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Total number of protein in "GO:0071310" GO term:  981

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0071310 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0071310 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0071310 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0071310 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0071310 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0071310 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCD4 ABCD4 O14678 Lysosomal cobalamin transporter ABCD4 chr14 GO:0071310 Not Cancer Driver No 77 0.127 6 1 0.167 3
ABCG4 ABCG4 Q9H172 ATP-binding cassette sub-family G member 4 chr11 GO:0071310 Not Cancer Driver No 122 0.189 29 7 0.241 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0071310 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0071310 Census, Compendium Yes 171 0.145 641 70 0.109 0
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 GO:0071310 Not Cancer Driver No 97 0.125 287 40 0.139 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0071310 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0071310 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0071310 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0071310 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0071310 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:0071310 Not Cancer Driver No 32 0.077 16 2 0.125 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0071310 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0071310 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 GO:0071310 Not Cancer Driver No 175 0.21 162 26 0.16 0
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 GO:0071310 Not Cancer Driver No 504 0.316 374 128 0.342 0
ADAMTS13 ADAMTS13 Q76LX8 A disintegrin and metalloproteinase with thrombospondin motifs 13 chr9 GO:0071310 Not Cancer Driver No 172 0.121 285 35 0.123 43
ADAMTS7 ADAMTS7 Q9UKP4 A disintegrin and metalloproteinase with thrombospondin motifs 7 chr15 GO:0071310 Not Cancer Driver No 244 0.145 640 100 0.156 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0071310 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0071310 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0071310 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0071310 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0071310 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0071310 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0071310 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0071310 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADNP2 ADNP2 Q6IQ32 Activity-dependent neuroprotector homeobox protein 2 chr18 GO:0071310 Not Cancer Driver No 133 0.118 475 53 0.112 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0071310 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0071310 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0071310 Not Cancer Driver No 85 0.179 33 10 0.303 1
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0071310 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0071310 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0071310 Not Cancer Driver No 88 0.144 166 22 0.133 11
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0071310 Not Cancer Driver No 73 0.213 78 22 0.282 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0071310 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0071310 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0071310 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0071310 Census Yes 474 0.121 2281 268 0.117 1
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0071310 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0071310 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0071310 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0071310 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0071310 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0071310 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0071310 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0071310 Not Cancer Driver No 84 0.127 46 7 0.152 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0071310 Not Cancer Driver No 46 0.093 85 7 0.082 0
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0071310 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0071310 Not Cancer Driver No 59 0.171 61 12 0.197 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0071310 Not Cancer Driver No 161 0.214 98 26 0.265 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0071310 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0071310 Not Cancer Driver No 146 0.225 455 98 0.215 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0071310 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0071310 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0071310 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0071310 Not Cancer Driver No 70 0.105 149 14 0.094 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0071310 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0071310 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP8 AQP8 O94778 Aquaporin-8 chr16 GO:0071310 Not Cancer Driver No 49 0.188 0 0 0.0 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0071310 Not Cancer Driver No 75 0.254 12 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0071310 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0071310 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0071310 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0071310 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0071310 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 GO:0071310 Not Cancer Driver No 162 0.136 769 95 0.124 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0071310 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0071310 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0071310 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0071310 Census Yes 74 0.125 25 1 0.04 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0071310 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0071310 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0071310 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0071310 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0071310 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0071310 Not Cancer Driver No 228 0.152 171 46 0.269 52
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0071310 Not Cancer Driver No 168 0.188 341 64 0.188 0
B3GNT2 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 GO:0071310 Not Cancer Driver No 51 0.128 22 6 0.273 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0071310 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0071310 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0071310 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0071310 Not Cancer Driver No 108 0.124 677 75 0.111 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0071310 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCAT2 BCAT2 O15382 Branched-chain-amino-acid aminotransferase, mitochondrial chr19 GO:0071310 Not Cancer Driver No 54 0.138 19 0 0.0 2
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 GO:0071310 Census, Compendium Yes 210 0.251 677 171 0.253 3
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0071310 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0071310 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0071310 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0071310 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0071310 Census, Compendium Yes 421 0.458 899 408 0.454 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0071310 Not Cancer Driver No 45 0.1 190 19 0.1 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0071310 Not Cancer Driver No 13 0.13 21 2 0.095 0
BHMG1 MEIOSIN C9JSJ3 Meiosis initiator protein chr19 GO:0071310 Not Cancer Driver No 0 0.0 498 0 0.0 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0071310 Census Yes 153 0.108 667 70 0.105 8
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0071310 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0071310 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0071310 Not Cancer Driver No 273 0.359 36 17 0.472 0
BRINP2 BRINP2 Q9C0B6 BMP/retinoic acid-inducible neural-specific protein 2 chr1 GO:0071310 Not Cancer Driver No 271 0.346 13 2 0.154 0
BRINP3 BRINP3 Q76B58 BMP/retinoic acid-inducible neural-specific protein 3 chr1 GO:0071310 Not Cancer Driver No 439 0.573 15 10 0.667 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0071310 Census Yes 174 0.139 397 59 0.149 6
BSPRY BSPRY Q5W0U4 B box and SPRY domain-containing protein chr9 GO:0071310 Not Cancer Driver No 41 0.102 89 5 0.056 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0071310 Census, Compendium Yes 147 0.223 114 27 0.237 110
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0071310 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0071310 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0071310 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0071310 Not Cancer Driver No 75 0.125 396 47 0.119 0
CACTIN CACTIN Q8WUQ7 Cactin chr19 GO:0071310 Not Cancer Driver No 94 0.124 503 54 0.107 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 GO:0071310 Not Cancer Driver No 27 0.118 92 10 0.109 0
CALB1 CALB1 P05937 Calbindin chr8 GO:0071310 Not Cancer Driver No 46 0.176 0 0 0.0 0
CALCRL CALCRL Q16602 Calcitonin gene-related peptide type 1 receptor chr2 GO:0071310 Not Cancer Driver No 122 0.265 8 4 0.5 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0071310 Not Cancer Driver No 25 0.147 48 4 0.083 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0071310 Not Cancer Driver No 81 0.116 46 11 0.239 0
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0071310 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0071310 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0071310 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0071310 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0071310 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0071310 Census Yes 49 0.118 71 7 0.099 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0071310 Not Cancer Driver No 74 0.185 75 16 0.213 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0071310 Not Cancer Driver No 304 0.282 189 60 0.317 108
