1 Not Cancer Driver No 202-253 52 8.80e-03 100.0 21 33.87 62 SKCM COAD, LUAD, BLCA, GBM, STAD, THCA, SKCM, KIRC
PIK3R2_ENST00000617130 O00459 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 557-571 15 8.81e-03 0.0 11 11.34 97 UCEC STAD, PRAD, HNSC, KIRC, LUSC, UCEC
LRCH1_ENST00000389798 Q9Y2L9 LRCH1 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 Not Cancer Driver No 357-370 14 8.81e-03 100.0 9 9.38 96 - OV, PAAD, HNSC, READ, LUSC, COAD
SPRTN Q9H040 SPRTN DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 140-181 42 8.81e-03 0.0 17 22.97 74 UCEC, BRCA UCEC, KIRC, STAD, OV, LUAD, READ, BRCA, CESC
ZBED2 Q9BTP6 ZBED2 Zinc finger BED domain-containing protein 2 chr3 Not Cancer Driver No 149-166 18 8.81e-03 0.0 17 27.42 62 SKCM SKCM, LIHC, STAD, LUSC
FERMT3 Q86UX7 FERMT3 Fermitin family homolog 3 chr11 Not Cancer Driver No 179-190 12 8.84e-03 100.0 9 9.09 99 - UCEC, KIRC, BLCA, SKCM, LUAD
TRIM56 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 chr7 Not Cancer Driver No 503-512 10 8.84e-03 0.0 9 7.89 114 - BRCA, HNSC, KIRC, OV, LUAD, STAD, LGG
EEF1AKMT2 Q5JPI9 EEF1AKMT2 EEF1A lysine methyltransferase 2 chr10 Not Cancer Driver No 8-8 1 8.84e-03 100.0 14 48.28 29 READ, COAD READ, OAD, COAD
PHF5A Q7RTV0 PHF5A PHD finger-like domain-containing protein 5A chr22 Not Cancer Driver No 55-57 3 8.84e-03 0.0 7 35.0 20 LGG, GBM LUSC, LGG, GBM, STAD
SYTL4 Q96C24 SYTL4 Synaptotagmin-like protein 4 chrX Not Cancer Driver No 61-72 12 8.84e-03 8.33 13 11.21 116 SKCM UCEC, GBM, COAD, SKCM, LUAD, LUSC
SLC35G2 Q8TBE7 SLC35G2 Solute carrier family 35 member G2 chr3 Not Cancer Driver No 65-72 8 8.85e-03 100.0 4 9.52 42 OV READ, LUSC, OV
ICMT O60725 ICMT Protein-S-isoprenylcysteine O-methyltransferase chr1 Not Cancer Driver No 234-274 41 8.85e-03 0.0 10 41.67 24 UCEC SKCM, KIRC, COAD, PRAD, UCEC, LGG
ADAMTS17 Q8TE56 ADAMTS17 A disintegrin and metalloproteinase with thrombospondin motifs 17 chr15 Not Cancer Driver No 859-884 26 8.87e-03 15.38 13 7.1 183 SKCM HNSC, UCEC, LAML, SKCM, OV, CESC, LUAD
KCNA1 Q09470 KCNA1 Potassium voltage-gated channel subfamily A member 1 chr12 Not Cancer Driver No 6-15 10 8.87e-03 100.0 14 7.95 176 CESC UCEC, CESC, PRAD, BLCA, LUAD, OV
ACVRL1 P37023 ACVRL1 Serine/threonine-protein kinase receptor R3 chr12 Not Cancer Driver No 379-387 9 8.88e-03 0.0 9 9.57 94 - COAD, SKCM, CESC, LIHC, HNSC, READ, UCEC
ZXDB P98169 ZXDB Zinc finger X-linked protein ZXDB chrX Compendium Yes 412-422 11 8.88e-03 63.64 10 10.31 97 UCEC SKCM, OV, LUSC, COAD, UCEC
EN2 P19622 EN2 Homeobox protein engrailed-2 chr7 Not Cancer Driver No 225-249 25 8.88e-03 100.0 11 45.83 24 SKCM, STAD SKCM, GBM, COAD, STAD, OV
FAM181B A6NEQ2 FAM181B Protein FAM181B chr11 Not Cancer Driver No 48-77 30 8.88e-03 36.67 9 34.62 26 CESC, BLCA CESC, SKCM, BLCA, STAD, DLBC
SPAG8_ENST00000396638 Q99932 SPAG8 Sperm-associated antigen 8 chr9 Not Cancer Driver No 179-192 14 8.88e-03 100.0 4 8.33 48 READ PRAD, READ, KIRC, LIHC
VCX3A Q9NNX9 VCX3A Variable charge X-linked protein 3 chrX Not Cancer Driver No 171-182 12 8.88e-03 100.0 8 30.77 26 STAD READ, CESC, LGG, SKCM, STAD, BRCA
GUCY1A1_ENST00000513574 Q02108 GUCY1A1 Guanylate cyclase soluble subunit alpha-1 chr4 Not Cancer Driver No 304-319 16 8.92e-03 37.5 14 7.65 183 SKCM HNSC, BLCA, LUSC, LUAD, CESC, SKCM, UCEC
WDR27 A2RRH5-4 WDR27 Isoform 4 of WD repeat-containing protein 27 chr6 Not Cancer Driver No 461-476 16 8.93e-03 100.0 9 8.74 103 SKCM UCEC, HNSC, SKCM, KIRC, LUSC
USP8 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 chr15 Census, Compendium Yes 696-720 25 8.94e-03 100.0 11 9.02 122 SKCM SKCM, LUAD, READ, BLCA, STAD, BRCA, CESC, LIHC
CFAP100 Q494V2 CFAP100 Cilia- and flagella-associated protein 100 chr3 Not Cancer Driver No 557-567 11 8.95e-03 0.0 10 8.55 117 - UCEC, STAD, LUAD, OV, SKCM, READ, LUSC
SPERT Q8NA61 CBY2 Protein chibby homolog 2 chr13 Not Cancer Driver No 250-257 8 8.95e-03 0.0 9 7.96 113 SKCM SKCM, OV, READ, UCEC
KCNF1 Q9H3M0 KCNF1 Potassium voltage-gated channel subfamily F member 1 chr2 Not Cancer Driver No 156-168 13 8.97e-03 28.57 12 10.17 118 BLCA, LUAD HNSC, BLCA, BRCA, STAD, CESC, LUAD, LUSC
PGLYRP2 Q96PD5 PGLYRP2 N-acetylmuramoyl-L-alanine amidase chr19 Not Cancer Driver No 387-397 11 8.97e-03 0.0 13 10.83 120 SKCM SKCM, THCA, COAD, BRCA, STAD, PRAD, LUSC, READ
IL1RL2 Q9HB29 IL1RL2 Interleukin-1 receptor-like 2 chr2 Not Cancer Driver No 82-90 9 8.97e-03 0.0 9 7.83 115 SKCM KIRC, HNSC, SARC, SKCM
TMEM200A Q86VY9 TMEM200A Transmembrane protein 200A chr6 Not Cancer Driver No 341-358 18 8.98e-03 100.0 19 9.74 195 SKCM STAD, OV, LUSC, LUAD, SKCM, UCEC, HNSC, BRCA, BLCA, GBM
CHRND Q07001 CHRND Acetylcholine receptor subunit delta chr2 Not Cancer Driver No 418-425 8 8.99e-03 100.0 9 8.18 110 LUAD LUAD, SKCM, HNSC, UCEC, THCA, STAD
STRIP2 Q9ULQ0 STRIP2 Striatin-interacting protein 2 chr7 Not Cancer Driver No 737-747 11 8.99e-03 0.0 14 12.17 115 - COAD, LUSC, LIHC, SKCM, LUAD, STAD
PTPRT_ENST00000373187 O14522 PTPRT Receptor-type tyrosine-protein phosphatase T chr20 Census, Compendium Yes 827-839 13 9.01e-03 100.0 17 3.16 538 SKCM LUAD, LUSC, SKCM, STAD, COAD, UCEC
MLXIPL Q9NP71 MLXIPL Carbohydrate-responsive element-binding protein chr7 Not Cancer Driver No 805-816 12 9.01e-03 0.0 9 8.18 110 STAD STAD, LUSC, LIHC, SKCM, LUAD, BRCA
RHPN2 Q8IUC4 RHPN2 Rhophilin-2 chr19 Compendium Yes 351-360 10 9.01e-03 0.0 9 8.04 112 - LGG, READ, THCA, HNSC, SKCM, COAD
C9orf72 Q96LT7 C9orf72 Guanine nucleotide exchange factor C9orf72 chr9 Not Cancer Driver No 67-76 10 9.01e-03 10.0 7 10.94 64 OV READ, KIRC, SKCM, STAD, OV
