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Total number of protein in "GO:0071407" GO term:  350

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0071407 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0071407 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0071407 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0071407 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0071407 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0071407 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0071407 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0071407 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0071407 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0071407 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0071407 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0071407 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0071407 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0071407 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0071407 Not Cancer Driver No 39 0.16 92 21 0.228 1
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0071407 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0071407 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0071407 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0071407 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0071407 Census Yes 474 0.121 2281 268 0.117 1
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0071407 Not Cancer Driver No 49 0.152 11 1 0.091 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0071407 Not Cancer Driver No 80 0.153 184 39 0.212 113
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0071407 Not Cancer Driver No 59 0.171 61 12 0.197 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0071407 Not Cancer Driver No 161 0.214 98 26 0.265 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0071407 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0071407 Not Cancer Driver No 146 0.225 455 98 0.215 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0071407 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0071407 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0071407 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP8 AQP8 O94778 Aquaporin-8 chr16 GO:0071407 Not Cancer Driver No 49 0.188 0 0 0.0 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0071407 Not Cancer Driver No 75 0.254 12 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0071407 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0071407 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 GO:0071407 Not Cancer Driver No 26 0.138 0 0 0.0 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0071407 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0071407 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0071407 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0071407 Not Cancer Driver No 66 0.119 23 5 0.217 2
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0071407 Census, Compendium Yes 114 0.135 547 77 0.141 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0071407 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0071407 Not Cancer Driver No 22 0.114 34 6 0.176 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0071407 Not Cancer Driver No 13 0.13 21 2 0.095 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0071407 Census Yes 153 0.108 667 70 0.105 8
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0071407 Not Cancer Driver No 73 0.184 139 26 0.187 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0071407 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0071407 Not Cancer Driver No 80 0.132 45 4 0.089 0
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0071407 Not Cancer Driver No 389 0.208 382 76 0.199 6
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0071407 Census Yes 32 0.116 62 5 0.081 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0071407 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0071407 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0071407 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0071407 Census Yes 49 0.118 71 7 0.099 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0071407 Not Cancer Driver No 74 0.185 75 16 0.213 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0071407 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0071407 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0071407 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCDC62 CCDC62 Q6P9F0 Coiled-coil domain-containing protein 62 chr12 GO:0071407 Not Cancer Driver No 104 0.152 344 56 0.163 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0071407 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0071407 Not Cancer Driver No 45 0.104 186 19 0.102 0
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0071407 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0071407 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0071407 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0071407 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0071407 Not Cancer Driver No 3 0.009 276 2 0.007 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0071407 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0071407 Not Cancer Driver No 40 0.083 44 2 0.045 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0071407 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0071407 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0071407 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0071407 Census, Compendium Yes 335 0.617 157 130 0.828 13
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 GO:0071407 Not Cancer Driver No 25 0.134 7 0 0.0 5
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0071407 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 GO:0071407 Not Cancer Driver No 147 0.198 450 90 0.2 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0071407 Not Cancer Driver No 368 0.245 73 22 0.301 140
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0071407 Not Cancer Driver No 61 0.189 0 0 0.0 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0071407 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0071407 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0071407 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0071407 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0071407 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0071407 Not Cancer Driver No 109 0.216 48 8 0.167 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0071407 Not Cancer Driver No 102 0.114 485 61 0.126 4
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0071407 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0071407 Not Cancer Driver No 118 0.128 61 10 0.164 2
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0071407 Compendium Yes 182 0.143 331 42 0.127 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0071407 Not Cancer Driver No 118 0.093 692 57 0.082 1
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0071407 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0071407 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0071407 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0071407 Census, Compendium Yes 194 0.213 371 59 0.159 16
