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Total number of protein in "GO:0050806" GO term:  126

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0050806 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0050806 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0050806 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0050806 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0050806 Not Cancer Driver No 130 0.279 40 8 0.2 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0050806 Not Cancer Driver No 31 0.077 297 21 0.071 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0050806 Not Cancer Driver No 37 0.087 405 34 0.084 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0050806 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0050806 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0050806 Not Cancer Driver No 46 0.112 122 22 0.18 0
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0050806 Not Cancer Driver No 170 0.143 230 35 0.152 0
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 GO:0050806 Not Cancer Driver No 41 0.158 55 8 0.145 4
CA7 CA7 P43166 Carbonic anhydrase 7 chr16 GO:0050806 Not Cancer Driver No 22 0.083 65 5 0.077 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0050806 Not Cancer Driver No 155 0.235 478 106 0.222 0
CACNG2 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 GO:0050806 Not Cancer Driver No 57 0.176 90 16 0.178 1
CACNG3 CACNG3 O60359 Voltage-dependent calcium channel gamma-3 subunit chr16 GO:0050806 Not Cancer Driver No 126 0.4 69 37 0.536 0
CACNG4 CACNG4 Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit chr17 GO:0050806 Not Cancer Driver No 51 0.156 71 17 0.239 0
CACNG5_ENST00000307139 CACNG5 Q9UF02 Voltage-dependent calcium channel gamma-5 subunit chr17 GO:0050806 Not Cancer Driver No 77 0.28 1 0 0.0 0
CACNG7 CACNG7 P62955 Voltage-dependent calcium channel gamma-7 subunit chr19 GO:0050806 Not Cancer Driver No 99 0.36 9 1 0.111 0
CACNG8 CACNG8 Q8WXS5 Voltage-dependent calcium channel gamma-8 subunit chr19 GO:0050806 Not Cancer Driver No 47 0.111 205 15 0.073 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0050806 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0050806 Not Cancer Driver No 81 0.217 23 1 0.043 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0050806 Not Cancer Driver No 48 0.164 5 1 0.2 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0050806 Not Cancer Driver No 71 0.141 18 4 0.222 0
CLSTN1 CLSTN1 O94985 Calsyntenin-1 chr1 GO:0050806 Not Cancer Driver No 110 0.112 271 22 0.081 0
CLSTN2 CLSTN2 Q9H4D0 Calsyntenin-2 chr3 GO:0050806 Not Cancer Driver No 232 0.243 177 41 0.232 0
CLSTN3 CLSTN3 Q9BQT9 Calsyntenin-3 chr12 GO:0050806 Not Cancer Driver No 140 0.146 211 27 0.128 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0050806 Not Cancer Driver No 129 0.273 9 1 0.111 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:0050806 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0050806 Census, Compendium Yes 63 0.099 606 62 0.102 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0050806 Not Cancer Driver No 116 0.16 232 55 0.237 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0050806 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0050806 Not Cancer Driver No 127 0.287 124 45 0.363 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0050806 Not Cancer Driver No 49 0.14 210 25 0.119 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0050806 Not Cancer Driver No 156 0.095 494 44 0.089 2
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0050806 Not Cancer Driver No 186 0.176 119 17 0.143 7
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0050806 Not Cancer Driver No 43 0.101 122 15 0.123 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0050806 Not Cancer Driver No 124 0.196 327 70 0.214 3
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0050806 Not Cancer Driver No 65 0.15 288 42 0.146 62
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0050806 Not Cancer Driver No 35 0.229 68 16 0.235 0
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0050806 Not Cancer Driver No 66 0.177 104 21 0.202 2
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0050806 Not Cancer Driver No 65 0.173 13 5 0.385 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0050806 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0050806 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0050806 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 GO:0050806 Not Cancer Driver No 111 0.09 276 6 0.022 0
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 GO:0050806 Not Cancer Driver No 125 0.094 467 15 0.032 1
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0050806 Not Cancer Driver No 97 0.145 454 60 0.132 0
IGSF11 IGSF11 Q5DX21 Immunoglobulin superfamily member 11 chr3 GO:0050806 Not Cancer Driver No 98 0.227 159 28 0.176 0
INS INS P01308 Insulin chr11 GO:0050806 Not Cancer Driver No 15 0.136 5 1 0.2 22
ITPR3 ITPR3 Q14573 Inositol 1,4,5-trisphosphate receptor type 3 chr6 GO:0050806 Not Cancer Driver No 336 0.126 385 44 0.114 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0050806 Not Cancer Driver No 33 0.1 95 10 0.105 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0050806 Census, Compendium Yes 122 0.127 586 67 0.114 0
KISS1 KISS1 Q15726 Metastasis-suppressor KiSS-1 chr1 GO:0050806 Not Cancer Driver No 17 0.123 116 14 0.121 1
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0050806 Not Cancer Driver No 77 0.158 0 0 0.0 0
LAMA2 LAMA2 P24043 Laminin subunit alpha-2 chr6 GO:0050806 Not Cancer Driver No 629 0.201 658 127 0.193 11
LGI1 LGI1 O95970 Leucine-rich glioma-inactivated protein 1 chr10 GO:0050806 Not Cancer Driver No 87 0.156 3 1 0.333 17
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0050806 Not Cancer Driver No 57 0.132 112 19 0.17 0
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 GO:0050806 Not Cancer Driver No 172 0.33 57 17 0.298 0
LRRTM2 LRRTM2 O43300 Leucine-rich repeat transmembrane neuronal protein 2 chr5 GO:0050806 Not Cancer Driver No 57 0.11 33 1 0.03 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0050806 Census, Compendium Yes 62 0.172 2 0 0.0 7
