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Total number of protein in "GO:0072521" GO term:  261

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AADAT_ENST00000515480 AADAT Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial chr4 GO:0072521 Not Cancer Driver No 48 0.113 71 10 0.141 0
AASS AASS Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 GO:0072521 Not Cancer Driver No 161 0.174 18 3 0.167 0
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0072521 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABHD14B_ENST00000525795 ABHD14B Q96IU4 Putative protein-lysine deacylase ABHD14B chr3 GO:0072521 Not Cancer Driver No 12 0.057 17 2 0.118 0
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0072521 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0072521 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 GO:0072521 Not Cancer Driver No 120 0.109 114 12 0.105 0
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 GO:0072521 Not Cancer Driver No 93 0.168 41 3 0.073 0
ACOT4 ACOT4 Q8N9L9 Peroxisomal succinyl-coenzyme A thioesterase chr14 GO:0072521 Not Cancer Driver No 53 0.126 13 1 0.077 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0072521 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0072521 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0072521 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0072521 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACSF3_ENST00000406948 ACSF3 Q4G176 Malonate--CoA ligase ACSF3, mitochondrial chr16 GO:0072521 Not Cancer Driver No 87 0.151 48 11 0.229 9
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0072521 Not Cancer Driver No 85 0.122 27 1 0.037 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0072521 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0072521 Not Cancer Driver No 97 0.136 77 12 0.156 1
ACSL5_ENST00000354655 ACSL5 Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 chr10 GO:0072521 Not Cancer Driver No 98 0.143 22 5 0.227 0
ACSL6_ENST00000379240 ACSL6 Q9UKU0 Long-chain-fatty-acid--CoA ligase 6 chr5 GO:0072521 Census Yes 120 0.172 34 3 0.088 0
ACSM2A_ENST00000219054 ACSM2A Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial chr16 GO:0072521 Not Cancer Driver No 200 0.347 48 24 0.5 0
ACSS1 ACSS1 Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial chr20 GO:0072521 Not Cancer Driver No 79 0.115 76 6 0.079 0
ACSS2_ENST00000360596 ACSS2 Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic chr20 GO:0072521 Not Cancer Driver No 62 0.088 111 6 0.054 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0072521 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADA2 ADA2 Q9NZK5 Adenosine deaminase 2 chr22 GO:0072521 Not Cancer Driver No 97 0.19 1 0 0.0 10
ADAL ADAL Q6DHV7 Adenosine deaminase-like protein chr15 GO:0072521 Not Cancer Driver No 33 0.093 57 9 0.158 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0072521 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0072521 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0072521 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0072521 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0072521 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0072521 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0072521 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0072521 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0072521 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 GO:0072521 Not Cancer Driver No 195 0.144 271 42 0.155 0
ADK ADK P55263 Adenosine kinase chr10 GO:0072521 Not Cancer Driver No 29 0.08 33 2 0.061 3
ADPGK ADPGK Q9BRR6 ADP-dependent glucokinase chr15 GO:0072521 Not Cancer Driver No 38 0.076 24 0 0.0 0
ADSL ADSL P30566 Adenylosuccinate lyase chr22 GO:0072521 Not Cancer Driver No 68 0.14 36 9 0.25 27
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0072521 Not Cancer Driver No 49 0.107 48 4 0.083 0
