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Total number of protein in "GO:0051716" GO term:  1694

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A3GALT2 A3GALT2 U3KPV4 Alpha-1,3-galactosyltransferase 2 chr1 GO:0051716 Not Cancer Driver No 16 0.047 0 0 0.0 0
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0051716 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0051716 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0051716 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0051716 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0051716 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABCD4 ABCD4 O14678 Lysosomal cobalamin transporter ABCD4 chr14 GO:0051716 Not Cancer Driver No 77 0.127 6 1 0.167 3
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0051716 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABCG4 ABCG4 Q9H172 ATP-binding cassette sub-family G member 4 chr11 GO:0051716 Not Cancer Driver No 122 0.189 29 7 0.241 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0051716 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0051716 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABTB2 ABTB2 Q8N961 Ankyrin repeat and BTB/POZ domain-containing protein 2 chr11 GO:0051716 Not Cancer Driver No 95 0.093 215 20 0.093 0
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 GO:0051716 Not Cancer Driver No 97 0.125 287 40 0.139 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0051716 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0051716 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACER1 ACER1 Q8TDN7 Alkaline ceramidase 1 chr19 GO:0051716 Not Cancer Driver No 54 0.205 0 0 0.0 0
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0051716 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0051716 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 GO:0051716 Not Cancer Driver No 70 0.186 48 14 0.292 84
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0051716 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0051716 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0051716 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:0051716 Not Cancer Driver No 32 0.077 16 2 0.125 0
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0051716 Not Cancer Driver No 63 0.104 163 23 0.141 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0051716 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0051716 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0051716 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 GO:0051716 Not Cancer Driver No 175 0.21 162 26 0.16 0
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 GO:0051716 Not Cancer Driver No 504 0.316 374 128 0.342 0
ADAMTS13 ADAMTS13 Q76LX8 A disintegrin and metalloproteinase with thrombospondin motifs 13 chr9 GO:0051716 Not Cancer Driver No 172 0.121 285 35 0.123 43
ADAMTS7 ADAMTS7 Q9UKP4 A disintegrin and metalloproteinase with thrombospondin motifs 7 chr15 GO:0051716 Not Cancer Driver No 244 0.145 640 100 0.156 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0051716 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0051716 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0051716 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0051716 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0051716 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0051716 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0051716 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0051716 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0051716 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0051716 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0051716 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0051716 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADNP2 ADNP2 Q6IQ32 Activity-dependent neuroprotector homeobox protein 2 chr18 GO:0051716 Not Cancer Driver No 133 0.118 475 53 0.112 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0051716 Not Cancer Driver No 32 0.088 49 4 0.082 1
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0051716 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0051716 Not Cancer Driver No 49 0.107 48 4 0.083 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0051716 Not Cancer Driver No 41 0.178 2 0 0.0 0
AGAP3_ENST00000622464 AGAP3 Q96P47 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 chr7 GO:0051716 Not Cancer Driver No 116 0.133 404 55 0.136 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0051716 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0051716 Not Cancer Driver No 85 0.179 33 10 0.303 1
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0051716 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0051716 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0051716 Not Cancer Driver No 88 0.144 166 22 0.133 11
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0051716 Not Cancer Driver No 73 0.213 78 22 0.282 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0051716 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0051716 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0051716 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0051716 Census Yes 474 0.121 2281 268 0.117 1
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0051716 Not Cancer Driver No 52 0.165 19 1 0.053 0
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0051716 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0051716 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0051716 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0051716 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0051716 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0051716 Census Yes 77 0.16 84 9 0.107 2
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0051716 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0051716 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0051716 Not Cancer Driver No 84 0.127 46 7 0.152 0
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0051716 Not Cancer Driver No 17 0.106 1 0 0.0 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0051716 Not Cancer Driver No 173 0.133 788 103 0.131 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0051716 Not Cancer Driver No 46 0.093 85 7 0.082 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0051716 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0051716 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0051716 Not Cancer Driver No 34 0.094 192 18 0.094 0
ANKZF1 ANKZF1 Q9H8Y5 Ankyrin repeat and zinc finger domain-containing protein 1 chr2 GO:0051716 Not Cancer Driver No 77 0.106 507 57 0.112 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0051716 Not Cancer Driver No 59 0.171 61 12 0.197 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0051716 Not Cancer Driver No 161 0.214 98 26 0.265 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0051716 Not Cancer Driver No 127 0.102 17 1 0.059 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0051716 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0051716 Not Cancer Driver No 64 0.125 407 57 0.14 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0051716 Not Cancer Driver No 146 0.225 455 98 0.215 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0051716 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0051716 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0051716 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0051716 Not Cancer Driver No 34 0.18 13 2 0.154 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0051716 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0051716 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0051716 Not Cancer Driver No 70 0.105 149 14 0.094 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0051716 Not Cancer Driver No 36 0.101 101 6 0.059 9
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0051716 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP10 AQP10 Q96PS8 Aquaporin-10 chr1 GO:0051716 Not Cancer Driver No 73 0.243 15 1 0.067 0
AQP2 AQP2 P41181 Aquaporin-2 chr12 GO:0051716 Not Cancer Driver No 52 0.192 31 3 0.097 28
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0051716 Not Cancer Driver No 34 0.116 12 0 0.0 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0051716 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP5 AQP5 P55064 Aquaporin-5 chr12 GO:0051716 Not Cancer Driver No 31 0.117 21 2 0.095 5
AQP8 AQP8 O94778 Aquaporin-8 chr16 GO:0051716 Not Cancer Driver No 49 0.188 0 0 0.0 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0051716 Not Cancer Driver No 75 0.254 12 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0051716 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0051716 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0051716 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARHGEF10L ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0051716 Census, Compendium Yes 155 0.121 431 47 0.109 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0051716 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0051716 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 GO:0051716 Not Cancer Driver No 162 0.136 769 95 0.124 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0051716 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0051716 Not Cancer Driver No 71 0.113 332 40 0.12 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0051716 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0051716 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0051716 Not Cancer Driver No 81 0.144 11 0 0.0 3
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0051716 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0051716 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0051716 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0051716 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0051716 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0051716 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATG10 ATG10 Q9H0Y0 Ubiquitin-like-conjugating enzyme ATG10 chr5 GO:0051716 Not Cancer Driver No 22 0.1 9 1 0.111 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0051716 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0051716 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0051716 Compendium Yes 77 0.11 53 8 0.151 6
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0051716 Census Yes 74 0.125 25 1 0.04 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0051716 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0051716 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0051716 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0051716 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0051716 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0051716 Not Cancer Driver No 130 0.13 147 16 0.109 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0051716 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0051716 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0051716 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0051716 Not Cancer Driver No 8 0.075 85 7 0.082 0
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX GO:0051716 Not Cancer Driver No 67 0.143 0 0 0.0 4
ATP6V0A2 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 GO:0051716 Not Cancer Driver No 88 0.103 36 6 0.167 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 GO:0051716 Not Cancer Driver No 40 0.114 0 0 0.0 0
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 GO:0051716 Not Cancer Driver No 86 0.139 31 2 0.065 4
ATP6V1G1 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 GO:0051716 Not Cancer Driver No 12 0.102 91 8 0.088 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0051716 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0051716 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0051716 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0051716 Not Cancer Driver No 41 0.1 122 13 0.107 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0051716 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0051716 Not Cancer Driver No 105 0.251 68 25 0.368 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0051716 Not Cancer Driver No 168 0.188 341 64 0.188 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0051716 Census, Compendium Yes 34 0.286 5 1 0.2 2
B3GNT2 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 GO:0051716 Not Cancer Driver No 51 0.128 22 6 0.273 0
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 GO:0051716 Not Cancer Driver No 52 0.136 0 0 0.0 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0051716 Not Cancer Driver No 55 0.11 53 5 0.094 0
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 GO:0051716 Not Cancer Driver No 105 0.143 328 39 0.119 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0051716 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0051716 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0051716 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0051716 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0051716 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0051716 Not Cancer Driver No 38 0.18 58 9 0.155 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0051716 Census Yes 96 0.124 384 49 0.128 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0051716 Not Cancer Driver No 28 0.224 119 25 0.21 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0051716 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0051716 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0051716 Not Cancer Driver No 108 0.124 677 75 0.111 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0051716 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCAT2 BCAT2 O15382 Branched-chain-amino-acid aminotransferase, mitochondrial chr19 GO:0051716 Not Cancer Driver No 54 0.138 19 0 0.0 2
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0051716 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 GO:0051716 Census, Compendium Yes 210 0.251 677 171 0.253 3
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0051716 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0051716 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0051716 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0051716 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0051716 Census Yes 44 0.097 259 23 0.089 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0051716 Census, Compendium Yes 421 0.458 899 408 0.454 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0051716 Not Cancer Driver No 45 0.1 190 19 0.1 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0051716 Not Cancer Driver No 13 0.13 21 2 0.095 0
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0051716 Not Cancer Driver No 12 0.063 183 12 0.066 0
BHMG1 MEIOSIN C9JSJ3 Meiosis initiator protein chr19 GO:0051716 Not Cancer Driver No 0 0.0 498 0 0.0 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0051716 Census Yes 153 0.108 667 70 0.105 8
BMF_ENST00000561360 BMF Q96LC9 Bcl-2-modifying factor chr15 GO:0051716 Not Cancer Driver No 22 0.12 94 9 0.096 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0051716 Not Cancer Driver No 95 0.185 226 51 0.226 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0051716 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0051716 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0051716 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0051716 Not Cancer Driver No 39 0.123 74 7 0.095 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0051716 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0051716 Not Cancer Driver No 273 0.359 36 17 0.472 0
BRINP2 BRINP2 Q9C0B6 BMP/retinoic acid-inducible neural-specific protein 2 chr1 GO:0051716 Not Cancer Driver No 271 0.346 13 2 0.154 0
BRINP3 BRINP3 Q76B58 BMP/retinoic acid-inducible neural-specific protein 3 chr1 GO:0051716 Not Cancer Driver No 439 0.573 15 10 0.667 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0051716 Census Yes 174 0.139 397 59 0.149 6
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0051716 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0051716 Not Cancer Driver No 90 0.122 321 39 0.121 0
BSPRY BSPRY Q5W0U4 B box and SPRY domain-containing protein chr9 GO:0051716 Not Cancer Driver No 41 0.102 89 5 0.056 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0051716 Census, Compendium Yes 147 0.223 114 27 0.237 110
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:0051716 Not Cancer Driver No 61 0.137 35 6 0.171 0
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 GO:0051716 Not Cancer Driver No 91 0.136 632 88 0.139 0
C2orf40 ECRG4 Q9H1Z8 Augurin chr2 GO:0051716 Not Cancer Driver No 37 0.25 23 11 0.478 0
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0051716 Not Cancer Driver No 31 0.091 43 5 0.116 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0051716 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0051716 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0051716 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0051716 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0051716 Not Cancer Driver No 75 0.125 396 47 0.119 0
CACTIN CACTIN Q8WUQ7 Cactin chr19 GO:0051716 Not Cancer Driver No 94 0.124 503 54 0.107 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 GO:0051716 Not Cancer Driver No 27 0.118 92 10 0.109 0
CALCRL CALCRL Q16602 Calcitonin gene-related peptide type 1 receptor chr2 GO:0051716 Not Cancer Driver No 122 0.265 8 4 0.5 0
CALR CALR P27797 Calreticulin chr19 GO:0051716 Census Yes 45 0.108 245 31 0.127 0
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0051716 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0051716 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0051716 Not Cancer Driver No 25 0.147 48 4 0.083 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0051716 Not Cancer Driver No 81 0.116 46 11 0.239 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0051716 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0051716 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:0051716 Not Cancer Driver No 93 0.128 503 63 0.125 0
