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HDAC1 ,HDAC1 ,Q13547
  • Uniprot Accession= Q13547
  • Ensembl Transcript= ENST00000373548.7
  • Uniprot Name= HDAC1
  • Name= Histone deacetylase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 246
  • Number of Interaction partner in biogrid: 163
  • Number of Interaction partner in hippie: 734
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 61 41 5 5 19
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 Census, Compendium Yes 1 hippie 78 0 0 0 1
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTR8 ACTR8 Q9H981 Actin-related protein 8 chr3 Not Cancer Driver No 1 biogrid 61 239 21 21 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 Not Cancer Driver No 1 hippie 106 439 64 64 0
ADH5 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 Not Cancer Driver No 1 hippie, biogrid 36 2 1 1 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 Not Cancer Driver No 2 intact, hippie, biogrid 130 615 66 66 0
AFF1_ENST00000307808 AFF1 P51825 AF4/FMR2 family member 1 chr4 Census, Compendium Yes 1 intact, hippie 150 1023 126 126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact, hippie 126 141 15 15 11
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 88 166 22 22 11
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 78 22 22 0
AIRE AIRE O43918 Autoimmune regulator chr21 Not Cancer Driver No 1 hippie 71 338 48 48 19
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 Not Cancer Driver No 1 intact, hippie 76 510 61 61 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 Census Yes 1 hippie 474 2281 268 268 1
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie, biogrid 21 30 1 1 0
ALDH1B1 ALDH1B1 P30837 Aldehyde dehydrogenase X, mitochondrial chr9 Not Cancer Driver No 1 intact, hippie 94 54 11 11 0
ANKRD13B ANKRD13B Q86YJ7 Ankyrin repeat domain-containing protein 13B chr17 Not Cancer Driver No 1 intact, hippie 64 290 18 18 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 67 292 31 31 1
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 Census, Compendium Yes 1 hippie 255 409 58 58 0
ARID4A ARID4A P29374 AT-rich interactive domain-containing protein 4A chr14 Not Cancer Driver No 5 intact, hippie, biogrid 151 978 123 123 0
ARID4B ARID4B Q4LE39 AT-rich interactive domain-containing protein 4B chr1 Not Cancer Driver No 5 intact, hippie, biogrid 143 1005 118 118 0
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 Not Cancer Driver No 4 intact, hippie, biogrid 162 769 95 95 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 Not Cancer Driver No 1 intact, hippie 26 0 0 0 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 77 511 56 56 0
ASCC2 ASCC2 Q9H1I8 Activating signal cointegrator 1 complex subunit 2 chr22 Not Cancer Driver No 1 hippie 87 326 34 34 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 Not Cancer Driver No 1 hippie 23 118 14 14 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 hippie 338 106 14 14 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX Census, Compendium Yes 1 hippie 487 1672 301 301 33
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 Not Cancer Driver No 1 hippie 105 328 39 39 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 17 112 9 9 0
BAHCC1 BAHCC1 Q9P281 BAH and coiled-coil domain-containing protein 1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 180 2253 142 142 0
BAHD1 BAHD1 Q8TBE0 Bromo adjacent homology domain-containing 1 protein chr15 Not Cancer Driver No 3 intact, hippie, biogrid 103 618 93 93 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 Not Cancer Driver No 1 hippie 10 11 2 2 1
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie 74 311 43 43 0
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 Not Cancer Driver No 2 intact, hippie 186 1283 118 118 0
BBX BBX Q8WY36 HMG box transcription factor BBX chr3 Not Cancer Driver No 1 intact, hippie, biogrid 147 842 125 125 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 Not Cancer Driver No 1 hippie 134 417 67 67 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 Census, Compendium Yes 4 hippie, biogrid 210 677 171 171 3
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 Census, Compendium Yes 3 intact, hippie, biogrid 156 699 114 114 2
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 Census Yes 1 hippie 44 259 23 23 0
BCL6B BCL6B Q8N143 B-cell CLL/lymphoma 6 member B protein chr17 Not Cancer Driver No 1 hippie 79 185 28 28 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 Census, Compendium Yes 1 hippie 134 328 67 67 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX Census, Compendium Yes 1 hippie 291 1285 226 226 1
BEND3_ENST00000369042 BEND3 Q5T5X7 BEN domain-containing protein 3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 104 311 44 44 0
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 Not Cancer Driver No 2 intact, hippie 52 242 31 31 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 Not Cancer Driver No 1 hippie 21 213 10 10 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX Not Cancer Driver No 1 hippie 106 172 27 27 0
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 Not Cancer Driver No 1 hippie, biogrid 309 2187 218 218 2
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX Not Cancer Driver No 1 hippie 39 74 7 7 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 Not Cancer Driver No 1 hippie 273 36 17 17 0
BRMS1L BRMS1L Q5PSV4 Breast cancer metastasis-suppressor 1-like protein chr14 Not Cancer Driver No 4 hippie, biogrid 35 160 17 17 0
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 Not Cancer Driver No 7 intact, hippie, biogrid 42 115 18 18 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 Not Cancer Driver No 1 hippie 139 466 64 64 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie 96 480 35 35 7
BUB3 BUB3 O43684 Mitotic checkpoint protein BUB3 chr10 Not Cancer Driver No 1 hippie 46 60 6 6 0
C16orf87 C16orf87 Q6PH81 UPF0547 protein C16orf87 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 17 103 8 8 0
C22orf31 C22orf31 O95567 Uncharacterized protein C22orf31 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 27 186 23 23 0
C2orf69 C2orf69 Q8N8R5 Mitochondrial protein C2orf69 chr2 Not Cancer Driver No 1 intact, hippie 32 80 1 1 0
CABIN1 CABIN1 Q9Y6J0 Calcineurin-binding protein cabin-1 chr22 Not Cancer Driver No 1 hippie 225 1008 95 95 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 intact, hippie 287 368 52 52 1
CARNMT1 CARNMT1 Q8N4J0 Carnosine N-methyltransferase chr9 Not Cancer Driver No 1 intact, hippie 42 75 1 1 0
CASP8AP2 CASP8AP2 Q9UKL3 CASP8-associated protein 2 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 219 1501 178 178 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 Census, Compendium Yes 1 hippie 83 502 70 70 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 hippie 21 116 12 12 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 Not Cancer Driver No 1 hippie 102 528 62 62 0
CCDC6 CCDC6 Q16204 Coiled-coil domain-containing protein 6 chr10 Census, Compendium Yes 1 hippie 59 373 52 52 0
CCDC71 CCDC71 Q8IV32 Coiled-coil domain-containing protein 71 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 61 374 47 47 0
CCN5_ENST00000190983 CCN5 O76076 CCN family member 5 chr20 Not Cancer Driver No 1 hippie 43 22 4 4 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 Not Cancer Driver No 1 hippie 49 145 14 14 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 hippie 55 31 25 25 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCNL2 CCNL2 Q96S94 Cyclin-L2 chr1 Not Cancer Driver No 1 hippie 77 251 33 33 0
