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Total number of protein in "GO:0009057" GO term:  259

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 GO:0009057 Not Cancer Driver No 38 0.124 7 2 0.286 0
ABHD12_ENST00000339157 ABHD12 Q8N2K0 Lysophosphatidylserine lipase ABHD12 chr20 GO:0009057 Not Cancer Driver No 45 0.113 8 1 0.125 1
ABHD13 ABHD13 Q7L211 Protein ABHD13 chr13 GO:0009057 Not Cancer Driver No 53 0.157 0 0 0.0 0
ABHD17A_ENST00000292577 ABHD17A Q96GS6 Alpha/beta hydrolase domain-containing protein 17A chr19 GO:0009057 Not Cancer Driver No 35 0.113 20 5 0.25 0
ABHD17B_ENST00000333421 ABHD17B Q5VST6 Alpha/beta hydrolase domain-containing protein 17B chr9 GO:0009057 Not Cancer Driver No 35 0.122 0 0 0.0 0
ABHD17C ABHD17C Q6PCB6 Alpha/beta hydrolase domain-containing protein 17C chr15 GO:0009057 Not Cancer Driver No 21 0.064 53 0 0.0 0
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 GO:0009057 Not Cancer Driver No 504 0.316 374 128 0.342 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0009057 Not Cancer Driver No 288 0.149 235 38 0.162 0
AFG1L AFG1L Q8WV93 AFG1-like ATPase chr6 GO:0009057 Not Cancer Driver No 52 0.108 13 2 0.154 0
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 GO:0009057 Not Cancer Driver No 182 0.119 143 23 0.161 1
ANAPC1 ANAPC1 Q9H1A4 Anaphase-promoting complex subunit 1 chr2 GO:0009057 Not Cancer Driver No 206 0.106 263 33 0.125 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0009057 Not Cancer Driver No 70 0.087 54 1 0.019 0
ANAPC5 ANAPC5 Q9UJX4 Anaphase-promoting complex subunit 5 chr12 GO:0009057 Not Cancer Driver No 94 0.125 41 4 0.098 0
ANG ANG P03950 Angiogenin chr14 GO:0009057 Not Cancer Driver No 19 0.129 36 2 0.056 14
AOAH_ENST00000617537 AOAH P28039 Acyloxyacyl hydrolase chr7 GO:0009057 Not Cancer Driver No 111 0.193 68 10 0.147 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0009057 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOE APOE P02649 Apolipoprotein E chr19 GO:0009057 Not Cancer Driver No 25 0.079 124 6 0.048 12
ASCC2 ASCC2 Q9H1I8 Activating signal cointegrator 1 complex subunit 2 chr22 GO:0009057 Not Cancer Driver No 87 0.115 326 34 0.104 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0009057 Not Cancer Driver No 279 0.127 87 8 0.092 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0009057 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0009057 Census, Compendium Yes 469 0.153 225 39 0.173 41
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0009057 Not Cancer Driver No 41 0.1 122 13 0.107 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0009057 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0009057 Not Cancer Driver No 98 0.087 861 79 0.092 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0009057 Not Cancer Driver No 45 0.1 190 19 0.1 0
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0009057 Not Cancer Driver No 17 0.12 34 6 0.176 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0009057 Not Cancer Driver No 16 0.073 175 14 0.08 0
C2orf40 ECRG4 Q9H1Z8 Augurin chr2 GO:0009057 Not Cancer Driver No 37 0.25 23 11 0.478 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0009057 Not Cancer Driver No 68 0.095 32 2 0.062 1
CCDC115 CCDC115 Q96NT0 Coiled-coil domain-containing protein 115 chr2 GO:0009057 Not Cancer Driver No 21 0.117 89 8 0.09 2
CD44 CD44 P16070 CD44 antigen chr11 GO:0009057 Not Cancer Driver No 75 0.101 542 60 0.111 0
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 GO:0009057 Not Cancer Driver No 68 0.11 54 7 0.13 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0009057 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0009057 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC23 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 GO:0009057 Not Cancer Driver No 57 0.095 45 6 0.133 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 GO:0009057 Not Cancer Driver No 179 0.217 289 75 0.26 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0009057 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0009057 Not Cancer Driver No 64 0.122 241 25 0.104 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 GO:0009057 Not Cancer Driver No 222 0.15 1192 183 0.154 0
CELA1 CELA1 Q9UNI1 Chymotrypsin-like elastase family member 1 chr12 GO:0009057 Not Cancer Driver No 48 0.186 20 0 0.0 0
CELA2A CELA2A P08217 Chymotrypsin-like elastase family member 2A chr1 GO:0009057 Not Cancer Driver No 39 0.145 4 4 1.0 2
