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Total number of protein in "GO:0046887" GO term:  112

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AACS AACS Q86V21 Acetoacetyl-CoA synthetase chr12 GO:0046887 Not Cancer Driver No 92 0.137 16 0 0.0 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0046887 Not Cancer Driver No 84 0.168 28 5 0.179 1
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0046887 Not Cancer Driver No 97 0.136 77 12 0.156 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0046887 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1_ENST00000450565 ADCYAP1 P18509 Pituitary adenylate cyclase-activating polypeptide chr18 GO:0046887 Not Cancer Driver No 43 0.244 75 11 0.147 0
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 GO:0046887 Not Cancer Driver No 31 0.099 161 19 0.118 0
ANO1 ANO1 Q5XXA6 Anoctamin-1 chr11 GO:0046887 Not Cancer Driver No 155 0.157 168 14 0.083 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0046887 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0046887 Not Cancer Driver No 170 0.143 230 35 0.152 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0046887 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0046887 Not Cancer Driver No 95 0.185 226 51 0.226 0
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0046887 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0046887 Not Cancer Driver No 61 0.217 96 17 0.177 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0046887 Not Cancer Driver No 42 0.171 73 14 0.192 0
C2CD2L C2CD2L O14523 Phospholipid transfer protein C2CD2L chr11 GO:0046887 Not Cancer Driver No 77 0.109 491 65 0.132 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0046887 Not Cancer Driver No 87 0.129 52 6 0.115 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0046887 Not Cancer Driver No 304 0.282 189 60 0.317 108
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0046887 Not Cancer Driver No 54 0.18 3 1 0.333 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0046887 Not Cancer Driver No 287 0.194 145 18 0.124 151
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0046887 Census Yes 25 0.076 277 23 0.083 0
CRH CRH P06850 Corticoliberin chr8 GO:0046887 Not Cancer Driver No 10 0.051 131 9 0.069 0
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0046887 Not Cancer Driver No 91 0.181 2 1 0.5 5
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0046887 Not Cancer Driver No 144 0.187 680 125 0.184 0
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0046887 Not Cancer Driver No 10 0.024 197 3 0.015 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0046887 Not Cancer Driver No 127 0.287 124 45 0.363 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0046887 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0046887 Not Cancer Driver No 69 0.29 140 44 0.314 3
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0046887 Not Cancer Driver No 45 0.15 2 0 0.0 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0046887 Not Cancer Driver No 47 0.13 0 0 0.0 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0046887 Census, Compendium Yes 39 0.104 257 20 0.078 26
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0046887 Not Cancer Driver No 150 0.156 142 17 0.12 0
GAL GAL P22466 Galanin peptides chr11 GO:0046887 Not Cancer Driver No 17 0.138 36 2 0.056 1
GALR1 GALR1 P47211 Galanin receptor type 1 chr18 GO:0046887 Not Cancer Driver No 68 0.195 32 2 0.062 0
GCG GCG P01275 Pro-glucagon chr2 GO:0046887 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0046887 Not Cancer Driver No 88 0.189 73 14 0.192 107
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0046887 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0046887 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0046887 Not Cancer Driver No 20 0.171 52 11 0.212 0
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0046887 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0046887 Not Cancer Driver No 45 0.097 41 0 0.0 0
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0046887 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0046887 Not Cancer Driver No 66 0.177 104 21 0.202 2
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0046887 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0046887 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR27 GPR27 Q9NS67 Probable G-protein coupled receptor 27 chr3 GO:0046887 Not Cancer Driver No 26 0.069 23 1 0.043 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0046887 Not Cancer Driver No 42 0.115 45 1 0.022 1
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0046887 Not Cancer Driver No 78 0.215 43 8 0.186 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0046887 Census Yes 118 0.143 435 51 0.117 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0046887 Not Cancer Driver No 48 0.18 12 1 0.083 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0046887 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0046887 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0046887 Not Cancer Driver No 61 0.15 98 5 0.051 0
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0046887 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0046887 Not Cancer Driver No 85 0.244 180 41 0.228 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0046887 Census, Compendium Yes 136 0.12 59 5 0.085 5
KISS1 KISS1 Q15726 Metastasis-suppressor KiSS-1 chr1 GO:0046887 Not Cancer Driver No 17 0.123 116 14 0.121 1
