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Total number of protein in "GO:0051240" GO term:  1236

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0051240 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0051240 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0051240 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0051240 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0051240 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0051240 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACADL ACADL P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial chr2 GO:0051240 Not Cancer Driver No 63 0.147 51 3 0.059 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0051240 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0051240 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACHE_ENST00000241069 ACHE P22303 Acetylcholinesterase chr7 GO:0051240 Not Cancer Driver No 81 0.132 64 8 0.125 0
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 GO:0051240 Not Cancer Driver No 157 0.117 1294 155 0.12 0
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0051240 Not Cancer Driver No 85 0.122 27 1 0.037 0
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0051240 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0051240 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0051240 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0051240 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0051240 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0051240 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0051240 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0051240 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0051240 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0051240 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADCYAP1_ENST00000450565 ADCYAP1 P18509 Pituitary adenylate cyclase-activating polypeptide chr18 GO:0051240 Not Cancer Driver No 43 0.244 75 11 0.147 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0051240 Compendium Yes 213 0.134 485 47 0.097 0
ADGRB3_ENST00000546190 ADGRB3 O60242 Adhesion G protein-coupled receptor B3 chr6 GO:0051240 Not Cancer Driver No 558 0.367 336 149 0.443 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0051240 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0051240 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0051240 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADIPOR2 ADIPOR2 Q86V24 Adiponectin receptor protein 2 chr12 GO:0051240 Not Cancer Driver No 44 0.114 82 7 0.085 0
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0051240 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADM2_ENST00000395737 ADM2 Q7Z4H4 Protein ADM2 chr22 GO:0051240 Not Cancer Driver No 14 0.095 113 11 0.097 0
ADM5 ADM5 C9JUS6 Putative adrenomedullin-5-like protein chr19 GO:0051240 Not Cancer Driver No 6 0.039 35 4 0.114 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0051240 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0051240 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0051240 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0051240 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA1B ADRA1B P35368 Alpha-1B adrenergic receptor chr5 GO:0051240 Not Cancer Driver No 53 0.102 132 1 0.008 0
ADRA1D ADRA1D P25100 Alpha-1D adrenergic receptor chr20 GO:0051240 Not Cancer Driver No 62 0.108 189 19 0.101 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0051240 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRB1 ADRB1 P08588 Beta-1 adrenergic receptor chr10 GO:0051240 Not Cancer Driver No 35 0.073 116 1 0.009 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0051240 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADRB3 ADRB3 P13945 Beta-3 adrenergic receptor chr8 GO:0051240 Not Cancer Driver No 40 0.098 44 6 0.136 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0051240 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0051240 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0051240 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGRN AGRN O00468 Agrin chr1 GO:0051240 Not Cancer Driver No 188 0.091 490 40 0.082 5
AGT AGT P01019 Angiotensinogen chr1 GO:0051240 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0051240 Not Cancer Driver No 98 0.27 0 0 0.0 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0051240 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0051240 Not Cancer Driver No 73 0.213 78 22 0.282 0
AIRE AIRE O43918 Autoimmune regulator chr21 GO:0051240 Not Cancer Driver No 71 0.13 338 48 0.142 19
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0051240 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0051240 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKIRIN2 AKIRIN2 Q53H80 Akirin-2 chr6 GO:0051240 Not Cancer Driver No 21 0.103 119 11 0.092 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0051240 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALMS1 ALMS1 Q8TCU4 Alstrom syndrome protein 1 chr2 GO:0051240 Not Cancer Driver No 537 0.129 3518 441 0.125 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 GO:0051240 Not Cancer Driver No 101 0.144 16 3 0.188 18
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0051240 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0051240 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0051240 Not Cancer Driver No 80 0.153 184 39 0.212 113
ALX1 ALX1 Q15699 ALX homeobox protein 1 chr12 GO:0051240 Not Cancer Driver No 75 0.23 190 48 0.253 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0051240 Not Cancer Driver No 173 0.133 788 103 0.131 0
AMELX_ENST00000380714 AMELX Q99217 Amelogenin, X isoform chrX GO:0051240 Not Cancer Driver No 40 0.209 127 28 0.22 3
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0051240 Not Cancer Driver No 46 0.093 85 7 0.082 0
AMIGO2_ENST00000429635 AMIGO2 Q86SJ2 Amphoterin-induced protein 2 chr12 GO:0051240 Not Cancer Driver No 81 0.155 44 6 0.136 0
AMIGO3 AMIGO3 Q86WK7 Amphoterin-induced protein 3 chr3 GO:0051240 Not Cancer Driver No 69 0.137 60 7 0.117 0
AMOT AMOT Q4VCS5 Angiomotin chrX GO:0051240 Not Cancer Driver No 161 0.149 909 128 0.141 0
AMTN AMTN Q6UX39 Amelotin chr4 GO:0051240 Not Cancer Driver No 39 0.187 126 28 0.222 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0051240 Not Cancer Driver No 104 0.127 146 26 0.178 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0051240 Not Cancer Driver No 145 0.138 239 33 0.138 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0051240 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0051240 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0051240 Not Cancer Driver No 49 0.145 20 4 0.2 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0051240 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0051240 Not Cancer Driver No 138 0.12 404 59 0.146 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0051240 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0051240 Not Cancer Driver No 1 0.019 0 0 0.0 0
APLN APLN Q9ULZ1 Apelin chrX GO:0051240 Not Cancer Driver No 8 0.104 51 6 0.118 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0051240 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0051240 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0051240 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0051240 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0051240 Not Cancer Driver No 67 0.194 0 0 0.0 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0051240 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0051240 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0051240 Not Cancer Driver No 70 0.105 149 14 0.094 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0051240 Not Cancer Driver No 39 0.145 4 1 0.25 0
AR AR P10275 Androgen receptor chrX GO:0051240 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 GO:0051240 Not Cancer Driver No 254 0.142 358 63 0.176 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0051240 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0051240 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0051240 Census Yes 77 0.098 511 56 0.11 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0051240 Not Cancer Driver No 46 0.112 122 22 0.18 0
ARX ARX Q96QS3 Homeobox protein ARX chrX GO:0051240 Not Cancer Driver No 33 0.059 423 18 0.043 9
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0051240 Not Cancer Driver No 101 0.197 49 1 0.02 0
ASPA ASPA P45381 Aspartoacylase chr17 GO:0051240 Not Cancer Driver No 58 0.185 3 0 0.0 42
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0051240 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0051240 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0051240 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0051240 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0051240 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0051240 Census Yes 115 0.112 115 16 0.139 6
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0051240 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0051240 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0051240 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0051240 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0051240 Not Cancer Driver No 56 0.16 0 0 0.0 2
ATP8A2 ATP8A2 Q9NTI2 Phospholipid-transporting ATPase IB chr13 GO:0051240 Not Cancer Driver No 236 0.199 78 14 0.179 1
ATRAID_ENST00000606999 ATRAID Q6UW56 All-trans retinoic acid-induced differentiation factor chr2 GO:0051240 Not Cancer Driver No 15 0.066 9 2 0.222 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0051240 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0051240 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0051240 Not Cancer Driver No 83 0.196 51 5 0.098 0
AVPR2_ENST00000337474 AVPR2 P30518 Vasopressin V2 receptor chrX GO:0051240 Not Cancer Driver No 58 0.156 56 7 0.125 84
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0051240 Census, Compendium Yes 114 0.135 547 77 0.141 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0051240 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0051240 Not Cancer Driver No 42 0.167 53 13 0.245 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0051240 Census, Compendium Yes 34 0.286 5 1 0.2 2
B4GALT5 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 GO:0051240 Not Cancer Driver No 53 0.137 20 1 0.05 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0051240 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0051240 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAMBI BAMBI Q13145 BMP and activin membrane-bound inhibitor homolog chr10 GO:0051240 Not Cancer Driver No 42 0.162 31 7 0.226 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 GO:0051240 Not Cancer Driver No 39 0.172 227 39 0.172 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0051240 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0051240 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0051240 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0051240 Census Yes 44 0.097 259 23 0.089 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0051240 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCL9L BCL9L Q86UU0 B-cell CLL/lymphoma 9-like protein chr11 GO:0051240 Census, Compendium Yes 200 0.133 1495 200 0.134 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0051240 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0051240 Not Cancer Driver No 45 0.1 190 19 0.1 0
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0051240 Not Cancer Driver No 88 0.161 267 38 0.142 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0051240 Not Cancer Driver No 65 0.11 456 42 0.092 5
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 GO:0051240 Not Cancer Driver No 119 0.121 154 25 0.162 3
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0051240 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0051240 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0051240 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0051240 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0051240 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPER BMPER Q8N8U9 BMP-binding endothelial regulator protein chr7 GO:0051240 Not Cancer Driver No 196 0.286 0 0 0.0 1
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0051240 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0051240 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0051240 Compendium Yes 141 0.136 601 70 0.116 19
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0051240 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BSCL2_ENST00000421906 BSCL2 Q96G97 Seipin chr11 GO:0051240 Not Cancer Driver No 55 0.138 125 15 0.12 5
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0051240 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0051240 Not Cancer Driver No 92 0.176 24 2 0.083 0
BTN3A1 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0051240 Not Cancer Driver No 77 0.15 72 18 0.25 0
BTN3A2 BTN3A2 P78410 Butyrophilin subfamily 3 member A2 chr6 GO:0051240 Not Cancer Driver No 63 0.189 45 6 0.133 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0051240 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0051240 Not Cancer Driver No 61 0.217 96 17 0.177 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0051240 Not Cancer Driver No 42 0.171 73 14 0.192 0
C1QTNF4 C1QTNF4 Q9BXJ3 Complement C1q tumor necrosis factor-related protein 4 chr11 GO:0051240 Not Cancer Driver No 25 0.076 91 4 0.044 0
