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Total number of protein in "GO:0005524" GO term:  1445

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AACS AACS Q86V21 Acetoacetyl-CoA synthetase chr12 GO:0005524 Not Cancer Driver No 92 0.137 16 0 0.0 0
AAK1 AAK1 Q2M2I8 AP2-associated protein kinase 1 chr2 GO:0005524 Not Cancer Driver No 109 0.113 654 70 0.107 0
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0005524 Not Cancer Driver No 97 0.1 140 14 0.1 5
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 GO:0005524 Not Cancer Driver No 123 0.125 203 25 0.123 5
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 GO:0005524 Not Cancer Driver No 40 0.097 157 20 0.127 0
AASDH AASDH Q4L235 Beta-alanine-activating enzyme chr4 GO:0005524 Not Cancer Driver No 130 0.118 37 5 0.135 0
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 GO:0005524 Not Cancer Driver No 108 0.079 912 75 0.082 0
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0005524 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA10 ABCA10 Q8WWZ4 ATP-binding cassette sub-family A member 10 chr17 GO:0005524 Not Cancer Driver No 251 0.163 98 17 0.173 0
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0005524 Not Cancer Driver No 511 0.197 136 23 0.169 14
ABCA13 ABCA13 Q86UQ4 ATP-binding cassette sub-family A member 13 chr7 GO:0005524 Not Cancer Driver No 930 0.184 162 14 0.086 0
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0005524 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0005524 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABCA4 ABCA4 P78363 Retinal-specific phospholipid-transporting ATPase ABCA4 chr1 GO:0005524 Not Cancer Driver No 363 0.16 244 33 0.135 226
ABCA5 ABCA5 Q8WWZ7 Cholesterol transporter ABCA5 chr17 GO:0005524 Not Cancer Driver No 214 0.13 52 5 0.096 0
ABCA6 ABCA6 Q8N139 ATP-binding cassette sub-family A member 6 chr17 GO:0005524 Not Cancer Driver No 271 0.168 50 12 0.24 0
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0005524 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCA8 ABCA8 O94911 ABC-type organic anion transporter ABCA8 chr17 GO:0005524 Not Cancer Driver No 290 0.179 91 20 0.22 0
ABCA9 ABCA9 Q8IUA7 ATP-binding cassette sub-family A member 9 chr17 GO:0005524 Not Cancer Driver No 269 0.166 82 14 0.171 0
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0005524 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0005524 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCB1_ENST00000265724 ABCB1 P08183 ATP-dependent translocase ABCB1 chr7 GO:0005524 Compendium Yes 367 0.287 103 31 0.301 0
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0005524 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABCB5 ABCB5 Q2M3G0 ATP-binding cassette sub-family B member 5 chr7 GO:0005524 Not Cancer Driver No 370 0.294 106 35 0.33 0
ABCB6 ABCB6 Q9NP58 ATP-binding cassette sub-family B member 6 chr2 GO:0005524 Not Cancer Driver No 87 0.103 27 1 0.037 11
ABCB7_ENST00000373394 ABCB7 O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial chrX GO:0005524 Not Cancer Driver No 117 0.156 79 14 0.177 4
ABCB8 ABCB8 Q9NUT2 Mitochondrial potassium channel ATP-binding subunit chr7 GO:0005524 Not Cancer Driver No 117 0.159 55 5 0.091 0
ABCB9 ABCB9 Q9NP78 ABC-type oligopeptide transporter ABCB9 chr12 GO:0005524 Not Cancer Driver No 80 0.104 49 1 0.02 0
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0005524 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABCC10 ABCC10 Q5T3U5 ATP-binding cassette sub-family C member 10 chr6 GO:0005524 Not Cancer Driver No 192 0.129 105 9 0.086 0
ABCC11_ENST00000356608 ABCC11 Q96J66 ATP-binding cassette sub-family C member 11 chr16 GO:0005524 Not Cancer Driver No 257 0.186 91 15 0.165 0
ABCC12 ABCC12 Q96J65 ATP-binding cassette sub-family C member 12 chr16 GO:0005524 Not Cancer Driver No 247 0.182 116 16 0.138 0
ABCC2 ABCC2 Q92887 ATP-binding cassette sub-family C member 2 chr10 GO:0005524 Not Cancer Driver No 202 0.131 102 23 0.225 4
ABCC3 ABCC3 O15438 ATP-binding cassette sub-family C member 3 chr17 GO:0005524 Not Cancer Driver No 210 0.138 113 19 0.168 0
ABCC4_ENST00000376887 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 GO:0005524 Not Cancer Driver No 174 0.131 97 6 0.062 0
ABCC5 ABCC5 O15440 ATP-binding cassette sub-family C member 5 chr3 GO:0005524 Not Cancer Driver No 191 0.133 255 29 0.114 0
ABCC6 ABCC6 O95255 ATP-binding cassette sub-family C member 6 chr16 GO:0005524 Not Cancer Driver No 193 0.128 133 20 0.15 87
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0005524 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCC9_ENST00000261201 ABCC9 O60706 ATP-binding cassette sub-family C member 9 chr12 GO:0005524 Not Cancer Driver No 368 0.238 132 30 0.227 15
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0005524 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0005524 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 GO:0005524 Not Cancer Driver No 75 0.114 21 2 0.095 0
ABCD4 ABCD4 O14678 Lysosomal cobalamin transporter ABCD4 chr14 GO:0005524 Not Cancer Driver No 77 0.127 6 1 0.167 3
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 GO:0005524 Not Cancer Driver No 74 0.124 36 6 0.167 0
ABCF1 ABCF1 Q8NE71 ATP-binding cassette sub-family F member 1 chr6 GO:0005524 Not Cancer Driver No 106 0.125 445 64 0.144 0
ABCF2 ABCF2 Q9UG63 ATP-binding cassette sub-family F member 2 chr7 GO:0005524 Not Cancer Driver No 112 0.18 153 20 0.131 0
ABCF3 ABCF3 Q9NUQ8 ATP-binding cassette sub-family F member 3 chr3 GO:0005524 Not Cancer Driver No 109 0.154 136 19 0.14 0
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0005524 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABCG2 ABCG2 Q9UNQ0 Broad substrate specificity ATP-binding cassette transporter ABCG2 chr4 GO:0005524 Not Cancer Driver No 124 0.189 35 10 0.286 0
ABCG4 ABCG4 Q9H172 ATP-binding cassette sub-family G member 4 chr11 GO:0005524 Not Cancer Driver No 122 0.189 29 7 0.241 0
ABCG5_ENST00000405322 ABCG5 Q9H222 ATP-binding cassette sub-family G member 5 chr2 GO:0005524 Not Cancer Driver No 77 0.118 43 8 0.186 6
ABCG8 ABCG8 Q9H221 ATP-binding cassette sub-family G member 8 chr2 GO:0005524 Not Cancer Driver No 137 0.204 40 8 0.2 10
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0005524 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0005524 Census, Compendium Yes 171 0.145 641 70 0.109 0
AC011005.1 AC011005.1 A0A1B0GUL7 Protein kinase domain-containing protein chr7 GO:0005524 Not Cancer Driver No 14 0.035 127 6 0.047 0
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0005524 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 GO:0005524 Not Cancer Driver No 120 0.109 114 12 0.105 0
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 GO:0005524 Not Cancer Driver No 93 0.168 41 3 0.073 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0005524 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0005524 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACSF2_ENST00000300441 ACSF2 Q96CM8 Medium-chain acyl-CoA ligase ACSF2, mitochondrial chr17 GO:0005524 Not Cancer Driver No 73 0.119 55 10 0.182 0
ACSF3_ENST00000406948 ACSF3 Q4G176 Malonate--CoA ligase ACSF3, mitochondrial chr16 GO:0005524 Not Cancer Driver No 87 0.151 48 11 0.229 9
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0005524 Not Cancer Driver No 85 0.122 27 1 0.037 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0005524 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0005524 Not Cancer Driver No 97 0.136 77 12 0.156 1
ACSL5_ENST00000354655 ACSL5 Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 chr10 GO:0005524 Not Cancer Driver No 98 0.143 22 5 0.227 0
ACSL6_ENST00000379240 ACSL6 Q9UKU0 Long-chain-fatty-acid--CoA ligase 6 chr5 GO:0005524 Census Yes 120 0.172 34 3 0.088 0
ACSM1_ENST00000520010 ACSM1 Q08AH1 Acyl-coenzyme A synthetase ACSM1, mitochondrial chr16 GO:0005524 Not Cancer Driver No 134 0.232 64 16 0.25 0
ACSM2A_ENST00000219054 ACSM2A Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial chr16 GO:0005524 Not Cancer Driver No 200 0.347 48 24 0.5 0
ACSM2B ACSM2B Q68CK6 Acyl-coenzyme A synthetase ACSM2B, mitochondrial chr16 GO:0005524 Not Cancer Driver No 230 0.399 45 23 0.511 0
ACSM3 ACSM3 Q53FZ2 Acyl-coenzyme A synthetase ACSM3, mitochondrial chr16 GO:0005524 Not Cancer Driver No 95 0.162 79 8 0.101 0
ACSM4 ACSM4 P0C7M7 Acyl-coenzyme A synthetase ACSM4, mitochondrial chr12 GO:0005524 Not Cancer Driver No 128 0.221 20 9 0.45 0
ACSM5 ACSM5 Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial chr16 GO:0005524 Not Cancer Driver No 152 0.263 84 27 0.321 0
ACSM6_ENST00000394005 ACSM6 Q6P461 Acyl-coenzyme A synthetase ACSM6, mitochondrial chr10 GO:0005524 Not Cancer Driver No 56 0.117 0 0 0.0 0
ACSS1 ACSS1 Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial chr20 GO:0005524 Not Cancer Driver No 79 0.115 76 6 0.079 0
ACSS2_ENST00000360596 ACSS2 Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic chr20 GO:0005524 Not Cancer Driver No 62 0.088 111 6 0.054 0
ACSS3 ACSS3 Q9H6R3 Acyl-CoA synthetase short-chain family member 3, mitochondrial chr12 GO:0005524 Not Cancer Driver No 194 0.283 63 10 0.159 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 GO:0005524 Not Cancer Driver No 70 0.186 48 14 0.292 84
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 GO:0005524 Not Cancer Driver No 50 0.133 39 4 0.103 17
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 GO:0005524 Not Cancer Driver No 73 0.194 29 5 0.172 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0005524 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 GO:0005524 Not Cancer Driver No 114 0.302 48 19 0.396 11
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0005524 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACTG2_ENST00000345517 ACTG2 P63267 Actin, gamma-enteric smooth muscle chr2 GO:0005524 Not Cancer Driver No 80 0.213 39 8 0.205 21
ACTR1A ACTR1A P61163 Alpha-centractin chr10 GO:0005524 Not Cancer Driver No 47 0.125 14 0 0.0 0
ACTR1B ACTR1B P42025 Beta-centractin chr2 GO:0005524 Not Cancer Driver No 59 0.157 17 4 0.235 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0005524 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:0005524 Not Cancer Driver No 32 0.077 16 2 0.125 0
ACTR3B ACTR3B Q9P1U1 Actin-related protein 3B chr7 GO:0005524 Not Cancer Driver No 55 0.132 5 0 0.0 0
ACTR3C ACTR3C Q9C0K3 Actin-related protein 3C chr7 GO:0005524 Not Cancer Driver No 23 0.11 1 0 0.0 0
ACTR8 ACTR8 Q9H981 Actin-related protein 8 chr3 GO:0005524 Not Cancer Driver No 61 0.098 239 21 0.088 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0005524 Census Yes 114 0.226 0 0 0.0 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0005524 Not Cancer Driver No 90 0.183 3 1 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0005524 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0005524 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0005524 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0005524 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADCK1 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 GO:0005524 Not Cancer Driver No 82 0.155 6 3 0.5 0
ADCK2 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 GO:0005524 Not Cancer Driver No 62 0.099 9 1 0.111 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0005524 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0005524 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0005524 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0005524 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0005524 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0005524 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0005524 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0005524 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0005524 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 GO:0005524 Not Cancer Driver No 195 0.144 271 42 0.155 0
ADK ADK P55263 Adenosine kinase chr10 GO:0005524 Not Cancer Driver No 29 0.08 33 2 0.061 3
AFG1L AFG1L Q8WV93 AFG1-like ATPase chr6 GO:0005524 Not Cancer Driver No 52 0.108 13 2 0.154 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 GO:0005524 Not Cancer Driver No 72 0.09 162 10 0.062 22
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0005524 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGK AGK Q53H12 Acylglycerol kinase, mitochondrial chr7 GO:0005524 Not Cancer Driver No 71 0.168 77 6 0.078 0
AK1_ENST00000373176 AK1 P00568 Adenylate kinase isoenzyme 1 chr9 GO:0005524 Not Cancer Driver No 19 0.098 55 3 0.055 4
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 GO:0005524 Not Cancer Driver No 23 0.096 76 12 0.158 2
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 GO:0005524 Not Cancer Driver No 23 0.101 33 3 0.091 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 GO:0005524 Not Cancer Driver No 26 0.117 24 3 0.125 0
AK5 AK5 Q9Y6K8 Adenylate kinase isoenzyme 5 chr1 GO:0005524 Not Cancer Driver No 116 0.206 161 44 0.273 0
AK6 AK6 Q9Y3D8 Adenylate kinase isoenzyme 6 chr5 GO:0005524 Not Cancer Driver No 6 0.035 13 0 0.0 0
AK7 AK7 Q96M32 Adenylate kinase 7 chr14 GO:0005524 Not Cancer Driver No 126 0.174 181 42 0.232 1
AK8 AK8 Q96MA6 Adenylate kinase 8 chr9 GO:0005524 Not Cancer Driver No 74 0.154 53 8 0.151 0
AK9 AK9 Q5TCS8 Adenylate kinase 9 chr6 GO:0005524 Not Cancer Driver No 235 0.123 589 58 0.098 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0005524 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0005524 Census Yes 77 0.16 84 9 0.107 2
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 GO:0005524 Census, Compendium Yes 92 0.192 131 24 0.183 3
ALDH18A1 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 GO:0005524 Not Cancer Driver No 94 0.118 86 13 0.151 15
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0005524 Census, Compendium Yes 303 0.187 575 114 0.198 16
ALPK1_ENST00000177648 ALPK1 Q96QP1 Alpha-protein kinase 1 chr4 GO:0005524 Not Cancer Driver No 183 0.147 480 64 0.133 1
ALPK2 ALPK2 Q86TB3 Alpha-protein kinase 2 chr18 GO:0005524 Not Cancer Driver No 406 0.187 1553 306 0.197 0
ALPK3 ALPK3 Q96L96 Alpha-protein kinase 3 chr15 GO:0005524 Not Cancer Driver No 264 0.138 1436 176 0.123 0
AMHR2 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 GO:0005524 Not Cancer Driver No 77 0.134 117 7 0.06 8
ANKK1 ANKK1 Q8NFD2 Ankyrin repeat and protein kinase domain-containing protein 1 chr11 GO:0005524 Not Cancer Driver No 103 0.135 90 7 0.078 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0005524 Not Cancer Driver No 127 0.102 17 1 0.059 0
AQR AQR O60306 RNA helicase aquarius chr15 GO:0005524 Not Cancer Driver No 201 0.135 297 31 0.104 0
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX GO:0005524 Census, Compendium Yes 84 0.139 181 32 0.177 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0005524 Not Cancer Driver No 279 0.127 87 8 0.092 0
ASNA1 GET3 O43681 ATPase GET3 chr19 GO:0005524 Not Cancer Driver No 37 0.106 17 2 0.118 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0005524 Not Cancer Driver No 81 0.144 11 0 0.0 3
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0005524 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATAD1_ENST00000328142 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 GO:0005524 Not Cancer Driver No 32 0.089 71 3 0.042 0
ATAD2 ATAD2 Q6PL18 ATPase family AAA domain-containing protein 2 chr8 GO:0005524 Not Cancer Driver No 227 0.163 647 113 0.175 0
ATAD2B ATAD2B Q9ULI0 ATPase family AAA domain-containing protein 2B chr2 GO:0005524 Not Cancer Driver No 158 0.108 715 76 0.106 0
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 GO:0005524 Not Cancer Driver No 66 0.104 269 24 0.089 2
ATAD3B ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 GO:0005524 Not Cancer Driver No 84 0.13 243 19 0.078 0
ATAD3C ATAD3C Q5T2N8 ATPase family AAA domain-containing protein 3C chr1 GO:0005524 Not Cancer Driver No 48 0.117 43 9 0.209 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0005524 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0005524 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP10A ATP10A O60312 Phospholipid-transporting ATPase VA chr15 GO:0005524 Not Cancer Driver No 366 0.244 408 100 0.245 0
ATP10B ATP10B O94823 Phospholipid-transporting ATPase VB chr5 GO:0005524 Not Cancer Driver No 310 0.212 333 66 0.198 0
ATP10D ATP10D Q9P241 Phospholipid-transporting ATPase VD chr4 GO:0005524 Not Cancer Driver No 253 0.177 235 45 0.191 0
ATP11A ATP11A P98196 Phospholipid-transporting ATPase IH chr13 GO:0005524 Not Cancer Driver No 171 0.151 77 17 0.221 0
ATP11B ATP11B Q9Y2G3 Phospholipid-transporting ATPase IF chr3 GO:0005524 Not Cancer Driver No 129 0.11 73 10 0.137 0
ATP11C ATP11C Q8NB49 Phospholipid-transporting ATPase IG chrX GO:0005524 Not Cancer Driver No 198 0.175 32 5 0.156 1
ATP12A_ENST00000381946 ATP12A P54707 Potassium-transporting ATPase alpha chain 2 chr13 GO:0005524 Not Cancer Driver No 203 0.195 117 24 0.205 0
ATP13A1 ATP13A1 Q9HD20 Endoplasmic reticulum transmembrane helix translocase chr19 GO:0005524 Not Cancer Driver No 131 0.109 95 15 0.158 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0005524 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP13A3_ENST00000256031 ATP13A3 Q9H7F0 Polyamine-transporting ATPase 13A3 chr3 GO:0005524 Not Cancer Driver No 149 0.122 49 11 0.224 0
ATP13A4 ATP13A4 Q4VNC1 Probable cation-transporting ATPase 13A4 chr3 GO:0005524 Not Cancer Driver No 213 0.178 34 5 0.147 0
ATP13A5 ATP13A5 Q4VNC0 Probable cation-transporting ATPase 13A5 chr3 GO:0005524 Not Cancer Driver No 251 0.206 70 13 0.186 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0005524 Census Yes 115 0.112 115 16 0.139 6
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0005524 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0005524 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0005524 Not Cancer Driver No 195 0.19 117 24 0.205 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0005524 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0005524 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0005524 Not Cancer Driver No 130 0.13 147 16 0.109 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0005524 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0005524 Not Cancer Driver No 248 0.2 360 82 0.228 0
ATP2B3_ENST00000349466 ATP2B3 Q16720 Plasma membrane calcium-transporting ATPase 3 chrX GO:0005524 Census Yes 245 0.201 328 74 0.226 2
ATP2C1_ENST00000508532 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 GO:0005524 Not Cancer Driver No 125 0.136 44 5 0.114 20
ATP2C2_ENST00000262429 ATP2C2 O75185 Calcium-transporting ATPase type 2C member 2 chr16 GO:0005524 Not Cancer Driver No 123 0.13 54 6 0.111 0
ATP4A ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 GO:0005524 Not Cancer Driver No 201 0.194 121 30 0.248 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0005524 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0005524 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5F1D_ENST00000591660 ATP5F1D P30049 ATP synthase subunit delta, mitochondrial chr19 GO:0005524 Not Cancer Driver No 7 0.042 5 1 0.2 2