CCSAP CCSAP Q6IQ19 Centriole, cilia and spindle-associated protein chr1 Not Cancer Driver No 1 intact, hippie 22 241 19 19 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 5 intact, hippie, biogrid 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 4 intact, hippie, biogrid 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 4 intact, hippie, biogrid 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 4 intact, hippie, biogrid 83 72 10 10 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 2 intact, hippie 66 5 1 1 0
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 90 1 0 0 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 4 intact, hippie, biogrid 59 36 6 6 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 3 intact, hippie 41 36 2 2 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 44 198 15 15 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 1 intact, hippie 215 717 80 80 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 2 intact, hippie 36 32 1 1 0
CDK2AP1 CDK2AP1 O14519 Cyclin-dependent kinase 2-associated protein 1 chr12 Not Cancer Driver No 6 intact, hippie, biogrid 10 76 8 8 0
CDK2AP2 CDK2AP2 O75956 Cyclin-dependent kinase 2-associated protein 2 chr11 Not Cancer Driver No 1 intact, hippie 10 126 10 10 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 Not Cancer Driver No 1 hippie 35 103 16 16 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 Not Cancer Driver No 1 intact, hippie 217 1136 128 128 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 2 intact, hippie 48 121 30 30 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 hippie 166 83 88 88 36
CDYL_ENST00000328908 CDYL Q9Y232 Chromodomain Y-like protein chr6 Not Cancer Driver No 4 hippie, biogrid 99 346 61 61 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 hippie 12 342 12 12 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 Not Cancer Driver No 1 hippie 3 276 2 2 0
CEBPD CEBPD P49716 CCAAT/enhancer-binding protein delta chr8 Not Cancer Driver No 1 hippie 5 234 4 4 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie, biogrid 15 50 4 4 0
CENPX_ENST00000392359 CENPX A8MT69 Centromere protein X chr17 Not Cancer Driver No 1 hippie 4 0 0 0 0
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie 127 690 72 72 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CEP44_ENST00000296519 CEP44 Q9C0F1 Centrosomal protein of 44 kDa chr4 Not Cancer Driver No 1 hippie 55 142 17 17 0
CHD1 CHD1 O14646 Chromodomain-helicase-DNA-binding protein 1 chr5 Not Cancer Driver No 1 hippie 172 975 109 109 4
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 5 intact, hippie, biogrid 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 13 intact, hippie, biogrid 419 974 177 177 6
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 365 931 183 183 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 Not Cancer Driver No 1 hippie 85 341 54 54 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIITA_ENST00000324288 CIITA P33076 MHC class II transactivator chr16 Census, Compendium Yes 1 hippie 195 318 53 53 2
CIR1 CIR1 Q86X95 Corepressor interacting with RBPJ 1 chr2 Not Cancer Driver No 1 hippie 46 385 42 42 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CNN3 CNN3 Q15417 Calponin-3 chr1 Not Cancer Driver No 1 intact, hippie 30 173 17 17 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 Not Cancer Driver No 1 hippie 155 370 61 61 0
COG4 COG4 Q9H9E3 Conserved oligomeric Golgi complex subunit 4 chr16 Not Cancer Driver No 1 intact, hippie 92 55 10 10 2
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie 25 277 23 23 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CREM_ENST00000429130 CREM Q03060 cAMP-responsive element modulator chr10 Not Cancer Driver No 1 intact, hippie 32 289 26 26 0
CROCC CROCC Q5TZA2 Rootletin chr1 Not Cancer Driver No 1 intact, hippie 254 1583 184 184 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 Not Cancer Driver No 1 hippie 22 59 11 11 4
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie 50 13 2 2 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 4 intact, hippie, biogrid 71 75 8 8 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 2 intact, hippie, biogrid 43 13 1 1 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie, biogrid 20 19 0 0 4
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 4 intact, hippie, biogrid 42 123 9 9 1
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 2 hippie, biogrid 48 94 4 4 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 Not Cancer Driver No 1 hippie 59 14 1 1 12
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie 41 7 2 2 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 64 102 2 2 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CYBRD1 CYBRD1 Q53TN4 Plasma membrane ascorbate-dependent reductase CYBRD1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 34 59 10 10 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 Not Cancer Driver No 1 hippie 157 641 134 134 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 Not Cancer Driver No 1 hippie 163 598 127 127 1
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 intact, hippie 106 549 81 81 0
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 Not Cancer Driver No 1 hippie 128 495 44 44 0
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 Census, Compendium Yes 1 hippie 45 70 5 5 2
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 Census Yes 1 hippie 29 160 27 27 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 2 intact, hippie 82 91 15 15 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 Not Cancer Driver No 1 hippie 91 362 48 48 0
DDX3Y_ENST00000336079 DDX3Y O15523 ATP-dependent RNA helicase DDX3Y chrY Not Cancer Driver No 1 hippie 31 289 18 18 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 Not Cancer Driver No 1 intact, hippie 19 15 1 1 0
DESI1 DESI1 Q6ICB0 Desumoylating isopeptidase 1 chr22 Not Cancer Driver No 1 intact, hippie 23 34 6 6 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie 165 260 40 40 6
DMAC1 DMAC1 Q96GE9 Distal membrane-arm assembly complex protein 1 chr9 Not Cancer Driver No 1 hippie 16 33 4 4 0
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 Not Cancer Driver No 1 hippie 49 269 28 28 0
DMD DMD P11532 Dystrophin chrX Not Cancer Driver No 1 hippie 895 1399 329 329 14
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 intact, hippie 50 174 27 27 0
DNAJC6_ENST00000395325 DNAJC6 O75061 Putative tyrosine-protein phosphatase auxilin chr1 Not Cancer Driver No 1 hippie 165 455 82 82 1
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 203 702 78 78 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 Census, Compendium Yes 1 hippie 194 371 59 59 16
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 Not Cancer Driver No 1 hippie 153 328 71 71 16
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 Not Cancer Driver No 2 intact, hippie 83 10 1 1 0
DNTTIP1 DNTTIP1 Q9H147 Deoxynucleotidyltransferase terminal-interacting protein 1 chr20 Not Cancer Driver No 5 intact, hippie, biogrid 48 170 30 30 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 67 179 30 30 5
DZIP3_ENST00000463306 DZIP3 Q86Y13 E3 ubiquitin-protein ligase DZIP3 chr3 Not Cancer Driver No 1 hippie 177 370 68 68 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 1 hippie 49 272 23 23 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 1 hippie 46 253 20 20 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 Not Cancer Driver No 1 hippie 44 242 32 32 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 20 105 10 10 0
E4F1 E4F1 Q66K89 Transcription factor E4F1 chr16 Not Cancer Driver No 2 intact, hippie 84 462 46 46 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 3 intact, hippie 64 79 11 11 6
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 intact, hippie 74 121 17 17 3