VANGL2 Q9ULK5 VANGL2 Vang-like protein 2 chr1 Not Cancer Driver No 15-27 13 9.02e-03 100.0 11 9.02 122 UCEC READ, LUSC, GBM, STAD, LGG, UCEC, BRCA
CES1_ENST00000361503 P23141 CES1 Liver carboxylesterase 1 chr16 Not Cancer Driver No 134-200 67 9.02e-03 0.0 34 24.46 139 SKCM OV, KIRC, LUAD, SKCM, GBM, BLCA, BRCA, STAD, CESC, UCEC, THCA
FBN2_ENST00000262464 P35556 FBN2 Fibrillin-2 chr5 Compendium Yes 1411-1435 25 9.03e-03 100.0 16 2.63 608 LUAD, SKCM BRCA, LUAD, BLCA, THCA, LIHC, UCEC, HNSC, SKCM
ZNF711_ENST00000373165 Q9Y462 ZNF711 Zinc finger protein 711 chrX Not Cancer Driver No 611-626 16 9.04e-03 0.0 13 6.77 192 SKCM KIRC, LUAD, OV, HNSC, BRCA, CESC, SKCM
C14orf39 Q8N1H7 SIX6OS1 Protein SIX6OS1 chr14 Not Cancer Driver No 463-470 8 9.05e-03 100.0 9 6.98 129 SKCM CESC, HNSC, SKCM, LIHC
SPHKAP Q2M3C7 SPHKAP A-kinase anchor protein SPHKAP chr2 Not Cancer Driver No 1133-1145 13 9.07e-03 46.15 15 2.38 630 SKCM HNSC, SKCM, KIRC, LUSC, BRCA, STAD, BLCA, LUAD
DNAH17 Q9UFH2 DNAH17 Dynein axonemal heavy chain 17 chr17 Not Cancer Driver No 3224-3259 36 9.08e-03 100.0 15 2.02 744 COAD LUAD, KIRC, UCEC, SKCM, COAD, PAAD, STAD, OV
ZNF81 P51508 ZNF81 Zinc finger protein 81 chrX Not Cancer Driver No 476-485 10 9.08e-03 0.0 10 8.13 123 - KIRC, STAD, SKCM, HNSC, LUAD
IVL P07476 IVL Involucrin chr1 Not Cancer Driver No 139-153 15 9.08e-03 100.0 12 10.08 119 STAD, SKCM LUSC, STAD, OV, SKCM, KIRC, COAD
KIF1C O43896 KIF1C Kinesin-like protein KIF1C chr17 Not Cancer Driver No 889-915 27 9.08e-03 100.0 13 9.92 131 SKCM OAD, STAD, HNSC, BLCA, SKCM
RYR1 P21817 RYR1 Ryanodine receptor 1 chr19 Not Cancer Driver No 806-850 45 9.09e-03 100.0 22 2.18 1011 LUSC, SKCM BRCA, BLCA, KIRC, LUSC, LUAD, COAD, SKCM, UCEC
AMER2 Q8N7J2 AMER2 APC membrane recruitment protein 2 chr13 Not Cancer Driver No 638-647 10 9.10e-03 100.0 11 9.32 118 - OV, SKCM, LUAD, LAML, HNSC, COAD
CBX4 O00257 CBX4 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 504-509 6 9.10e-03 100.0 4 4.94 81 COAD, READ STAD, COAD, READ, GBM
ACPP_ENST00000336375 P15309 ACP3 Prostatic acid phosphatase chr3 Not Cancer Driver No 334-340 7 9.10e-03 0.0 4 4.88 82 OV LIHC, OV, UCEC, BLCA
CPXM2 Q8N436 CPXM2 Inactive carboxypeptidase-like protein X2 chr10 Not Cancer Driver No 670-684 15 9.11e-03 0.0 13 6.53 199 LUAD STAD, READ, GBM, SKCM, LUAD, LUSC, BLCA, OV
ACTC1 P68032 ACTC1 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 313-318 6 9.12e-03 0.0 9 7.89 114 SKCM LUSC, BLCA, SKCM
KCNN2 Q9H2S1 KCNN2 Small conductance calcium-activated potassium channel protein 2 chr5 Not Cancer Driver No 557-565 9 9.12e-03 100.0 10 8.93 112 - STAD, UCEC, BRCA, SKCM, LUSC, HNSC, COAD
PDE4B Q07343 PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 Not Cancer Driver No 542-552 11 9.12e-03 0.0 10 8.26 121 UCEC HNSC, BLCA, SKCM, LUAD, UCEC
HIST1H3C P68431 H3C12 Histone H3.1 chr6 Not Cancer Driver No 30-41 12 9.12e-03 100.0 13 28.89 45 HNSC HNSC, SKCM, LUAD, BLCA, BRCA
ADGRB2_ENST00000373658 O60241 ADGRB2 Adhesion G protein-coupled receptor B2 chr1 Not Cancer Driver No 203-239 37 9.12e-03 83.78 15 7.28 206 SKCM UCEC, PRAD, STAD, LUAD, GBM, SKCM, COAD, KIRC
ILDR1_ENST00000344209 Q86SU0 ILDR1 Immunoglobulin-like domain-containing receptor 1 chr3 Not Cancer Driver No 358-367 10 9.13e-03 100.0 13 11.5 113 SKCM SKCM, BRCA
YTHDC1_ENST00000344157 Q96MU7 YTHDC1 YTH domain-containing protein 1 chr4 Not Cancer Driver No 669-683 15 9.13e-03 100.0 11 8.03 137 - BRCA, CESC, LUAD, LUSC, SKCM, LGG, HNSC, READ, STAD, UCEC
AHRR_ENST00000505113 A9YTQ3 AHRR Aryl hydrocarbon receptor repressor chr5 Not Cancer Driver No 258-267 10 9.13e-03 0.0 12 10.08 119 SKCM STAD, SKCM, LUSC, BRCA, COAD, HNSC, PRAD
MLLT10_ENST00000377059 P55197 MLLT10 Protein AF-10 chr10 Census Yes 682-688 7 9.13e-03 100.0 9 6.77 133 BRCA BRCA, SKCM, LUSC, UCEC, READ, LUAD
ZNF534 Q76KX8 ZNF534 Zinc finger protein 534 chr19 Not Cancer Driver No 305-310 6 9.13e-03 0.0 9 6.52 138 SKCM BLCA, HNSC, SKCM
PPP1R15A O75807 PPP1R15A Protein phosphatase 1 regulatory subunit 15A chr19 Not Cancer Driver No 640-646 7 9.14e-03 100.0 4 4.35 92 UCEC, KIRC UCEC, BLCA, KIRC
TREML2 Q5T2D2 TREML2 Trem-like transcript 2 protein chr6 Not Cancer Driver No 39-69 31 9.15e-03 12.9 17 25.37 67 - GBM, STAD, HNSC, OV, COAD, UCEC, READ, BLCA, SKCM
CRISPLD1 Q9H336 CRISPLD1 Cysteine-rich secretory protein LCCL domain-containing 1 chr8 Not Cancer Driver No 217-222 6 9.15e-03 0.0 10 8.7 115 - COAD, LUAD, LUSC, STAD, BRCA, KIRC, READ
GPRIN1 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 chr5 Not Cancer Driver No 386-396 11 9.15e-03 100.0 9 7.76 116 STAD LUSC, READ, STAD, KIRC, UCEC, LIHC, SKCM
RALYL_ENST00000521268 Q86SE5 RALYL RNA-binding Raly-like protein chr8 Not Cancer Driver No 145-159 15 9.15e-03 100.0 17 15.32 111 - HNSC, UCEC, SKCM, COAD, LGG, BRCA, BLCA, LUAD, STAD, GBM
FOXG1 P55316 FOXG1 Forkhead box protein G1 chr14 Not Cancer Driver No 267-278 12 9.17e-03 100.0 13 9.85 132 STAD STAD, LUAD, SKCM, UCEC
MST1 P26927 MST1 Hepatocyte growth factor-like protein chr3 Not Cancer Driver No 365-374 10 9.17e-03 40.0 9 7.96 113 LGG LGG, GBM, UCEC, CESC, LUSC, STAD, LUAD
CYP7B1 O75881 CYP7B1 Cytochrome P450 7B1 chr8 Not Cancer Driver No 332-338 7 9.18e-03 0.0 9 6.72 134 SKCM, STAD SKCM, STAD
NR5A2 O00482 NR5A2 Nuclear receptor subfamily 5 group A member 2 chr1 Not Cancer Driver No 433-439 7 9.18e-03 0.0 10 7.87 127 SKCM GBM, SKCM, CESC, COAD, STAD
PRPF4B Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog chr6 Not Cancer Driver No 301-314 14 9.19e-03 100.0 4 3.33 120 BLCA BLCA, HNSC, SKCM, LUSC