C3 C3 P01024 Complement C3 chr19 GO:0051240 Not Cancer Driver No 337 0.203 287 50 0.174 12
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0051240 Not Cancer Driver No 88 0.183 72 16 0.222 0
C5 C5 P01031 Complement C5 chr9 GO:0051240 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0051240 Not Cancer Driver No 71 0.203 0 0 0.0 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 GO:0051240 Not Cancer Driver No 86 0.129 273 28 0.103 6
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0051240 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0051240 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAPRIN1_ENST00000532820 CAPRIN1 Q14444 Caprin-1 chr11 GO:0051240 Not Cancer Driver No 84 0.118 603 72 0.119 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0051240 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0051240 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0051240 Not Cancer Driver No 72 0.134 225 35 0.156 11
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0051240 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0051240 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0051240 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0051240 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0051240 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0051240 Census, Compendium Yes 39 0.214 94 17 0.181 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0051240 Census Yes 160 0.163 562 104 0.185 0
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0051240 Not Cancer Driver No 46 0.238 14 2 0.143 0
CBLN2 CBLN2 Q8IUK8 Cerebellin-2 chr18 GO:0051240 Not Cancer Driver No 78 0.348 35 8 0.229 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0051240 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0051240 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0051240 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0051240 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0051240 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0051240 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0051240 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0051240 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0051240 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 GO:0051240 Not Cancer Driver No 42 0.112 60 5 0.083 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0051240 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0051240 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0051240 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0051240 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0051240 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0051240 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0051240 Census Yes 29 0.1 54 9 0.167 0
CD276 CD276 Q5ZPR3 CD276 antigen chr15 GO:0051240 Not Cancer Driver No 62 0.116 139 10 0.072 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0051240 Census Yes 42 0.191 18 10 0.556 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0051240 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0051240 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0051240 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0051240 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0051240 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0051240 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD40LG CD40LG P29965 CD40 ligand chrX GO:0051240 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0051240 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0051240 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD58 CD58 P19256 Lymphocyte function-associated antigen 3 chr1 GO:0051240 Compendium Yes 29 0.116 12 2 0.167 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0051240 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0051240 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0051240 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0051240 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0051240 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0051240 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0051240 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDH4 CDH4 P55283 Cadherin-4 chr20 GO:0051240 Not Cancer Driver No 266 0.29 441 152 0.345 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0051240 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0051240 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0051240 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0051240 Not Cancer Driver No 165 0.172 685 120 0.175 18
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0051240 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0051240 Not Cancer Driver No 13 0.087 141 12 0.085 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 GO:0051240 Not Cancer Driver No 21 0.127 4 0 0.0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0051240 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0051240 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0051240 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHGA CHGA P10645 Chromogranin-A chr14 GO:0051240 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0051240 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 GO:0051240 Not Cancer Driver No 116 0.244 42 10 0.238 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 GO:0051240 Not Cancer Driver No 182 0.308 136 42 0.309 0
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 GO:0051240 Not Cancer Driver No 98 0.197 30 6 0.2 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0051240 Not Cancer Driver No 74 0.099 116 9 0.078 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0051240 Not Cancer Driver No 24 0.126 6 1 0.167 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0051240 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0051240 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0051240 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLECL1_ENST00000327839 CLECL1 Q8IZS7 C-type lectin-like domain family 1 chr12 GO:0051240 Not Cancer Driver No 18 0.108 0 0 0.0 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0051240 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLSTN1 CLSTN1 O94985 Calsyntenin-1 chr1 GO:0051240 Not Cancer Driver No 110 0.112 271 22 0.081 0
CLSTN2 CLSTN2 Q9H4D0 Calsyntenin-2 chr3 GO:0051240 Not Cancer Driver No 232 0.243 177 41 0.232 0
CLSTN3 CLSTN3 Q9BQT9 Calsyntenin-3 chr12 GO:0051240 Not Cancer Driver No 140 0.146 211 27 0.128 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0051240 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0051240 Not Cancer Driver No 107 0.287 24 13 0.542 0
CNOT3 CNOT3 O75175 CCR4-NOT transcription complex subunit 3 chr19 GO:0051240 Census, Compendium Yes 120 0.159 538 78 0.145 4
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0051240 Not Cancer Driver No 129 0.273 9 1 0.111 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0051240 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0051240 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPT2 CPT2 P23786 Carnitine O-palmitoyltransferase 2, mitochondrial chr1 GO:0051240 Not Cancer Driver No 66 0.1 70 5 0.071 21
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0051240 Compendium Yes 383 0.188 151 42 0.278 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0051240 Not Cancer Driver No 27 0.196 23 6 0.261 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0051240 Not Cancer Driver No 155 0.121 72 0 0.0 5
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0051240 Census Yes 25 0.076 277 23 0.083 0
CRH CRH P06850 Corticoliberin chr8 GO:0051240 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX GO:0051240 Census Yes 54 0.146 62 3 0.048 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0051240 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0051240 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0051240 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0051240 Not Cancer Driver No 11 0.076 34 3 0.088 0
CST7 CST7 O76096 Cystatin-F chr20 GO:0051240 Not Cancer Driver No 12 0.083 15 2 0.133 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0051240 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0051240 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 GO:0051240 Not Cancer Driver No 78 0.142 465 56 0.12 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0051240 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0051240 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0051240 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0051240 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0051240 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0051240 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0051240 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0051240 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0051240 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0051240 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0051240 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0051240 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP8B1 CYP8B1 Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase chr3 GO:0051240 Not Cancer Driver No 91 0.182 5 1 0.2 0
CYSLTR1 CYSLTR1 Q9Y271 Cysteinyl leukotriene receptor 1 chrX GO:0051240 Not Cancer Driver No 58 0.172 8 1 0.125 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0051240 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0051240 Not Cancer Driver No 102 0.114 485 61 0.126 4
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0051240 Not Cancer Driver No 125 0.203 71 17 0.239 3
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0051240 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0051240 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0051240 Compendium Yes 150 0.319 6 3 0.5 0
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0051240 Not Cancer Driver No 113 0.218 19 4 0.211 2
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0051240 Census Yes 29 0.172 160 27 0.169 0
DDT_ENST00000350608 DDT P30046 D-dopachrome decarboxylase chr22 GO:0051240 Not Cancer Driver No 4 0.034 0 0 0.0 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0051240 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0051240 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0051240 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0051240 Not Cancer Driver No 118 0.128 61 10 0.164 2
DECR1 DECR1 Q16698 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial chr8 GO:0051240 Not Cancer Driver No 38 0.113 11 0 0.0 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0051240 Not Cancer Driver No 9 0.127 3 0 0.0 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0051240 Not Cancer Driver No 69 0.089 299 19 0.064 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0051240 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0051240 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX37 DHX37 Q8IY37 Probable ATP-dependent RNA helicase DHX37 chr12 GO:0051240 Not Cancer Driver No 165 0.143 433 66 0.152 5
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0051240 Not Cancer Driver No 62 0.091 84 8 0.095 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0051240 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0051240 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:0051240 Not Cancer Driver No 73 0.267 44 4 0.091 0
DIO3 DIO3 P55073 Thyroxine 5-deiodinase chr14 GO:0051240 Not Cancer Driver No 88 0.289 71 18 0.254 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0051240 Not Cancer Driver No 132 0.155 514 82 0.16 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0051240 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0051240 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0051240 Not Cancer Driver No 115 0.159 145 24 0.166 1
DMRT1 DMRT1 Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 chr9 GO:0051240 Not Cancer Driver No 60 0.161 282 47 0.167 0
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0051240 Not Cancer Driver No 25 0.046 325 19 0.058 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0051240 Not Cancer Driver No 53 0.131 348 46 0.132 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0051240 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0051240 Not Cancer Driver No 88 0.22 45 17 0.378 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0051240 Not Cancer Driver No 652 0.324 603 201 0.333 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0051240 Not Cancer Driver No 81 0.168 135 24 0.178 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 GO:0051240 Not Cancer Driver No 505 0.109 495 62 0.125 21
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0051240 Not Cancer Driver No 49 0.112 272 23 0.085 0
EBF2 EBF2 Q9HAK2 Transcription factor COE2 chr8 GO:0051240 Not Cancer Driver No 158 0.275 261 71 0.272 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0051240 Not Cancer Driver No 32 0.14 10 1 0.1 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0051240 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0051240 Not Cancer Driver No 21 0.118 87 13 0.149 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0051240 Not Cancer Driver No 69 0.29 140 44 0.314 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0051240 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0051240 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0051240 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0051240 Not Cancer Driver No 42 0.126 97 15 0.155 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0051240 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0051240 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0051240 Compendium Yes 90 0.189 352 59 0.168 11