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 GO:0009057 Not Cancer Driver No 198 0.143 229 26 0.114 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0009057 Not Cancer Driver No 207 0.152 105 10 0.095 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0009057 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHI3L2 CHI3L2 Q15782 Chitinase-3-like protein 2 chr1 GO:0009057 Not Cancer Driver No 70 0.179 20 4 0.2 0
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 GO:0009057 Not Cancer Driver No 116 0.244 42 10 0.238 0
CHIT1 CHIT1 Q13231 Chitotriosidase-1 chr1 GO:0009057 Not Cancer Driver No 86 0.185 85 11 0.129 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0009057 Not Cancer Driver No 58 0.132 69 10 0.145 9
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0009057 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0009057 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0009057 Not Cancer Driver No 30 0.103 6 0 0.0 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0009057 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTBS CTBS Q01459 Di-N-acetylchitobiase chr1 GO:0009057 Not Cancer Driver No 40 0.104 0 0 0.0 0
CTSD CTSD P07339 Cathepsin D chr11 GO:0009057 Not Cancer Driver No 57 0.138 6 1 0.167 2
CTSL CTSL P07711 Procathepsin L chr9 GO:0009057 Not Cancer Driver No 47 0.141 34 4 0.118 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0009057 Census, Compendium Yes 123 0.16 167 23 0.138 3
DCAF12 DCAF12 Q5T6F0 DDB1- and CUL4-associated factor 12 chr9 GO:0009057 Not Cancer Driver No 59 0.13 70 7 0.1 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0009057 Not Cancer Driver No 57 0.136 167 24 0.144 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0009057 Not Cancer Driver No 48 0.142 53 6 0.113 1
DEDD2 DEDD2 Q8WXF8 DNA-binding death effector domain-containing protein 2 chr19 GO:0009057 Not Cancer Driver No 42 0.129 133 25 0.188 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0009057 Not Cancer Driver No 28 0.112 11 1 0.091 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0009057 Not Cancer Driver No 47 0.142 113 18 0.159 0
DFFB_ENST00000378209 DFFB O76075 DNA fragmentation factor subunit beta chr1 GO:0009057 Not Cancer Driver No 37 0.109 27 1 0.037 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0009057 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:0009057 Compendium Yes 121 0.126 235 32 0.136 0
DIS3L DIS3L Q8TF46 DIS3-like exonuclease 1 chr15 GO:0009057 Not Cancer Driver No 111 0.105 139 20 0.144 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0009057 Not Cancer Driver No 114 0.129 264 22 0.083 1
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0009057 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0009057 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0009057 Not Cancer Driver No 46 0.128 48 7 0.146 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 GO:0009057 Not Cancer Driver No 53 0.147 14 1 0.071 0
DPP7 DPP7 Q9UHL4 Dipeptidyl peptidase 2 chr9 GO:0009057 Not Cancer Driver No 41 0.083 29 0 0.0 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0009057 Census, Compendium Yes 175 0.127 682 100 0.147 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0009057 Not Cancer Driver No 46 0.116 143 17 0.119 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0009057 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0009057 Not Cancer Driver No 69 0.119 54 3 0.056 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0009057 Not Cancer Driver No 86 0.104 208 30 0.144 10
ENC1_ENST00000302351 ENC1 O14682 Ectoderm-neural cortex protein 1 chr5 GO:0009057 Not Cancer Driver No 85 0.144 8 0 0.0 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0009057 Not Cancer Driver No 11 0.037 61 1 0.016 0
ERI1_ENST00000519292 ERI1 Q8IV48 3'-5' exoribonuclease 1 chr8 GO:0009057 Not Cancer Driver No 40 0.115 78 13 0.167 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0009057 Not Cancer Driver No 192 0.207 213 45 0.211 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0009057 Not Cancer Driver No 42 0.114 52 1 0.019 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0009057 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0009057 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0009057 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0009057 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0009057 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0009057 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0009057 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0009057 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0009057 Not Cancer Driver No 58 0.132 154 18 0.117 1
