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Total number of protein in "GO:0045321" GO term:  328

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0045321 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADA ADA P00813 Adenosine deaminase chr20 GO:0045321 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0045321 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0045321 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0045321 Not Cancer Driver No 86 0.105 129 13 0.101 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0045321 Not Cancer Driver No 31 0.077 297 21 0.071 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0045321 Not Cancer Driver No 56 0.283 0 0 0.0 8
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0045321 Not Cancer Driver No 14 0.095 61 6 0.098 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0045321 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0045321 Not Cancer Driver No 53 0.164 22 4 0.182 0
APBB1IP APBB1IP Q7Z5R6 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein chr10 GO:0045321 Not Cancer Driver No 130 0.195 396 60 0.152 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0045321 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0045321 Not Cancer Driver No 135 0.144 267 41 0.154 17
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0045321 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0045321 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0045321 Not Cancer Driver No 228 0.152 171 46 0.269 52
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0045321 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZI2 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 GO:0045321 Not Cancer Driver No 31 0.079 192 13 0.068 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0045321 Not Cancer Driver No 42 0.167 53 13 0.245 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0045321 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0045321 Not Cancer Driver No 98 0.087 861 79 0.092 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0045321 Not Cancer Driver No 28 0.224 119 25 0.21 0
BATF2 BATF2 Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 chr11 GO:0045321 Not Cancer Driver No 28 0.102 202 19 0.094 0
BATF3 BATF3 Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 chr1 GO:0045321 Not Cancer Driver No 18 0.142 127 18 0.142 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0045321 Census Yes 30 0.156 39 2 0.051 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0045321 Census, Compendium Yes 156 0.174 699 114 0.163 2
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0045321 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0045321 Census Yes 44 0.097 259 23 0.089 0
BTN3A1 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0045321 Not Cancer Driver No 77 0.15 72 18 0.25 0
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0045321 Not Cancer Driver No 16 0.06 84 3 0.036 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0045321 Not Cancer Driver No 41 0.167 124 16 0.129 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0045321 Not Cancer Driver No 71 0.203 0 0 0.0 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0045321 Not Cancer Driver No 106 0.24 103 28 0.272 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0045321 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0045321 Not Cancer Driver No 25 0.147 48 4 0.083 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0045321 Census, Compendium Yes 142 0.296 106 12 0.113 1
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0045321 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0045321 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR9 CCR9 P51686 C-C chemokine receptor type 9 chr3 GO:0045321 Not Cancer Driver No 60 0.163 0 0 0.0 0
CD180 CD180 Q99467 CD180 antigen chr5 GO:0045321 Not Cancer Driver No 105 0.159 0 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0045321 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0045321 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0045321 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0045321 Census Yes 42 0.191 18 10 0.556 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0045321 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD8A_ENST00000283635 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 GO:0045321 Not Cancer Driver No 33 0.14 28 2 0.071 1
CD93 CD93 Q9NPY3 Complement component C1q receptor chr20 GO:0045321 Not Cancer Driver No 145 0.222 195 49 0.251 0
CDH17 CDH17 Q12864 Cadherin-17 chr8 GO:0045321 Census Yes 166 0.2 186 35 0.188 0
CDH26 CDH26 Q8IXH8 Cadherin-like protein 26 chr20 GO:0045321 Not Cancer Driver No 157 0.189 296 48 0.162 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0045321 Census Yes 40 0.123 24 3 0.125 1
CHGA CHGA P10645 Chromogranin-A chr14 GO:0045321 Not Cancer Driver No 46 0.101 421 44 0.105 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 GO:0045321 Not Cancer Driver No 35 0.148 22 4 0.182 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0045321 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0045321 Not Cancer Driver No 56 0.256 5 2 0.4 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0045321 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0045321 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMTM7 CMTM7 Q96FZ5 CKLF-like MARVEL transmembrane domain-containing protein 7 chr3 GO:0045321 Not Cancer Driver No 25 0.143 0 0 0.0 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0045321 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPLX2_ENST00000515094 CPLX2 Q6PUV4 Complexin-2 chr5 GO:0045321 Not Cancer Driver No 27 0.201 134 27 0.201 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0045321 Not Cancer Driver No 88 0.12 436 60 0.138 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0045321 Not Cancer Driver No 64 0.163 135 14 0.104 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 GO:0045321 Census Yes 70 0.113 608 68 0.112 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0045321 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0045321 Not Cancer Driver No 11 0.076 34 3 0.088 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0045321 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSG CTSG P08311 Cathepsin G chr14 GO:0045321 Not Cancer Driver No 65 0.255 80 29 0.362 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0045321 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0045321 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 GO:0045321 Not Cancer Driver No 51 0.14 98 19 0.194 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0045321 Not Cancer Driver No 17 0.149 9 1 0.111 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0045321 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0045321 Not Cancer Driver No 87 0.242 8 0 0.0 0
