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Total number of protein in "GO:0051250" GO term:  116

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0051250 Not Cancer Driver No 61 0.148 93 11 0.118 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0051250 Not Cancer Driver No 59 0.171 61 12 0.197 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0051250 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0051250 Not Cancer Driver No 25 0.071 58 3 0.052 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0051250 Census, Compendium Yes 469 0.153 225 39 0.173 41
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0051250 Not Cancer Driver No 168 0.188 341 64 0.188 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0051250 Not Cancer Driver No 150 0.191 394 73 0.185 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0051250 Census, Compendium Yes 134 0.19 328 67 0.204 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0051250 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0051250 Not Cancer Driver No 86 0.211 142 26 0.183 5
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0051250 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0051250 Not Cancer Driver No 92 0.176 24 2 0.083 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0051250 Census Yes 32 0.116 62 5 0.081 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0051250 Census, Compendium Yes 39 0.214 94 17 0.181 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0051250 Census Yes 160 0.163 562 104 0.185 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0051250 Census Yes 29 0.1 54 9 0.167 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0051250 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0051250 Census Yes 31 0.105 185 20 0.108 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0051250 Not Cancer Driver No 64 0.122 241 25 0.104 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0051250 Not Cancer Driver No 85 0.199 320 73 0.228 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0051250 Compendium Yes 383 0.188 151 42 0.278 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0051250 Not Cancer Driver No 64 0.163 135 14 0.104 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0051250 Not Cancer Driver No 37 0.166 3 0 0.0 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0051250 Census, Compendium Yes 275 0.219 314 41 0.131 1
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0051250 Not Cancer Driver No 75 0.144 243 38 0.156 1
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0051250 Census Yes 51 0.165 99 30 0.303 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0051250 Not Cancer Driver No 71 0.162 70 12 0.171 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0051250 Not Cancer Driver No 85 0.161 52 8 0.154 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0051250 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0051250 Not Cancer Driver No 38 0.088 186 16 0.086 10
GAL GAL P22466 Galanin peptides chr11 GO:0051250 Not Cancer Driver No 17 0.138 36 2 0.056 1
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0051250 Not Cancer Driver No 385 0.244 1352 327 0.242 7
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0051250 Not Cancer Driver No 69 0.229 17 2 0.118 3
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0051250 Not Cancer Driver No 55 0.158 27 2 0.074 11
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0051250 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0051250 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0051250 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB3 HMGB3 O15347 High mobility group protein B3 chrX GO:0051250 Not Cancer Driver No 37 0.185 182 32 0.176 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0051250 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0051250 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0051250 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0051250 Not Cancer Driver No 24 0.12 49 8 0.163 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0051250 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0051250 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0051250 Census Yes 24 0.157 6 1 0.167 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0051250 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0051250 Not Cancer Driver No 133 0.161 420 64 0.152 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0051250 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0051250 Not Cancer Driver No 148 0.347 154 63 0.409 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0051250 Not Cancer Driver No 176 0.148 578 90 0.156 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0051250 Compendium Yes 49 0.151 228 31 0.136 2
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0051250 Not Cancer Driver No 95 0.105 335 42 0.125 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0051250 Census, Compendium Yes 167 0.149 63 10 0.159 7
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0051250 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0051250 Not Cancer Driver No 46 0.176 16 6 0.375 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0051250 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:0051250 Not Cancer Driver No 14 0.103 54 5 0.093 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0051250 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGALS9B_ENST00000423676 LGALS9B Q3B8N2 Galectin-9B chr17 GO:0051250 Not Cancer Driver No 43 0.121 86 19 0.221 0
LGALS9C LGALS9C Q6DKI2 Galectin-9C chr17 GO:0051250 Not Cancer Driver No 32 0.09 80 6 0.075 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0051250 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0051250 Not Cancer Driver No 162 0.362 277 115 0.415 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0051250 Not Cancer Driver No 91 0.121 86 17 0.198 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0051250 Not Cancer Driver No 130 0.196 28 4 0.143 0
LST1_ENST00000438075 LST1 O00453 Leukocyte-specific transcript 1 protein chr6 GO:0051250 Not Cancer Driver No 3 0.031 36 2 0.056 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0051250 Census Yes 95 0.186 84 12 0.143 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0051250 Not Cancer Driver No 15 0.105 20 2 0.1 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0051250 Not Cancer Driver No 175 0.175 159 31 0.195 3
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0051250 Not Cancer Driver No 180 0.442 172 76 0.442 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0051250 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0051250 Not Cancer Driver No 22 0.1 44 4 0.091 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0051250 Not Cancer Driver No 9 0.079 11 1 0.091 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0051250 Not Cancer Driver No 70 0.131 269 38 0.141 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0051250 Not Cancer Driver No 35 0.103 327 33 0.101 0
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0051250 Census, Compendium Yes 33 0.121 41 13 0.317 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0051250 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0051250 Not Cancer Driver No 111 0.193 160 28 0.175 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0051250 Not Cancer Driver No 83 0.11 419 45 0.107 2
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0051250 Not Cancer Driver No 120 0.127 459 54 0.118 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0051250 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0051250 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRNP PRNP P04156 Major prion protein chr20 GO:0051250 Not Cancer Driver No 36 0.142 115 7 0.061 18
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0051250 Not Cancer Driver No 57 0.137 120 14 0.117 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0051250 Not Cancer Driver No 118 0.224 85 23 0.271 6
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0051250 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0051250 Not Cancer Driver No 128 0.107 703 81 0.115 0
RHBDD3 RHBDD3 Q9Y3P4 Rhomboid domain-containing protein 3 chr22 GO:0051250 Not Cancer Driver No 24 0.062 147 16 0.109 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0051250 Not Cancer Driver No 131 0.123 421 76 0.181 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0051250 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0051250 Not Cancer Driver No 59 0.142 331 45 0.136 0
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0051250 Not Cancer Driver No 112 0.3 291 85 0.292 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0051250 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0051250 Not Cancer Driver No 40 0.127 39 7 0.179 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0051250 Not Cancer Driver No 56 0.121 139 14 0.101 81
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0051250 Not Cancer Driver No 40 0.094 139 0 0.0 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0051250 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0051250 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0051250 Not Cancer Driver No 61 0.138 368 53 0.144 2
TARM1_ENST00000432826 TARM1 B6A8C7 T-cell-interacting, activating receptor on myeloid cells protein 1 chr19 GO:0051250 Not Cancer Driver No 13 0.048 21 1 0.048 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0051250 Not Cancer Driver No 58 0.13 192 32 0.167 0
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0051250 Not Cancer Driver No 70 0.131 348 50 0.144 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0051250 Not Cancer Driver No 55 0.084 280 26 0.093 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:0051250 Not Cancer Driver No 188 0.117 448 47 0.105 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0051250 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF13B TNFRSF13B O14836 Tumor necrosis factor receptor superfamily member 13B chr17 GO:0051250 Not Cancer Driver No 60 0.205 108 25 0.231 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0051250 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF21 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0051250 Not Cancer Driver No 98 0.15 280 46 0.164 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0051250 Not Cancer Driver No 28 0.153 1 0 0.0 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0051250 Not Cancer Driver No 27 0.121 19 3 0.158 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0051250 Not Cancer Driver No 119 0.134 197 17 0.086 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0051250 Not Cancer Driver No 24 0.212 28 8 0.286 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0051250 Not Cancer Driver No 52 0.167 135 19 0.141 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0051250 Not Cancer Driver No 28 0.246 35 11 0.314 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0051250 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0051250 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0051250 Not Cancer Driver No 22 0.076 187 17 0.091 0