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:0071310 Not Cancer Driver No 27 0.082 39 5 0.128 0
CASTOR3 CASTOR3 Q8NAP1 Putative protein CASTOR 3 chr7 GO:0071310 Not Cancer Driver No 18 0.11 1 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0071310 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0071310 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0071310 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCDC62 CCDC62 Q6P9F0 Coiled-coil domain-containing protein 62 chr12 GO:0071310 Not Cancer Driver No 104 0.152 344 56 0.163 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0071310 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0071310 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL13 CCL13 Q99616 C-C motif chemokine 13 chr17 GO:0071310 Not Cancer Driver No 15 0.153 1 0 0.0 0
CCL17_ENST00000616880 CCL17 Q92583 C-C motif chemokine 17 chr16 GO:0071310 Not Cancer Driver No 10 0.106 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0071310 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0071310 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0071310 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0071310 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL22 CCL22 O00626 C-C motif chemokine 22 chr16 GO:0071310 Not Cancer Driver No 19 0.204 0 0 0.0 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0071310 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0071310 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0071310 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0071310 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0071310 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0071310 Not Cancer Driver No 45 0.104 186 19 0.102 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0071310 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0071310 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0071310 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD44 CD44 P16070 CD44 antigen chr11 GO:0071310 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0071310 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD58 CD58 P19256 Lymphocyte function-associated antigen 3 chr1 GO:0071310 Compendium Yes 29 0.116 12 2 0.167 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0071310 Not Cancer Driver No 26 0.11 95 11 0.116 0
CDC42EP2 CDC42EP2 O14613 Cdc42 effector protein 2 chr11 GO:0071310 Not Cancer Driver No 19 0.09 162 17 0.105 0
CDC42EP4 CDC42EP4 Q9H3Q1 Cdc42 effector protein 4 chr17 GO:0071310 Not Cancer Driver No 47 0.132 352 47 0.134 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0071310 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0071310 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0071310 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0071310 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0071310 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0071310 Not Cancer Driver No 3 0.009 276 2 0.007 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0071310 Not Cancer Driver No 29 0.083 19 0 0.0 1
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0071310 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0071310 Not Cancer Driver No 40 0.083 44 2 0.045 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0071310 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0071310 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0071310 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0071310 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:0071310 Not Cancer Driver No 24 0.11 195 18 0.092 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0071310 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 GO:0071310 Not Cancer Driver No 25 0.134 7 0 0.0 5
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0071310 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLEC3B CLEC3B P05452 Tetranectin chr3 GO:0071310 Not Cancer Driver No 34 0.168 50 13 0.26 0
CMA1 CMA1 P23946 Chymase chr14 GO:0071310 Not Cancer Driver No 47 0.19 9 1 0.111 0
COL16A1 COL16A1 Q07092 Collagen alpha-1(XVI) chain chr1 GO:0071310 Not Cancer Driver No 192 0.12 1381 163 0.118 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0071310 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 GO:0071310 Not Cancer Driver No 372 0.272 1159 329 0.284 83
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0071310 Census Yes 402 0.274 1182 337 0.285 103
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0071310 Not Cancer Driver No 349 0.209 1457 310 0.213 32
COL4A6_ENST00000372216 COL4A6 Q14031 Collagen alpha-6(IV) chain chrX GO:0071310 Not Cancer Driver No 286 0.169 1451 255 0.176 1
COL5A2 COL5A2 P05997 Collagen alpha-2(V) chain chr2 GO:0071310 Not Cancer Driver No 350 0.233 1276 297 0.233 2
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 GO:0071310 Not Cancer Driver No 145 0.141 434 61 0.141 12
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 GO:0071310 Not Cancer Driver No 147 0.198 450 90 0.2 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0071310 Not Cancer Driver No 51 0.111 126 15 0.119 1
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0071310 Not Cancer Driver No 41 0.084 138 10 0.072 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0071310 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0071310 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0071310 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0071310 Not Cancer Driver No 85 0.117 443 54 0.122 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0071310 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0071310 Not Cancer Driver No 144 0.186 62 10 0.161 15
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0071310 Census Yes 25 0.076 277 23 0.083 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0071310 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0071310 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:0071310 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0071310 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0071310 Not Cancer Driver No 38 0.125 160 25 0.156 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0071310 Census Yes 133 0.137 124 17 0.137 20
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0071310 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 GO:0071310 Not Cancer Driver No 204 0.227 541 120 0.222 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0071310 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX GO:0071310 Not Cancer Driver No 85 0.147 484 72 0.149 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 GO:0071310 Not Cancer Driver No 48 0.108 94 4 0.043 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 GO:0071310 Not Cancer Driver No 45 0.111 49 6 0.122 2
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0071310 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0071310 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSB CTSB P07858 Cathepsin B chr8 GO:0071310 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0071310 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0071310 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0071310 Not Cancer Driver No 54 0.163 0 0 0.0 0
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0071310 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0071310 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0071310 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0071310 Not Cancer Driver No 17 0.172 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0071310 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0071310 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0071310 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0071310 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0071310 Not Cancer Driver No 109 0.216 48 8 0.167 0
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:0071310 Census, Compendium Yes 64 0.185 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0071310 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0071310 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0071310 Not Cancer Driver No 102 0.114 485 61 0.126 4
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0071310 Not Cancer Driver No 193 0.135 114 11 0.096 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0071310 Not Cancer Driver No 56 0.123 82 7 0.085 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0071310 Not Cancer Driver No 48 0.142 53 6 0.113 1
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0071310 Compendium Yes 150 0.319 6 3 0.5 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0071310 Not Cancer Driver No 98 0.204 5 0 0.0 9
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0071310 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0071310 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0071310 Not Cancer Driver No 118 0.128 61 10 0.164 2
DEFB104B DEFB104B Q8WTQ1 Beta-defensin 104 chr8 GO:0071310 Not Cancer Driver No 1 0.014 0 0 0.0 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0071310 Not Cancer Driver No 9 0.127 3 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0071310 Not Cancer Driver No 56 0.144 17 2 0.118 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0071310 Compendium Yes 182 0.143 331 42 0.127 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0071310 Not Cancer Driver No 118 0.093 692 57 0.082 1
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0071310 Not Cancer Driver No 75 0.109 73 15 0.205 7
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0071310 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0071310 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0071310 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0071310 Census, Compendium Yes 194 0.213 371 59 0.159 16
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0071310 Not Cancer Driver No 321 0.153 312 60 0.192 1
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0071310 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0071310 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0071310 Not Cancer Driver No 112 0.121 112 4 0.036 2