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0051716 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0051716 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0051716 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0051716 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP5_ENST00000260315 CASP5 P51878 Caspase-5 chr11 GO:0051716 Not Cancer Driver No 103 0.237 61 17 0.279 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0051716 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0051716 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP8AP2 CASP8AP2 Q9UKL3 CASP8-associated protein 2 chr6 GO:0051716 Not Cancer Driver No 219 0.11 1501 178 0.119 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0051716 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0051716 Census Yes 49 0.118 71 7 0.099 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0051716 Not Cancer Driver No 74 0.185 75 16 0.213 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0051716 Not Cancer Driver No 304 0.282 189 60 0.317 108
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:0051716 Not Cancer Driver No 27 0.082 39 5 0.128 0
CASTOR3 CASTOR3 Q8NAP1 Putative protein CASTOR 3 chr7 GO:0051716 Not Cancer Driver No 18 0.11 1 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0051716 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0051716 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0051716 Not Cancer Driver No 61 0.111 160 19 0.119 103
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0051716 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCDC115 CCDC115 Q96NT0 Coiled-coil domain-containing protein 115 chr2 GO:0051716 Not Cancer Driver No 21 0.117 89 8 0.09 2
CCDC47_ENST00000403162 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 GO:0051716 Not Cancer Driver No 49 0.101 265 23 0.087 0
CCDC62 CCDC62 Q6P9F0 Coiled-coil domain-containing protein 62 chr12 GO:0051716 Not Cancer Driver No 104 0.152 344 56 0.163 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0051716 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0051716 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL13 CCL13 Q99616 C-C motif chemokine 13 chr17 GO:0051716 Not Cancer Driver No 15 0.153 1 0 0.0 0
CCL17_ENST00000616880 CCL17 Q92583 C-C motif chemokine 17 chr16 GO:0051716 Not Cancer Driver No 10 0.106 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0051716 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0051716 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0051716 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0051716 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL22 CCL22 O00626 C-C motif chemokine 22 chr16 GO:0051716 Not Cancer Driver No 19 0.204 0 0 0.0 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0051716 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0051716 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0051716 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0051716 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0051716 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0051716 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0051716 Census, Compendium Yes 55 0.186 31 25 0.806 0
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 GO:0051716 Not Cancer Driver No 42 0.112 60 5 0.083 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0051716 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0051716 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0051716 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD44 CD44 P16070 CD44 antigen chr11 GO:0051716 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0051716 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD58 CD58 P19256 Lymphocyte function-associated antigen 3 chr1 GO:0051716 Compendium Yes 29 0.116 12 2 0.167 0
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 GO:0051716 Not Cancer Driver No 27 0.113 0 0 0.0 0
CD68 CD68 P34810 Macrosialin chr17 GO:0051716 Not Cancer Driver No 26 0.073 192 13 0.068 0
CD69 CD69 Q07108 Early activation antigen CD69 chr12 GO:0051716 Not Cancer Driver No 32 0.161 18 3 0.167 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0051716 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD9 CD9 P21926 CD9 antigen chr12 GO:0051716 Not Cancer Driver No 22 0.096 0 0 0.0 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0051716 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDC25A CDC25A P30304 M-phase inducer phosphatase 1 chr3 GO:0051716 Not Cancer Driver No 63 0.12 313 35 0.112 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0051716 Not Cancer Driver No 26 0.11 95 11 0.116 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 GO:0051716 Not Cancer Driver No 52 0.138 214 31 0.145 0
CDC42EP2 CDC42EP2 O14613 Cdc42 effector protein 2 chr11 GO:0051716 Not Cancer Driver No 19 0.09 162 17 0.105 0
CDC42EP4 CDC42EP4 Q9H3Q1 Cdc42 effector protein 4 chr17 GO:0051716 Not Cancer Driver No 47 0.132 352 47 0.134 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0051716 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0051716 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0051716 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0051716 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0051716 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0051716 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0051716 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0051716 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0051716 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0051716 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0051716 Not Cancer Driver No 15 0.109 67 3 0.045 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0051716 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0051716 Not Cancer Driver No 3 0.009 276 2 0.007 0
CER1 CER1 O95813 Cerberus chr9 GO:0051716 Not Cancer Driver No 70 0.262 119 27 0.227 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0051716 Not Cancer Driver No 29 0.083 19 0 0.0 1
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0051716 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0051716 Not Cancer Driver No 40 0.083 44 2 0.045 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0051716 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0051716 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0051716 Not Cancer Driver No 30 0.135 49 5 0.102 0
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0051716 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0051716 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0051716 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:0051716 Not Cancer Driver No 24 0.11 195 18 0.092 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0051716 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0051716 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0051716 Not Cancer Driver No 74 0.099 116 9 0.078 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0051716 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 GO:0051716 Not Cancer Driver No 25 0.134 7 0 0.0 5
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0051716 Not Cancer Driver No 43 0.196 32 3 0.094 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0051716 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0051716 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0051716 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0051716 Not Cancer Driver No 24 0.095 49 4 0.082 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0051716 Not Cancer Driver No 83 0.098 458 38 0.083 0
CMA1 CMA1 P23946 Chymase chr14 GO:0051716 Not Cancer Driver No 47 0.19 9 1 0.111 0
CNN2_ENST00000263097 CNN2 Q99439 Calponin-2 chr19 GO:0051716 Not Cancer Driver No 35 0.113 166 23 0.139 0
COL16A1 COL16A1 Q07092 Collagen alpha-1(XVI) chain chr1 GO:0051716 Not Cancer Driver No 192 0.12 1381 163 0.118 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0051716 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 GO:0051716 Not Cancer Driver No 372 0.272 1159 329 0.284 83
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0051716 Census Yes 402 0.274 1182 337 0.285 103
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0051716 Not Cancer Driver No 349 0.209 1457 310 0.213 32
COL4A6_ENST00000372216 COL4A6 Q14031 Collagen alpha-6(IV) chain chrX GO:0051716 Not Cancer Driver No 286 0.169 1451 255 0.176 1
COL5A2 COL5A2 P05997 Collagen alpha-2(V) chain chr2 GO:0051716 Not Cancer Driver No 350 0.233 1276 297 0.233 2
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 GO:0051716 Not Cancer Driver No 145 0.141 434 61 0.141 12
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 GO:0051716 Not Cancer Driver No 147 0.198 450 90 0.2 0
COMT COMT P21964 Catechol O-methyltransferase chr22 GO:0051716 Not Cancer Driver No 21 0.077 5 0 0.0 0
COPS9_ENST00000607357 COPS9 Q8WXC6 COP9 signalosome complex subunit 9 chr2 GO:0051716 Not Cancer Driver No 6 0.105 25 3 0.12 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0051716 Not Cancer Driver No 51 0.111 126 15 0.119 1
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0051716 Not Cancer Driver No 41 0.084 138 10 0.072 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0051716 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0051716 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB2_ENST00000507071 CPEB2 Q7Z5Q1 Cytoplasmic polyadenylation element-binding protein 2 chr4 GO:0051716 Not Cancer Driver No 66 0.112 269 17 0.063 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0051716 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0051716 Not Cancer Driver No 85 0.117 443 54 0.122 0
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:0051716 Not Cancer Driver No 74 0.138 80 7 0.087 0
CPNE2_ENST00000535318 CPNE2 Q96FN4 Copine-2 chr16 GO:0051716 Not Cancer Driver No 62 0.113 32 4 0.125 0
CPNE3 CPNE3 O75131 Copine-3 chr8 GO:0051716 Not Cancer Driver No 79 0.147 33 5 0.152 0
CPNE4_ENST00000511604 CPNE4 Q96A23 Copine-4 chr3 GO:0051716 Not Cancer Driver No 135 0.242 33 7 0.212 0
CPNE5 CPNE5 Q9HCH3 Copine-5 chr6 GO:0051716 Not Cancer Driver No 78 0.132 83 8 0.096 0
CPNE6_ENST00000397016 CPNE6 O95741 Copine-6 chr14 GO:0051716 Not Cancer Driver No 85 0.153 111 22 0.198 0
CPNE7 CPNE7 Q9UBL6 Copine-7 chr16 GO:0051716 Not Cancer Driver No 71 0.112 50 6 0.12 0
CPNE8 CPNE8 Q86YQ8 Copine-8 chr12 GO:0051716 Not Cancer Driver No 102 0.181 40 12 0.3 0
CPNE9 CPNE9 Q8IYJ1 Copine-9 chr3 GO:0051716 Not Cancer Driver No 81 0.146 63 11 0.175 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0051716 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0051716 Not Cancer Driver No 144 0.186 62 10 0.161 15
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:0051716 Not Cancer Driver No 35 0.176 45 5 0.111 1
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0051716 Census Yes 25 0.076 277 23 0.083 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0051716 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0051716 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0051716 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0051716 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0051716 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:0051716 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRIP1_ENST00000409393 CRIP1 P50238 Cysteine-rich protein 1 chr14 GO:0051716 Not Cancer Driver No 6 0.078 8 1 0.125 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0051716 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0051716 Not Cancer Driver No 38 0.125 160 25 0.156 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0051716 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0051716 Not Cancer Driver No 72 0.121 100 12 0.12 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0051716 Not Cancer Driver No 22 0.126 59 11 0.186 4
CRYGD CRYGD P07320 Gamma-crystallin D chr2 GO:0051716 Not Cancer Driver No 28 0.161 0 0 0.0 6
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0051716 Census Yes 133 0.137 124 17 0.137 20
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0051716 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 GO:0051716 Not Cancer Driver No 204 0.227 541 120 0.222 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0051716 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSPG5 CSPG5 O95196 Chondroitin sulfate proteoglycan 5 chr3 GO:0051716 Not Cancer Driver No 75 0.133 397 46 0.116 0
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX GO:0051716 Not Cancer Driver No 85 0.147 484 72 0.149 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 GO:0051716 Not Cancer Driver No 48 0.108 94 4 0.043 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 GO:0051716 Not Cancer Driver No 45 0.111 49 6 0.122 2
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0051716 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0051716 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSB CTSB P07858 Cathepsin B chr8 GO:0051716 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0051716 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0051716 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0051716 Not Cancer Driver No 54 0.163 0 0 0.0 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0051716 Not Cancer Driver No 138 0.151 207 38 0.184 2
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0051716 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0051716 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0051716 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0051716 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0051716 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0051716 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYP11B1 CYP11B1 P15538 Cytochrome P450 11B1, mitochondrial chr8 GO:0051716 Not Cancer Driver No 177 0.352 7 1 0.143 50
CYP11B2 CYP11B2 P19099 Cytochrome P450 11B2, mitochondrial chr8 GO:0051716 Not Cancer Driver No 148 0.294 6 0 0.0 6
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0051716 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0051716 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0051716 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0051716 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0051716 Not Cancer Driver No 109 0.216 48 8 0.167 0
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:0051716 Census, Compendium Yes 64 0.185 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0051716 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0051716 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0051716 Not Cancer Driver No 102 0.114 485 61 0.126 4
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0051716 Not Cancer Driver No 193 0.135 114 11 0.096 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0051716 Not Cancer Driver No 56 0.123 82 7 0.085 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0051716 Census, Compendium Yes 106 0.143 549 81 0.148 0
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0051716 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0051716 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0051716 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0051716 Not Cancer Driver No 48 0.142 53 6 0.113 1
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0051716 Compendium Yes 150 0.319 6 3 0.5 0
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0051716 Not Cancer Driver No 14 0.082 88 9 0.102 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0051716 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0051716 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0051716 Not Cancer Driver No 98 0.204 5 0 0.0 9
DDI1 DDI1 Q8WTU0 Protein DDI1 homolog 1 chr11 GO:0051716 Not Cancer Driver No 151 0.381 166 73 0.44 0
DDI2 DDI2 Q5TDH0 Protein DDI1 homolog 2 chr1 GO:0051716 Not Cancer Driver No 47 0.118 187 30 0.16 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0051716 Census Yes 29 0.172 160 27 0.169 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0051716 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0051716 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0051716 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0051716 Not Cancer Driver No 118 0.128 61 10 0.164 2
DEFB104B DEFB104B Q8WTQ1 Beta-defensin 104 chr8 GO:0051716 Not Cancer Driver No 1 0.014 0 0 0.0 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0051716 Not Cancer Driver No 9 0.127 3 0 0.0 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0051716 Not Cancer Driver No 28 0.112 11 1 0.091 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0051716 Not Cancer Driver No 56 0.144 17 2 0.118 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0051716 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0051716 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0051716 Compendium Yes 182 0.143 331 42 0.127 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0051716 Not Cancer Driver No 118 0.093 692 57 0.082 1
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 GO:0051716 Not Cancer Driver No 224 0.257 303 107 0.353 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0051716 Not Cancer Driver No 116 0.16 232 55 0.237 0
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0051716 Not Cancer Driver No 75 0.109 73 15 0.205 7
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0051716 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0051716 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:0051716 Census, Compendium Yes 35 0.103 196 26 0.133 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 GO:0051716 Not Cancer Driver No 110 0.139 36 3 0.083 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0051716 Not Cancer Driver No 60 0.119 131 17 0.13 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0051716 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0051716 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0051716 Census, Compendium Yes 194 0.213 371 59 0.159 16
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0051716 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0051716 Not Cancer Driver No 54 0.131 41 6 0.146 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0051716 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0051716 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0051716 Not Cancer Driver No 112 0.121 112 4 0.036 2
