Total number of protein in "GO:0006270" GO term: 29
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0006270 | Census | Yes | 63 | 0.154 | 142 | 26 | 0.183 | 0 |
| CCNE2_ENST00000308108 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:0006270 | Not Cancer Driver | No | 46 | 0.114 | 68 | 9 | 0.132 | 0 |
| CDC34 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | GO:0006270 | Not Cancer Driver | No | 26 | 0.11 | 95 | 11 | 0.116 | 0 |
| CDC45_ENST00000407835 | CDC45 | O75419 | Cell division control protein 45 homolog | chr22 | GO:0006270 | Not Cancer Driver | No | 73 | 0.129 | 66 | 16 | 0.242 | 5 |
| CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | GO:0006270 | Not Cancer Driver | No | 57 | 0.102 | 170 | 15 | 0.088 | 1 |
| GINS3_ENST00000318129 | GINS3 | Q9BRX5 | DNA replication complex GINS protein PSF3 | chr16 | GO:0006270 | Not Cancer Driver | No | 36 | 0.167 | 14 | 0 | 0.0 | 0 |
| GMNC | GMNC | A6NCL1 | Geminin coiled-coil domain-containing protein 1 | chr3 | GO:0006270 | Not Cancer Driver | No | 13 | 0.039 | 203 | 9 | 0.044 | 0 |
| LRWD1 | LRWD1 | Q9UFC0 | Leucine-rich repeat and WD repeat-containing protein 1 | chr7 | GO:0006270 | Not Cancer Driver | No | 75 | 0.116 | 133 | 17 | 0.128 | 0 |
| MCM10 | MCM10 | Q7L590 | Protein MCM10 homolog | chr10 | GO:0006270 | Not Cancer Driver | No | 152 | 0.174 | 535 | 102 | 0.191 | 1 |
| MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | GO:0006270 | Not Cancer Driver | No | 104 | 0.115 | 275 | 38 | 0.138 | 1 |
| MCM3_ENST00000229854 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | GO:0006270 | Not Cancer Driver | No | 92 | 0.114 | 310 | 47 | 0.152 | 0 |
| MCM4 | MCM4 | P33991 | DNA replication licensing factor MCM4 | chr8 | GO:0006270 | Not Cancer Driver | No | 121 | 0.14 | 215 | 35 | 0.163 | 0 |
| MCM5 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | GO:0006270 | Not Cancer Driver | No | 88 | 0.12 | 109 | 20 | 0.183 | 1 |
| MCM6 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | GO:0006270 | Not Cancer Driver | No | 101 | 0.123 | 122 | 13 | 0.107 | 0 |
| MCM7 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | GO:0006270 | Not Cancer Driver | No | 101 | 0.14 | 128 | 22 | 0.172 | 0 |
| NOC3L | NOC3L | Q8WTT2 | Nucleolar complex protein 3 homolog | chr10 | GO:0006270 | Not Cancer Driver | No | 75 | 0.094 | 281 | 29 | 0.103 | 0 |
| ORC1_ENST00000371566 | ORC1 | Q13415 | Origin recognition complex subunit 1 | chr1 | GO:0006270 | Not Cancer Driver | No | 100 | 0.116 | 338 | 46 | 0.136 | 5 |
| ORC2 | ORC2 | Q13416 | Origin recognition complex subunit 2 | chr2 | GO:0006270 | Not Cancer Driver | No | 67 | 0.116 | 248 | 22 | 0.089 | 0 |
| ORC3_ENST00000392844 | ORC3 | Q9UBD5 | Origin recognition complex subunit 3 | chr6 | GO:0006270 | Not Cancer Driver | No | 70 | 0.098 | 63 | 5 | 0.079 | 0 |
| ORC4_ENST00000392857 | ORC4 | O43929 | Origin recognition complex subunit 4 | chr2 | GO:0006270 | Not Cancer Driver | No | 52 | 0.119 | 14 | 2 | 0.143 | 1 |
| ORC5 | ORC5 | O43913 | Origin recognition complex subunit 5 | chr7 | GO:0006270 | Not Cancer Driver | No | 43 | 0.099 | 16 | 2 | 0.125 | 0 |
| ORC6 | ORC6 | Q9Y5N6 | Origin recognition complex subunit 6 | chr16 | GO:0006270 | Not Cancer Driver | No | 23 | 0.091 | 69 | 10 | 0.145 | 1 |
| POLA1_ENST00000379059 | POLA1 | P09884 | DNA polymerase alpha catalytic subunit | chrX | GO:0006270 | Not Cancer Driver | No | 185 | 0.127 | 347 | 45 | 0.13 | 3 |
| POLA2 | POLA2 | Q14181 | DNA polymerase alpha subunit B | chr11 | GO:0006270 | Not Cancer Driver | No | 63 | 0.105 | 102 | 16 | 0.157 | 0 |
| PRIM1 | PRIM1 | P49642 | DNA primase small subunit | chr12 | GO:0006270 | Not Cancer Driver | No | 31 | 0.074 | 22 | 1 | 0.045 | 0 |
| PRIM2 | PRIM2 | P49643 | DNA primase large subunit | chr6 | GO:0006270 | Not Cancer Driver | No | 180 | 0.354 | 69 | 57 | 0.826 | 0 |
| PURA | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0006270 | Not Cancer Driver | No | 22 | 0.068 | 188 | 10 | 0.053 | 6 |
| RPA4 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0006270 | Not Cancer Driver | No | 66 | 0.253 | 58 | 15 | 0.259 | 0 |
| TOPBP1 | TOPBP1 | Q92547 | DNA topoisomerase 2-binding protein 1 | chr3 | GO:0006270 | Not Cancer Driver | No | 169 | 0.111 | 577 | 59 | 0.102 | 0 |