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Total number of protein in "GO:0046394" GO term:  204

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AASDHPPT AASDHPPT Q9NRN7 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase chr11 GO:0046394 Not Cancer Driver No 52 0.168 27 2 0.074 0
AASS AASS Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 GO:0046394 Not Cancer Driver No 161 0.174 18 3 0.167 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0046394 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0046394 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0046394 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 GO:0046394 Not Cancer Driver No 75 0.114 21 2 0.095 0
ABHD1 ABHD1 Q96SE0 Protein ABHD1 chr2 GO:0046394 Not Cancer Driver No 43 0.106 26 3 0.115 0
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0046394 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABHD3 ABHD3 Q8WU67 Phospholipase ABHD3 chr18 GO:0046394 Not Cancer Driver No 43 0.105 0 0 0.0 0
AC068533.4 AC068533.4 H7C0S8 Argininosuccinate lyase (Fragment) chr7 GO:0046394 Not Cancer Driver No 42 0.137 66 3 0.045 0
ACMSD ACMSD Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase chr2 GO:0046394 Not Cancer Driver No 65 0.193 9 2 0.222 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0046394 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 GO:0046394 Not Cancer Driver No 43 0.135 52 7 0.135 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0046394 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0046394 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACSS1 ACSS1 Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial chr20 GO:0046394 Not Cancer Driver No 79 0.115 76 6 0.079 0
ADI1 ADI1 Q9BV57 Acireductone dioxygenase chr2 GO:0046394 Not Cancer Driver No 27 0.151 23 1 0.043 0
AGXT AGXT P21549 Alanine--glyoxylate aminotransferase chr2 GO:0046394 Not Cancer Driver No 56 0.143 20 0 0.0 40
AGXT2 AGXT2 Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial chr5 GO:0046394 Not Cancer Driver No 136 0.265 11 5 0.455 0
AKR1A1_ENST00000621846 AKR1A1 P14550 Aldo-keto reductase family 1 member A1 chr1 GO:0046394 Not Cancer Driver No 40 0.123 26 4 0.154 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0046394 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKR1D1 AKR1D1 P51857 Aldo-keto reductase family 1 member D1 chr7 GO:0046394 Not Cancer Driver No 89 0.273 15 3 0.2 5
ALDH18A1 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 GO:0046394 Not Cancer Driver No 94 0.118 86 13 0.151 15
ALDH1A1 ALDH1A1 P00352 Aldehyde dehydrogenase 1A1 chr9 GO:0046394 Not Cancer Driver No 65 0.13 29 3 0.103 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0046394 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALDH1A3 ALDH1A3 P47895 Aldehyde dehydrogenase family 1 member A3 chr15 GO:0046394 Not Cancer Driver No 74 0.145 73 7 0.096 10
ALDH8A1 ALDH8A1 Q9H2A2 2-aminomuconic semialdehyde dehydrogenase chr6 GO:0046394 Not Cancer Driver No 107 0.22 40 6 0.15 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0046394 Not Cancer Driver No 73 0.11 73 12 0.164 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 GO:0046394 Not Cancer Driver No 101 0.144 16 3 0.188 18
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0046394 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0046394 Not Cancer Driver No 84 0.127 46 7 0.152 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0046394 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0046394 Not Cancer Driver No 17 0.106 1 0 0.0 0
ALOXE3_ENST00000448843 ALOXE3 Q9BYJ1 Hydroperoxide isomerase ALOXE3 chr17 GO:0046394 Not Cancer Driver No 108 0.152 69 13 0.188 6
AMACR_ENST00000335606 AMACR Q9UHK6 Alpha-methylacyl-CoA racemase chr5 GO:0046394 Not Cancer Driver No 56 0.147 38 8 0.211 3