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0071407 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0071407 Not Cancer Driver No 172 0.361 29 18 0.621 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0071407 Not Cancer Driver No 54 0.257 78 21 0.269 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0071407 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0071407 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0071407 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0071407 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0071407 Not Cancer Driver No 78 0.144 501 72 0.144 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0071407 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0071407 Not Cancer Driver No 26 0.12 54 6 0.111 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0071407 Not Cancer Driver No 51 0.119 327 34 0.104 0
EPG5 EPG5 Q9HCE0 Ectopic P granules protein 5 homolog chr18 GO:0071407 Not Cancer Driver No 305 0.118 347 46 0.133 2
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0071407 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0071407 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0071407 Not Cancer Driver No 90 0.17 92 11 0.12 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0071407 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0071407 Census Yes 66 0.113 295 35 0.119 0
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0071407 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0071407 Not Cancer Driver No 10 0.052 32 0 0.0 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0071407 Not Cancer Driver No 54 0.152 0 0 0.0 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0071407 Not Cancer Driver No 12 0.065 61 2 0.033 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0071407 Census Yes 103 0.125 245 34 0.139 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0071407 Not Cancer Driver No 84 0.335 97 51 0.526 7
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0071407 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0071407 Census, Compendium Yes 200 0.201 64 27 0.422 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0071407 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0071407 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0071407 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0071407 Census, Compendium Yes 70 0.104 595 68 0.114 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:0071407 Not Cancer Driver No 58 0.128 103 8 0.078 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0071407 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0071407 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0071407 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0071407 Not Cancer Driver No 188 0.403 19 13 0.684 11
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0071407 Census, Compendium Yes 68 0.165 242 41 0.169 5
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0071407 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0071407 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDAP1 GDAP1 Q8TB36 Ganglioside-induced differentiation-associated protein 1 chr8 GO:0071407 Not Cancer Driver No 51 0.142 78 14 0.179 11
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0071407 Not Cancer Driver No 34 0.15 0 0 0.0 46
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0071407 Not Cancer Driver No 52 0.147 11 3 0.273 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0071407 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0071407 Not Cancer Driver No 17 0.239 12 3 0.25 0
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0071407 Not Cancer Driver No 41 0.138 72 1 0.014 0
GPBAR1_ENST00000521462 GPBAR1 Q8TDU6 G-protein coupled bile acid receptor 1 chr2 GO:0071407 Not Cancer Driver No 30 0.091 22 4 0.182 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0071407 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0071407 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0071407 Not Cancer Driver No 153 0.182 36 9 0.25 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 GO:0071407 Not Cancer Driver No 83 0.115 261 33 0.126 0
GRAMD1B_ENST00000529750 GRAMD1B Q3KR37 Protein Aster-B chr11 GO:0071407 Not Cancer Driver No 140 0.19 335 69 0.206 0
GRAMD1C GRAMD1C Q8IYS0 Protein Aster-C chr3 GO:0071407 Not Cancer Driver No 103 0.156 205 31 0.151 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0071407 Not Cancer Driver No 26 0.119 5 0 0.0 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0071407 Not Cancer Driver No 23 0.18 71 16 0.225 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0071407 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0071407 Not Cancer Driver No 47 0.217 124 29 0.234 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0071407 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0071407 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0071407 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0071407 Not Cancer Driver No 187 0.155 631 58 0.092 3
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0071407 Not Cancer Driver No 46 0.094 145 14 0.097 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0071407 Not Cancer Driver No 92 0.181 29 4 0.138 19
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0071407 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0071407 Not Cancer Driver No 77 0.093 504 45 0.089 0
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0071407 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0071407 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0071407 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0071407 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0071407 Not Cancer Driver No 73 0.112 282 35 0.124 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0071407 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0071407 Census, Compendium Yes 14 0.118 34 4 0.118 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0071407 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0071407 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFIT1B IFIT1B Q5T764 Interferon-induced protein with tetratricopeptide repeats 1B chr10 GO:0071407 Not Cancer Driver No 59 0.124 21 1 0.048 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0071407 Not Cancer Driver No 46 0.246 0 0 0.0 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0071407 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0071407 Not Cancer Driver No 27 0.099 112 17 0.152 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0071407 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0071407 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0071407 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0071407 Not Cancer Driver No 39 0.145 16 3 0.188 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0071407 Not Cancer Driver No 49 0.153 84 12 0.143 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0071407 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0071407 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0071407 Not Cancer Driver No 42 0.094 34 2 0.059 7
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0071407 Not Cancer Driver No 37 0.134 43 1 0.023 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0071407 Not Cancer Driver No 36 0.084 204 21 0.103 1