ADSSL1_ENST00000330877 ADSS1 Q8N142 Adenylosuccinate synthetase isozyme 1 chr14 GO:0072521 Not Cancer Driver No 74 0.162 68 6 0.088 1
AK1_ENST00000373176 AK1 P00568 Adenylate kinase isoenzyme 1 chr9 GO:0072521 Not Cancer Driver No 19 0.098 55 3 0.055 4
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 GO:0072521 Not Cancer Driver No 23 0.096 76 12 0.158 2
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 GO:0072521 Not Cancer Driver No 23 0.101 33 3 0.091 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 GO:0072521 Not Cancer Driver No 26 0.117 24 3 0.125 0
AK5 AK5 Q9Y6K8 Adenylate kinase isoenzyme 5 chr1 GO:0072521 Not Cancer Driver No 116 0.206 161 44 0.273 0
AK9 AK9 Q5TCS8 Adenylate kinase 9 chr6 GO:0072521 Not Cancer Driver No 235 0.123 589 58 0.098 0
AMD1 AMD1 P17707 S-adenosylmethionine decarboxylase proenzyme chr6 GO:0072521 Not Cancer Driver No 42 0.126 9 1 0.111 0
AMPD1 AMPD1 P23109 AMP deaminase 1 chr1 GO:0072521 Not Cancer Driver No 218 0.292 112 25 0.223 2
AMPD2_ENST00000528667 AMPD2 Q01433 AMP deaminase 2 chr1 GO:0072521 Not Cancer Driver No 93 0.106 275 27 0.098 3
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 GO:0072521 Not Cancer Driver No 132 0.172 207 38 0.184 10
AP000311.1 AP000311.1 H7C0C1 ATP synthase subunit O, mitochondrial (Fragment) chr21 GO:0072521 Not Cancer Driver No 27 0.112 27 5 0.185 0
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 GO:0072521 Not Cancer Driver No 16 0.089 0 0 0.0 8
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0072521 Census Yes 74 0.125 25 1 0.04 1
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0072521 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0072521 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 GO:0072521 Not Cancer Driver No 39 0.131 11 0 0.0 0
ATP5F1D_ENST00000591660 ATP5F1D P30049 ATP synthase subunit delta, mitochondrial chr19 GO:0072521 Not Cancer Driver No 7 0.042 5 1 0.2 2
ATP5F1E_ENST00000395663 ATP5F1E P56381 ATP synthase subunit epsilon, mitochondrial chr20 GO:0072521 Not Cancer Driver No 3 0.059 1 0 0.0 1
ATP5ME ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 GO:0072521 Not Cancer Driver No 6 0.087 18 2 0.111 0
ATP5MF ATP5MF P56134 ATP synthase subunit f, mitochondrial chr7 GO:0072521 Not Cancer Driver No 22 0.234 0 0 0.0 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 GO:0072521 Not Cancer Driver No 16 0.155 0 0 0.0 0
ATP5PB ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 GO:0072521 Not Cancer Driver No 37 0.145 2 0 0.0 0
ATP5PD ATP5PD O75947 ATP synthase subunit d, mitochondrial chr17 GO:0072521 Not Cancer Driver No 12 0.075 15 0 0.0 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 GO:0072521 Not Cancer Driver No 14 0.13 15 1 0.067 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 GO:0072521 Not Cancer Driver No 19 0.089 9 2 0.222 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0072521 Not Cancer Driver No 12 0.07 111 11 0.099 0
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 GO:0072521 Not Cancer Driver No 44 0.143 9 0 0.0 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0072521 Census, Compendium Yes 303 0.263 530 140 0.264 5
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0072521 Not Cancer Driver No 118 0.127 285 45 0.158 4
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 GO:0072521 Not Cancer Driver No 57 0.101 50 4 0.08 1
CROT_ENST00000331536 CROT Q9UKG9 Peroxisomal carnitine O-octanoyltransferase chr7 GO:0072521 Not Cancer Driver No 107 0.175 32 2 0.062 0
DCAKD DCAKD Q8WVC6 Dephospho-CoA kinase domain-containing protein chr17 GO:0072521 Not Cancer Driver No 31 0.134 2 0 0.0 0
DCK DCK P27707 Deoxycytidine kinase chr4 GO:0072521 Not Cancer Driver No 29 0.112 22 4 0.182 0
DGAT1 DGAT1 O75907 Diacylglycerol O-acyltransferase 1 chr8 GO:0072521 Not Cancer Driver No 52 0.107 62 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0072521 Not Cancer Driver No 56 0.144 17 2 0.118 0
DGUOK DGUOK Q16854 Deoxyguanosine kinase, mitochondrial chr2 GO:0072521 Not Cancer Driver No 25 0.09 17 1 0.059 6