APIP APIP Q96GX9 Methylthioribulose-1-phosphate dehydratase chr11 GO:0046394 Not Cancer Driver No 24 0.099 26 1 0.038 0
ASAH2 ASAH2 Q9NR71 Neutral ceramidase chr10 GO:0046394 Not Cancer Driver No 71 0.091 140 24 0.171 0
ASAH2B_ENST00000374006 ASAH2B P0C7U1 Putative inactive neutral ceramidase B chr10 GO:0046394 Not Cancer Driver No 9 0.055 14 1 0.071 0
ASL_ENST00000395332 ASL P04424 Argininosuccinate lyase chr7 GO:0046394 Not Cancer Driver No 77 0.166 36 2 0.056 63
ASNSD1 ASNSD1 Q9NWL6 Asparagine synthetase domain-containing protein 1 chr2 GO:0046394 Not Cancer Driver No 83 0.129 42 9 0.214 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0046394 Not Cancer Driver No 81 0.144 11 0 0.0 3
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0046394 Not Cancer Driver No 65 0.158 63 8 0.127 86
BAAT_ENST00000395051 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase chr9 GO:0046394 Not Cancer Driver No 88 0.211 10 4 0.4 1
BCAT1_ENST00000261192 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 GO:0046394 Not Cancer Driver No 67 0.174 8 2 0.25 0
BCAT2 BCAT2 O15382 Branched-chain-amino-acid aminotransferase, mitochondrial chr19 GO:0046394 Not Cancer Driver No 54 0.138 19 0 0.0 2
BHMT BHMT Q93088 Betaine--homocysteine S-methyltransferase 1 chr5 GO:0046394 Not Cancer Driver No 78 0.192 93 12 0.129 0
BHMT2 BHMT2 Q9H2M3 S-methylmethionine--homocysteine S-methyltransferase BHMT2 chr5 GO:0046394 Not Cancer Driver No 54 0.149 30 4 0.133 0
CAD CAD P27708 CAD protein chr2 GO:0046394 Not Cancer Driver No 287 0.129 368 52 0.141 1
CARNS1_ENST00000307823 CARNS1 A5YM72 Carnosine synthase 1 chr11 GO:0046394 Not Cancer Driver No 74 0.089 42 4 0.095 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0046394 Not Cancer Driver No 61 0.111 160 19 0.119 103
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0046394 Census Yes 31 0.105 185 20 0.108 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0046394 Not Cancer Driver No 368 0.245 73 22 0.301 140
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0046394 Not Cancer Driver No 27 0.196 23 6 0.261 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 GO:0046394 Not Cancer Driver No 45 0.111 49 6 0.122 2
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0046394 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0046394 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP27A1 CYP27A1 Q02318 Sterol 26-hydroxylase, mitochondrial chr2 GO:0046394 Not Cancer Driver No 69 0.13 47 11 0.234 7
CYP2C8 CYP2C8 P10632 Cytochrome P450 2C8 chr10 GO:0046394 Census, Compendium Yes 113 0.231 30 11 0.367 0
CYP2C9 CYP2C9 P11712 Cytochrome P450 2C9 chr10 GO:0046394 Not Cancer Driver No 122 0.249 36 14 0.389 0
CYP2D6_ENST00000645361 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0046394 Not Cancer Driver No 76 0.153 66 8 0.121 0
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0046394 Not Cancer Driver No 87 0.176 21 6 0.286 0
CYP39A1 CYP39A1 Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase chr6 GO:0046394 Not Cancer Driver No 61 0.13 3 0 0.0 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0046394 Not Cancer Driver No 91 0.181 22 2 0.091 1
CYP46A1 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0046394 Not Cancer Driver No 92 0.184 23 4 0.174 0
CYP4A11 CYP4A11 Q02928 Cytochrome P450 4A11 chr1 GO:0046394 Not Cancer Driver No 131 0.252 24 8 0.333 0
CYP4F11 CYP4F11 Q9HBI6 Cytochrome P450 4F11 chr19 GO:0046394 Not Cancer Driver No 132 0.252 11 2 0.182 0
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0046394 Not Cancer Driver No 109 0.216 48 8 0.167 0
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0046394 Not Cancer Driver No 133 0.263 0 0 0.0 11