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0071310 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0071310 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0071310 Not Cancer Driver No 21 0.114 4 1 0.25 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0071310 Not Cancer Driver No 54 0.257 78 21 0.269 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 GO:0071310 Not Cancer Driver No 43 0.087 211 14 0.066 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0071310 Not Cancer Driver No 49 0.112 272 23 0.085 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0071310 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0071310 Not Cancer Driver No 62 0.145 21 6 0.286 2
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0071310 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:0071310 Not Cancer Driver No 27 0.155 11 1 0.091 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0071310 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFHC2 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX GO:0071310 Not Cancer Driver No 113 0.151 50 10 0.2 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0071310 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0071310 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0071310 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0071310 Compendium Yes 90 0.189 352 59 0.168 11
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0071310 Not Cancer Driver No 60 0.155 252 46 0.183 0
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0071310 Not Cancer Driver No 72 0.135 90 12 0.133 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0071310 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0071310 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0071310 Not Cancer Driver No 26 0.12 54 6 0.111 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0071310 Not Cancer Driver No 118 0.306 117 34 0.291 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0071310 Not Cancer Driver No 51 0.119 327 34 0.104 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0071310 Not Cancer Driver No 11 0.037 61 1 0.016 0
EPG5 EPG5 Q9HCE0 Ectopic P granules protein 5 homolog chr18 GO:0071310 Not Cancer Driver No 305 0.118 347 46 0.133 2
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0071310 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0071310 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0071310 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0071310 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 GO:0071310 Not Cancer Driver No 204 0.135 372 62 0.167 1
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0071310 Not Cancer Driver No 106 0.129 459 54 0.118 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0071310 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0071310 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0071310 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0071310 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0071310 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0071310 Not Cancer Driver No 90 0.17 92 11 0.12 1
ETV3 ETV3 P41162 ETS translocation variant 3 chr1 GO:0071310 Not Cancer Driver No 48 0.094 330 24 0.073 0
EXT2_ENST00000533608 EXT2 Q93063 Exostosin-2 chr11 GO:0071310 Census, Compendium Yes 93 0.13 12 1 0.083 9
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0071310 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0071310 Census Yes 66 0.113 295 35 0.119 0
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0071310 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0071310 Not Cancer Driver No 10 0.052 32 0 0.0 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0071310 Not Cancer Driver No 65 0.231 94 18 0.191 1
FASN FASN P49327 Fatty acid synthase chr17 GO:0071310 Not Cancer Driver No 291 0.116 309 42 0.136 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0071310 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0071310 Not Cancer Driver No 54 0.152 0 0 0.0 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0071310 Census Yes 51 0.165 99 30 0.303 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0071310 Not Cancer Driver No 12 0.065 61 2 0.033 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0071310 Not Cancer Driver No 114 0.139 145 21 0.145 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0071310 Census Yes 103 0.125 245 34 0.139 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0071310 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0071310 Not Cancer Driver No 78 0.225 29 6 0.207 0
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0071310 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0071310 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0071310 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0071310 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0071310 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0071310 Not Cancer Driver No 81 0.179 53 8 0.151 8
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 GO:0071310 Not Cancer Driver No 362 0.139 1183 170 0.144 19
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0071310 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0071310 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0071310 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0071310 Census, Compendium Yes 253 0.186 259 41 0.158 13
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0071310 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0071310 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0071310 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0071310 Census, Compendium Yes 70 0.104 595 68 0.114 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0071310 Not Cancer Driver No 96 0.274 26 5 0.192 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0071310 Not Cancer Driver No 226 0.325 28 11 0.393 16
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0071310 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0071310 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0071310 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0071310 Not Cancer Driver No 90 0.157 22 2 0.091 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:0071310 Not Cancer Driver No 58 0.128 103 8 0.078 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0071310 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0071310 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0071310 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0071310 Not Cancer Driver No 188 0.403 19 13 0.684 11
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0071310 Not Cancer Driver No 39 0.116 24 3 0.125 0
GAREM1 GAREM1 Q9H706 GRB2-associated and regulator of MAPK protein 1 chr18 GO:0071310 Not Cancer Driver No 128 0.146 408 50 0.123 0
GAS1 GAS1 P54826 Growth arrest-specific protein 1 chr9 GO:0071310 Not Cancer Driver No 13 0.038 82 4 0.049 0
GAS2L1_ENST00000621062 GAS2L1 Q99501 GAS2-like protein 1 chr22 GO:0071310 Not Cancer Driver No 76 0.112 474 50 0.105 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0071310 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0071310 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0071310 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0071310 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0071310 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0071310 Not Cancer Driver No 92 0.155 166 27 0.163 0
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 GO:0071310 Not Cancer Driver No 75 0.127 134 15 0.112 0
GBP3 GBP3 Q9H0R5 Guanylate-binding protein 3 chr1 GO:0071310 Not Cancer Driver No 76 0.128 128 15 0.117 0
GBP4 GBP4 Q96PP9 Guanylate-binding protein 4 chr1 GO:0071310 Not Cancer Driver No 114 0.178 165 31 0.188 0
GBP5 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0071310 Not Cancer Driver No 106 0.181 170 21 0.124 0
GBP6 GBP6 Q6ZN66 Guanylate-binding protein 6 chr1 GO:0071310 Not Cancer Driver No 112 0.177 157 21 0.134 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0071310 Not Cancer Driver No 88 0.138 93 8 0.086 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:0071310 Not Cancer Driver No 16 0.034 56 2 0.036 4
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0071310 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0071310 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0071310 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDAP1 GDAP1 Q8TB36 Ganglioside-induced differentiation-associated protein 1 chr8 GO:0071310 Not Cancer Driver No 51 0.142 78 14 0.179 11
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0071310 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 GO:0071310 Not Cancer Driver No 121 0.177 42 8 0.19 0
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0071310 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0071310 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0071310 Not Cancer Driver No 47 0.141 138 17 0.123 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0071310 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0071310 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB3 GJB3 O75712 Gap junction beta-3 protein chr1 GO:0071310 Not Cancer Driver No 48 0.178 13 0 0.0 6
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0071310 Not Cancer Driver No 42 0.161 12 4 0.333 4
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 GO:0071310 Not Cancer Driver No 152 0.149 112 7 0.062 22
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0071310 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:0071310 Not Cancer Driver No 124 0.224 63 14 0.222 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0071310 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0071310 Not Cancer Driver No 106 0.235 58 14 0.241 0
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0071310 Not Cancer Driver No 52 0.147 11 3 0.273 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0071310 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0071310 Not Cancer Driver No 17 0.239 12 3 0.25 0
GNRHR GNRHR P30968 Gonadotropin-releasing hormone receptor chr4 GO:0071310 Not Cancer Driver No 40 0.122 15 1 0.067 14
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0071310 Not Cancer Driver No 41 0.138 72 1 0.014 0
GPBAR1_ENST00000521462 GPBAR1 Q8TDU6 G-protein coupled bile acid receptor 1 chr2 GO:0071310 Not Cancer Driver No 30 0.091 22 4 0.182 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0071310 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0071310 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0071310 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:0071310 Not Cancer Driver No 57 0.153 12 0 0.0 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0071310 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 GO:0071310 Not Cancer Driver No 83 0.115 261 33 0.126 0
