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GLUL_ENST00000331872 ,GLUL ,P15104
  • Uniprot Accession= P15104
  • Ensembl Transcript= ENST00000331872.10
  • Uniprot Name= GLUL
  • Name= Glutamine synthetase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 117
GO term GO name GO namespace GO def
GO:0046883 regulation of hormone secretion biological_process Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. [GOC:ai]
GO:0046395 carboxylic acid catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. [ISBN:0198506732]
GO:0016595 glutamate binding molecular_function Binding to glutamate, the anion of 2-aminopentanedioic acid. [GOC:ai]
GO:0032880 regulation of protein localization biological_process Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. [GOC:dph, GOC:mah, GOC:tb]
GO:0043204 perikaryon cellular_component The portion of the cell soma (neuronal cell body) that excludes the nucleus. [GOC:jl]
GO:0046394 carboxylic acid biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. [ISBN:0198506732]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0065007 biological regulation biological_process Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups molecular_function Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). [GOC:jl]
GO:0099177 regulation of trans-synaptic signaling biological_process Any process that modulates the frequency, rate or extent of trans-synaptic signaling. [GOC:dos]
GO:0016740 transferase activity molecular_function Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. [ISBN:0198506732]
GO:0050896 response to stimulus biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. [GOC:ai, GOC:bf]
GO:0006082 organic acid metabolic process biological_process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. [ISBN:0198506732]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0008152 metabolic process biological_process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [GOC:go_curators, ISBN:0198547684]
GO:0050793 regulation of developmental process biological_process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:go_curators]
GO:0008283 cell population proliferation biological_process The multiplication or reproduction of cells, resulting in the expansion of a cell population. [GOC:mah, GOC:mb]
GO:0044238 primary metabolic process biological_process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. [GOC:go_curators, http://www.metacyc.org]
GO:1901566 organonitrogen compound biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of organonitrogen compound. [GOC:pr, GOC:TermGenie]
GO:0016053 organic acid biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. [ISBN:0198506732]
GO:0071704 organic substance metabolic process biological_process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. [GOC:mah]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0046887 positive regulation of hormone secretion biological_process Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. [GOC:ai]
GO:0005739 mitochondrion cellular_component A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]
GO:0023056 positive regulation of signaling biological_process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. [GOC:mtg_signal]
GO:0009056 catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. [ISBN:0198547684]
GO:0043169 cation binding molecular_function Binding to a cation, a charged atom or group of atoms with a net positive charge. [GOC:jl]
GO:0110165 cellular anatomical entity cellular_component A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. [GOC:kmv]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0043167 ion binding molecular_function Binding to an ion, a charged atoms or groups of atoms. [GOC:jl]
GO:0031982 vesicle cellular_component Any small, fluid-filled, spherical organelle enclosed by membrane. [GOC:mah, GOC:pz, GOC:vesicles]
GO:0044283 small molecule biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:pde, GOC:vw]
GO:0051223 regulation of protein transport biological_process Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0002791 regulation of peptide secretion biological_process Any process that modulates the frequency, rate, or extent of peptide secretion. [GOC:add]
GO:0050796 regulation of insulin secretion biological_process Any process that modulates the frequency, rate or extent of the regulated release of insulin. [GOC:ai]
GO:2000145 regulation of cell motility biological_process Any process that modulates the frequency, rate or extent of cell motility. [GOC:mah]
GO:0046872 metal ion binding molecular_function Binding to a metal ion. [GOC:ai]
GO:0001525 angiogenesis biological_process Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. [ISBN:0878932453]
GO:1901575 organic substance catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon. [GOC:pr, GOC:TermGenie]
GO:0003824 catalytic activity molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732]
GO:0051239 regulation of multicellular organismal process biological_process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai, GOC:dph, GOC:tb]
GO:0002793 positive regulation of peptide secretion biological_process Any process that activates or increases the frequency, rate, or extent of peptide secretion. [GOC:add]
GO:0050794 regulation of cellular process biological_process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators]
GO:0042221 response to chemical biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. [GOC:jl]
GO:0050708 regulation of protein secretion biological_process Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. [GOC:ai]
GO:0043227 membrane-bounded organelle cellular_component Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators]
GO:0045765 regulation of angiogenesis biological_process Any process that modulates the frequency, rate or extent of angiogenesis. [GOC:go_curators]
GO:0005791 rough endoplasmic reticulum cellular_component The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. [ISBN:0198506732]
GO:1901564 organonitrogen compound metabolic process biological_process The chemical reactions and pathways involving organonitrogen compound. [GOC:pr, GOC:TermGenie]
GO:0051966 regulation of synaptic transmission, glutamatergic biological_process Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. [GOC:ai]
GO:1903532 positive regulation of secretion by cell biological_process Any process that activates or increases the frequency, rate or extent of secretion by cell. [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530]
GO:0051270 regulation of cellular component movement biological_process Any process that modulates the frequency, rate or extent of the movement of a cellular component. [GOC:ai, GOC:dph, GOC:jl]
GO:0090277 positive regulation of peptide hormone secretion biological_process Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. [GOC:tb]
GO:0065008 regulation of biological quality biological_process Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
GO:0060341 regulation of cellular localization biological_process Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. [GOC:dph, GOC:tb]
GO:0050789 regulation of biological process biological_process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators]
GO:0090276 regulation of peptide hormone secretion biological_process Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. [GOC:tb]
