Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AARSD1 | AARSD1 | Q9BTE6 | Alanyl-tRNA editing protein Aarsd1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 157 | 20 | 20 | 0 |
| ACLY_ENST00000590151 | ACLY | P53396 | ATP-citrate synthase | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 120 | 114 | 12 | 12 | 0 |
| ACP1_ENST00000272065 | ACP1 | P24666 | Low molecular weight phosphotyrosine protein phosphatase | chr2 | Not Cancer Driver | No | 1 | hippie | 28 | 13 | 2 | 2 | 0 |
| ACTBL2 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 73 | 29 | 5 | 5 | 0 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 92 | 21 | 21 | 1 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 52 | 35 | 4 | 4 | 0 |
| AJUBA | AJUBA | Q96IF1 | LIM domain-containing protein ajuba | chr14 | Compendium | Yes | 1 | hippie | 45 | 307 | 13 | 13 | 0 |
| AKR1B1 | AKR1B1 | P15121 | Aldo-keto reductase family 1 member B1 | chr7 | Not Cancer Driver | No | 1 | hippie | 52 | 19 | 1 | 1 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | Census | Yes | 1 | hippie | 77 | 84 | 9 | 9 | 2 |
| ALAS1_ENST00000484952 | ALAS1 | P13196 | 5-aminolevulinate synthase, non-specific, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 68 | 177 | 16 | 16 | 0 |
| ANKRD40 | ANKRD40 | Q6AI12 | Ankyrin repeat domain-containing protein 40 | chr17 | Not Cancer Driver | No | 1 | hippie | 43 | 204 | 28 | 28 | 0 |
| ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 49 | 20 | 4 | 4 | 0 |
| APOBEC3A_ENST00000249116 | APOBEC3A | P31941 | DNA dC->dU-editing enzyme APOBEC-3A | chr22 | Not Cancer Driver | No | 1 | hippie | 27 | 8 | 1 | 1 | 0 |
| APOBEC3B | APOBEC3B | Q9UH17 | DNA dC->dU-editing enzyme APOBEC-3B | chr22 | Census | Yes | 1 | hippie | 61 | 1 | 0 | 0 | 0 |
| APOBEC3F | APOBEC3F | Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | chr22 | Not Cancer Driver | No | 1 | hippie | 49 | 0 | 0 | 0 | 0 |
| APOBEC3H_ENST00000613677 | APOBEC3H | Q6NTF7 | DNA dC->dU-editing enzyme APOBEC-3H | chr22 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
| APRT | APRT | P07741 | Adenine phosphoribosyltransferase | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 16 | 0 | 0 | 0 | 8 |
| AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie | 196 | 443 | 88 | 88 | 169 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 18 | 5 | 0 | 0 | 0 |
| ARIH1 | ARIH1 | Q9Y4X5 | E3 ubiquitin-protein ligase ARIH1 | chr15 | Not Cancer Driver | No | 1 | hippie | 46 | 119 | 7 | 7 | 0 |
| ARL14EP | ARL14EP | Q8N8R7 | ARL14 effector protein | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 66 | 4 | 4 | 0 |
| ARNT | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | Census | Yes | 1 | hippie, biogrid | 77 | 511 | 56 | 56 | 0 |
| ASB13 | ASB13 | Q8WXK3 | Ankyrin repeat and SOCS box protein 13 | chr10 | Not Cancer Driver | No | 1 | hippie | 35 | 8 | 1 | 1 | 0 |
| ASB3 | ASB3 | Q9Y575 | Ankyrin repeat and SOCS box protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 71 | 0 | 0 | 0 | 0 |
| ASB8_ENST00000536549 | ASB8 | Q9H765 | Ankyrin repeat and SOCS box protein 8 | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 7 | 0 | 0 | 0 |
| ASTL | ASTL | Q6HA08 | Astacin-like metalloendopeptidase | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 101 | 179 | 44 | 44 | 0 |
| ATE1 | ATE1 | O95260 | Arginyl-tRNA--protein transferase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 53 | 189 | 22 | 22 | 0 |
| ATF7IP_ENST00000540793 | ATF7IP | Q6VMQ6 | Activating transcription factor 7-interacting protein 1 | chr12 | Compendium | Yes | 2 | hippie, biogrid | 160 | 1136 | 139 | 139 | 0 |
| ATIC | ATIC | P31939 | Bifunctional purine biosynthesis protein ATIC | chr2 | Census | Yes | 1 | intact, hippie | 74 | 25 | 1 | 1 | 1 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 469 | 225 | 39 | 39 | 41 |
| ATP5MF | ATP5MF | P56134 | ATP synthase subunit f, mitochondrial | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 0 | 0 | 0 | 0 |
| ATP5PB | ATP5PB | P24539 | ATP synthase F(0) complex subunit B1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 2 | 0 | 0 | 0 |
| ATP5PO | ATP5PO | P48047 | ATP synthase subunit O, mitochondrial | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 9 | 2 | 2 | 0 |
| ATXN2_ENST00000550104 | ATXN2 | Q99700 | Ataxin-2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 146 | 1228 | 134 | 134 | 0 |
| AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 178 | 21 | 21 | 0 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 14 | 26 | 0 | 0 | 39 |
| BACH1_ENST00000286800 | BACH1 | O14867 | Transcription regulator protein BACH1 | chr21 | Not Cancer Driver | No | 1 | hippie | 105 | 328 | 39 | 39 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | Not Cancer Driver | No | 1 | hippie | 42 | 130 | 17 | 17 | 0 |
| BCL2L14 | BCL2L14 | Q9BZR8 | Apoptosis facilitator Bcl-2-like protein 14 | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 29 | 40 | 4 | 4 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 139 | 26 | 26 | 0 |
| BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
| BSG | BSG | P35613 | Basigin | chr19 | Not Cancer Driver | No | 1 | hippie | 43 | 123 | 17 | 17 | 0 |
| BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
| C19orf70_ENST00000309324 | MICOS13 | Q5XKP0 | MICOS complex subunit MIC13 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 3 | 0 | 0 | 0 |
| C1QB | C1QB | P02746 | Complement C1q subcomponent subunit B | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 46 | 133 | 31 | 31 | 1 |
| C1QL4 | C1QL4 | Q86Z23 | Complement C1q-like protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 101 | 5 | 5 | 0 |
| C1QTNF1_ENST00000581774 | C1QTNF1 | Q9BXJ1 | Complement C1q tumor necrosis factor-related protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 96 | 17 | 17 | 0 |
| C1QTNF2 | C1QTNF2 | A0A499FIM1 | C1q and tumor necrosis factor related protein 2 | chr5 | Not Cancer Driver | No | 3 | hippie, biogrid | 58 | 169 | 38 | 38 | 0 |
| C1QTNF7_ENST00000429690 | C1QTNF7 | Q9BXJ2 | Complement C1q tumor necrosis factor-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 124 | 18 | 18 | 0 |
| C3 | C3 | P01024 | Complement C3 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 337 | 287 | 50 | 50 | 12 |
| CAB39 | CAB39 | Q9Y376 | Calcium-binding protein 39 | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 31 | 43 | 5 | 5 | 0 |
| CAD | CAD | P27708 | CAD protein | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 368 | 52 | 52 | 1 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 115 | 15 | 15 | 7 |
| CAPN7 | CAPN7 | Q9Y6W3 | Calpain-7 | chr3 | Not Cancer Driver | No | 1 | hippie | 80 | 92 | 9 | 9 | 0 |
| CAPZB_ENST00000375142 | CAPZB | P47756 | F-actin-capping protein subunit beta | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 66 | 3 | 3 | 0 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 225 | 35 | 35 | 11 |
| CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | Not Cancer Driver | No | 1 | hippie | 304 | 189 | 60 | 60 | 108 |
| CBR1 | CBR1 | P16152 | Carbonyl reductase [NADPH] 1 | chr21 | Not Cancer Driver | No | 1 | hippie | 27 | 62 | 11 | 11 | 0 |
| CBX1_ENST00000225603 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 31 | 154 | 25 | 25 | 0 |
| CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 119 | 18 | 18 | 0 |
| CBX5 | CBX5 | P45973 | Chromobox protein homolog 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 21 | 116 | 12 | 12 | 0 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 102 | 528 | 62 | 62 | 0 |
| CCDC59 | CCDC59 | Q9P031 | Thyroid transcription factor 1-associated protein 26 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 206 | 27 | 27 | 0 |
| CCDC82_ENST00000278520 | CCDC82 | Q8N4S0 | Coiled-coil domain-containing protein 82 | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 74 | 328 | 36 | 36 | 0 |
| CCIN | CCIN | Q13939 | Calicin | chr9 | Not Cancer Driver | No | 1 | hippie | 100 | 2 | 1 | 1 | 0 |
| CCNA1 | CCNA1 | P78396 | Cyclin-A1 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 112 | 82 | 21 | 21 | 0 |
| CCNC | CCNC | P24863 | Cyclin-C | chr6 | Census | Yes | 1 | hippie | 32 | 33 | 3 | 3 | 0 |
| CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 46 | 3 | 3 | 0 |
| CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 71 | 95 | 12 | 12 | 0 |
| CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 92 | 2 | 2 | 0 |
| CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 1 | hippie | 83 | 72 | 10 | 10 | 1 |
