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HLX ,HLX ,Q14774
  • Number of GO Term: 69
GO term GO name GO namespace GO def
GO:0048856 anatomical structure development biological_process The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [GO_REF:0000021]
GO:0050865 regulation of cell activation biological_process Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. [GOC:ai]
GO:0002683 negative regulation of immune system process biological_process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. [GOC:add]
GO:0022407 regulation of cell-cell adhesion biological_process Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. [GOC:isa_complete]
GO:0045597 positive regulation of cell differentiation biological_process Any process that activates or increases the frequency, rate or extent of cell differentiation. [GOC:go_curators]
GO:0030154 cell differentiation biological_process The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [ISBN:0198506732]
GO:0002819 regulation of adaptive immune response biological_process Any process that modulates the frequency, rate, or extent of an adaptive immune response. [GOC:add]
GO:0002696 positive regulation of leukocyte activation biological_process Any process that activates or increases the frequency, rate, or extent of leukocyte activation. [GOC:add]
GO:0050863 regulation of T cell activation biological_process Any process that modulates the frequency, rate or extent of T cell activation. [GOC:ai]
GO:0051239 regulation of multicellular organismal process biological_process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai, GOC:dph, GOC:tb]
GO:0009887 animal organ morphogenesis biological_process Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544]
GO:0051094 positive regulation of developmental process biological_process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:ai]
GO:1903038 negative regulation of leukocyte cell-cell adhesion biological_process Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532]
GO:0002684 positive regulation of immune system process biological_process Any process that activates or increases the frequency, rate, or extent of an immune system process. [GOC:add]
GO:0001889 liver development biological_process The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. [GOC:add, ISBN:068340007X]
GO:0050789 regulation of biological process biological_process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators]
GO:0048518 positive regulation of biological process biological_process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid]
GO:0007162 negative regulation of cell adhesion biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. [GOC:go_curators]
GO:0009653 anatomical structure morphogenesis biological_process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. [GOC:go_curators, ISBN:0521436125]
GO:0051251 positive regulation of lymphocyte activation biological_process Any process that activates or increases the frequency, rate or extent of lymphocyte activation. [GOC:ai]
GO:0050866 negative regulation of cell activation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. [GOC:ai]
GO:0051240 positive regulation of multicellular organismal process biological_process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai]
GO:2000026 regulation of multicellular organismal development biological_process Any process that modulates the frequency, rate or extent of multicellular organismal development. [GOC:obol]
GO:0048522 positive regulation of cellular process biological_process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid]
GO:0050868 negative regulation of T cell activation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. [GOC:ai]
GO:0050867 positive regulation of cell activation biological_process Any process that activates or increases the frequency, rate or extent of activation. [GOC:ai]
GO:0002682 regulation of immune system process biological_process Any process that modulates the frequency, rate, or extent of an immune system process. [GOC:add]
GO:0007519 skeletal muscle tissue development biological_process The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are
GO:0048523 negative regulation of cellular process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid]
GO:0043565 sequence-specific DNA binding molecular_function Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. [GOC:jl]
GO:0002697 regulation of immune effector process biological_process Any process that modulates the frequency, rate, or extent of an immune effector process. [GOC:add]
GO:0002694 regulation of leukocyte activation biological_process Any process that modulates the frequency, rate, or extent of leukocyte activation. [GOC:add]
GO:0065007 biological regulation biological_process Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
GO:1903706 regulation of hemopoiesis biological_process Any process that modulates the frequency, rate or extent of hemopoiesis. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761]
GO:0050778 positive regulation of immune response biological_process Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai]
GO:0032502 developmental process biological_process A biological process whose specific outcome is the progression of an integrated living unit
GO:0051250 negative regulation of lymphocyte activation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. [GOC:ai]
GO:0050793 regulation of developmental process biological_process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:go_curators]
GO:0007275 multicellular organism development biological_process The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb]
GO:0048585 negative regulation of response to stimulus biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid]
GO:0022408 negative regulation of cell-cell adhesion biological_process Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. [GOC:isa_complete]
GO:0045927 positive regulation of growth biological_process Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. [GOC:go_curators]
GO:0048584 positive regulation of response to stimulus biological_process Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid]
GO:0048562 embryonic organ morphogenesis biological_process Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:jid]
GO:0022409 positive regulation of cell-cell adhesion biological_process Any process that activates or increases the rate or extent of cell adhesion to another cell. [GOC:isa_complete]
GO:0051241 negative regulation of multicellular organismal process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. [GOC:ai]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0002695 negative regulation of leukocyte activation biological_process Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. [GOC:add]
GO:0002699 positive regulation of immune effector process biological_process Any process that activates or increases the frequency, rate, or extent of an immune effector process. [GOC:add]
GO:0045595 regulation of cell differentiation biological_process Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. [GOC:go_curators]
GO:0000785 chromatin cellular_component The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. [GOC:elh, PMID:20404130]
GO:1903037 regulation of leukocyte cell-cell adhesion biological_process Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532]
GO:0050870 positive regulation of T cell activation biological_process Any process that activates or increases the frequency, rate or extent of T cell activation. [GOC:ai]
GO:0006357 regulation of transcription by RNA polymerase II biological_process Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0051249 regulation of lymphocyte activation biological_process Any process that modulates the frequency, rate or extent of lymphocyte activation. [GOC:ai]
GO:0030155 regulation of cell adhesion biological_process Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. [GOC:mah]
GO:0050794 regulation of cellular process biological_process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators]
GO:0008284 positive regulation of cell population proliferation biological_process Any process that activates or increases the rate or extent of cell proliferation. [GOC:go_curators]
GO:0045785 positive regulation of cell adhesion biological_process Any process that activates or increases the frequency, rate or extent of cell adhesion. [GOC:go_curators]
GO:0048583 regulation of response to stimulus biological_process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid]
GO:0048731 system development biological_process The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. [GOC:dph, GOC:jid]
GO:0045582 positive regulation of T cell differentiation biological_process Any process that activates or increases the frequency, rate or extent of T cell differentiation. [GOC:go_curators]
GO:1903039 positive regulation of leukocyte cell-cell adhesion biological_process Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532]
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. [GOC:txnOH-2018]
GO:0048519 negative regulation of biological process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid]
GO:0048598 embryonic morphogenesis biological_process The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. [GOC:jid, GOC:mtg_sensu]
GO:0040008 regulation of growth biological_process Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. [GOC:ems, GOC:mah]
GO:0050776 regulation of immune response biological_process Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]