Total number of protein in "GO:0070374" GO term: 202
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA7 | ABCA7 | Q8IZY2 | Phospholipid-transporting ATPase ABCA7 | chr19 | GO:0070374 | Not Cancer Driver | No | 260 | 0.121 | 402 | 35 | 0.087 | 1 |
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0070374 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ACKR3 | ACKR3 | P25106 | Atypical chemokine receptor 3 | chr2 | GO:0070374 | Census, Compendium | Yes | 78 | 0.215 | 0 | 0 | 0.0 | 1 |
| ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | GO:0070374 | Not Cancer Driver | No | 50 | 0.133 | 39 | 4 | 0.103 | 17 |
| ADCYAP1_ENST00000450565 | ADCYAP1 | P18509 | Pituitary adenylate cyclase-activating polypeptide | chr18 | GO:0070374 | Not Cancer Driver | No | 43 | 0.244 | 75 | 11 | 0.147 | 0 |
| ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0070374 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0070374 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AKAP12 | AKAP12 | Q02952 | A-kinase anchor protein 12 | chr6 | GO:0070374 | Not Cancer Driver | No | 215 | 0.121 | 1770 | 214 | 0.121 | 0 |
| ALKAL1 | ALKAL1 | Q6UXT8 | ALK and LTK ligand 1 | chr8 | GO:0070374 | Not Cancer Driver | No | 18 | 0.14 | 49 | 3 | 0.061 | 0 |
| ALKAL2 | ALKAL2 | Q6UX46 | ALK and LTK ligand 2 | chr2 | GO:0070374 | Not Cancer Driver | No | 7 | 0.046 | 31 | 0 | 0.0 | 0 |
| ALOX15_ENST00000293761 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0070374 | Not Cancer Driver | No | 84 | 0.127 | 46 | 7 | 0.152 | 0 |
| ANGPT1 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0070374 | Not Cancer Driver | No | 130 | 0.261 | 131 | 24 | 0.183 | 1 |
| APELA | APELA | P0DMC3 | Apelin receptor early endogenous ligand | chr4 | GO:0070374 | Not Cancer Driver | No | 1 | 0.019 | 0 | 0 | 0.0 | 0 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0070374 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0070374 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| ARHGAP8 | ARHGAP8 | P85298 | Rho GTPase-activating protein 8 | chr22 | GO:0070374 | Not Cancer Driver | No | 65 | 0.14 | 75 | 13 | 0.173 | 0 |
| ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | GO:0070374 | Not Cancer Driver | No | 49 | 0.117 | 154 | 13 | 0.084 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0070374 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0070374 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0070374 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMPER | BMPER | Q8N8U9 | BMP-binding endothelial regulator protein | chr7 | GO:0070374 | Not Cancer Driver | No | 196 | 0.286 | 0 | 0 | 0.0 | 1 |
| BRAF | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | GO:0070374 | Census, Compendium | Yes | 791 | 1.033 | 310 | 43 | 0.139 | 39 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0070374 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| C5AR2_ENST00000600626 | C5AR2 | Q9P296 | C5a anaphylatoxin chemotactic receptor 2 | chr19 | GO:0070374 | Not Cancer Driver | No | 60 | 0.178 | 11 | 3 | 0.273 | 0 |
| CALCR_ENST00000394441 | CALCR | P30988 | Calcitonin receptor | chr7 | GO:0070374 | Not Cancer Driver | No | 162 | 0.342 | 29 | 9 | 0.31 | 0 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0070374 | Not Cancer Driver | No | 72 | 0.134 | 225 | 35 | 0.156 | 11 |
| CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0070374 | Not Cancer Driver | No | 304 | 0.282 | 189 | 60 | 0.317 | 108 |
| CAVIN3 | CAVIN3 | Q969G5 | Caveolae-associated protein 3 | chr11 | GO:0070374 | Not Cancer Driver | No | 22 | 0.084 | 234 | 19 | 0.081 | 0 |
| CCL1 | CCL1 | P22362 | C-C motif chemokine 1 | chr17 | GO:0070374 | Not Cancer Driver | No | 27 | 0.281 | 0 | 0 | 0.0 | 0 |
| CCL11 | CCL11 | P51671 | Eotaxin | chr17 | GO:0070374 | Not Cancer Driver | No | 18 | 0.186 | 14 | 3 | 0.214 | 0 |
| CCL13 | CCL13 | Q99616 | C-C motif chemokine 13 | chr17 | GO:0070374 | Not Cancer Driver | No | 15 | 0.153 | 1 | 0 | 0.0 | 0 |
