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Total number of protein in "GO:0048562" GO term:  118

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AC012531.3 AC012531.3 V9GYH0 Homeobox domain-containing protein (Fragment) chr12 GO:0048562 Not Cancer Driver No 23 0.183 102 17 0.167 0
ALDH1A3 ALDH1A3 P47895 Aldehyde dehydrogenase family 1 member A3 chr15 GO:0048562 Not Cancer Driver No 74 0.145 73 7 0.096 10
ALX1 ALX1 Q15699 ALX homeobox protein 1 chr12 GO:0048562 Not Cancer Driver No 75 0.23 190 48 0.253 0
ALX3 ALX3 O95076 Homeobox protein aristaless-like 3 chr1 GO:0048562 Not Cancer Driver No 37 0.108 303 33 0.109 4
ALX4 ALX4 Q9H161 Homeobox protein aristaless-like 4 chr11 GO:0048562 Not Cancer Driver No 98 0.238 320 77 0.241 4
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0048562 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0048562 Not Cancer Driver No 91 0.211 69 18 0.261 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0048562 Not Cancer Driver No 23 0.085 230 18 0.078 0
COL11A1 COL11A1 P12107 Collagen alpha-1(XI) chain chr1 GO:0048562 Not Cancer Driver No 749 0.415 1436 617 0.43 8
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0048562 Census Yes 258 0.174 1215 207 0.17 64
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0048562 Census, Compendium Yes 415 0.531 288 301 1.045 14
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0048562 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0048562 Not Cancer Driver No 46 0.14 262 38 0.145 0
DSCAML1 DSCAML1 Q8TD84 Down syndrome cell adhesion molecule-like protein 1 chr11 GO:0048562 Not Cancer Driver No 419 0.204 739 136 0.184 0
EFEMP1_ENST00000355426 EFEMP1 Q12805 EGF-containing fibulin-like extracellular matrix protein 1 chr2 GO:0048562 Not Cancer Driver No 95 0.193 73 21 0.288 1
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0048562 Not Cancer Driver No 50 0.122 57 6 0.105 1
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0048562 Not Cancer Driver No 168 0.284 341 99 0.29 15
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0048562 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0048562 Compendium Yes 607 0.208 135 24 0.178 30
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0048562 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0048562 Census, Compendium Yes 238 0.29 228 44 0.193 72
FLVCR1 FLVCR1 Q9Y5Y0 Feline leukemia virus subgroup C receptor-related protein 1 chr1 GO:0048562 Not Cancer Driver No 58 0.105 117 14 0.12 4
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 GO:0048562 Not Cancer Driver No 38 0.102 133 5 0.038 4
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0048562 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXF2 FOXF2 Q12947 Forkhead box protein F2 chr6 GO:0048562 Not Cancer Driver No 44 0.099 277 10 0.036 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0048562 Census, Compendium Yes 39 0.104 257 20 0.078 26
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0048562 Not Cancer Driver No 38 0.091 43 4 0.093 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0048562 Not Cancer Driver No 45 0.077 58 4 0.069 0
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0048562 Not Cancer Driver No 42 0.161 12 4 0.333 4
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0048562 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0048562 Not Cancer Driver No 95 0.152 258 43 0.167 2
GSC GSC P56915 Homeobox protein goosecoid chr14 GO:0048562 Not Cancer Driver No 17 0.066 109 11 0.101 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0048562 Not Cancer Driver No 158 0.131 565 89 0.158 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0048562 Not Cancer Driver No 154 0.129 686 96 0.14 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0048562 Not Cancer Driver No 107 0.219 412 98 0.238 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0048562 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA3_ENST00000396352 HOXA3 O43365 Homeobox protein Hox-A3 chr7 GO:0048562 Not Cancer Driver No 86 0.194 417 84 0.201 0