| CCT6A | CCT6A | P40227 | T-complex protein 1 subunit zeta | chr7 | Not Cancer Driver | No | 1 | hippie | 66 | 5 | 1 | 1 | 0 |
| CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 36 | 6 | 6 | 0 |
| CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | Not Cancer Driver | No | 1 | hippie | 41 | 36 | 2 | 2 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 542 | 60 | 60 | 0 |
| CDC34 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 95 | 11 | 11 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | hippie | 48 | 121 | 30 | 30 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | Census, Compendium | Yes | 1 | hippie | 19 | 198 | 19 | 19 | 0 |
| CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | Not Cancer Driver | No | 1 | hippie | 2 | 256 | 1 | 1 | 7 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | intact, hippie | 166 | 83 | 88 | 88 | 36 |
| CDO1 | CDO1 | Q16878 | Cysteine dioxygenase type 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 43 | 4 | 4 | 0 |
| CEP68 | CEP68 | Q76N32 | Centrosomal protein of 68 kDa | chr2 | Not Cancer Driver | No | 1 | hippie | 77 | 591 | 58 | 58 | 0 |
| CER1 | CER1 | O95813 | Cerberus | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 70 | 119 | 27 | 27 | 0 |
| CERKL | CERKL | Q49MI3 | Ceramide kinase-like protein | chr2 | Not Cancer Driver | No | 1 | hippie | 126 | 89 | 27 | 27 | 1 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | hippie | 335 | 157 | 130 | 130 | 13 |
| CHIT1 | CHIT1 | Q13231 | Chitotriosidase-1 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 86 | 85 | 11 | 11 | 0 |
| CHMP2B | CHMP2B | Q9UQN3 | Charged multivesicular body protein 2b | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 183 | 25 | 25 | 4 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | Not Cancer Driver | No | 1 | hippie | 69 | 156 | 27 | 27 | 0 |
| CMC2_ENST00000565650 | CMC2 | Q9NRP2 | COX assembly mitochondrial protein 2 homolog | chr16 | Not Cancer Driver | No | 1 | hippie | 9 | 37 | 5 | 5 | 0 |
| CNTF | CNTF | P26441 | Ciliary neurotrophic factor | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 41 | 34 | 5 | 5 | 0 |
| COL4A1 | COL4A1 | P02462 | Collagen alpha-1(IV) chain | chr13 | Not Cancer Driver | No | 1 | hippie | 349 | 1457 | 310 | 310 | 32 |
| COL4A2 | COL4A2 | P08572 | Collagen alpha-2(IV) chain | chr13 | Not Cancer Driver | No | 1 | hippie | 264 | 1462 | 234 | 234 | 2 |
| COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | Not Cancer Driver | No | 1 | hippie | 310 | 1433 | 277 | 277 | 13 |
| COL4A5_ENST00000361603 | COL4A5 | P29400 | Collagen alpha-5(IV) chain | chrX | Not Cancer Driver | No | 1 | hippie | 378 | 1459 | 327 | 327 | 144 |
| COL4A6_ENST00000372216 | COL4A6 | Q14031 | Collagen alpha-6(IV) chain | chrX | Not Cancer Driver | No | 1 | hippie | 286 | 1451 | 255 | 255 | 1 |
| COL6A1 | COL6A1 | P12109 | Collagen alpha-1(VI) chain | chr21 | Not Cancer Driver | No | 1 | hippie | 145 | 434 | 61 | 61 | 12 |
| COL9A1 | COL9A1 | P20849 | Collagen alpha-1(IX) chain | chr6 | Not Cancer Driver | No | 3 | hippie, biogrid | 262 | 722 | 201 | 201 | 0 |
| COLGALT1 | COLGALT1 | Q8NBJ5 | Procollagen galactosyltransferase 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 114 | 11 | 11 | 3 |
| COMP | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 306 | 52 | 52 | 61 |
| COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
| COTL1 | COTL1 | Q14019 | Coactosin-like protein | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 7 | 2 | 2 | 0 |
| COX5A | COX5A | P20674 | Cytochrome c oxidase subunit 5A, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 14 | 5 | 5 | 1 |
| CREB3 | CREB3 | O43889 | Cyclic AMP-responsive element-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 168 | 11 | 11 | 0 |
| CRTAP | CRTAP | O75718 | Cartilage-associated protein | chr3 | Not Cancer Driver | No | 1 | hippie | 29 | 0 | 0 | 0 | 3 |
| CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 71 | 75 | 8 | 8 | 4 |
| CSTA | CSTA | P01040 | Cystatin-A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 54 | 9 | 9 | 0 |
| CSTB | CSTB | P04080 | Cystatin-B | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 40 | 0 | 0 | 1 |
| CSTF3 | CSTF3 | Q12996 | Cleavage stimulation factor subunit 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 82 | 122 | 15 | 15 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
| CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 9 | intact, hippie, biogrid | 87 | 66 | 3 | 3 | 0 |
| CUL5 | CUL5 | Q93034 | Cullin-5 | chr11 | Not Cancer Driver | No | 1 | hippie | 97 | 5 | 1 | 1 | 0 |
| CUTA_ENST00000488034 | CUTA | O60888 | Protein CutA | chr6 | Not Cancer Driver | No | 1 | hippie | 16 | 15 | 3 | 3 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | Not Cancer Driver | No | 1 | hippie | 26 | 66 | 2 | 2 | 12 |
| CYCS_ENST00000409409 | CYCS | P99999 | Cytochrome c | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 19 | 3 | 3 | 1 |
| DACT1 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 163 | 598 | 127 | 127 | 1 |
| DACT2 | DACT2 | Q5SW24 | Dapper homolog 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 35 | 655 | 30 | 30 | 0 |
| DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 173 | 18 | 18 | 0 |
| DCAF8 | DCAF8 | Q5TAQ9 | DDB1- and CUL4-associated factor 8 | chr1 | Not Cancer Driver | No | 1 | hippie | 85 | 273 | 55 | 55 | 1 |
| DCTN1 | DCTN1 | Q14203 | Dynactin subunit 1 | chr2 | Census | Yes | 1 | intact, hippie | 172 | 817 | 111 | 111 | 11 |
| DCTPP1 | DCTPP1 | Q9H773 | dCTP pyrophosphatase 1 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 88 | 9 | 9 | 0 |
| DCUN1D1 | DCUN1D1 | Q96GG9 | DCN1-like protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
| DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | Census, Compendium | Yes | 1 | hippie | 45 | 70 | 5 | 5 | 2 |
| DDIT4 | DDIT4 | Q9NX09 | DNA damage-inducible transcript 4 protein | chr10 | Not Cancer Driver | No | 1 | hippie | 20 | 87 | 9 | 9 | 0 |
| DDT_ENST00000350608 | DDT | P30046 | D-dopachrome decarboxylase | chr22 | Not Cancer Driver | No | 1 | hippie | 4 | 0 | 0 | 0 | 0 |
| DDX17_ENST00000640332 | DDX17 | Q92841 | Probable ATP-dependent RNA helicase DDX17 | chr22 | Not Cancer Driver | No | 1 | hippie | 91 | 362 | 48 | 48 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | Census, Compendium | Yes | 1 | hippie | 133 | 301 | 47 | 47 | 18 |
| DDX3Y_ENST00000336079 | DDX3Y | O15523 | ATP-dependent RNA helicase DDX3Y | chrY | Not Cancer Driver | No | 1 | hippie | 31 | 289 | 18 | 18 | 0 |
| DDX5 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | Census | Yes | 1 | hippie | 74 | 225 | 23 | 23 | 0 |
| DGKI | DGKI | O75912 | Diacylglycerol kinase iota | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 243 | 355 | 62 | 62 | 0 |
| DGKZ_ENST00000456247 | DGKZ | Q13574 | Diacylglycerol kinase zeta | chr11 | Not Cancer Driver | No | 1 | hippie | 87 | 410 | 42 | 42 | 0 |
| DIRAS2 | DIRAS2 | Q96HU8 | GTP-binding protein Di-Ras2 | chr9 | Not Cancer Driver | No | 1 | hippie | 44 | 27 | 3 | 3 | 0 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 37 | 153 | 16 | 16 | 0 |
| DNAJA2 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 50 | 174 | 27 | 27 | 0 |
| DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 50 | 152 | 21 | 21 | 0 |
| DR1_ENST00000370267 | DR1 | Q01658 | Protein Dr1 | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 84 | 12 | 12 | 0 |
| DTL | DTL | Q9NZJ0 | Denticleless protein homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 331 | 49 | 49 | 0 |
| DTYMK | DTYMK | P23919 | Thymidylate kinase | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 10 | 0 | 0 | 0 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 96 | 514 | 64 | 64 | 0 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 272 | 23 | 23 | 0 |
| EAF2 | EAF2 | Q96CJ1 | ELL-associated factor 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 31 | 199 | 22 | 22 | 0 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 51 | 7 | 1 | 1 | 14 |
| ECM1_ENST00000369047 | ECM1 | Q16610 | Extracellular matrix protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 219 | 28 | 28 | 1 |
| EED_ENST00000263360 | EED | O75530 | Polycomb protein EED | chr11 | Census | Yes | 1 | hippie | 64 | 79 | 11 | 11 | 6 |
| EEF1B2_ENST00000236957 | EEF1B2 | P24534 | Elongation factor 1-beta | chr2 | Not Cancer Driver | No | 1 | hippie | 63 | 71 | 11 | 11 | 0 |
| EEF1D_ENST00000395119 | EEF1D | P29692 | Elongation factor 1-delta | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 153 | 22 | 22 | 0 |