CYP8B1 CYP8B1 Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase chr3 GO:0046394 Not Cancer Driver No 91 0.182 5 1 0.2 0
DAGLB DAGLB Q8NCG7 Diacylglycerol lipase-beta chr7 GO:0046394 Not Cancer Driver No 69 0.103 37 3 0.081 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0046394 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 GO:0046394 Not Cancer Driver No 25 0.134 20 0 0.0 0
DHRS9_ENST00000602501 DHRS9 Q9BPW9 Dehydrogenase/reductase SDR family member 9 chr2 GO:0046394 Not Cancer Driver No 67 0.21 3 0 0.0 0
DPYD DPYD Q12882 Dihydropyrimidine dehydrogenase [NADP(+)] chr1 GO:0046394 Not Cancer Driver No 303 0.296 77 23 0.299 3
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0046394 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0046394 Not Cancer Driver No 21 0.118 87 13 0.149 0
ELOVL1_ENST00000372458 ELOVL1 Q9BW60 Elongation of very long chain fatty acids protein 1 chr1 GO:0046394 Not Cancer Driver No 32 0.115 0 0 0.0 1
ELOVL2 ELOVL2 Q9NXB9 Elongation of very long chain fatty acids protein 2 chr6 GO:0046394 Not Cancer Driver No 57 0.193 8 2 0.25 0
ELOVL3 ELOVL3 Q9HB03 Elongation of very long chain fatty acids protein 3 chr10 GO:0046394 Not Cancer Driver No 42 0.156 1 1 1.0 0
ELOVL4 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 GO:0046394 Not Cancer Driver No 68 0.217 23 6 0.261 1
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0046394 Not Cancer Driver No 34 0.114 25 4 0.16 2
ELOVL6 ELOVL6 Q9H5J4 Elongation of very long chain fatty acids protein 6 chr4 GO:0046394 Not Cancer Driver No 40 0.151 0 0 0.0 0
ELOVL7_ENST00000425382 ELOVL7 A1L3X0 Elongation of very long chain fatty acids protein 7 chr5 GO:0046394 Not Cancer Driver No 41 0.146 10 2 0.2 0
ENOPH1 ENOPH1 Q9UHY7 Enolase-phosphatase E1 chr4 GO:0046394 Not Cancer Driver No 35 0.134 14 2 0.143 0
GAD1 GAD1 Q99259 Glutamate decarboxylase 1 chr2 GO:0046394 Not Cancer Driver No 113 0.19 55 5 0.091 1
GAMT_ENST00000252288 GAMT Q14353 Guanidinoacetate N-methyltransferase chr19 GO:0046394 Not Cancer Driver No 29 0.123 12 0 0.0 18
GATM GATM P50440 Glycine amidinotransferase, mitochondrial chr15 GO:0046394 Not Cancer Driver No 69 0.163 33 8 0.242 15
GGT1_ENST00000248923 GGT1 P19440 Glutathione hydrolase 1 proenzyme chr22 GO:0046394 Not Cancer Driver No 83 0.146 88 14 0.159 0
GGT2 GGT2P P36268 Inactive glutathione hydrolase 2 chr22 GO:0046394 Not Cancer Driver No 5 0.009 48 1 0.021 0
GGT5_ENST00000327365 GGT5 P36269 Glutathione hydrolase 5 proenzyme chr22 GO:0046394 Not Cancer Driver No 99 0.169 122 27 0.221 0
GGT6_ENST00000574154 GGT6 Q6P531 Glutathione hydrolase 6 chr17 GO:0046394 Not Cancer Driver No 51 0.103 211 32 0.152 0
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 GO:0046394 Not Cancer Driver No 77 0.116 170 14 0.082 0
GGTLC1_ENST00000278765 GGTLC1 Q9BX51 Glutathione hydrolase light chain 1 chr20 GO:0046394 Not Cancer Driver No 63 0.28 81 17 0.21 0
GGTLC2 GGTLC2 Q14390 Glutathione hydrolase light chain 2 chr22 GO:0046394 Not Cancer Driver No 25 0.115 119 11 0.092 0
GLS GLS O94925 Glutaminase kidney isoform, mitochondrial chr2 GO:0046394 Not Cancer Driver No 71 0.106 187 9 0.048 3
GLS2 GLS2 Q9UI32 Glutaminase liver isoform, mitochondrial chr12 GO:0046394 Not Cancer Driver No 57 0.095 108 9 0.083 0
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0046394 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUD2 GLUD2 P49448 Glutamate dehydrogenase 2, mitochondrial chrX GO:0046394 Not Cancer Driver No 145 0.26 117 37 0.316 0
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0046394 Not Cancer Driver No 66 0.177 104 21 0.202 2
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0046394 Not Cancer Driver No 56 0.136 35 5 0.143 0
GOT1L1 GOT1L1 Q8NHS2 Putative aspartate aminotransferase, cytoplasmic 2 chr8 GO:0046394 Not Cancer Driver No 62 0.147 0 0 0.0 0