EFCAB6 EFCAB6 Q5THR3 EF-hand calcium-binding domain-containing protein 6 chr22 Not Cancer Driver No 1 hippie 262 356 77 77 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 Not Cancer Driver No 3 hippie, biogrid 182 701 97 97 1
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 Not Cancer Driver No 5 intact, hippie, biogrid 142 585 71 71 0
EID2 EID2 Q8N6I1 EP300-interacting inhibitor of differentiation 2 chr19 Not Cancer Driver No 1 hippie 18 136 8 8 0
EID2B EID2B Q96D98 EP300-interacting inhibitor of differentiation 2B chr19 Not Cancer Driver No 1 hippie 9 90 2 2 0
EID3 EID3 Q8N140 EP300-interacting inhibitor of differentiation 3 chr12 Not Cancer Driver No 1 intact, hippie 40 55 6 6 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX Not Cancer Driver No 1 hippie 51 327 34 34 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 Census, Compendium Yes 1 hippie 67 446 53 53 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie 42 160 28 28 4
EMSY_ENST00000529032 EMSY Q7Z589 BRCA2-interacting transcriptional repressor EMSY chr11 Not Cancer Driver No 3 intact, hippie 166 1151 147 147 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 Not Cancer Driver No 1 hippie, biogrid 397 2064 234 234 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 1 hippie 120 449 53 53 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 intact, hippie 211 829 117 117 9
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 intact, hippie 95 296 54 54 0
ESCO1 ESCO1 Q5FWF5 N-acetyltransferase ESCO1 chr18 Not Cancer Driver No 1 hippie 92 594 66 66 0
ESCO2 ESCO2 Q56NI9 N-acetyltransferase ESCO2 chr8 Not Cancer Driver No 1 hippie 67 292 32 32 1
ESD ESD P10768 S-formylglutathione hydrolase chr13 Not Cancer Driver No 1 hippie, biogrid 33 4 0 0 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETHE1 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 Not Cancer Driver No 1 hippie 21 6 0 0 9
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 Not Cancer Driver No 1 hippie 41 8 1 1 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 2 hippie, biogrid 120 284 44 44 11
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 intact, hippie 176 181 14 14 3
FEZF2_ENST00000475839 FEZF2 Q8TBJ5 Fez family zinc finger protein 2 chr3 Not Cancer Driver No 1 hippie 65 144 14 14 0
FKBP3_ENST00000396062 FKBP3 Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 chr14 Not Cancer Driver No 1 hippie 27 131 17 17 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 intact, hippie 56 20 3 3 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FOLH1 FOLH1 Q04609 Glutamate carboxypeptidase 2 chr11 Not Cancer Driver No 1 hippie 200 43 13 13 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 Not Cancer Driver No 1 hippie 24 271 24 24 0
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 Not Cancer Driver No 1 hippie 132 322 79 79 2
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 Not Cancer Driver No 2 intact, hippie 25 279 18 18 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 97 511 65 65 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 hippie, biogrid 79 548 64 64 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX Not Cancer Driver No 1 hippie 38 186 16 16 10
FSCN1 FSCN1 Q16658 Fascin chr7 Not Cancer Driver No 1 hippie 58 81 5 5 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 1 intact, hippie 103 533 66 66 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 Not Cancer Driver No 1 hippie 58 103 8 8 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX Census, Compendium Yes 1 hippie 68 242 41 41 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 Census, Compendium Yes 1 hippie 72 370 49 49 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 Census, Compendium Yes 1 intact, hippie 111 364 87 87 2
GATAD1 GATAD1 Q8WUU5 GATA zinc finger domain-containing protein 1 chr7 Not Cancer Driver No 4 intact, hippie, biogrid 14 131 4 4 1
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 Not Cancer Driver No 6 hippie, biogrid 88 548 77 77 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 9 intact, hippie, biogrid 76 510 67 67 0
GCM1 GCM1 Q9NP62 Chorion-specific transcription factor GCMa chr6 Not Cancer Driver No 1 hippie 78 194 36 36 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 intact, hippie 327 117 16 16 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 Not Cancer Driver No 1 hippie 57 199 29 29 2
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 206 1015 184 184 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 Not Cancer Driver No 1 hippie 287 1403 244 244 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 Not Cancer Driver No 1 hippie 385 1352 327 327 7
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie 52 24 4 4 0
GMNN_ENST00000620958 GMNN O75496 Geminin chr6 Not Cancer Driver No 1 hippie 24 206 24 24 1
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 108 83 7 7 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 Not Cancer Driver No 1 intact, hippie 29 319 26 26 0
GRIP1_ENST00000359742 GRIP1 Q9Y3R0 Glutamate receptor-interacting protein 1 chr12 Not Cancer Driver No 1 hippie 203 568 101 101 0
GSE1 GSE1 Q14687 Genetic suppressor element 1 chr16 Not Cancer Driver No 5 intact, hippie, biogrid 115 1133 110 110 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 55 180 8 8 0
GTF2I GTF2I P78347 General transcription factor II-I chr7 Compendium Yes 1 hippie 74 365 27 27 0
HAUS2 HAUS2 Q9NVX0 HAUS augmin-like complex subunit 2 chr15 Not Cancer Driver No 1 hippie 31 8 0 0 0
HBP1_ENST00000468410 HBP1 O60381 HMG box-containing protein 1 chr7 Not Cancer Driver No 1 hippie 48 263 16 16 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX Not Cancer Driver No 1 intact, hippie 280 1345 181 181 1
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 16 intact, hippie, biogrid 46 145 14 14 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 2 intact, hippie 65 61 8 8 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 hippie 91 570 50 50 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie 286 631 178 178 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 intact, hippie 35 203 29 29 0
HECA HECA Q9UBI9 Headcase protein homolog chr6 Not Cancer Driver No 1 hippie 76 177 24 24 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 Not Cancer Driver No 1 hippie 78 227 25 25 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 Not Cancer Driver No 1 hippie 124 118 12 12 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 Not Cancer Driver No 1 hippie 37 226 32 32 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 Not Cancer Driver No 1 hippie 64 179 26 26 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 Not Cancer Driver No 1 hippie 24 361 6 6 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HIGD1A_ENST00000418900 HIGD1A Q9Y241 HIG1 domain family member 1A, mitochondrial chr3 Not Cancer Driver No 1 hippie 17 8 0 0 0
HIGD1C HIGD1C A8MV81 HIG1 domain family member 1C chr12 Not Cancer Driver No 1 intact, hippie 8 10 0 0 0
HINFP HINFP Q9BQA5 Histone H4 transcription factor chr11 Not Cancer Driver No 1 hippie 65 154 24 24 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 Not Cancer Driver No 1 intact, hippie 107 412 98 98 0
HMG20A HMG20A Q9NP66 High mobility group protein 20A chr15 Not Cancer Driver No 4 hippie, biogrid 58 308 44 44 0
HMG20B HMG20B Q9P0W2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related chr19 Not Cancer Driver No 5 intact, hippie, biogrid 27 237 18 18 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 intact, hippie 108 463 67 67 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie 67 304 25 25 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 Census, Compendium Yes 1 hippie 37 205 26 26 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 Census Yes 1 intact, hippie 46 187 35 35 0