| EGFL7_ENST00000308874 | EGFL7 | Q9UHF1 | Epidermal growth factor-like protein 7 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 36 | 2 | 2 | 0 |
| EGLN1 | EGLN1 | Q9GZT9 | Egl nine homolog 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 206 | 8 | 8 | 2 |
| EGLN2_ENST00000303961 | EGLN2 | Q96KS0 | Prolyl hydroxylase EGLN2 | chr19 | Not Cancer Driver | No | 1 | hippie | 52 | 201 | 17 | 17 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EIF1AX | EIF1AX | P47813 | Eukaryotic translation initiation factor 1A, X-chromosomal | chrX | Census, Compendium | Yes | 1 | hippie | 39 | 67 | 28 | 28 | 0 |
| EIF2B4_ENST00000347454 | EIF2B4 | Q9UI10 | Translation initiation factor eIF-2B subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 57 | 212 | 29 | 29 | 7 |
| EIF3K | EIF3K | Q9UBQ5 | Eukaryotic translation initiation factor 3 subunit K | chr19 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| EIF5A2 | EIF5A2 | Q9GZV4 | Eukaryotic translation initiation factor 5A-2 | chr3 | Not Cancer Driver | No | 1 | hippie | 20 | 28 | 4 | 4 | 0 |
| EIF5A_ENST00000419711 | EIF5A | P63241 | Eukaryotic translation initiation factor 5A-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 37 | 21 | 5 | 5 | 5 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| ELOA2 | ELOA2 | Q8IYF1 | Elongin-A2 | chr18 | Not Cancer Driver | No | 1 | hippie | 232 | 717 | 222 | 222 | 0 |
| ELOA_ENST00000613537 | ELOA | Q14241 | Elongin-A | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 652 | 62 | 62 | 0 |
| ELOB_ENST00000409906 | ELOB | Q15370 | Elongin-B | chr16 | Not Cancer Driver | No | 9 | intact, hippie | 13 | 69 | 10 | 10 | 0 |
| ELOC | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 6 | intact, hippie | 22 | 25 | 5 | 5 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
| EPAS1 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | Census, Compendium | Yes | 4 | intact, hippie, biogrid | 120 | 449 | 53 | 53 | 6 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 140 | 24 | 24 | 0 |
| EPOR | EPOR | P19235 | Erythropoietin receptor | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 120 | 11 | 11 | 1 |
| EXOSC8 | EXOSC8 | Q96B26 | Exosome complex component RRP43 | chr13 | Not Cancer Driver | No | 1 | hippie | 20 | 28 | 1 | 1 | 2 |
| EZR | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | intact, hippie | 66 | 295 | 35 | 35 | 0 |
| FABP5 | FABP5 | Q01469 | Fatty acid-binding protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 15 | 4 | 4 | 4 | 0 |
| FAM19A3_ENST00000361886 | TAFA3 | Q7Z5A8 | Chemokine-like protein TAFA-3 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 6 | 0 | 0 | 0 |
| FASN | FASN | P49327 | Fatty acid synthase | chr17 | Not Cancer Driver | No | 1 | hippie | 291 | 309 | 42 | 42 | 0 |
| FASTKD3 | FASTKD3 | Q14CZ7 | FAST kinase domain-containing protein 3, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 106 | 6 | 1 | 1 | 0 |
| FKBP1A | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 39 | 7 | 7 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie | 71 | 160 | 25 | 25 | 0 |
| FLG | FLG | P20930 | Filaggrin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 1612 | 3956 | 1593 | 1593 | 0 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | Census | Yes | 1 | hippie | 416 | 1456 | 214 | 214 | 28 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 2 | intact, hippie | 394 | 1243 | 185 | 185 | 8 |
| FSCN1 | FSCN1 | Q16658 | Fascin | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 58 | 81 | 5 | 5 | 0 |
| FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
| G6PD_ENST00000621232 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | Not Cancer Driver | No | 1 | hippie | 86 | 28 | 3 | 3 | 58 |
| GAN | GAN | Q9H2C0 | Gigaxonin | chr16 | Not Cancer Driver | No | 1 | hippie | 74 | 33 | 6 | 6 | 19 |
| GDI2 | GDI2 | P50395 | Rab GDP dissociation inhibitor beta | chr10 | Not Cancer Driver | No | 1 | hippie | 49 | 23 | 2 | 2 | 0 |
| GLI1 | GLI1 | P08151 | Zinc finger protein GLI1 | chr12 | Census, Compendium | Yes | 1 | intact, hippie | 206 | 1015 | 184 | 184 | 0 |
| GLRX5 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 7 | 23 | 0 | 0 | 2 |
| GNB2 | GNB2 | P62879 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 50 | 21 | 0 | 0 | 7 |
| GOLGA4_ENST00000361924 | GOLGA4 | Q13439 | Golgin subfamily A member 4 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 231 | 1658 | 162 | 162 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | Not Cancer Driver | No | 1 | hippie | 153 | 36 | 9 | 9 | 0 |
| GPS1_ENST00000306823 | GPS1 | Q13098 | COP9 signalosome complex subunit 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 62 | 106 | 14 | 14 | 0 |
| GRN | GRN | P28799 | Progranulin | chr17 | Not Cancer Driver | No | 1 | hippie | 76 | 29 | 6 | 6 | 1 |
| GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 22 | 88 | 7 | 7 | 0 |
| GRWD1 | GRWD1 | Q9BQ67 | Glutamate-rich WD repeat-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 44 | 187 | 14 | 14 | 0 |
| GSPT1_ENST00000563468 | GSPT1 | P15170 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A | chr16 | Not Cancer Driver | No | 1 | hippie | 42 | 149 | 13 | 13 | 0 |
| GTF3C3 | GTF3C3 | Q9Y5Q9 | General transcription factor 3C polypeptide 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 109 | 195 | 22 | 22 | 0 |
| HAS1 | HAS1 | Q92839 | Hyaluronan synthase 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 9 | 0 | 0 | 0 |
| HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
| HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 14 | 14 | 0 |
| HDAC3 | HDAC3 | O15379 | Histone deacetylase 3 | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 61 | 8 | 8 | 0 |
| HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | Census | Yes | 3 | hippie, biogrid | 118 | 435 | 51 | 51 | 0 |
| HIF3A | HIF3A | Q9Y2N7 | Hypoxia-inducible factor 3-alpha | chr19 | Not Cancer Driver | No | 1 | hippie | 146 | 361 | 94 | 94 | 0 |
| HINT1 | HINT1 | P49773 | Adenosine 5'-monophosphoramidase HINT1 | chr5 | Not Cancer Driver | No | 1 | hippie | 11 | 6 | 0 | 0 | 6 |
| HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie | 70 | 290 | 58 | 58 | 4 |
| HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | hippie | 68 | 255 | 41 | 41 | 0 |
| HNRNPA3 | HNRNPA3 | P51991 | Heterogeneous nuclear ribonucleoprotein A3 | chr2 | Not Cancer Driver | No | 1 | hippie | 46 | 285 | 37 | 37 | 0 |
| HNRNPAB | HNRNPAB | Q99729 | Heterogeneous nuclear ribonucleoprotein A/B | chr5 | Not Cancer Driver | No | 1 | hippie | 31 | 202 | 11 | 11 | 0 |
| HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | Not Cancer Driver | No | 1 | hippie | 42 | 227 | 35 | 35 | 0 |
| HNRNPD | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | Not Cancer Driver | No | 1 | hippie | 39 | 206 | 19 | 19 | 0 |
| HNRNPDL | HNRNPDL | O14979 | Heterogeneous nuclear ribonucleoprotein D-like | chr4 | Not Cancer Driver | No | 1 | hippie | 51 | 297 | 36 | 36 | 2 |
| HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
| HNRNPH2 | HNRNPH2 | P55795 | Heterogeneous nuclear ribonucleoprotein H2 | chrX | Not Cancer Driver | No | 1 | hippie | 73 | 168 | 34 | 34 | 3 |
| HNRNPK_ENST00000351839 | HNRNPK | P61978 | Heterogeneous nuclear ribonucleoprotein K | chr9 | Not Cancer Driver | No | 1 | hippie | 75 | 302 | 59 | 59 | 0 |
| HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
| HNRNPLL | HNRNPLL | Q8WVV9 | Heterogeneous nuclear ribonucleoprotein L-like | chr2 | Not Cancer Driver | No | 1 | hippie | 37 | 149 | 13 | 13 | 0 |
| HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | hippie | 108 | 463 | 67 | 67 | 0 |
| HNRNPR_ENST00000374612 | HNRNPR | O43390 | Heterogeneous nuclear ribonucleoprotein R | chr1 | Not Cancer Driver | No | 1 | hippie | 67 | 304 | 25 | 25 | 0 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 504 | 45 | 45 | 0 |
| HPRT1 | HPRT1 | P00492 | Hypoxanthine-guanine phosphoribosyltransferase | chrX | Not Cancer Driver | No | 1 | intact, hippie | 22 | 3 | 0 | 0 | 62 |
| HSF2BP | HSF2BP | O75031 | Heat shock factor 2-binding protein | chr21 | Not Cancer Driver | No | 1 | hippie | 52 | 23 | 3 | 3 | 1 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 106 | 257 | 37 | 37 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 200 | 13 | 13 | 0 |
| HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 351 | 24 | 24 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
