Total number of protein in "GO:2001238" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:2001238 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AGTR2 | AGTR2 | P50052 | Type-2 angiotensin II receptor | chrX | GO:2001238 | Not Cancer Driver | No | 98 | 0.27 | 0 | 0 | 0.0 | 0 |
| ATF3_ENST00000366987 | ATF3 | P18847 | Cyclic AMP-dependent transcription factor ATF-3 | chr1 | GO:2001238 | Not Cancer Driver | No | 23 | 0.127 | 118 | 14 | 0.119 | 0 |
| BCL10 | BCL10 | O95999 | B-cell lymphoma/leukemia 10 | chr1 | GO:2001238 | Census, Compendium | Yes | 36 | 0.155 | 151 | 25 | 0.166 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:2001238 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BMPR1B_ENST00000394931 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:2001238 | Not Cancer Driver | No | 84 | 0.167 | 64 | 12 | 0.188 | 5 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:2001238 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CTNNA1 | CTNNA1 | P35221 | Catenin alpha-1 | chr5 | GO:2001238 | Census | Yes | 126 | 0.139 | 268 | 35 | 0.131 | 4 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:2001238 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| DEDD2 | DEDD2 | Q8WXF8 | DNA-binding death effector domain-containing protein 2 | chr19 | GO:2001238 | Not Cancer Driver | No | 42 | 0.129 | 133 | 25 | 0.188 | 0 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:2001238 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:2001238 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| G0S2 | G0S2 | P27469 | G0/G1 switch protein 2 | chr1 | GO:2001238 | Not Cancer Driver | No | 8 | 0.078 | 28 | 5 | 0.179 | 0 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:2001238 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:2001238 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:2001238 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| INHBA_ENST00000442711 | INHBA | P08476 | Inhibin beta A chain | chr7 | GO:2001238 | Not Cancer Driver | No | 148 | 0.347 | 154 | 63 | 0.409 | 0 |
| ITM2C | ITM2C | Q9NQX7 | Integral membrane protein 2C | chr2 | GO:2001238 | Not Cancer Driver | No | 31 | 0.116 | 33 | 4 | 0.121 | 0 |
| LTBR | LTBR | P36941 | Tumor necrosis factor receptor superfamily member 3 | chr12 | GO:2001238 | Not Cancer Driver | No | 44 | 0.101 | 200 | 21 | 0.105 | 0 |
| MAL | MAL | P21145 | Myelin and lymphocyte protein | chr2 | GO:2001238 | Not Cancer Driver | No | 21 | 0.137 | 0 | 0 | 0.0 | 0 |
| NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:2001238 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:2001238 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PDIA3 | PDIA3 | P30101 | Protein disulfide-isomerase A3 | chr15 | GO:2001238 | Not Cancer Driver | No | 57 | 0.113 | 98 | 11 | 0.112 | 0 |
| PEA15_ENST00000360472 | PEA15 | Q15121 | Astrocytic phosphoprotein PEA-15 | chr1 | GO:2001238 | Not Cancer Driver | No | 12 | 0.092 | 35 | 5 | 0.143 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | GO:2001238 | Not Cancer Driver | No | 2 | 0.037 | 23 | 1 | 0.043 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:2001238 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | GO:2001238 | Not Cancer Driver | No | 38 | 0.115 | 27 | 6 | 0.222 | 0 |
| PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | GO:2001238 | Census, Compendium | Yes | 179 | 0.304 | 0 | 0 | 0.0 | 4 |
| PPP2R1B_ENST00000527614 | PPP2R1B | P30154 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | chr11 | GO:2001238 | Not Cancer Driver | No | 72 | 0.12 | 17 | 1 | 0.059 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:2001238 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:2001238 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:2001238 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | GO:2001238 | Not Cancer Driver | No | 52 | 0.102 | 140 | 14 | 0.1 | 2 |
| RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:2001238 | Census, Compendium | Yes | 208 | 0.187 | 105 | 12 | 0.114 | 139 |
| RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:2001238 | Compendium | Yes | 82 | 0.122 | 277 | 39 | 0.141 | 4 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:2001238 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | GO:2001238 | Not Cancer Driver | No | 77 | 0.113 | 356 | 32 | 0.09 | 0 |
| SRPX | SRPX | P78539 | Sushi repeat-containing protein SRPX | chrX | GO:2001238 | Not Cancer Driver | No | 71 | 0.153 | 60 | 10 | 0.167 | 0 |
| STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:2001238 | Not Cancer Driver | No | 70 | 0.143 | 241 | 32 | 0.133 | 0 |
| STK4 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:2001238 | Not Cancer Driver | No | 70 | 0.144 | 231 | 30 | 0.13 | 0 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:2001238 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| TIMP3 | TIMP3 | P35625 | Metalloproteinase inhibitor 3 | chr22 | GO:2001238 | Not Cancer Driver | No | 43 | 0.204 | 3 | 1 | 0.333 | 5 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:2001238 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF12A | TNFRSF12A | Q9NP84 | Tumor necrosis factor receptor superfamily member 12A | chr16 | GO:2001238 | Not Cancer Driver | No | 8 | 0.062 | 0 | 0 | 0.0 | 0 |
| TNFSF10 | TNFSF10 | P50591 | Tumor necrosis factor ligand superfamily member 10 | chr3 | GO:2001238 | Not Cancer Driver | No | 43 | 0.153 | 61 | 7 | 0.115 | 0 |
| TNFSF12 | TNFSF12 | O43508 | Tumor necrosis factor ligand superfamily member 12 | chr17 | GO:2001238 | Not Cancer Driver | No | 28 | 0.112 | 109 | 8 | 0.073 | 0 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:2001238 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | GO:2001238 | Not Cancer Driver | No | 79 | 0.191 | 108 | 9 | 0.083 | 3 |
| ZSWIM2 | ZSWIM2 | Q8NEG5 | E3 ubiquitin-protein ligase ZSWIM2 | chr2 | GO:2001238 | Not Cancer Driver | No | 189 | 0.299 | 85 | 30 | 0.353 | 0 |