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0051716 Not Cancer Driver No 49 0.14 210 25 0.119 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0051716 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0051716 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0051716 Not Cancer Driver No 21 0.114 4 1 0.25 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0051716 Not Cancer Driver No 54 0.257 78 21 0.269 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 GO:0051716 Not Cancer Driver No 43 0.087 211 14 0.066 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0051716 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0051716 Not Cancer Driver No 122 0.134 554 70 0.126 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0051716 Not Cancer Driver No 104 0.114 284 33 0.116 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0051716 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0051716 Not Cancer Driver No 69 0.119 54 3 0.056 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0051716 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0051716 Not Cancer Driver No 62 0.145 21 6 0.286 2
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0051716 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 GO:0051716 Not Cancer Driver No 40 0.142 153 22 0.144 0
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:0051716 Not Cancer Driver No 27 0.155 11 1 0.091 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0051716 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFHC2 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX GO:0051716 Not Cancer Driver No 113 0.151 50 10 0.2 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0051716 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 GO:0051716 Compendium Yes 132 0.136 179 30 0.168 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0051716 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0051716 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0051716 Not Cancer Driver No 60 0.155 252 46 0.183 0
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0051716 Not Cancer Driver No 72 0.135 90 12 0.133 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0051716 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF2A EIF2A Q9BY44 Eukaryotic translation initiation factor 2A chr3 GO:0051716 Not Cancer Driver No 51 0.087 162 19 0.117 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0051716 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0051716 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0051716 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0051716 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0051716 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0051716 Not Cancer Driver No 26 0.12 54 6 0.111 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0051716 Not Cancer Driver No 118 0.306 117 34 0.291 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0051716 Not Cancer Driver No 51 0.119 327 34 0.104 0
EME1_ENST00000338165 EME1 Q96AY2 Crossover junction endonuclease EME1 chr17 GO:0051716 Not Cancer Driver No 56 0.098 296 30 0.101 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0051716 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENG ENG P17813 Endoglin chr9 GO:0051716 Not Cancer Driver No 60 0.091 114 15 0.132 32
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0051716 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0051716 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPG5 EPG5 Q9HCE0 Ectopic P granules protein 5 homolog chr18 GO:0051716 Not Cancer Driver No 305 0.118 347 46 0.133 2
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0051716 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0051716 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0051716 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0051716 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:0051716 Not Cancer Driver No 27 0.14 9 1 0.111 1
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 GO:0051716 Not Cancer Driver No 204 0.135 372 62 0.167 1
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0051716 Not Cancer Driver No 106 0.129 459 54 0.118 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0051716 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0051716 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0051716 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0051716 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0051716 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0051716 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0051716 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0051716 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0051716 Not Cancer Driver No 25 0.063 53 8 0.151 7
ERLIN1 ERLIN1 O75477 Erlin-1 chr10 GO:0051716 Not Cancer Driver No 29 0.083 46 4 0.087 1
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 GO:0051716 Not Cancer Driver No 38 0.112 22 3 0.136 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0051716 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0051716 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0051716 Not Cancer Driver No 48 0.103 32 5 0.156 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0051716 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0051716 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0051716 Not Cancer Driver No 90 0.17 92 11 0.12 1
ETV3 ETV3 P41162 ETS translocation variant 3 chr1 GO:0051716 Not Cancer Driver No 48 0.094 330 24 0.073 0
EXT2_ENST00000533608 EXT2 Q93063 Exostosin-2 chr11 GO:0051716 Census, Compendium Yes 93 0.13 12 1 0.083 9
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0051716 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0051716 Census Yes 66 0.113 295 35 0.119 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0051716 Not Cancer Driver No 47 0.157 72 15 0.208 0
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0051716 Not Cancer Driver No 34 0.268 0 0 0.0 0
FABP4 FABP4 P15090 Fatty acid-binding protein, adipocyte chr8 GO:0051716 Not Cancer Driver No 14 0.106 4 0 0.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0051716 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0051716 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 GO:0051716 Not Cancer Driver No 78 0.128 169 23 0.136 5
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0051716 Not Cancer Driver No 10 0.052 32 0 0.0 0
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0051716 Not Cancer Driver No 53 0.164 78 11 0.141 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0051716 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0051716 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0051716 Not Cancer Driver No 268 0.131 898 128 0.143 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0051716 Census, Compendium Yes 55 0.164 62 18 0.29 22
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0051716 Not Cancer Driver No 65 0.231 94 18 0.191 1
FASN FASN P49327 Fatty acid synthase chr17 GO:0051716 Not Cancer Driver No 291 0.116 309 42 0.136 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0051716 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0051716 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0051716 Not Cancer Driver No 33 0.098 19 0 0.0 4
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0051716 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0051716 Not Cancer Driver No 54 0.152 0 0 0.0 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0051716 Not Cancer Driver No 55 0.142 68 7 0.103 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0051716 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0051716 Census Yes 51 0.165 99 30 0.303 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0051716 Not Cancer Driver No 12 0.065 61 2 0.033 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0051716 Not Cancer Driver No 114 0.139 145 21 0.145 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0051716 Census Yes 103 0.125 245 34 0.139 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0051716 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0051716 Not Cancer Driver No 78 0.225 29 6 0.207 0
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0051716 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0051716 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0051716 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0051716 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0051716 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0051716 Not Cancer Driver No 81 0.179 53 8 0.151 8
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0051716 Not Cancer Driver No 75 0.111 224 23 0.103 0
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 GO:0051716 Not Cancer Driver No 362 0.139 1183 170 0.144 19
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0051716 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0051716 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0051716 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0051716 Census, Compendium Yes 253 0.186 259 41 0.158 13
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0051716 Not Cancer Driver No 124 0.196 327 70 0.214 3
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0051716 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0051716 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOS FOS P01100 Protein c-Fos chr14 GO:0051716 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSB FOSB P53539 Protein FosB chr19 GO:0051716 Not Cancer Driver No 50 0.148 313 44 0.141 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0051716 Compendium Yes 70 0.153 258 34 0.132 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0051716 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0051716 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0051716 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0051716 Census, Compendium Yes 70 0.104 595 68 0.114 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0051716 Not Cancer Driver No 96 0.274 26 5 0.192 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0051716 Not Cancer Driver No 226 0.325 28 11 0.393 16
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0051716 Not Cancer Driver No 16 0.076 73 0 0.0 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0051716 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0051716 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0051716 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0051716 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0051716 Not Cancer Driver No 90 0.157 22 2 0.091 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0051716 Not Cancer Driver No 9 0.077 11 0 0.0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 GO:0051716 Not Cancer Driver No 19 0.162 10 1 0.1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 GO:0051716 Not Cancer Driver No 11 0.094 2 1 0.5 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:0051716 Not Cancer Driver No 58 0.128 103 8 0.078 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0051716 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0051716 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0051716 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0051716 Not Cancer Driver No 188 0.403 19 13 0.684 11
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0051716 Not Cancer Driver No 10 0.061 39 5 0.128 0
GAP43_ENST00000305124 GAP43 P17677 Neuromodulin chr3 GO:0051716 Not Cancer Driver No 79 0.332 238 79 0.332 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0051716 Not Cancer Driver No 39 0.116 24 3 0.125 0
GAREM1 GAREM1 Q9H706 GRB2-associated and regulator of MAPK protein 1 chr18 GO:0051716 Not Cancer Driver No 128 0.146 408 50 0.123 0
GAS1 GAS1 P54826 Growth arrest-specific protein 1 chr9 GO:0051716 Not Cancer Driver No 13 0.038 82 4 0.049 0
GAS2L1_ENST00000621062 GAS2L1 Q99501 GAS2-like protein 1 chr22 GO:0051716 Not Cancer Driver No 76 0.112 474 50 0.105 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0051716 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0051716 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0051716 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0051716 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0051716 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0051716 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0051716 Not Cancer Driver No 92 0.155 166 27 0.163 0
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 GO:0051716 Not Cancer Driver No 75 0.127 134 15 0.112 0
GBP3 GBP3 Q9H0R5 Guanylate-binding protein 3 chr1 GO:0051716 Not Cancer Driver No 76 0.128 128 15 0.117 0
GBP4 GBP4 Q96PP9 Guanylate-binding protein 4 chr1 GO:0051716 Not Cancer Driver No 114 0.178 165 31 0.188 0
GBP5 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0051716 Not Cancer Driver No 106 0.181 170 21 0.124 0
GBP6 GBP6 Q6ZN66 Guanylate-binding protein 6 chr1 GO:0051716 Not Cancer Driver No 112 0.177 157 21 0.134 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0051716 Not Cancer Driver No 88 0.138 93 8 0.086 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:0051716 Not Cancer Driver No 16 0.034 56 2 0.036 4
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0051716 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0051716 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0051716 Not Cancer Driver No 32 0.117 31 3 0.097 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0051716 Not Cancer Driver No 327 0.122 117 16 0.137 0
GCNA GCNA Q96QF7 Germ cell nuclear acidic protein chrX GO:0051716 Not Cancer Driver No 155 0.224 513 122 0.238 0
GDAP1 GDAP1 Q8TB36 Ganglioside-induced differentiation-associated protein 1 chr8 GO:0051716 Not Cancer Driver No 51 0.142 78 14 0.179 11
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0051716 Not Cancer Driver No 65 0.15 288 42 0.146 62
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0051716 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 GO:0051716 Not Cancer Driver No 121 0.177 42 8 0.19 0
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0051716 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0051716 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0051716 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0051716 Not Cancer Driver No 47 0.141 138 17 0.123 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0051716 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0051716 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB3 GJB3 O75712 Gap junction beta-3 protein chr1 GO:0051716 Not Cancer Driver No 48 0.178 13 0 0.0 6
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0051716 Not Cancer Driver No 42 0.161 12 4 0.333 4
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 GO:0051716 Not Cancer Driver No 152 0.149 112 7 0.062 22
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0051716 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:0051716 Not Cancer Driver No 124 0.224 63 14 0.222 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0051716 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0051716 Not Cancer Driver No 106 0.235 58 14 0.241 0
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0051716 Not Cancer Driver No 12 0.073 10 1 0.1 0
GML GML Q99445 Glycosyl-phosphatidylinositol-anchored molecule-like protein chr8 GO:0051716 Not Cancer Driver No 49 0.31 12 6 0.5 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 GO:0051716 Census, Compendium Yes 48 0.134 10 0 0.0 5
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0051716 Not Cancer Driver No 52 0.147 11 3 0.273 0
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0051716 Not Cancer Driver No 43 0.123 39 6 0.154 3
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0051716 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 GO:0051716 Not Cancer Driver No 60 0.152 16 1 0.062 1
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0051716 Not Cancer Driver No 17 0.239 12 3 0.25 0
GNRHR GNRHR P30968 Gonadotropin-releasing hormone receptor chr4 GO:0051716 Not Cancer Driver No 40 0.122 15 1 0.067 14
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0051716 Not Cancer Driver No 41 0.138 72 1 0.014 0
GPBAR1_ENST00000521462 GPBAR1 Q8TDU6 G-protein coupled bile acid receptor 1 chr2 GO:0051716 Not Cancer Driver No 30 0.091 22 4 0.182 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0051716 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0051716 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0051716 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:0051716 Not Cancer Driver No 57 0.153 12 0 0.0 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0051716 Not Cancer Driver No 42 0.115 45 1 0.022 1
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0051716 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0051716 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 GO:0051716 Not Cancer Driver No 83 0.115 261 33 0.126 0
GRAMD1B_ENST00000529750 GRAMD1B Q3KR37 Protein Aster-B chr11 GO:0051716 Not Cancer Driver No 140 0.19 335 69 0.206 0
GRAMD1C GRAMD1C Q8IYS0 Protein Aster-C chr3 GO:0051716 Not Cancer Driver No 103 0.156 205 31 0.151 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0051716 Not Cancer Driver No 28 0.129 10 1 0.1 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0051716 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0051716 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0051716 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0051716 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRK1 GRK1 Q15835 Rhodopsin kinase GRK1 chr13 GO:0051716 Not Cancer Driver No 70 0.124 32 2 0.062 2
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 GO:0051716 Not Cancer Driver No 346 0.29 339 91 0.268 3
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0051716 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0051716 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0051716 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0051716 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0051716 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0051716 Not Cancer Driver No 26 0.108 18 1 0.056 0
GSTO2 GSTO2 Q9H4Y5 Glutathione S-transferase omega-2 chr10 GO:0051716 Not Cancer Driver No 25 0.103 17 0 0.0 0
GTF2H5 GTF2H5 Q6ZYL4 General transcription factor IIH subunit 5 chr6 GO:0051716 Not Cancer Driver No 7 0.099 0 0 0.0 1