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0072521 Not Cancer Driver No 204 0.13 396 53 0.134 0
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 GO:0072521 Not Cancer Driver No 63 0.097 294 42 0.143 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:0072521 Not Cancer Driver No 67 0.132 17 0 0.0 10
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0072521 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 GO:0072521 Not Cancer Driver No 224 0.257 303 107 0.353 0
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 GO:0072521 Not Cancer Driver No 53 0.117 190 32 0.168 1
DNPH1 DNPH1 O43598 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 chr6 GO:0072521 Not Cancer Driver No 15 0.086 49 3 0.061 0
DPYD DPYD Q12882 Dihydropyrimidine dehydrogenase [NADP(+)] chr1 GO:0072521 Not Cancer Driver No 303 0.296 77 23 0.299 3
EFL1 EFL1 Q7Z2Z2 Elongation factor-like GTPase 1 chr15 GO:0072521 Not Cancer Driver No 128 0.114 329 37 0.112 0
ELOVL1_ENST00000372458 ELOVL1 Q9BW60 Elongation of very long chain fatty acids protein 1 chr1 GO:0072521 Not Cancer Driver No 32 0.115 0 0 0.0 1
ELOVL2 ELOVL2 Q9NXB9 Elongation of very long chain fatty acids protein 2 chr6 GO:0072521 Not Cancer Driver No 57 0.193 8 2 0.25 0
ELOVL3 ELOVL3 Q9HB03 Elongation of very long chain fatty acids protein 3 chr10 GO:0072521 Not Cancer Driver No 42 0.156 1 1 1.0 0
ELOVL4 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 GO:0072521 Not Cancer Driver No 68 0.217 23 6 0.261 1
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0072521 Not Cancer Driver No 34 0.114 25 4 0.16 2
ELOVL6 ELOVL6 Q9H5J4 Elongation of very long chain fatty acids protein 6 chr4 GO:0072521 Not Cancer Driver No 40 0.151 0 0 0.0 0
ELOVL7_ENST00000425382 ELOVL7 A1L3X0 Elongation of very long chain fatty acids protein 7 chr5 GO:0072521 Not Cancer Driver No 41 0.146 10 2 0.2 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0072521 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:0072521 Not Cancer Driver No 48 0.111 12 2 0.167 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0072521 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 GO:0072521 Not Cancer Driver No 79 0.174 20 4 0.2 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 GO:0072521 Not Cancer Driver No 67 0.109 26 2 0.077 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0072521 Not Cancer Driver No 90 0.149 26 3 0.115 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0072521 Compendium Yes 171 0.175 187 39 0.209 3
FAR1 FAR1 Q8WVX9 Fatty acyl-CoA reductase 1 chr11 GO:0072521 Not Cancer Driver No 66 0.128 0 0 0.0 4
FAR2 FAR2 Q96K12 Fatty acyl-CoA reductase 2 chr12 GO:0072521 Not Cancer Driver No 63 0.122 0 0 0.0 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0072521 Not Cancer Driver No 28 0.107 0 0 0.0 1
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0072521 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0072521 Not Cancer Driver No 79 0.12 548 64 0.117 0
GALK1 GALK1 P51570 Galactokinase chr17 GO:0072521 Not Cancer Driver No 31 0.079 43 5 0.116 11
GART_ENST00000381815 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 GO:0072521 Not Cancer Driver No 96 0.095 50 6 0.12 0
GCDH_ENST00000591470 GCDH Q92947 Glutaryl-CoA dehydrogenase, mitochondrial chr19 GO:0072521 Not Cancer Driver No 57 0.13 37 5 0.135 58
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0072521 Not Cancer Driver No 88 0.189 73 14 0.192 107
GDA_ENST00000358399 GDA Q9Y2T3 Guanine deaminase chr9 GO:0072521 Not Cancer Driver No 86 0.189 22 7 0.318 0
GIMAP7 GIMAP7 Q8NHV1 GTPase IMAP family member 7 chr7 GO:0072521 Not Cancer Driver No 90 0.3 11 2 0.182 0
GLYAT GLYAT Q6IB77 Glycine N-acyltransferase chr11 GO:0072521 Not Cancer Driver No 75 0.253 9 2 0.222 0
GMPR GMPR P36959 GMP reductase 1 chr6 GO:0072521 Not Cancer Driver No 52 0.151 17 3 0.176 0
GMPR2_ENST00000399440 GMPR2 Q9P2T1 GMP reductase 2 chr14 GO:0072521 Not Cancer Driver No 30 0.086 9 1 0.111 0