GOT2 GOT2 P00505 Aspartate aminotransferase, mitochondrial chr16 GO:0046394 Not Cancer Driver No 61 0.142 25 3 0.12 1
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 GO:0046394 Not Cancer Driver No 14 0.071 0 0 0.0 0
GSTM1 GSTM1 P09488 Glutathione S-transferase Mu 1 chr1 GO:0046394 Not Cancer Driver No 17 0.078 7 1 0.143 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0046394 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTM4 GSTM4 Q03013 Glutathione S-transferase Mu 4 chr1 GO:0046394 Not Cancer Driver No 24 0.11 4 1 0.25 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0046394 Not Cancer Driver No 32 0.152 0 0 0.0 0
HAAO HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase chr2 GO:0046394 Not Cancer Driver No 40 0.14 30 2 0.067 0
HACD1 HACD1 B0YJ81 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 chr10 GO:0046394 Not Cancer Driver No 74 0.257 63 21 0.333 0
HACD2 HACD2 Q6Y1H2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 chr3 GO:0046394 Not Cancer Driver No 16 0.063 14 0 0.0 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 GO:0046394 Not Cancer Driver No 28 0.077 10 0 0.0 0
HACD4 HACD4 Q5VWC8 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 chr9 GO:0046394 Not Cancer Driver No 30 0.129 0 0 0.0 0
HOGA1 HOGA1 Q86XE5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial chr10 GO:0046394 Not Cancer Driver No 34 0.104 2 0 0.0 2
HPGDS HPGDS O60760 Hematopoietic prostaglandin D synthase chr4 GO:0046394 Not Cancer Driver No 34 0.171 0 0 0.0 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:0046394 Not Cancer Driver No 27 0.103 15 3 0.2 11
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 GO:0046394 Not Cancer Driver No 43 0.117 27 5 0.185 2
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0046394 Not Cancer Driver No 82 0.203 41 8 0.195 0
ILVBL ILVBL A1L0T0 2-hydroxyacyl-CoA lyase 2 chr19 GO:0046394 Not Cancer Driver No 86 0.136 30 1 0.033 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0046394 Not Cancer Driver No 77 0.158 0 0 0.0 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0046394 Not Cancer Driver No 103 0.222 20 5 0.25 1
LDHC LDHC P07864 L-lactate dehydrogenase C chain chr11 GO:0046394 Not Cancer Driver No 61 0.184 0 0 0.0 0
LGSN LGSN Q5TDP6 Lengsin chr6 GO:0046394 Not Cancer Driver No 136 0.267 91 22 0.242 0
LIAS LIAS O43766 Lipoyl synthase, mitochondrial chr4 GO:0046394 Not Cancer Driver No 46 0.124 82 10 0.122 1
LTA4H LTA4H P09960 Leukotriene A-4 hydrolase chr12 GO:0046394 Not Cancer Driver No 59 0.097 39 6 0.154 0
LTC4S LTC4S Q16873 Leukotriene C4 synthase chr5 GO:0046394 Not Cancer Driver No 3 0.02 0 0 0.0 0
MGST2 MGST2 Q99735 Microsomal glutathione S-transferase 2 chr4 GO:0046394 Not Cancer Driver No 11 0.075 0 0 0.0 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 GO:0046394 Not Cancer Driver No 17 0.112 0 0 0.0 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0046394 Not Cancer Driver No 4 0.035 0 0 0.0 0
MRI1 MRI1 Q9BV20 Methylthioribose-1-phosphate isomerase chr19 GO:0046394 Not Cancer Driver No 26 0.07 47 8 0.17 0
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 GO:0046394 Not Cancer Driver No 37 0.131 15 0 0.0 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0046394 Not Cancer Driver No 103 0.11 129 11 0.085 6
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 GO:0046394 Not Cancer Driver No 117 0.12 139 11 0.079 0
MTHFD2L MTHFD2L Q9H903 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial chr4 GO:0046394 Not Cancer Driver No 45 0.13 59 6 0.102 0
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 GO:0046394 Not Cancer Driver No 95 0.145 125 22 0.176 53
MTR MTR Q99707 Methionine synthase chr1 GO:0046394 Not Cancer Driver No 151 0.119 104 17 0.163 2