TLE1 Q04724 TLE1 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 638-648 11 9.19e-03 0.0 4 3.6 111 UCEC SKCM, LUSC, UCEC, PRAD
HYDIN Q4G0P3 HYDIN Hydrocephalus-inducing protein homolog chr16 Not Cancer Driver No 3302-3331 30 9.19e-03 100.0 17 1.93 881 SKCM UCEC, HNSC, BRCA, COAD, GBM, CESC, SKCM
SALL1 Q9NSC2 SALL1 Sal-like protein 1 chr16 Not Cancer Driver No 151-166 16 9.20e-03 100.0 19 4.1 463 COAD PRAD, UCEC, BRCA, LUAD, KIRC, COAD, BLCA
OR5H15 A6NDH6 OR5H15 Olfactory receptor 5H15 chr3 Not Cancer Driver No 119-122 4 9.20e-03 0.0 10 7.09 141 SKCM STAD, UCEC, KIRC, LUSC, SKCM
SLC6A17 Q9H1V8 SLC6A17 Sodium-dependent neutral amino acid transporter SLC6A17 chr1 Not Cancer Driver No 507-514 8 9.20e-03 0.0 4 3.31 121 OV LUAD, BRCA, OV, PRAD, SKCM
CDRT15 Q96T59 CDRT15 CMT1A duplicated region transcript 15 protein chr17 Not Cancer Driver No 40-44 5 9.20e-03 100.0 8 30.77 26 - SKCM, HNSC, UCEC, READ, LUAD, LUSC
SEMA6C Q9H3T2 SEMA6C Semaphorin-6C chr1 Not Cancer Driver No 466-478 13 9.21e-03 0.0 9 7.76 116 STAD LUAD, SKCM, BLCA, CESC, LUSC, STAD
LRGUK Q96M69 LRGUK Leucine-rich repeat and guanylate kinase domain-containing protein chr7 Not Cancer Driver No 541-548 8 9.23e-03 0.0 11 7.43 148 - SKCM, STAD, LUSC, HNSC, BRCA, LUAD, BLCA
SPECC1 Q5M775 SPECC1 Cytospin-B chr17 Census Yes 568-579 12 9.23e-03 100.0 5 2.98 168 COAD LIHC, COAD, HNSC, UCEC, STAD
MAP3K4 Q9Y6R4 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 chr6 Not Cancer Driver No 1170-1223 54 9.24e-03 100.0 21 7.98 263 - KIRC, CESC, BRCA, SKCM, OV, LIHC, COAD, STAD, LUAD, HNSC, READ
OR4N2_ENST00000557677 Q8NGD1 OR4N2 Olfactory receptor 4N2 chr14 Not Cancer Driver No 38-43 6 9.24e-03 0.0 14 6.86 204 SKCM STAD, SKCM, HNSC, LUAD, GBM
ZNF98 A6NK75 ZNF98 Zinc finger protein 98 chr19 Not Cancer Driver No 113-123 11 9.24e-03 100.0 15 6.41 234 - LIHC, STAD, READ, LUSC, LUAD, SKCM, COAD
CPNE4_ENST00000511604 Q96A23 CPNE4 Copine-4 chr3 Not Cancer Driver No 177-183 7 9.24e-03 0.0 11 8.09 136 SKCM UCEC, HNSC, SKCM
CCN3 P48745 CCN3 CCN family member 3 chr8 Not Cancer Driver No 91-118 28 9.25e-03 7.14 15 20.83 72 LUSC BRCA, LIHC, UCEC, LUSC, COAD, KIRC, LUAD, HNSC
OR6C74 A6NCV1 OR6C74 Olfactory receptor 6C74 chr12 Not Cancer Driver No 62-86 25 9.25e-03 0.0 28 29.47 95 SKCM LUSC, BLCA, LUAD, SKCM, COAD, LIHC
INVS Q9Y283 INVS Inversin chr9 Not Cancer Driver No 585-591 7 9.26e-03 0.0 9 7.14 126 OV SKCM, OV, CESC
KTN1 Q86UP2 KTN1 Kinectin chr14 Census Yes 679-694 16 9.26e-03 0.0 9 6.34 142 GBM BLCA, SKCM, GBM
PTPN11_ENST00000351677 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 461-468 8 9.26e-03 0.0 11 8.53 129 SKCM, UCEC LIHC, SKCM, UCEC, READ, STAD
OR2T27 Q8NH04 OR2T27 Olfactory receptor 2T27 chr1 Not Cancer Driver No 133-138 6 9.26e-03 0.0 15 11.03 136 LUAD STAD, GBM, HNSC, LUSC, CESC, LUAD, UCEC, READ
GABRB1 P18505 GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 chr4 Not Cancer Driver No 411-416 6 9.27e-03 100.0 10 7.41 135 - LUAD, SKCM, STAD, PRAD, UCEC, KIRC, LGG, LUSC
VEGFC P49767 VEGFC Vascular endothelial growth factor C chr4 Not Cancer Driver No 354-359 6 9.27e-03 0.0 10 7.81 128 SKCM BRCA, SKCM, LUAD, LUSC, BLCA
ATP7B P35670 ATP7B Copper-transporting ATPase 2 chr13 Not Cancer Driver No 515-526 12 9.27e-03 41.67 4 1.88 213 SKCM, OV SKCM, UCEC, OV, COAD
FGFR1_ENST00000447712 P11362 FGFR1 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 734-743 10 9.29e-03 0.0 10 6.58 152 - THCA, BLCA, SKCM, UCEC, OV, STAD
OR10J1 P30954 OR10J1 Olfactory receptor 10J1 chr1 Not Cancer Driver No 130-133 4 9.29e-03 0.0 10 7.25 138 BRCA LUAD, SKCM, COAD, UCEC, PRAD, BRCA
OR10X1 Q8NGY0 OR10X1 Olfactory receptor 10X1 chr1 Not Cancer Driver No 310-313 4 9.29e-03 0.0 9 7.26 124 SKCM SKCM, LUSC
PRKG2 Q13237 PRKG2 cGMP-dependent protein kinase 2 chr4 Not Cancer Driver No 141-145 5 9.29e-03 100.0 9 6.34 142 SKCM BRCA, SARC, CESC, SKCM
PCDHGC5 Q9Y5F6 PCDHGC5 Protocadherin gamma-C5 chr5 Not Cancer Driver No 744-751 8 9.30e-03 100.0 9 6.57 137 GBM COAD, GBM, LGG
RANBP6 O60518 RANBP6 Ran-binding protein 6 chr9 Not Cancer Driver No 977-984 8 9.30e-03 0.0 9 5.84 154 - GBM, LUSC, COAD, BLCA, UCEC, KIRC, LUAD
WDR36 Q8NI36 WDR36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 4-14 11 9.30e-03 100.0 10 7.14 140 - COAD, DLBC, LUAD, SKCM, OV, STAD, BLCA, READ
TLR5_ENST00000366881 O60602 TLR5 Toll-like receptor 5 chr1 Not Cancer Driver No 195-204 10 9.31e-03 0.0 9 5.96 151 - SARC, STAD, SKCM, LGG, HNSC, UCEC
LIN37 Q96GY3 LIN37 Protein lin-37 homolog chr19 Not Cancer Driver No 187-240 54 9.31e-03 27.78 15 44.12 34 - LUSC, UCEC, LUAD, KIRC, SKCM, CESC, BRCA
CSMD3 Q7Z407 CSMD3 CUB and sushi domain-containing protein 3 chr8 Census Yes 3306-3322 17 9.32e-03 100.0 22 1.21 1816 - LUAD, STAD, BRCA, COAD, BLCA, UCEC, SKCM, HNSC, PRAD, LUSC
HTR2C P28335 HTR2C 5-hydroxytryptamine receptor 2C chrX Not Cancer Driver No 163-168 6 9.33e-03 50.0 11 7.86 140 - BRCA, READ, UCEC, SKCM, PRAD, PAAD, GBM, LUSC
COL4A4 P53420 COL4A4 Collagen alpha-4(IV) chain chr2 Not Cancer Driver No 415-420 6 9.33e-03 100.0 4 0.86 465 OV, SKCM OV, SKCM, HNSC
NMUR2 Q9GZQ4 NMUR2 Neuromedin-U receptor 2 chr5 Not Cancer Driver No 160-168 9 9.33e-03 0.0 14 9.72 144 SKCM LUAD, READ, COAD, UCEC, SKCM, LUSC, KIRC
NMUR2 Q9GZQ4 NMUR2 Neuromedin-U receptor 2 chr5 Not Cancer Driver No 200-208 9 9.33e-03 0.0 12 8.33 144 SKCM LUAD, READ, SKCM, KIRC, BRCA, OV
LIPI_ENST00000536861 Q6XZB0 LIPI Lipase member I chr21 Not Cancer Driver No 235-238 4 9.34e-03 0.0 10 6.94 144 SKCM HNSC, STAD, UCEC, SKCM, LGG