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0051240 Not Cancer Driver No 60 0.155 252 46 0.183 0
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 GO:0051240 Not Cancer Driver No 182 0.14 701 97 0.138 1
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0051240 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0051240 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0051240 Not Cancer Driver No 104 0.115 382 43 0.113 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0051240 Not Cancer Driver No 39 0.146 18 3 0.167 89
ELOVL3 ELOVL3 Q9HB03 Elongation of very long chain fatty acids protein 3 chr10 GO:0051240 Not Cancer Driver No 42 0.156 1 1 1.0 0
ELOVL6 ELOVL6 Q9H5J4 Elongation of very long chain fatty acids protein 6 chr4 GO:0051240 Not Cancer Driver No 40 0.151 0 0 0.0 0
ENAM ENAM Q9NRM1 Enamelin chr4 GO:0051240 Not Cancer Driver No 251 0.22 1095 244 0.223 2
ENG ENG P17813 Endoglin chr9 GO:0051240 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0051240 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 GO:0051240 Not Cancer Driver No 79 0.174 20 4 0.2 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0051240 Not Cancer Driver No 102 0.223 65 19 0.292 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0051240 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0051240 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0051240 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0051240 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0051240 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0051240 Not Cancer Driver No 144 0.201 55 6 0.109 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0051240 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0051240 Census, Compendium Yes 428 0.327 323 116 0.359 2
EREG EREG O14944 Proepiregulin chr4 GO:0051240 Not Cancer Driver No 26 0.154 10 3 0.3 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0051240 Not Cancer Driver No 90 0.208 35 7 0.2 4
ESRRG_ENST00000408911 ESRRG P62508 Estrogen-related receptor gamma chr1 GO:0051240 Not Cancer Driver No 135 0.295 76 29 0.382 0
ETV4_ENST00000591713 ETV4 P43268 ETS translocation variant 4 chr17 GO:0051240 Census, Compendium Yes 44 0.091 319 26 0.082 0
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 GO:0051240 Not Cancer Driver No 63 0.141 373 55 0.147 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0051240 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0051240 Not Cancer Driver No 3 0.011 102 0 0.0 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0051240 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0051240 Census Yes 66 0.113 295 35 0.119 0
F12 F12 P00748 Coagulation factor XII chr5 GO:0051240 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0051240 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0051240 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0051240 Not Cancer Driver No 55 0.139 7 2 0.286 0
F3 F3 P13726 Tissue factor chr1 GO:0051240 Not Cancer Driver No 28 0.095 61 7 0.115 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0051240 Not Cancer Driver No 74 0.159 50 7 0.14 108
FAAH FAAH O00519 Fatty-acid amide hydrolase 1 chr1 GO:0051240 Not Cancer Driver No 63 0.109 50 14 0.28 0
FABP4 FABP4 P15090 Fatty acid-binding protein, adipocyte chr8 GO:0051240 Not Cancer Driver No 14 0.106 4 0 0.0 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0051240 Not Cancer Driver No 15 0.111 4 4 1.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0051240 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0051240 Not Cancer Driver No 99 0.133 206 20 0.097 0
FAM173B ATPSCKMT Q6P4H8 ATP synthase subunit C lysine N-methyltransferase chr5 GO:0051240 Not Cancer Driver No 41 0.176 10 1 0.1 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 GO:0051240 Not Cancer Driver No 33 0.057 188 3 0.016 9
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0051240 Not Cancer Driver No 53 0.164 78 11 0.141 0
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0051240 Compendium Yes 607 0.208 135 24 0.178 30
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0051240 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0051240 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0051240 Not Cancer Driver No 68 0.114 120 4 0.033 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0051240 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0051240 Not Cancer Driver No 107 0.328 88 15 0.17 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0051240 Not Cancer Driver No 100 0.148 65 8 0.123 2
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0051240 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0051240 Census Yes 103 0.125 245 34 0.139 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0051240 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0051240 Not Cancer Driver No 78 0.225 29 6 0.207 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0051240 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0051240 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0051240 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0051240 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0051240 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0051240 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0051240 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0051240 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0051240 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0051240 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0051240 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0051240 Not Cancer Driver No 81 0.179 53 8 0.151 8
FH FH P07954 Fumarate hydratase, mitochondrial chr1 GO:0051240 Census, Compendium Yes 67 0.131 76 5 0.066 13
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0051240 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLRT2_ENST00000554746 FLRT2 O43155 Leucine-rich repeat transmembrane protein FLRT2 chr14 GO:0051240 Not Cancer Driver No 225 0.341 80 21 0.263 0
FLRT3_ENST00000341420 FLRT3 Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 chr20 GO:0051240 Not Cancer Driver No 108 0.166 112 15 0.134 4
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0051240 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:0051240 Compendium Yes 394 0.159 1243 185 0.149 8
FOS FOS P01100 Protein c-Fos chr14 GO:0051240 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0051240 Compendium Yes 70 0.153 258 34 0.132 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0051240 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0051240 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0051240 Not Cancer Driver No 10 0.022 259 5 0.019 0
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0051240 Not Cancer Driver No 132 0.27 322 79 0.245 2
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0051240 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0051240 Census, Compendium Yes 39 0.104 257 20 0.078 26
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0051240 Not Cancer Driver No 90 0.139 483 65 0.135 2
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0051240 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0051240 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0051240 Not Cancer Driver No 38 0.088 186 16 0.086 10
FOXS1 FOXS1 O43638 Forkhead box protein S1 chr20 GO:0051240 Not Cancer Driver No 67 0.203 226 41 0.181 0
FRMD8 FRMD8 Q9BZ67 FERM domain-containing protein 8 chr11 GO:0051240 Not Cancer Driver No 50 0.108 119 12 0.101 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0051240 Not Cancer Driver No 69 0.136 415 58 0.14 0
FST FST P19883 Follistatin chr5 GO:0051240 Not Cancer Driver No 50 0.145 20 7 0.35 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0051240 Not Cancer Driver No 93 0.117 283 35 0.124 0
FUT1_ENST00000645652 FUT1 P19526 Galactoside alpha-(1,2)-fucosyltransferase 1 chr19 GO:0051240 Not Cancer Driver No 63 0.173 17 3 0.176 0
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0051240 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0051240 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0051240 Not Cancer Driver No 55 0.093 61 0 0.0 0
G0S2 G0S2 P27469 G0/G1 switch protein 2 chr1 GO:0051240 Not Cancer Driver No 8 0.078 28 5 0.179 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0051240 Not Cancer Driver No 85 0.182 352 65 0.185 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:0051240 Not Cancer Driver No 13 0.082 20 2 0.1 0
GAL GAL P22466 Galanin peptides chr11 GO:0051240 Not Cancer Driver No 17 0.138 36 2 0.056 1
GALR1 GALR1 P47211 Galanin receptor type 1 chr18 GO:0051240 Not Cancer Driver No 68 0.195 32 2 0.062 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0051240 Not Cancer Driver No 39 0.116 24 3 0.125 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0051240 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0051240 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0051240 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0051240 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0051240 Not Cancer Driver No 57 0.096 476 51 0.107 10
GATM GATM P50440 Glycine amidinotransferase, mitochondrial chr15 GO:0051240 Not Cancer Driver No 69 0.163 33 8 0.242 15
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0051240 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBP5 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0051240 Not Cancer Driver No 106 0.181 170 21 0.124 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0051240 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0051240 Not Cancer Driver No 40 0.1 3 0 0.0 0
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0051240 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0051240 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0051240 Not Cancer Driver No 69 0.154 34 6 0.176 2
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0051240 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0051240 Not Cancer Driver No 65 0.15 288 42 0.146 62
GH1 GH1 P01241 Somatotropin chr17 GO:0051240 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0051240 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0051240 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0051240 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0051240 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0051240 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0051240 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0051240 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0051240 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0051240 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0051240 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0051240 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLIPR2 GLIPR2 Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 chr9 GO:0051240 Not Cancer Driver No 16 0.104 77 10 0.13 0
GLMN GLMN Q92990 Glomulin chr1 GO:0051240 Not Cancer Driver No 49 0.082 37 6 0.162 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0051240 Compendium Yes 50 0.141 24 0 0.0 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0051240 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0051240 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0051240 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:0051240 Not Cancer Driver No 26 0.141 82 15 0.183 10
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0051240 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPM6B_ENST00000356942 GPM6B Q13491 Neuronal membrane glycoprotein M6-b chrX GO:0051240 Not Cancer Driver No 39 0.147 14 3 0.214 0
GPR21 GPR21 Q99679 Probable G-protein coupled receptor 21 chr9 GO:0051240 Not Cancer Driver No 39 0.112 2 0 0.0 0
GPR3 GPR3 P46089 G-protein coupled receptor 3 chr1 GO:0051240 Not Cancer Driver No 38 0.115 13 1 0.077 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0051240 Not Cancer Driver No 42 0.115 45 1 0.022 1
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0051240 Not Cancer Driver No 82 0.203 75 19 0.253 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 GO:0051240 Not Cancer Driver No 26 0.163 160 26 0.163 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 GO:0051240 Not Cancer Driver No 94 0.158 220 38 0.173 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0051240 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0051240 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0051240 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSDMD_ENST00000262580 GSDMD P57764 Gasdermin-D chr8 GO:0051240 Not Cancer Driver No 47 0.097 156 16 0.103 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0051240 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0051240 Not Cancer Driver No 26 0.108 18 1 0.056 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0051240 Not Cancer Driver No 44 0.145 210 26 0.124 1
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0051240 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0051240 Not Cancer Driver No 59 0.159 171 32 0.187 0
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 GO:0051240 Not Cancer Driver No 33 0.105 22 5 0.227 3