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX GO:0005524 Not Cancer Driver No 67 0.143 0 0 0.0 4
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 GO:0005524 Not Cancer Driver No 86 0.139 31 2 0.065 4
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 GO:0005524 Not Cancer Driver No 77 0.15 66 14 0.212 9
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 GO:0005524 Not Cancer Driver No 63 0.123 49 4 0.082 1
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0005524 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATP7B ATP7B P35670 Copper-transporting ATPase 2 chr13 GO:0005524 Not Cancer Driver No 205 0.14 257 45 0.175 184
ATP8A1 ATP8A1 Q9Y2Q0 Phospholipid-transporting ATPase IA chr4 GO:0005524 Not Cancer Driver No 185 0.159 84 7 0.083 0
ATP8A2 ATP8A2 Q9NTI2 Phospholipid-transporting ATPase IB chr13 GO:0005524 Not Cancer Driver No 236 0.199 78 14 0.179 1
ATP8B1 ATP8B1 O43520 Phospholipid-transporting ATPase IC chr18 GO:0005524 Not Cancer Driver No 156 0.125 133 17 0.128 29
ATP8B2 ATP8B2 P98198 Phospholipid-transporting ATPase ID chr1 GO:0005524 Not Cancer Driver No 182 0.151 101 11 0.109 0
ATP8B3 ATP8B3 O60423 Phospholipid-transporting ATPase IK chr19 GO:0005524 Not Cancer Driver No 151 0.116 180 22 0.122 0
ATP8B4_ENST00000559829 ATP8B4 Q8TF62 Probable phospholipid-transporting ATPase IM chr15 GO:0005524 Not Cancer Driver No 242 0.203 102 27 0.265 0
ATP9A ATP9A O75110 Probable phospholipid-transporting ATPase IIA chr20 GO:0005524 Not Cancer Driver No 175 0.167 69 18 0.261 0
ATP9B ATP9B O43861 Probable phospholipid-transporting ATPase IIB chr18 GO:0005524 Not Cancer Driver No 145 0.126 111 9 0.081 0
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0005524 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0005524 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0005524 Not Cancer Driver No 36 0.089 178 21 0.118 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0005524 Not Cancer Driver No 51 0.148 63 8 0.127 0
AURKC AURKC Q9UQB9 Aurora kinase C chr19 GO:0005524 Not Cancer Driver No 70 0.227 43 5 0.116 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0005524 Not Cancer Driver No 168 0.188 341 64 0.188 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0005524 Not Cancer Driver No 153 0.103 840 87 0.104 0
BBS10 BBS10 Q8TAM1 Bardet-Biedl syndrome 10 protein chr12 GO:0005524 Not Cancer Driver No 78 0.108 67 11 0.164 24
BBS12 BBS12 Q6ZW61 Bardet-Biedl syndrome 12 protein chr4 GO:0005524 Not Cancer Driver No 88 0.124 34 5 0.147 10
BCKDK BCKDK O14874 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial chr16 GO:0005524 Not Cancer Driver No 62 0.15 39 3 0.077 3
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0005524 Census, Compendium Yes 146 0.115 603 69 0.114 0
BCS1L BCS1L Q9Y276 Mitochondrial chaperone BCS1 chr2 GO:0005524 Not Cancer Driver No 35 0.084 5 0 0.0 21
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0005524 Not Cancer Driver No 94 0.186 75 21 0.28 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0005524 Census Yes 153 0.108 667 70 0.105 8
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 GO:0005524 Not Cancer Driver No 124 0.107 827 89 0.108 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0005524 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0005524 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0005524 Compendium Yes 141 0.136 601 70 0.116 19
BMS1 BMS1 Q14692 Ribosome biogenesis protein BMS1 homolog chr10 GO:0005524 Not Cancer Driver No 179 0.14 708 88 0.124 1
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0005524 Not Cancer Driver No 106 0.157 172 27 0.157 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0005524 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0005524 Census Yes 174 0.139 397 59 0.149 6
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0005524 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0005524 Not Cancer Driver No 90 0.122 321 39 0.121 0
BTAF1 BTAF1 O14981 TATA-binding protein-associated factor 172 chr10 GO:0005524 Not Cancer Driver No 215 0.116 360 52 0.144 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0005524 Census, Compendium Yes 147 0.223 114 27 0.237 110
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 GO:0005524 Not Cancer Driver No 139 0.128 466 64 0.137 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 GO:0005524 Census Yes 96 0.091 480 35 0.073 7
CACNA1B CACNA1B Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B chr9 GO:0005524 Not Cancer Driver No 416 0.178 917 115 0.125 0
CAD CAD P27708 CAD protein chr2 GO:0005524 Not Cancer Driver No 287 0.129 368 52 0.141 1
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0005524 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0005524 Not Cancer Driver No 90 0.234 42 14 0.333 0
CAMK1G_ENST00000361322 CAMK1G Q96NX5 Calcium/calmodulin-dependent protein kinase type 1G chr1 GO:0005524 Not Cancer Driver No 62 0.13 91 16 0.176 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0005524 Not Cancer Driver No 83 0.174 62 10 0.161 7
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 GO:0005524 Not Cancer Driver No 86 0.129 273 28 0.103 6
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0005524 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAMK2G_ENST00000423381 CAMK2G Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma chr10 GO:0005524 Not Cancer Driver No 68 0.122 145 14 0.097 1
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0005524 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAMKK1_ENST00000348335 CAMKK1 Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 chr17 GO:0005524 Not Cancer Driver No 82 0.162 246 32 0.13 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0005524 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAMKV CAMKV Q8NCB2 CaM kinase-like vesicle-associated protein chr3 GO:0005524 Not Cancer Driver No 87 0.174 226 30 0.133 0
CARNS1_ENST00000307823 CARNS1 A5YM72 Carnosine synthase 1 chr11 GO:0005524 Not Cancer Driver No 74 0.089 42 4 0.095 0
CARS2 CARS2 Q9HA77 Probable cysteine--tRNA ligase, mitochondrial chr13 GO:0005524 Not Cancer Driver No 51 0.09 87 8 0.092 1
CARS_ENST00000397111 CARS1 P49589 Cysteine--tRNA ligase, cytoplasmic chr11 GO:0005524 Not Cancer Driver No 97 0.13 184 35 0.19 3
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0005524 Not Cancer Driver No 118 0.127 285 45 0.158 4
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 GO:0005524 Not Cancer Driver No 27 0.068 62 8 0.129 0
CBWD2 CBWD2 Q8IUF1 COBW domain-containing protein 2 chr2 GO:0005524 Not Cancer Driver No 20 0.051 54 6 0.111 0
CBWD3 CBWD3 Q5JTY5 COBW domain-containing protein 3 chr9 GO:0005524 Not Cancer Driver No 16 0.041 62 1 0.016 0
CBWD5 CBWD5 Q5RIA9 COBW domain-containing protein 5 chr9 GO:0005524 Not Cancer Driver No 11 0.028 62 8 0.129 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0005524 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0005524 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0005524 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0005524 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0005524 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 GO:0005524 Not Cancer Driver No 90 0.17 1 0 0.0 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0005524 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0005524 Not Cancer Driver No 41 0.075 36 2 0.056 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 GO:0005524 Not Cancer Driver No 216 0.388 104 46 0.442 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0005524 Not Cancer Driver No 26 0.11 95 11 0.116 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 GO:0005524 Not Cancer Driver No 215 0.124 717 80 0.112 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 GO:0005524 Not Cancer Driver No 185 0.108 696 92 0.132 0
CDC42BPG CDC42BPG Q6DT37 Serine/threonine-protein kinase MRCK gamma chr11 GO:0005524 Not Cancer Driver No 166 0.107 736 79 0.107 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0005524 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:0005524 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0005524 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK10 CDK10 Q15131 Cyclin-dependent kinase 10 chr16 GO:0005524 Not Cancer Driver No 42 0.117 30 4 0.133 0
CDK11A CDK11A Q9UQ88 Cyclin-dependent kinase 11A chr1 GO:0005524 Not Cancer Driver No 66 0.084 485 44 0.091 0
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 GO:0005524 Not Cancer Driver No 74 0.093 501 35 0.07 0
CDK12 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 GO:0005524 Census, Compendium Yes 225 0.151 1202 160 0.133 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 GO:0005524 Not Cancer Driver No 155 0.103 1138 99 0.087 6
CDK14 CDK14 O94921 Cyclin-dependent kinase 14 chr7 GO:0005524 Not Cancer Driver No 93 0.198 154 21 0.136 0
CDK15 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 GO:0005524 Not Cancer Driver No 66 0.152 35 4 0.114 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:0005524 Not Cancer Driver No 55 0.111 139 30 0.216 0
CDK17 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 GO:0005524 Not Cancer Driver No 76 0.145 198 26 0.131 0
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 GO:0005524 Not Cancer Driver No 64 0.135 132 17 0.129 0
CDK19 CDK19 Q9BWU1 Cyclin-dependent kinase 19 chr6 GO:0005524 Not Cancer Driver No 63 0.125 191 28 0.147 8
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0005524 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 GO:0005524 Not Cancer Driver No 36 0.104 32 1 0.031 0
CDK3_ENST00000448471 CDK3 Q00526 Cyclin-dependent kinase 3 chr17 GO:0005524 Not Cancer Driver No 40 0.131 17 2 0.118 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0005524 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0005524 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0005524 Census Yes 40 0.123 24 3 0.125 1
CDK7 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:0005524 Not Cancer Driver No 41 0.118 38 5 0.132 0
CDK8 CDK8 P49336 Cyclin-dependent kinase 8 chr13 GO:0005524 Not Cancer Driver No 76 0.164 152 18 0.118 7
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0005524 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKL1 CDKL1 Q00532 Cyclin-dependent kinase-like 1 chr14 GO:0005524 Not Cancer Driver No 28 0.078 21 0 0.0 0
CDKL2_ENST00000429927 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 GO:0005524 Not Cancer Driver No 63 0.128 171 21 0.123 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0005524 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL4_ENST00000395035 CDKL4 Q5MAI5 Cyclin-dependent kinase-like 4 chr2 GO:0005524 Not Cancer Driver No 58 0.153 52 9 0.173 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0005524 Not Cancer Driver No 165 0.172 685 120 0.175 18
CENPE CENPE Q02224 Centromere-associated protein E chr4 GO:0005524 Not Cancer Driver No 343 0.127 1620 228 0.141 2
CERK CERK Q8TCT0 Ceramide kinase chr22 GO:0005524 Not Cancer Driver No 56 0.104 48 5 0.104 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0005524 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0005524 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHD1 CHD1 O14646 Chromodomain-helicase-DNA-binding protein 1 chr5 GO:0005524 Not Cancer Driver No 172 0.101 975 109 0.112 4
CHD1L CHD1L Q86WJ1 Chromodomain-helicase-DNA-binding protein 1-like chr1 GO:0005524 Not Cancer Driver No 98 0.109 225 30 0.133 0
CHD2 CHD2 O14647 Chromodomain-helicase-DNA-binding protein 2 chr15 GO:0005524 Census, Compendium Yes 222 0.121 1051 136 0.129 2
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 GO:0005524 Not Cancer Driver No 235 0.117 1015 122 0.12 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 GO:0005524 Census, Compendium Yes 419 0.219 974 177 0.182 6
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:0005524 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0005524 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0005524 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0005524 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHD9_ENST00000398510 CHD9 Q3L8U1 Chromodomain-helicase-DNA-binding protein 9 chr16 GO:0005524 Not Cancer Driver No 301 0.104 1653 162 0.098 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0005524 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0005524 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHKA CHKA P35790 Choline kinase alpha chr11 GO:0005524 Not Cancer Driver No 45 0.098 119 4 0.034 0
CHKB CHKB Q9Y259 Choline/ethanolamine kinase chr22 GO:0005524 Not Cancer Driver No 42 0.106 37 3 0.081 2
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 GO:0005524 Not Cancer Driver No 47 0.142 119 17 0.143 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0005524 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0005524 Not Cancer Driver No 74 0.099 116 9 0.078 0
CIITA_ENST00000324288 CIITA P33076 MHC class II transactivator chr16 GO:0005524 Census, Compendium Yes 195 0.173 318 53 0.167 2
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:0005524 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CKB CKB P12277 Creatine kinase B-type chr14 GO:0005524 Not Cancer Driver No 31 0.081 102 4 0.039 0
CKM CKM P06732 Creatine kinase M-type chr19 GO:0005524 Not Cancer Driver No 58 0.152 118 19 0.161 0
CKMT1B_ENST00000441322 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 GO:0005524 Not Cancer Driver No 25 0.06 77 1 0.013 0
CKMT2_ENST00000437669 CKMT2 P17540 Creatine kinase S-type, mitochondrial chr5 GO:0005524 Not Cancer Driver No 70 0.167 68 12 0.176 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0005524 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLCN4 CLCN4 P51793 H(+)/Cl(-) exchange transporter 4 chrX GO:0005524 Not Cancer Driver No 118 0.155 62 13 0.21 11
CLCN5 CLCN5 P51795 H(+)/Cl(-) exchange transporter 5 chrX GO:0005524 Not Cancer Driver No 138 0.169 81 6 0.074 32
CLCN6 CLCN6 P51797 H(+)/Cl(-) exchange transporter 6 chr1 GO:0005524 Not Cancer Driver No 123 0.142 109 24 0.22 1
CLCN7 CLCN7 P51798 H(+)/Cl(-) exchange transporter 7 chr16 GO:0005524 Not Cancer Driver No 102 0.127 94 7 0.074 29
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 GO:0005524 Not Cancer Driver No 64 0.132 131 21 0.16 0
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 GO:0005524 Not Cancer Driver No 104 0.208 151 37 0.245 0
CLK3 CLK3 P49761 Dual specificity protein kinase CLK3 chr15 GO:0005524 Not Cancer Driver No 67 0.105 295 27 0.092 0
CLK4 CLK4 Q9HAZ1 Dual specificity protein kinase CLK4 chr5 GO:0005524 Not Cancer Driver No 60 0.125 102 14 0.137 0
CLP1 CLP1 Q92989 Polyribonucleotide 5'-hydroxyl-kinase Clp1 chr11 GO:0005524 Census Yes 59 0.139 58 12 0.207 1
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 GO:0005524 Not Cancer Driver No 69 0.098 224 25 0.112 11
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 GO:0005524 Not Cancer Driver No 66 0.104 195 22 0.113 1
CMPK2 CMPK2 Q5EBM0 UMP-CMP kinase 2, mitochondrial chr2 GO:0005524 Not Cancer Driver No 41 0.091 99 8 0.081 0
CNNM2 CNNM2 Q9H8M5 Metal transporter CNNM2 chr10 GO:0005524 Not Cancer Driver No 116 0.133 195 22 0.113 5
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 GO:0005524 Not Cancer Driver No 57 0.101 50 4 0.08 1
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 GO:0005524 Not Cancer Driver No 95 0.147 166 29 0.175 12
COQ8B COQ8B Q96D53 Atypical kinase COQ8B, mitochondrial chr19 GO:0005524 Not Cancer Driver No 53 0.097 117 15 0.128 8
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0005524 Not Cancer Driver No 368 0.245 73 22 0.301 140
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0005524 Census Yes 133 0.137 124 17 0.137 20
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0005524 Not Cancer Driver No 41 0.091 18 1 0.056 0
CSNK1A1L CSNK1A1L Q8N752 Casein kinase I isoform alpha-like chr13 GO:0005524 Not Cancer Driver No 75 0.223 46 7 0.152 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 GO:0005524 Not Cancer Driver No 44 0.131 46 3 0.065 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0005524 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0005524 Not Cancer Driver No 62 0.149 133 18 0.135 0
CSNK1G1 CSNK1G1 Q9HCP0 Casein kinase I isoform gamma-1 chr15 GO:0005524 Not Cancer Driver No 52 0.123 130 15 0.115 0
CSNK1G2 CSNK1G2 P78368 Casein kinase I isoform gamma-2 chr19 GO:0005524 Not Cancer Driver No 43 0.104 111 13 0.117 0
CSNK1G3_ENST00000361991 CSNK1G3 Q9Y6M4 Casein kinase I isoform gamma-3 chr5 GO:0005524 Not Cancer Driver No 61 0.136 151 22 0.146 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0005524 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0005524 Not Cancer Driver No 43 0.123 13 1 0.077 0
CSNK2A3 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 GO:0005524 Not Cancer Driver No 66 0.169 75 10 0.133 0
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 GO:0005524 Not Cancer Driver No 70 0.118 83 10 0.12 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX GO:0005524 Not Cancer Driver No 57 0.097 65 9 0.138 0
CUL9 CUL9 Q8IWT3 Cullin-9 chr6 GO:0005524 Not Cancer Driver No 321 0.128 633 73 0.115 0
DALRD3 DALRD3 Q5D0E6 DALR anticodon-binding domain-containing protein 3 chr3 GO:0005524 Not Cancer Driver No 49 0.09 40 4 0.1 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0005524 Not Cancer Driver No 193 0.135 114 11 0.096 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0005524 Not Cancer Driver No 55 0.149 53 9 0.17 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0005524 Not Cancer Driver No 56 0.123 82 7 0.085 0
DARS DARS1 P14868 Aspartate--tRNA ligase, cytoplasmic chr2 GO:0005524 Not Cancer Driver No 55 0.11 110 21 0.191 8
DARS2 DARS2 Q6PI48 Aspartate--tRNA ligase, mitochondrial chr1 GO:0005524 Not Cancer Driver No 63 0.098 91 11 0.121 11
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 GO:0005524 Not Cancer Driver No 128 0.085 495 44 0.089 0
DCAKD DCAKD Q8WVC6 Dephospho-CoA kinase domain-containing protein chr17 GO:0005524 Not Cancer Driver No 31 0.134 2 0 0.0 0
DCK DCK P27707 Deoxycytidine kinase chr4 GO:0005524 Not Cancer Driver No 29 0.112 22 4 0.182 0
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 GO:0005524 Not Cancer Driver No 209 0.282 252 77 0.306 0
DCLK2_ENST00000296550 DCLK2 Q8N568 Serine/threonine-protein kinase DCLK2 chr4 GO:0005524 Not Cancer Driver No 105 0.137 260 23 0.088 0
DCLK3 DCLK3 Q9C098 Serine/threonine-protein kinase DCLK3 chr3 GO:0005524 Not Cancer Driver No 136 0.21 395 87 0.22 0
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 GO:0005524 Not Cancer Driver No 123 0.135 253 49 0.194 0
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0005524 Census Yes 192 0.225 118 34 0.288 7