HR HR O43593 Lysine-specific demethylase hairless chr8 Not Cancer Driver No 1 hippie 130 587 74 74 3
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 Not Cancer Driver No 1 hippie 27 30 0 0 14
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 27 15 3 3 11
HSDL2 HSDL2 Q6YN16 Hydroxysteroid dehydrogenase-like protein 2 chr9 Not Cancer Driver No 1 intact, hippie 37 41 5 5 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 Not Cancer Driver No 1 hippie 59 335 37 37 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 intact, hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie 61 82 6 6 2
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 hippie 25 17 2 2 0
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 intact, hippie, biogrid 74 59 1 1 7
IFRD1_ENST00000005558 IFRD1 O00458 Interferon-related developmental regulator 1 chr7 Not Cancer Driver No 1 hippie 60 87 10 10 0
IKZF1 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 2 hippie, biogrid 143 326 92 92 5
IKZF2 IKZF2 Q9UKS7 Zinc finger protein Helios chr2 Not Cancer Driver No 1 intact, hippie, biogrid 114 339 65 65 0
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
ING1 ING1 Q9UK53 Inhibitor of growth protein 1 chr13 Compendium Yes 3 intact, hippie, biogrid 69 209 33 33 3
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 Not Cancer Driver No 4 intact, hippie, biogrid 33 169 26 26 0
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 Not Cancer Driver No 1 hippie 25 359 12 12 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 Not Cancer Driver No 1 intact, hippie 128 52 3 3 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 Not Cancer Driver No 1 hippie 93 237 64 64 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 Not Cancer Driver No 1 hippie 16 142 13 13 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 112 241 37 37 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 hippie 65 173 21 21 3
KCTD11 KCTD11 Q693B1 BTB/POZ domain-containing protein KCTD11 chr17 Not Cancer Driver No 1 hippie 35 54 4 4 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 8 intact, hippie, biogrid 67 291 28 28 3
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 Not Cancer Driver No 1 hippie 122 337 44 44 0
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 Not Cancer Driver No 1 hippie 124 309 40 40 0
KDM5A KDM5A P29375 Lysine-specific demethylase 5A chr12 Census, Compendium Yes 4 intact, hippie, biogrid 220 503 66 66 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 Not Cancer Driver No 1 hippie 219 388 58 58 0
KDM5C KDM5C P41229 Lysine-specific demethylase 5C chrX Census, Compendium Yes 1 intact, hippie 167 499 46 46 10
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KLF1 KLF1 Q13351 Krueppel-like factor 1 chr19 Not Cancer Driver No 1 hippie 33 279 23 23 1
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 57 308 38 38 2
KLF4 KLF4 O43474-1 Isoform 2 of Krueppel-like factor 4 chr9 Census, Compendium Yes 1 hippie 58 415 38 38 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 Compendium Yes 1 hippie 77 366 40 40 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 hippie 446 3145 338 338 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 Not Cancer Driver No 1 hippie 233 1613 198 198 4
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 65 121 18 18 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 65 108 11 11 0
KPNA4 KPNA4 O00629 Importin subunit alpha-3 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 59 112 12 12 0
KPNA6 KPNA6 O60684 Importin subunit alpha-7 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 70 97 17 17 0
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie 65 221 37 37 3
L3MBTL2 L3MBTL2 Q969R5 Lethal(3)malignant brain tumor-like protein 2 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 95 210 38 38 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 intact, hippie, biogrid 178 687 116 116 0
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 Not Cancer Driver No 1 hippie 54 388 46 46 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 intact, hippie 40 9 0 0 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 Census Yes 1 hippie 64 370 57 57 0
LIN9 LIN9 Q5TKA1 Protein lin-9 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 67 219 25 25 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 Not Cancer Driver No 1 hippie 134 39 4 4 0
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 Not Cancer Driver No 1 hippie 41 188 20 20 0
LUC7L3_ENST00000240304 LUC7L3 O95232 Luc7-like protein 3 chr17 Not Cancer Driver No 1 hippie 59 323 47 47 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie 117 526 77 77 0
MAFK MAFK O60675 Transcription factor MafK chr7 Not Cancer Driver No 1 hippie 13 135 12 12 0
MAGEA1 MAGEA1 P43355 Melanoma-associated antigen 1 chrX Not Cancer Driver No 1 hippie 68 71 15 15 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX Not Cancer Driver No 1 hippie 79 103 18 18 0
MAGEA6 MAGEA6 P43360 Melanoma-associated antigen 6 chrX Not Cancer Driver No 1 hippie 95 103 20 20 0
MAGEB2 MAGEB2 O15479 Melanoma-associated antigen B2 chrX Not Cancer Driver No 1 hippie 98 126 35 35 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 Not Cancer Driver No 1 hippie 332 1947 278 278 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 Not Cancer Driver No 1 hippie 88 107 16 16 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 Not Cancer Driver No 1 hippie, biogrid 23 64 2 2 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie, biogrid 39 25 1 1 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 64 94 9 9 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 Not Cancer Driver No 1 hippie 59 90 8 8 0
MBD1_ENST00000591416 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 Not Cancer Driver No 1 hippie 115 322 49 49 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 9 intact, hippie, biogrid 26 384 25 25 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 Not Cancer Driver No 11 intact, hippie, biogrid 50 246 46 46 0
MBD3L1_ENST00000305625 MBD3L1 Q8WWY6 Methyl-CpG-binding domain protein 3-like 1 chr19 Not Cancer Driver No 4 intact, hippie, biogrid 41 68 18 18 0
MBD3L2 MBD3L2 Q8NHZ7 Methyl-CpG-binding domain protein 3-like 2 chr19 Not Cancer Driver No 2 hippie, biogrid 7 188 7 7 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 Not Cancer Driver No 1 hippie 61 268 27 27 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 Not Cancer Driver No 1 hippie 140 206 36 36 1
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 1 hippie 101 122 13 13 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 hippie 75 483 74 74 46
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 Not Cancer Driver No 1 hippie 62 454 56 56 0
MEF2D MEF2D Q14814 Myocyte-specific enhancer factor 2D chr1 Not Cancer Driver No 1 hippie 72 455 67 67 0
MEN1 MEN1 O00255 Menin chr11 Census, Compendium Yes 1 hippie 73 228 15 15 90
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 74 274 29 29 0
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 3 intact, hippie, biogrid 341 2317 259 259 0
MIER1_ENST00000355356 MIER1 Q8N108 Mesoderm induction early response protein 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 64 373 45 45 0
MIER2 MIER2 Q8N344 Mesoderm induction early response protein 2 chr19 Not Cancer Driver No 4 intact, hippie, biogrid 72 365 45 45 0
MIER3_ENST00000381199 MIER3 Q7Z3K6 Mesoderm induction early response protein 3 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 52 321 36 36 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie 540 3169 529 529 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MKX MKX Q8IYA7 Homeobox protein Mohawk chr10 Not Cancer Driver No 1 hippie 87 288 81 81 0