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0051240 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0051240 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0051240 Not Cancer Driver No 97 0.145 454 60 0.132 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0051240 Not Cancer Driver No 69 0.229 17 2 0.118 3
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0051240 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0051240 Not Cancer Driver No 78 0.215 43 8 0.186 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0051240 Not Cancer Driver No 103 0.212 446 94 0.211 0
HCRT HCRT O43612 Orexin chr17 GO:0051240 Not Cancer Driver No 3 0.023 45 0 0.0 1
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0051240 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0051240 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0051240 Not Cancer Driver No 65 0.152 61 8 0.131 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0051240 Not Cancer Driver No 173 0.125 974 135 0.139 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0051240 Not Cancer Driver No 37 0.132 226 32 0.142 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0051240 Not Cancer Driver No 64 0.19 179 26 0.145 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0051240 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0051240 Census Yes 118 0.143 435 51 0.117 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0051240 Not Cancer Driver No 127 0.138 75 16 0.213 6
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0051240 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0051240 Not Cancer Driver No 37 0.142 30 4 0.133 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0051240 Not Cancer Driver No 38 0.147 39 4 0.103 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0051240 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0051240 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0051240 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0051240 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0051240 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0051240 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0051240 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0051240 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0051240 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMHB1 HMHB1 O97980 Minor histocompatibility protein HB-1 chr5 GO:0051240 Not Cancer Driver No 3 0.073 10 0 0.0 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0051240 Not Cancer Driver No 46 0.16 81 13 0.16 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0051240 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXB7 HOXB7 P09629 Homeobox protein Hox-B7 chr17 GO:0051240 Not Cancer Driver No 25 0.115 84 10 0.119 0
HOXC11 HOXC11 O43248 Homeobox protein Hox-C11 chr12 GO:0051240 Census Yes 35 0.115 157 16 0.102 0
HPSE HPSE Q9Y251 Heparanase chr4 GO:0051240 Not Cancer Driver No 90 0.166 16 2 0.125 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0051240 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRC HRC P23327 Sarcoplasmic reticulum histidine-rich calcium-binding protein chr19 GO:0051240 Not Cancer Driver No 110 0.157 612 98 0.16 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0051240 Not Cancer Driver No 121 0.23 277 75 0.271 2
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0051240 Not Cancer Driver No 96 0.197 122 26 0.213 0
HRH2_ENST00000231683 HRH2 P25021 Histamine H2 receptor chr5 GO:0051240 Not Cancer Driver No 84 0.234 44 6 0.136 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0051240 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0051240 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0051240 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0051240 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0051240 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0051240 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0051240 Not Cancer Driver No 105 0.223 44 8 0.182 0
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0051240 Not Cancer Driver No 52 0.11 8 1 0.125 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0051240 Not Cancer Driver No 14 0.104 52 7 0.135 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0051240 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0051240 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0051240 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFNG IFNG P01579 Interferon gamma chr12 GO:0051240 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0051240 Compendium Yes 55 0.112 175 22 0.126 10
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0051240 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0051240 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0051240 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0051240 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0051240 Not Cancer Driver No 61 0.159 245 40 0.163 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0051240 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0051240 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0051240 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0051240 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL12RB2 IL12RB2 Q99665 Interleukin-12 receptor subunit beta-2 chr1 GO:0051240 Not Cancer Driver No 129 0.15 195 31 0.159 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0051240 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL15RA_ENST00000379977 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 GO:0051240 Not Cancer Driver No 40 0.15 173 32 0.185 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0051240 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL16 IL16 Q14005 Pro-interleukin-16 chr15 GO:0051240 Not Cancer Driver No 216 0.162 959 151 0.157 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0051240 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17B IL17B Q9UHF5 Interleukin-17B chr5 GO:0051240 Not Cancer Driver No 29 0.161 48 10 0.208 0
IL17D IL17D Q8TAD2 Interleukin-17D chr13 GO:0051240 Not Cancer Driver No 9 0.045 64 1 0.016 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0051240 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 GO:0051240 Not Cancer Driver No 92 0.106 301 20 0.066 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0051240 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0051240 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0051240 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0051240 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0051240 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0051240 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL1RAP_ENST00000447382 IL1RAP Q9NPH3 Interleukin-1 receptor accessory protein chr3 GO:0051240 Not Cancer Driver No 79 0.139 50 11 0.22 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0051240 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL1RL2 IL1RL2 Q9HB29 Interleukin-1 receptor-like 2 chr2 GO:0051240 Not Cancer Driver No 114 0.198 11 4 0.364 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0051240 Census Yes 24 0.157 6 1 0.167 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0051240 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:0051240 Not Cancer Driver No 30 0.17 0 0 0.0 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0051240 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0051240 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0051240 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0051240 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0051240 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0051240 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0051240 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 GO:0051240 Not Cancer Driver No 44 0.278 13 3 0.231 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0051240 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0051240 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0051240 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0051240 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0051240 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0051240 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0051240 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0051240 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0051240 Census, Compendium Yes 177 0.386 88 48 0.545 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0051240 Not Cancer Driver No 12 0.083 4 0 0.0 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0051240 Not Cancer Driver No 112 0.169 553 98 0.177 1
INHA INHA P05111 Inhibin alpha chain chr2 GO:0051240 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0051240 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0051240 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0051240 Not Cancer Driver No 176 0.148 578 90 0.156 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0051240 Not Cancer Driver No 42 0.094 34 2 0.059 7
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0051240 Not Cancer Driver No 233 0.143 257 36 0.14 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0051240 Compendium Yes 71 0.1 337 39 0.116 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0051240 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0051240 Compendium Yes 49 0.151 228 31 0.136 2
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0051240 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0051240 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 GO:0051240 Not Cancer Driver No 93 0.187 237 64 0.27 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0051240 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0051240 Not Cancer Driver No 80 0.188 77 20 0.26 2
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0051240 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0051240 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISLR2_ENST00000565159 ISLR2 Q6UXK2 Immunoglobulin superfamily containing leucine-rich repeat protein 2 chr15 GO:0051240 Not Cancer Driver No 128 0.172 344 49 0.142 0
IST1_ENST00000541571 IST1 P53990 IST1 homolog chr16 GO:0051240 Not Cancer Driver No 31 0.085 185 17 0.092 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0051240 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0051240 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0051240 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGAX_ENST00000268296 ITGAX P20702 Integrin alpha-X chr16 GO:0051240 Not Cancer Driver No 245 0.211 82 15 0.183 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0051240 Not Cancer Driver No 28 0.061 216 7 0.032 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0051240 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0051240 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 GO:0051240 Census, Compendium Yes 147 0.127 120 7 0.058 2
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0051240 Census, Compendium Yes 136 0.12 59 5 0.085 5
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0051240 Not Cancer Driver No 291 0.214 1337 290 0.217 0
JMJD8_ENST00000609261 JMJD8 Q96S16 JmjC domain-containing protein 8 chr16 GO:0051240 Not Cancer Driver No 11 0.042 22 0 0.0 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0051240 Not Cancer Driver No 88 0.105 251 17 0.068 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0051240 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0051240 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0051240 Not Cancer Driver No 187 0.14 617 90 0.146 0
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0051240 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0051240 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:0051240 Not Cancer Driver No 189 0.115 1278 142 0.111 2
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0051240 Not Cancer Driver No 68 0.313 121 43 0.355 0
KISS1 KISS1 Q15726 Metastasis-suppressor KiSS-1 chr1 GO:0051240 Not Cancer Driver No 17 0.123 116 14 0.121 1
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0051240 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0051240 Not Cancer Driver No 48 0.176 61 9 0.148 1
KL KL Q9UEF7 Klotho chr13 GO:0051240 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 GO:0051240 Not Cancer Driver No 59 0.123 349 46 0.132 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0051240 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0051240 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0051240 Not Cancer Driver No 37 0.08 142 9 0.063 0
KPNA6 KPNA6 O60684 Importin subunit alpha-7 chr1 GO:0051240 Not Cancer Driver No 70 0.131 97 17 0.175 0
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 GO:0051240 Not Cancer Driver No 86 0.199 160 31 0.194 18
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 GO:0051240 Not Cancer Driver No 231 0.243 434 120 0.276 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX GO:0051240 Not Cancer Driver No 228 0.181 442 75 0.17 54
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 GO:0051240 Not Cancer Driver No 50 0.116 4 0 0.0 1
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0051240 Not Cancer Driver No 10 0.11 17 0 0.0 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0051240 Not Cancer Driver No 46 0.176 16 6 0.375 0
LBH LBH Q53QV2 Protein LBH chr2 GO:0051240 Not Cancer Driver No 15 0.143 72 10 0.139 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0051240 Not Cancer Driver No 84 0.175 6 0 0.0 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 GO:0051240 Not Cancer Driver No 29 0.146 4 3 0.75 0