ANLN Q9NQW6 ANLN Anillin chr7 Not Cancer Driver No 151-163 13 9.35e-03 84.62 9 6.08 148 - SKCM, LUAD, READ, BRCA, HNSC, GBM
OR5T1_ENST00000641368 Q8NG75 OR5T1 Olfactory receptor 5T1 chr11 Not Cancer Driver No 132-134 3 9.35e-03 0.0 10 7.52 133 SKCM LGG, PRAD, OV, UCEC, SKCM, LUSC
CD96 P40200 CD96 T-cell surface protein tactile chr3 Not Cancer Driver No 19-24 6 9.36e-03 100.0 9 6.82 132 SKCM HNSC, SKCM, PRAD
COL18A1 P39060 COL18A1 Collagen alpha-1(XVIII) chain chr21 Not Cancer Driver No 1408-1463 56 9.37e-03 82.76 12 6.45 186 COAD CESC, LUAD, READ, COAD, UCEC
AKAP13_ENST00000394518 Q12802 AKAP13 A-kinase anchor protein 13 chr15 Not Cancer Driver No 2783-2793 11 9.37e-03 100.0 8 2.19 365 BLCA SARC, UCEC, SKCM, STAD, BLCA, READ
BEX2_ENST00000372677 Q9BXY8 BEX2 Protein BEX2 chrX Not Cancer Driver No 49-58 10 9.38e-03 90.0 10 43.48 23 GBM, LUAD SKCM, GBM, STAD, LUAD, PAAD, SARC
RHBDD3 Q9Y3P4 RHBDD3 Rhomboid domain-containing protein 3 chr22 Not Cancer Driver No 207-236 30 9.38e-03 93.33 8 33.33 24 HNSC, SKCM, COAD HNSC, SKCM, UCEC, LUSC, COAD
SLC25A48 Q6ZT89-3 SLC25A48 Isoform 3 of Solute carrier family 25 member 48 chr5 Not Cancer Driver No 91-102 12 9.38e-03 100.0 8 26.67 30 STAD, SKCM, LUAD STAD, SKCM, LUAD, PAAD
GIGYF1_ENST00000646601 O75420 GIGYF1 GRB10-interacting GYF protein 1 chr7 Not Cancer Driver No 223-228 6 9.38e-03 100.0 9 6.52 138 BRCA LGG, GBM, LUSC, COAD, BRCA, HNSC, PRAD
OR51S1 Q8NGJ8 OR51S1 Olfactory receptor 51S1 chr11 Not Cancer Driver No 194-200 7 9.38e-03 0.0 15 10.71 140 SKCM SKCM, LUAD, UCEC, BLCA, STAD
PCDHB4 Q9Y5E5 PCDHB4 Protocadherin beta-4 chr5 Not Cancer Driver No 527-538 12 9.39e-03 0.0 16 6.25 256 - COAD, GBM, OV, STAD, BLCA, LGG, UCEC, LUAD, SKCM, HNSC
SV2B Q7L1I2 SV2B Synaptic vesicle glycoprotein 2B chr15 Not Cancer Driver No 15-22 8 9.39e-03 100.0 9 6.29 143 - SARC, UCEC, LUAD, BLCA, BRCA, READ, SKCM
OR2G3 Q8NGZ4 OR2G3 Olfactory receptor 2G3 chr1 Not Cancer Driver No 6-8 3 9.40e-03 100.0 11 7.64 144 LUSC, SKCM LUSC, LUAD, BLCA, SKCM
SPAG16 Q8N0X2 SPAG16 Sperm-associated antigen 16 protein chr2 Not Cancer Driver No 319-326 8 9.40e-03 100.0 10 6.21 161 SKCM LIHC, SKCM, CESC, LUAD
ARID4B Q4LE39 ARID4B AT-rich interactive domain-containing protein 4B chr1 Not Cancer Driver No 956-984 29 9.40e-03 100.0 14 9.72 144 LUSC, BLCA SKCM, GBM, LUSC, UCEC, STAD, BLCA, BRCA
PSG2 P11465 PSG2 Pregnancy-specific beta-1-glycoprotein 2 chr19 Not Cancer Driver No 263-269 7 9.40e-03 0.0 11 7.91 139 - KIRC, BLCA, SARC, LIHC, COAD, UCEC, LUSC, THCA, SKCM, HNSC
USP42 Q9H9J4 USP42 Ubiquitin carboxyl-terminal hydrolase 42 chr7 Not Cancer Driver No 427-453 27 9.40e-03 100.0 12 7.95 151 LUSC COAD, KIRC, LUSC, UCEC, SKCM, LIHC, STAD, READ
CACNA2D3_ENST00000415676 Q8IZS8 CACNA2D3 Voltage-dependent calcium channel subunit alpha-2/delta-3 chr3 Not Cancer Driver No 565-578 14 9.41e-03 0.0 18 6.84 263 SKCM STAD, LUAD, UCEC, COAD, SKCM, LUSC, HNSC
CDSN Q15517 CDSN Corneodesmosin chr6 Not Cancer Driver No 143-153 11 9.41e-03 100.0 2 3.57 56 BLCA SKCM, UCEC, BLCA
KIRREL1 Q96J84 KIRREL1 Kin of IRRE-like protein 1 chr1 Not Cancer Driver No 519-528 10 9.41e-03 50.0 10 7.09 141 - CESC, STAD, GBM, UCEC, PRAD, LUAD
MAGEA12 P43365 MAGEA12 Melanoma-associated antigen 12 chrX Not Cancer Driver No 247-250 4 9.41e-03 0.0 9 7.03 128 - BLCA, CESC, READ, LUAD, STAD
ADGRF4 Q8IZF3 ADGRF4 Adhesion G protein-coupled receptor F4 chr6 Not Cancer Driver No 428-439 12 9.42e-03 0.0 12 8.33 144 SKCM STAD, OV, LGG, SKCM, PRAD
TBC1D32 Q96NH3 TBC1D32 Protein broad-minded chr6 Not Cancer Driver No 879-905 27 9.42e-03 0.0 13 7.26 179 LUSC SKCM, UCEC, STAD, LUSC, BRCA, HNSC
DPP6 P42658 DPP6 Dipeptidyl aminopeptidase-like protein 6 chr7 Not Cancer Driver No 390-402 13 9.42e-03 0.0 13 5.28 246 LUSC LUAD, BLCA, LUSC, READ, SKCM, COAD, STAD
CEACAM5 P06731 CEACAM5 Carcinoembryonic antigen-related cell adhesion molecule 5 chr19 Not Cancer Driver No 597-607 11 9.43e-03 0.0 13 9.35 139 SKCM COAD, LIHC, SARC, KIRC, GBM, SKCM, BLCA
CRYBG3 Q68DQ2 CRYBG3 Very large A-kinase anchor protein chr3 Not Cancer Driver No 2016-2049 34 9.44e-03 100.0 10 5.52 181 - STAD, SKCM, LUSC, BLCA, BRCA, COAD, CESC, HNSC
EIF2AK3 Q9NZJ5 EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 Not Cancer Driver No 622-633 12 9.45e-03 25.0 9 6.04 149 - BLCA, LIHC, LUSC, OV, STAD, COAD, UCEC
TMEM94_ENST00000314256 Q12767 TMEM94 Transmembrane protein 94 chr17 Not Cancer Driver No 483-497 15 9.45e-03 100.0 10 6.85 146 - UCEC, BRCA, HNSC, PRAD, LUAD, STAD, SKCM, BLCA
TBC1D8_ENST00000376840 O95759 TBC1D8 TBC1 domain family member 8 chr2 Not Cancer Driver No 300-322 23 9.45e-03 0.0 14 8.14 172 - UCEC, SKCM, OV, BRCA, READ, LUSC, GBM, STAD
CAPSL Q8WWF8 CAPSL Calcyphosin-like protein chr5 Not Cancer Driver No 57-70 14 9.45e-03 0.0 18 21.69 83 SKCM BLCA, LUSC, BRCA, READ, HNSC, LUAD, SKCM
UNC5B Q8IZJ1 UNC5B Netrin receptor UNC5B chr10 Not Cancer Driver No 277-287 11 9.46e-03 0.0 9 5.73 157 - UCEC, LUSC, STAD, SKCM, OV, COAD, LUAD
KCNK9 Q9NPC2 KCNK9 Potassium channel subfamily K member 9 chr8 Not Cancer Driver No 303-310 8 9.46e-03 100.0 13 9.35 139 STAD COAD, READ, BRCA, STAD, SKCM, PRAD, BLCA
DNAH9 Q9NYC9 DNAH9 Dynein axonemal heavy chain 9 chr17 Not Cancer Driver No 2358-2371 14 9.46e-03 100.0 10 0.97 1026 SKCM LUAD, UCEC, LGG, SKCM, HNSC, LUSC
MEP1A Q16819 MEP1A Meprin A subunit alpha chr6 Not Cancer Driver No 458-466 9 9.48e-03 0.0 12 7.23 166 SKCM CESC, UCEC, SKCM, BRCA, KIRC