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 GO:0072521 Census, Compendium Yes 88 0.127 76 10 0.132 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0072521 Not Cancer Driver No 42 0.119 11 0 0.0 1
GNMT GNMT Q14749 Glycine N-methyltransferase chr6 GO:0072521 Not Cancer Driver No 25 0.085 0 0 0.0 3
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:0072521 Not Cancer Driver No 75 0.112 263 26 0.099 0
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:0072521 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:0072521 Not Cancer Driver No 191 0.261 187 48 0.257 0
GUCY1B1_ENST00000264424 GUCY1B1 Q02153 Guanylate cyclase soluble subunit beta-1 chr4 GO:0072521 Not Cancer Driver No 103 0.166 83 20 0.241 0
GUCY2C GUCY2C P25092 Guanylyl cyclase C chr12 GO:0072521 Not Cancer Driver No 209 0.195 51 7 0.137 2
GUCY2D GUCY2D Q02846 Retinal guanylyl cyclase 1 chr17 GO:0072521 Not Cancer Driver No 138 0.125 205 34 0.166 32
GUCY2F GUCY2F P51841 Retinal guanylyl cyclase 2 chrX GO:0072521 Not Cancer Driver No 230 0.208 88 15 0.17 0
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 GO:0072521 Not Cancer Driver No 28 0.142 71 9 0.127 0
HACD1 HACD1 B0YJ81 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 chr10 GO:0072521 Not Cancer Driver No 74 0.257 63 21 0.333 0
HACD2 HACD2 Q6Y1H2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 chr3 GO:0072521 Not Cancer Driver No 16 0.063 14 0 0.0 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0072521 Not Cancer Driver No 127 0.138 75 16 0.213 6
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0072521 Not Cancer Driver No 138 0.15 77 7 0.091 0
HK3 HK3 P52790 Hexokinase-3 chr5 GO:0072521 Not Cancer Driver No 164 0.178 71 17 0.239 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0072521 Not Cancer Driver No 84 0.095 112 12 0.107 0
HMGCS1_ENST00000433297 HMGCS1 Q01581 Hydroxymethylglutaryl-CoA synthase, cytoplasmic chr5 GO:0072521 Not Cancer Driver No 64 0.123 74 10 0.135 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0072521 Not Cancer Driver No 92 0.181 29 4 0.138 19
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0072521 Not Cancer Driver No 22 0.101 3 0 0.0 62
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 GO:0072521 Not Cancer Driver No 32 0.103 9 0 0.0 0
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 GO:0072521 Not Cancer Driver No 99 0.135 82 12 0.146 4
HTD2_ENST00000461393 HTD2 P86397 Hydroxyacyl-thioester dehydratase type 2, mitochondrial chr3 GO:0072521 Not Cancer Driver No 1 0.006 0 0 0.0 0
ICMT ICMT O60725 Protein-S-isoprenylcysteine O-methyltransferase chr1 GO:0072521 Not Cancer Driver No 24 0.085 0 0 0.0 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 GO:0072521 Not Cancer Driver No 75 0.146 13 1 0.077 7
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 GO:0072521 Not Cancer Driver No 70 0.136 6 1 0.167 0
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 GO:0072521 Not Cancer Driver No 21 0.108 10 1 0.1 1
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0072521 Not Cancer Driver No 67 0.079 291 28 0.096 3
LRGUK LRGUK Q96M69 Leucine-rich repeat and guanylate kinase domain-containing protein chr7 GO:0072521 Not Cancer Driver No 145 0.176 204 37 0.181 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0072521 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAGI3 MAGI3 Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 chr1 GO:0072521 Not Cancer Driver No 154 0.104 1039 105 0.101 0
MCCC2 MCCC2 Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial chr5 GO:0072521 Not Cancer Driver No 60 0.107 25 2 0.08 52
MCEE MCEE Q96PE7 Methylmalonyl-CoA epimerase, mitochondrial chr2 GO:0072521 Not Cancer Driver No 19 0.108 9 0 0.0 0
MFN1 MFN1 Q8IWA4 Mitofusin-1 chr3 GO:0072521 Not Cancer Driver No 90 0.121 64 5 0.078 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0072521 Not Cancer Driver No 41 0.083 82 0 0.0 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0072521 Not Cancer Driver No 13 0.102 0 0 0.0 0