GO:0051049 regulation of transport biological_process Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0006520 cellular amino acid metabolic process biological_process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells. [ISBN:0198506732]
GO:1901700 response to oxygen-containing compound biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. [GOC:pr, GOC:TermGenie]
GO:0005488 binding molecular_function The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732]
GO:0042995 cell projection cellular_component A prolongation or process extending from a cell, e.g. a flagellum or axon. [GOC:jl, http://www.cogsci.princeton.edu/~wn/]
GO:0010033 response to organic substance biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. [GOC:sm, PMID:23356676]
GO:0009058 biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [GOC:curators, ISBN:0198547684]
GO:0050806 positive regulation of synaptic transmission biological_process Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. [GOC:ai]
GO:0018345 protein palmitoylation biological_process The covalent attachment of a palmitoyl group to a protein. [GOC:jl, PMID:15520806]
GO:0032991 protein-containing complex cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah]
GO:0016874 ligase activity molecular_function Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. [EC:6.-.-.-, GOC:mah]
GO:0006807 nitrogen compound metabolic process biological_process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. [GOC:jl, ISBN:0198506732]
GO:0046914 transition metal ion binding molecular_function Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. [ISBN:0198506732]
GO:1901576 organic substance biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. [GOC:pr, GOC:TermGenie]
GO:1901342 regulation of vasculature development biological_process Any process that modulates the frequency, rate or extent of vasculature development. [GOC:TermGenie]
GO:0040012 regulation of locomotion biological_process Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. [GOC:ems]
GO:0010817 regulation of hormone levels biological_process Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. [GOC:BHF, GOC:dph, GOC:tb]
GO:0016409 palmitoyltransferase activity molecular_function Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. [GOC:ai]
GO:0043679 axon terminus cellular_component Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it. [GOC:dph, GOC:jl]
GO:0008652 cellular amino acid biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. [ISBN:0198506732]
GO:0050804 modulation of chemical synaptic transmission biological_process Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. [GOC:ai]
GO:0051047 positive regulation of secretion biological_process Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. [GOC:ai]
GO:0023051 regulation of signaling biological_process Any process that modulates the frequency, rate or extent of a signaling process. [GOC:mtg_signal]
GO:1903530 regulation of secretion by cell biological_process Any process that modulates the frequency, rate or extent of secretion by cell. [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530]
GO:0044249 cellular biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [GOC:jl]
GO:0030334 regulation of cell migration biological_process Any process that modulates the frequency, rate or extent of cell migration. [GOC:go_curators]
GO:0090087 regulation of peptide transport biological_process Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]
GO:0044282 small molecule catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:vw]
GO:0051050 positive regulation of transport biological_process Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0050679 positive regulation of epithelial cell proliferation biological_process Any process that activates or increases the rate or extent of epithelial cell proliferation. [GOC:ai]
GO:0016746 acyltransferase activity molecular_function Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). [GOC:jl, ISBN:0198506732]
GO:0050714 positive regulation of protein secretion biological_process Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. [GOC:ai]
GO:0010646 regulation of cell communication biological_process Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:dph, GOC:tb]
GO:0070201 regulation of establishment of protein localization biological_process Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. [GOC:BHF, GOC:mah]
GO:0010647 positive regulation of cell communication biological_process Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:dph, GOC:tb]
GO:0044248 cellular catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. [GOC:jl]
GO:0032879 regulation of localization biological_process Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. [GOC:mah]
GO:2000026 regulation of multicellular organismal development biological_process Any process that modulates the frequency, rate or extent of multicellular organismal development. [GOC:obol]
GO:0043436 oxoacid metabolic process biological_process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). [Wikipedia:Oxyacid]
GO:1901605 alpha-amino acid metabolic process biological_process The chemical reactions and pathways involving an alpha-amino acid. [GOC:TermGenie]
GO:0051046 regulation of secretion biological_process Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. [GOC:ai]
GO:0016054 organic acid catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. [ISBN:0198506732]
GO:0042254 ribosome biogenesis biological_process A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis]
GO:0022603 regulation of anatomical structure morphogenesis biological_process Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. [GOC:mah]
GO:0044281 small molecule metabolic process biological_process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:pde, GOC:vw]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0120025 plasma membrane bounded cell projection cellular_component A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. [GOC:krc]
GO:0009987 cellular process biological_process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete]
GO:0140096 catalytic activity, acting on a protein molecular_function Catalytic activity that acts to modify a protein. [GOC:molecular_function_refactoring, GOC:pdt]
GO:0048522 positive regulation of cellular process biological_process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid]
GO:0043226 organelle cellular_component Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. [GOC:go_curators]
GO:1901565 organonitrogen compound catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. [GOC:pr, GOC:TermGenie]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0009267 cellular response to starvation biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. [GOC:jl]
GO:0044237 cellular metabolic process biological_process The chemical reactions and pathways by which individual cells transform chemical substances. [GOC:go_curators]
GO:0019752 carboxylic acid metabolic process biological_process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). [ISBN:0198506732]
GO:0009063 cellular amino acid catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. [GOC:ai]
GO:0048518 positive regulation of biological process biological_process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid]
GO:0000287 magnesium ion binding molecular_function Binding to a magnesium (Mg) ion. [GOC:ai]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]