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0005524 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX10 DDX10 Q13206 Probable ATP-dependent RNA helicase DDX10 chr11 GO:0005524 Census Yes 93 0.106 400 46 0.115 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0005524 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0005524 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX18 DDX18 Q9NVP1 ATP-dependent RNA helicase DDX18 chr2 GO:0005524 Not Cancer Driver No 111 0.166 239 36 0.151 0
DDX19A DDX19A Q9NUU7 ATP-dependent RNA helicase DDX19A chr16 GO:0005524 Not Cancer Driver No 37 0.077 112 11 0.098 0
DDX19B DDX19B Q9UMR2 ATP-dependent RNA helicase DDX19B chr16 GO:0005524 Not Cancer Driver No 44 0.092 113 9 0.08 0
DDX20 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 GO:0005524 Not Cancer Driver No 89 0.108 299 33 0.11 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0005524 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 GO:0005524 Not Cancer Driver No 121 0.148 426 71 0.167 0
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 GO:0005524 Not Cancer Driver No 86 0.1 452 40 0.088 0
DDX25 DDX25 Q9UHL0 ATP-dependent RNA helicase DDX25 chr11 GO:0005524 Not Cancer Driver No 54 0.112 39 4 0.103 0
DDX27 DDX27 Q96GQ7 Probable ATP-dependent RNA helicase DDX27 chr20 GO:0005524 Not Cancer Driver No 101 0.127 383 50 0.131 0
DDX28 DDX28 Q9NUL7 Probable ATP-dependent RNA helicase DDX28 chr16 GO:0005524 Not Cancer Driver No 37 0.069 127 3 0.024 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 GO:0005524 Not Cancer Driver No 99 0.116 342 38 0.111 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 GO:0005524 Not Cancer Driver No 44 0.103 37 2 0.054 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:0005524 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0005524 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX3Y_ENST00000336079 DDX3Y O15523 ATP-dependent RNA helicase DDX3Y chrY GO:0005524 Not Cancer Driver No 31 0.047 289 18 0.062 0
DDX4 DDX4 Q9NQI0 Probable ATP-dependent RNA helicase DDX4 chr5 GO:0005524 Not Cancer Driver No 115 0.159 315 49 0.156 0
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 GO:0005524 Not Cancer Driver No 82 0.132 180 26 0.144 1
DDX42 DDX42 Q86XP3 ATP-dependent RNA helicase DDX42 chr17 GO:0005524 Not Cancer Driver No 126 0.134 607 79 0.13 0
DDX43 DDX43 Q9NXZ2 Probable ATP-dependent RNA helicase DDX43 chr6 GO:0005524 Not Cancer Driver No 103 0.159 231 46 0.199 0
DDX46_ENST00000354283 DDX46 Q7L014 Probable ATP-dependent RNA helicase DDX46 chr5 GO:0005524 Not Cancer Driver No 120 0.116 510 72 0.141 0
DDX47 DDX47 Q9H0S4 Probable ATP-dependent RNA helicase DDX47 chr12 GO:0005524 Not Cancer Driver No 51 0.112 98 7 0.071 0
DDX49 DDX49 Q9Y6V7 Probable ATP-dependent RNA helicase DDX49 chr19 GO:0005524 Not Cancer Driver No 55 0.114 78 6 0.077 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0005524 Census Yes 74 0.121 225 23 0.102 0
DDX50 DDX50 Q9BQ39 ATP-dependent RNA helicase DDX50 chr10 GO:0005524 Not Cancer Driver No 86 0.117 274 30 0.109 0
DDX51 DDX51 Q8N8A6 ATP-dependent RNA helicase DDX51 chr12 GO:0005524 Not Cancer Driver No 51 0.077 244 8 0.033 0
DDX53 DDX53 Q86TM3 Probable ATP-dependent RNA helicase DDX53 chrX GO:0005524 Not Cancer Driver No 113 0.179 199 42 0.211 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 GO:0005524 Not Cancer Driver No 113 0.128 458 52 0.114 0
DDX55 DDX55 Q8NHQ9 ATP-dependent RNA helicase DDX55 chr12 GO:0005524 Not Cancer Driver No 51 0.085 130 6 0.046 0
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 GO:0005524 Not Cancer Driver No 50 0.091 107 13 0.121 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0005524 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX59 DDX59 Q5T1V6 Probable ATP-dependent RNA helicase DDX59 chr1 GO:0005524 Not Cancer Driver No 83 0.134 174 26 0.149 2
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 GO:0005524 Census, Compendium Yes 44 0.091 129 7 0.054 5
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0005524 Not Cancer Driver No 224 0.131 131 12 0.092 0
DDX60L DDX60L Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like chr4 GO:0005524 Not Cancer Driver No 219 0.128 84 10 0.119 0
DGKA DGKA P23743 Diacylglycerol kinase alpha chr12 GO:0005524 Not Cancer Driver No 87 0.118 76 14 0.184 0
DGKB DGKB Q9Y6T7 Diacylglycerol kinase beta chr7 GO:0005524 Not Cancer Driver No 227 0.282 163 66 0.405 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0005524 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKE DGKE P52429 Diacylglycerol kinase epsilon chr17 GO:0005524 Not Cancer Driver No 84 0.148 34 3 0.088 2
DGKG DGKG P49619 Diacylglycerol kinase gamma chr3 GO:0005524 Not Cancer Driver No 160 0.202 182 43 0.236 0
DGKH DGKH Q86XP1 Diacylglycerol kinase eta chr13 GO:0005524 Not Cancer Driver No 138 0.113 326 43 0.132 0
DGKI DGKI O75912 Diacylglycerol kinase iota chr7 GO:0005524 Not Cancer Driver No 243 0.228 355 62 0.175 0
DGKK DGKK Q5KSL6 Diacylglycerol kinase kappa chrX GO:0005524 Not Cancer Driver No 262 0.206 382 90 0.236 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0005524 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0005524 Not Cancer Driver No 87 0.094 410 42 0.102 0
DGUOK DGUOK Q16854 Deoxyguanosine kinase, mitochondrial chr2 GO:0005524 Not Cancer Driver No 25 0.09 17 1 0.059 6
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 GO:0005524 Not Cancer Driver No 110 0.138 180 30 0.167 0
DHX16 DHX16 O60231 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 chr6 GO:0005524 Not Cancer Driver No 128 0.123 391 59 0.151 1
DHX29 DHX29 Q7Z478 ATP-dependent RNA helicase DHX29 chr5 GO:0005524 Not Cancer Driver No 146 0.107 405 34 0.084 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 GO:0005524 Not Cancer Driver No 165 0.138 260 40 0.154 6
DHX32 DHX32 Q7L7V1 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 chr10 GO:0005524 Not Cancer Driver No 88 0.118 60 8 0.133 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0005524 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX34 DHX34 Q14147 Probable ATP-dependent RNA helicase DHX34 chr19 GO:0005524 Not Cancer Driver No 175 0.153 326 41 0.126 0
DHX35 DHX35 Q9H5Z1 Probable ATP-dependent RNA helicase DHX35 chr20 GO:0005524 Not Cancer Driver No 91 0.129 47 6 0.128 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0005524 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX37 DHX37 Q8IY37 Probable ATP-dependent RNA helicase DHX37 chr12 GO:0005524 Not Cancer Driver No 165 0.143 433 66 0.152 5
DHX38 DHX38 Q92620 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 chr16 GO:0005524 Not Cancer Driver No 139 0.113 622 83 0.133 1
DHX40 DHX40 Q8IX18 Probable ATP-dependent RNA helicase DHX40 chr17 GO:0005524 Not Cancer Driver No 90 0.116 166 24 0.145 0
DHX57 DHX57 Q6P158 Putative ATP-dependent RNA helicase DHX57 chr2 GO:0005524 Not Cancer Driver No 147 0.106 294 32 0.109 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0005524 Not Cancer Driver No 62 0.091 84 8 0.095 0
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 GO:0005524 Not Cancer Driver No 138 0.113 490 72 0.147 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0005524 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0005524 Census, Compendium Yes 264 0.137 362 45 0.124 4
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0005524 Not Cancer Driver No 39 0.115 49 5 0.102 0
DMPK_ENST00000291270 DMPK Q09013 Myotonin-protein kinase chr19 GO:0005524 Not Cancer Driver No 54 0.086 220 14 0.064 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0005524 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNAH1 DNAH1 Q9P2D7 Dynein axonemal heavy chain 1 chr3 GO:0005524 Not Cancer Driver No 499 0.117 439 50 0.114 3
DNAH10 DNAH10 Q8IVF4 Dynein axonemal heavy chain 10 chr12 GO:0005524 Not Cancer Driver No 802 0.179 220 31 0.141 0
DNAH11 DNAH11 Q96DT5 Dynein axonemal heavy chain 11 chr7 GO:0005524 Not Cancer Driver No 885 0.196 221 36 0.163 3
DNAH12_ENST00000351747 DNAH12 Q6ZR08 Dynein axonemal heavy chain 12 chr3 GO:0005524 Not Cancer Driver No 243 0.079 174 22 0.126 0
DNAH14_ENST00000445597 DNAH14 Q0VDD8 Dynein axonemal heavy chain 14 chr1 GO:0005524 Not Cancer Driver No 176 0.05 358 24 0.067 0
DNAH17 DNAH17 Q9UFH2 Dynein axonemal heavy chain 17 chr17 GO:0005524 Not Cancer Driver No 725 0.162 175 31 0.177 3
DNAH2_ENST00000389173 DNAH2 Q9P225 Dynein axonemal heavy chain 2 chr17 GO:0005524 Not Cancer Driver No 663 0.15 246 42 0.171 1
DNAH3 DNAH3 Q8TD57 Dynein axonemal heavy chain 3 chr16 GO:0005524 Not Cancer Driver No 831 0.202 374 74 0.198 0
DNAH5 DNAH5 Q8TE73 Dynein axonemal heavy chain 5 chr5 GO:0005524 Not Cancer Driver No 1431 0.309 296 111 0.375 12
DNAH6 DNAH6 Q9C0G6 Dynein axonemal heavy chain 6 chr2 GO:0005524 Not Cancer Driver No 320 0.077 292 26 0.089 0
DNAH7 DNAH7 Q8WXX0 Dynein axonemal heavy chain 7 chr2 GO:0005524 Not Cancer Driver No 950 0.236 288 65 0.226 0
DNAH8_ENST00000359357 DNAH8 Q96JB1 Dynein axonemal heavy chain 8 chr6 GO:0005524 Not Cancer Driver No 975 0.217 209 54 0.258 0
DNAH9 DNAH9 Q9NYC9 Dynein axonemal heavy chain 9 chr17 GO:0005524 Not Cancer Driver No 1009 0.225 325 64 0.197 4
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0005524 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 GO:0005524 Not Cancer Driver No 50 0.121 174 27 0.155 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0005524 Not Cancer Driver No 50 0.104 152 21 0.138 0
DNAJA4_ENST00000394852 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 GO:0005524 Not Cancer Driver No 43 0.108 110 6 0.055 0
DNHD1 DNHD1 Q96M86 Dynein heavy chain domain-containing protein 1 chr11 GO:0005524 Not Cancer Driver No 333 0.07 700 36 0.051 0
DPH6 DPH6 Q7L8W6 Diphthine--ammonia ligase chr15 GO:0005524 Not Cancer Driver No 29 0.109 0 0 0.0 0
DQX1_ENST00000393951 DQX1 Q8TE96 ATP-dependent RNA helicase DQX1 chr2 GO:0005524 Not Cancer Driver No 92 0.128 88 14 0.159 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0005524 Not Cancer Driver No 112 0.121 112 4 0.036 2
DTYMK DTYMK P23919 Thymidylate kinase chr2 GO:0005524 Not Cancer Driver No 10 0.047 0 0 0.0 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 GO:0005524 Not Cancer Driver No 505 0.109 495 62 0.125 21
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 GO:0005524 Not Cancer Driver No 46 0.088 208 20 0.096 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 GO:0005524 Not Cancer Driver No 43 0.087 211 14 0.066 0
DYNC2H1_ENST00000375735 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0005524 Not Cancer Driver No 510 0.118 282 15 0.053 34
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0005524 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK1B_ENST00000323039 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 GO:0005524 Not Cancer Driver No 77 0.122 319 38 0.119 2
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0005524 Not Cancer Driver No 77 0.128 294 39 0.133 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0005524 Not Cancer Driver No 87 0.148 193 20 0.104 0
DYRK4_ENST00000010132 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 GO:0005524 Not Cancer Driver No 111 0.213 178 33 0.185 0
EARS2_ENST00000449606 EARS2 Q5JPH6 Probable glutamate--tRNA ligase, mitochondrial chr16 GO:0005524 Not Cancer Driver No 56 0.107 99 14 0.141 14
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0005524 Not Cancer Driver No 104 0.143 311 39 0.125 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0005524 Census, Compendium Yes 444 0.367 223 35 0.157 1
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0005524 Not Cancer Driver No 72 0.135 90 12 0.133 0
EHD2 EHD2 Q9NZN4 EH domain-containing protein 2 chr19 GO:0005524 Compendium Yes 85 0.157 125 12 0.096 0
EHD3 EHD3 Q9NZN3 EH domain-containing protein 3 chr2 GO:0005524 Not Cancer Driver No 104 0.194 77 18 0.234 0
EHD4 EHD4 Q9H223 EH domain-containing protein 4 chr15 GO:0005524 Not Cancer Driver No 54 0.1 98 7 0.071 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0005524 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0005524 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0005524 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0005524 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0005524 Not Cancer Driver No 40 0.114 83 11 0.133 9
EIF4A1 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 GO:0005524 Not Cancer Driver No 48 0.118 35 7 0.2 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:0005524 Census Yes 77 0.189 27 14 0.519 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0005524 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0005524 Not Cancer Driver No 229 0.143 1079 153 0.142 2
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0005524 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENTPD1_ENST00000371205 ENTPD1 P49961 Ectonucleoside triphosphate diphosphohydrolase 1 chr10 GO:0005524 Not Cancer Driver No 63 0.124 16 2 0.125 1
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 GO:0005524 Not Cancer Driver No 36 0.073 32 0 0.0 0
ENTPD3 ENTPD3 O75355 Ectonucleoside triphosphate diphosphohydrolase 3 chr3 GO:0005524 Not Cancer Driver No 64 0.121 14 2 0.143 0
ENTPD8 ENTPD8 Q5MY95 Ectonucleoside triphosphate diphosphohydrolase 8 chr9 GO:0005524 Not Cancer Driver No 46 0.093 5 0 0.0 0
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0005524 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPB42_ENST00000441366 EPB42 P16452 Protein 4.2 chr15 GO:0005524 Not Cancer Driver No 94 0.136 113 10 0.088 4
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0005524 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA10 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 GO:0005524 Not Cancer Driver No 171 0.17 225 41 0.182 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0005524 Compendium Yes 171 0.175 187 39 0.209 3
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0005524 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0005524 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:0005524 Not Cancer Driver No 341 0.329 83 39 0.47 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0005524 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0005524 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0005524 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0005524 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0005524 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPHB4 EPHB4 P54760 Ephrin type-B receptor 4 chr7 GO:0005524 Not Cancer Driver No 125 0.127 184 19 0.103 11
EPHB6_ENST00000422643 EPHB6 O15197 Ephrin type-B receptor 6 chr7 GO:0005524 Not Cancer Driver No 227 0.222 246 45 0.183 0
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 GO:0005524 Not Cancer Driver No 204 0.135 372 62 0.167 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0005524 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0005524 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0005524 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0005524 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0005524 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0005524 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC6L ERCC6L Q2NKX8 DNA excision repair protein ERCC-6-like chrX GO:0005524 Not Cancer Driver No 137 0.11 532 72 0.135 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0005524 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0005524 Not Cancer Driver No 192 0.207 213 45 0.211 0
ETNK1 ETNK1 Q9HBU6 Ethanolamine kinase 1 chr12 GO:0005524 Census Yes 49 0.108 81 5 0.062 0
ETNK2_ENST00000367202 ETNK2 Q9NVF9 Ethanolamine kinase 2 chr1 GO:0005524 Not Cancer Driver No 46 0.119 38 34 0.895 0
FAM20B FAM20B O75063 Glycosaminoglycan xylosylkinase chr1 GO:0005524 Not Cancer Driver No 50 0.122 3 1 0.333 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 GO:0005524 Not Cancer Driver No 33 0.057 188 3 0.016 9
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0005524 Not Cancer Driver No 268 0.131 898 128 0.143 0
FARS2_ENST00000274680 FARS2 O95363 Phenylalanine--tRNA ligase, mitochondrial chr6 GO:0005524 Not Cancer Driver No 66 0.146 73 17 0.233 4
FARSA FARSA Q9Y285 Phenylalanine--tRNA ligase alpha subunit chr19 GO:0005524 Not Cancer Driver No 75 0.148 120 25 0.208 0
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 GO:0005524 Not Cancer Driver No 71 0.121 0 0 0.0 8
FASTK FASTK Q14296 Fas-activated serine/threonine kinase chr7 GO:0005524 Not Cancer Driver No 65 0.118 143 12 0.084 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0005524 Not Cancer Driver No 139 0.133 192 32 0.167 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0005524 Not Cancer Driver No 114 0.139 145 21 0.145 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0005524 Census Yes 103 0.125 245 34 0.139 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0005524 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0005524 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0005524 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0005524 Census, Compendium Yes 113 0.141 162 28 0.173 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0005524 Not Cancer Driver No 85 0.161 52 8 0.154 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0005524 Not Cancer Driver No 46 0.1 42 3 0.071 0
FIGN FIGN Q5HY92 Fidgetin chr2 GO:0005524 Not Cancer Driver No 150 0.198 394 75 0.19 0
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0005524 Not Cancer Driver No 75 0.111 224 23 0.103 0
FIGNL2_ENST00000564840 FIGNL2 A6NMB9 Fidgetin-like protein 2 chr12 GO:0005524 Not Cancer Driver No 20 0.031 329 18 0.055 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0005524 Not Cancer Driver No 46 0.1 134 12 0.09 0
FLAD1 FLAD1 Q8NFF5 FAD synthase chr1 GO:0005524 Not Cancer Driver No 81 0.138 59 6 0.102 1
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0005524 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0005524 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0005524 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN3K FN3K Q9H479 Fructosamine-3-kinase chr17 GO:0005524 Not Cancer Driver No 36 0.117 40 3 0.075 0
FN3KRP FN3KRP Q9HA64 Ketosamine-3-kinase chr17 GO:0005524 Not Cancer Driver No 36 0.117 75 5 0.067 0
FPGS FPGS Q05932 Folylpolyglutamate synthase, mitochondrial chr9 GO:0005524 Not Cancer Driver No 68 0.116 141 18 0.128 0
FRK FRK P42685 Tyrosine-protein kinase FRK chr6 GO:0005524 Not Cancer Driver No 87 0.172 18 2 0.111 0
FUK FCSK Q8N0W3 L-fucose kinase chr16 GO:0005524 Not Cancer Driver No 102 0.094 26 1 0.038 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0005524 Not Cancer Driver No 92 0.171 70 13 0.186 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0005524 Not Cancer Driver No 85 0.182 352 65 0.185 0
GAK GAK O14976 Cyclin-G-associated kinase chr4 GO:0005524 Not Cancer Driver No 146 0.111 589 79 0.134 0
GALK1 GALK1 P51570 Galactokinase chr17 GO:0005524 Not Cancer Driver No 31 0.079 43 5 0.116 11