MNT MNT Q99583 Max-binding protein MNT chr17 Not Cancer Driver No 1 hippie 57 542 56 56 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 43 163 17 17 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX Not Cancer Driver No 1 intact, hippie 44 136 21 21 0
MPZL1 MPZL1 O95297 Myelin protein zero-like protein 1 chr1 Not Cancer Driver No 1 hippie 36 56 7 7 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 14 intact, hippie, biogrid 92 327 42 42 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 17 intact, hippie, biogrid 78 283 32 32 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 Not Cancer Driver No 9 intact, hippie, biogrid 48 169 18 18 0
MUC5B MUC5B Q9HC84 Mucin-5B chr11 Not Cancer Driver No 1 hippie 911 3134 586 586 0
MXD1 MXD1 Q05195 Max dimerization protein 1 chr2 Not Cancer Driver No 1 hippie 27 171 24 24 0
MXI1_ENST00000239007 MXI1 P50539 Max-interacting protein 1 chr10 Not Cancer Driver No 1 hippie 22 187 18 18 1
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 Census, Compendium Yes 1 intact, hippie 71 415 64 64 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH1 MYH1 P12882 Myosin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 546 1153 335 335 0
MYH2_ENST00000397183 MYH2 Q9UKX2 Myosin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 572 1073 338 338 1
MYH4 MYH4 Q9Y623 Myosin-4 chr17 Not Cancer Driver No 1 hippie, biogrid 464 1138 288 288 0
MYH7 MYH7 P12883 Myosin-7 chr14 Not Cancer Driver No 1 hippie, biogrid 464 1107 276 276 200
MYH8 MYH8 P13535 Myosin-8 chr17 Not Cancer Driver No 1 hippie, biogrid 498 1086 315 315 2
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie 126 61 6 6 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 Census Yes 1 hippie 45 246 33 33 0
MYT1 MYT1 Q01538 Myelin transcription factor 1 chr20 Not Cancer Driver No 1 hippie 226 969 189 189 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 Not Cancer Driver No 1 hippie 24 238 10 10 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie 352 2347 340 340 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 2 intact, hippie 373 2355 356 356 0
NELFB_ENST00000634710 NELFB Q8WX92-2 Isoform 2 of Negative elongation factor B chr9 Not Cancer Driver No 1 hippie 69 132 3 3 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 1 hippie 173 713 130 130 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 194 722 162 162 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 1 hippie 228 402 62 62 4
NFE4 NFE4 Q86UQ8 Transcription factor NF-E4 chr7 Not Cancer Driver No 1 hippie 15 136 11 11 0
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 hippie 60 305 40 40 6
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 3 intact, hippie 104 344 38 38 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 hippie 86 510 46 46 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 hippie 37 102 9 9 1
NFYA NFYA P23511 Nuclear transcription factor Y subunit alpha chr6 Not Cancer Driver No 1 hippie 43 187 29 29 0
NFYB NFYB P25208 Nuclear transcription factor Y subunit beta chr12 Not Cancer Driver No 1 hippie 23 94 7 7 0
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 1 hippie 46 320 32 32 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 Not Cancer Driver No 1 hippie 84 206 65 65 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 Not Cancer Driver No 1 hippie 48 181 22 22 55
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 Not Cancer Driver No 1 hippie 35 171 16 16 0
NKX3-2 NKX3-2 P78367 Homeobox protein Nkx-3.2 chr4 Not Cancer Driver No 1 hippie 36 212 27 27 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 Not Cancer Driver No 1 intact, hippie 74 662 69 69 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 hippie 116 510 72 72 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact, hippie 29 249 22 22 0
NR0B2 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 Not Cancer Driver No 1 intact, hippie 35 10 2 2 0
NR1D2 NR1D2 Q14995 Nuclear receptor subfamily 1 group D member 2 chr3 Not Cancer Driver No 1 hippie 76 223 25 25 0
NR2C1 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 Not Cancer Driver No 1 hippie 65 156 13 13 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 Not Cancer Driver No 1 hippie 75 57 6 6 0
NR2E3 NR2E3 Q9Y5X4 Photoreceptor-specific nuclear receptor chr15 Not Cancer Driver No 1 hippie 47 171 15 15 16
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 Not Cancer Driver No 1 hippie 66 101 1 1 5
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 Not Cancer Driver No 1 hippie 62 252 24 24 0
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 Not Cancer Driver No 1 hippie 60 133 29 29 24
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 Not Cancer Driver No 1 hippie 141 998 124 124 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie 21 37 3 3 0
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 intact, hippie 58 333 40 40 0
NUP54 NUP54 Q7Z3B4 Nucleoporin p54 chr4 Not Cancer Driver No 1 hippie 42 233 25 25 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OVOL1 OVOL1 O14753 Putative transcription factor Ovo-like 1 chr11 Not Cancer Driver No 1 hippie 31 69 9 9 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 Not Cancer Driver No 1 hippie 29 139 8 8 0
PAAF1 PAAF1 Q9BRP4 Proteasomal ATPase-associated factor 1 chr11 Not Cancer Driver No 1 hippie 47 23 3 3 0
PADI4 PADI4 Q9UM07 Protein-arginine deiminase type-4 chr1 Not Cancer Driver No 1 hippie 115 114 23 23 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 Not Cancer Driver No 1 hippie 97 293 28 28 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 intact, hippie 11 30 0 0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 119 320 34 34 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 Not Cancer Driver No 1 intact, hippie 74 172 23 23 0
PARP4 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 Compendium Yes 1 hippie 218 325 40 40 0
PAX3_ENST00000350526 PAX3 P23760 Paired box protein Pax-3 chr2 Census Yes 1 hippie 113 391 95 95 28
PBRM1_ENST00000296302 PBRM1 Q86U86 Protein polybromo-1 chr3 Census, Compendium Yes 1 hippie 209 703 77 77 0
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 Census Yes 1 hippie 82 290 57 57 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 3 hippie, biogrid 29 142 11 11 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PCNT PCNT O95613 Pericentrin chr21 Not Cancer Driver No 1 hippie 436 2474 337 337 0
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 Not Cancer Driver No 1 hippie 15 91 7 7 0
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 Not Cancer Driver No 1 hippie 48 73 13 13 0
PEX10_ENST00000447513 PEX10 O60683 Peroxisome biogenesis factor 10 chr1 Not Cancer Driver No 1 intact, hippie 23 17 0 0 1
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 hippie 38 266 28 28 0
PFDN1 PFDN1 O60925 Prefoldin subunit 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 8 42 4 4 0
PFDN2 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 2 hippie, biogrid 18 111 11 11 0
PFDN4 PFDN4 Q9NQP4 Prefoldin subunit 4 chr20 Not Cancer Driver No 1 intact, hippie 22 40 6 6 0
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 3 hippie, biogrid 18 3 0 0 0
PFDN6_ENST00000374610 PFDN6 O15212 Prefoldin subunit 6 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 14 57 8 8 0
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 30 74 16 16 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie 31 26 4 4 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 Not Cancer Driver No 1 hippie 62 277 29 29 0
PHF12 PHF12 Q96QT6 PHD finger protein 12 chr17 Not Cancer Driver No 4 hippie, biogrid 107 619 68 68 0
PHF14 PHF14 O94880 PHD finger protein 14 chr7 Not Cancer Driver No 1 intact, hippie 102 565 56 56 0