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 GO:0051716 Not Cancer Driver No 91 0.126 660 85 0.129 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0051716 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCY1B1_ENST00000264424 GUCY1B1 Q02153 Guanylate cyclase soluble subunit beta-1 chr4 GO:0051716 Not Cancer Driver No 103 0.166 83 20 0.241 0
H2AFX H2AX P16104 Histone H2AX chr11 GO:0051716 Not Cancer Driver No 20 0.14 68 10 0.147 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0051716 Not Cancer Driver No 23 0.18 71 16 0.225 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 GO:0051716 Not Cancer Driver No 32 0.077 413 32 0.077 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0051716 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0051716 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAS1 HAS1 Q92839 Hyaluronan synthase 1 chr19 GO:0051716 Not Cancer Driver No 115 0.199 9 0 0.0 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0051716 Not Cancer Driver No 100 0.181 17 7 0.412 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0051716 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0051716 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0051716 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0051716 Not Cancer Driver No 187 0.155 631 58 0.092 3
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0051716 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0051716 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0051716 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0051716 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 GO:0051716 Not Cancer Driver No 35 0.146 203 29 0.143 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0051716 Not Cancer Driver No 78 0.093 227 25 0.11 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0051716 Not Cancer Driver No 37 0.132 226 32 0.142 0
HESX1 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 GO:0051716 Not Cancer Driver No 32 0.173 59 9 0.153 6
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0051716 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0051716 Compendium Yes 233 0.32 43 16 0.372 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0051716 Not Cancer Driver No 37 0.106 77 9 0.117 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0051716 Census Yes 118 0.143 435 51 0.117 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0051716 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 GO:0051716 Not Cancer Driver No 21 0.162 61 10 0.164 0
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0051716 Not Cancer Driver No 138 0.15 77 7 0.091 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0051716 Not Cancer Driver No 37 0.142 30 4 0.133 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0051716 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 GO:0051716 Census Yes 6 0.056 107 6 0.056 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0051716 Census Yes 12 0.11 109 12 0.11 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0051716 Not Cancer Driver No 92 0.181 29 4 0.138 19
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0051716 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0051716 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0051716 Not Cancer Driver No 31 0.093 202 11 0.054 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0051716 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0051716 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA2 HOXA2 O43364 Homeobox protein Hox-A2 chr7 GO:0051716 Not Cancer Driver No 58 0.154 281 48 0.171 1
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0051716 Not Cancer Driver No 24 0.124 42 4 0.095 3
HRAS HRAS P01112 GTPase HRas chr11 GO:0051716 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0051716 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSBP1L1 HSBP1L1 C9JCN9 Heat shock factor-binding protein 1-like protein 1 chr18 GO:0051716 Not Cancer Driver No 6 0.081 66 5 0.076 0
HSBP1_ENST00000570259 HSBP1 O75506 Heat shock factor-binding protein 1 chr16 GO:0051716 Not Cancer Driver No 6 0.079 76 6 0.079 0
HSD17B1_ENST00000585807 HSD17B1 P14061 17-beta-hydroxysteroid dehydrogenase type 1 chr17 GO:0051716 Not Cancer Driver No 48 0.146 59 28 0.475 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0051716 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 GO:0051716 Not Cancer Driver No 52 0.156 23 3 0.13 1
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0051716 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0051716 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0051716 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0051716 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0051716 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 GO:0051716 Not Cancer Driver No 112 0.174 235 27 0.115 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0051716 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0051716 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0051716 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0051716 Compendium Yes 44 0.096 127 9 0.071 2
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 GO:0051716 Not Cancer Driver No 25 0.089 17 2 0.118 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0051716 Not Cancer Driver No 669 0.153 2091 329 0.157 21
HVCN1_ENST00000620084 HVCN1 Q96D96 Voltage-gated hydrogen channel 1 chr12 GO:0051716 Not Cancer Driver No 51 0.187 52 13 0.25 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0051716 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0051716 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYAL3 HYAL3 O43820 Hyaluronidase-3 chr3 GO:0051716 Not Cancer Driver No 48 0.115 10 0 0.0 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0051716 Not Cancer Driver No 61 0.115 251 28 0.112 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0051716 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0051716 Not Cancer Driver No 14 0.104 52 7 0.135 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0051716 Census, Compendium Yes 14 0.118 34 4 0.118 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0051716 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0051716 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0051716 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFIT1B IFIT1B Q5T764 Interferon-induced protein with tetratricopeptide repeats 1B chr10 GO:0051716 Not Cancer Driver No 59 0.124 21 1 0.048 0
IFIT2_ENST00000371826 IFIT2 P09913 Interferon-induced protein with tetratricopeptide repeats 2 chr10 GO:0051716 Not Cancer Driver No 73 0.155 85 17 0.2 0
IFIT3_ENST00000371811 IFIT3 O14879 Interferon-induced protein with tetratricopeptide repeats 3 chr10 GO:0051716 Not Cancer Driver No 47 0.096 143 11 0.077 0
IFITM2_ENST00000399817 IFITM2 Q01629 Interferon-induced transmembrane protein 2 chr11 GO:0051716 Not Cancer Driver No 23 0.174 17 5 0.294 0
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 GO:0051716 Compendium Yes 55 0.099 50 6 0.12 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0051716 Not Cancer Driver No 46 0.246 0 0 0.0 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0051716 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0051716 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0051716 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGFBPL1 IGFBPL1 Q8WX77 Insulin-like growth factor-binding protein-like 1 chr9 GO:0051716 Not Cancer Driver No 31 0.112 75 12 0.16 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0051716 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0051716 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0051716 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0051716 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0051716 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0051716 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0051716 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0051716 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 GO:0051716 Not Cancer Driver No 35 0.17 0 0 0.0 0
IL3RA IL3RA P26951 Interleukin-3 receptor subunit alpha chrX GO:0051716 Not Cancer Driver No 89 0.235 9 2 0.222 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0051716 Not Cancer Driver No 35 0.165 58 7 0.121 0
ILDR1_ENST00000344209 ILDR1 Q86SU0 Immunoglobulin-like domain-containing receptor 1 chr3 GO:0051716 Not Cancer Driver No 112 0.205 260 66 0.254 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0051716 Not Cancer Driver No 49 0.153 84 12 0.143 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 GO:0051716 Not Cancer Driver No 70 0.136 6 1 0.167 0
INA INA Q16352 Alpha-internexin chr10 GO:0051716 Not Cancer Driver No 62 0.124 256 43 0.168 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0051716 Not Cancer Driver No 31 0.124 108 15 0.139 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0051716 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0051716 Not Cancer Driver No 61 0.15 98 5 0.051 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0051716 Compendium Yes 173 0.111 682 76 0.111 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0051716 Not Cancer Driver No 42 0.094 34 2 0.059 7
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0051716 Not Cancer Driver No 37 0.134 43 1 0.023 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 GO:0051716 Not Cancer Driver No 47 0.209 11 3 0.273 0
INSRR INSRR P14616 Insulin receptor-related protein chr1 GO:0051716 Not Cancer Driver No 262 0.202 228 37 0.162 0
INTS7 INTS7 Q9NVH2 Integrator complex subunit 7 chr1 GO:0051716 Not Cancer Driver No 106 0.11 88 17 0.193 0
IP6K2 IP6K2 Q9UHH9 Inositol hexakisphosphate kinase 2 chr3 GO:0051716 Not Cancer Driver No 45 0.106 96 10 0.104 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0051716 Not Cancer Driver No 128 0.117 52 3 0.058 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0051716 Not Cancer Driver No 183 0.11 351 35 0.1 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0051716 Compendium Yes 49 0.151 228 31 0.136 2
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0051716 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0051716 Not Cancer Driver No 80 0.188 77 20 0.26 2
IRGC IRGC Q6NXR0 Interferon-inducible GTPase 5 chr19 GO:0051716 Not Cancer Driver No 98 0.212 158 36 0.228 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0051716 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0051716 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0051716 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0051716 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0051716 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0051716 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0051716 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0051716 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0051716 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0051716 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0051716 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0051716 Not Cancer Driver No 148 0.156 719 119 0.166 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0051716 Not Cancer Driver No 390 0.141 581 76 0.131 6
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 GO:0051716 Not Cancer Driver No 359 0.133 394 57 0.145 1
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0051716 Not Cancer Driver No 21 0.115 12 2 0.167 5
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0051716 Census, Compendium Yes 136 0.12 59 5 0.085 5
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0051716 Not Cancer Driver No 190 0.152 724 113 0.156 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0051716 Census Yes 35 0.106 281 25 0.089 0
JUNB JUNB P17275 Transcription factor JunB chr19 GO:0051716 Not Cancer Driver No 20 0.058 305 16 0.052 0
JUND JUND P17535 Transcription factor JunD chr19 GO:0051716 Not Cancer Driver No 21 0.061 313 19 0.061 0
JUP JUP P14923 Junction plakoglobin chr17 GO:0051716 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0051716 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0051716 Not Cancer Driver No 65 0.127 173 21 0.121 3
KAT6A_ENST00000406337 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 GO:0051716 Census, Compendium Yes 273 0.136 1420 193 0.136 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0051716 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0051716 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0051716 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0051716 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0051716 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNE2 KCNE2 Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 chr21 GO:0051716 Not Cancer Driver No 25 0.203 2 0 0.0 5
KCNH1 KCNH1 O95259 Potassium voltage-gated channel subfamily H member 1 chr1 GO:0051716 Not Cancer Driver No 247 0.25 248 70 0.282 10
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 GO:0051716 Not Cancer Driver No 189 0.163 466 50 0.107 117
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0051716 Not Cancer Driver No 103 0.241 49 11 0.224 12
KCNK18 KCNK18 Q7Z418 Potassium channel subfamily K member 18 chr10 GO:0051716 Not Cancer Driver No 103 0.268 7 0 0.0 0
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0051716 Not Cancer Driver No 54 0.137 60 7 0.117 6
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0051716 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0051716 Not Cancer Driver No 49 0.257 0 0 0.0 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0051716 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0051716 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0051716 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0051716 Not Cancer Driver No 78 0.149 215 33 0.153 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0051716 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:0051716 Not Cancer Driver No 189 0.115 1278 142 0.111 2
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0051716 Census, Compendium Yes 357 0.263 275 55 0.2 2
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0051716 Census, Compendium Yes 237 0.38 57 12 0.211 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 GO:0051716 Not Cancer Driver No 245 0.138 683 113 0.165 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0051716 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0051716 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0051716 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0051716 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0051716 Compendium Yes 77 0.168 366 40 0.109 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0051716 Not Cancer Driver No 34 0.139 154 24 0.156 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0051716 Not Cancer Driver No 90 0.142 50 8 0.16 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0051716 Not Cancer Driver No 77 0.158 0 0 0.0 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0051716 Census Yes 75 0.237 246 67 0.272 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:0051716 Not Cancer Driver No 44 0.101 21 2 0.095 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 GO:0051716 Not Cancer Driver No 13 0.081 96 7 0.073 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 GO:0051716 Not Cancer Driver No 12 0.096 0 0 0.0 0
LAMTOR3 LAMTOR3 Q9UHA4 Ragulator complex protein LAMTOR3 chr4 GO:0051716 Not Cancer Driver No 12 0.097 0 0 0.0 0
LAMTOR4 LAMTOR4 Q0VGL1 Ragulator complex protein LAMTOR4 chr7 GO:0051716 Not Cancer Driver No 8 0.081 4 0 0.0 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0051716 Not Cancer Driver No 10 0.11 17 0 0.0 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0051716 Not Cancer Driver No 133 0.113 97 10 0.103 1
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0051716 Not Cancer Driver No 84 0.175 6 0 0.0 0
LCE1D LCE1D Q5T752 Late cornified envelope protein 1D chr1 GO:0051716 Not Cancer Driver No 29 0.254 0 0 0.0 0
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0051716 Not Cancer Driver No 54 0.125 388 46 0.119 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0051716 Not Cancer Driver No 119 0.138 63 3 0.048 104
LDOC1 LDOC1 O95751 Protein LDOC1 chrX GO:0051716 Not Cancer Driver No 48 0.329 23 10 0.435 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0051716 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0051716 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0051716 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0051716 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0051716 Not Cancer Driver No 181 0.259 12 8 0.667 25
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0051716 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0051716 Not Cancer Driver No 134 0.147 63 10 0.159 2
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0051716 Not Cancer Driver No 37 0.177 86 12 0.14 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 GO:0051716 Census Yes 35 0.222 14 1 0.071 0
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:0051716 Compendium Yes 44 0.106 172 11 0.064 4
LPL LPL P06858 Lipoprotein lipase chr8 GO:0051716 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0051716 Not Cancer Driver No 54 0.235 2 0 0.0 1
LRCH1_ENST00000389798 LRCH1 Q9Y2L9 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 GO:0051716 Not Cancer Driver No 95 0.13 380 41 0.108 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0051716 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0051716 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0051716 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051716 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSP1_ENST00000311604 LSP1 P33241 Lymphocyte-specific protein 1 chr11 GO:0051716 Not Cancer Driver No 44 0.13 337 43 0.128 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 GO:0051716 Not Cancer Driver No 44 0.101 200 21 0.105 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0051716 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0051716 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0051716 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0051716 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0051716 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0051716 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 GO:0051716 Not Cancer Driver No 22 0.182 24 1 0.042 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 GO:0051716 Not Cancer Driver No 10 0.08 17 1 0.059 0