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0045321 Compendium Yes 150 0.319 6 3 0.5 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0045321 Not Cancer Driver No 47 0.168 0 0 0.0 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0045321 Not Cancer Driver No 115 0.159 145 24 0.166 1
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0045321 Not Cancer Driver No 50 0.104 152 21 0.138 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0045321 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0045321 Not Cancer Driver No 24 0.085 0 0 0.0 0
DOCK10 DOCK10 Q96BY6 Dedicator of cytokinesis protein 10 chr2 GO:0045321 Not Cancer Driver No 368 0.168 409 58 0.142 0
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX GO:0045321 Not Cancer Driver No 312 0.151 240 29 0.121 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 GO:0045321 Not Cancer Driver No 480 0.262 266 79 0.297 2
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0045321 Not Cancer Driver No 321 0.153 312 60 0.192 1
DYSF_ENST00000258104 DYSF O75923 Dysferlin chr2 GO:0045321 Not Cancer Driver No 467 0.225 329 64 0.195 55
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0045321 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0045321 Not Cancer Driver No 21 0.118 87 13 0.149 0
ELF4 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX GO:0045321 Census, Compendium Yes 88 0.133 486 60 0.123 0
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0045321 Not Cancer Driver No 146 0.167 57 12 0.211 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0045321 Not Cancer Driver No 90 0.149 26 3 0.115 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0045321 Not Cancer Driver No 82 0.12 436 50 0.115 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0045321 Not Cancer Driver No 42 0.141 105 14 0.133 1
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0045321 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0045321 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0045321 Not Cancer Driver No 3 0.011 102 0 0.0 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0045321 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0045321 Not Cancer Driver No 26 0.125 45 10 0.222 1
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0045321 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0045321 Census Yes 51 0.165 99 30 0.303 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0045321 Not Cancer Driver No 69 0.272 0 0 0.0 1
FER1L5 FER1L5 A0AVI2 Fer-1-like protein 5 chr2 GO:0045321 Not Cancer Driver No 154 0.075 200 11 0.055 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0045321 Not Cancer Driver No 71 0.162 70 12 0.171 0
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0045321 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0045321 Census, Compendium Yes 109 0.161 448 71 0.158 3
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0045321 Not Cancer Driver No 96 0.274 26 5 0.192 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0045321 Not Cancer Driver No 28 0.082 25 3 0.12 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0045321 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0045321 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0045321 Not Cancer Driver No 90 0.157 22 2 0.091 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0045321 Not Cancer Driver No 72 0.104 146 3 0.021 0
GAPT GAPT Q8N292 Protein GAPT chr5 GO:0045321 Not Cancer Driver No 41 0.261 83 27 0.325 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0045321 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0045321 Not Cancer Driver No 74 0.138 38 5 0.132 171
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0045321 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0045321 Not Cancer Driver No 53 0.147 25 3 0.12 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0045321 Not Cancer Driver No 36 0.109 0 0 0.0 0
GRN GRN P28799 Progranulin chr17 GO:0045321 Not Cancer Driver No 76 0.128 29 6 0.207 1
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0045321 Not Cancer Driver No 69 0.229 17 2 0.118 3
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 GO:0045321 Not Cancer Driver No 274 0.105 991 108 0.109 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0045321 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0045321 Not Cancer Driver No 63 0.176 138 39 0.283 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0045321 Not Cancer Driver No 25 0.116 203 20 0.099 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0045321 Not Cancer Driver No 61 0.106 82 6 0.073 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0045321 Not Cancer Driver No 52 0.11 8 1 0.125 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0045321 Not Cancer Driver No 61 0.115 251 28 0.112 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:0045321 Not Cancer Driver No 33 0.115 63 10 0.159 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0045321 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0045321 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0045321 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0045321 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0045321 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0045321 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0045321 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0045321 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0045321 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0045321 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0045321 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0045321 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0045321 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0045321 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0045321 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0045321 Compendium Yes 55 0.112 175 22 0.126 10