GALK2 GALK2 Q01415 N-acetylgalactosamine kinase chr15 GO:0005524 Not Cancer Driver No 48 0.105 17 1 0.059 0
GARS GARS1 P41250 Glycine--tRNA ligase chr7 GO:0005524 Not Cancer Driver No 61 0.083 75 9 0.12 17
GART_ENST00000381815 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 GO:0005524 Not Cancer Driver No 96 0.095 50 6 0.12 0
GATB GATB O75879 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial chr4 GO:0005524 Not Cancer Driver No 79 0.142 138 26 0.188 0
GATC GATC O43716 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial chr12 GO:0005524 Not Cancer Driver No 18 0.132 27 4 0.148 1
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0005524 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0005524 Not Cancer Driver No 73 0.115 167 18 0.108 3
GK GK P32189 Glycerol kinase chrX GO:0005524 Not Cancer Driver No 85 0.152 15 3 0.2 3
GK2 GK2 Q14410 Glycerol kinase 2 chr4 GO:0005524 Not Cancer Driver No 175 0.316 14 3 0.214 0
GK3P GK3P Q14409 Glycerol kinase 3 chr4 GO:0005524 Not Cancer Driver No 9 0.016 17 1 0.059 0
GK5 GK5 Q6ZS86 Putative glycerol kinase 5 chr3 GO:0005524 Not Cancer Driver No 42 0.079 9 1 0.111 0
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0005524 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0005524 Not Cancer Driver No 66 0.177 104 21 0.202 2
GLYCTK GLYCTK Q8IVS8 Glycerate kinase chr3 GO:0005524 Not Cancer Driver No 51 0.098 86 12 0.14 1
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 GO:0005524 Census, Compendium Yes 88 0.127 76 10 0.132 0
GNE_ENST00000539815 GNE Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase chr9 GO:0005524 Not Cancer Driver No 83 0.115 15 2 0.133 36
GPHN_ENST00000315266 GPHN Q9NQX3 Gephyrin chr14 GO:0005524 Census Yes 126 0.171 305 41 0.134 2
GRK1 GRK1 Q15835 Rhodopsin kinase GRK1 chr13 GO:0005524 Not Cancer Driver No 70 0.124 32 2 0.062 2
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 GO:0005524 Not Cancer Driver No 77 0.112 87 8 0.092 0
GRK3 GRK3 P35626 Beta-adrenergic receptor kinase 2 chr22 GO:0005524 Not Cancer Driver No 87 0.126 78 8 0.103 0
GRK4 GRK4 P32298 G protein-coupled receptor kinase 4 chr4 GO:0005524 Not Cancer Driver No 70 0.121 32 2 0.062 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 GO:0005524 Not Cancer Driver No 77 0.131 103 18 0.175 0
GRK6_ENST00000355472 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 GO:0005524 Not Cancer Driver No 65 0.113 68 10 0.147 0
GRK7 GRK7 Q8WTQ7 Rhodopsin kinase GRK7 chr3 GO:0005524 Not Cancer Driver No 110 0.199 88 19 0.216 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0005524 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0005524 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSS_ENST00000216951 GSS P48637 Glutathione synthetase chr20 GO:0005524 Not Cancer Driver No 61 0.129 49 6 0.122 14
GTF2F2 GTF2F2 P13984 General transcription factor IIF subunit 2 chr13 GO:0005524 Not Cancer Driver No 20 0.08 112 9 0.08 0
GUCY2C GUCY2C P25092 Guanylyl cyclase C chr12 GO:0005524 Not Cancer Driver No 209 0.195 51 7 0.137 2
GUCY2D GUCY2D Q02846 Retinal guanylyl cyclase 1 chr17 GO:0005524 Not Cancer Driver No 138 0.125 205 34 0.166 32
GUCY2F GUCY2F P51841 Retinal guanylyl cyclase 2 chrX GO:0005524 Not Cancer Driver No 230 0.208 88 15 0.17 0
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 GO:0005524 Not Cancer Driver No 28 0.142 71 9 0.127 0
H1FNT H1-7 Q75WM6 Testis-specific H1 histone chr12 GO:0005524 Not Cancer Driver No 54 0.212 251 54 0.215 0
HACL1 HACL1 Q9UJ83 2-hydroxyacyl-CoA lyase 1 chr3 GO:0005524 Not Cancer Driver No 70 0.121 28 4 0.143 0
HARS2_ENST00000642231 HARS2 P49590 Histidine--tRNA ligase, mitochondrial chr5 GO:0005524 Not Cancer Driver No 48 0.095 34 4 0.118 2
HARS_ENST00000644191 HARS1 P12081 Histidine--tRNA ligase, cytoplasmic chr5 GO:0005524 Not Cancer Driver No 65 0.128 17 2 0.118 7
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 GO:0005524 Not Cancer Driver No 87 0.109 373 36 0.097 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0005524 Not Cancer Driver No 112 0.213 124 25 0.202 0
HELB HELB Q8NG08 DNA helicase B chr12 GO:0005524 Not Cancer Driver No 140 0.129 300 38 0.127 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0005524 Not Cancer Driver No 78 0.093 227 25 0.11 0
HELQ HELQ Q8TDG4 Helicase POLQ-like chr4 GO:0005524 Not Cancer Driver No 134 0.122 273 19 0.07 0
HELZ2 HELZ2 Q9BYK8 Helicase with zinc finger domain 2 chr20 GO:0005524 Not Cancer Driver No 320 0.121 594 84 0.141 0
HELZ_ENST00000358691 HELZ P42694 Probable helicase with zinc finger domain chr17 GO:0005524 Not Cancer Driver No 234 0.12 873 110 0.126 0
HFM1 HFM1 A2PYH4 Probable ATP-dependent DNA helicase HFM1 chr1 GO:0005524 Not Cancer Driver No 252 0.176 373 60 0.161 2
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0005524 Not Cancer Driver No 158 0.131 565 89 0.158 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0005524 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0005524 Not Cancer Driver No 128 0.105 559 51 0.091 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 GO:0005524 Not Cancer Driver No 87 0.141 258 23 0.089 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0005524 Not Cancer Driver No 127 0.138 75 16 0.213 6
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0005524 Not Cancer Driver No 138 0.15 77 7 0.091 0
HK3 HK3 P52790 Hexokinase-3 chr5 GO:0005524 Not Cancer Driver No 164 0.178 71 17 0.239 0
HKDC1 HKDC1 Q2TB90 Hexokinase HKDC1 chr10 GO:0005524 Not Cancer Driver No 146 0.159 33 3 0.091 0
HLCS HLCS P50747 Biotin--protein ligase chr21 GO:0005524 Not Cancer Driver No 95 0.131 158 15 0.095 23
HLTF_ENST00000494055 HLTF Q14527 Helicase-like transcription factor chr3 GO:0005524 Not Cancer Driver No 121 0.12 353 40 0.113 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0005524 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0005524 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0005524 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0005524 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA12A_ENST00000369209 HSPA12A O43301 Heat shock 70 kDa protein 12A chr10 GO:0005524 Not Cancer Driver No 130 0.193 86 16 0.186 0
HSPA12B HSPA12B Q96MM6 Heat shock 70 kDa protein 12B chr20 GO:0005524 Not Cancer Driver No 75 0.109 126 18 0.143 0
HSPA13 HSPA13 P48723 Heat shock 70 kDa protein 13 chr21 GO:0005524 Not Cancer Driver No 74 0.157 48 7 0.146 0
HSPA14 HSPA14 Q0VDF9 Heat shock 70 kDa protein 14 chr10 GO:0005524 Not Cancer Driver No 52 0.102 22 0 0.0 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0005524 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0005524 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 GO:0005524 Not Cancer Driver No 119 0.186 141 28 0.199 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:0005524 Not Cancer Driver No 93 0.146 286 38 0.133 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 GO:0005524 Not Cancer Driver No 80 0.095 351 24 0.068 0
HSPA4L_ENST00000508776 HSPA4L O95757 Heat shock 70 kDa protein 4L chr4 GO:0005524 Not Cancer Driver No 105 0.125 266 28 0.105 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0005524 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 GO:0005524 Not Cancer Driver No 112 0.174 235 27 0.115 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0005524 Not Cancer Driver No 149 0.231 251 52 0.207 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 GO:0005524 Not Cancer Driver No 67 0.099 283 26 0.092 2
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0005524 Not Cancer Driver No 61 0.106 82 6 0.073 2
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 GO:0005524 Not Cancer Driver No 8 0.078 3 0 0.0 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0005524 Not Cancer Driver No 103 0.12 323 42 0.13 0
HUNK HUNK P57058 Hormonally up-regulated neu tumor-associated kinase chr21 GO:0005524 Not Cancer Driver No 112 0.157 323 50 0.155 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0005524 Not Cancer Driver No 132 0.132 373 47 0.126 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0005524 Not Cancer Driver No 130 0.103 28 4 0.143 4
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 GO:0005524 Not Cancer Driver No 149 0.147 145 22 0.152 0
ICK CILK1 Q9UPZ9 Serine/threonine-protein kinase ICK chr6 GO:0005524 Not Cancer Driver No 73 0.116 366 44 0.12 3
IDE IDE P14735 Insulin-degrading enzyme chr10 GO:0005524 Not Cancer Driver No 90 0.088 96 8 0.083 0
IDH3G IDH3G P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial chrX GO:0005524 Not Cancer Driver No 48 0.122 77 9 0.117 0
IDNK IDNK Q5T6J7 Probable gluconokinase chr9 GO:0005524 Not Cancer Driver No 19 0.102 27 5 0.185 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0005524 Not Cancer Driver No 109 0.106 287 36 0.125 9
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0005524 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGHMBP2 IGHMBP2 P38935 DNA-binding protein SMUBP-2 chr11 GO:0005524 Not Cancer Driver No 136 0.137 354 53 0.15 31
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0005524 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0005524 Not Cancer Driver No 108 0.151 76 13 0.171 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0005524 Not Cancer Driver No 45 0.1 71 9 0.127 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0005524 Compendium Yes 173 0.111 682 76 0.111 0
INSR INSR P06213 Insulin receptor chr19 GO:0005524 Not Cancer Driver No 190 0.137 280 57 0.204 64
INSRR INSRR P14616 Insulin receptor-related protein chr1 GO:0005524 Not Cancer Driver No 262 0.202 228 37 0.162 0
IP6K1 IP6K1 Q92551 Inositol hexakisphosphate kinase 1 chr3 GO:0005524 Not Cancer Driver No 50 0.113 216 29 0.134 0
IP6K2 IP6K2 Q9UHH9 Inositol hexakisphosphate kinase 2 chr3 GO:0005524 Not Cancer Driver No 45 0.106 96 10 0.104 0
IP6K3 IP6K3 Q96PC2 Inositol hexakisphosphate kinase 3 chr6 GO:0005524 Not Cancer Driver No 85 0.207 149 34 0.228 0
IPMK IPMK Q8NFU5 Inositol polyphosphate multikinase chr10 GO:0005524 Not Cancer Driver No 50 0.12 108 9 0.083 0
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0005524 Not Cancer Driver No 55 0.112 43 3 0.07 0
IQCA1L IQCA1L A6NCM1 IQ and AAA domain-containing protein 1-like chr7 GO:0005524 Not Cancer Driver No 6 0.007 261 3 0.011 0
IQCA1_ENST00000409907 IQCA1 Q86XH1 Dynein regulatory complex protein 11 chr2 GO:0005524 Not Cancer Driver No 157 0.191 172 27 0.157 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0005524 Compendium Yes 71 0.1 337 39 0.116 0
IRAK2 IRAK2 O43187 Interleukin-1 receptor-associated kinase-like 2 chr3 GO:0005524 Not Cancer Driver No 84 0.134 202 32 0.158 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0005524 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0005524 Not Cancer Driver No 68 0.148 116 20 0.172 2
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0005524 Census Yes 139 0.224 43 10 0.233 1
ITM2B ITM2B Q9Y287 Integral membrane protein 2B chr13 GO:0005524 Not Cancer Driver No 21 0.079 12 0 0.0 1
ITM2C ITM2C Q9NQX7 Integral membrane protein 2C chr2 GO:0005524 Not Cancer Driver No 31 0.116 33 4 0.121 0
ITPK1 ITPK1 Q13572 Inositol-tetrakisphosphate 1-kinase chr14 GO:0005524 Not Cancer Driver No 74 0.179 24 1 0.042 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0005524 Not Cancer Driver No 28 0.061 216 7 0.032 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0005524 Not Cancer Driver No 148 0.156 719 119 0.166 0
ITPKC ITPKC Q96DU7 Inositol-trisphosphate 3-kinase C chr19 GO:0005524 Not Cancer Driver No 78 0.114 452 38 0.084 0
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 GO:0005524 Census, Compendium Yes 147 0.127 120 7 0.058 2
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0005524 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0005524 Census, Compendium Yes 167 0.149 63 10 0.159 7
KALRN_ENST00000360013 KALRN O60229 Kalirin chr3 GO:0005524 Not Cancer Driver No 544 0.182 732 128 0.175 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0005524 Not Cancer Driver No 88 0.147 160 15 0.094 12
KATNA1 KATNA1 O75449 Katanin p60 ATPase-containing subunit A1 chr6 GO:0005524 Not Cancer Driver No 66 0.134 199 30 0.151 0
KATNAL1_ENST00000380617 KATNAL1 Q9BW62 Katanin p60 ATPase-containing subunit A-like 1 chr13 GO:0005524 Not Cancer Driver No 49 0.1 181 17 0.094 0
KATNAL2_ENST00000356157 KATNAL2 Q8IYT4 Katanin p60 ATPase-containing subunit A-like 2 chr18 GO:0005524 Not Cancer Driver No 84 0.156 142 30 0.211 0
KCNJ1 KCNJ1 P48048 ATP-sensitive inward rectifier potassium channel 1 chr11 GO:0005524 Not Cancer Driver No 83 0.212 10 0 0.0 13
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0005524 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0005524 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0005524 Not Cancer Driver No 99 0.233 68 22 0.324 1
KCNT2 KCNT2 Q6UVM3 Potassium channel subfamily T member 2 chr1 GO:0005524 Not Cancer Driver No 353 0.311 245 89 0.363 1
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0005524 Census, Compendium Yes 357 0.263 275 55 0.2 2
KHK_ENST00000260598 KHK P50053 Ketohexokinase chr2 GO:0005524 Not Cancer Driver No 38 0.128 42 4 0.095 2
KIAA0232_ENST00000425103 KIAA0232 Q92628 Uncharacterized protein KIAA0232 chr4 GO:0005524 Not Cancer Driver No 161 0.115 654 82 0.125 0
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 GO:0005524 Not Cancer Driver No 90 0.085 389 26 0.067 4
KIF12_ENST00000468460 KIF12 Q96FN5 Kinesin-like protein KIF12 chr9 GO:0005524 Not Cancer Driver No 81 0.125 299 31 0.104 0
KIF13A KIF13A Q9H1H9 Kinesin-like protein KIF13A chr6 GO:0005524 Not Cancer Driver No 220 0.122 816 103 0.126 0
KIF13B KIF13B Q9NQT8 Kinesin-like protein KIF13B chr8 GO:0005524 Not Cancer Driver No 187 0.102 968 82 0.085 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0005524 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIF15 KIF15 Q9NS87 Kinesin-like protein KIF15 chr3 GO:0005524 Not Cancer Driver No 148 0.107 819 93 0.114 0
KIF16B_ENST00000354981 KIF16B Q96L93 Kinesin-like protein KIF16B chr20 GO:0005524 Not Cancer Driver No 248 0.188 436 74 0.17 0
KIF17 KIF17 Q9P2E2 Kinesin-like protein KIF17 chr1 GO:0005524 Not Cancer Driver No 191 0.186 600 113 0.188 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0005524 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIF18B KIF18B Q86Y91 Kinesin-like protein KIF18B chr17 GO:0005524 Not Cancer Driver No 100 0.117 590 69 0.117 0
KIF19 KIF19 Q2TAC6 Kinesin-like protein KIF19 chr17 GO:0005524 Not Cancer Driver No 167 0.167 624 117 0.188 0
KIF1A_ENST00000320389 KIF1A Q12756 Kinesin-like protein KIF1A chr2 GO:0005524 Not Cancer Driver No 275 0.163 594 79 0.133 35
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 GO:0005524 Not Cancer Driver No 253 0.139 633 106 0.167 1
KIF1C KIF1C O43896 Kinesin-like protein KIF1C chr17 GO:0005524 Not Cancer Driver No 131 0.119 695 94 0.135 1
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 GO:0005524 Not Cancer Driver No 79 0.089 340 40 0.118 1
KIF20B KIF20B Q96Q89 Kinesin-like protein KIF20B chr10 GO:0005524 Not Cancer Driver No 217 0.119 902 109 0.121 0
KIF21A KIF21A Q7Z4S6 Kinesin-like protein KIF21A chr12 GO:0005524 Not Cancer Driver No 255 0.152 937 149 0.159 11
KIF21B KIF21B O75037 Kinesin-like protein KIF21B chr1 GO:0005524 Not Cancer Driver No 308 0.188 775 159 0.205 0
KIF22 KIF22 Q14807 Kinesin-like protein KIF22 chr16 GO:0005524 Not Cancer Driver No 79 0.119 322 35 0.109 4
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 GO:0005524 Not Cancer Driver No 102 0.106 559 62 0.111 0
KIF24 KIF24 Q5T7B8 Kinesin-like protein KIF24 chr9 GO:0005524 Not Cancer Driver No 126 0.092 898 90 0.1 0
KIF25_ENST00000443060 KIF25 Q9UIL4 Kinesin-like protein KIF25 chr6 GO:0005524 Not Cancer Driver No 80 0.208 143 37 0.259 0
KIF26A KIF26A Q9ULI4 Kinesin-like protein KIF26A chr14 GO:0005524 Not Cancer Driver No 154 0.082 1422 112 0.079 0
KIF26B KIF26B Q2KJY2 Kinesin-like protein KIF26B chr1 GO:0005524 Not Cancer Driver No 369 0.175 1412 198 0.14 0
KIF27 KIF27 Q86VH2 Kinesin-like protein KIF27 chr9 GO:0005524 Not Cancer Driver No 178 0.127 722 95 0.132 0
KIF2A_ENST00000401507 KIF2A O00139 Kinesin-like protein KIF2A chr5 GO:0005524 Not Cancer Driver No 74 0.105 336 37 0.11 2
KIF2B KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 GO:0005524 Not Cancer Driver No 314 0.467 189 116 0.614 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 GO:0005524 Not Cancer Driver No 110 0.152 337 63 0.187 0
KIF3A_ENST00000378746 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 GO:0005524 Not Cancer Driver No 92 0.132 409 59 0.144 0
KIF3B KIF3B O15066 Kinesin-like protein KIF3B chr20 GO:0005524 Not Cancer Driver No 105 0.141 485 69 0.142 2
KIF3C_ENST00000405914 KIF3C O14782 Kinesin-like protein KIF3C chr2 GO:0005524 Not Cancer Driver No 111 0.14 524 75 0.143 0
KIF4A KIF4A O95239 Chromosome-associated kinesin KIF4A chrX GO:0005524 Not Cancer Driver No 188 0.153 674 116 0.172 0
KIF4B KIF4B Q2VIQ3 Chromosome-associated kinesin KIF4B chr5 GO:0005524 Not Cancer Driver No 303 0.246 571 150 0.263 0
KIF5A KIF5A Q12840 Kinesin heavy chain isoform 5A chr12 GO:0005524 Not Cancer Driver No 194 0.188 569 103 0.181 14
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0005524 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIF5C KIF5C O60282 Kinesin heavy chain isoform 5C chr2 GO:0005524 Not Cancer Driver No 155 0.162 578 93 0.161 2
KIF6 KIF6 Q6ZMV9 Kinesin-like protein KIF6 chr6 GO:0005524 Not Cancer Driver No 183 0.225 314 68 0.217 0
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 GO:0005524 Not Cancer Driver No 150 0.112 844 104 0.123 5
KIF9_ENST00000452770 KIF9 Q9HAQ2 Kinesin-like protein KIF9 chr3 GO:0005524 Not Cancer Driver No 94 0.119 213 42 0.197 0
KIFC1 KIFC1 Q9BW19 Kinesin-like protein KIFC1 chr6 GO:0005524 Compendium Yes 99 0.147 450 67 0.149 0
KIFC2 KIFC2 Q96AC6 Kinesin-like protein KIFC2 chr8 GO:0005524 Not Cancer Driver No 84 0.1 605 55 0.091 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 GO:0005524 Not Cancer Driver No 84 0.101 487 42 0.086 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0005524 Census, Compendium Yes 226 0.232 83 33 0.398 21
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 GO:0005524 Not Cancer Driver No 114 0.124 404 58 0.144 0
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 GO:0005524 Not Cancer Driver No 231 0.243 434 120 0.276 0
KTI12 KTI12 Q96EK9 Protein KTI12 homolog chr1 GO:0005524 Not Cancer Driver No 37 0.105 176 18 0.102 0
LANCL2 LANCL2 Q9NS86 LanC-like protein 2 chr7 GO:0005524 Not Cancer Driver No 71 0.158 44 5 0.114 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0005524 Not Cancer Driver No 133 0.113 97 10 0.103 1
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 GO:0005524 Not Cancer Driver No 74 0.082 80 8 0.1 3
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0005524 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0005524 Census, Compendium Yes 178 0.164 687 116 0.169 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0005524 Census Yes 86 0.169 94 13 0.138 1