MAP1LC3B2 MAP1LC3B2 A6NCE7 Microtubule-associated proteins 1A/1B light chain 3 beta 2 chr12 GO:0051716 Not Cancer Driver No 19 0.152 17 7 0.412 0
MAP1LC3C MAP1LC3C Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C chr1 GO:0051716 Not Cancer Driver No 32 0.218 31 5 0.161 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0051716 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0051716 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0051716 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0051716 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0051716 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0051716 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K1 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 GO:0051716 Census, Compendium Yes 184 0.122 820 62 0.076 3
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 GO:0051716 Not Cancer Driver No 94 0.099 543 52 0.096 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0051716 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 GO:0051716 Not Cancer Driver No 75 0.121 313 47 0.15 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0051716 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0051716 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0051716 Not Cancer Driver No 116 0.139 276 41 0.149 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 GO:0051716 Not Cancer Driver No 88 0.19 107 16 0.15 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0051716 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0051716 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0051716 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0051716 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0051716 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0051716 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0051716 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP3_ENST00000250894 MAPK8IP3 Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 chr16 GO:0051716 Not Cancer Driver No 179 0.134 746 110 0.147 3
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0051716 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0051716 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0051716 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0051716 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0051716 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0051716 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 GO:0051716 Not Cancer Driver No 36 0.091 31 4 0.129 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0051716 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 GO:0051716 Not Cancer Driver No 140 0.133 206 36 0.175 1
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0051716 Not Cancer Driver No 63 0.121 16 4 0.25 9
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0051716 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0051716 Not Cancer Driver No 218 0.236 124 33 0.266 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0051716 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0051716 Not Cancer Driver No 101 0.14 128 22 0.172 0
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0051716 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0051716 Not Cancer Driver No 56 0.049 523 13 0.025 0
MCOLN1 MCOLN1 Q9GZU1 Mucolipin-1 chr19 GO:0051716 Not Cancer Driver No 77 0.133 63 15 0.238 7
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0051716 Census, Compendium Yes 56 0.114 297 37 0.125 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 GO:0051716 Census, Compendium Yes 57 0.116 202 26 0.129 1
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0051716 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 GO:0051716 Not Cancer Driver No 62 0.122 454 56 0.123 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0051716 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEN1 MEN1 O00255 Menin chr11 GO:0051716 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0051716 Not Cancer Driver No 54 0.205 47 13 0.277 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0051716 Not Cancer Driver No 74 0.128 274 29 0.106 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0051716 Not Cancer Driver No 35 0.137 0 0 0.0 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0051716 Not Cancer Driver No 80 0.106 81 9 0.111 20
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0051716 Not Cancer Driver No 25 0.104 207 22 0.106 0
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0051716 Not Cancer Driver No 33 0.096 95 7 0.074 1
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 GO:0051716 Not Cancer Driver No 26 0.168 0 0 0.0 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 GO:0051716 Not Cancer Driver No 222 0.116 1490 178 0.119 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0051716 Not Cancer Driver No 4 0.035 0 0 0.0 0
MKNK2_ENST00000591601 MKNK2 Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 chr19 GO:0051716 Not Cancer Driver No 42 0.09 124 8 0.065 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 GO:0051716 Not Cancer Driver No 53 0.141 35 7 0.2 15
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0051716 Not Cancer Driver No 189 0.252 40 17 0.425 4
MMP1 MMP1 P03956 Interstitial collagenase chr11 GO:0051716 Not Cancer Driver No 83 0.177 113 18 0.159 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0051716 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP3 MMP3 P08254 Stromelysin-1 chr11 GO:0051716 Not Cancer Driver No 99 0.208 66 14 0.212 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0051716 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0051716 Not Cancer Driver No 180 0.442 172 76 0.442 0
MPV17 MPV17 P39210 Protein Mpv17 chr2 GO:0051716 Not Cancer Driver No 21 0.119 0 0 0.0 16
MRAS_ENST00000423968 MRAS O14807 Ras-related protein M-Ras chr3 GO:0051716 Not Cancer Driver No 27 0.13 50 13 0.26 3
MRC1 MRC1 P22897 Macrophage mannose receptor 1 chr10 GO:0051716 Not Cancer Driver No 40 0.027 126 1 0.008 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0051716 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRPL15 MRPL15 Q9P015 39S ribosomal protein L15, mitochondrial chr8 GO:0051716 Not Cancer Driver No 32 0.108 81 3 0.037 0
MSC MSC O60682 Musculin chr8 GO:0051716 Not Cancer Driver No 47 0.228 173 41 0.237 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0051716 Census Yes 154 0.113 386 41 0.106 6
MSN MSN P26038 Moesin chrX GO:0051716 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0051716 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0051716 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT1A MT1A P04731 Metallothionein-1A chr16 GO:0051716 Not Cancer Driver No 8 0.131 0 0 0.0 0
MT1B MT1B P07438 Metallothionein-1B chr16 GO:0051716 Not Cancer Driver No 7 0.115 0 0 0.0 0
MT1E MT1E P04732 Metallothionein-1E chr16 GO:0051716 Not Cancer Driver No 4 0.066 0 0 0.0 0
MT1F MT1F P04733 Metallothionein-1F chr16 GO:0051716 Not Cancer Driver No 3 0.049 0 0 0.0 0
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0051716 Not Cancer Driver No 9 0.145 0 0 0.0 0
MT1H MT1H P80294 Metallothionein-1H chr16 GO:0051716 Not Cancer Driver No 18 0.295 0 0 0.0 0
MT1HL1 MT1HL1 P0DM35 Metallothionein 1H-like protein 1 chr1 GO:0051716 Not Cancer Driver No 16 0.262 0 0 0.0 0
MT1M MT1M Q8N339 Metallothionein-1M chr16 GO:0051716 Not Cancer Driver No 11 0.18 0 0 0.0 0
MT1X MT1X P80297 Metallothionein-1X chr16 GO:0051716 Not Cancer Driver No 3 0.049 0 0 0.0 0
MT2A MT2A P02795 Metallothionein-2 chr16 GO:0051716 Not Cancer Driver No 8 0.131 0 0 0.0 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0051716 Not Cancer Driver No 7 0.103 0 0 0.0 0
MT4 MT4 P47944 Metallothionein-4 chr16 GO:0051716 Not Cancer Driver No 11 0.177 0 0 0.0 0
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 GO:0051716 Not Cancer Driver No 115 0.153 553 76 0.137 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 GO:0051716 Not Cancer Driver No 70 0.118 225 28 0.124 0
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0051716 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0051716 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPN MTPN P58546 Myotrophin chr7 GO:0051716 Not Cancer Driver No 11 0.093 11 3 0.273 0
MTR MTR Q99707 Methionine synthase chr1 GO:0051716 Not Cancer Driver No 151 0.119 104 17 0.163 2
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0051716 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0051716 Not Cancer Driver No 62 0.083 582 49 0.084 0
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0051716 Not Cancer Driver No 107 0.142 584 86 0.147 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0051716 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0051716 Not Cancer Driver No 48 0.136 16 2 0.125 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:0051716 Not Cancer Driver No 67 0.122 232 38 0.164 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0051716 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 GO:0051716 Not Cancer Driver No 111 0.159 506 85 0.168 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0051716 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0051716 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0051716 Not Cancer Driver No 343 0.179 957 184 0.192 3
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0051716 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYNN_ENST00000356716 MYNN Q9NPC7 Myoneurin chr3 GO:0051716 Not Cancer Driver No 76 0.125 214 24 0.112 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0051716 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0051716 Not Cancer Driver No 176 0.136 342 41 0.12 3
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0051716 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0051716 Not Cancer Driver No 36 0.161 132 20 0.152 0
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:0051716 Not Cancer Driver No 49 0.164 223 39 0.175 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:0051716 Not Cancer Driver No 50 0.189 197 38 0.193 2
N4BP1 N4BP1 O75113 NEDD4-binding protein 1 chr16 GO:0051716 Not Cancer Driver No 108 0.121 432 58 0.134 0
NBN NBN O60934 Nibrin chr8 GO:0051716 Census Yes 90 0.119 417 54 0.129 1
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0051716 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0051716 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0051716 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCL NCL P19338 Nucleolin chr2 GO:0051716 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0051716 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0051716 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0051716 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0051716 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0051716 Not Cancer Driver No 125 0.22 129 29 0.225 1
NDOR1_ENST00000344894 NDOR1 Q9UHB4 NADPH-dependent diflavin oxidoreductase 1 chr9 GO:0051716 Not Cancer Driver No 60 0.101 67 7 0.104 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0051716 Census Yes 66 0.168 140 22 0.157 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0051716 Not Cancer Driver No 29 0.201 24 4 0.167 1
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 GO:0051716 Not Cancer Driver No 58 0.125 49 5 0.102 4
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0051716 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEFH NEFH P12036 Neurofilament heavy polypeptide chr22 GO:0051716 Compendium Yes 114 0.111 871 106 0.122 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0051716 Not Cancer Driver No 92 0.169 285 39 0.137 12
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0051716 Not Cancer Driver No 35 0.116 23 0 0.0 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0051716 Not Cancer Driver No 60 0.101 294 37 0.126 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0051716 Not Cancer Driver No 62 0.108 153 11 0.072 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0051716 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0051716 Not Cancer Driver No 26 0.068 210 14 0.067 2
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0051716 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0051716 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 GO:0051716 Not Cancer Driver No 57 0.123 333 41 0.123 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0051716 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0051716 Compendium Yes 37 0.117 102 9 0.088 1
NFYB NFYB P25208 Nuclear transcription factor Y subunit beta chr12 GO:0051716 Not Cancer Driver No 23 0.111 94 7 0.074 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0051716 Not Cancer Driver No 57 0.133 172 25 0.145 0
NGLY1 NGLY1 Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase chr3 GO:0051716 Not Cancer Driver No 79 0.121 98 13 0.133 0
NIM1K NIM1K Q8IY84 Serine/threonine-protein kinase NIM1 chr5 GO:0051716 Not Cancer Driver No 73 0.167 126 21 0.167 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0051716 Compendium Yes 353 0.126 1528 184 0.12 37
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0051716 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0051716 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0051716 Not Cancer Driver No 300 0.306 71 20 0.282 9
NME8_ENST00000440017 NME8 Q8N427 Thioredoxin domain-containing protein 3 chr7 GO:0051716 Not Cancer Driver No 178 0.303 87 44 0.506 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 GO:0051716 Not Cancer Driver No 77 0.103 281 31 0.11 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0051716 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0051716 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0051716 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0051716 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0051716 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0051716 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0051716 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0051716 Not Cancer Driver No 229 0.286 429 114 0.266 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 GO:0051716 Not Cancer Driver No 155 0.121 24 0 0.0 150
NPC1L1 NPC1L1 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 chr7 GO:0051716 Not Cancer Driver No 222 0.163 8 2 0.25 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0051716 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0051716 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0051716 Not Cancer Driver No 63 0.146 185 24 0.13 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0051716 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0051716 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0051716 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0051716 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0051716 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0051716 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0051716 Census Yes 83 0.133 298 37 0.124 0
NR5A2 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 GO:0051716 Not Cancer Driver No 126 0.233 154 35 0.227 0
NREP_ENST00000447165 NREP Q16612 Neuronal regeneration-related protein chr5 GO:0051716 Not Cancer Driver No 17 0.25 36 13 0.361 0
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 GO:0051716 Not Cancer Driver No 141 0.122 998 124 0.124 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0051716 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0051716 Not Cancer Driver No 161 0.173 207 45 0.217 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0051716 Not Cancer Driver No 30 0.121 119 12 0.101 0
NSMCE3 NSMCE3 Q96MG7 Non-structural maintenance of chromosomes element 3 homolog chr15 GO:0051716 Not Cancer Driver No 33 0.109 128 7 0.055 2
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0051716 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0051716 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0051716 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0051716 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0051716 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0051716 Not Cancer Driver No 30 0.123 243 30 0.123 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0051716 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0051716 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUP35 NUP35 Q8NFH5 Nucleoporin NUP35 chr2 GO:0051716 Not Cancer Driver No 39 0.12 209 27 0.129 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0051716 Not Cancer Driver No 67 0.168 71 12 0.169 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0051716 Not Cancer Driver No 22 0.039 52 6 0.115 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0051716 Not Cancer Driver No 37 0.107 71 12 0.169 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 GO:0051716 Not Cancer Driver No 52 0.099 34 4 0.118 0
OMG OMG P23515 Oligodendrocyte-myelin glycoprotein chr17 GO:0051716 Not Cancer Driver No 38 0.086 122 10 0.082 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0051716 Not Cancer Driver No 114 0.119 131 17 0.13 60
OPN1SW OPN1SW P03999 Short-wave-sensitive opsin 1 chr7 GO:0051716 Not Cancer Driver No 65 0.187 20 1 0.05 4
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0051716 Not Cancer Driver No 39 0.097 6 1 0.167 0
OPN5 OPN5 Q6U736 Opsin-5 chr6 GO:0051716 Not Cancer Driver No 65 0.184 0 0 0.0 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0051716 Not Cancer Driver No 91 0.245 30 3 0.1 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0051716 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0051716 Not Cancer Driver No 107 0.268 58 27 0.466 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0051716 Not Cancer Driver No 58 0.101 470 51 0.109 6
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0051716 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSBPL7_ENST00000392507 OSBPL7 Q9BZF2 Oxysterol-binding protein-related protein 7 chr17 GO:0051716 Not Cancer Driver No 99 0.118 395 44 0.111 0