| CCL17_ENST00000616880 | CCL17 | Q92583 | C-C motif chemokine 17 | chr16 | GO:0070374 | Not Cancer Driver | No | 10 | 0.106 | 0 | 0 | 0.0 | 0 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0070374 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CCL2 | CCL2 | P13500 | C-C motif chemokine 2 | chr17 | GO:0070374 | Not Cancer Driver | No | 20 | 0.202 | 15 | 5 | 0.333 | 0 |
| CCL20 | CCL20 | P78556 | C-C motif chemokine 20 | chr2 | GO:0070374 | Not Cancer Driver | No | 16 | 0.167 | 0 | 0 | 0.0 | 0 |
| CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0070374 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
| CCL22 | CCL22 | O00626 | C-C motif chemokine 22 | chr16 | GO:0070374 | Not Cancer Driver | No | 19 | 0.204 | 0 | 0 | 0.0 | 0 |
| CCL24_ENST00000222902 | CCL24 | O00175 | C-C motif chemokine 24 | chr7 | GO:0070374 | Not Cancer Driver | No | 25 | 0.21 | 23 | 3 | 0.13 | 0 |
| CCL25 | CCL25 | O15444 | C-C motif chemokine 25 | chr19 | GO:0070374 | Not Cancer Driver | No | 20 | 0.133 | 26 | 6 | 0.231 | 0 |
| CCL26_ENST00000005180 | CCL26 | Q9Y258 | C-C motif chemokine 26 | chr7 | GO:0070374 | Not Cancer Driver | No | 9 | 0.096 | 0 | 0 | 0.0 | 0 |
| CCL7 | CCL7 | P80098 | C-C motif chemokine 7 | chr17 | GO:0070374 | Not Cancer Driver | No | 30 | 0.303 | 13 | 3 | 0.231 | 0 |
| CCL8 | CCL8 | P80075 | C-C motif chemokine 8 | chr17 | GO:0070374 | Not Cancer Driver | No | 17 | 0.172 | 0 | 0 | 0.0 | 0 |
| CCN2 | CCN2 | P29279 | CCN family member 2 | chr6 | GO:0070374 | Not Cancer Driver | No | 58 | 0.166 | 0 | 0 | 0.0 | 0 |
| CCR1 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | GO:0070374 | Not Cancer Driver | No | 69 | 0.194 | 14 | 5 | 0.357 | 0 |
| CCR7 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0070374 | Census, Compendium | Yes | 50 | 0.132 | 0 | 0 | 0.0 | 0 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0070374 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CD4 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:0070374 | Not Cancer Driver | No | 69 | 0.151 | 56 | 11 | 0.196 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:0070374 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
| CD74 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0070374 | Census | Yes | 31 | 0.105 | 185 | 20 | 0.108 | 0 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0070374 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| CHI3L1 | CHI3L1 | P36222 | Chitinase-3-like protein 1 | chr1 | GO:0070374 | Not Cancer Driver | No | 66 | 0.172 | 24 | 5 | 0.208 | 0 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0070374 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0070374 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0070374 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| CSF1R | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0070374 | Census | Yes | 133 | 0.137 | 124 | 17 | 0.137 | 20 |
| CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0070374 | Not Cancer Driver | No | 66 | 0.166 | 259 | 44 | 0.17 | 0 |
| CXCL17 | CXCL17 | Q6UXB2 | C-X-C motif chemokine 17 | chr19 | GO:0070374 | Not Cancer Driver | No | 8 | 0.067 | 44 | 6 | 0.136 | 0 |
| DDT_ENST00000350608 | DDT | P30046 | D-dopachrome decarboxylase | chr22 | GO:0070374 | Not Cancer Driver | No | 4 | 0.034 | 0 | 0 | 0.0 | 0 |
| DNAJC27 | DNAJC27 | Q9NZQ0 | DnaJ homolog subfamily C member 27 | chr2 | GO:0070374 | Not Cancer Driver | No | 33 | 0.121 | 36 | 4 | 0.111 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0070374 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DSTYK | DSTYK | Q6XUX3 | Dual serine/threonine and tyrosine protein kinase | chr1 | GO:0070374 | Not Cancer Driver | No | 112 | 0.121 | 112 | 4 | 0.036 | 2 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0070374 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0070374 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0070374 | Census, Compendium | Yes | 428 | 0.327 | 323 | 116 | 0.359 | 2 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0070374 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0070374 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0070374 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0070374 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FFAR4_ENST00000371481 | FFAR4 | Q5NUL3 | Free fatty acid receptor 4 | chr10 | GO:0070374 | Not Cancer Driver | No | 47 | 0.13 | 0 | 0 | 0.0 | 0 |
| FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | GO:0070374 | Not Cancer Driver | No | 245 | 0.283 | 522 | 149 | 0.285 | 7 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0070374 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0070374 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FGF18 | FGF18 | O76093 | Fibroblast growth factor 18 | chr5 | GO:0070374 | Not Cancer Driver | No | 40 | 0.193 | 57 | 14 | 0.246 | 0 |
| FGF19 | FGF19 | O95750 | Fibroblast growth factor 19 | chr11 | GO:0070374 | Not Cancer Driver | No | 20 | 0.093 | 36 | 7 | 0.194 | 0 |
| FGF1_ENST00000612258 | FGF1 | P05230 | Fibroblast growth factor 1 | chr5 | GO:0070374 | Not Cancer Driver | No | 30 | 0.194 | 29 | 2 | 0.069 | 0 |
| FGF20 | FGF20 | Q9NP95 | Fibroblast growth factor 20 | chr8 | GO:0070374 | Not Cancer Driver | No | 25 | 0.118 | 57 | 3 | 0.053 | 0 |
| FGF21 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0070374 | Not Cancer Driver | No | 37 | 0.177 | 109 | 24 | 0.22 | 0 |
| FGF23 | FGF23 | Q9GZV9 | Fibroblast growth factor 23 | chr12 | GO:0070374 | Not Cancer Driver | No | 84 | 0.335 | 97 | 51 | 0.526 | 7 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0070374 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FGF4 | FGF4 | P08620 | Fibroblast growth factor 4 | chr11 | GO:0070374 | Not Cancer Driver | No | 16 | 0.078 | 21 | 3 | 0.143 | 0 |
| FGF8_ENST00000344255 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | GO:0070374 | Not Cancer Driver | No | 30 | 0.129 | 79 | 9 | 0.114 | 6 |
| FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0070374 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
| FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0070374 | Census, Compendium | Yes | 173 | 0.215 | 241 | 26 | 0.108 | 37 |
| FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0070374 | Census, Compendium | Yes | 113 | 0.141 | 162 | 28 | 0.173 | 0 |
| FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0070374 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
| FLT4 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0070374 | Census, Compendium | Yes | 253 | 0.186 | 259 | 41 | 0.158 | 13 |
| FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0070374 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
| FSHR | FSHR | P23945 | Follicle-stimulating hormone receptor | chr2 | GO:0070374 | Not Cancer Driver | No | 226 | 0.325 | 28 | 11 | 0.393 | 16 |
| GAREM1 | GAREM1 | Q9H706 | GRB2-associated and regulator of MAPK protein 1 | chr18 | GO:0070374 | Not Cancer Driver | No | 128 | 0.146 | 408 | 50 | 0.123 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0070374 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0070374 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
| GCG | GCG | P01275 | Pro-glucagon | chr2 | GO:0070374 | Not Cancer Driver | No | 49 | 0.272 | 82 | 22 | 0.268 | 0 |
| GCNT2_ENST00000379597 | GCNT2 | Q8N0V5 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase | chr6 | GO:0070374 | Not Cancer Driver | No | 40 | 0.1 | 3 | 0 | 0.0 | 0 |
| GLIPR2 | GLIPR2 | Q9H4G4 | Golgi-associated plant pathogenesis-related protein 1 | chr9 | GO:0070374 | Not Cancer Driver | No | 16 | 0.104 | 77 | 10 | 0.13 | 0 |
| GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | GO:0070374 | Compendium | Yes | 50 | 0.141 | 24 | 0 | 0.0 | 0 |
| GPBAR1_ENST00000521462 | GPBAR1 | Q8TDU6 | G-protein coupled bile acid receptor 1 | chr2 | GO:0070374 | Not Cancer Driver | No | 30 | 0.091 | 22 | 4 | 0.182 | 0 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0070374 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GPNMB | GPNMB | Q14956 | Transmembrane glycoprotein NMB | chr7 | GO:0070374 | Not Cancer Driver | No | 89 | 0.156 | 94 | 18 | 0.191 | 0 |
