| GO term | GO name | GO namespace | GO def |
| GO:0036211 | protein modification process | biological_process | The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). [GOC:bf, GOC:jl] |
| GO:0009058 | biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [GOC:curators, ISBN:0198547684] |
| GO:0072522 | purine-containing compound biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. [GOC:mah] |
| GO:0006164 | purine nucleotide biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732] |
| GO:1901215 | negative regulation of neuron death | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of neuron death. [GOC:rph, GOC:TermGenie] |
| GO:0007269 | neurotransmitter secretion | biological_process | The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. [GOC:dph] |
| GO:0006885 | regulation of pH | biological_process | Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. [GOC:dph, GOC:go_curators, GOC:tb] |
| GO:0007420 | brain development | biological_process | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] |
| GO:0040008 | regulation of growth | biological_process | Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. [GOC:ems, GOC:mah] |
| GO:0032501 | multicellular organismal process | biological_process | Any biological process, occurring at the level of a multicellular organism, pertinent to its function. [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] |
| GO:0030163 | protein catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. [GOC:mah] |
| GO:0030424 | axon | cellular_component | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. [GOC:nln, ISBN:0198506732] |
| GO:0009117 | nucleotide metabolic process | biological_process | The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). [GOC:ma] |
| GO:0042592 | homeostatic process | biological_process | Any biological process involved in the maintenance of an internal steady state. [GOC:jl, ISBN:0395825172] |
| GO:0090407 | organophosphate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. [GOC:chem_mtg] |
| GO:0042981 | regulation of apoptotic process | biological_process | Any process that modulates the occurrence or rate of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| GO:0048878 | chemical homeostasis | biological_process | Any biological process involved in the maintenance of an internal steady state of a chemical. [GOC:isa_complete] |
| GO:0065007 | biological regulation | biological_process | Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] |
| GO:0051049 | regulation of transport | biological_process | Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai] |
| GO:0016788 | hydrolase activity, acting on ester bonds | molecular_function | Catalysis of the hydrolysis of any ester bond. [GOC:jl] |
| GO:0043231 | intracellular membrane-bounded organelle | cellular_component | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators] |
| GO:0051234 | establishment of localization | biological_process | Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. [GOC:ai, GOC:dos] |
| GO:0065008 | regulation of biological quality | biological_process | Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] |
| GO:0060627 | regulation of vesicle-mediated transport | biological_process | Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. [GOC:dph, GOC:tb] |
| GO:0019693 | ribose phosphate metabolic process | biological_process | The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. [GOC:ai] |
| GO:0044267 | cellular protein metabolic process | biological_process | The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. [GOC:jl] |
| GO:0042157 | lipoprotein metabolic process | biological_process | The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. [ISBN:0198506732] |
| GO:0006725 | cellular aromatic compound metabolic process | biological_process | The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. [GOC:ai, ISBN:0198506732] |
| GO:0006637 | acyl-CoA metabolic process | biological_process | The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group. [ISBN:0198506732] |
| GO:0071704 | organic substance metabolic process | biological_process | The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. [GOC:mah] |
| GO:0015031 | protein transport | biological_process | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005764 | lysosome | cellular_component | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. [GOC:mah, ISBN:0198506732] |
| GO:0008021 | synaptic vesicle | cellular_component | A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. [PMID:10099709, PMID:12563290] |
| GO:0051130 | positive regulation of cellular component organization | biological_process | Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. [GOC:ai] |
| GO:0051336 | regulation of hydrolase activity | biological_process | Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [GOC:ai] |
| GO:0006796 | phosphate-containing compound metabolic process | biological_process | The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. [GOC:ai] |
| GO:1901566 | organonitrogen compound biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of organonitrogen compound. [GOC:pr, GOC:TermGenie] |
| GO:1901137 | carbohydrate derivative biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of carbohydrate derivative. [GOC:TermGenie] |
| GO:0001558 | regulation of cell growth | biological_process | Any process that modulates the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:1901214 | regulation of neuron death | biological_process | Any process that modulates the frequency, rate or extent of neuron death. [GOC:rph, GOC:TermGenie] |