| HSPB11 | HSPB11 | Q9Y547 | Intraflagellar transport protein 25 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 20 | 27 | 2 | 2 | 0 |
| HSPE1 | HSPE1 | P61604 | 10 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 3 | 0 | 0 | 0 |
| HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | hippie | 336 | 666 | 69 | 69 | 2 |
| HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
| HYOU1 | HYOU1 | Q9Y4L1 | Hypoxia up-regulated protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 132 | 373 | 47 | 47 | 0 |
| ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | Not Cancer Driver | No | 1 | hippie | 20 | 17 | 6 | 6 | 0 |
| ID2_ENST00000396290 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | Not Cancer Driver | No | 1 | hippie | 14 | 52 | 7 | 7 | 0 |
| ID3 | ID3 | Q02535 | DNA-binding protein inhibitor ID-3 | chr1 | Census, Compendium | Yes | 1 | hippie | 14 | 34 | 4 | 4 | 0 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | Census, Compendium | Yes | 1 | hippie | 106 | 211 | 31 | 31 | 1 |
| IL32 | IL32 | P24001 | Interleukin-32 | chr16 | Not Cancer Driver | No | 1 | hippie | 41 | 70 | 17 | 17 | 0 |
| ILF3_ENST00000590261 | ILF3 | Q12906 | Interleukin enhancer-binding factor 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 103 | 674 | 82 | 82 | 0 |
| IMPDH2 | IMPDH2 | P12268 | Inosine-5'-monophosphate dehydrogenase 2 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 70 | 6 | 1 | 1 | 0 |
| INHBE | INHBE | P58166 | Inhibin beta E chain | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 85 | 12 | 12 | 0 |
| IREB2 | IREB2 | P48200 | Iron-responsive element-binding protein 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 126 | 107 | 13 | 13 | 0 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 166 | 26 | 0 | 0 | 0 |
| ITGA3 | ITGA3 | P26006 | Integrin alpha-3 | chr17 | Not Cancer Driver | No | 1 | hippie | 106 | 129 | 18 | 18 | 3 |
| ITGA5 | ITGA5 | P08648 | Integrin alpha-5 | chr12 | Not Cancer Driver | No | 1 | hippie | 127 | 201 | 29 | 29 | 0 |
| ITGAL | ITGAL | P20701 | Integrin alpha-L | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 196 | 144 | 25 | 25 | 0 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 103 | 84 | 10 | 10 | 0 |
| IVNS1ABP | IVNS1ABP | Q9Y6Y0 | Influenza virus NS1A-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 85 | 90 | 12 | 12 | 0 |
| JADE1_ENST00000512960 | JADE1 | Q6IE81 | Protein Jade-1 | chr4 | Not Cancer Driver | No | 2 | intact, hippie | 94 | 409 | 47 | 47 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | Census, Compendium | Yes | 1 | hippie | 136 | 59 | 5 | 5 | 5 |
| JMJD1C | JMJD1C | Q15652 | Probable JmjC domain-containing histone demethylation protein 2C | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 305 | 1640 | 200 | 200 | 0 |
| JPH3 | JPH3 | Q8WXH2 | Junctophilin-3 | chr16 | Not Cancer Driver | No | 1 | hippie | 130 | 534 | 92 | 92 | 0 |
| JUP | JUP | P14923 | Junction plakoglobin | chr17 | Not Cancer Driver | No | 1 | hippie | 112 | 241 | 37 | 37 | 0 |
| KAT2A | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | Not Cancer Driver | No | 1 | hippie | 88 | 251 | 17 | 17 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
| KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | Not Cancer Driver | No | 1 | hippie | 65 | 173 | 21 | 21 | 3 |
| KATNB1 | KATNB1 | Q9BVA0 | Katanin p80 WD40 repeat-containing subunit B1 | chr16 | Not Cancer Driver | No | 1 | hippie | 70 | 179 | 24 | 24 | 3 |
| KIF1B_ENST00000377086 | KIF1B | O60333 | Kinesin-like protein KIF1B | chr1 | Not Cancer Driver | No | 1 | hippie | 253 | 633 | 106 | 106 | 1 |
| KIF2C | KIF2C | Q99661 | Kinesin-like protein KIF2C | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 337 | 63 | 63 | 0 |
| KIF3A_ENST00000378746 | KIF3A | Q9Y496 | Kinesin-like protein KIF3A | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 409 | 59 | 59 | 0 |
| KIF3B | KIF3B | O15066 | Kinesin-like protein KIF3B | chr20 | Not Cancer Driver | No | 1 | hippie | 105 | 485 | 69 | 69 | 2 |
| KIF5B | KIF5B | P33176 | Kinesin-1 heavy chain | chr10 | Census, Compendium | Yes | 1 | intact, hippie | 122 | 586 | 67 | 67 | 0 |
| KIFAP3 | KIFAP3 | Q92845 | Kinesin-associated protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 116 | 71 | 10 | 10 | 0 |
| KIRREL2 | KIRREL2 | Q6UWL6 | Kin of IRRE-like protein 2 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 139 | 303 | 68 | 68 | 0 |
| KLF4 | KLF4 | O43474-1 | Isoform 2 of Krueppel-like factor 4 | chr9 | Census, Compendium | Yes | 1 | hippie | 58 | 415 | 38 | 38 | 0 |
| KLHL1 | KLHL1 | Q9NR64 | Kelch-like protein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 253 | 217 | 66 | 66 | 0 |
| KLHL12 | KLHL12 | Q53G59 | Kelch-like protein 12 | chr1 | Not Cancer Driver | No | 1 | hippie | 65 | 33 | 6 | 6 | 0 |
| KLHL17 | KLHL17 | Q6TDP4 | Kelch-like protein 17 | chr1 | Not Cancer Driver | No | 1 | hippie | 60 | 135 | 5 | 5 | 0 |
| KLHL23_ENST00000272797 | KLHL23 | Q8NBE8 | Kelch-like protein 23 | chr2 | Not Cancer Driver | No | 1 | hippie | 81 | 0 | 0 | 0 | 0 |
| KLHL41 | KLHL41 | O60662 | Kelch-like protein 41 | chr2 | Not Cancer Driver | No | 1 | hippie | 69 | 18 | 2 | 2 | 1 |
| KLHL7 | KLHL7 | Q8IXQ5 | Kelch-like protein 7 | chr7 | Not Cancer Driver | No | 1 | hippie | 85 | 31 | 4 | 4 | 6 |
| KNG1 | KNG1 | P01042 | Kininogen-1 | chr3 | Not Cancer Driver | No | 3 | hippie, biogrid | 130 | 294 | 66 | 66 | 1 |
| KNTC1 | KNTC1 | P50748 | Kinetochore-associated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 250 | 70 | 9 | 9 | 0 |
| KRTCAP2 | KRTCAP2 | Q8N6L1-2 | Isoform 2 of Keratinocyte-associated protein 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 16 | 4 | 2 | 2 | 0 |
| LAIR2 | LAIR2 | Q6ISS4 | Leukocyte-associated immunoglobulin-like receptor 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 77 | 26 | 26 | 0 |
| LANCL1_ENST00000450366 | LANCL1 | O43813 | Glutathione S-transferase LANCL1 | chr2 | Not Cancer Driver | No | 1 | hippie | 45 | 10 | 0 | 0 | 0 |
| LGALS3BP | LGALS3BP | Q08380 | Galectin-3-binding protein | chr17 | Not Cancer Driver | No | 1 | hippie | 62 | 9 | 0 | 0 | 0 |
| LIMD1 | LIMD1 | Q9UGP4 | LIM domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 58 | 428 | 36 | 36 | 0 |
| LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 222 | 25 | 25 | 1 |
| LPP_ENST00000617246 | LPP | Q93052 | Lipoma-preferred partner | chr3 | Census, Compendium | Yes | 1 | hippie | 108 | 408 | 61 | 61 | 0 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 122 | 15 | 15 | 0 |
| LSM12 | LSM12 | Q3MHD2 | Protein LSM12 homolog | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 66 | 7 | 7 | 0 |
| LTV1 | LTV1 | Q96GA3 | Protein LTV1 homolog | chr6 | Not Cancer Driver | No | 1 | hippie | 45 | 388 | 30 | 30 | 0 |
| LYPLA1 | LYPLA1 | O75608 | Acyl-protein thioesterase 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 19 | 12 | 2 | 2 | 0 |
| LYZ | LYZ | P61626 | Lysozyme C | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 0 | 0 | 0 | 2 |
| MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | Census, Compendium | Yes | 1 | hippie | 75 | 139 | 12 | 12 | 1 |
| MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 17 | 1 | 1 | 0 |
| MARVELD2_ENST00000325631 | MARVELD2 | Q8N4S9 | MARVEL domain-containing protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 74 | 251 | 36 | 36 | 0 |
| MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 136 | 589 | 92 | 92 | 0 |
| MCM7 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 128 | 22 | 22 | 0 |
| MCTS1_ENST00000371317 | MCTS1 | Q9ULC4 | Malignant T-cell-amplified sequence 1 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 34 | 0 | 0 | 0 | 0 |
| MDFI | MDFI | Q99750 | MyoD family inhibitor | chr6 | Not Cancer Driver | No | 1 | hippie | 25 | 152 | 15 | 15 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 4 | 0 | 0 | 0 | 0 |
| MKNK2_ENST00000591601 | MKNK2 | Q9HBH9 | MAP kinase-interacting serine/threonine-protein kinase 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 42 | 124 | 8 | 8 | 0 |
| MOB4 | MOB4 | Q9Y3A3 | MOB-like protein phocein | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 23 | 34 | 5 | 5 | 0 |
| MRPL14 | MRPL14 | Q6P1L8 | 39S ribosomal protein L14, mitochondrial | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 36 | 6 | 6 | 0 |
| MRPL58 | MRPL58 | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 28 | 105 | 13 | 13 | 0 |
| MRPS16 | MRPS16 | Q9Y3D3 | 28S ribosomal protein S16, mitochondrial | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 7 | 29 | 2 | 2 | 0 |