LIG1 LIG1 P18858 DNA ligase 1 chr19 GO:0005524 Not Cancer Driver No 137 0.149 397 62 0.156 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0005524 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0005524 Not Cancer Driver No 134 0.147 63 10 0.159 2
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0005524 Not Cancer Driver No 110 0.17 170 30 0.176 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 GO:0005524 Not Cancer Driver No 93 0.146 146 29 0.199 0
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 GO:0005524 Not Cancer Driver No 211 0.14 1018 141 0.139 0
LMTK3_ENST00000600059 LMTK3 Q96Q04 Serine/threonine-protein kinase LMTK3 chr19 GO:0005524 Not Cancer Driver No 115 0.079 1098 68 0.062 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0005524 Not Cancer Driver No 99 0.103 175 15 0.086 10
LONP2 LONP2 Q86WA8 Lon protease homolog 2, peroxisomal chr16 GO:0005524 Not Cancer Driver No 116 0.136 163 26 0.16 0
LRGUK LRGUK Q96M69 Leucine-rich repeat and guanylate kinase domain-containing protein chr7 GO:0005524 Not Cancer Driver No 145 0.176 204 37 0.181 0
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 GO:0005524 Not Cancer Driver No 289 0.143 261 33 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0005524 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0005524 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0005524 Census Yes 95 0.186 84 12 0.143 0
MAB21L1 MAB21L1 Q13394 Putative nucleotidyltransferase MAB21L1 chr13 GO:0005524 Not Cancer Driver No 94 0.262 0 0 0.0 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 GO:0005524 Not Cancer Driver No 260 0.174 1212 220 0.182 0
MAGI3 MAGI3 Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 chr1 GO:0005524 Not Cancer Driver No 154 0.104 1039 105 0.101 0
MAK_ENST00000474039 MAK P20794 Serine/threonine-protein kinase MAK chr6 GO:0005524 Not Cancer Driver No 80 0.128 323 51 0.158 5
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0005524 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0005524 Census Yes 58 0.145 105 14 0.133 4
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0005524 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0005524 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0005524 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0005524 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0005524 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K1 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 GO:0005524 Census, Compendium Yes 184 0.122 820 62 0.076 3
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0005524 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0005524 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0005524 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0005524 Census Yes 157 0.163 593 91 0.153 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 GO:0005524 Not Cancer Driver No 94 0.099 543 52 0.096 0
MAP3K15 MAP3K15 Q6ZN16 Mitogen-activated protein kinase kinase kinase 15 chrX GO:0005524 Not Cancer Driver No 206 0.157 315 39 0.124 0
MAP3K19 MAP3K19 Q56UN5 Mitogen-activated protein kinase kinase kinase 19 chr2 GO:0005524 Not Cancer Driver No 272 0.205 805 164 0.204 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0005524 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K21 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 GO:0005524 Not Cancer Driver No 191 0.184 658 112 0.17 0
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 GO:0005524 Not Cancer Driver No 75 0.121 313 47 0.15 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0005524 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0005524 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0005524 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K6 MAP3K6 O95382 Mitogen-activated protein kinase kinase kinase 6 chr1 GO:0005524 Not Cancer Driver No 108 0.084 390 31 0.079 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0005524 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP3K8_ENST00000542547 MAP3K8 P41279 Mitogen-activated protein kinase kinase kinase 8 chr10 GO:0005524 Not Cancer Driver No 58 0.124 109 10 0.092 0
MAP3K9_ENST00000554752 MAP3K9 P80192 Mitogen-activated protein kinase kinase kinase 9 chr14 GO:0005524 Not Cancer Driver No 167 0.151 684 104 0.152 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0005524 Not Cancer Driver No 116 0.139 276 41 0.149 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0005524 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAP4K3 MAP4K3 Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 chr2 GO:0005524 Not Cancer Driver No 116 0.13 313 45 0.144 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0005524 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAP4K5 MAP4K5 Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 chr14 GO:0005524 Not Cancer Driver No 69 0.082 236 23 0.097 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 GO:0005524 Not Cancer Driver No 88 0.19 107 16 0.15 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0005524 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0005524 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0005524 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0005524 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0005524 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0005524 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0005524 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK4 MAPK4 P31152 Mitogen-activated protein kinase 4 chr18 GO:0005524 Not Cancer Driver No 111 0.189 222 42 0.189 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 GO:0005524 Not Cancer Driver No 79 0.11 165 20 0.121 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0005524 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0005524 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0005524 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0005524 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKAPK3 MAPKAPK3 Q16644 MAP kinase-activated protein kinase 3 chr3 GO:0005524 Not Cancer Driver No 35 0.092 117 12 0.103 1
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0005524 Not Cancer Driver No 51 0.108 101 12 0.119 0
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0005524 Not Cancer Driver No 161 0.203 454 108 0.238 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0005524 Compendium Yes 124 0.157 445 70 0.157 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 GO:0005524 Not Cancer Driver No 92 0.122 376 49 0.13 1
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 GO:0005524 Not Cancer Driver No 94 0.125 403 46 0.114 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0005524 Not Cancer Driver No 91 0.101 151 16 0.106 8
MARS2 MARS2 Q96GW9 Methionine--tRNA ligase, mitochondrial chr2 GO:0005524 Not Cancer Driver No 75 0.126 34 6 0.176 1
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 GO:0005524 Not Cancer Driver No 204 0.13 1078 119 0.11 1
MAST2 MAST2 Q6P0Q8 Microtubule-associated serine/threonine-protein kinase 2 chr1 GO:0005524 Not Cancer Driver No 187 0.104 1326 133 0.1 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 GO:0005524 Not Cancer Driver No 169 0.129 783 100 0.128 0
MAST4 MAST4 O15021 Microtubule-associated serine/threonine-protein kinase 4 chr5 GO:0005524 Not Cancer Driver No 317 0.121 2099 256 0.122 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0005524 Not Cancer Driver No 90 0.102 389 44 0.113 0
MAT1A MAT1A Q00266 S-adenosylmethionine synthase isoform type-1 chr10 GO:0005524 Not Cancer Driver No 74 0.187 15 0 0.0 12
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 GO:0005524 Not Cancer Driver No 36 0.091 31 4 0.129 0
MATK_ENST00000310132 MATK P42679 Megakaryocyte-associated tyrosine-protein kinase chr19 GO:0005524 Not Cancer Driver No 94 0.185 146 27 0.185 0
MCCC1 MCCC1 Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial chr3 GO:0005524 Not Cancer Driver No 94 0.13 162 17 0.105 33
MCCC2 MCCC2 Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial chr5 GO:0005524 Not Cancer Driver No 60 0.107 25 2 0.08 52
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0005524 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 GO:0005524 Not Cancer Driver No 92 0.114 310 47 0.152 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 GO:0005524 Not Cancer Driver No 121 0.14 215 35 0.163 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 GO:0005524 Not Cancer Driver No 88 0.12 109 20 0.183 1
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 GO:0005524 Not Cancer Driver No 101 0.123 122 13 0.107 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0005524 Not Cancer Driver No 101 0.14 128 22 0.172 0
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0005524 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0005524 Not Cancer Driver No 56 0.049 523 13 0.025 0
MCMDC2 MCMDC2 Q4G0Z9 Minichromosome maintenance domain-containing protein 2 chr8 GO:0005524 Not Cancer Driver No 98 0.144 0 0 0.0 0
MDN1 MDN1 Q9NU22 Midasin chr6 GO:0005524 Not Cancer Driver No 678 0.121 983 107 0.109 0
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 GO:0005524 Not Cancer Driver No 76 0.117 162 24 0.148 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0005524 Not Cancer Driver No 175 0.175 159 31 0.195 3
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0005524 Census, Compendium Yes 226 0.163 62 15 0.242 19
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0005524 Not Cancer Driver No 113 0.085 740 56 0.076 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 GO:0005524 Not Cancer Driver No 540 0.166 3169 529 0.167 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0005524 Not Cancer Driver No 56 0.098 6 1 0.167 22
MKNK1 MKNK1 Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 chr1 GO:0005524 Not Cancer Driver No 54 0.116 149 24 0.161 0
MKNK2_ENST00000591601 MKNK2 Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 chr19 GO:0005524 Not Cancer Driver No 42 0.09 124 8 0.065 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0005524 Census Yes 92 0.122 208 22 0.106 85
MLH3_ENST00000556740 MLH3 Q9UHC1 DNA mismatch repair protein Mlh3 chr14 GO:0005524 Not Cancer Driver No 154 0.106 593 60 0.101 9
MLKL MLKL Q8NB16 Mixed lineage kinase domain-like protein chr16 GO:0005524 Not Cancer Driver No 56 0.119 89 15 0.169 0
MMAB MMAB Q96EY8 Corrinoid adenosyltransferase MMAB chr12 GO:0005524 Not Cancer Driver No 36 0.144 68 14 0.206 5
MOCS3 MOCS3 O95396 Adenylyltransferase and sulfurtransferase MOCS3 chr20 GO:0005524 Not Cancer Driver No 61 0.133 15 5 0.333 0
MOK MOK Q9UQ07 MAPK/MAK/MRK overlapping kinase chr14 GO:0005524 Not Cancer Driver No 44 0.105 135 13 0.096 0
MORC2 MORC2 Q9Y6X9 ATPase MORC2 chr22 GO:0005524 Not Cancer Driver No 125 0.121 523 69 0.132 16
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 GO:0005524 Not Cancer Driver No 94 0.272 16 4 0.25 0
MOV10L1_ENST00000545383 MOV10L1 Q9BXT6 RNA helicase Mov10l1 chr22 GO:0005524 Not Cancer Driver No 184 0.152 178 21 0.118 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0005524 Not Cancer Driver No 110 0.11 101 8 0.079 0
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 GO:0005524 Not Cancer Driver No 70 0.104 337 33 0.098 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0005524 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0005524 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH4 MSH4 O15457 MutS protein homolog 4 chr1 GO:0005524 Not Cancer Driver No 199 0.213 196 42 0.214 0
MSH5_ENST00000375755 MSH5 O43196 MutS protein homolog 5 chr6 GO:0005524 Not Cancer Driver No 101 0.121 86 4 0.047 1
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0005524 Census Yes 154 0.113 386 41 0.106 6
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0005524 Not Cancer Driver No 178 0.127 182 27 0.148 1
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0005524 Not Cancer Driver No 103 0.11 129 11 0.085 6
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 GO:0005524 Not Cancer Driver No 117 0.12 139 11 0.079 0
MTHFS MTHFS P49914 5-formyltetrahydrofolate cyclo-ligase chr15 GO:0005524 Not Cancer Driver No 18 0.089 36 6 0.167 2
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0005524 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0005524 Not Cancer Driver No 73 0.125 136 22 0.162 1
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0005524 Not Cancer Driver No 117 0.112 160 15 0.094 0
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0005524 Not Cancer Driver No 188 0.216 35 7 0.2 7
MVD MVD P53602 Diphosphomevalonate decarboxylase chr16 GO:0005524 Not Cancer Driver No 47 0.117 49 10 0.204 3
MVK MVK Q03426 Mevalonate kinase chr12 GO:0005524 Not Cancer Driver No 50 0.126 25 0 0.0 38
MYH1 MYH1 P12882 Myosin-1 chr17 GO:0005524 Not Cancer Driver No 546 0.282 1153 335 0.291 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 GO:0005524 Not Cancer Driver No 258 0.131 1134 136 0.12 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 GO:0005524 Census, Compendium Yes 353 0.179 1180 201 0.17 2
MYH13 MYH13 Q9UKX3 Myosin-13 chr17 GO:0005524 Not Cancer Driver No 452 0.233 1082 237 0.219 0
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 GO:0005524 Not Cancer Driver No 275 0.138 1215 169 0.139 5
MYH15 MYH15 Q9Y2K3 Myosin-15 chr3 GO:0005524 Not Cancer Driver No 379 0.195 882 176 0.2 0
MYH2_ENST00000397183 MYH2 Q9UKX2 Myosin-2 chr17 GO:0005524 Not Cancer Driver No 572 0.295 1073 338 0.315 1
MYH3 MYH3 P11055 Myosin-3 chr17 GO:0005524 Not Cancer Driver No 312 0.161 967 179 0.185 14
MYH4 MYH4 Q9Y623 Myosin-4 chr17 GO:0005524 Not Cancer Driver No 464 0.239 1138 288 0.253 0
MYH6 MYH6 P13533 Myosin-6 chr14 GO:0005524 Not Cancer Driver No 392 0.202 1112 238 0.214 7
MYH7 MYH7 P12883 Myosin-7 chr14 GO:0005524 Not Cancer Driver No 464 0.24 1107 276 0.249 200
MYH7B MYH7B A7E2Y1 Myosin-7B chr20 GO:0005524 Not Cancer Driver No 294 0.148 1103 138 0.125 0
MYH8 MYH8 P13535 Myosin-8 chr17 GO:0005524 Not Cancer Driver No 498 0.257 1086 315 0.29 2
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0005524 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0005524 Not Cancer Driver No 343 0.179 957 184 0.192 3
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 GO:0005524 Not Cancer Driver No 118 0.198 277 64 0.231 2
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0005524 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 GO:0005524 Not Cancer Driver No 67 0.173 77 14 0.182 0
MYO10 MYO10 Q9HD67 Unconventional myosin-X chr5 GO:0005524 Not Cancer Driver No 296 0.144 418 59 0.141 0
MYO15A_ENST00000647165 MYO15A Q9UKN7 Unconventional myosin-XV chr17 GO:0005524 Not Cancer Driver No 471 0.133 1386 172 0.124 4
MYO15B_ENST00000633867 MYO15B Q96JP2 Unconventional myosin-XVB chr17 GO:0005524 Not Cancer Driver No 28 0.018 771 14 0.018 0
MYO16_ENST00000357550 MYO16 Q9Y6X6 Unconventional myosin-XVI chr13 GO:0005524 Not Cancer Driver No 412 0.222 681 112 0.164 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 GO:0005524 Not Cancer Driver No 268 0.13 1237 176 0.142 0
MYO18B_ENST00000335473 MYO18B Q8IUG5 Unconventional myosin-XVIIIb chr22 GO:0005524 Not Cancer Driver No 541 0.211 1541 355 0.23 0
MYO1A MYO1A Q9UBC5 Unconventional myosin-Ia chr12 GO:0005524 Not Cancer Driver No 170 0.163 57 5 0.088 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 GO:0005524 Not Cancer Driver No 144 0.127 34 4 0.118 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0005524 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 GO:0005524 Not Cancer Driver No 126 0.125 61 6 0.098 0
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 GO:0005524 Not Cancer Driver No 137 0.124 229 14 0.061 1
MYO1F MYO1F O00160 Unconventional myosin-If chr19 GO:0005524 Not Cancer Driver No 209 0.19 246 48 0.195 0
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 GO:0005524 Not Cancer Driver No 125 0.123 117 12 0.103 0
MYO1H MYO1H Q8N1T3 Unconventional myosin-Ih chr12 GO:0005524 Not Cancer Driver No 154 0.149 8 2 0.25 0
MYO3A MYO3A Q8NEV4 Myosin-IIIa chr10 GO:0005524 Not Cancer Driver No 454 0.281 552 172 0.312 0
MYO3B MYO3B Q8WXR4 Myosin-IIIb chr2 GO:0005524 Not Cancer Driver No 242 0.18 308 58 0.188 0
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 GO:0005524 Census, Compendium Yes 224 0.121 497 58 0.117 0
MYO5B MYO5B Q9ULV0 Unconventional myosin-Vb chr18 GO:0005524 Not Cancer Driver No 269 0.146 505 68 0.135 14
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 GO:0005524 Not Cancer Driver No 204 0.117 394 43 0.109 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0005524 Not Cancer Driver No 176 0.136 342 41 0.12 3
MYO7A MYO7A Q13402 Unconventional myosin-VIIa chr11 GO:0005524 Not Cancer Driver No 298 0.135 369 58 0.157 50
MYO7B_ENST00000409816 MYO7B Q6PIF6 Unconventional myosin-VIIb chr2 GO:0005524 Not Cancer Driver No 375 0.177 216 41 0.19 0
MYO9A MYO9A B2RTY4 Unconventional myosin-IXa chr15 GO:0005524 Not Cancer Driver No 323 0.127 970 131 0.135 0
MYO9B_ENST00000594824 MYO9B Q13459 Unconventional myosin-IXb chr19 GO:0005524 Not Cancer Driver No 226 0.105 827 80 0.097 0
N4BP2 N4BP2 Q86UW6 NEDD4-binding protein 2 chr4 GO:0005524 Census Yes 185 0.105 965 104 0.108 0
NADK2 NADK2 Q4G0N4 NAD kinase 2, mitochondrial chr5 GO:0005524 Not Cancer Driver No 42 0.095 89 3 0.034 0
NADK_ENST00000341991 NADK O95544 NAD kinase chr1 GO:0005524 Not Cancer Driver No 59 0.132 91 18 0.198 0
NADSYN1 NADSYN1 Q6IA69 Glutamine-dependent NAD(+) synthetase chr11 GO:0005524 Not Cancer Driver No 82 0.116 27 8 0.296 3
NAGK_ENST00000244204 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 GO:0005524 Not Cancer Driver No 46 0.134 5 1 0.2 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0005524 Not Cancer Driver No 39 0.028 67 4 0.06 0
NARS NARS1 O43776 Asparagine--tRNA ligase, cytoplasmic chr18 GO:0005524 Not Cancer Driver No 50 0.091 103 16 0.155 4
NARS2 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 GO:0005524 Not Cancer Driver No 79 0.166 22 2 0.091 3
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0005524 Not Cancer Driver No 109 0.106 142 18 0.127 0
NAV2 NAV2 Q8IVL1 Neuron navigator 2 chr11 GO:0005524 Not Cancer Driver No 367 0.148 1866 276 0.148 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0005524 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0005524 Not Cancer Driver No 29 0.201 24 4 0.167 1
NEK10_ENST00000429845 NEK10 Q6ZWH5 Serine/threonine-protein kinase Nek10 chr3 GO:0005524 Not Cancer Driver No 213 0.182 281 60 0.214 0
NEK11 NEK11 Q8NG66 Serine/threonine-protein kinase Nek11 chr3 GO:0005524 Not Cancer Driver No 91 0.141 264 45 0.17 0
NEK1_ENST00000439128 NEK1 Q96PY6 Serine/threonine-protein kinase Nek1 chr4 GO:0005524 Not Cancer Driver No 131 0.104 879 98 0.111 3
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0005524 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK3 NEK3 P51956 Serine/threonine-protein kinase Nek3 chr13 GO:0005524 Not Cancer Driver No 44 0.087 203 17 0.084 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 GO:0005524 Not Cancer Driver No 78 0.093 492 49 0.1 0