IFNGR2_ENST00000290219 IFNGR2 P38484 Interferon gamma receptor 2 chr21 GO:0045321 Not Cancer Driver No 36 0.107 18 2 0.111 5
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0045321 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0045321 Not Cancer Driver No 32 0.164 10 3 0.3 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0045321 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0045321 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0045321 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0045321 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0045321 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0045321 Census Yes 24 0.157 6 1 0.167 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0045321 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL21R_ENST00000395754 IL21R Q9HBE5 Interleukin-21 receptor chr16 GO:0045321 Census Yes 133 0.247 183 47 0.257 1
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 GO:0045321 Not Cancer Driver No 81 0.147 182 33 0.181 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0045321 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0045321 Not Cancer Driver No 35 0.165 58 7 0.121 0
INS INS P01308 Insulin chr11 GO:0045321 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0045321 Compendium Yes 49 0.151 228 31 0.136 2
IRF2BP2 IRF2BP2 Q7Z5L9 Interferon regulatory factor 2-binding protein 2 chr1 GO:0045321 Not Cancer Driver No 42 0.072 451 26 0.058 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0045321 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0045321 Not Cancer Driver No 80 0.188 77 20 0.26 2
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0045321 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGAL ITGAL P20701 Integrin alpha-L chr16 GO:0045321 Not Cancer Driver No 196 0.168 144 25 0.174 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0045321 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0045321 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0045321 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 GO:0045321 Not Cancer Driver No 126 0.164 26 3 0.115 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0045321 Census Yes 139 0.224 43 10 0.233 1
ITM2A ITM2A O43736 Integral membrane protein 2A chrX GO:0045321 Not Cancer Driver No 75 0.285 26 9 0.346 0
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0045321 Not Cancer Driver No 126 0.102 158 24 0.152 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0045321 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAML JAML Q86YT9 Junctional adhesion molecule-like chr11 GO:0045321 Not Cancer Driver No 72 0.183 68 11 0.162 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0045321 Not Cancer Driver No 51 0.127 133 21 0.158 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0045321 Census Yes 35 0.106 281 25 0.089 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0045321 Not Cancer Driver No 88 0.147 160 15 0.094 12
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0045321 Census Yes 97 0.159 327 47 0.144 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0045321 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0045321 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRF2 KLRF2 D3W0D1 Killer cell lectin-like receptor subfamily F member 2 chr12 GO:0045321 Not Cancer Driver No 1 0.005 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0045321 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0045321 Not Cancer Driver No 233 0.125 1613 198 0.123 4
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0045321 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAT2 LAT2 Q9GZY6 Linker for activation of T-cells family member 2 chr7 GO:0045321 Not Cancer Driver No 39 0.16 176 29 0.165 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0045321 Not Cancer Driver No 37 0.141 213 29 0.136 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0045321 Not Cancer Driver No 84 0.175 6 0 0.0 0
LCP2 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 GO:0045321 Not Cancer Driver No 107 0.201 390 80 0.205 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0045321 Census Yes 64 0.16 370 57 0.154 0
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0045321 Not Cancer Driver No 37 0.098 65 1 0.015 1
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0045321 Not Cancer Driver No 16 0.119 0 0 0.0 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0045321 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0045321 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0045321 Not Cancer Driver No 203 0.312 291 97 0.333 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0045321 Not Cancer Driver No 105 0.13 32 3 0.094 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 GO:0045321 Not Cancer Driver No 44 0.101 200 21 0.105 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0045321 Census Yes 35 0.108 301 34 0.113 10
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0045321 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0045321 Not Cancer Driver No 128 0.169 750 126 0.168 18
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0045321 Not Cancer Driver No 175 0.175 159 31 0.195 3