| GPR183 | GPR183 | P32249 | G-protein coupled receptor 183 | chr13 | GO:0070374 | Not Cancer Driver | No | 53 | 0.147 | 25 | 3 | 0.12 | 0 |
| GPR55 | GPR55 | Q9Y2T6 | G-protein coupled receptor 55 | chr2 | GO:0070374 | Not Cancer Driver | No | 64 | 0.201 | 0 | 0 | 0.0 | 0 |
| HAND2 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0070374 | Not Cancer Driver | No | 47 | 0.217 | 124 | 29 | 0.234 | 0 |
| HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:0070374 | Not Cancer Driver | No | 69 | 0.229 | 17 | 2 | 0.118 | 3 |
| HCRTR1 | HCRTR1 | O43613 | Orexin/Hypocretin receptor type 1 | chr1 | GO:0070374 | Not Cancer Driver | No | 52 | 0.122 | 28 | 0 | 0.0 | 0 |
| HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | GO:0070374 | Not Cancer Driver | No | 48 | 0.18 | 12 | 1 | 0.083 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0070374 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | GO:0070374 | Census, Compendium | Yes | 107 | 0.566 | 16 | 4 | 0.25 | 18 |
| HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0070374 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
| HTR2B | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0070374 | Not Cancer Driver | No | 41 | 0.085 | 23 | 2 | 0.087 | 0 |
| HTR2C | HTR2C | P28335 | 5-hydroxytryptamine receptor 2C | chrX | GO:0070374 | Not Cancer Driver | No | 140 | 0.306 | 40 | 11 | 0.275 | 0 |
| ICAM1 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | GO:0070374 | Not Cancer Driver | No | 61 | 0.115 | 251 | 28 | 0.112 | 0 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0070374 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0070374 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| IL26 | IL26 | Q9NPH9 | Interleukin-26 | chr12 | GO:0070374 | Not Cancer Driver | No | 38 | 0.222 | 0 | 0 | 0.0 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | GO:0070374 | Census | Yes | 35 | 0.106 | 281 | 25 | 0.089 | 0 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0070374 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0070374 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| MAP2K1 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | GO:0070374 | Census, Compendium | Yes | 94 | 0.239 | 96 | 24 | 0.25 | 6 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0070374 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
| MAP3K12_ENST00000267079 | MAP3K12 | Q12852 | Mitogen-activated protein kinase kinase kinase 12 | chr12 | GO:0070374 | Not Cancer Driver | No | 120 | 0.14 | 481 | 64 | 0.133 | 0 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0070374 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MARCO | MARCO | Q9UEW3 | Macrophage receptor MARCO | chr2 | GO:0070374 | Not Cancer Driver | No | 180 | 0.346 | 323 | 125 | 0.387 | 0 |
| MFHAS1 | MFHAS1 | Q9Y4C4 | Malignant fibrous histiocytoma-amplified sequence 1 | chr8 | GO:0070374 | Not Cancer Driver | No | 95 | 0.09 | 98 | 9 | 0.092 | 0 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0070374 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0070374 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| MTURN | MTURN | Q8N3F0 | Maturin | chr7 | GO:0070374 | Not Cancer Driver | No | 15 | 0.115 | 27 | 6 | 0.222 | 0 |
| NDRG4_ENST00000570248 | NDRG4 | Q9ULP0 | Protein NDRG4 | chr16 | GO:0070374 | Not Cancer Driver | No | 44 | 0.125 | 90 | 11 | 0.122 | 0 |
| NECAB2 | NECAB2 | Q7Z6G3 | N-terminal EF-hand calcium-binding protein 2 | chr16 | GO:0070374 | Not Cancer Driver | No | 46 | 0.119 | 122 | 9 | 0.074 | 0 |
| NELFE | NELFE | P18615 | Negative elongation factor E | chr6 | GO:0070374 | Not Cancer Driver | No | 47 | 0.124 | 352 | 45 | 0.128 | 0 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0070374 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0070374 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NODAL | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0070374 | Not Cancer Driver | No | 40 | 0.115 | 34 | 8 | 0.235 | 4 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0070374 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0070374 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| NOX4 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:0070374 | Not Cancer Driver | No | 123 | 0.213 | 0 | 0 | 0.0 | 0 |