HOXA4_ENST00000610970 HOXA4 Q00056 Homeobox protein Hox-A4 chr7 GO:0048562 Not Cancer Driver No 38 0.119 255 25 0.098 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 GO:0048562 Not Cancer Driver No 43 0.159 209 37 0.177 0
HOXA6 HOXA6 P31267 Homeobox protein Hox-A6 chr7 GO:0048562 Not Cancer Driver No 50 0.215 90 20 0.222 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0048562 Not Cancer Driver No 60 0.261 71 15 0.211 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 GO:0048562 Census Yes 46 0.169 187 35 0.187 0
HOXB1 HOXB1 P14653 Homeobox protein Hox-B1 chr17 GO:0048562 Not Cancer Driver No 71 0.236 276 68 0.246 1
HOXB2 HOXB2 P14652 Homeobox protein Hox-B2 chr17 GO:0048562 Not Cancer Driver No 47 0.132 269 35 0.13 0
HOXB3_ENST00000498678 HOXB3 P14651 Homeobox protein Hox-B3 chr17 GO:0048562 Not Cancer Driver No 74 0.172 398 66 0.166 0
HOXB4 HOXB4 P17483 Homeobox protein Hox-B4 chr17 GO:0048562 Not Cancer Driver No 41 0.163 210 33 0.157 0
HOXB5 HOXB5 P09067 Homeobox protein Hox-B5 chr17 GO:0048562 Not Cancer Driver No 40 0.149 203 26 0.128 0
HOXB6_ENST00000225648 HOXB6 P17509 Homeobox protein Hox-B6 chr17 GO:0048562 Not Cancer Driver No 31 0.138 103 20 0.194 0
HOXB7 HOXB7 P09629 Homeobox protein Hox-B7 chr17 GO:0048562 Not Cancer Driver No 25 0.115 84 10 0.119 0
HOXB8 HOXB8 P17481 Homeobox protein Hox-B8 chr17 GO:0048562 Not Cancer Driver No 35 0.144 121 15 0.124 0
HOXB9 HOXB9 P17482 Homeobox protein Hox-B9 chr17 GO:0048562 Not Cancer Driver No 28 0.112 191 27 0.141 0
HOXC11 HOXC11 O43248 Homeobox protein Hox-C11 chr12 GO:0048562 Census Yes 35 0.115 157 16 0.102 0
HOXC4 HOXC4 P09017 Homeobox protein Hox-C4 chr12 GO:0048562 Not Cancer Driver No 40 0.152 227 33 0.145 0
HOXC9 HOXC9 P31274 Homeobox protein Hox-C9 chr12 GO:0048562 Not Cancer Driver No 30 0.115 143 14 0.098 0
HOXD10 HOXD10 P28358 Homeobox protein Hox-D10 chr2 GO:0048562 Not Cancer Driver No 74 0.218 230 55 0.239 1
HOXD3 HOXD3 P31249 Homeobox protein Hox-D3 chr2 GO:0048562 Not Cancer Driver No 68 0.157 354 64 0.181 0
HOXD4 HOXD4 P09016 Homeobox protein Hox-D4 chr2 GO:0048562 Not Cancer Driver No 62 0.243 211 41 0.194 0
HOXD9 HOXD9 P28356 Homeobox protein Hox-D9 chr2 GO:0048562 Not Cancer Driver No 47 0.134 276 30 0.109 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0048562 Not Cancer Driver No 47 0.108 9 0 0.0 1
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0048562 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFT140 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 GO:0048562 Not Cancer Driver No 176 0.12 161 27 0.168 10
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0048562 Not Cancer Driver No 219 0.125 96 10 0.104 8
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0048562 Not Cancer Driver No 58 0.141 111 15 0.135 6
IRX5 IRX5 P78411 Iroquois-class homeodomain protein IRX-5 chr16 GO:0048562 Not Cancer Driver No 85 0.176 359 62 0.173 2
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0048562 Not Cancer Driver No 187 0.14 617 90 0.146 0
MDFI MDFI Q99750 MyoD family inhibitor chr6 GO:0048562 Not Cancer Driver No 25 0.102 152 15 0.099 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0048562 Not Cancer Driver No 363 0.128 476 59 0.124 3
MFAP2 MFAP2 P55001 Microfibrillar-associated protein 2 chr1 GO:0048562 Not Cancer Driver No 19 0.104 72 11 0.153 0
MFAP5 MFAP5 Q13361 Microfibrillar-associated protein 5 chr12 GO:0048562 Not Cancer Driver No 51 0.295 30 10 0.333 1
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0048562 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP16 MMP16 P51512 Matrix metalloproteinase-16 chr8 GO:0048562 Not Cancer Driver No 235 0.387 168 61 0.363 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0048562 Not Cancer Driver No 103 0.404 122 60 0.492 1
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0048562 Not Cancer Driver No 84 0.236 202 52 0.257 2
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0048562 Compendium Yes 353 0.126 1528 184 0.12 37
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0048562 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0048562 Not Cancer Driver No 22 0.095 86 9 0.105 20
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0048562 Not Cancer Driver No 57 0.214 67 17 0.254 0