GRAMD1B_ENST00000529750 GRAMD1B Q3KR37 Protein Aster-B chr11 GO:0071310 Not Cancer Driver No 140 0.19 335 69 0.206 0
GRAMD1C GRAMD1C Q8IYS0 Protein Aster-C chr3 GO:0071310 Not Cancer Driver No 103 0.156 205 31 0.151 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0071310 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0071310 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0071310 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0071310 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0071310 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0071310 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0071310 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0071310 Not Cancer Driver No 26 0.119 5 0 0.0 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0071310 Not Cancer Driver No 23 0.18 71 16 0.225 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0071310 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0071310 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAS1 HAS1 Q92839 Hyaluronan synthase 1 chr19 GO:0071310 Not Cancer Driver No 115 0.199 9 0 0.0 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0071310 Not Cancer Driver No 100 0.181 17 7 0.412 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0071310 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0071310 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0071310 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0071310 Not Cancer Driver No 187 0.155 631 58 0.092 3
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0071310 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0071310 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 GO:0071310 Not Cancer Driver No 35 0.146 203 29 0.143 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0071310 Not Cancer Driver No 78 0.093 227 25 0.11 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0071310 Not Cancer Driver No 37 0.132 226 32 0.142 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0071310 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0071310 Census Yes 118 0.143 435 51 0.117 0
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0071310 Not Cancer Driver No 138 0.15 77 7 0.091 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0071310 Not Cancer Driver No 37 0.142 30 4 0.133 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0071310 Not Cancer Driver No 92 0.181 29 4 0.138 19
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0071310 Not Cancer Driver No 31 0.093 202 11 0.054 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0071310 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0071310 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA2 HOXA2 O43364 Homeobox protein Hox-A2 chr7 GO:0071310 Not Cancer Driver No 58 0.154 281 48 0.171 1
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0071310 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0071310 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0071310 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0071310 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0071310 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0071310 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0071310 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0071310 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0071310 Compendium Yes 44 0.096 127 9 0.071 2
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0071310 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0071310 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYAL3 HYAL3 O43820 Hyaluronidase-3 chr3 GO:0071310 Not Cancer Driver No 48 0.115 10 0 0.0 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0071310 Not Cancer Driver No 61 0.115 251 28 0.112 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0071310 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0071310 Census, Compendium Yes 14 0.118 34 4 0.118 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0071310 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0071310 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0071310 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFIT1B IFIT1B Q5T764 Interferon-induced protein with tetratricopeptide repeats 1B chr10 GO:0071310 Not Cancer Driver No 59 0.124 21 1 0.048 0
IFIT2_ENST00000371826 IFIT2 P09913 Interferon-induced protein with tetratricopeptide repeats 2 chr10 GO:0071310 Not Cancer Driver No 73 0.155 85 17 0.2 0
IFIT3_ENST00000371811 IFIT3 O14879 Interferon-induced protein with tetratricopeptide repeats 3 chr10 GO:0071310 Not Cancer Driver No 47 0.096 143 11 0.077 0
IFITM2_ENST00000399817 IFITM2 Q01629 Interferon-induced transmembrane protein 2 chr11 GO:0071310 Not Cancer Driver No 23 0.174 17 5 0.294 0
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 GO:0071310 Compendium Yes 55 0.099 50 6 0.12 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0071310 Not Cancer Driver No 46 0.246 0 0 0.0 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0071310 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0071310 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0071310 Not Cancer Driver No 27 0.099 112 17 0.152 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0071310 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0071310 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0071310 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0071310 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0071310 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0071310 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 GO:0071310 Not Cancer Driver No 35 0.17 0 0 0.0 0
IL3RA IL3RA P26951 Interleukin-3 receptor subunit alpha chrX GO:0071310 Not Cancer Driver No 89 0.235 9 2 0.222 0
ILDR1_ENST00000344209 ILDR1 Q86SU0 Immunoglobulin-like domain-containing receptor 1 chr3 GO:0071310 Not Cancer Driver No 112 0.205 260 66 0.254 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0071310 Not Cancer Driver No 49 0.153 84 12 0.143 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 GO:0071310 Not Cancer Driver No 70 0.136 6 1 0.167 0
INA INA Q16352 Alpha-internexin chr10 GO:0071310 Not Cancer Driver No 62 0.124 256 43 0.168 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0071310 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0071310 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0071310 Not Cancer Driver No 42 0.094 34 2 0.059 7
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0071310 Not Cancer Driver No 37 0.134 43 1 0.023 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0071310 Not Cancer Driver No 128 0.117 52 3 0.058 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0071310 Not Cancer Driver No 183 0.11 351 35 0.1 0
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0071310 Not Cancer Driver No 233 0.143 257 36 0.14 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0071310 Compendium Yes 49 0.151 228 31 0.136 2
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0071310 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0071310 Not Cancer Driver No 80 0.188 77 20 0.26 2
IRGC IRGC Q6NXR0 Interferon-inducible GTPase 5 chr19 GO:0071310 Not Cancer Driver No 98 0.212 158 36 0.228 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0071310 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0071310 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0071310 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0071310 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0071310 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0071310 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0071310 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 GO:0071310 Not Cancer Driver No 359 0.133 394 57 0.145 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0071310 Census, Compendium Yes 136 0.12 59 5 0.085 5
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0071310 Not Cancer Driver No 190 0.152 724 113 0.156 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0071310 Census Yes 35 0.106 281 25 0.089 0
JUP JUP P14923 Junction plakoglobin chr17 GO:0071310 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0071310 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0071310 Not Cancer Driver No 65 0.127 173 21 0.121 3
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0071310 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0071310 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0071310 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0071310 Not Cancer Driver No 49 0.257 0 0 0.0 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0071310 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0071310 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0071310 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0071310 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0071310 Census, Compendium Yes 357 0.263 275 55 0.2 2
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0071310 Census, Compendium Yes 237 0.38 57 12 0.211 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 GO:0071310 Not Cancer Driver No 245 0.138 683 113 0.165 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0071310 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0071310 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0071310 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0071310 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0071310 Compendium Yes 77 0.168 366 40 0.109 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0071310 Not Cancer Driver No 34 0.139 154 24 0.156 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0071310 Not Cancer Driver No 90 0.142 50 8 0.16 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0071310 Not Cancer Driver No 77 0.158 0 0 0.0 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0071310 Census Yes 75 0.237 246 67 0.272 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 GO:0071310 Not Cancer Driver No 13 0.081 96 7 0.073 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 GO:0071310 Not Cancer Driver No 12 0.096 0 0 0.0 0
LAMTOR3 LAMTOR3 Q9UHA4 Ragulator complex protein LAMTOR3 chr4 GO:0071310 Not Cancer Driver No 12 0.097 0 0 0.0 0