SLITRK2 Q9H156 SLITRK2 SLIT and NTRK-like protein 2 chrX Not Cancer Driver No 681-692 12 9.48e-03 100.0 13 4.68 278 LUAD STAD, LIHC, LUSC, LUAD
MATN4_ENST00000372754 O95460 MATN4 Matrilin-4 chr20 Not Cancer Driver No 89-93 5 9.49e-03 0.0 9 5.59 161 COAD READ, SKCM, BLCA, LUSC, COAD
TMTC2 Q8N394 TMTC2 Protein O-mannosyl-transferase TMTC2 chr12 Not Cancer Driver No 137-143 7 9.49e-03 0.0 10 6.85 146 BLCA SKCM, KIRC, GBM, LUAD, BLCA
CC2D1A Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A chr19 Not Cancer Driver No 584-588 5 9.50e-03 0.0 9 6.08 148 GBM BRCA, READ, GBM, UCEC
KLHL13_ENST00000262820 Q9P2N7 KLHL13 Kelch-like protein 13 chrX Not Cancer Driver No 158-165 8 9.50e-03 0.0 10 6.29 159 SKCM BLCA, BRCA, PRAD, UCEC, SKCM, CESC
PRDM1 O75626 PRDM1 PR domain zinc finger protein 1 chr6 Census, Compendium Yes 359-367 9 9.50e-03 100.0 12 8.16 147 OV SKCM, OV, LGG, BRCA, UCEC, LUSC, COAD
COL8A1_ENST00000273342 P27658 COL8A1 Collagen alpha-1(VIII) chain chr3 Not Cancer Driver No 118-128 11 9.51e-03 100.0 12 7.69 156 SKCM SKCM, COAD, GBM
CDH4 P55283 CDH4 Cadherin-4 chr20 Not Cancer Driver No 409-420 12 9.51e-03 0.0 14 5.26 266 SKCM STAD, COAD, SKCM, READ, PRAD, BRCA
LUC7L Q9NQ29 LUC7L Putative RNA-binding protein Luc7-like 1 chr16 Not Cancer Driver No 292-318 27 9.51e-03 100.0 12 24.0 50 LUAD, UCEC STAD, SKCM, LUAD, OV, LUSC, UCEC, HNSC
RASSF6 Q6ZTQ3 RASSF6 Ras association domain-containing protein 6 chr4 Not Cancer Driver No 131-163 33 9.51e-03 100.0 15 27.27 55 SKCM LUAD, BLCA, SKCM, KIRC, UCEC, STAD
WDR86_ENST00000334493 Q86TI4 WDR86 WD repeat-containing protein 86 chr7 Not Cancer Driver No 117-148 32 9.51e-03 0.0 13 24.53 53 SKCM, LUSC GBM, BRCA, STAD, SKCM, LUSC, HNSC, LUAD
NLRP7_ENST00000590030 Q8WX94 NLRP7 NACHT, LRR and PYD domains-containing protein 7 chr19 Not Cancer Driver No 411-425 15 9.52e-03 0.0 13 4.33 300 COAD, SKCM CESC, COAD, SKCM, BRCA, LUAD, STAD, PRAD
MORC1 Q86VD1 MORC1 MORC family CW-type zinc finger protein 1 chr3 Not Cancer Driver No 224-238 15 9.53e-03 20.0 15 4.95 303 - KIRC, BRCA, HNSC, BLCA, CESC, SKCM, LUSC, STAD
CBR3 O75828 CBR3 Carbonyl reductase [NADPH] 3 chr21 Not Cancer Driver No 4-4 1 9.53e-03 100.0 12 33.33 36 COAD, READ COAD, READ
PTGDR2 Q9Y5Y4 PTGDR2 Prostaglandin D2 receptor 2 chr11 Not Cancer Driver No 199-204 6 9.53e-03 0.0 14 48.28 29 COAD LUSC, LGG, COAD, READ
RGPD1 P0DJD0 RGPD1 RANBP2-like and GRIP domain-containing protein 1 chr2 Not Cancer Driver No 1330-1360 31 9.53e-03 16.13 7 22.58 31 SKCM SKCM, LUSC, KIRC, GBM, BLCA
GLIS3_ENST00000324333 Q8NEA6 GLIS3 Zinc finger protein GLIS3 chr9 Not Cancer Driver No 298-306 9 9.54e-03 100.0 19 11.38 167 COAD STAD, READ, KIRC, SKCM, COAD
RAB3GAP2 Q9H2M9 RAB3GAP2 Rab3 GTPase-activating protein non-catalytic subunit chr1 Not Cancer Driver No 418-428 11 9.54e-03 0.0 11 6.51 169 UCEC READ, UCEC, HNSC, STAD, LGG, LUSC, CESC
CAT P04040 CAT Catalase chr11 Not Cancer Driver No 330-369 40 9.54e-03 0.0 14 20.0 70 - CESC, OV, SKCM, BLCA, LUAD, UCEC, LUSC, READ, KIRC, STAD
SLC6A3 Q01959 SLC6A3 Sodium-dependent dopamine transporter chr5 Not Cancer Driver No 231-237 7 9.55e-03 0.0 11 7.33 150 LUSC LIHC, LUSC, STAD, SKCM, GBM
TLE4_ENST00000376552 Q04727 TLE4 Transducin-like enhancer protein 4 chr9 Not Cancer Driver No 335-343 9 9.55e-03 100.0 9 5.2 173 COAD LGG, SKCM, LUSC, COAD, STAD
KLHL6 Q8WZ60 KLHL6 Kelch-like protein 6 chr3 Compendium Yes 66-98 33 9.55e-03 0.0 22 14.1 156 STAD LUSC, LUAD, DLBC, COAD, CESC, BLCA, STAD, READ, PRAD, UCEC
LZTR1_ENST00000646124 Q8N653 LZTR1 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 97-105 9 9.56e-03 0.0 13 8.02 162 - STAD, UCEC, THCA, KIRC, GBM, OV, SKCM
LZTR1_ENST00000646124 Q8N653 LZTR1 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 240-248 9 9.56e-03 11.11 11 6.79 162 SKCM SKCM, GBM, UCEC, BLCA, STAD, COAD
LZTR1_ENST00000646124 Q8N653 LZTR1 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 279-286 8 9.56e-03 12.5 9 5.56 162 UCEC UCEC, BLCA, BRCA, STAD, GBM, OV, CESC
TTN_ENST00000615779 Q8WZ42 TTN Titin chr2 Not Cancer Driver No 7688-7707 20 9.56e-03 100.0 17 0.21 7986 SKCM BRCA, SKCM, HNSC, LUAD, UCEC, CESC
AASS Q9UDR5 AASS Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 Not Cancer Driver No 258-273 16 9.56e-03 0.0 11 6.79 162 SKCM LUSC, LUAD, SKCM, BRCA, GBM, READ
CCSER1 Q9C0I3 CCSER1 Serine-rich coiled-coil domain-containing protein 1 chr4 Not Cancer Driver No 544-557 14 9.56e-03 100.0 19 10.44 182 GBM BLCA, HNSC, LUSC, GBM, SARC, SKCM, COAD, STAD
OR11L1 Q8NGX0 OR11L1 Olfactory receptor 11L1 chr1 Not Cancer Driver No 158-162 5 9.56e-03 0.0 13 9.22 141 SKCM LUAD, BLCA, SKCM, LUSC, KIRC
DACH1_ENST00000619232 Q9UI36 DACH1 Dachshund homolog 1 chr13 Not Cancer Driver No 307-314 8 9.57e-03 100.0 10 6.37 157 SKCM, LUAD SKCM, STAD, LUAD, LUSC
KCNV1 Q6PIU1 KCNV1 Potassium voltage-gated channel subfamily V member 1 chr8 Not Cancer Driver No 186-190 5 9.57e-03 40.0 9 6.12 147 SKCM SKCM, HNSC, BRCA, GBM
PCDHGA9 Q9Y5G4 PCDHGA9 Protocadherin gamma-A9 chr5 Not Cancer Driver No 213-222 10 9.57e-03 0.0 10 5.78 173 - SKCM, LUAD, OV, STAD, READ, PRAD, BRCA, SARC
CCDC60 Q8IWA6 CCDC60 Coiled-coil domain-containing protein 60 chr12 Not Cancer Driver No 339-349 11 9.59e-03 100.0 11 7.19 153 SKCM LIHC, SKCM, BRCA, UCEC, CESC
C8A P07357 C8A Complement component C8 alpha chain chr1 Not Cancer Driver No 577-581 5 9.62e-03 0.0 14 7.61 184 - UCEC, COAD, STAD, BLCA, READ, LUSC, GBM
CATSPERD Q86XM0 CATSPERD Cation channel sperm-associated auxiliary subunit delta chr19 Not Cancer Driver No 748-754 7 9.62e-03 100.0 9 4.95 182 SKCM COAD, UCEC, GBM, SKCM, BRCA