OSER1 OSER1 Q9NX31 Oxidative stress-responsive serine-rich protein 1 chr20 GO:0051716 Not Cancer Driver No 32 0.11 221 28 0.127 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0051716 Not Cancer Driver No 57 0.214 67 17 0.254 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0051716 Not Cancer Driver No 126 0.144 544 76 0.14 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0051716 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0051716 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0051716 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0051716 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0051716 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY11 P2RY11 Q96G91 P2Y purinoceptor 11 chr19 GO:0051716 Not Cancer Driver No 47 0.126 31 1 0.032 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0051716 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 GO:0051716 Not Cancer Driver No 67 0.178 60 13 0.217 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0051716 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0051716 Not Cancer Driver No 50 0.152 10 5 0.5 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0051716 Not Cancer Driver No 61 0.12 79 15 0.19 1
PADI2 PADI2 Q9Y2J8 Protein-arginine deiminase type-2 chr1 GO:0051716 Not Cancer Driver No 121 0.182 60 18 0.3 0
PALM PALM O75781 Paralemmin-1 chr19 GO:0051716 Not Cancer Driver No 50 0.129 381 50 0.131 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0051716 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0051716 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0051716 Not Cancer Driver No 37 0.115 33 3 0.091 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0051716 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0051716 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0051716 Census Yes 84 0.187 291 55 0.189 4
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0051716 Not Cancer Driver No 120 0.112 461 39 0.085 0
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0051716 Not Cancer Driver No 23 0.071 92 6 0.065 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0051716 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0051716 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0051716 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCOLCE2 PCOLCE2 Q9UKZ9 Procollagen C-endopeptidase enhancer 2 chr3 GO:0051716 Not Cancer Driver No 102 0.246 25 3 0.12 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0051716 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0051716 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0051716 Not Cancer Driver No 114 0.213 132 30 0.227 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0051716 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0051716 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0051716 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0051716 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0051716 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0051716 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0051716 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0051716 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0051716 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0051716 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 GO:0051716 Not Cancer Driver No 57 0.113 98 11 0.112 0
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0051716 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0051716 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0051716 Not Cancer Driver No 70 0.17 14 2 0.143 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0051716 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0051716 Not Cancer Driver No 14 0.047 38 4 0.105 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 GO:0051716 Not Cancer Driver No 134 0.119 610 82 0.134 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0051716 Not Cancer Driver No 109 0.408 142 62 0.437 0
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:0051716 Not Cancer Driver No 133 0.17 43 10 0.233 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0051716 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0051716 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0051716 Not Cancer Driver No 144 0.192 56 7 0.125 30
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0051716 Not Cancer Driver No 50 0.12 49 3 0.061 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0051716 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0051716 Not Cancer Driver No 93 0.102 137 14 0.102 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0051716 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIEZO2 PIEZO2 Q9H5I5 Piezo-type mechanosensitive ion channel component 2 chr18 GO:0051716 Not Cancer Driver No 198 0.072 603 19 0.032 8
PIGA PIGA P37287 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A chrX GO:0051716 Not Cancer Driver No 51 0.105 21 0 0.0 13
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0051716 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0051716 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0051716 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0051716 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0051716 Not Cancer Driver No 193 0.142 315 45 0.143 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0051716 Not Cancer Driver No 57 0.098 99 13 0.131 23
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0051716 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKD1L3 PKD1L3 Q7Z443 Polycystic kidney disease protein 1-like 3 chr16 GO:0051716 Not Cancer Driver No 97 0.056 145 9 0.062 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0051716 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKD2L1 PKD2L1 Q9P0L9 Polycystic kidney disease 2-like 1 protein chr10 GO:0051716 Not Cancer Driver No 135 0.168 180 32 0.178 0
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0051716 Not Cancer Driver No 112 0.195 26 5 0.192 101
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0051716 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0051716 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0051716 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0051716 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0051716 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0051716 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0051716 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0051716 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEC PLEC Q15149 Plectin chr8 GO:0051716 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0051716 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLIN1_ENST00000430628 PLIN1 O60240 Perilipin-1 chr15 GO:0051716 Not Cancer Driver No 43 0.082 304 20 0.066 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0051716 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0051716 Not Cancer Driver No 75 0.116 202 15 0.074 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0051716 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0051716 Census, Compendium Yes 112 0.127 312 34 0.109 0
PMM1 PMM1 Q92871 Phosphomannomutase 1 chr22 GO:0051716 Not Cancer Driver No 37 0.141 15 0 0.0 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0051716 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0051716 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLB POLB P06746 DNA polymerase beta chr8 GO:0051716 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0051716 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:0051716 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:0051716 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0051716 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0051716 Census, Compendium Yes 409 0.179 239 44 0.184 3
POLE2 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0051716 Not Cancer Driver No 53 0.101 32 2 0.062 0
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0051716 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLI POLI Q9UNA4 DNA polymerase iota chr18 GO:0051716 Not Cancer Driver No 82 0.111 300 32 0.107 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0051716 Not Cancer Driver No 97 0.111 293 36 0.123 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0051716 Census, Compendium Yes 364 0.141 949 135 0.142 0
POLR2D POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 GO:0051716 Not Cancer Driver No 13 0.092 54 2 0.037 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 GO:0051716 Not Cancer Driver No 21 0.168 22 5 0.227 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0051716 Not Cancer Driver No 62 0.092 93 4 0.043 9
POSTN POSTN Q15063 Periostin chr13 GO:0051716 Not Cancer Driver No 204 0.244 86 27 0.314 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0051716 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0051716 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0051716 Census Yes 72 0.143 44 4 0.091 3
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0051716 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPID PPID Q08752 Peptidyl-prolyl cis-trans isomerase D chr4 GO:0051716 Not Cancer Driver No 36 0.097 94 9 0.096 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0051716 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0051716 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 GO:0051716 Not Cancer Driver No 114 0.151 384 53 0.138 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0051716 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0051716 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0051716 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0051716 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0051716 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0051716 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0051716 Compendium Yes 85 0.163 140 27 0.193 7
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0051716 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0051716 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRDM5 PRDM5 Q9NQX1 PR domain zinc finger protein 5 chr4 GO:0051716 Not Cancer Driver No 135 0.214 148 41 0.277 1
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0051716 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0051716 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0051716 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0051716 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0051716 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0051716 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0051716 Census Yes 53 0.151 24 0 0.0 2
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0051716 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0051716 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:0051716 Not Cancer Driver No 74 0.151 144 25 0.174 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0051716 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0051716 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0051716 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0051716 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0051716 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0051716 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0051716 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 GO:0051716 Not Cancer Driver No 43 0.115 71 7 0.099 0
PRNP PRNP P04156 Major prion protein chr20 GO:0051716 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0051716 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0051716 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0051716 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0051716 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0051716 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0051716 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0051716 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0051716 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0051716 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0051716 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0051716 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0051716 Census Yes 42 0.093 12 0 0.0 0
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0051716 Not Cancer Driver No 153 0.143 359 58 0.162 0
PTN PTN P21246 Pleiotrophin chr7 GO:0051716 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 GO:0051716 Not Cancer Driver No 30 0.173 3 0 0.0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0051716 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0051716 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0051716 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0051716 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 GO:0051716 Not Cancer Driver No 268 0.141 696 96 0.138 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0051716 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0051716 Census, Compendium Yes 535 0.371 299 125 0.418 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0051716 Not Cancer Driver No 62 0.105 341 24 0.07 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0051716 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0051716 Not Cancer Driver No 174 0.354 291 99 0.34 0
QRICH1_ENST00000357496 QRICH1 Q2TAL8 Transcriptional regulator QRICH1 chr3 GO:0051716 Not Cancer Driver No 93 0.12 423 55 0.13 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0051716 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0051716 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB20 RAB20 Q9NX57 Ras-related protein Rab-20 chr13 GO:0051716 Not Cancer Driver No 33 0.141 57 8 0.14 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 GO:0051716 Not Cancer Driver No 25 0.124 25 2 0.08 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0051716 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB43_ENST00000393305 RAB43 Q86YS6 Ras-related protein Rab-43 chr3 GO:0051716 Not Cancer Driver No 26 0.123 14 0 0.0 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0051716 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0051716 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0051716 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:0051716 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD23B RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 GO:0051716 Not Cancer Driver No 54 0.132 324 41 0.127 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0051716 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0051716 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0051716 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0051716 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0051716 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAD9B RAD9B Q6WBX8 Cell cycle checkpoint control protein RAD9B chr12 GO:0051716 Not Cancer Driver No 46 0.108 40 6 0.15 0
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0051716 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0051716 Not Cancer Driver No 18 0.103 34 6 0.176 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0051716 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0051716 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0051716 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0051716 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0051716 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0051716 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0051716 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0051716 Not Cancer Driver No 158 0.147 589 87 0.148 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0051716 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0051716 Not Cancer Driver No 97 0.105 197 19 0.096 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0051716 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0051716 Not Cancer Driver No 82 0.181 164 24 0.146 0
RASA4 RASA4 O43374 Ras GTPase-activating protein 4 chr7 GO:0051716 Not Cancer Driver No 14 0.017 164 3 0.018 0
RASA4B_ENST00000465829 RASA4B C9J798 Ras GTPase-activating protein 4B chr7 GO:0051716 Not Cancer Driver No 13 0.016 157 1 0.006 0
RASAL1_ENST00000261729 RASAL1 O95294 RasGAP-activating-like protein 1 chr12 GO:0051716 Not Cancer Driver No 132 0.164 106 25 0.236 0
RASGRP2_ENST00000377497 RASGRP2 Q7LDG7 RAS guanyl-releasing protein 2 chr11 GO:0051716 Not Cancer Driver No 98 0.161 88 15 0.17 4
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0051716 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX GO:0051716 Not Cancer Driver No 67 0.158 138 19 0.138 0
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 GO:0051716 Not Cancer Driver No 51 0.121 214 29 0.136 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0051716 Not Cancer Driver No 82 0.21 380 81 0.213 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0051716 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0051716 Not Cancer Driver No 158 0.139 796 115 0.144 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0051716 Not Cancer Driver No 33 0.126 23 0 0.0 0
RCSD1 RCSD1 Q6JBY9 CapZ-interacting protein chr1 GO:0051716 Not Cancer Driver No 70 0.168 416 70 0.168 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0051716 Not Cancer Driver No 71 0.122 297 37 0.125 1
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0051716 Not Cancer Driver No 60 0.11 244 26 0.107 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0051716 Not Cancer Driver No 132 0.133 495 71 0.143 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0051716 Compendium Yes 75 0.136 400 48 0.12 0
REN REN P00797 Renin chr1 GO:0051716 Not Cancer Driver No 60 0.148 10 0 0.0 3
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0051716 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0051716 Census, Compendium Yes 208 0.187 105 12 0.114 139
REV1 REV1 Q9UBZ9 DNA repair protein REV1 chr2 GO:0051716 Not Cancer Driver No 122 0.098 660 67 0.102 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:0051716 Not Cancer Driver No 379 0.121 1665 211 0.127 0
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:0051716 Census Yes 68 0.088 318 30 0.094 1
RFX2_ENST00000359161 RFX2 P48378 DNA-binding protein RFX2 chr19 GO:0051716 Not Cancer Driver No 79 0.109 301 30 0.1 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0051716 Not Cancer Driver No 57 0.101 309 37 0.12 0
RGS9 RGS9 O75916 Regulator of G-protein signaling 9 chr17 GO:0051716 Not Cancer Driver No 138 0.205 240 65 0.271 1
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0051716 Not Cancer Driver No 38 0.121 69 9 0.13 0