FBXO17 FBXO17 Q96EF6 F-box only protein 17 chr19 GO:0009057 Not Cancer Driver No 30 0.108 3 1 0.333 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 GO:0009057 Not Cancer Driver No 21 0.071 75 1 0.013 0
FBXO27 FBXO27 Q8NI29 F-box only protein 27 chr19 GO:0009057 Not Cancer Driver No 37 0.131 33 3 0.091 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0009057 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO44_ENST00000251547 FBXO44 Q9H4M3 F-box only protein 44 chr1 GO:0009057 Not Cancer Driver No 30 0.118 27 3 0.111 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 GO:0009057 Not Cancer Driver No 31 0.106 27 3 0.111 0
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 GO:0009057 Not Cancer Driver No 68 0.102 162 22 0.136 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0009057 Not Cancer Driver No 69 0.11 33 3 0.091 0
FEM1C FEM1C Q96JP0 Protein fem-1 homolog C chr5 GO:0009057 Not Cancer Driver No 55 0.089 27 1 0.037 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0009057 Census Yes 35 0.092 111 11 0.099 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0009057 Not Cancer Driver No 18 0.062 183 5 0.027 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0009057 Census, Compendium Yes 39 0.104 257 20 0.078 26
FUCA1 FUCA1 P04066 Tissue alpha-L-fucosidase chr1 GO:0009057 Not Cancer Driver No 42 0.09 11 1 0.091 3
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0009057 Not Cancer Driver No 74 0.149 184 30 0.163 0
G6PC G6PC1 P35575 Glucose-6-phosphatase catalytic subunit 1 chr17 GO:0009057 Not Cancer Driver No 67 0.188 0 0 0.0 54
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 GO:0009057 Not Cancer Driver No 101 0.106 147 18 0.122 131
GLB1 GLB1 P16278 Beta-galactosidase chr3 GO:0009057 Not Cancer Driver No 72 0.106 54 6 0.111 99
GNS GNS P15586 N-acetylglucosamine-6-sulfatase chr12 GO:0009057 Not Cancer Driver No 48 0.087 22 0 0.0 3
GPC1 GPC1 P35052 Glypican-1 chr2 GO:0009057 Not Cancer Driver No 58 0.104 166 14 0.084 0
GPRASP1_ENST00000415986 GPRASP1 Q5JY77 G-protein coupled receptor-associated sorting protein 1 chrX GO:0009057 Not Cancer Driver No 217 0.156 918 133 0.145 0
GUSB GUSB P08236 Beta-glucuronidase chr7 GO:0009057 Not Cancer Driver No 93 0.143 11 0 0.0 36
HPSE HPSE Q9Y251 Heparanase chr4 GO:0009057 Not Cancer Driver No 90 0.166 16 2 0.125 0
HPSE2 HPSE2 Q8WWQ2 Inactive heparanase-2 chr10 GO:0009057 Not Cancer Driver No 123 0.208 42 20 0.476 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0009057 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0009057 Not Cancer Driver No 149 0.231 251 52 0.207 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0009057 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0009057 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYAL3 HYAL3 O43820 Hyaluronidase-3 chr3 GO:0009057 Not Cancer Driver No 48 0.115 10 0 0.0 0
HYAL4_ENST00000476325 HYAL4 Q2M3T9 Hyaluronidase-4 chr7 GO:0009057 Not Cancer Driver No 100 0.208 0 0 0.0 0
IDE IDE P14735 Insulin-degrading enzyme chr10 GO:0009057 Not Cancer Driver No 90 0.088 96 8 0.083 0
IDS IDS P22304 Iduronate 2-sulfatase chrX GO:0009057 Not Cancer Driver No 91 0.165 85 13 0.153 126
IDUA IDUA P35475 Alpha-L-iduronidase chr4 GO:0009057 Not Cancer Driver No 46 0.07 101 5 0.05 57
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0009057 Not Cancer Driver No 20 0.11 6 0 0.0 0
KIF16B_ENST00000354981 KIF16B Q96L93 Kinesin-like protein KIF16B chr20 GO:0009057 Not Cancer Driver No 248 0.188 436 74 0.17 0
KLHDC1 KLHDC1 Q8N7A1 Kelch domain-containing protein 1 chr14 GO:0009057 Not Cancer Driver No 36 0.089 37 7 0.189 0
KLHDC10 KLHDC10 Q6PID8 Kelch domain-containing protein 10 chr7 GO:0009057 Not Cancer Driver No 40 0.09 93 3 0.032 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 GO:0009057 Not Cancer Driver No 39 0.096 42 2 0.048 0
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 GO:0009057 Not Cancer Driver No 43 0.113 12 1 0.083 0
KLHL15 KLHL15 Q96M94 Kelch-like protein 15 chrX GO:0009057 Not Cancer Driver No 74 0.123 25 4 0.16 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX GO:0009057 Not Cancer Driver No 43 0.105 55 7 0.127 1