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0050806 Not Cancer Driver No 75 0.154 483 74 0.153 46
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0050806 Not Cancer Driver No 189 0.252 40 17 0.425 4
MPP2_ENST00000461854 MPP2 Q14168 MAGUK p55 subfamily member 2 chr17 GO:0050806 Not Cancer Driver No 109 0.189 112 18 0.161 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0050806 Not Cancer Driver No 155 0.172 685 120 0.175 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0050806 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0050806 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0050806 Not Cancer Driver No 158 0.186 257 54 0.21 2
NMU NMU P48645 Neuromedin-U chr4 GO:0050806 Not Cancer Driver No 22 0.126 31 2 0.065 0
NPS NPS P0C0P6 Neuropeptide S chr10 GO:0050806 Not Cancer Driver No 27 0.303 5 2 0.4 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0050806 Not Cancer Driver No 47 0.118 118 9 0.076 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0050806 Not Cancer Driver No 75 0.195 57 6 0.105 0
NRGN NRGN Q92686 Neurogranin chr11 GO:0050806 Not Cancer Driver No 5 0.064 76 5 0.066 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0050806 Not Cancer Driver No 593 0.401 301 110 0.365 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0050806 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0050806 Not Cancer Driver No 155 0.189 117 18 0.154 1
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0050806 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0050806 Not Cancer Driver No 46 0.118 18 0 0.0 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0050806 Not Cancer Driver No 57 0.098 99 13 0.131 23
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0050806 Not Cancer Driver No 92 0.134 178 21 0.118 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0050806 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0050806 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0050806 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRRT1 PRRT1 Q99946 Proline-rich transmembrane protein 1 chr6 GO:0050806 Not Cancer Driver No 36 0.118 190 19 0.1 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0050806 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0050806 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0050806 Not Cancer Driver No 161 0.16 261 37 0.142 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0050806 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAPSN RAPSN Q13702 43 kDa receptor-associated protein of the synapse chr11 GO:0050806 Not Cancer Driver No 38 0.092 10 0 0.0 8
RASGRF2 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 GO:0050806 Not Cancer Driver No 216 0.175 274 55 0.201 0
RELN RELN P78509 Reelin chr7 GO:0050806 Not Cancer Driver No 761 0.22 107 19 0.178 7
RETN RETN Q9HD89 Resistin chr19 GO:0050806 Not Cancer Driver No 10 0.093 0 0 0.0 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0050806 Not Cancer Driver No 57 0.101 309 37 0.12 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0050806 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIMS3 RIMS3 Q9UJD0 Regulating synaptic membrane exocytosis protein 3 chr1 GO:0050806 Not Cancer Driver No 61 0.198 162 39 0.241 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0050806 Not Cancer Driver No 203 0.215 299 71 0.237 5
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0050806 Not Cancer Driver No 62 0.156 0 0 0.0 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0050806 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SHISA7 SHISA7 A6NL88 Protein shisa-7 chr19 GO:0050806 Not Cancer Driver No 13 0.024 429 12 0.028 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0050806 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0050806 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC24A1 SLC24A1 O60721 Sodium/potassium/calcium exchanger 1 chr15 GO:0050806 Not Cancer Driver No 105 0.096 595 53 0.089 0
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0050806 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0050806 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0050806 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0050806 Not Cancer Driver No 263 0.284 152 35 0.23 0
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0050806 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0050806 Not Cancer Driver No 21 0.15 107 13 0.121 5
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0050806 Not Cancer Driver No 54 0.123 267 32 0.12 30
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 GO:0050806 Not Cancer Driver No 77 0.133 456 63 0.138 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0050806 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0050806 Not Cancer Driver No 38 0.132 155 20 0.129 2
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0050806 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0050806 Not Cancer Driver No 50 0.168 152 20 0.132 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0050806 Not Cancer Driver No 97 0.163 111 23 0.207 18
SYT12_ENST00000527043 SYT12 Q8IV01 Synaptotagmin-12 chr11 GO:0050806 Not Cancer Driver No 71 0.169 73 13 0.178 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0050806 Not Cancer Driver No 104 0.246 103 36 0.35 5
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0050806 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACR2 TACR2 P21452 Substance-K receptor chr10 GO:0050806 Not Cancer Driver No 61 0.153 11 4 0.364 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0050806 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNR TNR Q92752 Tenascin-R chr1 GO:0050806 Not Cancer Driver No 496 0.365 358 128 0.358 0
TSHZ3 TSHZ3 Q63HK5 Teashirt homolog 3 chr19 GO:0050806 Not Cancer Driver No 354 0.327 869 281 0.323 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0050806 Not Cancer Driver No 7 0.06 47 4 0.085 3
ZDHHC12 ZDHHC12 Q96GR4 Palmitoyltransferase ZDHHC12 chr9 GO:0050806 Not Cancer Driver No 23 0.086 13 1 0.077 0
ZDHHC2 ZDHHC2 Q9UIJ5 Palmitoyltransferase ZDHHC2 chr8 GO:0050806 Not Cancer Driver No 47 0.128 73 6 0.082 0
ZDHHC3_ENST00000424952 ZDHHC3 Q9NYG2 Palmitoyltransferase ZDHHC3 chr3 GO:0050806 Not Cancer Driver No 31 0.104 0 0 0.0 0