PHF20L1 PHF20L1 A8MW92 PHD finger protein 20-like protein 1 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 163 645 87 87 0
PHF21A PHF21A Q96BD5 PHD finger protein 21A chr11 Not Cancer Driver No 5 intact, hippie, biogrid 83 546 68 68 0
PHF21B PHF21B Q96EK2 PHD finger protein 21B chr22 Not Cancer Driver No 3 intact, hippie, biogrid 97 401 78 78 0
PHF6_ENST00000370803 PHF6 Q8IWS0 PHD finger protein 6 chrX Census, Compendium Yes 1 hippie 52 172 19 19 6
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 Not Cancer Driver No 1 intact, hippie 134 744 29 29 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 Not Cancer Driver No 1 hippie 70 266 31 31 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 58 142 23 23 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIMREG PIMREG Q9BSJ6 Protein PIMREG chr17 Not Cancer Driver No 1 hippie 38 233 36 36 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie, biogrid 17 115 12 12 0
PITX2_ENST00000354925 PITX2 Q99697 Pituitary homeobox 2 chr4 Not Cancer Driver No 1 hippie 74 185 43 43 13
PLAGL1_ENST00000367571 PLAGL1 Q9UM63 Zinc finger protein PLAGL1 chr6 Not Cancer Driver No 1 hippie 49 217 24 24 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 Not Cancer Driver No 1 hippie 102 451 45 45 0
PLRG1 PLRG1 O43660 Pleiotropic regulator 1 chr4 Not Cancer Driver No 1 intact, hippie 75 204 25 25 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 Not Cancer Driver No 1 hippie 51 326 39 39 0
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 hippie, biogrid 155 113 17 17 15
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 53 30 9 9 3
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 Not Cancer Driver No 1 hippie 95 433 50 50 0
PPA1 PPA1 Q15181 Inorganic pyrophosphatase chr10 Not Cancer Driver No 1 hippie 31 24 0 0 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie 72 69 7 7 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 179 0 0 0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 intact, hippie 72 17 1 1 0
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 Not Cancer Driver No 1 hippie 89 255 29 29 0
PPP6R3_ENST00000393800 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 Not Cancer Driver No 1 hippie 108 389 52 52 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 Census, Compendium Yes 1 hippie 145 337 66 66 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRDM4 PRDM4 Q9UKN5 PR domain zinc finger protein 4 chr12 Not Cancer Driver No 1 hippie 92 362 40 40 0
PRDM5 PRDM5 Q9NQX1 PR domain zinc finger protein 5 chr4 Not Cancer Driver No 1 intact, hippie 135 148 41 41 1
PRDM6 PRDM6 Q9NQX0 Putative histone-lysine N-methyltransferase PRDM6 chr5 Not Cancer Driver No 1 hippie 29 241 7 7 2
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 Not Cancer Driver No 1 hippie 37 149 13 13 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 Not Cancer Driver No 1 intact, hippie 60 125 4 4 0
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 Not Cancer Driver No 1 hippie 167 93 22 22 1
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 intact, hippie 71 109 16 16 0
PRRG4 PRRG4 Q9BZD6 Transmembrane gamma-carboxyglutamic acid protein 4 chr11 Not Cancer Driver No 1 intact, hippie 17 53 8 8 0
PTMA PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 10 111 10 10 0
PTOV1_ENST00000599732 PTOV1 Q86YD1 Prostate tumor-overexpressed gene 1 protein chr19 Not Cancer Driver No 1 hippie 56 122 8 8 0
PWWP2A PWWP2A Q96N64 PWWP domain-containing protein 2A chr5 Census Yes 4 intact, hippie, biogrid 57 601 46 46 0
PWWP2B PWWP2B Q6NUJ5 PWWP domain-containing protein 2B chr10 Not Cancer Driver No 2 intact, hippie, biogrid 60 451 51 51 0
RABEP2 RABEP2 Q9H5N1 Rab GTPase-binding effector protein 2 chr16 Not Cancer Driver No 1 hippie 87 441 71 71 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 Not Cancer Driver No 1 hippie 34 135 7 7 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 Not Cancer Driver No 1 hippie 65 381 46 46 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 Not Cancer Driver No 1 hippie 27 5 0 0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 1 hippie 70 167 14 14 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 2 hippie, biogrid 140 282 32 32 22
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 intact, hippie 202 578 75 75 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 8 intact, hippie, biogrid 53 169 23 23 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 12 intact, hippie, biogrid 67 138 19 19 0
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 Not Cancer Driver No 1 hippie 140 335 41 41 0
RBL2 RBL2 Q08999 Retinoblastoma-like protein 2 chr16 Not Cancer Driver No 1 hippie 116 504 56 56 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBP1_ENST00000619087 RBP1 P09455 Retinol-binding protein 1 chr3 Not Cancer Driver No 1 hippie 24 0 0 0 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 49 151 19 19 2
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 intact, hippie 35 125 11 11 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 Not Cancer Driver No 11 intact, hippie, biogrid 47 324 28 28 0
RCOR2 RCOR2 Q8IZ40 REST corepressor 2 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 57 369 35 35 0
RCOR3_ENST00000367005 RCOR3 Q9P2K3 REST corepressor 3 chr1 Not Cancer Driver No 5 intact, hippie, biogrid 70 332 45 45 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 hippie 68 363 43 43 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RELB RELB Q01201 Transcription factor RelB chr19 Not Cancer Driver No 1 hippie 65 348 39 39 0
REPIN1_ENST00000397281 REPIN1 Q9BWE0 Replication initiator 1 chr7 Not Cancer Driver No 1 hippie 62 259 28 28 0
RERE RERE Q9P2R6 Arginine-glutamic acid dipeptide repeats protein chr1 Not Cancer Driver No 4 hippie, biogrid 196 1297 167 167 0
REST REST Q13127 RE1-silencing transcription factor chr4 Not Cancer Driver No 1 hippie 142 868 113 113 4
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 Not Cancer Driver No 1 hippie 147 674 82 82 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie 58 50 8 8 0
RFX1 RFX1 P22670 MHC class II regulatory factor RFX1 chr19 Not Cancer Driver No 1 hippie 114 536 66 66 0
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 Not Cancer Driver No 1 hippie 113 308 41 41 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie 212 366 50 50 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 Not Cancer Driver No 2 hippie, biogrid 60 302 44 44 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 44 34 6 6 0
RNF157 RNF157 Q96PX1 E3 ubiquitin ligase RNF157 chr17 Not Cancer Driver No 1 hippie 76 375 39 39 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 Not Cancer Driver No 1 hippie 96 187 36 36 1
RPS27A_ENST00000404735 RPS27A P62979 Ubiquitin-40S ribosomal protein S27a chr2 Not Cancer Driver No 1 intact, hippie 18 47 2 2 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 Not Cancer Driver No 4 intact, hippie, biogrid 213 1152 144 144 0
RSPRY1_ENST00000394420 RSPRY1 Q96DX4 RING finger and SPRY domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 64 98 18 18 1
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 Not Cancer Driver No 1 hippie 57 74 7 7 0
RUNX1T1_ENST00000614812 RUNX1T1 Q06455 Protein CBFA2T1 chr8 Census, Compendium Yes 1 hippie 292 469 229 229 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 hippie 81 360 58 58 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 Not Cancer Driver No 1 hippie 83 447 73 73 47
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 Not Cancer Driver No 1 hippie 59 331 45 45 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 Not Cancer Driver No 1 hippie 54 67 7 7 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 hippie 62 100 13 13 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie, biogrid 37 214 37 37 0