| GO:0008152 | metabolic process | biological_process | The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [GOC:go_curators, ISBN:0198547684] |
| GO:0050794 | regulation of cellular process | biological_process | Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators] |
| GO:0031982 | vesicle | cellular_component | Any small, fluid-filled, spherical organelle enclosed by membrane. [GOC:mah, GOC:pz, GOC:vesicles] |
| GO:0009260 | ribonucleotide biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
| GO:0034654 | nucleobase-containing compound biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:mah] |
| GO:0046483 | heterocycle metabolic process | biological_process | The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). [ISBN:0198506732] |
| GO:0043167 | ion binding | molecular_function | Binding to an ion, a charged atoms or groups of atoms. [GOC:jl] |
| GO:0006139 | nucleobase-containing compound metabolic process | biological_process | Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:ai] |
| GO:0006897 | endocytosis | biological_process | A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. [GOC:mah, ISBN:0198506732, ISBN:0716731363] |
| GO:0016192 | vesicle-mediated transport | biological_process | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. [GOC:ai, GOC:mah, ISBN:08789310662000] |
| GO:0031974 | membrane-enclosed lumen | cellular_component | The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. [GOC:add, GOC:mah] |
| GO:1901565 | organonitrogen compound catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. [GOC:pr, GOC:TermGenie] |
| GO:0007610 | behavior | biological_process | The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] |
| GO:0006807 | nitrogen compound metabolic process | biological_process | The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. [GOC:jl, ISBN:0198506732] |
| GO:0005794 | Golgi apparatus | cellular_component | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. [ISBN:0198506732] |
| GO:1901362 | organic cyclic compound biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of organic cyclic compound. [GOC:TermGenie] |
| GO:0055067 | monovalent inorganic cation homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell. [GOC:ai, GOC:jid, GOC:mah] |
| GO:0019438 | aromatic compound biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. [GOC:ai] |
| GO:0005543 | phospholipid binding | molecular_function | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. [ISBN:0198506732] |
| GO:0060191 | regulation of lipase activity | biological_process | Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. [GOC:dph, GOC:tb] |
| GO:0044249 | cellular biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [GOC:jl] |
| GO:0043170 | macromolecule metabolic process | biological_process | The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:mah] |
| GO:0055080 | cation homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of cations within an organism or cell. [GOC:ceb, GOC:jid, GOC:mah] |
| GO:0006873 | cellular ion homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of ions at the level of a cell. [GOC:mah] |
| GO:0006793 | phosphorus metabolic process | biological_process | The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). [GOC:ai] |
| GO:0043226 | organelle | cellular_component | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. [GOC:go_curators] |
| GO:0016787 | hydrolase activity | molecular_function | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [ISBN:0198506732] |
| GO:0043067 | regulation of programmed cell death | biological_process | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. [GOC:jl] |
| GO:0034641 | cellular nitrogen compound metabolic process | biological_process | The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. [GOC:mah] |
| GO:0010517 | regulation of phospholipase activity | biological_process | Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0043412 | macromolecule modification | biological_process | The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. [GOC:go_curators] |
| GO:0051050 | positive regulation of transport | biological_process | Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai] |
| GO:0098771 | inorganic ion homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. [GOC:dos] |
| GO:0043066 | negative regulation of apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| GO:0006464 | cellular protein modification process | biological_process | The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). [GOC:go_curators] |
| GO:0006790 | sulfur compound metabolic process | biological_process | The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. [GOC:ai] |
| GO:0043233 | organelle lumen | cellular_component | The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. [GOC:jl, GOC:mah] |
| GO:0003008 | system process | biological_process | A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. [GOC:mtg_cardio] |
| GO:0044257 | cellular protein catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. [GOC:jl] |
| GO:1901564 | organonitrogen compound metabolic process | biological_process | The chemical reactions and pathways involving organonitrogen compound. [GOC:pr, GOC:TermGenie] |
| GO:0048259 | regulation of receptor-mediated endocytosis | biological_process | Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. [GOC:go_curators, GOC:tb] |