| MRPS23 | MRPS23 | Q9Y3D9 | 28S ribosomal protein S23, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 58 | 6 | 6 | 1 |
| MSH4 | MSH4 | O15457 | MutS protein homolog 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 199 | 196 | 42 | 42 | 0 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | Census, Compendium | Yes | 1 | hippie | 379 | 296 | 37 | 37 | 18 |
| MTPN | MTPN | P58546 | Myotrophin | chr7 | Not Cancer Driver | No | 1 | hippie | 11 | 11 | 3 | 3 | 0 |
| MYBBP1A_ENST00000254718 | MYBBP1A | Q9BQG0 | Myb-binding protein 1A | chr17 | Not Cancer Driver | No | 1 | hippie | 144 | 463 | 47 | 47 | 0 |
| MYCBP | MYCBP | Q99417 | c-Myc-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 8 | 54 | 4 | 4 | 0 |
| MYCBPAP_ENST00000436259 | MYCBPAP | Q8TBZ2 | MYCBP-associated protein | chr17 | Not Cancer Driver | No | 1 | hippie | 144 | 534 | 81 | 81 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| MYDGF | MYDGF | Q969H8 | Myeloid-derived growth factor | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 26 | 4 | 4 | 0 |
| MYL12A_ENST00000217652 | MYL12A | P19105 | Myosin regulatory light chain 12A | chr18 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 19 | 70 | 13 | 13 | 0 |
| MYL6_ENST00000548293 | MYL6 | P60660 | Myosin light polypeptide 6 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 17 | 1 | 1 | 0 |
| NACC2_ENST00000371753 | NACC2 | Q96BF6 | Nucleus accumbens-associated protein 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 24 | 238 | 10 | 10 | 0 |
| NCL | NCL | P19338 | Nucleolin | chr2 | Not Cancer Driver | No | 1 | hippie | 85 | 569 | 68 | 68 | 0 |
| NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 36 | 5 | 5 | 0 |
| NEK8 | NEK8 | Q86SG6 | Serine/threonine-protein kinase Nek8 | chr17 | Not Cancer Driver | No | 1 | hippie | 102 | 167 | 40 | 40 | 3 |
| NF2 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 69 | 252 | 26 | 26 | 16 |
| NKRF_ENST00000304449 | NKRF | O15226 | NF-kappa-B-repressing factor | chrX | Not Cancer Driver | No | 1 | hippie | 100 | 366 | 49 | 49 | 0 |
| NME4 | NME4 | O00746 | Nucleoside diphosphate kinase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 13 | 41 | 4 | 4 | 0 |
| NOB1 | NOB1 | Q9ULX3 | RNA-binding protein NOB1 | chr16 | Not Cancer Driver | No | 1 | hippie | 38 | 185 | 15 | 15 | 0 |
| NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 362 | 37 | 37 | 12 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 62 | 252 | 24 | 24 | 0 |
| NUDC | NUDC | Q9Y266 | Nuclear migration protein nudC | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 235 | 29 | 29 | 0 |
| NUDT21 | NUDT21 | O43809 | Cleavage and polyadenylation specificity factor subunit 5 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 37 | 3 | 3 | 0 |
| NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie | 154 | 221 | 19 | 19 | 1 |
| OR6K3_ENST00000368146 | OR6K3 | Q8NGY3 | Olfactory receptor 6K3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 132 | 6 | 2 | 2 | 0 |
| OSR1 | OSR1 | Q8TAX0 | Protein odd-skipped-related 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 57 | 67 | 17 | 17 | 0 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 33 | 2 | 2 | 0 |
| OTUD6B_ENST00000404789 | OTUD6B | Q8N6M0 | Deubiquitinase OTUD6B | chr8 | Not Cancer Driver | No | 1 | hippie | 35 | 152 | 18 | 18 | 0 |
| OTUD7A | OTUD7A | Q8TE49 | OTU domain-containing protein 7A | chr15 | Not Cancer Driver | No | 1 | hippie | 121 | 591 | 65 | 65 | 0 |
| OXT | OXT | P01178 | Oxytocin-neurophysin 1 | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 10 | 0 | 0 | 0 | 0 |
| P3H1_ENST00000296388 | P3H1 | Q32P28 | Prolyl 3-hydroxylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 91 | 177 | 18 | 18 | 0 |
| P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 79 | 15 | 15 | 1 |
| PAPSS2_ENST00000361175 | PAPSS2 | O95340 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 100 | 7 | 7 | 4 |
| PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | Not Cancer Driver | No | 1 | hippie | 200 | 1144 | 170 | 170 | 2 |
| PARD6A | PARD6A | Q9NPB6 | Partitioning defective 6 homolog alpha | chr16 | Not Cancer Driver | No | 1 | hippie | 25 | 177 | 13 | 13 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 30 | 0 | 0 | 5 |
| PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 119 | 320 | 34 | 34 | 0 |
| PCBP1 | PCBP1 | Q15365 | Poly(rC)-binding protein 1 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 65 | 166 | 24 | 24 | 0 |
| PCMT1_ENST00000464889 | PCMT1 | A0A0A0MRJ6 | Protein-L-isoaspartate O-methyltransferase | chr6 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 34 | 38 | 4 | 4 | 0 |
| PCMTD2 | PCMTD2 | Q9NV79 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 55 | 75 | 17 | 17 | 0 |
| PDCD5 | PDCD5 | O14737 | Programmed cell death protein 5 | chr19 | Not Cancer Driver | No | 1 | hippie | 15 | 91 | 7 | 7 | 0 |
| PEBP1 | PEBP1 | P30086 | Phosphatidylethanolamine-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 76 | 13 | 13 | 0 |
| PFAS | PFAS | O15067 | Phosphoribosylformylglycinamidine synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 380 | 36 | 36 | 0 |
| PFDN1 | PFDN1 | O60925 | Prefoldin subunit 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 42 | 4 | 4 | 0 |
| PFDN2 | PFDN2 | Q9UHV9 | Prefoldin subunit 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 111 | 11 | 11 | 0 |
| PFDN4 | PFDN4 | Q9NQP4 | Prefoldin subunit 4 | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 40 | 6 | 6 | 0 |
| PFDN5 | PFDN5 | Q99471 | Prefoldin subunit 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 3 | 0 | 0 | 0 |
| PFDN6_ENST00000374610 | PFDN6 | O15212 | Prefoldin subunit 6 | chr6 | Not Cancer Driver | No | 1 | hippie | 14 | 57 | 8 | 8 | 0 |
| PFN2 | PFN2 | P35080 | Profilin-2 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 0 | 0 | 0 | 0 |
| PGRMC1 | PGRMC1 | O00264 | Membrane-associated progesterone receptor component 1 | chrX | Not Cancer Driver | No | 1 | hippie | 30 | 74 | 16 | 16 | 0 |
| PHIP | PHIP | Q8WWQ0 | PH-interacting protein | chr6 | Not Cancer Driver | No | 1 | hippie | 239 | 835 | 110 | 110 | 0 |
| PHOSPHO2_ENST00000616481 | PHOSPHO2 | Q8TCD6 | Pyridoxal phosphate phosphatase PHOSPHO2 | chr2 | Not Cancer Driver | No | 1 | hippie | 38 | 0 | 0 | 0 | 0 |
| PIAS4 | PIAS4 | Q8N2W9 | E3 SUMO-protein ligase PIAS4 | chr19 | Not Cancer Driver | No | 1 | hippie | 58 | 142 | 23 | 23 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 115 | 12 | 12 | 0 |
| PITPNB_ENST00000335272 | PITPNB | P48739 | Phosphatidylinositol transfer protein beta isoform | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 69 | 2 | 2 | 0 |
| PKD1L3 | PKD1L3 | Q7Z443 | Polycystic kidney disease protein 1-like 3 | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 97 | 145 | 9 | 9 | 0 |
| PLD1 | PLD1 | Q13393 | Phospholipase D1 | chr3 | Not Cancer Driver | No | 1 | hippie | 181 | 133 | 32 | 32 | 1 |
| PLD2 | PLD2 | O14939 | Phospholipase D2 | chr17 | Not Cancer Driver | No | 1 | hippie | 107 | 97 | 8 | 8 | 0 |
| PLOD2_ENST00000360060 | PLOD2 | O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 109 | 17 | 3 | 3 | 4 |
| PLOD3 | PLOD3 | O60568 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 | chr7 | Not Cancer Driver | No | 1 | hippie | 108 | 65 | 8 | 8 | 1 |
| PLP2 | PLP2 | Q04941 | Proteolipid protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 40 | 10 | 3 | 3 | 0 |
| PLS3_ENST00000539310 | PLS3 | P13797 | Plastin-3 | chrX | Not Cancer Driver | No | 1 | hippie | 75 | 75 | 5 | 5 | 0 |
| POLR2A | POLR2A | P24928-2 | Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 | chr17 | Census | Yes | 1 | hippie | 56 | 230 | 20 | 20 | 0 |
| POLR2D | POLR2D | O15514 | DNA-directed RNA polymerase II subunit RPB4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 54 | 2 | 2 | 0 |
| POLR2G | POLR2G | P62487 | DNA-directed RNA polymerase II subunit RPB7 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 15 | 15 | 1 | 1 | 0 |
| POLR2I | POLR2I | P36954 | DNA-directed RNA polymerase II subunit RPB9 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 22 | 5 | 5 | 0 |
| PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | Not Cancer Driver | No | 1 | hippie | 63 | 68 | 9 | 9 | 0 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | Not Cancer Driver | No | 1 | hippie | 72 | 69 | 7 | 7 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | Census | Yes | 1 | hippie | 72 | 44 | 4 | 4 | 3 |
| PPIB | PPIB | P23284 | Peptidyl-prolyl cis-trans isomerase B | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 28 | 16 | 1 | 1 | 1 |