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 GO:0046394 Not Cancer Driver No 101 0.145 84 13 0.155 5
NAGS NAGS Q8N159 N-acetylglutamate synthase, mitochondrial chr17 GO:0046394 Not Cancer Driver No 35 0.066 116 6 0.052 6
NANP NANP Q8TBE9 N-acylneuraminate-9-phosphatase chr20 GO:0046394 Not Cancer Driver No 18 0.073 4 0 0.0 0
NOXRED1 NOXRED1 Q6NXP6 NADP-dependent oxidoreductase domain-containing protein 1 chr14 GO:0046394 Not Cancer Driver No 50 0.139 4 1 0.25 0
OAT OAT P04181 Ornithine aminotransferase, mitochondrial chr10 GO:0046394 Not Cancer Driver No 52 0.118 17 0 0.0 27
OLAH_ENST00000378228 OLAH Q9NV23 S-acyl fatty acid synthase thioesterase, medium chain chr10 GO:0046394 Not Cancer Driver No 53 0.2 44 13 0.295 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0046394 Not Cancer Driver No 83 0.103 386 39 0.101 0
OSBPL1A OSBPL1A Q9BXW6 Oxysterol-binding protein-related protein 1 chr18 GO:0046394 Not Cancer Driver No 110 0.116 314 27 0.086 0
OSBPL2_ENST00000643981 OSBPL2 Q9H1P3 Oxysterol-binding protein-related protein 2 chr20 GO:0046394 Not Cancer Driver No 57 0.119 173 18 0.104 0
OSBPL3 OSBPL3 Q9H4L5 Oxysterol-binding protein-related protein 3 chr7 GO:0046394 Not Cancer Driver No 114 0.129 324 44 0.136 0
OSBPL6_ENST00000190611 OSBPL6 Q9BZF3 Oxysterol-binding protein-related protein 6 chr2 GO:0046394 Not Cancer Driver No 167 0.179 365 72 0.197 0
OSBPL7_ENST00000392507 OSBPL7 Q9BZF2 Oxysterol-binding protein-related protein 7 chr17 GO:0046394 Not Cancer Driver No 99 0.118 395 44 0.111 0
OSBPL9_ENST00000428468 OSBPL9 Q96SU4 Oxysterol-binding protein-related protein 9 chr1 GO:0046394 Not Cancer Driver No 90 0.122 237 32 0.135 0
OTC OTC P00480 Ornithine transcarbamylase, mitochondrial chrX GO:0046394 Not Cancer Driver No 89 0.251 24 4 0.167 111
OXSM OXSM Q9NWU1 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial chr3 GO:0046394 Not Cancer Driver No 62 0.135 44 6 0.136 0
PAH PAH P00439 Phenylalanine-4-hydroxylase chr12 GO:0046394 Not Cancer Driver No 133 0.294 13 4 0.308 222
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0046394 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCBD1 PCBD1 P61457 Pterin-4-alpha-carbinolamine dehydratase chr10 GO:0046394 Not Cancer Driver No 8 0.077 7 0 0.0 3
PCBD2_ENST00000254908 PCBD2 Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 chr5 GO:0046394 Not Cancer Driver No 6 0.046 3 0 0.0 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0046394 Not Cancer Driver No 166 0.132 782 101 0.129 1
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 GO:0046394 Not Cancer Driver No 51 0.096 38 4 0.105 8
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0046394 Not Cancer Driver No 112 0.195 26 5 0.192 101
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0046394 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0046394 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0046394 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0046394 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0046394 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLOD2_ENST00000360060 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 GO:0046394 Not Cancer Driver No 109 0.148 17 3 0.176 4
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 GO:0046394 Not Cancer Driver No 108 0.146 65 8 0.123 1
PLP1 PLP1 P60201 Myelin proteolipid protein chrX GO:0046394 Not Cancer Driver No 49 0.177 5 1 0.2 72
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0046394 Not Cancer Driver No 94 0.12 140 18 0.129 0
PRG3 PRG3 Q9Y2Y8 Proteoglycan 3 chr11 GO:0046394 Not Cancer Driver No 40 0.178 60 12 0.2 0
PSAT1 PSAT1 Q9Y617 Phosphoserine aminotransferase chr9 GO:0046394 Not Cancer Driver No 54 0.146 3 1 0.333 3