RHEX RHEX Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein chr1 GO:0051716 Not Cancer Driver No 35 0.203 116 27 0.233 0
RHNO1 RHNO1 Q9BSD3 RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 chr12 GO:0051716 Not Cancer Driver No 26 0.109 193 21 0.109 0
RHO RHO P08100 Rhodopsin chr3 GO:0051716 Not Cancer Driver No 68 0.195 18 3 0.167 69
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0051716 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0051716 Not Cancer Driver No 52 0.265 19 2 0.105 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0051716 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0051716 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0051716 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0051716 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0051716 Not Cancer Driver No 66 0.127 295 39 0.132 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0051716 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0051716 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0051716 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 GO:0051716 Not Cancer Driver No 41 0.102 102 10 0.098 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0051716 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0051716 Not Cancer Driver No 27 0.119 11 3 0.273 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0051716 Not Cancer Driver No 30 0.081 112 7 0.062 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0051716 Not Cancer Driver No 17 0.094 69 3 0.043 0
RNMT_ENST00000543302 RNMT O43148 mRNA cap guanine-N7 methyltransferase chr18 GO:0051716 Not Cancer Driver No 67 0.141 159 23 0.145 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0051716 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROMO1_ENST00000397416 ROMO1 P60602 Reactive oxygen species modulator 1 chr20 GO:0051716 Not Cancer Driver No 9 0.114 0 0 0.0 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0051716 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 GO:0051716 Not Cancer Driver No 107 0.228 87 22 0.253 1
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0051716 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0051716 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0051716 Not Cancer Driver No 109 0.205 10 1 0.1 44
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 GO:0051716 Not Cancer Driver No 27 0.133 33 2 0.061 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0051716 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0051716 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 GO:0051716 Not Cancer Driver No 34 0.084 79 3 0.038 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 GO:0051716 Not Cancer Driver No 16 0.11 14 1 0.071 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 GO:0051716 Not Cancer Driver No 4 0.048 22 2 0.091 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0051716 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0051716 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0051716 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0051716 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0051716 Not Cancer Driver No 180 0.242 136 36 0.265 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0051716 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0051716 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0051716 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0051716 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 GO:0051716 Compendium Yes 29 0.073 61 1 0.016 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0051716 Not Cancer Driver No 42 0.105 83 5 0.06 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0051716 Not Cancer Driver No 66 0.145 270 44 0.163 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0051716 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTF2_ENST00000357348 RTF2 Q9BY42 Replication termination factor 2 chr20 GO:0051716 Not Cancer Driver No 44 0.144 170 22 0.129 0
RTN4RL1 RTN4RL1 Q86UN2 Reticulon-4 receptor-like 1 chr17 GO:0051716 Not Cancer Driver No 56 0.127 142 12 0.085 0
RTN4RL2 RTN4RL2 Q86UN3 Reticulon-4 receptor-like 2 chr11 GO:0051716 Not Cancer Driver No 38 0.09 121 5 0.041 0
RUFY4_ENST00000344321 RUFY4 Q6ZNE9 RUN and FYVE domain-containing protein 4 chr2 GO:0051716 Not Cancer Driver No 77 0.135 307 51 0.166 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0051716 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:0051716 Not Cancer Driver No 28 0.115 168 19 0.113 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0051716 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0051716 Not Cancer Driver No 1703 0.343 782 281 0.359 51
RYR3 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0051716 Not Cancer Driver No 1079 0.222 649 162 0.25 0
SAG SAG P10523 S-arrestin chr2 GO:0051716 Not Cancer Driver No 70 0.173 102 11 0.108 0
SAXO1 SAXO1 Q8IYX7 Stabilizer of axonemal microtubules 1 chr9 GO:0051716 Not Cancer Driver No 63 0.133 249 35 0.141 0
SBNO2 SBNO2 Q9Y2G9 Protein strawberry notch homolog 2 chr19 GO:0051716 Not Cancer Driver No 108 0.079 456 29 0.064 0
SCAP SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 GO:0051716 Not Cancer Driver No 145 0.113 329 36 0.109 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0051716 Not Cancer Driver No 10 0.069 73 9 0.123 0
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0051716 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0051716 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0051716 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0051716 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0051716 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0051716 Not Cancer Driver No 129 0.199 57 11 0.193 0
SDE2 SDE2 Q6IQ49 Replication stress response regulator SDE2 chr1 GO:0051716 Not Cancer Driver No 56 0.124 290 35 0.121 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 GO:0051716 Not Cancer Driver No 16 0.072 130 9 0.069 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0051716 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0051716 Not Cancer Driver No 7 0.037 122 6 0.049 0
SELPLG_ENST00000550948 SELPLG Q14242 P-selectin glycoprotein ligand 1 chr12 GO:0051716 Not Cancer Driver No 68 0.165 297 48 0.162 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0051716 Not Cancer Driver No 136 0.132 456 72 0.158 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0051716 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0051716 Not Cancer Driver No 51 0.122 57 5 0.088 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0051716 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0051716 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0051716 Not Cancer Driver No 84 0.171 44 4 0.091 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0051716 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFR1 SFR1 Q86XK3 Swi5-dependent recombination DNA repair protein 1 homolog chr10 GO:0051716 Not Cancer Driver No 21 0.086 109 12 0.11 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0051716 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0051716 Not Cancer Driver No 47 0.159 1 0 0.0 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0051716 Census, Compendium Yes 58 0.135 86 16 0.186 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0051716 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0051716 Not Cancer Driver No 143 0.148 241 43 0.178 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0051716 Not Cancer Driver No 76 0.216 214 50 0.234 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0051716 Not Cancer Driver No 41 0.112 82 10 0.122 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0051716 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0051716 Not Cancer Driver No 51 0.106 32 7 0.219 0
SHPK SHPK Q9UHJ6 Sedoheptulokinase chr17 GO:0051716 Not Cancer Driver No 44 0.092 31 1 0.032 0
SHROOM2 SHROOM2 Q13796 Protein Shroom2 chrX GO:0051716 Not Cancer Driver No 215 0.133 1381 188 0.136 0
SHROOM3 SHROOM3 Q8TF72 Protein Shroom3 chr4 GO:0051716 Not Cancer Driver No 253 0.127 1756 220 0.125 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0051716 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 GO:0051716 Not Cancer Driver No 94 0.102 525 56 0.107 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0051716 Compendium Yes 172 0.135 617 73 0.118 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0051716 Not Cancer Driver No 67 0.064 666 43 0.065 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0051716 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0051716 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0051716 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0051716 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC10A1 SLC10A1 Q14973 Sodium/bile acid cotransporter chr14 GO:0051716 Not Cancer Driver No 39 0.112 0 0 0.0 4
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0051716 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 GO:0051716 Not Cancer Driver No 168 0.146 280 46 0.164 0
SLC13A5 SLC13A5 Q86YT5 Solute carrier family 13 member 5 chr17 GO:0051716 Not Cancer Driver No 75 0.132 5 0 0.0 6
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0051716 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0051716 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0051716 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC23A2 SLC23A2 Q9UGH3 Solute carrier family 23 member 2 chr20 GO:0051716 Not Cancer Driver No 87 0.134 76 8 0.105 0
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0051716 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0051716 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A23 SLC25A23 Q9BV35 Calcium-binding mitochondrial carrier protein SCaMC-3 chr19 GO:0051716 Not Cancer Driver No 63 0.135 74 8 0.108 0
SLC25A24 SLC25A24 Q6NUK1 Calcium-binding mitochondrial carrier protein SCaMC-1 chr1 GO:0051716 Not Cancer Driver No 40 0.084 21 2 0.095 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0051716 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0051716 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0051716 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0051716 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0051716 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0051716 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC2A5 SLC2A5 P22732 Solute carrier family 2, facilitated glucose transporter member 5 chr1 GO:0051716 Not Cancer Driver No 73 0.146 12 4 0.333 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0051716 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0051716 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 GO:0051716 Not Cancer Driver No 60 0.119 9 1 0.111 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0051716 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC38A9 SLC38A9 Q8NBW4 Sodium-coupled neutral amino acid transporter 9 chr5 GO:0051716 Not Cancer Driver No 57 0.102 33 2 0.061 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0051716 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 GO:0051716 Not Cancer Driver No 77 0.119 116 11 0.095 9
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0051716 Not Cancer Driver No 67 0.124 139 18 0.129 1
SLC41A1 SLC41A1 Q8IVJ1 Solute carrier family 41 member 1 chr1 GO:0051716 Not Cancer Driver No 68 0.133 103 15 0.146 1
SLC4A11_ENST00000539553 SLC4A11 Q8NBS3 Solute carrier family 4 member 11 chr20 GO:0051716 Not Cancer Driver No 159 0.182 69 10 0.145 42
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0051716 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0051716 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0051716 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0051716 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLFN14 SLFN14 P0C7P3 Protein SLFN14 chr17 GO:0051716 Not Cancer Driver No 66 0.072 61 3 0.049 4
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0051716 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0051716 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0051716 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0051716 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0051716 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 GO:0051716 Census, Compendium Yes 48 0.093 216 18 0.083 2
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0051716 Census, Compendium Yes 200 0.162 717 114 0.159 21
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0051716 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0051716 Not Cancer Driver No 128 0.117 458 57 0.124 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0051716 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0051716 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0051716 Not Cancer Driver No 92 0.14 224 29 0.129 0
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0051716 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0051716 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0051716 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0051716 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX10_ENST00000396376 SNX10 Q9Y5X0 Sorting nexin-10 chr7 GO:0051716 Not Cancer Driver No 24 0.119 52 8 0.154 4
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0051716 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0051716 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0051716 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0051716 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0051716 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0051716 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOST SOST Q9BQB4 Sclerostin chr17 GO:0051716 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOX1 SOX1 O00570 Transcription factor SOX-1 chr13 GO:0051716 Not Cancer Driver No 26 0.066 304 25 0.082 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0051716 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0051716 Compendium Yes 81 0.196 378 59 0.156 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0051716 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0051716 Compendium Yes 86 0.169 495 82 0.166 18
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0051716 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0051716 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0051716 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0051716 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0051716 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0051716 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPOCK2_ENST00000317376 SPOCK2 Q92563 Testican-2 chr10 GO:0051716 Not Cancer Driver No 48 0.113 113 8 0.071 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0051716 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0051716 Not Cancer Driver No 73 0.149 252 38 0.151 1
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0051716 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0051716 Not Cancer Driver No 34 0.114 134 20 0.149 7
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0051716 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0051716 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0051716 Not Cancer Driver No 35 0.135 0 0 0.0 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0051716 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0051716 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0051716 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRM SRM P19623 Spermidine synthase chr1 GO:0051716 Not Cancer Driver No 27 0.089 23 0 0.0 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 GO:0051716 Census Yes 31 0.189 125 27 0.216 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 GO:0051716 Not Cancer Driver No 40 0.168 175 26 0.149 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0051716 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0051716 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0051716 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0051716 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0051716 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0051716 Not Cancer Driver No 60 0.165 45 12 0.267 0
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0051716 Not Cancer Driver No 17 0.215 0 0 0.0 0
ST3GAL6_ENST00000394162 ST3GAL6 Q9Y274 Type 2 lactosamine alpha-2,3-sialyltransferase chr3 GO:0051716 Not Cancer Driver No 52 0.157 0 0 0.0 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0051716 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0051716 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0051716 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0051716 Census, Compendium Yes 106 0.125 325 44 0.135 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0051716 Not Cancer Driver No 59 0.239 58 12 0.207 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 GO:0051716 Not Cancer Driver No 74 0.136 270 39 0.144 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0051716 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0051716 Not Cancer Driver No 64 0.117 182 19 0.104 0
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0051716 Not Cancer Driver No 34 0.19 122 23 0.189 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0051716 Not Cancer Driver No 40 0.112 117 9 0.077 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0051716 Not Cancer Driver No 121 0.122 659 83 0.126 2
STRA8 STRA8 Q7Z7C7 Stimulated by retinoic acid gene 8 protein homolog chr7 GO:0051716 Not Cancer Driver No 45 0.136 105 15 0.143 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0051716 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 GO:0051716 Not Cancer Driver No 32 0.136 98 10 0.102 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0051716 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0051716 Not Cancer Driver No 59 0.1 64 9 0.141 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0051716 Not Cancer Driver No 78 0.141 211 24 0.114 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0051716 Not Cancer Driver No 10 0.099 76 7 0.092 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0051716 Not Cancer Driver No 59 0.143 15 1 0.067 0
SWI5 SWI5 Q1ZZU3 DNA repair protein SWI5 homolog chr9 GO:0051716 Not Cancer Driver No 45 0.191 128 35 0.273 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0051716 Not Cancer Driver No 31 0.088 221 22 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0051716 Census Yes 96 0.151 131 27 0.206 5