| NPNT_ENST00000379987 | NPNT | Q6UXI9 | Nephronectin | chr4 | GO:0070374 | Not Cancer Driver | No | 90 | 0.159 | 218 | 33 | 0.151 | 0 |
| NPSR1_ENST00000360581 | NPSR1 | Q6W5P4 | Neuropeptide S receptor | chr7 | GO:0070374 | Not Cancer Driver | No | 111 | 0.299 | 9 | 7 | 0.778 | 0 |
| NPTN | NPTN | Q9Y639 | Neuroplastin | chr15 | GO:0070374 | Not Cancer Driver | No | 47 | 0.118 | 118 | 9 | 0.076 | 0 |
| NPY5R_ENST00000506953 | NPY5R | Q15761 | Neuropeptide Y receptor type 5 | chr4 | GO:0070374 | Not Cancer Driver | No | 144 | 0.324 | 44 | 16 | 0.364 | 0 |
| NPY_ENST00000405982 | NPY | P01303 | Pro-neuropeptide Y | chr7 | GO:0070374 | Not Cancer Driver | No | 29 | 0.299 | 43 | 19 | 0.442 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0070374 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0070374 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0070374 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| NTRK2_ENST00000323115 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0070374 | Not Cancer Driver | No | 155 | 0.189 | 117 | 18 | 0.154 | 1 |
| NTRK3_ENST00000629765 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0070374 | Census, Compendium | Yes | 249 | 0.297 | 57 | 21 | 0.368 | 0 |
| OPRM1_ENST00000330432 | OPRM1 | P35372 | Mu-type opioid receptor | chr6 | GO:0070374 | Not Cancer Driver | No | 107 | 0.268 | 58 | 27 | 0.466 | 0 |
| OR2AT4_ENST00000641593 | OR2AT4 | A6NND4 | Olfactory receptor 2AT4 | chr11 | GO:0070374 | Not Cancer Driver | No | 62 | 0.194 | 0 | 0 | 0.0 | 0 |
| P2RY1 | P2RY1 | P47900 | P2Y purinoceptor 1 | chr3 | GO:0070374 | Not Cancer Driver | No | 60 | 0.161 | 16 | 1 | 0.062 | 0 |
| P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | GO:0070374 | Not Cancer Driver | No | 50 | 0.152 | 10 | 5 | 0.5 | 0 |
| PDE8A_ENST00000394553 | PDE8A | O60658 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | chr15 | GO:0070374 | Not Cancer Driver | No | 78 | 0.094 | 187 | 17 | 0.091 | 0 |
| PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0070374 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
| PDGFB | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0070374 | Census | Yes | 37 | 0.154 | 99 | 22 | 0.222 | 2 |
| PDGFC | PDGFC | Q9NRA1 | Platelet-derived growth factor C | chr4 | GO:0070374 | Not Cancer Driver | No | 86 | 0.249 | 53 | 12 | 0.226 | 0 |
| PDGFD | PDGFD | Q9GZP0 | Platelet-derived growth factor D | chr11 | GO:0070374 | Not Cancer Driver | No | 85 | 0.23 | 37 | 13 | 0.351 | 0 |
| PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0070374 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0070374 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:0070374 | Not Cancer Driver | No | 31 | 0.104 | 26 | 4 | 0.154 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0070374 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PLA2G2A_ENST00000375111 | PLA2G2A | P14555 | Phospholipase A2, membrane associated | chr1 | GO:0070374 | Not Cancer Driver | No | 25 | 0.174 | 0 | 0 | 0.0 | 0 |
| PLA2G5 | PLA2G5 | P39877 | Phospholipase A2 group V | chr1 | GO:0070374 | Not Cancer Driver | No | 24 | 0.174 | 0 | 0 | 0.0 | 2 |
| PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0070374 | Not Cancer Driver | No | 94 | 0.14 | 154 | 22 | 0.143 | 0 |
| PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | GO:0070374 | Not Cancer Driver | No | 70 | 0.118 | 116 | 11 | 0.095 | 0 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0070374 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