MPP1 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX GO:0072521 Not Cancer Driver No 79 0.17 194 33 0.17 0
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 GO:0072521 Not Cancer Driver No 37 0.131 15 0 0.0 0
MVD MVD P53602 Diphosphomevalonate decarboxylase chr16 GO:0072521 Not Cancer Driver No 47 0.117 49 10 0.204 3
MVK MVK Q03426 Mevalonate kinase chr12 GO:0072521 Not Cancer Driver No 50 0.126 25 0 0.0 38
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0072521 Not Cancer Driver No 11 0.072 10 0 0.0 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0072521 Not Cancer Driver No 13 0.086 11 1 0.091 0
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 GO:0072521 Not Cancer Driver No 10 0.059 4 0 0.0 0
NME4 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 GO:0072521 Not Cancer Driver No 13 0.07 41 4 0.098 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0072521 Not Cancer Driver No 17 0.08 6 0 0.0 0
NME6_ENST00000415053 NME6 O75414 Nucleoside diphosphate kinase 6 chr3 GO:0072521 Not Cancer Driver No 23 0.124 22 3 0.136 0
NME7 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 GO:0072521 Not Cancer Driver No 53 0.141 0 0 0.0 0
NME9_ENST00000333911 NME9 Q86XW9 Thioredoxin domain-containing protein 6 chr3 GO:0072521 Not Cancer Driver No 51 0.155 145 27 0.186 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0072521 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPPB NPPB P16860 Natriuretic peptides B chr1 GO:0072521 Not Cancer Driver No 31 0.231 104 28 0.269 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0072521 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0072521 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0072521 Not Cancer Driver No 144 0.138 89 18 0.202 20
NT5C NT5C Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type chr17 GO:0072521 Not Cancer Driver No 19 0.095 4 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0072521 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C1B NT5C1B Q96P26 Cytosolic 5'-nucleotidase 1B chr2 GO:0072521 Not Cancer Driver No 136 0.223 253 58 0.229 0
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 GO:0072521 Census Yes 57 0.102 85 8 0.094 0
NT5E NT5E P21589 5'-nucleotidase chr6 GO:0072521 Not Cancer Driver No 61 0.106 26 2 0.077 1
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX GO:0072521 Not Cancer Driver No 29 0.177 68 8 0.118 0
NUDT11 NUDT11 Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta chrX GO:0072521 Not Cancer Driver No 30 0.183 65 13 0.2 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0072521 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0072521 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT18 NUDT18 Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 chr8 GO:0072521 Not Cancer Driver No 22 0.068 39 3 0.077 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 GO:0072521 Not Cancer Driver No 27 0.072 131 5 0.038 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0072521 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUDT2_ENST00000346365 NUDT2 P50583 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] chr9 GO:0072521 Not Cancer Driver No 16 0.109 24 1 0.042 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0072521 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT4B NUDT4B A0A024RBG1 Diphosphoinositol polyphosphate phosphohydrolase NUDT4B chr1 GO:0072521 Not Cancer Driver No 2 0.011 53 0 0.0 0
NUDT4_ENST00000415493 NUDT4 Q9NZJ9 Diphosphoinositol polyphosphate phosphohydrolase 2 chr12 GO:0072521 Not Cancer Driver No 20 0.111 53 9 0.17 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0072521 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0072521 Not Cancer Driver No 22 0.093 69 10 0.145 0
NUDT9 NUDT9 Q9BW91 ADP-ribose pyrophosphatase, mitochondrial chr4 GO:0072521 Not Cancer Driver No 27 0.077 177 16 0.09 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 GO:0072521 Not Cancer Driver No 150 0.147 106 19 0.179 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0072521 Not Cancer Driver No 114 0.119 131 17 0.13 60