LDLRAP1 LDLRAP1 Q5SW96 Low density lipoprotein receptor adapter protein 1 chr1 GO:0051240 Not Cancer Driver No 36 0.117 119 17 0.143 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0051240 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0051240 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0051240 Not Cancer Driver No 243 0.209 57 11 0.193 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0051240 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0051240 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0051240 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0051240 Not Cancer Driver No 108 0.114 16 3 0.188 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0051240 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0051240 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0051240 Not Cancer Driver No 79 0.264 98 19 0.194 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0051240 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0051240 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0051240 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0051240 Not Cancer Driver No 110 0.17 170 30 0.176 0
LINGO2_ENST00000308675 LINGO2 Q7L985 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 chr9 GO:0051240 Not Cancer Driver No 214 0.353 30 8 0.267 0
LIPG LIPG Q9Y5X9 Endothelial lipase chr18 GO:0051240 Not Cancer Driver No 90 0.18 59 7 0.119 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0051240 Not Cancer Driver No 99 0.177 456 84 0.184 1
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 GO:0051240 Not Cancer Driver No 134 0.173 39 4 0.103 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0051240 Not Cancer Driver No 65 0.184 9 0 0.0 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0051240 Not Cancer Driver No 54 0.111 1 0 0.0 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:0051240 Not Cancer Driver No 120 0.135 447 70 0.157 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0051240 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0051240 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0051240 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0051240 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 GO:0051240 Not Cancer Driver No 41 0.115 188 20 0.106 0
LRRC24 LRRC24 Q50LG9 Leucine-rich repeat-containing protein 24 chr8 GO:0051240 Not Cancer Driver No 32 0.062 131 13 0.099 0
LRRC4B_ENST00000389201 LRRC4B Q9NT99 Leucine-rich repeat-containing protein 4B chr19 GO:0051240 Not Cancer Driver No 141 0.198 245 46 0.188 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051240 Not Cancer Driver No 519 0.205 90 17 0.189 23
LRRN1 LRRN1 Q6UXK5 Leucine-rich repeat neuronal protein 1 chr3 GO:0051240 Not Cancer Driver No 140 0.196 18 5 0.278 0
LRRN3_ENST00000422987 LRRN3 Q9H3W5 Leucine-rich repeat neuronal protein 3 chr7 GO:0051240 Not Cancer Driver No 156 0.22 19 4 0.211 0
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 GO:0051240 Not Cancer Driver No 172 0.33 57 17 0.298 0
LRRTM2 LRRTM2 O43300 Leucine-rich repeat transmembrane neuronal protein 2 chr5 GO:0051240 Not Cancer Driver No 57 0.11 33 1 0.03 0
LRRTM3 LRRTM3 Q86VH5 Leucine-rich repeat transmembrane neuronal protein 3 chr10 GO:0051240 Not Cancer Driver No 142 0.244 136 31 0.228 0
LRTM2_ENST00000299194 LRTM2 Q8N967 Leucine-rich repeat and transmembrane domain-containing protein 2 chr12 GO:0051240 Not Cancer Driver No 81 0.219 77 19 0.247 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0051240 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTB LTB Q06643 Lymphotoxin-beta chr6 GO:0051240 Compendium Yes 33 0.135 91 13 0.143 0
LTF LTF P02788 Lactotransferrin chr3 GO:0051240 Not Cancer Driver No 131 0.185 21 4 0.19 0
LUM LUM P51884 Lumican chr12 GO:0051240 Not Cancer Driver No 108 0.32 1 0 0.0 0
LY9 LY9 Q9HBG7 T-lymphocyte surface antigen Ly-9 chr1 GO:0051240 Not Cancer Driver No 141 0.215 249 49 0.197 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0051240 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0051240 Census Yes 95 0.186 84 12 0.143 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0051240 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0051240 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX GO:0051240 Not Cancer Driver No 131 0.168 457 71 0.155 0
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0051240 Not Cancer Driver No 118 0.188 65 7 0.108 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0051240 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0051240 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0051240 Census Yes 157 0.163 593 91 0.153 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0051240 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0051240 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0051240 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0051240 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0051240 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0051240 Not Cancer Driver No 128 0.169 750 126 0.168 18
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0051240 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0051240 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCOLN2 MCOLN2 Q8IZK6 Mucolipin-2 chr1 GO:0051240 Not Cancer Driver No 93 0.164 0 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0051240 Not Cancer Driver No 15 0.105 20 2 0.1 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0051240 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 GO:0051240 Not Cancer Driver No 62 0.122 454 56 0.123 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0051240 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEFV MEFV O15553 Pyrin chr16 GO:0051240 Not Cancer Driver No 196 0.251 397 119 0.3 47
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0051240 Not Cancer Driver No 363 0.128 476 59 0.124 3
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0051240 Not Cancer Driver No 8 0.03 247 7 0.028 0
MFAP2 MFAP2 P55001 Microfibrillar-associated protein 2 chr1 GO:0051240 Not Cancer Driver No 19 0.104 72 11 0.153 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0051240 Not Cancer Driver No 80 0.106 81 9 0.111 20
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0051240 Not Cancer Driver No 4 0.035 0 0 0.0 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0051240 Not Cancer Driver No 56 0.098 6 1 0.167 22
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0051240 Census Yes 92 0.122 208 22 0.106 85
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0051240 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0051240 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0051240 Not Cancer Driver No 73 0.156 115 19 0.165 0
MMRN2 MMRN2 Q9H8L6 Multimerin-2 chr10 GO:0051240 Not Cancer Driver No 98 0.103 420 49 0.117 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0051240 Not Cancer Driver No 180 0.442 172 76 0.442 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:0051240 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0051240 Census Yes 92 0.099 37 4 0.108 70
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0051240 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTM1 MTM1 Q13496 Myotubularin chrX GO:0051240 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0051240 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0051240 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPN MTPN P58546 Myotrophin chr7 GO:0051240 Not Cancer Driver No 11 0.093 11 3 0.273 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0051240 Census Yes 82 0.128 528 69 0.131 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0051240 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0051240 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0051240 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0051240 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYMK MYMK A6NI61 Protein myomaker chr9 GO:0051240 Not Cancer Driver No 32 0.145 0 0 0.0 3
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0051240 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0051240 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0051240 Not Cancer Driver No 36 0.161 132 20 0.152 0
MYRF MYRF Q9Y2G1 Myelin regulatory factor chr11 GO:0051240 Not Cancer Driver No 103 0.089 684 70 0.102 2
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0051240 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCMAP NCMAP Q5T1S8 Noncompact myelin-associated protein chr1 GO:0051240 Not Cancer Driver No 17 0.167 43 8 0.186 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0051240 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0051240 Not Cancer Driver No 32 0.093 202 16 0.079 0
NELL1_ENST00000357134 NELL1 Q92832 Protein kinase C-binding protein NELL1 chr11 GO:0051240 Not Cancer Driver No 238 0.294 7 3 0.429 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0051240 Not Cancer Driver No 62 0.108 153 11 0.072 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0051240 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0051240 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0051240 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0051240 Not Cancer Driver No 96 0.134 443 53 0.12 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0051240 Not Cancer Driver No 66 0.274 93 25 0.269 1
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0051240 Not Cancer Driver No 57 0.133 172 25 0.145 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0051240 Compendium Yes 353 0.126 1528 184 0.12 37
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0051240 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0051240 Not Cancer Driver No 84 0.308 206 65 0.316 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0051240 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0051240 Not Cancer Driver No 35 0.15 171 16 0.094 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0051240 Not Cancer Driver No 38 0.104 325 34 0.105 0
NKX6-2 NKX6-2 Q9C056 Homeobox protein Nkx-6.2 chr10 GO:0051240 Not Cancer Driver No 27 0.097 137 23 0.168 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0051240 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0051240 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0051240 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0051240 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0051240 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0051240 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0051240 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP2 NLRP2 Q9NX02 NACHT, LRR and PYD domains-containing protein 2 chr19 GO:0051240 Not Cancer Driver No 257 0.242 60 15 0.25 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0051240 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP5 NLRP5 P59047 NACHT, LRR and PYD domains-containing protein 5 chr19 GO:0051240 Not Cancer Driver No 369 0.307 144 35 0.243 0
NLRP9 NLRP9 Q7RTR0 NACHT, LRR and PYD domains-containing protein 9 chr19 GO:0051240 Not Cancer Driver No 247 0.249 0 0 0.0 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0051240 Not Cancer Driver No 13 0.086 11 1 0.091 0
NMU NMU P48645 Neuromedin-U chr4 GO:0051240 Not Cancer Driver No 22 0.126 31 2 0.065 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0051240 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0051240 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0051240 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0051240 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0051240 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0051240 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0051240 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0051240 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPAS2 NPAS2 Q99743 Neuronal PAS domain-containing protein 2 chr2 GO:0051240 Not Cancer Driver No 114 0.138 465 65 0.14 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0051240 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0051240 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPPB NPPB P16860 Natriuretic peptides B chr1 GO:0051240 Not Cancer Driver No 31 0.231 104 28 0.269 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0051240 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPS NPS P0C0P6 Neuropeptide S chr10 GO:0051240 Not Cancer Driver No 27 0.303 5 2 0.4 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0051240 Not Cancer Driver No 47 0.118 118 9 0.076 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0051240 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0051240 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 GO:0051240 Not Cancer Driver No 62 0.104 186 24 0.129 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0051240 Census Yes 83 0.133 298 37 0.124 0
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0051240 Not Cancer Driver No 60 0.13 133 29 0.218 24