| GO:0006810 | transport | biological_process | The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. [GOC:dos, GOC:dph, GOC:jl, GOC:mah] |
| GO:0050789 | regulation of biological process | biological_process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators] |
| GO:0044238 | primary metabolic process | biological_process | The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. [GOC:go_curators, http://www.metacyc.org] |
| GO:0044271 | cellular nitrogen compound biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. [GOC:jl, ISBN:0198506732] |
| GO:0048522 | positive regulation of cellular process | biological_process | Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid] |
| GO:0045851 | pH reduction | biological_process | Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion. [GOC:go_curators] |
| GO:0008289 | lipid binding | molecular_function | Binding to a lipid. [GOC:ai] |
| GO:0098732 | macromolecule deacylation | biological_process | The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule. [GOC:dos] |
| GO:0006163 | purine nucleotide metabolic process | biological_process | The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732] |
| GO:0030149 | sphingolipid catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:mah, ISBN:0198506732] |
| GO:0043227 | membrane-bounded organelle | cellular_component | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators] |
| GO:0007600 | sensory perception | biological_process | The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. [GOC:ai, GOC:dph] |
| GO:0044281 | small molecule metabolic process | biological_process | The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:pde, GOC:vw] |
| GO:0016043 | cellular component organization | biological_process | A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:ai, GOC:jl, GOC:mah] |
| GO:0030004 | cellular monovalent inorganic cation homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell. [GOC:ai, GOC:mah] |
| GO:0050890 | cognition | biological_process | The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. [ISBN:0721619908] |
| GO:0016042 | lipid catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [GOC:go_curators] |
| GO:0009987 | cellular process | biological_process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete] |
| GO:0070013 | intracellular organelle lumen | cellular_component | An organelle lumen that is part of an intracellular organelle. [GOC:mah] |
| GO:0030641 | regulation of cellular pH | biological_process | Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment. [GOC:dph, GOC:mah, GOC:tb] |
| GO:0051453 | regulation of intracellular pH | biological_process | Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion. [GOC:ai, GOC:dph, GOC:tb] |
| GO:0030100 | regulation of endocytosis | biological_process | Any process that modulates the frequency, rate or extent of endocytosis. [GOC:go_curators] |
| GO:0050803 | regulation of synapse structure or activity | biological_process | Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). [GOC:ai] |
| GO:0043168 | anion binding | molecular_function | Binding to an anion, a charged atom or group of atoms with a net negative charge. [GOC:jl] |
| GO:0051128 | regulation of cellular component organization | biological_process | Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. [GOC:ai] |
| GO:0065009 | regulation of molecular function | biological_process | Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. [GOC:isa_complete] |
| GO:0140096 | catalytic activity, acting on a protein | molecular_function | Catalytic activity that acts to modify a protein. [GOC:molecular_function_refactoring, GOC:pdt] |
| GO:0046390 | ribose phosphate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar. [GOC:ai] |
| GO:0055082 | cellular chemical homeostasis | biological_process | Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell. [GOC:isa_complete, GOC:jid] |
| GO:0048518 | positive regulation of biological process | biological_process | Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid] |
| GO:0051452 | intracellular pH reduction | biological_process | Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion. [GOC:ai] |
| GO:0019725 | cellular homeostasis | biological_process | Any process involved in the maintenance of an internal steady state at the level of the cell. [GOC:isa_complete, GOC:jl, ISBN:0395825172] |
| GO:0060548 | negative regulation of cell death | biological_process | Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0009259 | ribonucleotide metabolic process | biological_process | The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732] |
| GO:0051179 | localization | biological_process | Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. [GOC:ai, GOC:dos] |
| GO:1901575 | organic substance catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon. [GOC:pr, GOC:TermGenie] |
| GO:0043604 | amide biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. [GOC:curators] |
| GO:0048666 | neuron development | biological_process | The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GOC:dph] |
| GO:0044260 | cellular macromolecule metabolic process | biological_process | The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. [GOC:mah] |
| GO:0007399 | nervous system development | biological_process | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. [GOC:dgh] |