NEK5_ENST00000617045 NEK5 Q6P3R8 Serine/threonine-protein kinase Nek5 chr13 GO:0005524 Not Cancer Driver No 142 0.201 300 61 0.203 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 GO:0005524 Not Cancer Driver No 31 0.099 36 0 0.0 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0005524 Not Cancer Driver No 35 0.116 23 0 0.0 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 GO:0005524 Not Cancer Driver No 102 0.147 167 40 0.24 3
NEK9 NEK9 Q8TD19 Serine/threonine-protein kinase Nek9 chr14 GO:0005524 Not Cancer Driver No 88 0.09 330 34 0.103 3
NIM1K NIM1K Q8IY84 Serine/threonine-protein kinase NIM1 chr5 GO:0005524 Not Cancer Driver No 73 0.167 126 21 0.167 0
NLK NLK Q9UBE8 Serine/threonine-protein kinase NLK chr17 GO:0005524 Not Cancer Driver No 54 0.102 152 20 0.132 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0005524 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0005524 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0005524 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0005524 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRP11 NLRP11 P59045 NACHT, LRR and PYD domains-containing protein 11 chr19 GO:0005524 Not Cancer Driver No 229 0.222 25 2 0.08 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0005524 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP13 NLRP13 Q86W25 NACHT, LRR and PYD domains-containing protein 13 chr19 GO:0005524 Not Cancer Driver No 298 0.286 121 46 0.38 0
NLRP14 NLRP14 Q86W24 NACHT, LRR and PYD domains-containing protein 14 chr11 GO:0005524 Not Cancer Driver No 241 0.22 46 8 0.174 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0005524 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP2 NLRP2 Q9NX02 NACHT, LRR and PYD domains-containing protein 2 chr19 GO:0005524 Not Cancer Driver No 257 0.242 60 15 0.25 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0005524 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP4 NLRP4 Q96MN2 NACHT, LRR and PYD domains-containing protein 4 chr19 GO:0005524 Not Cancer Driver No 352 0.354 26 14 0.538 0
NLRP5 NLRP5 P59047 NACHT, LRR and PYD domains-containing protein 5 chr19 GO:0005524 Not Cancer Driver No 369 0.307 144 35 0.243 0
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0005524 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0005524 Not Cancer Driver No 300 0.306 71 20 0.282 9
NLRP8 NLRP8 Q86W28 NACHT, LRR and PYD domains-containing protein 8 chr19 GO:0005524 Not Cancer Driver No 329 0.314 50 16 0.32 0
NLRP9 NLRP9 Q7RTR0 NACHT, LRR and PYD domains-containing protein 9 chr19 GO:0005524 Not Cancer Driver No 247 0.249 0 0 0.0 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0005524 Not Cancer Driver No 158 0.162 94 13 0.138 0
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0005524 Not Cancer Driver No 11 0.072 10 0 0.0 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0005524 Not Cancer Driver No 13 0.086 11 1 0.091 0
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 GO:0005524 Not Cancer Driver No 10 0.059 4 0 0.0 0
NME4 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 GO:0005524 Not Cancer Driver No 13 0.07 41 4 0.098 0
NME6_ENST00000415053 NME6 O75414 Nucleoside diphosphate kinase 6 chr3 GO:0005524 Not Cancer Driver No 23 0.124 22 3 0.136 0
NME7 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 GO:0005524 Not Cancer Driver No 53 0.141 0 0 0.0 0
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 GO:0005524 Not Cancer Driver No 39 0.14 49 7 0.143 28
NMNAT2 NMNAT2 Q9BZQ4 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 chr1 GO:0005524 Not Cancer Driver No 54 0.176 22 1 0.045 0
NMNAT3 NMNAT3 Q96T66 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 chr3 GO:0005524 Not Cancer Driver No 32 0.127 53 6 0.113 0
NMRK1_ENST00000361092 NMRK1 Q9NWW6 Nicotinamide riboside kinase 1 chr9 GO:0005524 Not Cancer Driver No 23 0.116 6 0 0.0 0
NMRK2_ENST00000168977 NMRK2 Q9NPI5 Nicotinamide riboside kinase 2 chr19 GO:0005524 Not Cancer Driver No 25 0.109 53 9 0.17 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0005524 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0005524 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 GO:0005524 Not Cancer Driver No 73 0.104 102 8 0.078 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 GO:0005524 Not Cancer Driver No 74 0.106 662 69 0.104 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0005524 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0005524 Not Cancer Driver No 144 0.138 89 18 0.202 20
NRBP1_ENST00000379852 NRBP1 Q9UHY1 Nuclear receptor-binding protein chr2 GO:0005524 Not Cancer Driver No 64 0.12 189 29 0.153 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 GO:0005524 Not Cancer Driver No 30 0.06 110 5 0.045 0
NRK NRK Q7Z2Y5 Nik-related protein kinase chrX GO:0005524 Compendium Yes 315 0.199 812 159 0.196 0
NSF NSF P46459 Vesicle-fusing ATPase chr17 GO:0005524 Not Cancer Driver No 47 0.063 84 3 0.036 2
NTPCR NTPCR Q9BSD7 Cancer-related nucleoside-triphosphatase chr1 GO:0005524 Not Cancer Driver No 30 0.158 31 2 0.065 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0005524 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0005524 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0005524 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0005524 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUBP1 NUBP1 P53384 Cytosolic Fe-S cluster assembly factor NUBP1 chr16 GO:0005524 Not Cancer Driver No 31 0.097 62 6 0.097 0
NUBP2 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 GO:0005524 Not Cancer Driver No 38 0.14 14 0 0.0 0
NUBPL NUBPL Q8TB37 Iron-sulfur protein NUBPL chr14 GO:0005524 Not Cancer Driver No 32 0.1 49 1 0.02 2
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0005524 Not Cancer Driver No 90 0.105 267 31 0.116 0
NWD1_ENST00000552788 NWD1 Q149M9 NACHT domain- and WD repeat-containing protein 1 chr19 GO:0005524 Not Cancer Driver No 323 0.207 87 15 0.172 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0005524 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS2 OAS2 P29728 2'-5'-oligoadenylate synthase 2 chr12 GO:0005524 Not Cancer Driver No 141 0.196 47 14 0.298 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0005524 Not Cancer Driver No 139 0.128 147 17 0.116 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 GO:0005524 Not Cancer Driver No 1208 0.152 2623 368 0.14 0
OLA1 OLA1 Q9NTK5 Obg-like ATPase 1 chr2 GO:0005524 Not Cancer Driver No 41 0.104 40 5 0.125 0
OPLAH OPLAH O14841 5-oxoprolinase chr8 GO:0005524 Not Cancer Driver No 141 0.109 323 37 0.115 0
ORC1_ENST00000371566 ORC1 Q13415 Origin recognition complex subunit 1 chr1 GO:0005524 Not Cancer Driver No 100 0.116 338 46 0.136 5
ORC4_ENST00000392857 ORC4 O43929 Origin recognition complex subunit 4 chr2 GO:0005524 Not Cancer Driver No 52 0.119 14 2 0.143 1
ORC5 ORC5 O43913 Origin recognition complex subunit 5 chr7 GO:0005524 Not Cancer Driver No 43 0.099 16 2 0.125 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0005524 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0005524 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0005524 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0005524 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0005524 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0005524 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX6 P2RX6 O15547 P2X purinoceptor 6 chr22 GO:0005524 Not Cancer Driver No 33 0.075 43 1 0.023 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0005524 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0005524 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0005524 Not Cancer Driver No 66 0.181 10 2 0.2 0
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 GO:0005524 Not Cancer Driver No 23 0.054 35 3 0.086 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0005524 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0005524 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0005524 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 GO:0005524 Not Cancer Driver No 58 0.098 340 33 0.097 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 GO:0005524 Not Cancer Driver No 226 0.314 407 123 0.302 0
PAK6_ENST00000260404 PAK6 Q9NQU5 Serine/threonine-protein kinase PAK 6 chr15 GO:0005524 Not Cancer Driver No 82 0.12 398 52 0.131 0
PALM3 PALM3 A6NDB9 Paralemmin-3 chr19 GO:0005524 Not Cancer Driver No 26 0.039 635 23 0.036 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0005524 Not Cancer Driver No 104 0.117 323 35 0.108 0
PANK1 PANK1 Q8TE04 Pantothenate kinase 1 chr10 GO:0005524 Not Cancer Driver No 62 0.104 248 17 0.069 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0005524 Not Cancer Driver No 46 0.081 206 14 0.068 30
PANK3 PANK3 Q9H999 Pantothenate kinase 3 chr5 GO:0005524 Not Cancer Driver No 41 0.111 0 0 0.0 0
PANK4 PANK4 Q9NVE7 4'-phosphopantetheine phosphatase chr1 GO:0005524 Not Cancer Driver No 92 0.119 71 15 0.211 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 GO:0005524 Not Cancer Driver No 97 0.13 293 28 0.096 0
PAPOLB PAPOLB Q9NRJ5 Poly(A) polymerase beta chr7 GO:0005524 Not Cancer Driver No 132 0.207 155 35 0.226 0
PAPOLG PAPOLG Q9BWT3 Poly(A) polymerase gamma chr2 GO:0005524 Not Cancer Driver No 94 0.128 303 35 0.116 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 GO:0005524 Not Cancer Driver No 94 0.151 82 14 0.171 0
PAPSS2_ENST00000361175 PAPSS2 O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 chr10 GO:0005524 Not Cancer Driver No 81 0.132 100 7 0.07 4
PARS2 PARS2 Q7L3T8 Probable proline--tRNA ligase, mitochondrial chr1 GO:0005524 Not Cancer Driver No 50 0.105 8 2 0.25 0
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 GO:0005524 Not Cancer Driver No 181 0.137 412 62 0.15 0
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0005524 Not Cancer Driver No 23 0.071 92 6 0.065 0
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 GO:0005524 Not Cancer Driver No 185 0.157 172 27 0.157 9
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 GO:0005524 Not Cancer Driver No 102 0.14 42 14 0.333 16
PCCB_ENST00000251654 PCCB P05166 Propionyl-CoA carboxylase beta chain, mitochondrial chr3 GO:0005524 Not Cancer Driver No 59 0.109 64 12 0.188 25
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0005524 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0005524 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDIK1L PDIK1L Q8N165 Serine/threonine-protein kinase PDIK1L chr1 GO:0005524 Not Cancer Driver No 36 0.106 5 0 0.0 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 GO:0005524 Not Cancer Driver No 52 0.119 50 10 0.2 0
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0005524 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0005524 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0005524 Not Cancer Driver No 70 0.17 14 2 0.143 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0005524 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDXK PDXK O00764 Pyridoxal kinase chr21 GO:0005524 Not Cancer Driver No 27 0.087 47 6 0.128 2
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 GO:0005524 Not Cancer Driver No 222 0.127 1232 150 0.122 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 GO:0005524 Not Cancer Driver No 23 0.123 76 13 0.171 0
PEX1 PEX1 O43933 Peroxisome biogenesis factor 1 chr7 GO:0005524 Not Cancer Driver No 143 0.111 304 36 0.118 14
PEX6 PEX6 Q13608 Peroxisome assembly factor 2 chr6 GO:0005524 Not Cancer Driver No 72 0.073 177 9 0.051 11
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 GO:0005524 Not Cancer Driver No 157 0.117 380 36 0.095 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0005524 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0005524 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 GO:0005524 Not Cancer Driver No 65 0.125 97 19 0.196 0
PFKFB4 PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 chr3 GO:0005524 Not Cancer Driver No 71 0.151 44 3 0.068 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0005524 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0005524 Not Cancer Driver No 80 0.103 70 8 0.114 9
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:0005524 Not Cancer Driver No 133 0.17 43 10 0.233 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX GO:0005524 Not Cancer Driver No 61 0.146 40 5 0.125 9
PGK2 PGK2 P07205 Phosphoglycerate kinase 2 chr6 GO:0005524 Not Cancer Driver No 145 0.348 37 13 0.351 0
PGS1 PGS1 Q32NB8 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial chr17 GO:0005524 Not Cancer Driver No 66 0.119 12 0 0.0 0
PHKG1_ENST00000297373 PHKG1 Q16816 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform chr7 GO:0005524 Not Cancer Driver No 58 0.15 23 4 0.174 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 GO:0005524 Not Cancer Driver No 48 0.118 50 6 0.12 4
PI4K2A PI4K2A Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha chr10 GO:0005524 Not Cancer Driver No 43 0.09 129 6 0.047 0
PI4K2B PI4K2B Q8TCG2 Phosphatidylinositol 4-kinase type 2-beta chr4 GO:0005524 Not Cancer Driver No 51 0.106 99 4 0.04 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 GO:0005524 Not Cancer Driver No 267 0.127 142 11 0.077 1
PI4KB_ENST00000368873 PI4KB Q9UBF8 Phosphatidylinositol 4-kinase beta chr1 GO:0005524 Not Cancer Driver No 93 0.114 311 34 0.109 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0005524 Not Cancer Driver No 54 0.084 209 11 0.053 0
PIK3C2A PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 GO:0005524 Not Cancer Driver No 187 0.111 350 43 0.123 0
PIK3C2B PIK3C2B O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta chr1 GO:0005524 Not Cancer Driver No 241 0.147 425 71 0.167 0
PIK3C2G_ENST00000433979 PIK3C2G O75747 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma chr12 GO:0005524 Not Cancer Driver No 283 0.196 211 37 0.175 0
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0005524 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0005524 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0005524 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0005524 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0005524 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0005524 Not Cancer Driver No 193 0.142 315 45 0.143 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0005524 Not Cancer Driver No 278 0.133 848 101 0.119 1
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0005524 Census, Compendium Yes 71 0.227 27 8 0.296 0
PIM2 PIM2 Q9P1W9 Serine/threonine-protein kinase pim-2 chrX GO:0005524 Not Cancer Driver No 43 0.138 47 10 0.213 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0005524 Not Cancer Driver No 24 0.074 9 0 0.0 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0005524 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0005524 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0005524 Not Cancer Driver No 62 0.147 111 23 0.207 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0005524 Not Cancer Driver No 74 0.132 216 29 0.134 0
PIP5K1B PIP5K1B O14986 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta chr9 GO:0005524 Not Cancer Driver No 94 0.174 162 36 0.222 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0005524 Not Cancer Driver No 98 0.147 360 60 0.167 1
PIP5KL1 PIP5KL1 Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 chr9 GO:0005524 Not Cancer Driver No 28 0.071 74 6 0.081 0
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0005524 Not Cancer Driver No 36 0.073 124 0 0.0 0
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0005524 Not Cancer Driver No 112 0.195 26 5 0.192 101
PKMYT1 PKMYT1 Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase chr16 GO:0005524 Not Cancer Driver No 39 0.078 228 19 0.083 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0005524 Not Cancer Driver No 78 0.147 58 13 0.224 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0005524 Not Cancer Driver No 120 0.127 459 54 0.118 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 GO:0005524 Not Cancer Driver No 123 0.125 415 48 0.116 0
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 GO:0005524 Not Cancer Driver No 99 0.111 392 49 0.125 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0005524 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0005524 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0005524 Not Cancer Driver No 75 0.116 202 15 0.074 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 GO:0005524 Not Cancer Driver No 102 0.105 451 45 0.1 0
PLK5 PLK5 Q496M5 Inactive serine/threonine-protein kinase PLK5 chr19 GO:0005524 Not Cancer Driver No 8 0.024 215 4 0.019 0
PMS1 PMS1 P54277 PMS1 protein homolog 1 chr2 GO:0005524 Census Yes 114 0.122 283 38 0.134 0
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 GO:0005524 Census, Compendium Yes 117 0.136 331 44 0.133 9
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 GO:0005524 Not Cancer Driver No 38 0.198 3 0 0.0 0
PNCK_ENST00000370150 PNCK Q6P2M8 Calcium/calmodulin-dependent protein kinase type 1B chrX GO:0005524 Not Cancer Driver No 55 0.16 30 4 0.133 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0005524 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0005524 Not Cancer Driver No 94 0.12 140 18 0.129 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0005524 Census, Compendium Yes 364 0.141 949 135 0.142 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 GO:0005524 Not Cancer Driver No 53 0.151 30 9 0.3 3
PPCS PPCS Q9HAB8 Phosphopantothenate--cysteine ligase chr1 GO:0005524 Not Cancer Driver No 39 0.125 13 0 0.0 2
PPIP5K1 PPIP5K1 Q6PFW1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 chr15 GO:0005524 Not Cancer Driver No 58 0.04 544 25 0.046 0
PPIP5K2_ENST00000358359 PPIP5K2 O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 chr5 GO:0005524 Not Cancer Driver No 146 0.117 419 54 0.129 1
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 GO:0005524 Not Cancer Driver No 70 0.14 73 12 0.164 0
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:0005524 Not Cancer Driver No 193 0.137 988 150 0.152 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0005524 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0005524 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0005524 Census Yes 53 0.151 24 0 0.0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 GO:0005524 Not Cancer Driver No 50 0.142 26 6 0.231 4
PRKACG PRKACG P22612 cAMP-dependent protein kinase catalytic subunit gamma chr9 GO:0005524 Not Cancer Driver No 74 0.211 23 7 0.304 1