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0051240 Compendium Yes 146 0.158 211 31 0.147 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0051240 Not Cancer Driver No 593 0.401 301 110 0.365 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0051240 Census, Compendium Yes 191 0.14 552 76 0.138 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0051240 Not Cancer Driver No 57 0.094 66 4 0.061 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0051240 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0051240 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0051240 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0051240 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0051240 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS2 OAS2 P29728 2'-5'-oligoadenylate synthase 2 chr12 GO:0051240 Not Cancer Driver No 141 0.196 47 14 0.298 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0051240 Not Cancer Driver No 139 0.128 147 17 0.116 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 GO:0051240 Not Cancer Driver No 233 0.123 553 60 0.108 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0051240 Not Cancer Driver No 22 0.039 52 6 0.115 0
ODAPH_ENST00000311623 ODAPH Q17RF5 Odontogenesis associated phosphoprotein chr4 GO:0051240 Not Cancer Driver No 28 0.215 48 14 0.292 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0051240 Not Cancer Driver No 156 0.149 89 16 0.18 2
OLFM1 OLFM1 Q99784 Noelin chr9 GO:0051240 Not Cancer Driver No 88 0.181 83 10 0.12 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0051240 Census Yes 37 0.115 256 37 0.145 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 GO:0051240 Not Cancer Driver No 52 0.099 34 4 0.118 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0051240 Not Cancer Driver No 81 0.219 0 0 0.0 0
ORM1 ORM1 P02763 Alpha-1-acid glycoprotein 1 chr9 GO:0051240 Not Cancer Driver No 38 0.189 23 2 0.087 0
ORM2 ORM2 P19652 Alpha-1-acid glycoprotein 2 chr9 GO:0051240 Not Cancer Driver No 38 0.189 22 2 0.091 0
OSM OSM P13725 Oncostatin-M chr22 GO:0051240 Not Cancer Driver No 43 0.171 114 24 0.211 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0051240 Not Cancer Driver No 57 0.214 67 17 0.254 0
OSR2_ENST00000522510 OSR2 Q8N2R0 Protein odd-skipped-related 2 chr8 GO:0051240 Not Cancer Driver No 59 0.189 66 13 0.197 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0051240 Not Cancer Driver No 36 0.111 278 29 0.104 0
OTX2_ENST00000408990 OTX2 P32243 Homeobox protein OTX2 chr14 GO:0051240 Not Cancer Driver No 76 0.263 165 41 0.248 6
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0051240 Not Cancer Driver No 29 0.105 139 8 0.058 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0051240 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0051240 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0051240 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0051240 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0051240 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 GO:0051240 Not Cancer Driver No 67 0.178 60 13 0.217 0
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 GO:0051240 Not Cancer Driver No 23 0.128 3 0 0.0 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0051240 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0051240 Not Cancer Driver No 127 0.227 286 64 0.224 2
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0051240 Not Cancer Driver No 54 0.127 45 7 0.156 2
PANX2 PANX2 Q96RD6 Pannexin-2 chr22 GO:0051240 Not Cancer Driver No 73 0.108 293 14 0.048 0
PANX3 PANX3 Q96QZ0 Pannexin-3 chr11 GO:0051240 Not Cancer Driver No 92 0.235 10 4 0.4 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0051240 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0051240 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0051240 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0051240 Not Cancer Driver No 74 0.127 172 23 0.134 0
PARP6 PARP6 Q2NL67 Protein mono-ADP-ribosyltransferase PARP6 chr15 GO:0051240 Not Cancer Driver No 87 0.138 67 13 0.194 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0051240 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0051240 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0051240 Census Yes 84 0.187 291 55 0.189 4
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0051240 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0051240 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0051240 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0051240 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0051240 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0051240 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDE9A PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0051240 Not Cancer Driver No 91 0.153 160 34 0.212 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0051240 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0051240 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0051240 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0051240 Not Cancer Driver No 37 0.228 96 24 0.25 0
PEMT_ENST00000395783 PEMT Q9UBM1 Phosphatidylethanolamine N-methyltransferase chr17 GO:0051240 Not Cancer Driver No 21 0.106 1 0 0.0 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0051240 Not Cancer Driver No 109 0.408 142 62 0.437 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0051240 Not Cancer Driver No 166 0.132 782 101 0.129 1
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 GO:0051240 Not Cancer Driver No 73 0.114 321 36 0.112 2
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0051240 Not Cancer Driver No 13 0.129 0 0 0.0 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0051240 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHOX2B PHOX2B Q99453 Paired mesoderm homeobox protein 2B chr4 GO:0051240 Census Yes 59 0.188 219 44 0.201 2
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0051240 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0051240 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0051240 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0051240 Census, Compendium Yes 71 0.227 27 8 0.296 0
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0051240 Not Cancer Driver No 36 0.073 124 0 0.0 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0051240 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0051240 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0051240 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLAC8_ENST00000505406 PLAC8 Q9NZF1 Placenta-specific gene 8 protein chr4 GO:0051240 Not Cancer Driver No 20 0.174 7 0 0.0 0
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0051240 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0051240 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0051240 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0051240 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLG PLG P00747 Plasminogen chr6 GO:0051240 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLS1 PLS1 Q14651 Plastin-1 chr3 GO:0051240 Not Cancer Driver No 100 0.159 59 8 0.136 4
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0051240 Not Cancer Driver No 38 0.131 29 2 0.069 5
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 GO:0051240 Not Cancer Driver No 155 0.112 113 17 0.15 15
POLR3B POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 GO:0051240 Not Cancer Driver No 164 0.145 117 20 0.171 8
POLR3C POLR3C Q9BUI4 DNA-directed RNA polymerase III subunit RPC3 chr1 GO:0051240 Not Cancer Driver No 60 0.112 161 21 0.13 0
POLR3D POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 GO:0051240 Not Cancer Driver No 33 0.083 303 24 0.079 0
POLR3F POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:0051240 Not Cancer Driver No 20 0.063 55 5 0.091 0
POLR3G POLR3G O15318 DNA-directed RNA polymerase III subunit RPC7 chr5 GO:0051240 Not Cancer Driver No 28 0.126 187 15 0.08 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0051240 Not Cancer Driver No 62 0.092 93 4 0.043 9
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 GO:0051240 Census Yes 59 0.23 181 45 0.249 0
POU2F2 POU2F2 P09086 POU domain, class 2, transcription factor 2 chr19 GO:0051240 Compendium Yes 82 0.171 387 67 0.173 0
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0051240 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0051240 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0051240 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0051240 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0051240 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0051240 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 GO:0051240 Not Cancer Driver No 28 0.13 16 1 0.062 1
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0051240 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0051240 Not Cancer Driver No 44 0.097 30 3 0.1 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0051240 Compendium Yes 85 0.163 140 27 0.193 7
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0051240 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0051240 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRDM14 PRDM14 Q9GZV8 PR domain zinc finger protein 14 chr8 GO:0051240 Not Cancer Driver No 122 0.214 179 37 0.207 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 GO:0051240 Census Yes 254 0.199 830 152 0.183 1
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0051240 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRG3 PRG3 Q9Y2Y8 Proteoglycan 3 chr11 GO:0051240 Not Cancer Driver No 40 0.178 60 12 0.2 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0051240 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 GO:0051240 Not Cancer Driver No 39 0.144 124 13 0.105 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 GO:0051240 Not Cancer Driver No 31 0.114 110 12 0.109 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0051240 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0051240 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0051240 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0051240 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0051240 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0051240 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0051240 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0051240 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRL PRL P01236 Prolactin chr6 GO:0051240 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0051240 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0051240 Not Cancer Driver No 83 0.13 72 6 0.083 0
PROK2 PROK2 Q9HC23 Prokineticin-2 chr3 GO:0051240 Not Cancer Driver No 18 0.14 23 1 0.043 6
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0051240 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0051240 Not Cancer Driver No 71 0.141 109 16 0.147 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0051240 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0051240 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 GO:0051240 Not Cancer Driver No 79 0.203 17 2 0.118 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0051240 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0051240 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTH2R PTH2R P49190 Parathyroid hormone 2 receptor chr2 GO:0051240 Not Cancer Driver No 123 0.224 49 17 0.347 0
PTN PTN P21246 Pleiotrophin chr7 GO:0051240 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0051240 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0051240 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0051240 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0051240 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0051240 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0051240 Not Cancer Driver No 480 0.207 978 216 0.221 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0051240 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYDC1 PYDC1 Q8WXC3 Pyrin domain-containing protein 1 chr16 GO:0051240 Not Cancer Driver No 28 0.315 0 0 0.0 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0051240 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0051240 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0051240 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0051240 Not Cancer Driver No 23 0.102 59 4 0.068 0
RAB8B RAB8B Q92930 Ras-related protein Rab-8B chr15 GO:0051240 Not Cancer Driver No 22 0.106 29 2 0.069 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0051240 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0051240 Not Cancer Driver No 41 0.123 62 10 0.161 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0051240 Not Cancer Driver No 118 0.224 85 23 0.271 6
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0051240 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0051240 Not Cancer Driver No 25 0.152 7 1 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0051240 Not Cancer Driver No 96 0.12 191 12 0.063 1
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0051240 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBM19 RBM19 Q9Y4C8 Probable RNA-binding protein 19 chr12 GO:0051240 Not Cancer Driver No 146 0.152 514 76 0.148 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0051240 Not Cancer Driver No 49 0.098 151 19 0.126 2
RELA RELA Q04206 Transcription factor p65 chr11 GO:0051240 Compendium Yes 75 0.136 400 48 0.12 0
RELN RELN P78509 Reelin chr7 GO:0051240 Not Cancer Driver No 761 0.22 107 19 0.178 7
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0051240 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0051240 Census, Compendium Yes 208 0.187 105 12 0.114 139
RETN RETN Q9HD89 Resistin chr19 GO:0051240 Not Cancer Driver No 10 0.093 0 0 0.0 0
RFTN1 RFTN1 Q14699 Raftlin chr3 GO:0051240 Not Cancer Driver No 87 0.151 319 44 0.138 0
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 GO:0051240 Not Cancer Driver No 113 0.151 308 41 0.133 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0051240 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0051240 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0051240 Not Cancer Driver No 68 0.332 5 4 0.8 0
