| GO term | GO name | GO namespace | GO def |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0033314 | mitotic DNA replication checkpoint signaling | biological_process | A signal transduction process that contributes to a mitotic DNA replication checkpoint. [GOC:mtg_cell_cycle] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005664 | nuclear origin of replication recognition complex | cellular_component | A multisubunit complex that is located at the replication origins of a chromosome in the nucleus. [GOC:elh] |
| GO:0003688 | DNA replication origin binding | molecular_function | Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. [GOC:curators] |
| GO:0016887 | ATP hydrolysis activity | molecular_function | Catalysis of the reaction |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0006270 | DNA replication initiation | biological_process | The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate. [ISBN:071673706X, ISBN:0815316194, PMID:28209641] |
| GO:0005524 | ATP binding | molecular_function | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
| GO:0000781 | chromosome, telomeric region | cellular_component | The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). [GOC:elh] |
| GO:0003677 | DNA binding | molecular_function | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw] |
| GO:0003682 | chromatin binding | molecular_function | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. [GOC:jl, ISBN:0198506732, PMID:20404130] |
| GO:0000808 | origin recognition complex | cellular_component | A multisubunit complex that is located at the replication origins of a chromosome. [GOC:elh] |