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0005524 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0005524 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:0005524 Not Cancer Driver No 74 0.151 144 25 0.174 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0005524 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0005524 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0005524 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0005524 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0005524 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0005524 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0005524 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0005524 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0005524 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0005524 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0005524 Compendium Yes 118 0.134 246 34 0.138 0
PRKD3 PRKD3 O94806 Serine/threonine-protein kinase D3 chr2 GO:0005524 Not Cancer Driver No 125 0.14 183 20 0.109 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0005524 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 GO:0005524 Not Cancer Driver No 167 0.249 93 22 0.237 1
PRKG2 PRKG2 Q13237 cGMP-dependent protein kinase 2 chr4 GO:0005524 Not Cancer Driver No 138 0.181 217 48 0.221 0
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX GO:0005524 Not Cancer Driver No 54 0.151 69 3 0.043 0
PRPF4B PRPF4B Q13523 Serine/threonine-protein kinase PRP4 homolog chr6 GO:0005524 Not Cancer Driver No 120 0.119 646 86 0.133 0
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:0005524 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS1L1_ENST00000638645 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:0005524 Not Cancer Driver No 83 0.261 0 0 0.0 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:0005524 Not Cancer Driver No 56 0.176 4 1 0.25 0
PSKH1 PSKH1 P11801 Serine/threonine-protein kinase H1 chr16 GO:0005524 Not Cancer Driver No 56 0.132 122 24 0.197 0
PSKH2 PSKH2 Q96QS6 Serine/threonine-protein kinase H2 chr8 GO:0005524 Not Cancer Driver No 86 0.223 87 19 0.218 0
PSMC1 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 GO:0005524 Not Cancer Driver No 36 0.082 165 10 0.061 0
PSMC2_ENST00000292644 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 GO:0005524 Not Cancer Driver No 63 0.145 120 13 0.108 0
PSMC3_ENST00000298852 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 GO:0005524 Not Cancer Driver No 55 0.125 131 10 0.076 0
PSMC4 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 GO:0005524 Not Cancer Driver No 51 0.122 21 3 0.143 0
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 GO:0005524 Not Cancer Driver No 52 0.128 64 6 0.094 0
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 GO:0005524 Not Cancer Driver No 49 0.126 69 8 0.116 0
PSTK PSTK Q8IV42 L-seryl-tRNA(Sec) kinase chr10 GO:0005524 Not Cancer Driver No 48 0.138 79 15 0.19 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0005524 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0005524 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0005524 Census Yes 42 0.093 12 0 0.0 0
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0005524 Not Cancer Driver No 153 0.143 359 58 0.162 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0005524 Not Cancer Driver No 40 0.112 63 2 0.032 0
PXK PXK Q7Z7A4 PX domain-containing protein kinase-like protein chr3 GO:0005524 Not Cancer Driver No 71 0.123 169 18 0.107 0
PYGL PYGL P06737 Glycogen phosphorylase, liver form chr14 GO:0005524 Not Cancer Driver No 98 0.116 23 2 0.087 2
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0005524 Not Cancer Driver No 101 0.13 106 16 0.151 4
QRSL1 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 GO:0005524 Not Cancer Driver No 63 0.119 63 4 0.063 2
RAD17 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 GO:0005524 Census Yes 78 0.115 207 19 0.092 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0005524 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0005524 Census Yes 45 0.117 13 0 0.0 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0005524 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0005524 Not Cancer Driver No 34 0.104 49 10 0.204 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0005524 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD54B RAD54B Q9Y620 DNA repair and recombination protein RAD54B chr8 GO:0005524 Not Cancer Driver No 112 0.123 120 16 0.133 0
RAD54L2 RAD54L2 Q9Y4B4 Helicase ARIP4 chr3 GO:0005524 Not Cancer Driver No 194 0.132 753 97 0.129 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0005524 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0005524 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:0005524 Not Cancer Driver No 65 0.099 381 46 0.121 0
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 GO:0005524 Not Cancer Driver No 72 0.109 41 3 0.073 2
RARS2 RARS2 Q5T160 Probable arginine--tRNA ligase, mitochondrial chr6 GO:0005524 Not Cancer Driver No 88 0.152 20 1 0.05 0
RBKS RBKS Q9H477 Ribokinase chr2 GO:0005524 Not Cancer Driver No 27 0.084 28 5 0.179 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0005524 Census, Compendium Yes 138 0.114 608 71 0.117 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0005524 Not Cancer Driver No 132 0.133 495 71 0.143 0
RECQL_ENST00000421138 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 GO:0005524 Not Cancer Driver No 67 0.103 91 5 0.055 0
RENBP RENBP P51606 N-acylglucosamine 2-epimerase chrX GO:0005524 Not Cancer Driver No 65 0.152 64 10 0.156 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0005524 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0005524 Not Cancer Driver No 147 0.128 674 82 0.122 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0005524 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0005524 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0005524 Not Cancer Driver No 38 0.112 20 1 0.05 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0005524 Not Cancer Driver No 15 0.097 1 0 0.0 0
RHOBTB3 RHOBTB3 O94955 Rho-related BTB domain-containing protein 3 chr5 GO:0005524 Not Cancer Driver No 67 0.11 34 2 0.059 0
RIMKLA RIMKLA Q8IXN7 N-acetylaspartylglutamate synthase A chr1 GO:0005524 Not Cancer Driver No 65 0.166 71 17 0.239 0
RIMKLB RIMKLB Q9ULI2 Beta-citrylglutamate synthase B chr12 GO:0005524 Not Cancer Driver No 62 0.161 46 3 0.065 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 GO:0005524 Not Cancer Driver No 69 0.121 301 37 0.123 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 GO:0005524 Not Cancer Driver No 68 0.123 253 33 0.13 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0005524 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0005524 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0005524 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0005524 Not Cancer Driver No 66 0.127 295 39 0.132 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 GO:0005524 Not Cancer Driver No 119 0.143 232 34 0.147 3
RNASEL RNASEL Q05823 2-5A-dependent ribonuclease chr1 GO:0005524 Not Cancer Driver No 95 0.128 147 17 0.116 0
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 GO:0005524 Not Cancer Driver No 69 0.116 112 12 0.107 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0005524 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0005524 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:0005524 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0005524 Not Cancer Driver No 203 0.215 299 71 0.237 5
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 GO:0005524 Census Yes 498 0.212 191 55 0.288 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0005524 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0005524 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0005524 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0005524 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0005524 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0005524 Not Cancer Driver No 180 0.242 136 36 0.265 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0005524 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 GO:0005524 Not Cancer Driver No 54 0.112 194 16 0.082 0
RPS6KC1 RPS6KC1 Q96S38 Ribosomal protein S6 kinase delta-1 chr1 GO:0005524 Not Cancer Driver No 158 0.148 475 62 0.131 0
RPS6KL1_ENST00000557413 RPS6KL1 Q9Y6S9 Ribosomal protein S6 kinase-like 1 chr14 GO:0005524 Not Cancer Driver No 60 0.109 161 16 0.099 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:0005524 Not Cancer Driver No 74 0.093 41 7 0.171 0
RTCA_ENST00000370128 RTCA O00442 RNA 3'-terminal phosphate cyclase chr1 GO:0005524 Not Cancer Driver No 35 0.096 36 1 0.028 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0005524 Not Cancer Driver No 144 0.118 474 64 0.135 14
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0005524 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0005524 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0005524 Not Cancer Driver No 59 0.142 331 45 0.136 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0005524 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0005524 Not Cancer Driver No 62 0.134 100 13 0.13 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0005524 Not Cancer Driver No 55 0.091 85 4 0.047 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0005524 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
SARS2_ENST00000221431 SARS2 Q9NP81 Serine--tRNA ligase, mitochondrial chr19 GO:0005524 Not Cancer Driver No 64 0.124 111 14 0.126 1
SARS_ENST00000234677 SARS1 P49591 Serine--tRNA ligase, cytoplasmic chr1 GO:0005524 Not Cancer Driver No 56 0.109 83 4 0.048 1
SBK1 SBK1 Q52WX2 Serine/threonine-protein kinase SBK1 chr16 GO:0005524 Not Cancer Driver No 41 0.097 139 6 0.043 0
SBK2_ENST00000344158 SBK2 P0C263 Serine/threonine-protein kinase SBK2 chr19 GO:0005524 Not Cancer Driver No 67 0.193 73 13 0.178 0
SBK3 SBK3 P0C264 Uncharacterized serine/threonine-protein kinase SBK3 chr19 GO:0005524 Not Cancer Driver No 1 0.003 157 0 0.0 0
SCN8A SCN8A Q9UQD0 Sodium channel protein type 8 subunit alpha chr12 GO:0005524 Not Cancer Driver No 290 0.146 460 75 0.163 28
SCYL1 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 GO:0005524 Not Cancer Driver No 85 0.105 312 32 0.103 0
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 GO:0005524 Not Cancer Driver No 103 0.111 328 29 0.088 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 GO:0005524 Not Cancer Driver No 81 0.109 249 28 0.112 0
SELENOO SELENOO Q9BVL4 Protein adenylyltransferase SelO, mitochondrial chr22 GO:0005524 Not Cancer Driver No 57 0.085 129 6 0.047 0
SEPHS1 SEPHS1 P49903 Selenide, water dikinase 1 chr10 GO:0005524 Not Cancer Driver No 58 0.148 29 10 0.345 0
SEPHS2 SEPHS2 Q99611 Selenide, water dikinase 2 chr16 GO:0005524 Not Cancer Driver No 48 0.107 104 2 0.019 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0005524 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0005524 Census, Compendium Yes 58 0.135 86 16 0.186 0
SGK2_ENST00000373100 SGK2 Q9HBY8 Serine/threonine-protein kinase Sgk2 chr20 GO:0005524 Not Cancer Driver No 84 0.229 52 10 0.192 0
SGK3_ENST00000521198 SGK3 Q96BR1 Serine/threonine-protein kinase Sgk3 chr8 GO:0005524 Not Cancer Driver No 54 0.109 70 10 0.143 0
SGK494 RSKR Q96LW2 Ribosomal protein S6 kinase-related protein chr17 GO:0005524 Not Cancer Driver No 39 0.095 47 4 0.085 0
SHPK SHPK Q9UHJ6 Sedoheptulokinase chr17 GO:0005524 Not Cancer Driver No 44 0.092 31 1 0.032 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0005524 Not Cancer Driver No 227 0.135 359 51 0.142 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0005524 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 GO:0005524 Not Cancer Driver No 94 0.102 525 56 0.107 0
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 GO:0005524 Not Cancer Driver No 143 0.108 964 107 0.111 1
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0005524 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLC22A4 SLC22A4 Q9H015 Solute carrier family 22 member 4 chr5 GO:0005524 Not Cancer Driver No 57 0.103 8 2 0.25 0
SLC22A5_ENST00000245407 SLC22A5 O76082 Solute carrier family 22 member 5 chr5 GO:0005524 Not Cancer Driver No 53 0.095 15 2 0.133 73
SLC27A2 SLC27A2 O14975 Very long-chain acyl-CoA synthetase chr15 GO:0005524 Not Cancer Driver No 95 0.153 4 0 0.0 0
SLC27A5 SLC27A5 Q9Y2P5 Bile acyl-CoA synthetase chr19 GO:0005524 Not Cancer Driver No 107 0.155 7 2 0.286 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0005524 Not Cancer Driver No 177 0.196 34 8 0.235 0
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0005524 Not Cancer Driver No 152 0.169 45 5 0.111 0
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0005524 Not Cancer Driver No 66 0.072 61 3 0.049 4
SLFN5 SLFN5 Q08AF3 Schlafen family member 5 chr17 GO:0005524 Not Cancer Driver No 122 0.137 61 11 0.18 0
SLFNL1_ENST00000302946 SLFNL1 Q499Z3 Schlafen-like protein 1 chr1 GO:0005524 Not Cancer Driver No 60 0.147 133 17 0.128 0
SLK SLK Q9H2G2 STE20-like serine/threonine-protein kinase chr10 GO:0005524 Not Cancer Driver No 134 0.109 962 96 0.1 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:0005524 Compendium Yes 143 0.136 309 41 0.133 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 GO:0005524 Not Cancer Driver No 273 0.172 1009 160 0.159 42
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0005524 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0005524 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCAD1_ENST00000354268 SMARCAD1 Q9H4L7 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 chr4 GO:0005524 Not Cancer Driver No 129 0.126 388 50 0.129 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0005524 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0005524 Census, Compendium Yes 200 0.162 717 114 0.159 21
SMC1B SMC1B Q8NDV3 Structural maintenance of chromosomes protein 1B chr22 GO:0005524 Not Cancer Driver No 174 0.141 332 48 0.145 0
SMC2 SMC2 O95347 Structural maintenance of chromosomes protein 2 chr9 GO:0005524 Not Cancer Driver No 145 0.121 573 88 0.154 0
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0005524 Not Cancer Driver No 149 0.122 605 70 0.116 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 GO:0005524 Not Cancer Driver No 175 0.136 539 55 0.102 0
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0005524 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0005524 Not Cancer Driver No 128 0.117 458 57 0.124 0
SMCHD1 SMCHD1 A6NHR9 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 chr18 GO:0005524 Not Cancer Driver No 240 0.12 342 45 0.132 45
SMG1 SMG1 Q96Q15 Serine/threonine-protein kinase SMG1 chr16 GO:0005524 Not Cancer Driver No 348 0.095 605 73 0.121 0
SNRK SNRK Q9NRH2 SNF-related serine/threonine-protein kinase chr3 GO:0005524 Not Cancer Driver No 82 0.107 368 47 0.128 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 GO:0005524 Not Cancer Driver No 237 0.111 270 37 0.137 11
SPAST SPAST Q9UBP0 Spastin chr2 GO:0005524 Not Cancer Driver No 73 0.119 270 25 0.093 77
SPATA5 SPATA5 Q8NB90 ATPase family protein 2 homolog chr4 GO:0005524 Not Cancer Driver No 101 0.113 165 16 0.097 10
SPATA5L1 SPATA5L1 Q9BVQ7 Spermatogenesis-associated protein 5-like protein 1 chr15 GO:0005524 Not Cancer Driver No 62 0.082 166 13 0.078 0
SPEG SPEG Q15772 Striated muscle preferentially expressed protein kinase chr2 GO:0005524 Not Cancer Driver No 405 0.124 2004 219 0.109 1
SPG7 SPG7 Q9UQ90 Paraplegin chr16 GO:0005524 Not Cancer Driver No 97 0.122 181 29 0.16 4
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0005524 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0005524 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0005524 Not Cancer Driver No 59 0.149 26 5 0.192 0
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 GO:0005524 Not Cancer Driver No 438 0.136 2534 340 0.134 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0005524 Census Yes 53 0.099 130 11 0.085 1
SRMS SRMS Q9H3Y6 Tyrosine-protein kinase Srms chr20 GO:0005524 Not Cancer Driver No 77 0.158 48 11 0.229 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 GO:0005524 Not Cancer Driver No 73 0.111 329 32 0.097 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0005524 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRPK3 SRPK3 Q9UPE1 SRSF protein kinase 3 chrX GO:0005524 Not Cancer Driver No 63 0.111 217 30 0.138 0
SRR SRR Q9GZT4 Serine racemase chr17 GO:0005524 Not Cancer Driver No 40 0.118 32 6 0.188 0
SRXN1 SRXN1 Q9BYN0 Sulfiredoxin-1 chr20 GO:0005524 Not Cancer Driver No 15 0.109 48 2 0.042 0
STARD9 STARD9 Q9P2P6 StAR-related lipid transfer protein 9 chr15 GO:0005524 Not Cancer Driver No 104 0.022 3390 76 0.022 0
STK10 STK10 O94804 Serine/threonine-protein kinase 10 chr5 GO:0005524 Not Cancer Driver No 120 0.124 666 86 0.129 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0005524 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK16_ENST00000396738 STK16 O75716 Serine/threonine-protein kinase 16 chr2 GO:0005524 Not Cancer Driver No 42 0.138 48 3 0.062 0
STK17A STK17A Q9UEE5 Serine/threonine-protein kinase 17A chr7 GO:0005524 Not Cancer Driver No 44 0.106 115 16 0.139 0
STK17B_ENST00000409228 STK17B O94768 Serine/threonine-protein kinase 17B chr2 GO:0005524 Not Cancer Driver No 57 0.153 60 12 0.2 0
STK19 STK19 P49842 Serine/threonine-protein kinase 19 chr6 GO:0005524 Not Cancer Driver No 60 0.163 129 28 0.217 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0005524 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 GO:0005524 Not Cancer Driver No 42 0.099 170 15 0.088 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0005524 Not Cancer Driver No 62 0.149 119 18 0.151 0
STK31 STK31 Q9BXU1 Serine/threonine-protein kinase 31 chr7 GO:0005524 Not Cancer Driver No 248 0.243 98 18 0.184 0
STK32A_ENST00000397936 STK32A Q8WU08 Serine/threonine-protein kinase 32A chr5 GO:0005524 Not Cancer Driver No 48 0.121 74 10 0.135 0
STK32B STK32B Q9NY57 Serine/threonine-protein kinase 32B chr4 GO:0005524 Not Cancer Driver No 96 0.232 72 14 0.194 0
STK32C STK32C Q86UX6 Serine/threonine-protein kinase 32C chr10 GO:0005524 Not Cancer Driver No 49 0.101 172 10 0.058 0
STK33_ENST00000315204 STK33 Q9BYT3 Serine/threonine-protein kinase 33 chr11 GO:0005524 Not Cancer Driver No 98 0.191 215 43 0.2 0
STK35 STK35 Q8TDR2 Serine/threonine-protein kinase 35 chr20 GO:0005524 Not Cancer Driver No 41 0.077 236 13 0.055 0
STK36_ENST00000440309 STK36 Q9NRP7 Serine/threonine-protein kinase 36 chr2 GO:0005524 Not Cancer Driver No 167 0.127 250 36 0.144 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 GO:0005524 Not Cancer Driver No 57 0.123 77 6 0.078 0
STK38L STK38L Q9Y2H1 Serine/threonine-protein kinase 38-like chr12 GO:0005524 Not Cancer Driver No 51 0.11 86 12 0.14 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0005524 Not Cancer Driver No 64 0.117 182 19 0.104 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0005524 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0005524 Not Cancer Driver No 70 0.144 231 30 0.13 0
STK40_ENST00000373132 STK40 Q8N2I9 Serine/threonine-protein kinase 40 chr1 GO:0005524 Not Cancer Driver No 50 0.115 103 9 0.087 0