THSD4 Q6ZMP0 THSD4 Thrombospondin type-1 domain-containing protein 4 chr15 Not Cancer Driver No 471-479 9 9.62e-03 0.0 10 5.78 173 SKCM LGG, LUAD, SKCM, LUSC, HNSC
VWA3A A6NCI4 VWA3A von Willebrand factor A domain-containing protein 3A chr16 Not Cancer Driver No 872-882 11 9.62e-03 0.0 11 5.82 189 - SKCM, LUSC, HNSC, COT, UCEC, LUAD, COAD
LATS1 O95835 LATS1 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 748-769 22 9.62e-03 0.0 11 6.83 161 LUAD, BLCA BRCA, HNSC, OV, LUAD, BLCA, UCEC, LIHC
SH3RF2 Q8TEC5 SH3RF2 E3 ubiquitin-protein ligase SH3RF2 chr5 Not Cancer Driver No 315-323 9 9.62e-03 100.0 11 7.24 152 GBM, SKCM GBM, SKCM, STAD, LUSC, UCEC
HOXA3_ENST00000396352 O43365 HOXA3 Homeobox protein Hox-A3 chr7 Not Cancer Driver No 249-292 44 9.63e-03 95.45 19 22.09 86 SKCM SKCM, PRAD, STAD, PAAD, HNSC, CESC, BRCA, LUSC, LUAD, BLCA
OR2T2_ENST00000642130 Q6IF00 OR2T2 Olfactory receptor 2T2 chr1 Not Cancer Driver No 137-139 3 9.63e-03 0.0 10 6.49 154 - SKCM, BRCA, LGG, UCEC, READ, LUSC, STAD
SETDB1 Q15047 SETDB1 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 693-703 11 9.63e-03 0.0 10 5.41 185 KIRC OV, SKCM, BLCA, HNSC, KIRC
EYA1_ENST00000647540 Q99502 EYA1 Eyes absent homolog 1 chr8 Not Cancer Driver No 294-304 11 9.64e-03 100.0 12 7.1 169 - BLCA, STAD, UCEC, BRCA, LUAD, HNSC, SKCM
ANKRD35 Q8N283 ANKRD35 Ankyrin repeat domain-containing protein 35 chr1 Not Cancer Driver No 153-160 8 9.64e-03 0.0 10 5.65 177 GBM BRCA, UCEC, LUSC, GBM, BLCA, KIRC
BACH2_ENST00000537989 Q9BYV9 BACH2 Transcription regulator protein BACH2 chr6 Not Cancer Driver No 525-533 9 9.64e-03 100.0 11 6.18 178 BRCA BRCA, STAD, OV, HNSC, PAAD, LUSC
RPS6KA6_ENST00000262752 Q9UK32 RPS6KA6 Ribosomal protein S6 kinase alpha-6 chrX Not Cancer Driver No 658-665 8 9.64e-03 0.0 10 5.56 180 SKCM LUAD, BLCA, GBM, CESC, LUSC, SKCM
GPRASP2 Q96D09 GPRASP2 G-protein coupled receptor-associated sorting protein 2 chrX Not Cancer Driver No 382-422 41 9.66e-03 100.0 16 12.03 133 LUAD KIRC, LUAD, BRCA, CESC, SKCM, HNSC, UCEC, COAD, LUSC
PDPR Q8NCN5 PDPR Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial chr16 Compendium Yes 158-202 45 9.66e-03 0.0 17 11.97 142 SKCM PRAD, READ, SKCM, BRCA, UCEC, OV, KIRC, LUSC, COAD, LUAD
SHANK1 Q9Y566 SHANK1 SH3 and multiple ankyrin repeat domains protein 1 chr19 Not Cancer Driver No 30-84 55 9.66e-03 74.55 18 6.14 293 - STAD, LUSC, SKCM, BLCA, CESC, LUAD, THCA, COAD
PCDHA8 Q9Y5H6 PCDHA8 Protocadherin alpha-8 chr5 Not Cancer Driver No 635-646 12 9.67e-03 0.0 15 4.24 354 - UCEC, SKCM, STAD, BRCA, GBM, CESC, PRAD, LUAD
NME8_ENST00000440017 Q8N427 NME8 Thioredoxin domain-containing protein 3 chr7 Not Cancer Driver No 247-252 6 9.68e-03 100.0 10 5.38 186 SKCM HNSC, LUSC, KIRC, SKCM
PROX1 Q92786 PROX1 Prospero homeobox protein 1 chr1 Not Cancer Driver No 170-176 7 9.69e-03 14.29 12 6.59 182 SKCM KIRC, STAD, SKCM, BRCA
UBAP2L Q14157 UBAP2L Ubiquitin-associated protein 2-like chr1 Not Cancer Driver No 521-568 48 9.69e-03 100.0 18 13.95 129 UCEC PRAD, CESC, LIHC, LUAD, READ, BLCA, COAD, BRCA, UCEC
ZNF229 Q9UJW7 ZNF229 Zinc finger protein 229 chr19 Not Cancer Driver No 581-587 7 9.69e-03 0.0 9 4.13 218 STAD UCEC, STAD, BLCA, CESC, BRCA, READ
MAP3K15 Q6ZN16 MAP3K15 Mitogen-activated protein kinase kinase kinase 15 chrX Not Cancer Driver No 790-800 11 9.70e-03 27.27 9 4.37 206 - BLCA, CESC, SKCM, STAD, UCEC, OV, LIHC, BRCA
TAAR8 Q969N4 TAAR8 Trace amine-associated receptor 8 chr6 Not Cancer Driver No 153-180 28 9.70e-03 0.0 13 25.49 51 LUAD LUAD, LUSC, READ, BLCA, LGG, COAD, SKCM
PCDHA1 Q9Y5I3 PCDHA1 Protocadherin alpha-1 chr5 Not Cancer Driver No 613-624 12 9.70e-03 41.67 13 3.83 339 STAD STAD, LUAD, BRCA, UCEC, GBM, COAD
PPFIA2 O75334 PPFIA2 Liprin-alpha-2 chr12 Not Cancer Driver No 1202-1214 13 9.71e-03 100.0 15 4.39 342 SKCM LUAD, BLCA, SKCM, HNSC, CESC
BAX_ENST00000345358 Q07812 BAX Apoptosis regulator BAX chr19 Census Yes 124-139 16 9.71e-03 0.0 11 36.67 30 COAD BRCA, LUAD, SKCM, LIHC, COAD, LAML, UCEC
DNAJC27 Q9NZQ0 DNAJC27 DnaJ homolog subfamily C member 27 chr2 Not Cancer Driver No 89-109 21 9.71e-03 0.0 11 33.33 33 SKCM SKCM, LUSC, STAD, UCEC, CESC
EPHB2 P29323 EPHB2 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 74-80 7 9.71e-03 0.0 9 4.84 186 - PRAD, SKCM, LUAD, CESC, GBM, LGG, BRCA, OV
MYBPC2 Q14324 MYBPC2 Myosin-binding protein C, fast-type chr19 Not Cancer Driver No 161-171 11 9.71e-03 100.0 13 6.4 203 READ, COAD LUAD, READ, UCEC, COAD
NLRP8 Q86W28 NLRP8 NACHT, LRR and PYD domains-containing protein 8 chr19 Not Cancer Driver No 349-361 13 9.71e-03 0.0 13 3.82 340 SKCM UCEC, HNSC, GBM, BLCA, SKCM, LUAD, BRCA, COAD, CESC
RPRD2 Q5VT52 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 chr1 Not Cancer Driver No 960-984 25 9.72e-03 100.0 11 5.98 184 SKCM LUAD, SKCM, UCEC, LUSC
ASXL1_ENST00000613218 Q8IXJ9 ASXL1 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 606-620 15 9.73e-03 100.0 9 4.37 206 - UCEC, BRCA, SARC, LUSC, GBM, STAD, READ, OV
CADPS2 Q86UW7 CADPS2 Calcium-dependent secretion activator 2 chr7 Not Cancer Driver No 620-631 12 9.73e-03 75.0 10 5.13 195 SKCM BRCA, SKCM, LUAD, UCEC, BLCA, OV
ZNF845 Q96IR2 ZNF845 Zinc finger protein 845 chr19 Not Cancer Driver No 151-165 15 9.73e-03 100.0 19 8.76 217 - SKCM, STAD, GBM, LIHC, LUAD, BLCA, KIRC, CESC
COL19A1 Q14993 COL19A1 Collagen alpha-1(XIX) chain chr6 Not Cancer Driver No 161-174 14 9.73e-03 0.0 17 4.9 347 - LUAD, PRAD, LUSC, STAD, SKCM, BLCA, LGG, HNSC, BRCA, UCEC