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0071407 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0071407 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 GO:0071407 Not Cancer Driver No 359 0.133 394 57 0.145 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0071407 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUP JUP P14923 Junction plakoglobin chr17 GO:0071407 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0071407 Not Cancer Driver No 65 0.127 173 21 0.121 3
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0071407 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0071407 Not Cancer Driver No 49 0.257 0 0 0.0 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0071407 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0071407 Not Cancer Driver No 67 0.079 291 28 0.096 3
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0071407 Not Cancer Driver No 114 0.127 405 60 0.148 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0071407 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0071407 Not Cancer Driver No 34 0.139 154 24 0.156 0
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0071407 Not Cancer Driver No 54 0.125 388 46 0.119 0
LEP LEP P41159 Leptin chr7 GO:0071407 Not Cancer Driver No 29 0.174 0 0 0.0 2
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0071407 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0071407 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0071407 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0071407 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0071407 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0071407 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0071407 Not Cancer Driver No 26 0.063 384 25 0.065 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0071407 Not Cancer Driver No 92 0.195 408 81 0.199 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0071407 Not Cancer Driver No 54 0.205 47 13 0.277 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 GO:0071407 Not Cancer Driver No 53 0.141 35 7 0.2 15
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0071407 Not Cancer Driver No 123 0.186 29 6 0.207 2
MSN MSN P26038 Moesin chrX GO:0071407 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSR1 MSR1 P21757 Macrophage scavenger receptor types I and II chr8 GO:0071407 Not Cancer Driver No 167 0.37 241 106 0.44 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0071407 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0071407 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0071407 Not Cancer Driver No 1 0.042 0 0 0.0 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0071407 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0071407 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0071407 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0071407 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0071407 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0071407 Not Cancer Driver No 104 0.107 344 38 0.11 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0071407 Not Cancer Driver No 169 0.163 40 4 0.1 15
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0071407 Not Cancer Driver No 229 0.286 429 114 0.266 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0071407 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0071407 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0071407 Census Yes 83 0.133 298 37 0.124 0
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 GO:0071407 Not Cancer Driver No 141 0.122 998 124 0.124 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0071407 Not Cancer Driver No 107 0.268 58 27 0.466 0
OSBPL7_ENST00000392507 OSBPL7 Q9BZF2 Oxysterol-binding protein-related protein 7 chr17 GO:0071407 Not Cancer Driver No 99 0.118 395 44 0.111 0
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0071407 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0071407 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0071407 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0071407 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY11 P2RY11 Q96G91 P2Y purinoceptor 11 chr19 GO:0071407 Not Cancer Driver No 47 0.126 31 1 0.032 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0071407 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY13 P2RY13 Q9BPV8 P2Y purinoceptor 13 chr3 GO:0071407 Not Cancer Driver No 63 0.178 20 2 0.1 0
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 GO:0071407 Not Cancer Driver No 67 0.178 60 13 0.217 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0071407 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0071407 Not Cancer Driver No 50 0.152 10 5 0.5 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0071407 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0071407 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 GO:0071407 Not Cancer Driver No 58 0.098 340 33 0.097 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0071407 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0071407 Not Cancer Driver No 91 0.142 139 13 0.094 0
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0071407 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0071407 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0071407 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0071407 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0071407 Census Yes 37 0.154 99 22 0.222 2
PDXP PDXP Q96GD0 Chronophin chr22 GO:0071407 Not Cancer Driver No 14 0.047 38 4 0.105 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0071407 Not Cancer Driver No 109 0.408 142 62 0.437 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0071407 Not Cancer Driver No 144 0.192 56 7 0.125 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0071407 Not Cancer Driver No 318 0.289 121 39 0.322 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0071407 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0071407 Not Cancer Driver No 112 0.195 26 5 0.192 101
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0071407 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0071407 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0071407 Not Cancer Driver No 313 0.257 481 104 0.216 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0071407 Not Cancer Driver No 54 0.112 33 7 0.212 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0071407 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0071407 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0071407 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0071407 Not Cancer Driver No 47 0.058 695 35 0.05 0
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0071407 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0071407 Census Yes 53 0.151 24 0 0.0 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0071407 Not Cancer Driver No 110 0.237 78 15 0.192 31
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0071407 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0071407 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0071407 Not Cancer Driver No 105 0.174 30 5 0.167 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0071407 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAE1_ENST00000371242 RAE1 P78406 mRNA export factor RAE1 chr20 GO:0071407 Not Cancer Driver No 64 0.174 73 11 0.151 0