STKLD1 STKLD1 Q8NE28 Serine/threonine kinase-like domain-containing protein STKLD1 chr9 GO:0005524 Not Cancer Driver No 101 0.149 59 9 0.153 0
STRADA STRADA Q7RTN6 STE20-related kinase adapter protein alpha chr17 GO:0005524 Not Cancer Driver No 49 0.114 118 14 0.119 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 GO:0005524 Not Cancer Driver No 53 0.127 84 7 0.083 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 GO:0005524 Not Cancer Driver No 83 0.197 35 10 0.286 0
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 GO:0005524 Not Cancer Driver No 51 0.11 46 6 0.13 3
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 GO:0005524 Not Cancer Driver No 48 0.111 12 2 0.167 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0005524 Not Cancer Driver No 72 0.092 140 12 0.086 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0005524 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0005524 Census Yes 96 0.151 131 27 0.206 5
SYN1 SYN1 P17600 Synapsin-1 chrX GO:0005524 Not Cancer Driver No 75 0.106 445 27 0.061 0
SYN2 SYN2 Q92777 Synapsin-2 chr3 GO:0005524 Not Cancer Driver No 56 0.096 295 21 0.071 0
SYN3 SYN3 O14994 Synapsin-3 chr22 GO:0005524 Not Cancer Driver No 94 0.162 292 47 0.161 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0005524 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0005524 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0005524 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0005524 Not Cancer Driver No 123 0.137 494 64 0.13 0
TAP2 TAP2 Q03519 Antigen peptide transporter 2 chr6 GO:0005524 Not Cancer Driver No 71 0.103 20 1 0.05 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 GO:0005524 Not Cancer Driver No 112 0.156 53 10 0.189 1
TARSL2 TARS3 A2RTX5 Threonine--tRNA ligase 2, cytoplasmic chr15 GO:0005524 Not Cancer Driver No 90 0.112 77 14 0.182 0
TARS_ENST00000265112 TARS1 P26639 Threonine--tRNA ligase 1, cytoplasmic chr5 GO:0005524 Not Cancer Driver No 112 0.155 112 22 0.196 2
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0005524 Not Cancer Driver No 115 0.129 88 9 0.102 2
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0005524 Not Cancer Driver No 101 0.139 42 5 0.119 12
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0005524 Not Cancer Driver No 54 0.097 55 10 0.182 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0005524 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDRD12_ENST00000444215 TDRD12 Q587J7 Putative ATP-dependent RNA helicase TDRD12 chr19 GO:0005524 Not Cancer Driver No 36 0.031 220 10 0.045 0
TDRD9 TDRD9 Q8NDG6 ATP-dependent RNA helicase TDRD9 chr14 GO:0005524 Not Cancer Driver No 156 0.113 108 0 0.0 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 GO:0005524 Census, Compendium Yes 91 0.144 57 15 0.263 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0005524 Not Cancer Driver No 219 0.195 126 22 0.175 10
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0005524 Not Cancer Driver No 65 0.134 75 15 0.2 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0005524 Not Cancer Driver No 106 0.137 442 43 0.097 0
TEP1 TEP1 Q99973 Telomerase protein component 1 chr14 GO:0005524 Not Cancer Driver No 332 0.126 396 67 0.169 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0005524 Not Cancer Driver No 63 0.101 339 35 0.103 0
TESK2 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 GO:0005524 Not Cancer Driver No 77 0.135 242 43 0.178 0
TEX14 TEX14 Q8IWB6 Inactive serine/threonine-protein kinase TEX14 chr17 GO:0005524 Not Cancer Driver No 214 0.143 872 115 0.132 0
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0005524 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0005524 Census, Compendium Yes 106 0.187 60 16 0.267 25
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0005524 Not Cancer Driver No 32 0.107 22 2 0.091 1
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 GO:0005524 Census Yes 137 0.143 955 137 0.143 0
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 GO:0005524 Not Cancer Driver No 200 0.176 223 46 0.206 0
TIMM44 TIMM44 O43615 Mitochondrial import inner membrane translocase subunit TIM44 chr19 GO:0005524 Not Cancer Driver No 56 0.124 175 22 0.126 0
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 GO:0005524 Not Cancer Driver No 26 0.111 13 4 0.308 0
TK2 TK2 O00142 Thymidine kinase 2, mitochondrial chr16 GO:0005524 Not Cancer Driver No 23 0.087 44 3 0.068 11
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:0005524 Not Cancer Driver No 66 0.115 91 14 0.154 2
TLK1 TLK1 Q9UKI8 Serine/threonine-protein kinase tousled-like 1 chr2 GO:0005524 Not Cancer Driver No 103 0.134 388 53 0.137 0
TLK2 TLK2 Q86UE8 Serine/threonine-protein kinase tousled-like 2 chr17 GO:0005524 Not Cancer Driver No 120 0.155 436 58 0.133 5
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 GO:0005524 Not Cancer Driver No 254 0.187 781 156 0.2 0
TNK1 TNK1 Q13470 Non-receptor tyrosine-protein kinase TNK1 chr17 GO:0005524 Not Cancer Driver No 51 0.077 298 24 0.081 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 GO:0005524 Not Cancer Driver No 137 0.132 593 81 0.137 0
TNNI3K TNNI3K Q59H18 Serine/threonine-protein kinase TNNI3K chr1 GO:0005524 Not Cancer Driver No 234 0.28 78 26 0.333 1
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 GO:0005524 Census, Compendium Yes 93 0.122 391 53 0.136 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0005524 Compendium Yes 150 0.098 508 59 0.116 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0005524 Not Cancer Driver No 154 0.095 543 46 0.085 0
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0005524 Not Cancer Driver No 33 0.099 0 0 0.0 3
TOR1B TOR1B O14657 Torsin-1B chr9 GO:0005524 Not Cancer Driver No 36 0.107 0 0 0.0 0
TOR3A TOR3A Q9H497 Torsin-3A chr1 GO:0005524 Not Cancer Driver No 50 0.126 15 0 0.0 0
TOR4A TOR4A Q9NXH8 Torsin-4A chr9 GO:0005524 Not Cancer Driver No 27 0.064 103 2 0.019 0
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 GO:0005524 Not Cancer Driver No 20 0.079 51 2 0.039 3
TPK1 TPK1 Q9H3S4 Thiamin pyrophosphokinase 1 chr7 GO:0005524 Not Cancer Driver No 56 0.23 0 0 0.0 3
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:0005524 Not Cancer Driver No 74 0.105 110 11 0.1 0
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0005524 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0005524 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIO TRIO O75962 Triple functional domain protein chr5 GO:0005524 Not Cancer Driver No 400 0.129 1052 118 0.112 10
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 GO:0005524 Not Cancer Driver No 62 0.144 30 6 0.2 1
TRIT1 TRIT1 Q9H3H1 tRNA dimethylallyltransferase chr1 GO:0005524 Not Cancer Driver No 61 0.131 121 19 0.157 1
TRMU TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 GO:0005524 Not Cancer Driver No 40 0.095 28 5 0.179 2
TRNT1 TRNT1 Q96Q11 CCA tRNA nucleotidyltransferase 1, mitochondrial chr3 GO:0005524 Not Cancer Driver No 60 0.138 49 8 0.163 7
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0005524 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPM6 TRPM6 Q9BX84 Transient receptor potential cation channel subfamily M member 6 chr9 GO:0005524 Not Cancer Driver No 431 0.213 458 99 0.216 6
TRPM7 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 GO:0005524 Not Cancer Driver No 199 0.107 455 60 0.132 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0005524 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0005524 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSSK1B TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 GO:0005524 Not Cancer Driver No 104 0.283 114 36 0.316 0
TSSK2 TSSK2 Q96PF2 Testis-specific serine/threonine-protein kinase 2 chr22 GO:0005524 Not Cancer Driver No 50 0.14 91 11 0.121 0
TSSK3 TSSK3 Q96PN8 Testis-specific serine/threonine-protein kinase 3 chr1 GO:0005524 Not Cancer Driver No 30 0.112 0 0 0.0 0
TSSK4_ENST00000287913 TSSK4 Q6SA08 Testis-specific serine/threonine-protein kinase 4 chr14 GO:0005524 Not Cancer Driver No 29 0.088 8 1 0.125 0
TSSK6 TSSK6 Q9BXA6 Testis-specific serine/threonine-protein kinase 6 chr19 GO:0005524 Not Cancer Driver No 47 0.172 0 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0005524 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTBK2 TTBK2 Q6IQ55 Tau-tubulin kinase 2 chr15 GO:0005524 Not Cancer Driver No 151 0.121 848 107 0.126 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0005524 Not Cancer Driver No 118 0.102 550 50 0.091 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0005524 Not Cancer Driver No 136 0.159 352 46 0.131 0
TTL TTL Q8NG68 Tubulin--tyrosine ligase chr2 GO:0005524 Not Cancer Driver No 37 0.098 24 0 0.0 0
TTLL1 TTLL1 O95922 Polyglutamylase complex subunit TTLL1 chr22 GO:0005524 Not Cancer Driver No 69 0.163 48 9 0.188 0
TTLL10_ENST00000379289 TTLL10 Q6ZVT0 Inactive polyglycylase TTLL10 chr1 GO:0005524 Not Cancer Driver No 64 0.095 314 22 0.07 0
TTLL11 TTLL11 Q8NHH1 Tubulin polyglutamylase TTLL11 chr9 GO:0005524 Not Cancer Driver No 85 0.106 275 20 0.073 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 GO:0005524 Not Cancer Driver No 69 0.107 100 6 0.06 0
TTLL13P TTLL13 A6NNM8 Tubulin polyglutamylase TTLL13 chr15 GO:0005524 Not Cancer Driver No 78 0.096 310 20 0.065 0
TTLL2 TTLL2 Q9BWV7 Probable tubulin polyglutamylase TTLL2 chr6 GO:0005524 Not Cancer Driver No 103 0.174 239 40 0.167 0
TTLL4_ENST00000258398 TTLL4 Q14679 Tubulin monoglutamylase TTLL4 chr2 GO:0005524 Not Cancer Driver No 147 0.123 478 58 0.121 0
TTLL5 TTLL5 Q6EMB2 Tubulin polyglutamylase TTLL5 chr14 GO:0005524 Not Cancer Driver No 165 0.129 692 82 0.118 1
TTLL7 TTLL7 Q6ZT98 Tubulin polyglutamylase TTLL7 chr1 GO:0005524 Not Cancer Driver No 169 0.191 330 68 0.206 0
TTLL9_ENST00000375938 TTLL9 Q3SXZ7 Probable tubulin polyglutamylase TTLL9 chr20 GO:0005524 Not Cancer Driver No 88 0.2 73 11 0.151 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 GO:0005524 Not Cancer Driver No 7917 0.23 12926 2861 0.221 10
TUT1_ENST00000476907 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 GO:0005524 Not Cancer Driver No 97 0.111 410 50 0.122 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0005524 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0005524 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0005524 Not Cancer Driver No 95 0.139 135 11 0.081 38
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0005524 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0005524 Not Cancer Driver No 148 0.125 213 29 0.136 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0005524 Not Cancer Driver No 119 0.134 197 17 0.086 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX GO:0005524 Not Cancer Driver No 117 0.111 165 22 0.133 6
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 GO:0005524 Not Cancer Driver No 84 0.131 219 33 0.151 0
UBA3 UBA3 Q8TBC4 NEDD8-activating enzyme E1 catalytic subunit chr3 GO:0005524 Not Cancer Driver No 48 0.104 44 4 0.091 0
UBA5 UBA5 Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 chr3 GO:0005524 Not Cancer Driver No 41 0.101 126 8 0.063 7
UBA6 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 GO:0005524 Not Cancer Driver No 133 0.126 90 10 0.111 0
UBA7 UBA7 P41226 Ubiquitin-like modifier-activating enzyme 7 chr3 GO:0005524 Not Cancer Driver No 92 0.091 166 15 0.09 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0005524 Compendium Yes 35 0.23 67 13 0.194 2
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0005524 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0005524 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 GO:0005524 Not Cancer Driver No 13 0.088 14 0 0.0 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 GO:0005524 Compendium Yes 19 0.129 13 1 0.077 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0005524 Not Cancer Driver No 21 0.143 13 4 0.308 0
UBE2D4 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 GO:0005524 Not Cancer Driver No 13 0.088 21 1 0.048 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 GO:0005524 Not Cancer Driver No 21 0.109 78 10 0.128 0
UBE2E2_ENST00000425792 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 GO:0005524 Not Cancer Driver No 28 0.139 90 15 0.167 0
UBE2E3_ENST00000602710 UBE2E3 Q969T4 Ubiquitin-conjugating enzyme E2 E3 chr2 GO:0005524 Not Cancer Driver No 34 0.164 97 14 0.144 0
UBE2F_ENST00000272930 UBE2F Q969M7 NEDD8-conjugating enzyme UBE2F chr2 GO:0005524 Not Cancer Driver No 21 0.114 19 5 0.263 0
UBE2G1 UBE2G1 P62253 Ubiquitin-conjugating enzyme E2 G1 chr17 GO:0005524 Not Cancer Driver No 9 0.053 39 2 0.051 0
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0005524 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2H UBE2H P62256 Ubiquitin-conjugating enzyme E2 H chr7 GO:0005524 Not Cancer Driver No 20 0.109 55 11 0.2 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0005524 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2J1 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 GO:0005524 Not Cancer Driver No 33 0.104 158 20 0.127 0
UBE2J2_ENST00000349431 UBE2J2 Q8N2K1 Ubiquitin-conjugating enzyme E2 J2 chr1 GO:0005524 Not Cancer Driver No 42 0.162 51 7 0.137 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0005524 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0005524 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2L5_ENST00000436446 UBE2L5 A0A1B0GUS4 Ubiquitin-conjugating enzyme E2 L5 chr13 GO:0005524 Not Cancer Driver No 1 0.006 42 0 0.0 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 GO:0005524 Not Cancer Driver No 30 0.164 32 6 0.188 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0005524 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 GO:0005524 Not Cancer Driver No 129 0.1 716 68 0.095 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 GO:0005524 Not Cancer Driver No 45 0.107 173 16 0.092 0
UBE2Q2 UBE2Q2 Q8WVN8 Ubiquitin-conjugating enzyme E2 Q2 chr15 GO:0005524 Not Cancer Driver No 35 0.093 122 10 0.082 0
UBE2QL1 UBE2QL1 A1L167 Ubiquitin-conjugating enzyme E2Q-like protein 1 chr5 GO:0005524 Not Cancer Driver No 16 0.099 4 0 0.0 0
UBE2R2 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 GO:0005524 Not Cancer Driver No 28 0.118 104 15 0.144 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0005524 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE2T UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 GO:0005524 Not Cancer Driver No 12 0.061 97 9 0.093 1
UBE2U_ENST00000611228 UBE2U Q5VVX9 Ubiquitin-conjugating enzyme E2 U chr1 GO:0005524 Not Cancer Driver No 38 0.118 66 1 0.015 0
UBE2W_ENST00000602593 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 GO:0005524 Not Cancer Driver No 19 0.126 26 5 0.192 0
UBE2Z UBE2Z Q9H832 Ubiquitin-conjugating enzyme E2 Z chr17 GO:0005524 Not Cancer Driver No 27 0.076 140 10 0.071 0
UCK1_ENST00000372215 UCK1 Q9HA47 Uridine-cytidine kinase 1 chr9 GO:0005524 Not Cancer Driver No 35 0.126 70 3 0.043 0
UCK2 UCK2 Q9BZX2 Uridine-cytidine kinase 2 chr1 GO:0005524 Not Cancer Driver No 43 0.165 61 10 0.164 0
UCKL1 UCKL1 Q9NWZ5 Uridine-cytidine kinase-like 1 chr20 GO:0005524 Not Cancer Driver No 54 0.099 134 15 0.112 0
UHMK1 UHMK1 Q8TAS1 Serine/threonine-protein kinase Kist chr1 GO:0005524 Not Cancer Driver No 42 0.1 14 2 0.143 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0005524 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0005524 Not Cancer Driver No 132 0.127 519 84 0.162 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 GO:0005524 Not Cancer Driver No 37 0.078 55 2 0.036 0
ULK4 ULK4 Q96C45 Serine/threonine-protein kinase ULK4 chr3 GO:0005524 Not Cancer Driver No 162 0.127 180 33 0.183 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0005524 Not Cancer Driver No 146 0.129 329 36 0.109 0
VARS VARS1 P26640 Valine--tRNA ligase chr6 GO:0005524 Not Cancer Driver No 145 0.115 251 26 0.104 0
VARS2_ENST00000321897 VARS2 Q5ST30 Valine--tRNA ligase, mitochondrial chr6 GO:0005524 Not Cancer Driver No 111 0.104 253 21 0.083 3
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0005524 Not Cancer Driver No 88 0.109 186 16 0.086 16
VPS4A VPS4A Q9UN37 Vacuolar protein sorting-associated protein 4A chr16 GO:0005524 Not Cancer Driver No 48 0.11 167 17 0.102 4
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0005524 Not Cancer Driver No 52 0.117 195 22 0.113 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 GO:0005524 Not Cancer Driver No 52 0.131 80 9 0.113 0
VRK2 VRK2 Q86Y07 Serine/threonine-protein kinase VRK2 chr2 GO:0005524 Not Cancer Driver No 63 0.124 126 15 0.119 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0005524 Not Cancer Driver No 65 0.137 180 18 0.1 0
VWA8 VWA8 A3KMH1 von Willebrand factor A domain-containing protein 8 chr13 GO:0005524 Not Cancer Driver No 246 0.129 384 36 0.094 0
WARS WARS1 P23381 Tryptophan--tRNA ligase, cytoplasmic chr14 GO:0005524 Not Cancer Driver No 62 0.132 90 13 0.144 1
WARS2 WARS2 Q9UGM6 Tryptophan--tRNA ligase, mitochondrial chr1 GO:0005524 Not Cancer Driver No 67 0.186 31 4 0.129 5
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 GO:0005524 Not Cancer Driver No 60 0.093 399 27 0.068 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0005524 Not Cancer Driver No 104 0.183 345 65 0.188 1
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0005524 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:0005524 Census, Compendium Yes 223 0.097 1868 167 0.089 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0005524 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNK4 WNK4 Q96J92 Serine/threonine-protein kinase WNK4 chr17 GO:0005524 Compendium Yes 178 0.143 916 126 0.138 4
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0005524 Census, Compendium Yes 164 0.115 373 41 0.11 2
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 GO:0005524 Not Cancer Driver No 50 0.075 292 7 0.024 0
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0005524 Not Cancer Driver No 36 0.129 9 1 0.111 2
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0005524 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0005524 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0005524 Not Cancer Driver No 66 0.108 140 12 0.086 0
XYLB XYLB O75191 Xylulose kinase chr3 GO:0005524 Not Cancer Driver No 90 0.168 22 4 0.182 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 GO:0005524 Not Cancer Driver No 62 0.117 109 9 0.083 3
YARS2 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 GO:0005524 Not Cancer Driver No 59 0.124 62 11 0.177 2
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0005524 Not Cancer Driver No 65 0.12 62 10 0.161 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 GO:0005524 Not Cancer Driver No 112 0.145 136 14 0.103 1
YTHDC2 YTHDC2 Q9H6S0 3'-5' RNA helicase YTHDC2 chr5 GO:0005524 Not Cancer Driver No 163 0.114 439 48 0.109 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0005524 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZRANB3 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:0005524 Not Cancer Driver No 126 0.117 261 31 0.119 0