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0009057 Not Cancer Driver No 119 0.138 63 3 0.048 104
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0009057 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0009057 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0009057 Not Cancer Driver No 60 0.24 179 32 0.179 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0009057 Not Cancer Driver No 99 0.103 175 15 0.086 10
LSM1 LSM1 O15116 U6 snRNA-associated Sm-like protein LSm1 chr8 GO:0009057 Not Cancer Driver No 21 0.158 6 1 0.167 0
LTN1_ENST00000361371 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 GO:0009057 Not Cancer Driver No 192 0.109 124 23 0.185 0
LYG1 LYG1 Q8N1E2 Lysozyme g-like protein 1 chr2 GO:0009057 Not Cancer Driver No 18 0.093 36 4 0.111 0
LYG2 LYG2 Q86SG7 Lysozyme g-like protein 2 chr2 GO:0009057 Not Cancer Driver No 38 0.179 1 1 1.0 0
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 GO:0009057 Not Cancer Driver No 19 0.083 12 2 0.167 0
LYPLA2 LYPLA2 O95372 Acyl-protein thioesterase 2 chr1 GO:0009057 Not Cancer Driver No 22 0.095 13 2 0.154 0
LYPLAL1 LYPLAL1 Q5VWZ2 Lysophospholipase-like protein 1 chr1 GO:0009057 Not Cancer Driver No 30 0.127 2 0 0.0 0
LYVE1 LYVE1 Q9Y5Y7 Lymphatic vessel endothelial hyaluronic acid receptor 1 chr11 GO:0009057 Not Cancer Driver No 34 0.106 77 13 0.169 0
MANBA MANBA O00462 Beta-mannosidase chr4 GO:0009057 Not Cancer Driver No 108 0.123 10 0 0.0 3
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0009057 Census, Compendium Yes 56 0.114 297 37 0.125 0
MGAM_ENST00000475668 MGAM O43451 Maltase-glucoamylase chr7 GO:0009057 Not Cancer Driver No 708 0.257 315 94 0.298 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0009057 Not Cancer Driver No 100 0.213 29 5 0.172 0
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0009057 Not Cancer Driver No 37 0.111 45 2 0.044 1
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0009057 Not Cancer Driver No 73 0.125 136 22 0.162 1
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0009057 Not Cancer Driver No 117 0.112 160 15 0.094 0
MVB12A MVB12A Q96EY5 Multivesicular body subunit 12A chr19 GO:0009057 Not Cancer Driver No 27 0.099 67 4 0.06 0
NAGLU NAGLU P54802 Alpha-N-acetylglucosaminidase chr17 GO:0009057 Not Cancer Driver No 70 0.094 18 1 0.056 68
NCCRP1 NCCRP1 Q6ZVX7 F-box only protein 50 chr19 GO:0009057 Not Cancer Driver No 38 0.138 139 22 0.158 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0009057 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEMF NEMF O60524 Ribosome quality control complex subunit NEMF chr14 GO:0009057 Not Cancer Driver No 109 0.101 517 61 0.118 0
NEU2 NEU2 Q9Y3R4 Sialidase-2 chr2 GO:0009057 Not Cancer Driver No 88 0.232 144 32 0.222 0
NEU4_ENST00000407683 NEU4 Q8WWR8 Sialidase-4 chr2 GO:0009057 Not Cancer Driver No 82 0.169 199 37 0.186 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0009057 Census, Compendium Yes 228 0.377 402 62 0.154 4
NGLY1 NGLY1 Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase chr3 GO:0009057 Not Cancer Driver No 79 0.121 98 13 0.133 0
NOTUM NOTUM Q6P988 Palmitoleoyl-protein carboxylesterase NOTUM chr17 GO:0009057 Not Cancer Driver No 50 0.101 73 6 0.082 0
NT5C3B NT5C3B Q969T7 7-methylguanosine phosphate-specific 5'-nucleotidase chr17 GO:0009057 Not Cancer Driver No 25 0.083 2 0 0.0 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0009057 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0009057 Not Cancer Driver No 29 0.149 8 1 0.125 0
OGA OGA O60502 Protein O-GlcNAcase chr10 GO:0009057 Not Cancer Driver No 89 0.097 241 15 0.062 0
OVGP1 OVGP1 Q12889 Oviduct-specific glycoprotein chr1 GO:0009057 Not Cancer Driver No 109 0.161 272 40 0.147 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0009057 Not Cancer Driver No 71 0.111 197 22 0.112 2
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0009057 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0009057 Not Cancer Driver No 86 0.124 148 27 0.182 9
PCYOX1 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 GO:0009057 Not Cancer Driver No 60 0.119 9 1 0.111 0
PCYOX1L PCYOX1L Q8NBM8 Prenylcysteine oxidase-like chr5 GO:0009057 Not Cancer Driver No 61 0.123 0 0 0.0 0
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0009057 Not Cancer Driver No 59 0.097 129 8 0.062 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0009057 Not Cancer Driver No 38 0.099 67 10 0.149 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0009057 Not Cancer Driver No 80 0.103 70 8 0.114 9