LAMTOR4 LAMTOR4 Q0VGL1 Ragulator complex protein LAMTOR4 chr7 GO:0071310 Not Cancer Driver No 8 0.081 4 0 0.0 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0071310 Not Cancer Driver No 10 0.11 17 0 0.0 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0071310 Not Cancer Driver No 133 0.113 97 10 0.103 1
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0071310 Not Cancer Driver No 54 0.125 388 46 0.119 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0071310 Not Cancer Driver No 119 0.138 63 3 0.048 104
LDOC1 LDOC1 O95751 Protein LDOC1 chrX GO:0071310 Not Cancer Driver No 48 0.329 23 10 0.435 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0071310 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0071310 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0071310 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0071310 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0071310 Not Cancer Driver No 181 0.259 12 8 0.667 25
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0071310 Not Cancer Driver No 37 0.177 86 12 0.14 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 GO:0071310 Census Yes 35 0.222 14 1 0.071 0
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:0071310 Compendium Yes 44 0.106 172 11 0.064 4
LPL LPL P06858 Lipoprotein lipase chr8 GO:0071310 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0071310 Not Cancer Driver No 54 0.235 2 0 0.0 1
LRCH1_ENST00000389798 LRCH1 Q9Y2L9 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 GO:0071310 Not Cancer Driver No 95 0.13 380 41 0.108 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0071310 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0071310 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0071310 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0071310 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSP1_ENST00000311604 LSP1 P33241 Lymphocyte-specific protein 1 chr11 GO:0071310 Not Cancer Driver No 44 0.13 337 43 0.128 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0071310 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0071310 Census Yes 95 0.186 84 12 0.143 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0071310 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0071310 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0071310 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0071310 Compendium Yes 89 0.212 144 20 0.139 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0071310 Not Cancer Driver No 116 0.139 276 41 0.149 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0071310 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0071310 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0071310 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0071310 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0071310 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0071310 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0071310 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0071310 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 GO:0071310 Not Cancer Driver No 36 0.091 31 4 0.129 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0071310 Not Cancer Driver No 70 0.13 411 58 0.141 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0071310 Not Cancer Driver No 218 0.236 124 33 0.266 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0071310 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0071310 Not Cancer Driver No 101 0.14 128 22 0.172 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0071310 Census, Compendium Yes 56 0.114 297 37 0.125 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0071310 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0071310 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEN1 MEN1 O00255 Menin chr11 GO:0071310 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0071310 Not Cancer Driver No 54 0.205 47 13 0.277 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0071310 Not Cancer Driver No 25 0.104 207 22 0.106 0
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 GO:0071310 Not Cancer Driver No 26 0.168 0 0 0.0 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 GO:0071310 Not Cancer Driver No 53 0.141 35 7 0.2 15
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0071310 Not Cancer Driver No 123 0.186 29 6 0.207 2
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0071310 Not Cancer Driver No 180 0.442 172 76 0.442 0
MRAS_ENST00000423968 MRAS O14807 Ras-related protein M-Ras chr3 GO:0071310 Not Cancer Driver No 27 0.13 50 13 0.26 3
MRC1 MRC1 P22897 Macrophage mannose receptor 1 chr10 GO:0071310 Not Cancer Driver No 40 0.027 126 1 0.008 0
MRPL15 MRPL15 Q9P015 39S ribosomal protein L15, mitochondrial chr8 GO:0071310 Not Cancer Driver No 32 0.108 81 3 0.037 0
MSC MSC O60682 Musculin chr8 GO:0071310 Not Cancer Driver No 47 0.228 173 41 0.237 0
MSN MSN P26038 Moesin chrX GO:0071310 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0071310 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0071310 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0071310 Not Cancer Driver No 9 0.145 0 0 0.0 0
MT1X MT1X P80297 Metallothionein-1X chr16 GO:0071310 Not Cancer Driver No 3 0.049 0 0 0.0 0
MT2A MT2A P02795 Metallothionein-2 chr16 GO:0071310 Not Cancer Driver No 8 0.131 0 0 0.0 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 GO:0071310 Not Cancer Driver No 70 0.118 225 28 0.124 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0071310 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0071310 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0071310 Not Cancer Driver No 62 0.083 582 49 0.084 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0071310 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 GO:0071310 Not Cancer Driver No 111 0.159 506 85 0.168 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0071310 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0071310 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYNN_ENST00000356716 MYNN Q9NPC7 Myoneurin chr3 GO:0071310 Not Cancer Driver No 76 0.125 214 24 0.112 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0071310 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0071310 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0071310 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCL NCL P19338 Nucleolin chr2 GO:0071310 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0071310 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0071310 Not Cancer Driver No 125 0.22 129 29 0.225 1
NDOR1_ENST00000344894 NDOR1 Q9UHB4 NADPH-dependent diflavin oxidoreductase 1 chr9 GO:0071310 Not Cancer Driver No 60 0.101 67 7 0.104 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0071310 Not Cancer Driver No 29 0.201 24 4 0.167 1
NEFH NEFH P12036 Neurofilament heavy polypeptide chr22 GO:0071310 Compendium Yes 114 0.111 871 106 0.122 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0071310 Not Cancer Driver No 62 0.108 153 11 0.072 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0071310 Not Cancer Driver No 84 0.236 202 52 0.257 2
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0071310 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 GO:0071310 Not Cancer Driver No 57 0.123 333 41 0.123 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0071310 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFYB NFYB P25208 Nuclear transcription factor Y subunit beta chr12 GO:0071310 Not Cancer Driver No 23 0.111 94 7 0.074 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0071310 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0071310 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0071310 Not Cancer Driver No 300 0.306 71 20 0.282 9
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0071310 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0071310 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0071310 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0071310 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0071310 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0071310 Not Cancer Driver No 229 0.286 429 114 0.266 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0071310 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0071310 Not Cancer Driver No 63 0.146 185 24 0.13 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0071310 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0071310 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0071310 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0071310 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0071310 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0071310 Census Yes 83 0.133 298 37 0.124 0
NR5A2 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 GO:0071310 Not Cancer Driver No 126 0.233 154 35 0.227 0
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 GO:0071310 Not Cancer Driver No 141 0.122 998 124 0.124 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0071310 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0071310 Not Cancer Driver No 161 0.173 207 45 0.217 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0071310 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0071310 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0071310 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0071310 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUP35 NUP35 Q8NFH5 Nucleoporin NUP35 chr2 GO:0071310 Not Cancer Driver No 39 0.12 209 27 0.129 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0071310 Not Cancer Driver No 67 0.168 71 12 0.169 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0071310 Not Cancer Driver No 22 0.039 52 6 0.115 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0071310 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0071310 Not Cancer Driver No 107 0.268 58 27 0.466 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0071310 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSBPL7_ENST00000392507 OSBPL7 Q9BZF2 Oxysterol-binding protein-related protein 7 chr17 GO:0071310 Not Cancer Driver No 99 0.118 395 44 0.111 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0071310 Not Cancer Driver No 57 0.214 67 17 0.254 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0071310 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0071310 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0071310 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0071310 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0071310 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY11 P2RY11 Q96G91 P2Y purinoceptor 11 chr19 GO:0071310 Not Cancer Driver No 47 0.126 31 1 0.032 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0071310 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 GO:0071310 Not Cancer Driver No 67 0.178 60 13 0.217 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0071310 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0071310 Not Cancer Driver No 50 0.152 10 5 0.5 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0071310 Not Cancer Driver No 61 0.12 79 15 0.19 1