| PRXL2C | PRXL2C | Q7RTV5 | Peroxiredoxin-like 2C | chr9 | GO:0070374 | Not Cancer Driver | No | 10 | 0.044 | 26 | 0 | 0.0 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0070374 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0070374 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0070374 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0070374 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0070374 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0070374 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RAMP3 | RAMP3 | O60896 | Receptor activity-modifying protein 3 | chr7 | GO:0070374 | Not Cancer Driver | No | 30 | 0.203 | 0 | 0 | 0.0 | 0 |
| RAP1A_ENST00000356415 | RAP1A | P62834 | Ras-related protein Rap-1A | chr1 | GO:0070374 | Not Cancer Driver | No | 27 | 0.147 | 5 | 0 | 0.0 | 0 |
| RAP1B_ENST00000393436 | RAP1B | P61224 | Ras-related protein Rap-1b | chr12 | GO:0070374 | Not Cancer Driver | No | 26 | 0.141 | 14 | 3 | 0.214 | 0 |
| RAPGEF2 | RAPGEF2 | Q9Y4G8 | Rap guanine nucleotide exchange factor 2 | chr4 | GO:0070374 | Not Cancer Driver | No | 216 | 0.144 | 803 | 116 | 0.144 | 0 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0070374 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0070374 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| ROR1 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | GO:0070374 | Not Cancer Driver | No | 144 | 0.154 | 280 | 43 | 0.154 | 1 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0070374 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| S100A7_ENST00000368722 | S100A7 | P31151 | Protein S100-A7 | chr1 | GO:0070374 | Census | Yes | 39 | 0.386 | 28 | 14 | 0.5 | 0 |
| SCIMP | SCIMP | Q6UWF3 | SLP adapter and CSK-interacting membrane protein | chr17 | GO:0070374 | Not Cancer Driver | No | 10 | 0.069 | 73 | 9 | 0.123 | 0 |
| SEMA7A | SEMA7A | O75326 | Semaphorin-7A | chr15 | GO:0070374 | Not Cancer Driver | No | 81 | 0.122 | 150 | 21 | 0.14 | 0 |
| SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0070374 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0070374 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
| SLAMF1_ENST00000302035 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0070374 | Not Cancer Driver | No | 82 | 0.245 | 64 | 10 | 0.156 | 0 |
| SLC30A10 | SLC30A10 | Q6XR72 | Zinc transporter 10 | chr1 | GO:0070374 | Not Cancer Driver | No | 68 | 0.14 | 61 | 10 | 0.164 | 2 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0070374 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0070374 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SSTR4 | SSTR4 | P31391 | Somatostatin receptor type 4 | chr20 | GO:0070374 | Not Cancer Driver | No | 129 | 0.332 | 39 | 12 | 0.308 | 0 |
| ST5 | DENND2B | P78524 | DENN domain-containing protein 2B | chr11 | GO:0070374 | Not Cancer Driver | No | 144 | 0.127 | 671 | 93 | 0.139 | 0 |
| TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0070374 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0070374 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| THPO | THPO | P40225 | Thrombopoietin | chr3 | GO:0070374 | Not Cancer Driver | No | 63 | 0.178 | 163 | 25 | 0.153 | 0 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0070374 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0070374 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0070374 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFAIP8L3 | TNFAIP8L3 | Q5GJ75 | Tumor necrosis factor alpha-induced protein 8-like protein 3 | chr15 | GO:0070374 | Not Cancer Driver | No | 40 | 0.137 | 111 | 12 | 0.108 | 0 |
| TNFRSF11A | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0070374 | Not Cancer Driver | No | 70 | 0.114 | 285 | 33 | 0.116 | 0 |
| TNFSF11 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0070374 | Not Cancer Driver | No | 52 | 0.164 | 56 | 1 | 0.018 | 1 |
| TPBG_ENST00000543496 | TPBG | Q13641 | Trophoblast glycoprotein | chr6 | GO:0070374 | Not Cancer Driver | No | 58 | 0.138 | 13 | 1 | 0.077 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0070374 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0070374 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0070374 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
| XCL2 | XCL2 | Q9UBD3 | Cytokine SCM-1 beta | chr1 | GO:0070374 | Not Cancer Driver | No | 20 | 0.175 | 35 | 5 | 0.143 | 0 |