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0009057 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0009057 Not Cancer Driver No 111 0.193 160 28 0.175 0
PGLYRP3 PGLYRP3 Q96LB9 Peptidoglycan recognition protein 3 chr1 GO:0009057 Not Cancer Driver No 81 0.238 0 0 0.0 0
PGLYRP4 PGLYRP4 Q96LB8 Peptidoglycan recognition protein 4 chr1 GO:0009057 Not Cancer Driver No 81 0.217 4 1 0.25 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0009057 Not Cancer Driver No 193 0.142 315 45 0.143 0
PISD_ENST00000439502 PISD Q9UG56 Phosphatidylserine decarboxylase proenzyme, mitochondrial chr22 GO:0009057 Not Cancer Driver No 42 0.103 8 3 0.375 2
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0009057 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0009057 Not Cancer Driver No 15 0.087 15 1 0.067 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0009057 Not Cancer Driver No 161 0.157 495 75 0.152 3
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0009057 Not Cancer Driver No 37 0.121 0 0 0.0 23
PRPF18 PRPF18 Q99633 Pre-mRNA-splicing factor 18 chr10 GO:0009057 Not Cancer Driver No 52 0.152 93 18 0.194 0
PSME4 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 GO:0009057 Not Cancer Driver No 214 0.116 134 12 0.09 0
PYGB PYGB P11216 Glycogen phosphorylase, brain form chr20 GO:0009057 Not Cancer Driver No 118 0.14 29 5 0.172 0
PYGL PYGL P06737 Glycogen phosphorylase, liver form chr14 GO:0009057 Not Cancer Driver No 98 0.116 23 2 0.087 2
PYGM PYGM P11217 Glycogen phosphorylase, muscle form chr11 GO:0009057 Not Cancer Driver No 153 0.182 39 4 0.103 17
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0009057 Not Cancer Driver No 27 0.13 11 0 0.0 4
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 GO:0009057 Not Cancer Driver No 202 0.127 578 75 0.13 0
RBM7_ENST00000540163 RBM7 Q9Y580 RNA-binding protein 7 chr11 GO:0009057 Not Cancer Driver No 36 0.135 194 27 0.139 0
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0009057 Not Cancer Driver No 34 0.081 298 26 0.087 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0009057 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0009057 Not Cancer Driver No 42 0.14 31 3 0.097 7
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0009057 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF126 RNF126 Q9BV68 E3 ubiquitin-protein ligase RNF126 chr19 GO:0009057 Not Cancer Driver No 33 0.106 182 22 0.121 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0009057 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF43_ENST00000577716 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 GO:0009057 Census, Compendium Yes 121 0.155 437 54 0.124 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0009057 Not Cancer Driver No 17 0.094 69 3 0.043 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 GO:0009057 Not Cancer Driver No 16 0.072 130 9 0.069 0
SGSH SGSH P51688 N-sulphoglucosamine sulphohydrolase chr17 GO:0009057 Not Cancer Driver No 45 0.09 44 2 0.045 56
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0009057 Not Cancer Driver No 41 0.112 82 10 0.122 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0009057 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0009057 Not Cancer Driver No 152 0.169 45 5 0.111 0
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0009057 Not Cancer Driver No 66 0.072 61 3 0.049 4
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0009057 Not Cancer Driver No 89 0.118 256 31 0.121 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0009057 Not Cancer Driver No 87 0.116 242 28 0.116 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 GO:0009057 Census Yes 127 0.14 258 48 0.186 0
SNX25 SNX25 Q9H3E2 Sorting nexin-25 chr4 GO:0009057 Not Cancer Driver No 101 0.12 114 10 0.088 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0009057 Not Cancer Driver No 33 0.082 91 13 0.143 0
SPAM1_ENST00000439500 SPAM1 P38567 Hyaluronidase PH-20 chr7 GO:0009057 Not Cancer Driver No 172 0.338 5 1 0.2 0
SPATA18 SPATA18 Q8TC71 Mitochondria-eating protein chr4 GO:0009057 Not Cancer Driver No 129 0.24 222 49 0.221 0
SSB SSB P05455 Lupus La protein chr2 GO:0009057 Not Cancer Driver No 39 0.096 181 18 0.099 0
STBD1 STBD1 O95210 Starch-binding domain-containing protein 1 chr4 GO:0009057 Not Cancer Driver No 47 0.131 229 31 0.135 0