LEP LEP P41159 Leptin chr7 GO:0046887 Not Cancer Driver No 29 0.174 0 0 0.0 2
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0046887 Not Cancer Driver No 105 0.13 32 3 0.094 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0046887 Not Cancer Driver No 41 0.117 13 0 0.0 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0046887 Not Cancer Driver No 13 0.102 0 0 0.0 0
MYRIP MYRIP Q8NFW9 Rab effector MyRIP chr3 GO:0046887 Not Cancer Driver No 133 0.155 599 95 0.159 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0046887 Not Cancer Driver No 35 0.15 171 16 0.094 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0046887 Not Cancer Driver No 38 0.104 325 34 0.105 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0046887 Not Cancer Driver No 91 0.109 300 19 0.063 0
NMB_ENST00000360476 NMB P08949 Neuromedin-B chr15 GO:0046887 Not Cancer Driver No 6 0.05 30 2 0.067 0
NNAT NNAT Q16517 Neuronatin chr20 GO:0046887 Not Cancer Driver No 9 0.111 8 0 0.0 0
NR0B2 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0046887 Not Cancer Driver No 35 0.136 10 2 0.2 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0046887 Not Cancer Driver No 111 0.228 78 18 0.231 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0046887 Not Cancer Driver No 83 0.103 386 39 0.101 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0046887 Not Cancer Driver No 80 0.154 39 5 0.128 11
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0046887 Not Cancer Driver No 60 0.161 16 1 0.062 0
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0046887 Not Cancer Driver No 91 0.142 139 13 0.094 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0046887 Not Cancer Driver No 32 0.113 238 23 0.097 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0046887 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0046887 Not Cancer Driver No 80 0.103 70 8 0.114 9
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0046887 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0046887 Not Cancer Driver No 108 0.134 148 23 0.155 11
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0046887 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0046887 Census Yes 72 0.143 44 4 0.091 3
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0046887 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0046887 Not Cancer Driver No 107 0.145 170 26 0.153 0
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 GO:0046887 Not Cancer Driver No 22 0.099 173 16 0.092 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0046887 Census, Compendium Yes 129 0.218 260 38 0.146 60
RAB8B RAB8B Q92930 Ras-related protein Rab-8B chr15 GO:0046887 Not Cancer Driver No 22 0.106 29 2 0.069 0
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0046887 Not Cancer Driver No 30 0.149 8 1 0.125 4
RETN RETN Q9HD89 Resistin chr19 GO:0046887 Not Cancer Driver No 10 0.093 0 0 0.0 0
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 GO:0046887 Not Cancer Driver No 239 0.258 422 94 0.223 3
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0046887 Not Cancer Driver No 40 0.127 162 20 0.123 0
SCT SCT P09683 Secretin chr11 GO:0046887 Not Cancer Driver No 4 0.033 71 3 0.042 0
SELENOT SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:0046887 Not Cancer Driver No 25 0.128 0 0 0.0 0
SERP1_ENST00000239944 SERP1 Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 chr3 GO:0046887 Not Cancer Driver No 6 0.091 30 2 0.067 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0046887 Not Cancer Driver No 115 0.312 25 9 0.36 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0046887 Census, Compendium Yes 198 0.359 195 17 0.087 8
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0046887 Not Cancer Driver No 31 0.069 101 5 0.05 0
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0046887 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0046887 Not Cancer Driver No 28 0.059 400 24 0.06 4
SPP1 SPP1 P10451 Osteopontin chr4 GO:0046887 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRI SRI P30626 Sorcin chr7 GO:0046887 Not Cancer Driver No 15 0.076 32 2 0.062 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0046887 Not Cancer Driver No 50 0.168 152 20 0.132 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0046887 Not Cancer Driver No 69 0.17 28 2 0.071 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0046887 Census, Compendium Yes 122 0.197 516 93 0.18 0
TM7SF3 TM7SF3 Q9NS93 Transmembrane 7 superfamily member 3 chr12 GO:0046887 Not Cancer Driver No 83 0.146 18 4 0.222 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 GO:0046887 Not Cancer Driver No 109 0.1 946 99 0.105 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0046887 Not Cancer Driver No 52 0.164 56 1 0.018 1
TRH TRH P20396 Pro-thyrotropin-releasing hormone chr3 GO:0046887 Not Cancer Driver No 45 0.186 217 41 0.189 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0046887 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0046887 Not Cancer Driver No 152 0.125 149 18 0.121 12
UCN UCN P55089 Urocortin chr2 GO:0046887 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0046887 Not Cancer Driver No 22 0.137 74 11 0.149 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0046887 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0046887 Not Cancer Driver No 9 0.09 27 0 0.0 0
VSNL1_ENST00000404666 VSNL1 P62760 Visinin-like protein 1 chr2 GO:0046887 Not Cancer Driver No 28 0.147 15 3 0.2 0