GRM4 Q14833 GRM4 Metabotropic glutamate receptor 4 chr6 Not Cancer Driver No 42-49 8 9.74e-03 0.0 11 5.76 191 SKCM SKCM, HNSC, READ, UCEC, GBM, STAD
TET3 O43151 TET3 Methylcytosine dioxygenase TET3 chr2 Not Cancer Driver No 499-508 10 9.75e-03 100.0 10 4.81 208 SKCM BLCA, THCA, SKCM, BRCA, LUSC, GBM, LUAD
SRRM4 A7MD48 SRRM4 Serine/arginine repetitive matrix protein 4 chr12 Not Cancer Driver No 558-565 8 9.75e-03 100.0 13 7.1 183 STAD, COAD, UCEC STAD, CESC, COAD, UCEC
MAGEL2 Q9UJ55 MAGEL2 MAGE-like protein 2 chr15 Not Cancer Driver No 1015-1026 12 9.75e-03 33.33 9 5.03 179 - UCEC, SKCM, LUSC, BRCA, READ, LUAD, STAD
PELP1_ENST00000574876 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 chr17 Not Cancer Driver No 473-523 51 9.75e-03 88.46 21 15.67 134 SKCM OV, COAD, LIHC, LUSC, UCEC, STAD, SKCM
SOS1_ENST00000402219 Q07889 SOS1 Son of sevenless homolog 1 chr2 Compendium Yes 548-555 8 9.76e-03 0.0 9 4.57 197 UCEC, BLCA UCEC, LUSC, LAML, BLCA, LIHC
NAA60_ENST00000572584 Q9H7X0 NAA60 N-alpha-acetyltransferase 60 chr16 Not Cancer Driver No 153-183 31 9.76e-03 0.0 13 39.39 33 - LUSC, BRCA, PAAD, KIRC, CESC, SKCM, UCEC, LUAD, HNSC
ODF3L2 Q3SX64 ODF3L2 Outer dense fiber protein 3-like protein 2 chr19 Not Cancer Driver No 227-265 39 9.76e-03 100.0 16 42.11 38 - STAD, READ, BLCA, LUSC, GBM, SKCM, LUAD, HNSC, CESC
FOLH1 Q04609 FOLH1 Glutamate carboxypeptidase 2 chr11 Not Cancer Driver No 171-177 7 9.77e-03 0.0 9 4.48 201 LUAD LUSC, SKCM, THCA, STAD, BRCA, LUAD
NPAS3 Q8IXF0 NPAS3 Neuronal PAS domain-containing protein 3 chr14 Not Cancer Driver No 469-475 7 9.77e-03 100.0 9 4.62 195 GBM GBM
KIF4A O95239 KIF4A Chromosome-associated kinesin KIF4A chrX Not Cancer Driver No 647-660 14 9.78e-03 0.0 11 5.85 188 SKCM SKCM, COAD, SARC, BRCA, HNSC, CESC
ADAM19_ENST00000517905 Q9H013 ADAM19 Disintegrin and metalloproteinase domain-containing protein 19 chr5 Not Cancer Driver No 835-848 14 9.79e-03 100.0 14 8.0 175 - CESC, COAD, UCEC, LUSC, KIRC, SKCM, LUAD, STAD
GRID2 O43424 GRID2 Glutamate receptor ionotropic, delta-2 chr4 Not Cancer Driver No 530-539 10 9.79e-03 0.0 15 4.25 353 - UCEC, PRAD, DLBC, SARC, STAD, SKCM, LUAD, KIRC, BLCA, HNSC, LUSC
MEFV O15553 MEFV Pyrin chr16 Not Cancer Driver No 348-354 7 9.80e-03 100.0 10 4.74 211 - OV, SARC, STAD, LUAD, GBM, PAAD, BRCA
CASS4 Q9NQ75 CASS4 Cas scaffolding protein family member 4 chr20 Not Cancer Driver No 269-273 5 9.80e-03 100.0 9 4.37 206 LUAD LUSC, LUAD, SKCM, STAD
TSHZ3 Q63HK5 TSHZ3 Teashirt homolog 3 chr19 Not Cancer Driver No 670-680 11 9.80e-03 100.0 13 3.67 354 LUAD, SKCM LUAD, HNSC, READ, SKCM
GRM6_ENST00000517717 O15303 GRM6 Metabotropic glutamate receptor 6 chr5 Not Cancer Driver No 854-860 7 9.81e-03 100.0 12 5.74 209 SKCM COAD, SKCM, STAD, LUSC
DLGAP4_ENST00000339266 Q9Y2H0 DLGAP4 Disks large-associated protein 4 chr20 Not Cancer Driver No 175-188 14 9.81e-03 100.0 11 6.43 171 UCEC LGG, GBM, SKCM, UCEC, STAD, LUSC
CD79B_ENST00000006750 P40259 CD79B B-cell antigen receptor complex-associated protein beta chain chr17 Census, Compendium Yes 191-196 6 9.83e-03 100.0 6 24.0 25 DLBC LUAD, DLBC
RAB22A Q9UL26 RAB22A Ras-related protein Rab-22A chr20 Not Cancer Driver No 31-35 5 9.83e-03 0.0 6 26.09 23 - CESC, BRCA, KIRC, STAD, SKCM, LUSC
RANBP2 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 chr2 Census, Compendium Yes 2058-2092 35 9.83e-03 100.0 15 3.49 430 - HNSC, UCEC, STAD, LIHC, PRAD, SKCM, SARC, KIRC
CACNA1H O95180 CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H chr16 Not Cancer Driver No 2149-2198 50 9.83e-03 100.0 19 5.69 334 SKCM LUAD, GBM, SKCM, KIRC, BLCA, LUSC, STAD, HNSC
SORCS1 Q8WY21 SORCS1 VPS10 domain-containing receptor SorCS1 chr10 Not Cancer Driver No 97-107 11 9.85e-03 100.0 13 3.5 371 OV LUSC, STAD, COAD, HNSC, LUAD, OV
DCAF5 Q96JK2 DCAF5 DDB1- and CUL4-associated factor 5 chr14 Not Cancer Driver No 453-462 10 9.85e-03 100.0 6 5.04 119 CESC, BLCA, SKCM CESC, STAD, BLCA, SKCM
HTR3E_ENST00000415389 A5X5Y0 HTR3E 5-hydroxytryptamine receptor 3E chr3 Not Cancer Driver No 335-381 47 9.85e-03 76.6 20 22.73 88 - BRCA, COAD, STAD, GBM, UCEC, SKCM, CESC, LUSC, LUAD
CDH18_ENST00000274170 Q13634 CDH18 Cadherin-18 chr5 Not Cancer Driver No 104-111 8 9.85e-03 0.0 14 3.64 385 LUSC BRCA, STAD, LUAD, SKCM, GBM, LUSC, LIHC
NXN Q6DKJ4 NXN Nucleoredoxin chr17 Not Cancer Driver No 136-183 48 9.86e-03 0.0 18 31.03 58 SKCM SKCM, KIRC, CESC, UCEC, LUSC, STAD
PTPRH Q9HD43 PTPRH Receptor-type tyrosine-protein phosphatase H chr19 Not Cancer Driver No 1070-1078 9 9.86e-03 0.0 9 3.83 235 - LUSC, BLCA, LAML, SKCM, STAD, LUAD, GBM, KIRC
DCDC1_ENST00000597505 M0R2J8 DCDC1 Doublecortin domain-containing protein 1 chr11 Not Cancer Driver No 303-316 14 9.87e-03 28.57 13 3.27 397 SKCM, LUAD SKCM, LUAD, BLCA, LIHC, UCEC, LUSC
TNKS1BP1 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein chr11 Not Cancer Driver No 62-75 14 9.87e-03 100.0 9 3.96 227 SKCM SKCM, LUAD, LUSC, STAD, BRCA, BLCA
SALL4 Q9UJQ4 SALL4 Sal-like protein 4 chr20 Census, Compendium Yes 363-370 8 9.87e-03 100.0 10 4.08 245 UCEC HNSC, SKCM, STAD, COAD, UCEC
SALL4 Q9UJQ4 SALL4 Sal-like protein 4 chr20 Census, Compendium Yes 738-746 9 9.87e-03 100.0 11 4.49 245 SKCM COAD, UCEC, KIRC, SKCM, LUSC, LIHC
ADCY5 O95622 ADCY5 Adenylate cyclase type 5 chr3 Not Cancer Driver No 1055-1061 7 9.88e-03 100.0 10 4.26 235 READ READ, STAD, GBM, SARC, CESC, UCEC, OV
RBM22 Q9NW64 RBM22 Pre-mRNA-splicing factor RBM22 chr5 Not Cancer Driver No 369-395 27 9.88e-03 100.0 12 23.53 51 SKCM KIRC, UCEC, LUSC, SKCM, STAD, LUAD