RHEB RHEB Q15382 GTP-binding protein Rheb chr7 GO:0051240 Not Cancer Driver No 30 0.163 0 0 0.0 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0051240 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0051240 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0051240 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0051240 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0051240 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0051240 Not Cancer Driver No 63 0.117 143 20 0.14 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0051240 Not Cancer Driver No 19 0.084 54 4 0.074 0
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 GO:0051240 Not Cancer Driver No 108 0.133 455 63 0.138 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0051240 Not Cancer Driver No 86 0.136 168 26 0.155 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0051240 Not Cancer Driver No 40 0.093 139 11 0.079 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0051240 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0051240 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0051240 Not Cancer Driver No 203 0.215 299 71 0.237 5
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0051240 Not Cancer Driver No 57 0.109 182 17 0.093 4
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0051240 Not Cancer Driver No 15 0.103 61 3 0.049 23
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0051240 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0051240 Not Cancer Driver No 45 0.086 226 26 0.115 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0051240 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0051240 Not Cancer Driver No 68 0.188 22 1 0.045 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0051240 Not Cancer Driver No 121 0.102 866 82 0.095 0
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0051240 Not Cancer Driver No 75 0.16 204 29 0.142 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0051240 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0051240 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0051240 Not Cancer Driver No 59 0.142 331 45 0.136 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0051240 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S100A1 S100A1 P23297 Protein S100-A1 chr1 GO:0051240 Not Cancer Driver No 13 0.138 9 0 0.0 0
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0051240 Not Cancer Driver No 12 0.122 6 0 0.0 0
SAA1 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0051240 Not Cancer Driver No 23 0.189 25 5 0.2 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0051240 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0051240 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCD SCD O00767 Stearoyl-CoA desaturase chr10 GO:0051240 Not Cancer Driver No 36 0.1 18 0 0.0 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0051240 Not Cancer Driver No 10 0.069 73 9 0.123 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 GO:0051240 Not Cancer Driver No 63 0.293 16 5 0.312 3
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0051240 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SCT SCT P09683 Secretin chr11 GO:0051240 Not Cancer Driver No 4 0.033 71 3 0.042 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0051240 Not Cancer Driver No 39 0.131 17 2 0.118 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0051240 Not Cancer Driver No 10 0.106 47 6 0.128 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0051240 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0051240 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0051240 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0051240 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0051240 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERP1_ENST00000239944 SERP1 Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 chr3 GO:0051240 Not Cancer Driver No 6 0.091 30 2 0.067 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0051240 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINB7 SERPINB7 O75635 Serpin B7 chr18 GO:0051240 Not Cancer Driver No 100 0.263 30 8 0.267 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0051240 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0051240 Not Cancer Driver No 62 0.156 0 0 0.0 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0051240 Not Cancer Driver No 62 0.126 112 21 0.188 1
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0051240 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SETD4 SETD4 Q9NVD3 SET domain-containing protein 4 chr21 GO:0051240 Not Cancer Driver No 51 0.116 27 2 0.074 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0051240 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0051240 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0051240 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0051240 Not Cancer Driver No 3 0.012 81 1 0.012 0
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0051240 Not Cancer Driver No 67 0.202 200 40 0.2 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0051240 Census Yes 68 0.108 470 52 0.111 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0051240 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0051240 Not Cancer Driver No 33 0.093 164 12 0.073 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0051240 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0051240 Not Cancer Driver No 99 0.127 460 58 0.126 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0051240 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF6 SLAMF6 Q96DU3 SLAM family member 6 chr1 GO:0051240 Not Cancer Driver No 69 0.208 60 14 0.233 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0051240 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0051240 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC22A5_ENST00000245407 SLC22A5 O76082 Solute carrier family 22 member 5 chr5 GO:0051240 Not Cancer Driver No 53 0.095 15 2 0.133 73
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0051240 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0051240 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC39A12 SLC39A12 Q504Y0 Zinc transporter ZIP12 chr10 GO:0051240 Not Cancer Driver No 210 0.304 89 29 0.326 0
SLC4A2 SLC4A2 P04920 Anion exchange protein 2 chr7 GO:0051240 Not Cancer Driver No 150 0.121 509 62 0.122 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0051240 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 GO:0051240 Not Cancer Driver No 62 0.122 35 1 0.029 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0051240 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0051240 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0051240 Not Cancer Driver No 68 0.127 80 16 0.2 0
SLITRK1 SLITRK1 Q96PX8 SLIT and NTRK-like protein 1 chr13 GO:0051240 Not Cancer Driver No 299 0.43 126 64 0.508 0
SLITRK2 SLITRK2 Q9H156 SLIT and NTRK-like protein 2 chrX GO:0051240 Not Cancer Driver No 276 0.327 244 91 0.373 0
SLITRK3 SLITRK3 O94933 SLIT and NTRK-like protein 3 chr3 GO:0051240 Not Cancer Driver No 335 0.343 321 127 0.396 0
SLITRK4_ENST00000338017 SLITRK4 Q8IW52 SLIT and NTRK-like protein 4 chrX GO:0051240 Not Cancer Driver No 257 0.307 172 45 0.262 0
SLITRK5 SLITRK5 O94991 SLIT and NTRK-like protein 5 chr13 GO:0051240 Not Cancer Driver No 257 0.268 346 93 0.269 0
SLITRK6_ENST00000643778 SLITRK6 Q9H5Y7 SLIT and NTRK-like protein 6 chr13 GO:0051240 Not Cancer Driver No 244 0.29 225 53 0.236 0
SLN_ENST00000525934 SLN O00631 Sarcolipin chr11 GO:0051240 Not Cancer Driver No 8 0.258 0 0 0.0 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0051240 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0051240 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0051240 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0051240 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0051240 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:0051240 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0051240 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0051240 Not Cancer Driver No 82 0.184 216 52 0.241 0
SMTNL1 SMTNL1 A8MU46 Smoothelin-like protein 1 chr11 GO:0051240 Not Cancer Driver No 80 0.162 372 54 0.145 0
SMTNL2 SMTNL2 Q2TAL5 Smoothelin-like protein 2 chr17 GO:0051240 Not Cancer Driver No 45 0.098 344 33 0.096 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0051240 Not Cancer Driver No 87 0.116 242 28 0.116 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0051240 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0051240 Not Cancer Driver No 31 0.069 101 5 0.05 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0051240 Not Cancer Driver No 33 0.082 91 13 0.143 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0051240 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0051240 Not Cancer Driver No 84 0.157 297 46 0.155 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0051240 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0051240 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0051240 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:0051240 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0051240 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0051240 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 GO:0051240 Not Cancer Driver No 182 0.239 665 162 0.244 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 GO:0051240 Not Cancer Driver No 130 0.157 744 118 0.159 0
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0051240 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0051240 Compendium Yes 86 0.169 495 82 0.166 18
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0051240 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0051240 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0051240 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPINT1 SPINT1 O43278 Kunitz-type protease inhibitor 1 chr15 GO:0051240 Not Cancer Driver No 63 0.119 75 12 0.16 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0051240 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0051240 Not Cancer Driver No 36 0.109 73 4 0.055 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0051240 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0051240 Not Cancer Driver No 311 0.132 869 123 0.142 0
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0051240 Not Cancer Driver No 312 0.122 866 103 0.119 0
SPX SPX Q9BT56 Spexin chr12 GO:0051240 Not Cancer Driver No 22 0.19 40 8 0.2 0
SRF SRF P11831 Serum response factor chr6 GO:0051240 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0051240 Not Cancer Driver No 86 0.185 64 13 0.203 0
SRY SRY Q05066 Sex-determining region Y protein chrY GO:0051240 Not Cancer Driver No 8 0.039 105 2 0.019 27
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:0051240 Census Yes 53 0.134 356 48 0.135 0
SS18L2 SS18L2 Q9UHA2 SS18-like protein 2 chr3 GO:0051240 Not Cancer Driver No 4 0.052 7 1 0.143 0
ST3GAL4_ENST00000534083 ST3GAL4 Q11206 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 chr11 GO:0051240 Not Cancer Driver No 31 0.093 3 2 0.667 0
ST8SIA2 ST8SIA2 Q92186 Alpha-2,8-sialyltransferase 8B chr15 GO:0051240 Not Cancer Driver No 84 0.224 38 8 0.211 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0051240 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0051240 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0051240 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0051240 Census, Compendium Yes 106 0.125 325 44 0.135 0
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0051240 Not Cancer Driver No 68 0.119 486 54 0.111 0
STMP1 STMP1 E0CX11 Short transmembrane mitochondrial protein 1 chr7 GO:0051240 Not Cancer Driver No 1 0.021 12 0 0.0 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0051240 Not Cancer Driver No 40 0.112 117 9 0.077 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0051240 Not Cancer Driver No 121 0.122 659 83 0.126 2
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0051240 Not Cancer Driver No 246 0.282 269 71 0.264 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 GO:0051240 Not Cancer Driver No 145 0.167 142 18 0.127 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 GO:0051240 Not Cancer Driver No 62 0.084 412 27 0.066 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0051240 Census Yes 96 0.151 131 27 0.206 5
SYNDIG1 SYNDIG1 Q9H7V2 Synapse differentiation-inducing gene protein 1 chr20 GO:0051240 Not Cancer Driver No 90 0.349 110 40 0.364 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0051240 Not Cancer Driver No 208 0.132 584 76 0.13 3
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0051240 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACR2 TACR2 P21452 Substance-K receptor chr10 GO:0051240 Not Cancer Driver No 61 0.153 11 4 0.364 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 GO:0051240 Not Cancer Driver No 137 0.295 31 17 0.548 5
TAPT1 TAPT1 Q6NXT6 Transmembrane anterior posterior transformation protein 1 homolog chr4 GO:0051240 Not Cancer Driver No 47 0.083 131 12 0.092 1
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0051240 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0051240 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0051240 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0051240 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0051240 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0051240 Not Cancer Driver No 47 0.137 17 4 0.235 1