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 GO:0072521 Not Cancer Driver No 23 0.054 35 3 0.086 0
PANK1 PANK1 Q8TE04 Pantothenate kinase 1 chr10 GO:0072521 Not Cancer Driver No 62 0.104 248 17 0.069 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0072521 Not Cancer Driver No 46 0.081 206 14 0.068 30
PANK3 PANK3 Q9H999 Pantothenate kinase 3 chr5 GO:0072521 Not Cancer Driver No 41 0.111 0 0 0.0 0
PANK4 PANK4 Q9NVE7 4'-phosphopantetheine phosphatase chr1 GO:0072521 Not Cancer Driver No 92 0.119 71 15 0.211 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 GO:0072521 Not Cancer Driver No 94 0.151 82 14 0.171 0
PAPSS2_ENST00000361175 PAPSS2 O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 chr10 GO:0072521 Not Cancer Driver No 81 0.132 100 7 0.07 4
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0072521 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0072521 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0072521 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0072521 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4C PDE4C Q08493 cAMP-specific 3',5'-cyclic phosphodiesterase 4C chr19 GO:0072521 Not Cancer Driver No 122 0.171 362 61 0.169 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0072521 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0072521 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDE7A PDE7A Q13946 High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A chr8 GO:0072521 Not Cancer Driver No 49 0.102 30 7 0.233 0
PDE7B PDE7B Q9NP56 cAMP-specific 3',5'-cyclic phosphodiesterase 7B chr6 GO:0072521 Not Cancer Driver No 74 0.164 47 7 0.149 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0072521 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDE8B PDE8B O95263 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B chr5 GO:0072521 Not Cancer Driver No 144 0.163 208 19 0.091 1
PDE9A PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0072521 Not Cancer Driver No 91 0.153 160 34 0.212 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX GO:0072521 Not Cancer Driver No 70 0.179 43 6 0.14 20
PDHA2 PDHA2 P29803 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial chr4 GO:0072521 Not Cancer Driver No 163 0.42 41 17 0.415 0
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 GO:0072521 Not Cancer Driver No 32 0.089 4 0 0.0 2
PDHX PDHX O00330 Pyruvate dehydrogenase protein X component, mitochondrial chr11 GO:0072521 Not Cancer Driver No 62 0.124 179 28 0.156 0
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 GO:0072521 Not Cancer Driver No 157 0.117 380 36 0.095 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0072521 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0072521 Not Cancer Driver No 80 0.103 70 8 0.114 9
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:0072521 Not Cancer Driver No 133 0.17 43 10 0.233 0
PGM2 PGM2 Q96G03 Phosphopentomutase chr4 GO:0072521 Not Cancer Driver No 79 0.129 108 13 0.12 0
PIPOX PIPOX Q9P0Z9 Peroxisomal sarcosine oxidase chr17 GO:0072521 Not Cancer Driver No 52 0.133 21 3 0.143 0
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 GO:0072521 Not Cancer Driver No 38 0.198 3 0 0.0 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0072521 Not Cancer Driver No 38 0.131 29 2 0.069 5
PPAT PPAT Q06203 Amidophosphoribosyltransferase chr4 GO:0072521 Not Cancer Driver No 66 0.128 48 4 0.083 0
PPCDC PPCDC Q96CD2 Phosphopantothenoylcysteine decarboxylase chr15 GO:0072521 Not Cancer Driver No 13 0.064 6 0 0.0 0
PPCS PPCS Q9HAB8 Phosphopantothenate--cysteine ligase chr1 GO:0072521 Not Cancer Driver No 39 0.125 13 0 0.0 2
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0072521 Not Cancer Driver No 37 0.121 0 0 0.0 23
PPT2_ENST00000395523 PPT2 Q9UMR5 Lysosomal thioesterase PPT2 chr6 GO:0072521 Compendium Yes 45 0.149 0 0 0.0 0