| PPM1B | PPM1B | O75688 | Protein phosphatase 1B | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 243 | 31 | 31 | 0 |
| PPP2CA | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | Not Cancer Driver | No | 1 | hippie | 41 | 12 | 1 | 1 | 8 |
| PPP2R2B_ENST00000394409 | PPP2R2B | Q00005 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform | chr5 | Not Cancer Driver | No | 1 | hippie | 101 | 76 | 22 | 22 | 0 |
| PPP5C | PPP5C | P53041 | Serine/threonine-protein phosphatase 5 | chr19 | Not Cancer Driver | No | 1 | hippie | 70 | 73 | 12 | 12 | 0 |
| PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 40 | 5 | 5 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | Compendium | Yes | 1 | hippie | 79 | 43 | 9 | 9 | 0 |
| PRKCH | PRKCH | P24723 | Protein kinase C eta type | chr14 | Not Cancer Driver | No | 1 | hippie | 89 | 92 | 13 | 13 | 0 |
| PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | Not Cancer Driver | No | 1 | hippie | 110 | 120 | 16 | 16 | 0 |
| PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 70 | 116 | 11 | 11 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
| PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 18 | 1 | 1 | 0 |
| PRMT3 | PRMT3 | O60678 | Protein arginine N-methyltransferase 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 68 | 52 | 9 | 9 | 0 |
| PRMT5 | PRMT5 | O14744 | Protein arginine N-methyltransferase 5 | chr14 | Not Cancer Driver | No | 1 | hippie | 83 | 72 | 6 | 6 | 0 |
| PRMT8 | PRMT8 | Q9NR22 | Protein arginine N-methyltransferase 8 | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 61 | 16 | 16 | 0 |
| PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 0 | 0 | 0 | 0 |
| PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 2 | 1 | 1 | 0 |
| PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
| PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 9 | 0 | 0 | 0 |
| PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 1 | hippie | 55 | 131 | 10 | 10 | 0 |
| PSMD13_ENST00000532097 | PSMD13 | Q9UNM6 | 26S proteasome non-ATPase regulatory subunit 13 | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 30 | 13 | 3 | 3 | 0 |
| PSMD2 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 100 | 135 | 14 | 14 | 0 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 11 | 52 | 3 | 3 | 0 |
| PTMA | PTMA | P06454 | Prothymosin alpha | chr2 | Compendium | Yes | 1 | intact, hippie | 10 | 111 | 10 | 10 | 0 |
| PTPN14 | PTPN14 | Q15678 | Tyrosine-protein phosphatase non-receptor type 14 | chr1 | Compendium | Yes | 1 | hippie | 173 | 582 | 99 | 99 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 43 | 4 | 4 | 0 |
| RAB14 | RAB14 | P61106 | Ras-related protein Rab-14 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 41 | 4 | 4 | 0 |
| RAB1B | RAB1B | Q9H0U4 | Ras-related protein Rab-1B | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 24 | 40 | 3 | 3 | 0 |
| RAB2A | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 58 | 4 | 4 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 25 | 2 | 2 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 50 | 4 | 4 | 0 |
| RAB6A_ENST00000336083 | RAB6A | P20340 | Ras-related protein Rab-6A | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 45 | 6 | 6 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 11 | 0 | 0 | 4 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
| RALBP1 | RALBP1 | Q15311 | RalA-binding protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 65 | 381 | 46 | 46 | 0 |
| RALYL_ENST00000521268 | RALYL | Q86SE5 | RNA-binding Raly-like protein | chr8 | Not Cancer Driver | No | 1 | hippie | 111 | 181 | 75 | 75 | 0 |
| RANBP1_ENST00000331821 | RANBP1 | P43487 | Ran-specific GTPase-activating protein | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 137 | 16 | 16 | 0 |
| RAP1A_ENST00000356415 | RAP1A | P62834 | Ras-related protein Rap-1A | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 5 | 0 | 0 | 0 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 191 | 12 | 12 | 1 |
| RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
| RBBP4 | RBBP4 | Q09028 | Histone-binding protein RBBP4 | chr1 | Not Cancer Driver | No | 1 | hippie | 53 | 169 | 23 | 23 | 0 |
| RBBP7_ENST00000380087 | RBBP7 | Q16576 | Histone-binding protein RBBP7 | chrX | Not Cancer Driver | No | 1 | hippie | 67 | 138 | 19 | 19 | 0 |
| RBPMS2 | RBPMS2 | Q6ZRY4 | RNA-binding protein with multiple splicing 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 24 | 55 | 4 | 4 | 0 |
| RBPMS_ENST00000320203 | RBPMS | Q93062 | RNA-binding protein with multiple splicing | chr8 | Not Cancer Driver | No | 1 | hippie | 23 | 87 | 11 | 11 | 0 |
| RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 10 | 18 | 1 | 1 | 0 |
| RCC2 | RCC2 | Q9P258 | Protein RCC2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 194 | 27 | 27 | 0 |
| RETNLB | RETNLB | Q9BQ08 | Resistin-like beta | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| RHOBTB3 | RHOBTB3 | O94955 | Rho-related BTB domain-containing protein 3 | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 34 | 2 | 2 | 0 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 53 | 7 | 7 | 0 |
| RHPN2 | RHPN2 | Q8IUC4 | Rhophilin-2 | chr19 | Compendium | Yes | 1 | hippie | 111 | 88 | 17 | 17 | 0 |
| RIT1_ENST00000368323 | RIT1 | Q92963 | GTP-binding protein Rit1 | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 43 | 3 | 3 | 5 |
| RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 76 | 7 | 7 | 0 |
| RNF139 | RNF139 | Q8WU17 | E3 ubiquitin-protein ligase RNF139 | chr8 | Not Cancer Driver | No | 1 | hippie | 76 | 68 | 4 | 4 | 0 |
| RNF7 | RNF7 | Q9UBF6 | RING-box protein 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 17 | 0 | 0 | 0 | 0 |
| RPA3 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 4 | 1 | 1 | 0 |
| RPL10A | RPL10A | P62906 | 60S ribosomal protein L10a | chr6 | Not Cancer Driver | No | 1 | hippie | 22 | 16 | 0 | 0 | 0 |
| RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 12 | 1 | 1 | 1 |
| RPL12 | RPL12 | P30050 | 60S ribosomal protein L12 | chr9 | Not Cancer Driver | No | 1 | hippie | 13 | 75 | 6 | 6 | 0 |
| RPL14_ENST00000396203 | RPL14 | P50914 | 60S ribosomal protein L14 | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 129 | 13 | 13 | 0 |
| RPL18A | RPL18A | Q02543 | 60S ribosomal protein L18a | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 28 | 25 | 4 | 4 | 0 |
| RPL21_ENST00000326092 | RPL21 | P46778 | 60S ribosomal protein L21 | chr13 | Not Cancer Driver | No | 1 | hippie | 15 | 103 | 11 | 11 | 1 |
| RPL22 | RPL22 | P35268 | 60S ribosomal protein L22 | chr1 | Census, Compendium | Yes | 1 | intact, hippie | 26 | 15 | 1 | 1 | 0 |
| RPL23A | RPL23A | P62750 | 60S ribosomal protein L23a | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 70 | 13 | 13 | 0 |
| RPL29_ENST00000475248 | RPL29 | P47914 | 60S ribosomal protein L29 | chr3 | Not Cancer Driver | No | 1 | hippie | 9 | 159 | 9 | 9 | 0 |
| RPL30 | RPL30 | P62888 | 60S ribosomal protein L30 | chr8 | Not Cancer Driver | No | 1 | hippie | 4 | 11 | 0 | 0 | 0 |
| RPL35 | RPL35 | P42766 | 60S ribosomal protein L35 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 65 | 9 | 9 | 0 |
| RPL37A | RPL37A | P61513 | 60S ribosomal protein L37a | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 4 | 0 | 0 | 0 | 0 |
| RPL5_ENST00000370321 | RPL5 | P46777 | 60S ribosomal protein L5 | chr1 | Census | Yes | 1 | hippie | 57 | 96 | 17 | 17 | 2 |
| RPL6 | RPL6 | Q02878 | 60S ribosomal protein L6 | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 159 | 24 | 24 | 0 |
| RPL7A | RPL7A | P62424 | 60S ribosomal protein L7a | chr9 | Not Cancer Driver | No | 1 | hippie | 27 | 100 | 5 | 5 | 0 |
| RPLP0_ENST00000228306 | RPLP0 | P05388 | 60S acidic ribosomal protein P0 | chr12 | Not Cancer Driver | No | 1 | hippie | 44 | 36 | 4 | 4 | 0 |
| RPS10_ENST00000467531 | RPS10 | P46783 | 40S ribosomal protein S10 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 100 | 19 | 19 | 0 |
| RPS11 | RPS11 | P62280 | 40S ribosomal protein S11 | chr19 | Not Cancer Driver | No | 1 | hippie | 18 | 6 | 0 | 0 | 0 |
| RPS14_ENST00000521466 | RPS14 | P62263 | 40S ribosomal protein S14 | chr5 | Not Cancer Driver | No | 1 | hippie | 14 | 96 | 13 | 13 | 0 |
| RPS15A_ENST00000565420 | RPS15A | P62244 | 40S ribosomal protein S15a | chr16 | Not Cancer Driver | No | 1 | hippie | 6 | 4 | 0 | 0 | 0 |
| RPS16 | RPS16 | P62249 | 40S ribosomal protein S16 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 16 | 14 | 1 | 1 | 0 |
| RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 61 | 3 | 3 | 23 |
| RPS2 | RPS2 | P15880 | 40S ribosomal protein S2 | chr16 | Not Cancer Driver | No | 1 | hippie | 34 | 85 | 14 | 14 | 0 |
| RPS27 | RPS27 | P42677 | 40S ribosomal protein S27 | chr1 | Not Cancer Driver | No | 1 | hippie | 10 | 29 | 7 | 7 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | Not Cancer Driver | No | 1 | hippie | 4 | 22 | 2 | 2 | 0 |
| RPS3A | RPS3A | P61247 | 40S ribosomal protein S3a | chr4 | Compendium | Yes | 1 | hippie | 21 | 85 | 5 | 5 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 48 | 4 | 4 | 0 |
| RPS5_ENST00000601521 | RPS5 | P46782 | 40S ribosomal protein S5 | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 40 | 8 | 8 | 0 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | Not Cancer Driver | No | 1 | hippie | 38 | 150 | 25 | 25 | 0 |
| RPS9_ENST00000391752 | RPS9 | P46781 | 40S ribosomal protein S9 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 23 | 34 | 5 | 5 | 0 |
| RPSA_ENST00000301821 | RPSA | P08865 | 40S ribosomal protein SA | chr3 | Not Cancer Driver | No | 1 | hippie | 22 | 95 | 6 | 6 | 5 |
| RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | Not Cancer Driver | No | 1 | hippie | 176 | 241 | 21 | 21 | 0 |
| RWDD3 | RWDD3 | Q9Y3V2 | RWD domain-containing protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 12 | 4 | 4 | 0 |
| S100A11 | S100A11 | P31949 | Protein S100-A11 | chr1 | Not Cancer Driver | No | 1 | hippie | 13 | 14 | 2 | 2 | 0 |
| S100A8 | S100A8 | P05109 | Protein S100-A8 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 8 | 4 | 4 | 0 |
| S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 76 | 7 | 7 | 0 |
| SAP130_ENST00000259235 | SAP130 | Q9H0E3 | Histone deacetylase complex subunit SAP130 | chr2 | Not Cancer Driver | No | 1 | hippie | 119 | 940 | 107 | 107 | 0 |
| SAR1A_ENST00000373238 | SAR1A | Q9NR31 | GTP-binding protein SAR1a | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 4 | 0 | 0 | 0 |
| SARNP | SARNP | P82979 | SAP domain-containing ribonucleoprotein | chr12 | Not Cancer Driver | No | 1 | hippie | 27 | 195 | 27 | 27 | 0 |
| SAT2 | SAT2 | Q96F10 | Thialysine N-epsilon-acetyltransferase | chr17 | Not Cancer Driver | No | 1 | hippie | 14 | 0 | 0 | 0 | 0 |
| SEPT2_ENST00000360051 | SEPTIN2 | Q15019 | Septin-2 | chr2 | Not Cancer Driver | No | 1 | intact | 49 | 101 | 11 | 11 | 0 |
| SET | SET | Q01105 | Protein SET | chr9 | Census, Compendium | Yes | 1 | hippie | 35 | 221 | 26 | 26 | 2 |
| SETDB1 | SETDB1 | Q15047 | Histone-lysine N-methyltransferase SETDB1 | chr1 | Census, Compendium | Yes | 2 | hippie, biogrid | 184 | 597 | 77 | 77 | 0 |
| SF3A1 | SF3A1 | Q15459 | Splicing factor 3A subunit 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 82 | 631 | 67 | 67 | 0 |
| SF3B3 | SF3B3 | Q15393 | Splicing factor 3B subunit 3 | chr16 | Not Cancer Driver | No | 1 | hippie | 154 | 145 | 19 | 19 | 0 |
| SF3B6 | SF3B6 | Q9Y3B4 | Splicing factor 3B subunit 6 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 9 | 10 | 0 | 0 | 0 |
| SFTPA2 | SFTPA2 | Q8IWL1 | Pulmonary surfactant-associated protein A2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 174 | 43 | 43 | 7 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 70 | 435 | 31 | 31 | 0 |
| SKP2 | SKP2 | Q13309 | S-phase kinase-associated protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 52 | 52 | 6 | 6 | 0 |
| SLC2A1 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 13 | 2 | 2 | 48 |
| SLC3A2_ENST00000377890 | SLC3A2 | P08195 | 4F2 cell-surface antigen heavy chain | chr11 | Not Cancer Driver | No | 1 | hippie | 62 | 171 | 12 | 12 | 0 |
| SLFN12_ENST00000452764 | SLFN12 | Q8IYM2 | Ribonuclease SLFN12 | chr17 | Not Cancer Driver | No | 1 | hippie | 78 | 7 | 1 | 1 | 0 |
| SMARCC1 | SMARCC1 | Q92922 | SWI/SNF complex subunit SMARCC1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 125 | 720 | 81 | 81 | 0 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | Not Cancer Driver | No | 1 | hippie | 89 | 256 | 31 | 31 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 107 | 13 | 13 | 5 |
| SNRNP200 | SNRNP200 | O75643 | U5 small nuclear ribonucleoprotein 200 kDa helicase | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 237 | 270 | 37 | 37 | 11 |
| SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 416 | 37 | 37 | 0 |
| SNRPA1 | SNRPA1 | P09661 | U2 small nuclear ribonucleoprotein A' | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 93 | 14 | 14 | 0 |
| SNX3 | SNX3 | O60493 | Sorting nexin-3 | chr6 | Not Cancer Driver | No | 1 | hippie | 21 | 37 | 4 | 4 | 0 |
| SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | Census, Compendium | Yes | 1 | hippie | 22 | 66 | 3 | 3 | 2 |
| SOCS2_ENST00000536696 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 61 | 2 | 2 | 0 |
| SOCS3 | SOCS3 | O14543 | Suppressor of cytokine signaling 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 27 | 111 | 14 | 14 | 0 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 32 | 25 | 5 | 5 | 0 |
| SON | SON | P18583 | Protein SON | chr21 | Not Cancer Driver | No | 1 | hippie | 234 | 2109 | 212 | 212 | 0 |
| SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 599 | 71 | 71 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 71 | 194 | 35 | 35 | 2 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 46 | 169 | 29 | 29 | 1 |
| SPSB4 | SPSB4 | Q96A44 | SPRY domain-containing SOCS box protein 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 42 | 75 | 3 | 3 | 0 |
| SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 267 | 32 | 32 | 30 |
| SRP14 | SRP14 | P37108 | Signal recognition particle 14 kDa protein | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 10 | 74 | 8 | 8 | 0 |
| SRPRB | SRPRB | Q9Y5M8 | Signal recognition particle receptor subunit beta | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 23 | 3 | 3 | 0 |
| SSB | SSB | P05455 | Lupus La protein | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 181 | 18 | 18 | 0 |
| SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie | 26 | 114 | 10 | 10 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | Census, Compendium | Yes | 1 | hippie | 110 | 152 | 15 | 15 | 19 |
| STK16_ENST00000396738 | STK16 | O75716 | Serine/threonine-protein kinase 16 | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 42 | 48 | 3 | 3 | 0 |
| STK38 | STK38 | Q15208 | Serine/threonine-protein kinase 38 | chr6 | Not Cancer Driver | No | 1 | hippie | 57 | 77 | 6 | 6 | 0 |
| STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | Not Cancer Driver | No | 1 | hippie | 15 | 149 | 15 | 15 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | Not Cancer Driver | No | 1 | hippie | 35 | 112 | 14 | 14 | 12 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
| SUPT16H | SUPT16H | Q9Y5B9 | FACT complex subunit SPT16 | chr14 | Not Cancer Driver | No | 1 | hippie | 147 | 301 | 44 | 44 | 0 |
| TAGLN2_ENST00000368097 | TAGLN2 | P37802 | Transgelin-2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 28 | 83 | 12 | 12 | 0 |
| TARDBP | TARDBP | Q13148 | TAR DNA-binding protein 43 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 202 | 15 | 15 | 27 |
| TARS_ENST00000265112 | TARS1 | P26639 | Threonine--tRNA ligase 1, cytoplasmic | chr5 | Not Cancer Driver | No | 1 | intact | 112 | 112 | 22 | 22 | 2 |
| TBCA_ENST00000380377 | TBCA | O75347 | Tubulin-specific chaperone A | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 30 | 1 | 1 | 0 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | Not Cancer Driver | No | 1 | hippie | 101 | 42 | 5 | 5 | 12 |
| TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 54 | 55 | 10 | 10 | 0 |
| TET2 | TET2 | Q6N021 | Methylcytosine dioxygenase TET2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 1663 | 176 | 176 | 1 |
| TET3 | TET3 | O43151 | Methylcytosine dioxygenase TET3 | chr2 | Not Cancer Driver | No | 1 | hippie | 208 | 1272 | 152 | 152 | 6 |
| TGFB1I1 | TGFB1I1 | O43294 | Transforming growth factor beta-1-induced transcript 1 protein | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 61 | 219 | 34 | 34 | 0 |
| TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 86 | 23 | 3 | 3 | 15 |
| TGM2 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 107 | 26 | 26 | 0 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 399 | 46 | 46 | 0 |
| THOC1 | THOC1 | Q96FV9 | THO complex subunit 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 55 | 280 | 26 | 26 | 0 |