| GO:1901576 | organic substance biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. [GOC:pr, GOC:TermGenie] |
| GO:0097367 | carbohydrate derivative binding | molecular_function | Binding to a carbohydrate derivative. [GOC:pr] |
| GO:0050896 | response to stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. [GOC:ai, GOC:bf] |
| GO:0043069 | negative regulation of programmed cell death | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. [GOC:jl] |
| GO:1901293 | nucleoside phosphate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. [GOC:TermGenie] |
| GO:0050790 | regulation of catalytic activity | biological_process | Any process that modulates the activity of an enzyme. [GOC:ai, GOC:ebc, GOC:vw] |
| GO:0048523 | negative regulation of cellular process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid] |
| GO:0019637 | organophosphate metabolic process | biological_process | The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound. [ISBN:0198506732] |
| GO:1901568 | fatty acid derivative metabolic process | biological_process | The chemical reactions and pathways involving fatty acid derivative. [GOC:pr, GOC:TermGenie] |
| GO:0110165 | cellular anatomical entity | cellular_component | A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. [GOC:kmv] |
| GO:1901135 | carbohydrate derivative metabolic process | biological_process | The chemical reactions and pathways involving carbohydrate derivative. [GOC:TermGenie] |
| GO:0032879 | regulation of localization | biological_process | Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. [GOC:mah] |
| GO:0009056 | catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. [ISBN:0198547684] |
| GO:0030425 | dendrite | cellular_component | A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. [GOC:aruk, GOC:bc, GOC:dos, GOC:mah, GOC:nln, ISBN:0198506732] |
| GO:0009057 | macromolecule catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:mah] |
| GO:1901360 | organic cyclic compound metabolic process | biological_process | The chemical reactions and pathways involving organic cyclic compound. [GOC:TermGenie] |
| GO:0045121 | membrane raft | cellular_component | Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. [PMID:16645198, PMID:20044567] |
| GO:0009150 | purine ribonucleotide metabolic process | biological_process | The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732] |
| GO:0071840 | cellular component organization or biogenesis | biological_process | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:mah] |
| GO:0055086 | nucleobase-containing small molecule metabolic process | biological_process | The cellular chemical reactions and pathways involving a nucleobase-containing small molecule |
| GO:0044237 | cellular metabolic process | biological_process | The chemical reactions and pathways by which individual cells transform chemical substances. [GOC:go_curators] |
| GO:0035601 | protein deacylation | biological_process | The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid. [GOC:se, PMID:12080046] |
| GO:0050801 | ion homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of ions within an organism or cell. [GOC:ai] |
| GO:0003824 | catalytic activity | molecular_function | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732] |
| GO:0009165 | nucleotide biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). [GOC:go_curators] |
| GO:0018130 | heterocycle biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). [ISBN:0198547684] |
| GO:0072521 | purine-containing compound metabolic process | biological_process | The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. [GOC:mah] |
| GO:0043025 | neuronal cell body | cellular_component | The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. [GOC:go_curators] |
| GO:0009152 | purine ribonucleotide biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732] |
| GO:0005488 | binding | molecular_function | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732] |
| GO:0006898 | receptor-mediated endocytosis | biological_process | An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. [GOC:mah, ISBN:0716731363] |
| GO:0043603 | cellular amide metabolic process | biological_process | The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. [GOC:curators] |
| GO:0030003 | cellular cation homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of cations at the level of a cell. [GOC:ceb, GOC:mah] |
| GO:0061024 | membrane organization | biological_process | A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. [GOC:dph, GOC:tb] |
| GO:0048519 | negative regulation of biological process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid] |
| GO:0050877 | nervous system process | biological_process | A organ system process carried out by any of the organs or tissues of neurological system. [GOC:ai, GOC:mtg_cardio] |
| GO:0019538 | protein metabolic process | biological_process | The chemical reactions and pathways involving a protein. Includes protein modification. [GOC:ma] |
| GO:0006753 | nucleoside phosphate metabolic process | biological_process | The chemical reactions and pathways involving any phosphorylated nucleoside. [GOC:mah] |
| GO:0010941 | regulation of cell death | biological_process | Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. [GOC:dph, GOC:tb] |
| GO:0007035 | vacuolar acidification | biological_process | Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion. [GOC:jid] |
| GO:0016790 | thiolester hydrolase activity | molecular_function | Catalysis of the reaction |