PADI2 PADI2 Q9Y2J8 Protein-arginine deiminase type-2 chr1 GO:0071310 Not Cancer Driver No 121 0.182 60 18 0.3 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0071310 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0071310 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0071310 Not Cancer Driver No 37 0.115 33 3 0.091 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0071310 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0071310 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0071310 Census Yes 84 0.187 291 55 0.189 4
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0071310 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0071310 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCOLCE2 PCOLCE2 Q9UKZ9 Procollagen C-endopeptidase enhancer 2 chr3 GO:0071310 Not Cancer Driver No 102 0.246 25 3 0.12 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0071310 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0071310 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0071310 Not Cancer Driver No 114 0.213 132 30 0.227 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0071310 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0071310 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0071310 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0071310 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0071310 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0071310 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0071310 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0071310 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0071310 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 GO:0071310 Not Cancer Driver No 57 0.113 98 11 0.112 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0071310 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0071310 Not Cancer Driver No 70 0.17 14 2 0.143 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0071310 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0071310 Not Cancer Driver No 14 0.047 38 4 0.105 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 GO:0071310 Not Cancer Driver No 134 0.119 610 82 0.134 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0071310 Not Cancer Driver No 109 0.408 142 62 0.437 0
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:0071310 Not Cancer Driver No 133 0.17 43 10 0.233 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0071310 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0071310 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0071310 Not Cancer Driver No 144 0.192 56 7 0.125 30
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0071310 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIGA PIGA P37287 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A chrX GO:0071310 Not Cancer Driver No 51 0.105 21 0 0.0 13
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0071310 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0071310 Not Cancer Driver No 318 0.289 121 39 0.322 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0071310 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0071310 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0071310 Not Cancer Driver No 112 0.195 26 5 0.192 101
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0071310 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0071310 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0071310 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0071310 Census, Compendium Yes 158 0.122 186 21 0.113 0
PML PML P29590 Protein PML chr15 GO:0071310 Census, Compendium Yes 112 0.127 312 34 0.109 0
PMM1 PMM1 Q92871 Phosphomannomutase 1 chr22 GO:0071310 Not Cancer Driver No 37 0.141 15 0 0.0 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0071310 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0071310 Not Cancer Driver No 86 0.11 115 10 0.087 2
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0071310 Not Cancer Driver No 62 0.092 93 4 0.043 9
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0071310 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0071310 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0071310 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0071310 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0071310 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0071310 Compendium Yes 85 0.163 140 27 0.193 7
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0071310 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRDM5 PRDM5 Q9NQX1 PR domain zinc finger protein 5 chr4 GO:0071310 Not Cancer Driver No 135 0.214 148 41 0.277 1
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0071310 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0071310 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0071310 Census Yes 53 0.151 24 0 0.0 2
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0071310 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0071310 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0071310 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0071310 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0071310 Compendium Yes 118 0.134 246 34 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0071310 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0071310 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0071310 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0071310 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0071310 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0071310 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0071310 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0071310 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0071310 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0071310 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0071310 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0071310 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0071310 Census Yes 42 0.093 12 0 0.0 0
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0071310 Not Cancer Driver No 153 0.143 359 58 0.162 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 GO:0071310 Not Cancer Driver No 30 0.173 3 0 0.0 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0071310 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0071310 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0071310 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0071310 Census, Compendium Yes 535 0.371 299 125 0.418 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0071310 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0071310 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAB20 RAB20 Q9NX57 Ras-related protein Rab-20 chr13 GO:0071310 Not Cancer Driver No 33 0.141 57 8 0.14 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 GO:0071310 Not Cancer Driver No 25 0.124 25 2 0.08 0
RAB43_ENST00000393305 RAB43 Q86YS6 Ras-related protein Rab-43 chr3 GO:0071310 Not Cancer Driver No 26 0.123 14 0 0.0 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0071310 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD23B RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 GO:0071310 Not Cancer Driver No 54 0.132 324 41 0.127 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0071310 Not Cancer Driver No 42 0.124 47 5 0.106 3
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0071310 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0071310 Not Cancer Driver No 18 0.103 34 6 0.176 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0071310 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0071310 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0071310 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0071310 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0071310 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0071310 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0071310 Not Cancer Driver No 158 0.147 589 87 0.148 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0071310 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0071310 Not Cancer Driver No 97 0.105 197 19 0.096 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0071310 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0071310 Not Cancer Driver No 82 0.181 164 24 0.146 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0071310 Not Cancer Driver No 82 0.21 380 81 0.213 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0071310 Not Cancer Driver No 158 0.139 796 115 0.144 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0071310 Not Cancer Driver No 71 0.122 297 37 0.125 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0071310 Not Cancer Driver No 132 0.133 495 71 0.143 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0071310 Compendium Yes 75 0.136 400 48 0.12 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0071310 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0071310 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFX2_ENST00000359161 RFX2 P48378 DNA-binding protein RFX2 chr19 GO:0071310 Not Cancer Driver No 79 0.109 301 30 0.1 0
RHEX RHEX Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein chr1 GO:0071310 Not Cancer Driver No 35 0.203 116 27 0.233 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0071310 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0071310 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0071310 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0071310 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0071310 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0071310 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNMT_ENST00000543302 RNMT O43148 mRNA cap guanine-N7 methyltransferase chr18 GO:0071310 Not Cancer Driver No 67 0.141 159 23 0.145 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0071310 Not Cancer Driver No 145 0.104 732 81 0.111 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0071310 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 GO:0071310 Not Cancer Driver No 107 0.228 87 22 0.253 1