TBXAS1_ENST00000448866 TBXAS1 P24557 Thromboxane-A synthase chr7 GO:0051240 Not Cancer Driver No 116 0.218 44 8 0.182 4
TEAD4 TEAD4 Q15561 Transcriptional enhancer factor TEF-3 chr12 GO:0051240 Not Cancer Driver No 72 0.166 171 34 0.199 0
TENM4 TENM4 Q6N022 Teneurin-4 chr11 GO:0051240 Not Cancer Driver No 492 0.178 498 63 0.127 3
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 GO:0051240 Not Cancer Driver No 43 0.097 0 0 0.0 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0051240 Census Yes 110 0.097 212 16 0.075 31
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0051240 Not Cancer Driver No 31 0.145 73 6 0.082 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0051240 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0051240 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0051240 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0051240 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0051240 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0051240 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0051240 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0051240 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0051240 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0051240 Not Cancer Driver No 129 0.152 268 41 0.153 0
THBD THBD P07204 Thrombomodulin chr20 GO:0051240 Not Cancer Driver No 39 0.068 51 3 0.059 9
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0051240 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS2 THBS2 P35442 Thrombospondin-2 chr6 GO:0051240 Not Cancer Driver No 246 0.21 319 68 0.213 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0051240 Not Cancer Driver No 69 0.141 207 30 0.145 2
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0051240 Not Cancer Driver No 370 0.233 810 194 0.24 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0051240 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIGIT TIGIT Q495A1 T-cell immunoreceptor with Ig and ITIM domains chr3 GO:0051240 Not Cancer Driver No 60 0.246 28 4 0.143 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0051240 Not Cancer Driver No 28 0.127 80 6 0.075 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0051240 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TLE6 TLE6 Q9H808 Transducin-like enhancer protein 6 chr19 GO:0051240 Not Cancer Driver No 89 0.156 227 31 0.137 1
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0051240 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0051240 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0051240 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0051240 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0051240 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0051240 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0051240 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0051240 Not Cancer Driver No 180 0.173 30 7 0.233 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0051240 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMBIM1_ENST00000396809 TMBIM1 Q969X1 Protein lifeguard 3 chr2 GO:0051240 Not Cancer Driver No 30 0.096 83 8 0.096 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 GO:0051240 Not Cancer Driver No 24 0.11 15 3 0.2 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0051240 Not Cancer Driver No 26 0.099 9 1 0.111 0
TMEM119 TMEM119 Q4V9L6 Transmembrane protein 119 chr12 GO:0051240 Not Cancer Driver No 59 0.208 195 47 0.241 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0051240 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM64 TMEM64 Q6YI46 Transmembrane protein 64 chr8 GO:0051240 Not Cancer Driver No 33 0.087 32 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051240 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0051240 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0051240 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0051240 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFRSF8 TNFRSF8 P28908 Tumor necrosis factor receptor superfamily member 8 chr1 GO:0051240 Not Cancer Driver No 95 0.16 286 35 0.122 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0051240 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0051240 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0051240 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0051240 Not Cancer Driver No 32 0.126 39 4 0.103 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0051240 Not Cancer Driver No 426 0.328 637 231 0.363 0
TNR TNR Q92752 Tenascin-R chr1 GO:0051240 Not Cancer Driver No 496 0.365 358 128 0.358 0
TOB2 TOB2 Q14106 Protein Tob2 chr22 GO:0051240 Not Cancer Driver No 36 0.105 147 16 0.109 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0051240 Not Cancer Driver No 59 0.097 140 8 0.057 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0051240 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0051240 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0051240 Census, Compendium Yes 229 0.337 398 143 0.359 28
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0051240 Not Cancer Driver No 82 0.129 443 55 0.124 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0051240 Not Cancer Driver No 58 0.138 13 1 0.077 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0051240 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPPP TPPP O94811 Tubulin polymerization-promoting protein chr5 GO:0051240 Not Cancer Driver No 33 0.151 149 21 0.141 0
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0051240 Not Cancer Driver No 26 0.083 74 5 0.068 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0051240 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0051240 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0051240 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0051240 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0051240 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0051240 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0051240 Census Yes 59 0.115 87 11 0.126 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0051240 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0051240 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0051240 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0051240 Not Cancer Driver No 200 0.239 23 2 0.087 1
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0051240 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0051240 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPM8 TRPM8 Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 chr2 GO:0051240 Not Cancer Driver No 206 0.187 43 11 0.256 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0051240 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0051240 Not Cancer Driver No 105 0.137 175 23 0.131 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0051240 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0051240 Census Yes 128 0.168 38 9 0.237 39
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0051240 Not Cancer Driver No 53 0.15 44 6 0.136 0
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0051240 Not Cancer Driver No 27 0.17 16 0 0.0 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0051240 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0051240 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTPA TTPA P49638 Alpha-tocopherol transfer protein chr8 GO:0051240 Not Cancer Driver No 53 0.191 20 1 0.05 7
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0051240 Not Cancer Driver No 10 0.091 31 3 0.097 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0051240 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0051240 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0051240 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0051240 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0051240 Not Cancer Driver No 148 0.125 213 29 0.136 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0051240 Not Cancer Driver No 24 0.212 28 8 0.286 0
UCN UCN P55089 Urocortin chr2 GO:0051240 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0051240 Not Cancer Driver No 43 0.14 1 0 0.0 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0051240 Not Cancer Driver No 31 0.1 11 3 0.273 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0051240 Not Cancer Driver No 109 0.137 141 24 0.17 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0051240 Not Cancer Driver No 214 0.135 448 77 0.172 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0051240 Not Cancer Driver No 52 0.168 271 44 0.162 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 GO:0051240 Not Cancer Driver No 33 0.097 2 0 0.0 0
UTP25 UTP25 Q68CQ4 U3 small nucleolar RNA-associated protein 25 homolog chr1 GO:0051240 Not Cancer Driver No 116 0.153 277 28 0.101 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0051240 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0051240 Not Cancer Driver No 9 0.09 27 0 0.0 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0051240 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0051240 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0051240 Not Cancer Driver No 128 0.305 37 12 0.324 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0051240 Not Cancer Driver No 124 0.15 222 38 0.171 0
VIP VIP P01282 VIP peptides chr6 GO:0051240 Not Cancer Driver No 58 0.341 77 25 0.325 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0051240 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0051240 Not Cancer Driver No 52 0.167 135 19 0.141 0
VSTM5 VSTM5 A8MXK1 V-set and transmembrane domain-containing protein 5 chr11 GO:0051240 Not Cancer Driver No 8 0.04 7 1 0.143 0
VTCN1 VTCN1 Q7Z7D3 V-set domain-containing T-cell activation inhibitor 1 chr1 GO:0051240 Not Cancer Driver No 43 0.152 3 2 0.667 0
WASF3 WASF3 Q9UPY6 Wiskott-Aldrich syndrome protein family member 3 chr13 GO:0051240 Not Cancer Driver No 108 0.215 386 84 0.218 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0051240 Not Cancer Driver No 181 0.119 792 100 0.126 5
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0051240 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0051240 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0051240 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0051240 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT2B WNT2B Q93097 Protein Wnt-2b chr1 GO:0051240 Not Cancer Driver No 72 0.184 27 3 0.111 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0051240 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0051240 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0051240 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0051240 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0051240 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0051240 Not Cancer Driver No 93 0.266 18 9 0.5 4
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0051240 Census Yes 41 0.102 387 41 0.106 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0051240 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0051240 Not Cancer Driver No 28 0.246 35 11 0.314 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0051240 Not Cancer Driver No 66 0.108 140 12 0.086 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0051240 Not Cancer Driver No 51 0.101 489 49 0.1 0
YBX2 YBX2 Q9Y2T7 Y-box-binding protein 2 chr17 GO:0051240 Not Cancer Driver No 48 0.132 342 46 0.135 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0051240 Not Cancer Driver No 49 0.132 359 47 0.131 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0051240 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBED2 ZBED2 Q9BTP6 Zinc finger BED domain-containing protein 2 chr3 GO:0051240 Not Cancer Driver No 62 0.284 172 39 0.227 0
ZBED3 ZBED3 Q96IU2 Zinc finger BED domain-containing protein 3 chr5 GO:0051240 Not Cancer Driver No 2 0.009 229 2 0.009 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0051240 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0051240 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0051240 Compendium Yes 151 0.204 433 80 0.185 4
ZBTB46_ENST00000302995 ZBTB46 Q86UZ6 Zinc finger and BTB domain-containing protein 46 chr20 GO:0051240 Not Cancer Driver No 115 0.195 301 68 0.226 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0051240 Compendium Yes 103 0.191 353 70 0.198 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0051240 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0051240 Compendium Yes 57 0.169 212 30 0.142 0
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:0051240 Not Cancer Driver No 50 0.05 772 27 0.035 0
ZFPM2 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 GO:0051240 Not Cancer Driver No 374 0.325 659 233 0.354 8
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 GO:0051240 Not Cancer Driver No 45 0.109 140 22 0.157 1
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 GO:0051240 Not Cancer Driver No 44 0.061 628 37 0.059 0
ZNF322_ENST00000607204 ZNF322 Q6U7Q0 Zinc finger protein 322 chr6 GO:0051240 Not Cancer Driver No 33 0.082 23 3 0.13 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0051240 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZNF516 ZNF516 Q92618 Zinc finger protein 516 chr18 GO:0051240 Not Cancer Driver No 177 0.152 861 131 0.152 0
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0051240 Not Cancer Driver No 8 0.047 153 8 0.052 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0051240 Not Cancer Driver No 26 0.044 415 14 0.034 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0051240 Not Cancer Driver No 55 0.13 56 11 0.196 1