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 GO:0046394 Not Cancer Driver No 44 0.196 21 6 0.286 3
PTGDS PTGDS P41222 Prostaglandin-H2 D-isomerase chr9 GO:0046394 Not Cancer Driver No 31 0.163 13 3 0.231 0
PTGES PTGES O14684 Prostaglandin E synthase chr9 GO:0046394 Not Cancer Driver No 10 0.066 0 0 0.0 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0046394 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0046394 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS1 PTGS1 P23219 Prostaglandin G/H synthase 1 chr9 GO:0046394 Not Cancer Driver No 123 0.205 28 3 0.107 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0046394 Not Cancer Driver No 105 0.174 30 5 0.167 0
PYCR1_ENST00000329875 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 GO:0046394 Not Cancer Driver No 31 0.097 67 10 0.149 9
PYCR2 PYCR2 Q96C36 Pyrroline-5-carboxylate reductase 2 chr1 GO:0046394 Not Cancer Driver No 31 0.097 41 3 0.073 2
PYCR3_ENST00000495276 PYCR3 Q53H96 Pyrroline-5-carboxylate reductase 3 chr8 GO:0046394 Not Cancer Driver No 21 0.077 11 0 0.0 0
QKI QKI Q96PU8 Protein quaking chr6 GO:0046394 Census, Compendium Yes 52 0.152 174 27 0.155 0
RBP1_ENST00000619087 RBP1 P09455 Retinol-binding protein 1 chr3 GO:0046394 Not Cancer Driver No 24 0.178 0 0 0.0 0
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0046394 Not Cancer Driver No 33 0.097 8 0 0.0 0
RGN RGN Q15493 Regucalcin chrX GO:0046394 Not Cancer Driver No 38 0.127 14 3 0.214 0
SCP2 SCP2 P22307 Sterol carrier protein 2 chr1 GO:0046394 Not Cancer Driver No 59 0.108 45 2 0.044 0
SDS SDS P20132 L-serine dehydratase/L-threonine deaminase chr12 GO:0046394 Not Cancer Driver No 40 0.122 17 1 0.059 0
SDSL SDSL Q96GA7 Serine dehydratase-like chr12 GO:0046394 Not Cancer Driver No 48 0.146 15 1 0.067 0
SEPHS1 SEPHS1 P49903 Selenide, water dikinase 1 chr10 GO:0046394 Not Cancer Driver No 58 0.148 29 10 0.345 0
SEPHS2 SEPHS2 Q99611 Selenide, water dikinase 2 chr16 GO:0046394 Not Cancer Driver No 48 0.107 104 2 0.019 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0046394 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERINC5_ENST00000509193 SERINC5 Q86VE9 Serine incorporator 5 chr5 GO:0046394 Not Cancer Driver No 38 0.09 13 1 0.077 0
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0046394 Not Cancer Driver No 51 0.106 32 7 0.219 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 GO:0046394 Not Cancer Driver No 57 0.113 58 5 0.086 1
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0046394 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0046394 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC27A2 SLC27A2 O14975 Very long-chain acyl-CoA synthetase chr15 GO:0046394 Not Cancer Driver No 95 0.153 4 0 0.0 0
SLC27A5 SLC27A5 Q9Y2P5 Bile acyl-CoA synthetase chr19 GO:0046394 Not Cancer Driver No 107 0.155 7 2 0.286 0
SRR SRR Q9GZT4 Serine racemase chr17 GO:0046394 Not Cancer Driver No 40 0.118 32 6 0.188 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0046394 Census Yes 96 0.151 131 27 0.206 5
TBXAS1_ENST00000448866 TBXAS1 P24557 Thromboxane-A synthase chr7 GO:0046394 Not Cancer Driver No 116 0.218 44 8 0.182 4
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 GO:0046394 Not Cancer Driver No 41 0.133 0 0 0.0 1
TECRL TECRL Q5HYJ1 Trans-2,3-enoyl-CoA reductase-like chr4 GO:0046394 Not Cancer Driver No 147 0.405 6 4 0.667 0
THNSL2 THNSL2 Q86YJ6 Threonine synthase-like 2 chr2 GO:0046394 Not Cancer Driver No 73 0.151 51 3 0.059 0
UGDH_ENST00000506179 UGDH O60701 UDP-glucose 6-dehydrogenase chr4 GO:0046394 Not Cancer Driver No 54 0.109 39 4 0.103 5
UPB1 UPB1 Q9UBR1 Beta-ureidopropionase chr22 GO:0046394 Not Cancer Driver No 66 0.172 22 7 0.318 8
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 GO:0046394 Not Cancer Driver No 34 0.128 7 0 0.0 21