ZC3H15 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 chr2 Not Cancer Driver No 298-331 34 9.88e-03 100.0 14 24.14 58 BRCA UCEC, KIRC, BLCA, BRCA, LUSC, CESC, SKCM, PAAD, LUAD
AC008770.2_ENST00000591944 K7EJH5 AC008770.2 KRAB domain-containing protein chr19 Not Cancer Driver No 87-95 9 9.88e-03 100.0 10 71.43 14 SKCM, COAD SKCM, THCA, BRCA, COAD, OV
DEFB123 Q8N688 DEFB123 Beta-defensin 123 chr20 Not Cancer Driver No 41-47 7 9.88e-03 0.0 7 63.64 11 LUSC, BLCA LUSC, BLCA, LUAD, SKCM
TET2 Q6N021 TET2 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 10-39 30 9.88e-03 100.0 11 5.7 193 SKCM LGG, LUSC, SKCM, READ, STAD
AOX1 Q06278 AOX1 Aldehyde oxidase chr2 Not Cancer Driver No 503-512 10 9.89e-03 0.0 10 4.2 238 GBM SKCM, LIHC, BRCA, LGG, GBM
CFAP47 Q6ZTR5 CFAP47 Cilia- and flagella-associated protein 47 chrX Not Cancer Driver No 108-137 30 9.89e-03 100.0 17 3.85 441 SKCM OV, CESC, SKCM, SARC
SLC39A12 Q504Y0 SLC39A12 Zinc transporter ZIP12 chr10 Not Cancer Driver No 365-369 5 9.89e-03 0.0 10 4.65 215 HNSC HNSC, LUAD, OV, SKCM, BLCA, LUSC
SLC6A2_ENST00000568943 P23975 SLC6A2 Sodium-dependent noradrenaline transporter chr16 Not Cancer Driver No 564-605 42 9.89e-03 0.0 19 14.96 127 - UCEC, COAD, BLCA, READ, SKCM, LGG, CESC, LUSC, OV, LUAD
ZBTB16_ENST00000392996 Q05516 ZBTB16 Zinc finger and BTB domain-containing protein 16 chr11 Census, Compendium Yes 496-538 43 9.89e-03 65.12 21 16.03 131 - STAD, SKCM, PRAD, HNSC, READ, CESC, LUAD, LUSC, LGG, UCEC, KIRC
NPHS1 O60500 NPHS1 Nephrin chr19 Not Cancer Driver No 798-802 5 9.89e-03 0.0 9 3.85 234 - UCEC, LGG, LUAD, SARC, SKCM, LUSC, HNSC, OV
OBSL1 O75147 OBSL1 Obscurin-like protein 1 chr2 Not Cancer Driver No 366-379 14 9.89e-03 0.0 9 3.77 239 UCEC BLCA, READ, STAD, UCEC, HNSC
DENND2A_ENST00000496613 Q9ULE3 DENND2A DENN domain-containing protein 2A chr7 Not Cancer Driver No 305-315 11 9.91e-03 100.0 11 5.73 192 LUAD BLCA, HNSC, LUSC, KIRC, GBM, OV, LUAD, CESC
WSCD2 Q2TBF2 WSCD2 WSC domain-containing protein 2 chr12 Not Cancer Driver No 113-121 9 9.91e-03 100.0 11 6.21 177 BRCA SKCM, LUAD, HNSC, STAD, BRCA, LUSC
CDH20_ENST00000538374 Q9HBT6 CDH20 Cadherin-20 chr18 Not Cancer Driver No 23-32 10 9.92e-03 100.0 12 6.15 195 SKCM BRCA, UCEC, SKCM, PAAD, LUAD, STAD, LUSC
NPAS3 Q8IXF0 NPAS3 Neuronal PAS domain-containing protein 3 chr14 Not Cancer Driver No 56-69 14 9.92e-03 0.0 11 5.64 195 SKCM LUAD, SKCM, HNSC, OV, LUSC, LIHC, COAD
TNIK Q9UKE5 TNIK TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 943-950 8 9.92e-03 100.0 10 3.92 255 UCEC UCEC, OV, HNSC, PRAD, SKCM
PCDH19 Q8TAB3 PCDH19 Protocadherin-19 chrX Not Cancer Driver No 281-286 6 9.93e-03 0.0 9 3.36 268 STAD, BRCA COAD, STAD, BLCA, BRCA, COT
NLRP9 Q7RTR0 NLRP9 NACHT, LRR and PYD domains-containing protein 9 chr19 Not Cancer Driver No 411-417 7 9.94e-03 0.0 10 4.03 248 SKCM UCEC, KIRC, LUSC, SKCM
CPXM2 Q8N436 CPXM2 Inactive carboxypeptidase-like protein X2 chr10 Not Cancer Driver No 528-538 11 9.94e-03 0.0 12 6.03 199 SKCM UCEC, BLCA, STAD, READ, LUAD, SKCM
ELOA2 Q8IYF1 ELOA2 Elongin-A2 chr18 Not Cancer Driver No 105-109 5 9.94e-03 100.0 9 3.78 238 SKCM CESC, READ, GBM, BRCA, SKCM
SHROOM3 Q8TF72 SHROOM3 Protein Shroom3 chr4 Not Cancer Driver No 709-722 14 9.94e-03 100.0 10 3.95 253 GBM BRCA, GBM, UCEC, PRAD, SKCM, OV
OCA2 Q04671 OCA2 P protein chr15 Not Cancer Driver No 548-560 13 9.96e-03 0.0 15 7.5 200 LUSC LUAD, LUSC, DLBC, GBM, STAD, COAD
CLSTN2 Q9H4D0 CLSTN2 Calsyntenin-2 chr3 Not Cancer Driver No 753-759 7 9.96e-03 0.0 9 3.86 233 LUAD READ, LIHC, LUAD, SKCM, SARC, GBM, HNSC
DGKI O75912 DGKI Diacylglycerol kinase iota chr7 Not Cancer Driver No 719-725 7 9.96e-03 57.14 9 3.69 244 SKCM LUSC, SKCM, HNSC, UCEC
NHS Q6T4R5 NHS Nance-Horan syndrome protein chrX Not Cancer Driver No 560-567 8 9.96e-03 100.0 11 3.96 278 OV OV, LAML, UCEC, LGG
GRM6_ENST00000517717 O15303 GRM6 Metabotropic glutamate receptor 6 chr5 Not Cancer Driver No 430-441 12 9.96e-03 0.0 14 6.7 209 SKCM GBM, LUAD, STAD, COAD, SKCM, BRCA, UCEC, CESC
PCDHB4 Q9Y5E5 PCDHB4 Protocadherin beta-4 chr5 Not Cancer Driver No 39-44 6 9.97e-03 0.0 9 3.52 256 - SKCM, HNSC, BRCA, BLCA, UCEC, LUAD
PTCHD4 Q6ZW05 PTCHD4 Patched domain-containing protein 4 chr6 Not Cancer Driver No 687-696 10 9.97e-03 0.0 12 6.0 200 - SKCM, LGG, SARC, LUSC, KIRC, UCEC, LUAD
DNAH1 Q9P2D7 DNAH1 Dynein axonemal heavy chain 1 chr3 Not Cancer Driver No 2655-2687 33 9.97e-03 100.0 18 3.58 503 - LUAD, SKCM, OV, BLCA, COAD, BRCA, LIHC, STAD, HNSC, LUSC
ATP8B4_ENST00000559829 Q8TF62 ATP8B4 Probable phospholipid-transporting ATPase IM chr15 Not Cancer Driver No 359-367 9 9.97e-03 0.0 9 3.69 244 - LUAD, STAD, LUSC, BLCA, SKCM, READ
CROCC Q5TZA2 CROCC Rootletin chr1 Not Cancer Driver No 584-590 7 9.97e-03 28.57 9 3.44 262 - LUAD, COAD, BRCA, READ, REO, SKCM
CSPG4 Q6UVK1 CSPG4 Chondroitin sulfate proteoglycan 4 chr15 Not Cancer Driver No 435-450 16 9.99e-03 0.0 10 3.85 260 - BRCA, KIRC, SKCM, LAML, LUAD, CESC
ITGAX_ENST00000268296 P20702 ITGAX Integrin alpha-X chr16 Not Cancer Driver No 682-687 6 9.99e-03 0.0 9 3.63 248 LUSC SKCM, LAML, GBM, LUSC
LINGO2_ENST00000308675 Q7L985 LINGO2 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 chr9 Not Cancer Driver No 108-116 9 9.99e-03 0.0 11 5.14 214 - SKCM, BRCA, OV, HNSC, COAD, LUAD, STAD, GBM
MYO1F O00160 MYO1F Unconventional myosin-If chr19 Not Cancer Driver No 22-36 15 9.99e-03 0.0 11 5.26 209 SKCM BRCA, READ, SKCM, LGG, STAD, BLCA
NUP98_ENST00000359171 P52948 NUP98 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 137-162 26 9.99e-03 96.15 12 5.24 229 SKCM LUAD, SKCM, KIRC, STAD, BRCA, PRAD