MFNG MFNG O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe chr22 GO:0045321 Not Cancer Driver No 37 0.115 29 4 0.138 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0045321 Not Cancer Driver No 56 0.146 175 22 0.126 0
MILR1 MILR1 Q7Z6M3 Allergin-1 chr17 GO:0045321 Not Cancer Driver No 11 0.032 60 4 0.067 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0045321 Census Yes 92 0.122 208 22 0.106 85
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0045321 Not Cancer Driver No 60 0.176 33 7 0.212 0
MRGPRX2 MRGPRX2 Q96LB1 Mas-related G-protein coupled receptor member X2 chr11 GO:0045321 Not Cancer Driver No 86 0.261 11 2 0.182 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0045321 Census Yes 92 0.099 37 4 0.108 70
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0045321 Census Yes 154 0.113 386 41 0.106 6
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0045321 Not Cancer Driver No 9 0.145 0 0 0.0 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0045321 Census, Compendium Yes 37 0.125 47 1 0.021 2
NBN NBN O60934 Nibrin chr8 GO:0045321 Census Yes 90 0.119 417 54 0.129 1
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 GO:0045321 Not Cancer Driver No 67 0.111 335 39 0.116 0
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0045321 Not Cancer Driver No 81 0.266 27 8 0.296 0
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 GO:0045321 Not Cancer Driver No 26 0.129 31 2 0.065 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0045321 Census Yes 66 0.168 140 22 0.157 0
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 GO:0045321 Not Cancer Driver No 57 0.123 333 41 0.123 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0045321 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKG7 NKG7 Q16617 Protein NKG7 chr19 GO:0045321 Not Cancer Driver No 34 0.206 0 0 0.0 0
NKX2-3 NKX2-3 Q8TAU0 Homeobox protein Nkx-2.3 chr10 GO:0045321 Not Cancer Driver No 31 0.085 212 27 0.127 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0045321 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0045321 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0045321 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0045321 Census Yes 83 0.133 298 37 0.124 0
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0045321 Census Yes 82 0.191 290 57 0.197 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0045321 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0045321 Not Cancer Driver No 318 0.289 121 39 0.322 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0045321 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0045321 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0045321 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0045321 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0045321 Not Cancer Driver No 185 0.164 274 31 0.113 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 GO:0045321 Census Yes 59 0.23 181 45 0.249 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0045321 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0045321 Not Cancer Driver No 24 0.121 30 4 0.133 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0045321 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRG3 PRG3 Q9Y2Y8 Proteoglycan 3 chr11 GO:0045321 Not Cancer Driver No 40 0.178 60 12 0.2 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0045321 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0045321 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0045321 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0045321 Not Cancer Driver No 10 0.036 199 6 0.03 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0045321 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMB11 PSMB11 A5LHX3 Proteasome subunit beta type-11 chr14 GO:0045321 Not Cancer Driver No 62 0.207 71 11 0.155 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0045321 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGDS PTGDS P41222 Prostaglandin-H2 D-isomerase chr9 GO:0045321 Not Cancer Driver No 31 0.163 13 3 0.231 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0045321 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0045321 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0045321 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0045321 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0045321 Not Cancer Driver No 25 0.113 15 4 0.267 3
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 GO:0045321 Not Cancer Driver No 37 0.157 1 0 0.0 1
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0045321 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0045321 Not Cancer Driver No 118 0.224 85 23 0.271 6
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0045321 Not Cancer Driver No 96 0.12 191 12 0.063 1
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0045321 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0045321 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0045321 Not Cancer Driver No 128 0.107 703 81 0.115 0
RELB RELB Q01201 Transcription factor RelB chr19 GO:0045321 Not Cancer Driver No 65 0.112 348 39 0.112 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0045321 Census Yes 41 0.215 12 3 0.25 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0045321 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0045321 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0045321 Not Cancer Driver No 56 0.115 226 29 0.128 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0045321 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0045321 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0045321 Not Cancer Driver No 38 0.153 150 25 0.167 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0045321 Not Cancer Driver No 68 0.188 22 1 0.045 0
S100A12 S100A12 P80511 Protein S100-A12 chr1 GO:0045321 Not Cancer Driver No 18 0.196 1 0 0.0 0
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0045321 Not Cancer Driver No 12 0.122 6 0 0.0 0