OSR2_ENST00000522510 OSR2 Q8N2R0 Protein odd-skipped-related 2 chr8 GO:0048562 Not Cancer Driver No 59 0.189 66 13 0.197 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0048562 Not Cancer Driver No 29 0.105 139 8 0.058 0
PAX5 PAX5 Q02548 Paired box protein Pax-5 chr9 GO:0048562 Census Yes 83 0.212 291 62 0.213 1
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0048562 Not Cancer Driver No 72 0.171 337 56 0.166 38
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0048562 Census, Compendium Yes 290 0.266 173 45 0.26 2
PPP1R35 PPP1R35 Q8TAP8 Protein phosphatase 1 regulatory subunit 35 chr7 GO:0048562 Not Cancer Driver No 19 0.075 207 15 0.072 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0048562 Census, Compendium Yes 69 0.282 205 49 0.239 1
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0048562 Not Cancer Driver No 82 0.181 164 24 0.146 0
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0048562 Not Cancer Driver No 30 0.149 8 1 0.125 4
RBPMS2 RBPMS2 Q6ZRY4 RNA-binding protein with multiple splicing 2 chr15 GO:0048562 Not Cancer Driver No 24 0.115 55 4 0.073 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0048562 Not Cancer Driver No 203 0.215 299 71 0.237 5
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0048562 Not Cancer Driver No 83 0.159 447 73 0.163 47
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 GO:0048562 Not Cancer Driver No 164 0.224 412 100 0.243 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0048562 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0048562 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0048562 Not Cancer Driver No 67 0.202 200 40 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0048562 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX2 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0048562 Census Yes 53 0.182 151 21 0.139 0
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0048562 Not Cancer Driver No 99 0.127 460 58 0.126 0
SLC39A1_ENST00000310483 SLC39A1 Q9NY26 Zinc transporter ZIP1 chr1 GO:0048562 Not Cancer Driver No 38 0.117 22 0 0.0 0
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 GO:0048562 Not Cancer Driver No 41 0.131 0 0 0.0 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0048562 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0048562 Census, Compendium Yes 97 0.228 111 19 0.171 5
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0048562 Not Cancer Driver No 61 0.138 368 53 0.144 2
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0048562 Not Cancer Driver No 66 0.085 587 37 0.063 0
TBX15 TBX15 Q96SF7 T-box transcription factor TBX15 chr1 GO:0048562 Not Cancer Driver No 141 0.234 388 88 0.227 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0048562 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0048562 Not Cancer Driver No 74 0.104 401 36 0.09 1
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0048562 Not Cancer Driver No 55 0.307 120 40 0.333 0
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0048562 Not Cancer Driver No 77 0.176 275 44 0.16 4
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0048562 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0048562 Census, Compendium Yes 106 0.187 60 16 0.267 25
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0048562 Not Cancer Driver No 61 0.116 149 21 0.141 38
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0048562 Not Cancer Driver No 23 0.114 132 11 0.083 7
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0048562 Not Cancer Driver No 34 0.117 210 22 0.105 0
WDR19 WDR19 Q8NEZ3 WD repeat-containing protein 19 chr4 GO:0048562 Not Cancer Driver No 117 0.087 19 0 0.0 11
WDR60 DYNC2I1 Q8WVS4 Cytoplasmic dynein 2 intermediate chain 1 chr7 GO:0048562 Not Cancer Driver No 131 0.123 520 63 0.121 1
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0048562 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0048562 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0048562 Not Cancer Driver No 47 0.132 11 4 0.364 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0048562 Census, Compendium Yes 246 0.219 831 200 0.241 8