STT3B STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 GO:0009057 Not Cancer Driver No 60 0.073 136 9 0.066 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0009057 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0009057 Not Cancer Driver No 72 0.092 140 12 0.086 0
SYNPO2_ENST00000429713 SYNPO2 Q9UMS6 Synaptopodin-2 chr4 GO:0009057 Not Cancer Driver No 240 0.22 978 219 0.224 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0009057 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0009057 Not Cancer Driver No 65 0.134 75 15 0.2 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0009057 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0009057 Not Cancer Driver No 61 0.132 219 34 0.155 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 GO:0009057 Not Cancer Driver No 31 0.113 56 4 0.071 1
TMEM199 TMEM199 Q8N511 Transmembrane protein 199 chr17 GO:0009057 Not Cancer Driver No 24 0.115 54 5 0.093 3
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0009057 Not Cancer Driver No 33 0.099 0 0 0.0 3
TPP1 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 GO:0009057 Not Cancer Driver No 67 0.119 92 7 0.076 37
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0009057 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0009057 Not Cancer Driver No 33 0.14 23 6 0.261 0
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 GO:0009057 Not Cancer Driver No 71 0.122 176 27 0.153 0
TRIR TRIR Q9BQ61 Telomerase RNA component interacting RNase chr19 GO:0009057 Not Cancer Driver No 17 0.097 176 17 0.097 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 GO:0009057 Not Cancer Driver No 84 0.105 70 7 0.1 0
TTC37 TTC37 Q6PGP7 Tetratricopeptide repeat protein 37 chr5 GO:0009057 Not Cancer Driver No 164 0.105 59 3 0.051 3
TUT1_ENST00000476907 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 GO:0009057 Not Cancer Driver No 97 0.111 410 50 0.122 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0009057 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0009057 Not Cancer Driver No 159 0.106 659 74 0.112 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0009057 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0009057 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0009057 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0009057 Not Cancer Driver No 172 0.098 228 30 0.132 0
UBR3 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 GO:0009057 Not Cancer Driver No 154 0.082 339 28 0.083 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0009057 Not Cancer Driver No 26 0.085 100 7 0.07 0
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 GO:0009057 Not Cancer Driver No 169 0.109 161 20 0.124 0
UGGT2 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 GO:0009057 Not Cancer Driver No 190 0.125 64 6 0.094 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0009057 Not Cancer Driver No 146 0.129 329 36 0.109 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0009057 Not Cancer Driver No 89 0.127 243 28 0.115 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0009057 Not Cancer Driver No 88 0.109 186 16 0.086 16
VPS13A VPS13A Q96RL7 Intermembrane lipid transfer protein VPS13A chr9 GO:0009057 Not Cancer Driver No 375 0.118 208 18 0.087 6
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0009057 Not Cancer Driver No 29 0.078 25 0 0.0 8
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0009057 Not Cancer Driver No 213 0.125 577 65 0.113 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0009057 Not Cancer Driver No 129 0.136 427 63 0.148 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 GO:0009057 Not Cancer Driver No 112 0.145 136 14 0.103 1
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0009057 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC8 ZCCHC8 Q6NZY4 Zinc finger CCHC domain-containing protein 8 chr12 GO:0009057 Census Yes 81 0.115 503 56 0.111 1
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0009057 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0009057 Compendium Yes 57 0.169 212 30 0.142 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0009057 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNRF3 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0009057 Census, Compendium Yes 94 0.1 510 51 0.1 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0009057 Not Cancer Driver No 38 0.083 291 27 0.093 0