| TIMM17A | TIMM17A | Q99595 | Mitochondrial import inner membrane translocase subunit Tim17-A | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 22 | 2 | 2 | 0 |
| TKT_ENST00000462138 | TKT | P29401 | Transketolase | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 86 | 7 | 7 | 1 |
| TLE1 | TLE1 | Q04724 | Transducin-like enhancer protein 1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 111 | 381 | 53 | 53 | 0 |
| TMCO1 | TMCO1 | Q9UM00 | Calcium load-activated calcium channel | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 49 | 5 | 5 | 0 |
| TMED10 | TMED10 | P49755 | Transmembrane emp24 domain-containing protein 10 | chr14 | Not Cancer Driver | No | 1 | hippie | 24 | 15 | 3 | 3 | 0 |
| TMED2 | TMED2 | Q15363 | Transmembrane emp24 domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 25 | 4 | 4 | 0 |
| TMEM185A | TMEM185A | Q8NFB2 | Transmembrane protein 185A | chrX | Not Cancer Driver | No | 1 | hippie | 29 | 19 | 0 | 0 | 0 |
| TOP2A | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | Compendium | Yes | 1 | hippie | 150 | 508 | 59 | 59 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 17 | 43 | 6 | 6 | 0 |
| TRAFD1_ENST00000412615 | TRAFD1 | O14545 | TRAF-type zinc finger domain-containing protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 55 | 374 | 32 | 32 | 0 |
| TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
| TRIP12_ENST00000283943 | TRIP12 | Q14669 | E3 ubiquitin-protein ligase TRIP12 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 224 | 845 | 117 | 117 | 4 |
| TRMT112 | TRMT112 | Q9UI30 | Multifunctional methyltransferase subunit TRM112-like protein | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 17 | 2 | 2 | 0 |
| TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
| TUBA3D | TUBA3D | P0DPH8 | Tubulin alpha-3D chain | chr2 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 4 | 4 | 0 |
| TUBA3E | TUBA3E | Q6PEY2 | Tubulin alpha-3E chain | chr2 | Not Cancer Driver | No | 1 | hippie | 92 | 35 | 9 | 9 | 0 |
| TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | hippie | 73 | 39 | 4 | 4 | 5 |
| TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | Not Cancer Driver | No | 1 | hippie | 52 | 65 | 11 | 11 | 2 |
| TXN | TXN | P10599 | Thioredoxin | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 0 | 0 | 0 | 0 |
| TXNDC17 | TXNDC17 | Q9BRA2 | Thioredoxin domain-containing protein 17 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 0 | 0 | 0 | 0 |
| TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 61 | 77 | 14 | 14 | 0 |
| UBE2D1 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | Not Cancer Driver | No | 1 | hippie | 13 | 14 | 0 | 0 | 0 |
| UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | Compendium | Yes | 1 | hippie | 19 | 13 | 1 | 1 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 4 | 4 | 0 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
| UBE2K | UBE2K | P61086 | Ubiquitin-conjugating enzyme E2 K | chr4 | Not Cancer Driver | No | 1 | hippie | 24 | 33 | 3 | 3 | 0 |
| UBE2L3_ENST00000342192 | UBE2L3 | P68036 | Ubiquitin-conjugating enzyme E2 L3 | chr22 | Not Cancer Driver | No | 1 | hippie | 19 | 32 | 4 | 4 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 32 | 6 | 6 | 0 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 24 | 3 | 3 | 0 |
| UBE2O | UBE2O | Q9C0C9 | (E3-independent) E2 ubiquitin-conjugating enzyme | chr17 | Not Cancer Driver | No | 1 | hippie | 129 | 716 | 68 | 68 | 0 |
| UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | Not Cancer Driver | No | 1 | hippie | 25 | 102 | 12 | 12 | 0 |
| UBE2U_ENST00000611228 | UBE2U | Q5VVX9 | Ubiquitin-conjugating enzyme E2 U | chr1 | Not Cancer Driver | No | 1 | hippie | 38 | 66 | 1 | 1 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | Census, Compendium | Yes | 1 | hippie | 340 | 1296 | 162 | 162 | 0 |
| UBXN7 | UBXN7 | O94888 | UBX domain-containing protein 7 | chr3 | Not Cancer Driver | No | 1 | hippie | 65 | 327 | 39 | 39 | 0 |
| UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 34 | 7 | 7 | 4 |
| UFC1 | UFC1 | Q9Y3C8 | Ubiquitin-fold modifier-conjugating enzyme 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 10 | 0 | 0 | 2 |
| UQCC2 | UQCC2 | Q9BRT2 | Ubiquinol-cytochrome-c reductase complex assembly factor 2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 10 | 41 | 1 | 1 | 0 |
| UQCRFS1 | UQCRFS1 | P47985 | Cytochrome b-c1 complex subunit Rieske, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 43 | 47 | 4 | 4 | 1 |
| USP20_ENST00000358355 | USP20 | Q9Y2K6 | Ubiquitin carboxyl-terminal hydrolase 20 | chr9 | Not Cancer Driver | No | 1 | hippie | 112 | 295 | 36 | 36 | 0 |
| USP33_ENST00000357428 | USP33 | Q8TEY7 | Ubiquitin carboxyl-terminal hydrolase 33 | chr1 | Not Cancer Driver | No | 1 | hippie | 138 | 256 | 48 | 48 | 0 |
| USP39 | USP39 | Q53GS9 | U4/U6.U5 tri-snRNP-associated protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 58 | 128 | 10 | 10 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | Census, Compendium | Yes | 1 | hippie | 339 | 405 | 51 | 51 | 1 |
| UTRN | UTRN | P46939 | Utrophin | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 476 | 1283 | 183 | 183 | 0 |
| UXT_ENST00000333119 | UXT | Q9UBK9 | Protein UXT | chrX | Not Cancer Driver | No | 1 | hippie | 21 | 17 | 1 | 1 | 0 |
| VAMP3 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 11 | 17 | 1 | 1 | 0 |
| VAPB | VAPB | O95292 | Vesicle-associated membrane protein-associated protein B/C | chr20 | Not Cancer Driver | No | 1 | hippie | 16 | 138 | 8 | 8 | 3 |
| VARS | VARS1 | P26640 | Valine--tRNA ligase | chr6 | Not Cancer Driver | No | 1 | intact | 145 | 251 | 26 | 26 | 0 |
| VBP1 | VBP1 | P61758 | Prefoldin subunit 3 | chrX | Not Cancer Driver | No | 1 | hippie | 27 | 47 | 7 | 7 | 0 |
| VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | hippie | 142 | 117 | 36 | 36 | 133 |
| VKORC1L1_ENST00000360768 | VKORC1L1 | Q8N0U8 | Vitamin K epoxide reductase complex subunit 1-like protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 0 |
| VMA21 | VMA21 | Q3ZAQ7 | Vacuolar ATPase assembly integral membrane protein VMA21 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 18 | 7 | 1 | 1 | 0 |
| VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | Not Cancer Driver | No | 1 | hippie | 68 | 99 | 9 | 9 | 1 |
| WDR12 | WDR12 | Q9GZL7 | Ribosome biogenesis protein WDR12 | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 36 | 1 | 1 | 0 |
| WDR61 | WDR61 | Q9GZS3 | WD repeat-containing protein 61 | chr15 | Not Cancer Driver | No | 1 | hippie | 25 | 7 | 1 | 1 | 0 |
| WDTC1 | WDTC1 | Q8N5D0 | WD and tetratricopeptide repeats protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 81 | 154 | 21 | 21 | 0 |
| WSB1 | WSB1 | Q9Y6I7 | WD repeat and SOCS box-containing protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 25 | 3 | 3 | 0 |
| WTIP | WTIP | A6NIX2 | Wilms tumor protein 1-interacting protein | chr19 | Not Cancer Driver | No | 1 | hippie | 32 | 217 | 2 | 2 | 0 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 87 | 118 | 11 | 11 | 0 |
| YY1AP1_ENST00000295566 | YY1AP1 | Q9H869 | YY1-associated protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 117 | 484 | 74 | 74 | 0 |
| ZBTB44_ENST00000357899 | ZBTB44 | Q8NCP5 | Zinc finger and BTB domain-containing protein 44 | chr11 | Not Cancer Driver | No | 1 | hippie | 68 | 266 | 35 | 35 | 0 |
| ZBTB49 | ZBTB49 | Q6ZSB9 | Zinc finger and BTB domain-containing protein 49 | chr4 | Not Cancer Driver | No | 1 | hippie | 90 | 397 | 56 | 56 | 0 |
| ZBTB6 | ZBTB6 | Q15916 | Zinc finger and BTB domain-containing protein 6 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 120 | 15 | 15 | 0 |
| ZHX2 | ZHX2 | Q9Y6X8 | Zinc fingers and homeoboxes protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 151 | 593 | 103 | 103 | 0 |
| ZNF131 | ZNF131 | P52739 | Zinc finger protein 131 | chr5 | Not Cancer Driver | No | 1 | hippie | 79 | 266 | 41 | 41 | 0 |
| ZNF197_ENST00000344387 | ZNF197 | O14709 | Zinc finger protein 197 | chr3 | Not Cancer Driver | No | 1 | hippie | 119 | 227 | 28 | 28 | 0 |
| ZNF350 | ZNF350 | Q9GZX5 | Zinc finger protein 350 | chr19 | Not Cancer Driver | No | 1 | hippie | 86 | 95 | 18 | 18 | 0 |
| ZNF512B | ZNF512B | Q96KM6 | Zinc finger protein 512B | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 694 | 83 | 83 | 0 |
| ZYX | ZYX | Q15942 | Zyxin | chr7 | Not Cancer Driver | No | 1 | hippie | 83 | 385 | 52 | 52 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|