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0071407 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0071407 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0071407 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0071407 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0071407 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0071407 Not Cancer Driver No 158 0.147 589 87 0.148 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0071407 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0071407 Not Cancer Driver No 97 0.105 197 19 0.096 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0071407 Not Cancer Driver No 132 0.133 495 71 0.143 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0071407 Not Cancer Driver No 142 0.129 868 113 0.13 4
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0071407 Not Cancer Driver No 58 0.112 225 21 0.093 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0071407 Not Cancer Driver No 145 0.104 732 81 0.111 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0071407 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0071407 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0071407 Not Cancer Driver No 45 0.086 226 26 0.115 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0071407 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:0071407 Not Cancer Driver No 28 0.115 168 19 0.113 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0071407 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0071407 Not Cancer Driver No 1703 0.343 782 281 0.359 51
RYR3 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0071407 Not Cancer Driver No 1079 0.222 649 162 0.25 0
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0071407 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0071407 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0071407 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0071407 Not Cancer Driver No 129 0.199 57 11 0.193 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0071407 Not Cancer Driver No 51 0.122 57 5 0.088 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0071407 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0071407 Census, Compendium Yes 58 0.135 86 16 0.186 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0071407 Compendium Yes 172 0.135 617 73 0.118 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0071407 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0071407 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC16A1 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 GO:0071407 Not Cancer Driver No 69 0.138 70 3 0.043 3
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0071407 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0071407 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0071407 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0071407 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0071407 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0071407 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0071407 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0071407 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0071407 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0071407 Not Cancer Driver No 89 0.109 251 29 0.116 1
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0071407 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0071407 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0071407 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0071407 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0071407 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0071407 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0071407 Not Cancer Driver No 66 0.142 421 62 0.147 14
SP5 SP5 Q6BEB4 Transcription factor Sp5 chr2 GO:0071407 Not Cancer Driver No 30 0.075 228 22 0.096 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0071407 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0071407 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0071407 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0071407 Not Cancer Driver No 35 0.135 0 0 0.0 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0071407 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0071407 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0071407 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0071407 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0071407 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0071407 Not Cancer Driver No 60 0.165 45 12 0.267 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0071407 Not Cancer Driver No 131 0.175 144 25 0.174 26
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0071407 Not Cancer Driver No 59 0.239 58 12 0.207 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0071407 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0071407 Compendium Yes 61 0.18 285 52 0.182 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0071407 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0071407 Not Cancer Driver No 123 0.179 107 26 0.243 0
TIPARP TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0071407 Not Cancer Driver No 65 0.099 200 20 0.1 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0071407 Not Cancer Driver No 123 0.136 0 0 0.0 1
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0071407 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0071407 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0071407 Not Cancer Driver No 47 0.162 37 7 0.189 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0071407 Not Cancer Driver No 24 0.103 45 3 0.067 0
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0071407 Not Cancer Driver No 226 0.188 957 167 0.175 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0071407 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0071407 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0071407 Not Cancer Driver No 93 0.111 155 18 0.116 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0071407 Not Cancer Driver No 19 0.123 32 4 0.125 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0071407 Not Cancer Driver No 43 0.14 1 0 0.0 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0071407 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT3A2 UGT3A2 Q3SY77 UDP-glucuronosyltransferase 3A2 chr5 GO:0071407 Not Cancer Driver No 169 0.323 0 0 0.0 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0071407 Census, Compendium Yes 122 0.109 602 69 0.115 0
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0071407 Not Cancer Driver No 56 0.144 84 16 0.19 2
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0071407 Not Cancer Driver No 213 0.125 577 65 0.113 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0071407 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0071407 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0071407 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0071407 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0071407 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0071407 Not Cancer Driver No 26 0.044 415 14 0.034 0