SBNO2 SBNO2 Q9Y2G9 Protein strawberry notch homolog 2 chr19 GO:0045321 Not Cancer Driver No 108 0.079 456 29 0.064 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0045321 Not Cancer Driver No 90 0.141 62 4 0.065 13
SELPLG_ENST00000550948 SELPLG Q14242 P-selectin glycoprotein ligand 1 chr12 GO:0045321 Not Cancer Driver No 68 0.165 297 48 0.162 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0045321 Not Cancer Driver No 123 0.162 122 26 0.213 4
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0045321 Not Cancer Driver No 56 0.121 139 14 0.101 81
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0045321 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 GO:0045321 Not Cancer Driver No 66 0.197 53 14 0.264 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0045321 Not Cancer Driver No 79 0.144 47 5 0.106 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0045321 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0045321 Not Cancer Driver No 85 0.137 564 77 0.137 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0045321 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPACA3 SPACA3 Q8IXA5 Sperm acrosome membrane-associated protein 3 chr17 GO:0045321 Not Cancer Driver No 52 0.242 0 0 0.0 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0045321 Not Cancer Driver No 46 0.17 187 34 0.182 0
ST3GAL1_ENST00000522652 ST3GAL1 Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 chr8 GO:0045321 Not Cancer Driver No 51 0.15 6 0 0.0 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0045321 Census, Compendium Yes 93 0.118 144 19 0.132 5
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0045321 Not Cancer Driver No 40 0.112 117 9 0.077 0
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0045321 Not Cancer Driver No 77 0.13 80 13 0.163 5
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0045321 Not Cancer Driver No 59 0.1 64 9 0.141 0
SUCNR1 SUCNR1 Q9BXA5 Succinate receptor 1 chr3 GO:0045321 Not Cancer Driver No 51 0.153 0 0 0.0 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0045321 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0045321 Census Yes 96 0.151 131 27 0.206 5
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0045321 Not Cancer Driver No 63 0.102 284 32 0.113 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0045321 Not Cancer Driver No 101 0.139 42 5 0.119 12
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0045321 Compendium Yes 68 0.082 102 6 0.059 5
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0045321 Not Cancer Driver No 127 0.244 284 84 0.296 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0045321 Census, Compendium Yes 106 0.187 60 16 0.267 25
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0045321 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0045321 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0045321 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0045321 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0045321 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0045321 Not Cancer Driver No 99 0.124 1 0 0.0 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0045321 Not Cancer Driver No 26 0.099 9 1 0.111 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0045321 Not Cancer Driver No 39 0.173 27 3 0.111 2
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045321 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0045321 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF8 TNFSF8 P32971 Tumor necrosis factor ligand superfamily member 8 chr9 GO:0045321 Not Cancer Driver No 34 0.145 30 2 0.067 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0045321 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0045321 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0045321 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0045321 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0045321 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0045321 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0045321 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0045321 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0045321 Census, Compendium Yes 135 0.116 732 78 0.107 11
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0045321 Not Cancer Driver No 10 0.091 31 3 0.097 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0045321 Not Cancer Driver No 119 0.134 197 17 0.086 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0045321 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBD UBD O15205 Ubiquitin D chr6 GO:0045321 Not Cancer Driver No 31 0.188 8 1 0.125 0
ULBP1 ULBP1 Q9BZM6 UL16-binding protein 1 chr6 GO:0045321 Not Cancer Driver No 48 0.197 24 4 0.167 0
ULBP2 ULBP2 Q9BZM5 UL16-binding protein 2 chr6 GO:0045321 Not Cancer Driver No 33 0.134 25 2 0.08 0
ULBP3 ULBP3 Q9BZM4 UL16-binding protein 3 chr6 GO:0045321 Not Cancer Driver No 34 0.139 14 1 0.071 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0045321 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0045321 Not Cancer Driver No 34 0.109 96 13 0.135 1
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0045321 Not Cancer Driver No 7 0.06 47 4 0.085 3
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0045321 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0045321 Not Cancer Driver No 9 0.09 27 0 0.0 0
WDFY4 WDFY4 Q6ZS81 WD repeat- and FYVE domain-containing protein 4 chr10 GO:0045321 Not Cancer Driver No 217 0.068 475 36 0.076 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0045321 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0045321 Not Cancer Driver No 30 0.085 39 4 0.103 4
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0045321 Compendium Yes 103 0.191 353 70 0.198 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0045321 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0045321 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF3 ZNF3 P17036 Zinc finger protein 3 chr7 GO:0045321 Not Cancer Driver No 54 0.121 199 26 0.131 0