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:0072521 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:0072521 Not Cancer Driver No 56 0.176 4 1 0.25 0
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 GO:0072521 Not Cancer Driver No 29 0.129 3 0 0.0 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0072521 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0072521 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTHLH_ENST00000539239 PTHLH P12272 Parathyroid hormone-related protein chr12 GO:0072521 Not Cancer Driver No 44 0.249 132 40 0.303 2
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0072521 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0072521 Not Cancer Driver No 20 0.093 14 1 0.071 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0072521 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 GO:0072521 Not Cancer Driver No 25 0.122 0 0 0.0 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0072521 Not Cancer Driver No 57 0.109 182 17 0.093 4
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0072521 Not Cancer Driver No 104 0.166 91 14 0.154 13
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 GO:0072521 Not Cancer Driver No 22 0.071 34 2 0.059 17
SLC25A16 SLC25A16 P16260 Graves disease carrier protein chr10 GO:0072521 Not Cancer Driver No 37 0.111 9 0 0.0 0
SLC26A1 SLC26A1 Q9H2B4 Sulfate anion transporter 1 chr4 GO:0072521 Not Cancer Driver No 54 0.077 86 7 0.081 2
SLC26A2 SLC26A2 P50443 Sulfate transporter chr5 GO:0072521 Not Cancer Driver No 71 0.096 41 3 0.073 9
SLC35B2 SLC35B2 Q8TB61 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 chr6 GO:0072521 Not Cancer Driver No 49 0.113 13 3 0.231 0
SLC35B3 SLC35B3 Q9H1N7 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 chr6 GO:0072521 Not Cancer Driver No 33 0.082 6 0 0.0 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0072521 Not Cancer Driver No 40 0.112 117 9 0.077 0
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 GO:0072521 Not Cancer Driver No 51 0.11 46 6 0.13 3
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 GO:0072521 Not Cancer Driver No 48 0.111 12 2 0.167 0
SULT1A1_ENST00000314752 SULT1A1 P50225 Sulfotransferase 1A1 chr16 GO:0072521 Not Cancer Driver No 69 0.234 14 3 0.214 0
SULT1A2 SULT1A2 P50226 Sulfotransferase 1A2 chr16 GO:0072521 Not Cancer Driver No 46 0.156 3 0 0.0 0
SULT1B1 SULT1B1 O43704 Sulfotransferase 1B1 chr4 GO:0072521 Not Cancer Driver No 82 0.277 15 7 0.467 0
SULT1C3 SULT1C3 Q6IMI6 Sulfotransferase 1C3 chr2 GO:0072521 Not Cancer Driver No 77 0.253 14 5 0.357 0
SULT1C4 SULT1C4 O75897 Sulfotransferase 1C4 chr2 GO:0072521 Not Cancer Driver No 57 0.189 19 5 0.263 0
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 GO:0072521 Not Cancer Driver No 76 0.259 15 5 0.333 0
SULT2A1 SULT2A1 Q06520 Sulfotransferase 2A1 chr19 GO:0072521 Not Cancer Driver No 50 0.175 0 0 0.0 0
SULT2B1 SULT2B1 O00204 Sulfotransferase 2B1 chr19 GO:0072521 Not Cancer Driver No 42 0.115 100 11 0.11 0
TDO2 TDO2 P48775 Tryptophan 2,3-dioxygenase chr4 GO:0072521 Not Cancer Driver No 64 0.158 31 9 0.29 1
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 GO:0072521 Not Cancer Driver No 41 0.133 0 0 0.0 1
THEM5 THEM5 Q8N1Q8 Acyl-coenzyme A thioesterase THEM5 chr1 GO:0072521 Not Cancer Driver No 39 0.158 1 0 0.0 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 GO:0072521 Not Cancer Driver No 149 0.125 919 113 0.123 1
TPST1 TPST1 O60507 Protein-tyrosine sulfotransferase 1 chr7 GO:0072521 Not Cancer Driver No 50 0.135 49 5 0.102 0
TPST2 TPST2 O60704 Protein-tyrosine sulfotransferase 2 chr22 GO:0072521 Not Cancer Driver No 47 0.125 48 6 0.125 0
TTR TTR P02766 Transthyretin chr18 GO:0072521 Not Cancer Driver No 28 0.19 25 8 0.32 75
URAD URAD A6NGE7 Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase chr13 GO:0072521 Not Cancer Driver No 14 0.081 21 0 0.0 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0072521 Not Cancer Driver No 279 0.209 134 24 0.179 1