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0071310 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 GO:0071310 Not Cancer Driver No 27 0.133 33 2 0.061 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0071310 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 GO:0071310 Not Cancer Driver No 34 0.084 79 3 0.038 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 GO:0071310 Not Cancer Driver No 16 0.11 14 1 0.071 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0071310 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0071310 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0071310 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0071310 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0071310 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 GO:0071310 Compendium Yes 29 0.073 61 1 0.016 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0071310 Not Cancer Driver No 42 0.105 83 5 0.06 0
RUFY4_ENST00000344321 RUFY4 Q6ZNE9 RUN and FYVE domain-containing protein 4 chr2 GO:0071310 Not Cancer Driver No 77 0.135 307 51 0.166 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0071310 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:0071310 Not Cancer Driver No 28 0.115 168 19 0.113 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0071310 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0071310 Not Cancer Driver No 1703 0.343 782 281 0.359 51
RYR3 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0071310 Not Cancer Driver No 1079 0.222 649 162 0.25 0
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 GO:0071310 Not Cancer Driver No 164 0.224 412 100 0.243 0
SBNO2 SBNO2 Q9Y2G9 Protein strawberry notch homolog 2 chr19 GO:0071310 Not Cancer Driver No 108 0.079 456 29 0.064 0
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0071310 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0071310 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0071310 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0071310 Not Cancer Driver No 129 0.199 57 11 0.193 0
SELPLG_ENST00000550948 SELPLG Q14242 P-selectin glycoprotein ligand 1 chr12 GO:0071310 Not Cancer Driver No 68 0.165 297 48 0.162 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0071310 Not Cancer Driver No 136 0.132 456 72 0.158 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0071310 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0071310 Not Cancer Driver No 51 0.122 57 5 0.088 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0071310 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0071310 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0071310 Not Cancer Driver No 84 0.171 44 4 0.091 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0071310 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFR1 SFR1 Q86XK3 Swi5-dependent recombination DNA repair protein 1 homolog chr10 GO:0071310 Not Cancer Driver No 21 0.086 109 12 0.11 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0071310 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0071310 Census, Compendium Yes 58 0.135 86 16 0.186 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0071310 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0071310 Not Cancer Driver No 143 0.148 241 43 0.178 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0071310 Not Cancer Driver No 76 0.216 214 50 0.234 0
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0071310 Not Cancer Driver No 51 0.106 32 7 0.219 0
SHPK SHPK Q9UHJ6 Sedoheptulokinase chr17 GO:0071310 Not Cancer Driver No 44 0.092 31 1 0.032 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0071310 Compendium Yes 172 0.135 617 73 0.118 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0071310 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0071310 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0071310 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0071310 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0071310 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0071310 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0071310 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0071310 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC23A2 SLC23A2 Q9UGH3 Solute carrier family 23 member 2 chr20 GO:0071310 Not Cancer Driver No 87 0.134 76 8 0.105 0
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0071310 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0071310 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0071310 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0071310 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0071310 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC2A5 SLC2A5 P22732 Solute carrier family 2, facilitated glucose transporter member 5 chr1 GO:0071310 Not Cancer Driver No 73 0.146 12 4 0.333 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0071310 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0071310 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC38A9 SLC38A9 Q8NBW4 Sodium-coupled neutral amino acid transporter 9 chr5 GO:0071310 Not Cancer Driver No 57 0.102 33 2 0.061 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0071310 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0071310 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0071310 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0071310 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0071310 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0071310 Not Cancer Driver No 428 0.28 31 13 0.419 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0071310 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0071310 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0071310 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 GO:0071310 Census, Compendium Yes 48 0.093 216 18 0.083 2
SMO SMO Q99835 Smoothened homolog chr7 GO:0071310 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0071310 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0071310 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0071310 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0071310 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX10_ENST00000396376 SNX10 Q9Y5X0 Sorting nexin-10 chr7 GO:0071310 Not Cancer Driver No 24 0.119 52 8 0.154 4
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0071310 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0071310 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0071310 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0071310 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0071310 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOST SOST Q9BQB4 Sclerostin chr17 GO:0071310 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOX1 SOX1 O00570 Transcription factor SOX-1 chr13 GO:0071310 Not Cancer Driver No 26 0.066 304 25 0.082 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0071310 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0071310 Compendium Yes 81 0.196 378 59 0.156 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0071310 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0071310 Compendium Yes 86 0.169 495 82 0.166 18
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0071310 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0071310 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0071310 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPOCK2_ENST00000317376 SPOCK2 Q92563 Testican-2 chr10 GO:0071310 Not Cancer Driver No 48 0.113 113 8 0.071 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0071310 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0071310 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0071310 Not Cancer Driver No 34 0.114 134 20 0.149 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0071310 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0071310 Not Cancer Driver No 35 0.135 0 0 0.0 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0071310 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRF SRF P11831 Serum response factor chr6 GO:0071310 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRM SRM P19623 Spermidine synthase chr1 GO:0071310 Not Cancer Driver No 27 0.089 23 0 0.0 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 GO:0071310 Census Yes 31 0.189 125 27 0.216 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 GO:0071310 Not Cancer Driver No 40 0.168 175 26 0.149 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0071310 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0071310 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0071310 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0071310 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0071310 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0071310 Not Cancer Driver No 60 0.165 45 12 0.267 0
ST3GAL6_ENST00000394162 ST3GAL6 Q9Y274 Type 2 lactosamine alpha-2,3-sialyltransferase chr3 GO:0071310 Not Cancer Driver No 52 0.157 0 0 0.0 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0071310 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0071310 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0071310 Census, Compendium Yes 93 0.118 144 19 0.132 5
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0071310 Not Cancer Driver No 59 0.239 58 12 0.207 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 GO:0071310 Not Cancer Driver No 74 0.136 270 39 0.144 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0071310 Not Cancer Driver No 64 0.117 182 19 0.104 0
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0071310 Not Cancer Driver No 34 0.19 122 23 0.189 0
STRA8 STRA8 Q7Z7C7 Stimulated by retinoic acid gene 8 protein homolog chr7 GO:0071310 Not Cancer Driver No 45 0.136 105 15 0.143 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0071310 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 GO:0071310 Not Cancer Driver No 32 0.136 98 10 0.102 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0071310 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0071310 Not Cancer Driver No 59 0.1 64 9 0.141 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0071310 Not Cancer Driver No 78 0.141 211 24 0.114 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0071310 Not Cancer Driver No 31 0.088 221 22 0.1 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0071310 Not Cancer Driver No 93 0.149 285 39 0.137 0