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 Not Cancer Driver No 2 hippie, biogrid 454 949 334 334 0
SALL4 SALL4 Q9UJQ4 Sal-like protein 4 chr20 Census, Compendium Yes 1 hippie, biogrid 238 738 188 188 1
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 Not Cancer Driver No 1 hippie 112 291 85 85 0
SAP130_ENST00000259235 SAP130 Q9H0E3 Histone deacetylase complex subunit SAP130 chr2 Not Cancer Driver No 5 intact, hippie, biogrid 119 940 107 107 0
SAP18_ENST00000607003 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 Not Cancer Driver No 1 hippie 18 99 14 14 0
SAP30 SAP30 O75446 Histone deacetylase complex subunit SAP30 chr4 Not Cancer Driver No 4 hippie, biogrid 26 123 17 17 0
SAP30L SAP30L Q9HAJ7 Histone deacetylase complex subunit SAP30L chr5 Not Cancer Driver No 4 intact, hippie, biogrid 18 111 14 14 0
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 Compendium Yes 1 hippie 130 482 84 84 12
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 Not Cancer Driver No 1 hippie 164 412 100 100 0
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 Not Cancer Driver No 1 hippie 64 355 44 44 0
SERPINB5 SERPINB5 P36952 Serpin B5 chr18 Not Cancer Driver No 1 hippie 57 50 7 7 0
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 35 221 26 26 2
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 2 intact, hippie 184 597 77 77 0
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie 82 631 67 67 0
SFMBT1 SFMBT1 Q9UHJ3 Scm-like with four MBT domains protein 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 93 201 26 26 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 Census Yes 1 hippie 59 595 48 48 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 12 intact, hippie, biogrid 172 617 73 73 0
SIN3B SIN3B O75182 Paired amphipathic helix protein Sin3b chr19 Not Cancer Driver No 6 intact, hippie, biogrid 130 316 32 32 0
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 Not Cancer Driver No 3 intact, hippie 24 108 10 10 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 70 435 31 31 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SKI SKI P12755 Ski oncogene chr1 Census Yes 1 intact, hippie 44 432 26 26 14
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 Not Cancer Driver No 1 hippie 77 356 32 32 0
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 49 32 4 4 1
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLC39A7 SLC39A7 Q92504 Zinc transporter SLC39A7 chr6 Not Cancer Driver No 1 hippie 47 192 17 17 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 Not Cancer Driver No 1 hippie 54 161 22 22 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 hippie 44 172 11 11 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 Not Cancer Driver No 1 hippie 40 139 0 0 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 intact, hippie 349 1072 195 195 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 2 hippie, biogrid 116 363 48 48 0
SMARCAD1_ENST00000354268 SMARCAD1 Q9H4L7 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 chr4 Not Cancer Driver No 1 hippie 129 388 50 50 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 hippie 64 141 35 35 3
SMARCC1 SMARCC1 Q92922 SWI/SNF complex subunit SMARCC1 chr3 Not Cancer Driver No 1 hippie, biogrid 125 720 81 81 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1 intact, hippie 175 876 133 133 4
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 Census, Compendium Yes 1 hippie, biogrid 48 216 18 18 2
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 Census Yes 1 hippie 47 332 36 36 2
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 hippie 175 539 55 55 0
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 intact, hippie 2 181 2 2 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 Not Cancer Driver No 1 hippie 52 52 9 9 0
SNAI3 SNAI3 Q3KNW1 Zinc finger protein SNAI3 chr16 Not Cancer Driver No 1 hippie 35 67 11 11 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 Not Cancer Driver No 1 intact, hippie 71 231 23 23 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 hippie 130 744 118 118 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 3 intact, hippie 96 599 71 71 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 Not Cancer Driver No 1 hippie 66 587 37 37 0
SPEN SPEN Q96T58 Msx2-interacting protein chr1 Census, Compendium Yes 1 hippie 459 3061 393 393 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 Not Cancer Driver No 1 hippie 46 187 34 34 0
SRPRA SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 intact, hippie 95 232 40 40 0
SS18 SS18 Q15532 Protein SSXT chr18 Census Yes 1 hippie 52 416 52 52 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie 26 114 10 10 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 1 hippie 131 144 25 25 26
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 Not Cancer Driver No 1 hippie 90 178 22 22 2
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 1 hippie 89 125 14 14 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 1 hippie 44 40 5 5 0
SUDS3 SUDS3 Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 chr12 Not Cancer Driver No 5 hippie, biogrid 35 249 28 28 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 2 intact, hippie 59 15 1 1 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 2 hippie, biogrid 83 483 46 46 3
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 Census Yes 1 hippie 96 131 27 27 5
SYNE2_ENST00000344113 SYNE2 Q8WXH0 Nesprin-2 chr14 Not Cancer Driver No 1 intact, hippie 779 1888 220 220 1
TAB2_ENST00000637181 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 Not Cancer Driver No 1 hippie 87 573 73 73 2
TAF1B TAF1B Q53T94 TATA box-binding protein-associated factor RNA polymerase I subunit B chr2 Not Cancer Driver No 1 hippie 61 54 7 7 0
TAF6L TAF6L Q9Y6J9 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L chr11 Not Cancer Driver No 1 hippie 64 246 20 20 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 Not Cancer Driver No 1 hippie 79 288 32 32 2
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 2 intact, hippie 54 305 53 53 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TBC1D32 TBC1D32 Q96NH3 Protein broad-minded chr6 Not Cancer Driver No 2 intact, hippie 173 110 19 19 0
TBL1XR1 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 Census, Compendium Yes 1 hippie, biogrid 82 136 19 19 4
TBP TBP P20226 TATA-box-binding protein chr6 Not Cancer Driver No 1 hippie 40 164 14 14 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 Census, Compendium Yes 1 hippie 123 352 57 57 2
TCF19_ENST00000376255 TCF19 Q9Y242 Transcription factor 19 chr6 Not Cancer Driver No 1 hippie 33 228 24 24 0
TCF20 TCF20 Q9UGU0 Transcription factor 20 chr22 Not Cancer Driver No 1 hippie 234 1811 214 214 1
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 3 hippie, biogrid 54 55 10 10 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 1 hippie 61 285 52 52 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 Not Cancer Driver No 2 hippie, biogrid 82 245 47 47 0
TGIF1 TGIF1 Q15583 Homeobox protein TGIF1 chr18 Compendium Yes 1 hippie 45 309 32 32 5
TGIF2LX_ENST00000283891 TGIF2LX Q8IUE1 Homeobox protein TGIF2LX chrX Not Cancer Driver No 1 hippie, biogrid 117 215 101 101 0
TGIF2_ENST00000611732 TGIF2 Q9GZN2 Homeobox protein TGIF2 chr20 Not Cancer Driver No 1 hippie 37 171 23 23 0
THAP11 THAP11 Q96EK4 THAP domain-containing protein 11 chr16 Not Cancer Driver No 1 hippie 23 207 17 17 0
TIMM13 TIMM13 Q9Y5L4 Mitochondrial import inner membrane translocase subunit Tim13 chr19 Not Cancer Driver No 1 intact, hippie 7 20 1 1 0
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 2 intact, hippie 111 381 53 53 0
TLE3 TLE3 Q04726 Transducin-like enhancer protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 87 381 50 50 0