SYNGR1 SYNGR1 O43759 Synaptogyrin-1 chr22 GO:0071310 Not Cancer Driver No 26 0.112 48 5 0.104 0
SYP SYP P08247 Synaptophysin chrX GO:0071310 Not Cancer Driver No 36 0.115 93 8 0.086 1
TAC1 TAC1 P20366 Protachykinin-1 chr7 GO:0071310 Not Cancer Driver No 31 0.24 18 4 0.222 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0071310 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0071310 Not Cancer Driver No 42 0.099 302 26 0.086 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0071310 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0071310 Not Cancer Driver No 70 0.131 348 50 0.144 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0071310 Not Cancer Driver No 39 0.207 25 2 0.08 0
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 GO:0071310 Not Cancer Driver No 66 0.148 220 31 0.141 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0071310 Not Cancer Driver No 31 0.145 73 6 0.082 0
TEX14 TEX14 Q8IWB6 Inactive serine/threonine-protein kinase TEX14 chr17 GO:0071310 Not Cancer Driver No 214 0.143 872 115 0.132 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0071310 Compendium Yes 61 0.18 285 52 0.182 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0071310 Census Yes 89 0.117 80 6 0.075 1
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0071310 Not Cancer Driver No 123 0.179 107 26 0.243 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0071310 Not Cancer Driver No 61 0.116 149 21 0.141 38
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0071310 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0071310 Not Cancer Driver No 154 0.127 367 51 0.139 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0071310 Not Cancer Driver No 43 0.204 3 1 0.333 5
TLE4_ENST00000376552 TLE4 Q04727 Transducin-like enhancer protein 4 chr9 GO:0071310 Not Cancer Driver No 172 0.223 381 92 0.241 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0071310 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0071310 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0071310 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0071310 Not Cancer Driver No 99 0.124 1 0 0.0 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0071310 Not Cancer Driver No 101 0.176 458 89 0.194 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0071310 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0071310 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0071310 Not Cancer Driver No 47 0.162 37 7 0.189 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0071310 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0071310 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0071310 Not Cancer Driver No 28 0.153 1 0 0.0 0
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0071310 Not Cancer Driver No 32 0.133 134 20 0.149 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0071310 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0071310 Census Yes 311 0.132 1990 266 0.134 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0071310 Not Cancer Driver No 59 0.205 244 54 0.221 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0071310 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0071310 Not Cancer Driver No 226 0.188 957 167 0.175 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0071310 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0071310 Census, Compendium Yes 120 0.114 537 61 0.114 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0071310 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0071310 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0071310 Not Cancer Driver No 86 0.176 47 15 0.319 0
TROVE2 RO60 P10155 RNA-binding protein RO60 chr1 GO:0071310 Not Cancer Driver No 82 0.152 17 1 0.059 0
TRPA1 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0071310 Not Cancer Driver No 324 0.29 62 14 0.226 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0071310 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0071310 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0071310 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0071310 Census Yes 128 0.168 38 9 0.237 39
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 GO:0071310 Not Cancer Driver No 41 0.091 52 9 0.173 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0071310 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWISTNB POLR1F Q3B726 DNA-directed RNA polymerase I subunit RPA43 chr7 GO:0071310 Not Cancer Driver No 55 0.163 146 29 0.199 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0071310 Not Cancer Driver No 95 0.139 135 11 0.081 38
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0071310 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0071310 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0071310 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0071310 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0071310 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0071310 Not Cancer Driver No 172 0.098 228 30 0.132 0
UBXN2A UBXN2A P68543 UBX domain-containing protein 2A chr2 GO:0071310 Not Cancer Driver No 37 0.143 58 11 0.19 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0071310 Not Cancer Driver No 43 0.14 1 0 0.0 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0071310 Not Cancer Driver No 31 0.1 11 3 0.273 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0071310 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT3A2 UGT3A2 Q3SY77 UDP-glucuronosyltransferase 3A2 chr5 GO:0071310 Not Cancer Driver No 169 0.323 0 0 0.0 0
UMODL1_ENST00000408910 UMODL1 Q5DID0 Uromodulin-like 1 chr21 GO:0071310 Not Cancer Driver No 191 0.145 249 29 0.116 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0071310 Not Cancer Driver No 214 0.135 448 77 0.172 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0071310 Not Cancer Driver No 146 0.129 329 36 0.109 0
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 GO:0071310 Not Cancer Driver No 34 0.128 7 0 0.0 21
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 GO:0071310 Not Cancer Driver No 92 0.115 425 49 0.115 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0071310 Census, Compendium Yes 122 0.109 602 69 0.115 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0071310 Not Cancer Driver No 11 0.11 17 1 0.059 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0071310 Not Cancer Driver No 188 0.254 110 28 0.255 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0071310 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0071310 Not Cancer Driver No 128 0.305 37 12 0.324 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0071310 Not Cancer Driver No 124 0.15 222 38 0.171 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0071310 Not Cancer Driver No 84 0.18 316 57 0.18 1
VPS26B VPS26B Q4G0F5 Vacuolar protein sorting-associated protein 26B chr11 GO:0071310 Not Cancer Driver No 45 0.134 52 5 0.096 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0071310 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0071310 Not Cancer Driver No 63 0.113 445 49 0.11 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0071310 Not Cancer Driver No 26 0.1 102 6 0.059 1
WDR35 WDR35 Q9P2L0 WD repeat-containing protein 35 chr2 GO:0071310 Not Cancer Driver No 137 0.116 42 3 0.071 6
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0071310 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0071310 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0071310 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0071310 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0071310 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0071310 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0071310 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0071310 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0071310 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0071310 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 GO:0071310 Not Cancer Driver No 50 0.142 27 5 0.185 0
WNT9A WNT9A O14904 Protein Wnt-9a chr1 GO:0071310 Not Cancer Driver No 74 0.203 44 11 0.25 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0071310 Not Cancer Driver No 47 0.132 11 4 0.364 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0071310 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0071310 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0071310 Not Cancer Driver No 20 0.175 35 5 0.143 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0071310 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0071310 Not Cancer Driver No 213 0.125 577 65 0.113 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0071310 Not Cancer Driver No 51 0.101 489 49 0.1 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0071310 Not Cancer Driver No 41 0.127 312 41 0.131 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0071310 Not Cancer Driver No 65 0.12 62 10 0.161 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0071310 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0071310 Compendium Yes 151 0.204 433 80 0.185 4
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0071310 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0071310 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0071310 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0071310 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0071310 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0071310 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:0071310 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF236_ENST00000253159 ZNF236 Q9UL36 Zinc finger protein 236 chr18 GO:0071310 Not Cancer Driver No 270 0.146 977 152 0.156 0
ZNF35 ZNF35 P13682 Zinc finger protein 35 chr3 GO:0071310 Not Cancer Driver No 66 0.125 192 17 0.089 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0071310 Not Cancer Driver No 26 0.044 415 14 0.034 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0071310 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZYX ZYX Q15942 Zyxin chr7 GO:0071310 Not Cancer Driver No 83 0.145 385 52 0.135 0