TLE4_ENST00000376552 TLE4 Q04727 Transducin-like enhancer protein 4 chr9 Not Cancer Driver No 1 hippie 172 381 92 92 0
TLN1 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 intact, hippie 278 1109 126 126 0
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 Not Cancer Driver No 1 hippie 24 6 0 0 0
TMEM54 TMEM54 Q969K7 Transmembrane protein 54 chr1 Not Cancer Driver No 1 hippie 16 0 0 0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 1 hippie 85 625 83 83 0
TNRC18 TNRC18 O15417 Trinucleotide repeat-containing gene 18 protein chr7 Not Cancer Driver No 4 intact, hippie, biogrid 310 2580 271 271 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 150 508 59 59 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 1 hippie 154 543 46 46 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 4 intact, hippie 2891 282 1466 1466 83
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 hippie 82 443 55 55 0
TPD52L1_ENST00000534000 TPD52L1 Q16890 Tumor protein D53 chr6 Not Cancer Driver No 1 hippie, biogrid 46 170 38 38 0
TRAK1 TRAK1 Q9UPV9 Trafficking kinesin-binding protein 1 chr3 Not Cancer Driver No 1 intact, hippie 118 619 74 74 0
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 Not Cancer Driver No 4 intact, hippie, biogrid 226 957 167 167 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie 85 49 7 7 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 intact, hippie 120 537 61 61 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 59 87 11 11 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRMT61A TRMT61A Q96FX7 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A chr14 Not Cancer Driver No 1 intact, hippie, biogrid 16 74 9 9 0
TRPM7 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 Not Cancer Driver No 1 intact, hippie 199 455 60 60 0
TRPS1_ENST00000220888 TRPS1 Q9UHF7 Zinc finger transcription factor Trps1 chr8 Not Cancer Driver No 1 hippie 348 800 216 216 7
TSC22D3_ENST00000372397 TSC22D3 Q99576 TSC22 domain family protein 3 chrX Not Cancer Driver No 1 hippie 18 51 9 9 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 40 63 11 11 5
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 67 53 10 10 12
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 intact, hippie 52 65 11 11 2
TUBB6 TUBB6 Q9BUF5 Tubulin beta-6 chain chr18 Not Cancer Driver No 1 intact, hippie 69 51 5 5 1
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 Not Cancer Driver No 1 hippie 23 132 11 11 7
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 61 77 14 14 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 hippie 86 73 6 6 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 Not Cancer Driver No 1 hippie 100 567 77 77 1
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 Not Cancer Driver No 1 intact, hippie 97 353 49 49 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 88 253 22 22 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 Not Cancer Driver No 1 hippie 161 539 68 68 0
USP37_ENST00000454775 USP37 Q86T82 Ubiquitin carboxyl-terminal hydrolase 37 chr2 Not Cancer Driver No 1 hippie 112 530 62 62 0
USP38 USP38 Q8NB14 Ubiquitin carboxyl-terminal hydrolase 38 chr4 Not Cancer Driver No 1 hippie 94 180 21 21 0
USP43 USP43 Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 chr17 Not Cancer Driver No 1 hippie 134 562 56 56 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 hippie 170 215 45 45 0
VBP1 VBP1 P61758 Prefoldin subunit 3 chrX Not Cancer Driver No 3 intact, hippie, biogrid 27 47 7 7 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR26 WDR26 Q9H7D7 WD repeat-containing protein 26 chr1 Not Cancer Driver No 1 hippie 71 187 9 9 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 5 hippie, biogrid 30 35 3 3 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie 105 203 10 10 39
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 2 intact, hippie, biogrid 148 651 135 135 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 Census, Compendium Yes 1 hippie 164 373 41 41 2
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 intact, hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XYLT2 XYLT2 Q9H1B5 Xylosyltransferase 2 chr17 Not Cancer Driver No 2 intact, hippie 85 264 28 28 1
YAF2_ENST00000534854 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 27 166 27 27 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 1 hippie 37 336 26 26 2
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 Census, Compendium Yes 1 hippie 131 268 50 50 1
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 4 intact, hippie, biogrid 75 216 30 30 0
ZBTB43_ENST00000449886 ZBTB43 O43298 Zinc finger and BTB domain-containing protein 43 chr9 Not Cancer Driver No 1 hippie 56 252 33 33 0
ZBTB5 ZBTB5 O15062 Zinc finger and BTB domain-containing protein 5 chr9 Not Cancer Driver No 1 hippie 79 439 56 56 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 Not Cancer Driver No 1 hippie 60 285 30 30 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 Not Cancer Driver No 1 hippie 299 859 211 211 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 hippie 43 262 34 34 0
ZFP64_ENST00000361387 ZFP64 Q9NTW7 Zinc finger protein 64 chr20 Not Cancer Driver No 1 hippie 105 235 42 42 0
ZFPM2 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 Not Cancer Driver No 1 hippie 374 659 233 233 8
ZFYVE1 ZFYVE1 Q9HBF4 Zinc finger FYVE domain-containing protein 1 chr14 Not Cancer Driver No 1 intact, hippie 97 122 16 16 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 1 intact, hippie 75 346 49 49 0
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 Census Yes 4 hippie, biogrid 144 583 68 68 0
ZMYM3 ZMYM3 Q14202 Zinc finger MYM-type protein 3 chrX Census Yes 3 intact, hippie, biogrid 203 538 90 90 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 Not Cancer Driver No 1 hippie 71 184 26 26 0
ZMYND8_ENST00000311275 ZMYND8 Q9ULU4 Protein kinase C-binding protein 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 176 830 124 124 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 Compendium Yes 1 hippie 125 600 88 88 0
ZNF217 ZNF217 O75362 Zinc finger protein 217 chr20 Not Cancer Driver No 4 intact, hippie, biogrid 169 760 136 136 0
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 44 628 37 37 0
ZNF273 ZNF273 Q14593 Zinc finger protein 273 chr7 Not Cancer Driver No 1 intact, hippie 71 98 13 13 0
ZNF395 ZNF395 Q9H8N7 Zinc finger protein 395 chr8 Not Cancer Driver No 1 hippie 70 342 46 46 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 3 intact, hippie, biogrid 101 694 83 83 0
ZNF516 ZNF516 Q92618 Zinc finger protein 516 chr18 Not Cancer Driver No 3 hippie, biogrid 177 861 131 131 0
ZNF521 ZNF521 Q96K83 Zinc finger protein 521 chr18 Census, Compendium Yes 3 intact, hippie, biogrid 318 365 90 90 0
ZNF592_ENST00000299927 ZNF592 Q92610 Zinc finger protein 592 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 150 856 100 100 0
ZNF608 ZNF608 Q9ULD9 Zinc finger protein 608 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 170 1433 162 162 0
ZNF609 ZNF609 O15014 Zinc finger protein 609 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 141 1333 133 133 0
ZNF639_ENST00000621687 ZNF639 Q9UID6 Zinc finger protein 639 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 61 139 23 23 0
ZNF687 ZNF687 Q8N1G0 Zinc finger protein 687 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 138 776 83 83 1
ZNF76 ZNF76 P36508 Zinc finger protein 76 chr6 Not Cancer Driver No 1 hippie 66 330 39 39 0
ZNF800_ENST00000393312 ZNF800 Q2TB10 Zinc finger protein 800 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 108 397 72 72 0
ZNF827 ZNF827 Q17R98 Zinc finger protein 827 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 158 754 123 123 0