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0051716 Not Cancer Driver No 93 0.149 285 39 0.137 0
SYNGR1 SYNGR1 O43759 Synaptogyrin-1 chr22 GO:0051716 Not Cancer Driver No 26 0.112 48 5 0.104 0
SYT10 SYT10 Q6XYQ8 Synaptotagmin-10 chr12 GO:0051716 Not Cancer Driver No 155 0.296 163 56 0.344 0
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0051716 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYT12_ENST00000527043 SYT12 Q8IV01 Synaptotagmin-12 chr11 GO:0051716 Not Cancer Driver No 71 0.169 73 13 0.178 0
SYT13 SYT13 Q7L8C5 Synaptotagmin-13 chr11 GO:0051716 Not Cancer Driver No 71 0.167 133 16 0.12 0
SYT15 SYT15 Q9BQS2 Synaptotagmin-15 chr10 GO:0051716 Not Cancer Driver No 118 0.28 55 23 0.418 0
SYT17 SYT17 Q9BSW7 Synaptotagmin-17 chr16 GO:0051716 Not Cancer Driver No 76 0.16 150 37 0.247 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0051716 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 GO:0051716 Not Cancer Driver No 73 0.174 141 24 0.17 3
SYT3_ENST00000593901 SYT3 Q9BQG1 Synaptotagmin-3 chr19 GO:0051716 Not Cancer Driver No 119 0.202 268 44 0.164 0
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0051716 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0051716 Not Cancer Driver No 60 0.155 110 11 0.1 0
SYT6_ENST00000610222 SYT6 Q5T7P8 Synaptotagmin-6 chr1 GO:0051716 Not Cancer Driver No 98 0.192 137 18 0.131 0
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0051716 Not Cancer Driver No 63 0.156 132 25 0.189 0
SYT8 SYT8 Q8NBV8 Synaptotagmin-8 chr11 GO:0051716 Not Cancer Driver No 41 0.102 129 22 0.171 0
SYT9 SYT9 Q86SS6 Synaptotagmin-9 chr11 GO:0051716 Not Cancer Driver No 120 0.244 148 42 0.284 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0051716 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAC1 TAC1 P20366 Protachykinin-1 chr7 GO:0051716 Not Cancer Driver No 31 0.24 18 4 0.222 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0051716 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0051716 Not Cancer Driver No 42 0.099 302 26 0.086 0
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 GO:0051716 Not Cancer Driver No 68 0.152 115 13 0.113 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0051716 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0051716 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0051716 Census, Compendium Yes 123 0.166 352 57 0.162 2
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0051716 Not Cancer Driver No 21 0.198 33 7 0.212 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0051716 Not Cancer Driver No 39 0.207 25 2 0.08 0
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0051716 Not Cancer Driver No 81 0.133 179 25 0.14 1
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 GO:0051716 Not Cancer Driver No 66 0.148 220 31 0.141 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0051716 Not Cancer Driver No 65 0.134 75 15 0.2 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0051716 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0051716 Not Cancer Driver No 28 0.07 310 16 0.052 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0051716 Not Cancer Driver No 31 0.145 73 6 0.082 0
TEX14 TEX14 Q8IWB6 Inactive serine/threonine-protein kinase TEX14 chr17 GO:0051716 Not Cancer Driver No 214 0.143 872 115 0.132 0
TEX264_ENST00000416589 TEX264 Q9Y6I9 Testis-expressed protein 264 chr3 GO:0051716 Not Cancer Driver No 40 0.128 107 11 0.103 0
TF TF P02787 Serotransferrin chr3 GO:0051716 Not Cancer Driver No 135 0.193 21 5 0.238 2
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0051716 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0051716 Compendium Yes 61 0.18 285 52 0.182 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0051716 Not Cancer Driver No 87 0.104 331 39 0.118 0
TFPI2 TFPI2 P48307 Tissue factor pathway inhibitor 2 chr7 GO:0051716 Not Cancer Driver No 54 0.23 5 11 2.2 0
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0051716 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0051716 Census Yes 89 0.117 80 6 0.075 1
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0051716 Not Cancer Driver No 123 0.179 107 26 0.243 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0051716 Not Cancer Driver No 61 0.116 149 21 0.141 38
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0051716 Not Cancer Driver No 32 0.107 22 2 0.091 1
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0051716 Not Cancer Driver No 87 0.189 113 28 0.248 33
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0051716 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0051716 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0051716 Not Cancer Driver No 154 0.127 367 51 0.139 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0051716 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0051716 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLE4_ENST00000376552 TLE4 Q04727 Transducin-like enhancer protein 4 chr9 GO:0051716 Not Cancer Driver No 172 0.223 381 92 0.241 0
TLK2 TLK2 Q86UE8 Serine/threonine-protein kinase tousled-like 2 chr17 GO:0051716 Not Cancer Driver No 120 0.155 436 58 0.133 5
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0051716 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0051716 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0051716 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0051716 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0051716 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0051716 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0051716 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0051716 Not Cancer Driver No 180 0.173 30 7 0.233 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0051716 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMCO1 TMCO1 Q9UM00 Calcium load-activated calcium channel chr1 GO:0051716 Not Cancer Driver No 31 0.13 49 5 0.102 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0051716 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0051716 Not Cancer Driver No 101 0.176 458 89 0.194 0
TMEM109 TMEM109 Q9BVC6 Transmembrane protein 109 chr11 GO:0051716 Not Cancer Driver No 39 0.16 7 0 0.0 0
TMEM117 TMEM117 Q9H0C3 Transmembrane protein 117 chr12 GO:0051716 Not Cancer Driver No 91 0.177 70 12 0.171 0
TMEM150C TMEM150C B9EJG8 Transmembrane protein 150C chr4 GO:0051716 Not Cancer Driver No 38 0.153 0 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:0051716 Not Cancer Driver No 49 0.102 22 8 0.364 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0051716 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM199 TMEM199 Q8N511 Transmembrane protein 199 chr17 GO:0051716 Not Cancer Driver No 24 0.115 54 5 0.093 3
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0051716 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0051716 Not Cancer Driver No 47 0.162 37 7 0.189 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051716 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0051716 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0051716 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0051716 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0051716 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF8 TNFRSF8 P28908 Tumor necrosis factor receptor superfamily member 8 chr1 GO:0051716 Not Cancer Driver No 95 0.16 286 35 0.122 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0051716 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0051716 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0051716 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0051716 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0051716 Not Cancer Driver No 21 0.382 55 21 0.382 0
TOMM7 TOMM7 Q9P0U1 Mitochondrial import receptor subunit TOM7 homolog chr7 GO:0051716 Not Cancer Driver No 7 0.127 0 0 0.0 0
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0051716 Not Cancer Driver No 33 0.099 0 0 0.0 3
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0051716 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0051716 Not Cancer Driver No 32 0.133 134 20 0.149 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0051716 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0051716 Not Cancer Driver No 118 0.241 55 17 0.309 1
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0051716 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0051716 Census Yes 311 0.132 1990 266 0.134 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0051716 Not Cancer Driver No 59 0.205 244 54 0.221 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0051716 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0051716 Not Cancer Driver No 63 0.134 240 33 0.138 1
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0051716 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0051716 Not Cancer Driver No 226 0.188 957 167 0.175 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0051716 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0051716 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0051716 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0051716 Census, Compendium Yes 120 0.114 537 61 0.114 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0051716 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0051716 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0051716 Not Cancer Driver No 86 0.176 47 15 0.319 0
TROVE2 RO60 P10155 RNA-binding protein RO60 chr1 GO:0051716 Not Cancer Driver No 82 0.152 17 1 0.059 0
TRPA1 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0051716 Not Cancer Driver No 324 0.29 62 14 0.226 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0051716 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0051716 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0051716 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0051716 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSC1 TSC1 Q92574 Hamartin chr9 GO:0051716 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0051716 Census Yes 128 0.168 38 9 0.237 39
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0051716 Not Cancer Driver No 5 0.03 1 0 0.0 0
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 GO:0051716 Not Cancer Driver No 92 0.221 257 61 0.237 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 GO:0051716 Not Cancer Driver No 41 0.091 52 9 0.173 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0051716 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWISTNB POLR1F Q3B726 DNA-directed RNA polymerase I subunit RPA43 chr7 GO:0051716 Not Cancer Driver No 55 0.163 146 29 0.199 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0051716 Not Cancer Driver No 95 0.139 135 11 0.081 38
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0051716 Not Cancer Driver No 61 0.156 77 14 0.182 0
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0051716 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0051716 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0051716 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0051716 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0051716 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0051716 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0051716 Not Cancer Driver No 172 0.098 228 30 0.132 0
UBXN2A UBXN2A P68543 UBX domain-containing protein 2A chr2 GO:0051716 Not Cancer Driver No 37 0.143 58 11 0.19 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0051716 Not Cancer Driver No 33 0.148 34 7 0.206 4
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0051716 Not Cancer Driver No 43 0.14 1 0 0.0 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0051716 Not Cancer Driver No 31 0.1 11 3 0.273 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0051716 Not Cancer Driver No 26 0.085 100 7 0.07 0
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 GO:0051716 Not Cancer Driver No 169 0.109 161 20 0.124 0
UGGT2 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 GO:0051716 Not Cancer Driver No 190 0.125 64 6 0.094 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0051716 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT3A2 UGT3A2 Q3SY77 UDP-glucuronosyltransferase 3A2 chr5 GO:0051716 Not Cancer Driver No 169 0.323 0 0 0.0 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0051716 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 GO:0051716 Not Cancer Driver No 37 0.078 55 2 0.036 0
UMODL1_ENST00000408910 UMODL1 Q5DID0 Uromodulin-like 1 chr21 GO:0051716 Not Cancer Driver No 191 0.145 249 29 0.116 0
UMPS UMPS P11172 Uridine 5'-monophosphate synthase chr3 GO:0051716 Not Cancer Driver No 58 0.121 18 2 0.111 3
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0051716 Not Cancer Driver No 214 0.135 448 77 0.172 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0051716 Not Cancer Driver No 146 0.129 329 36 0.109 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0051716 Not Cancer Driver No 47 0.152 13 3 0.231 0
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 GO:0051716 Not Cancer Driver No 34 0.128 7 0 0.0 21
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0051716 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0051716 Not Cancer Driver No 30 0.087 326 29 0.089 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 GO:0051716 Not Cancer Driver No 92 0.115 425 49 0.115 0
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0051716 Not Cancer Driver No 151 0.14 311 25 0.08 0
USP45 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0051716 Not Cancer Driver No 96 0.118 275 28 0.102 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0051716 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0051716 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0051716 Census, Compendium Yes 122 0.109 602 69 0.115 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0051716 Not Cancer Driver No 89 0.127 243 28 0.115 0
UVSSA UVSSA Q2YD98 UV-stimulated scaffold protein A chr4 GO:0051716 Not Cancer Driver No 101 0.142 519 70 0.135 1
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0051716 Not Cancer Driver No 11 0.11 17 1 0.059 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 GO:0051716 Not Cancer Driver No 16 0.066 138 8 0.058 3
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0051716 Not Cancer Driver No 188 0.254 110 28 0.255 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0051716 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0051716 Not Cancer Driver No 133 0.109 543 61 0.112 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0051716 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0051716 Not Cancer Driver No 128 0.305 37 12 0.324 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0051716 Census, Compendium Yes 142 0.667 117 36 0.308 133
VIL1 VIL1 P09327 Villin-1 chr2 GO:0051716 Not Cancer Driver No 124 0.15 222 38 0.171 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0051716 Not Cancer Driver No 84 0.18 316 57 0.18 1
VPS26B VPS26B Q4G0F5 Vacuolar protein sorting-associated protein 26B chr11 GO:0051716 Not Cancer Driver No 45 0.134 52 5 0.096 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0051716 Not Cancer Driver No 106 0.164 571 95 0.166 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0051716 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0051716 Not Cancer Driver No 63 0.113 445 49 0.11 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0051716 Not Cancer Driver No 26 0.1 102 6 0.059 1
WDR35 WDR35 Q9P2L0 WD repeat-containing protein 35 chr2 GO:0051716 Not Cancer Driver No 137 0.116 42 3 0.071 6
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0051716 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0051716 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0051716 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0051716 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0051716 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0051716 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0051716 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0051716 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0051716 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0051716 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0051716 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0051716 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0051716 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 GO:0051716 Not Cancer Driver No 50 0.142 27 5 0.185 0
WNT9A WNT9A O14904 Protein Wnt-9a chr1 GO:0051716 Not Cancer Driver No 74 0.203 44 11 0.25 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0051716 Not Cancer Driver No 47 0.132 11 4 0.364 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0051716 Census, Compendium Yes 164 0.115 373 41 0.11 2
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 GO:0051716 Not Cancer Driver No 128 0.15 127 17 0.134 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0051716 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0051716 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0051716 Not Cancer Driver No 20 0.175 35 5 0.143 0
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0051716 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0051716 Census, Compendium Yes 88 0.094 479 48 0.1 2
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 GO:0051716 Not Cancer Driver No 103 0.148 70 15 0.214 4
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0051716 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0051716 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0051716 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0051716 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0051716 Not Cancer Driver No 213 0.125 577 65 0.113 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0051716 Not Cancer Driver No 51 0.101 489 49 0.1 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0051716 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0051716 Not Cancer Driver No 49 0.132 359 47 0.131 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0051716 Not Cancer Driver No 65 0.12 62 10 0.161 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0051716 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0051716 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0051716 Compendium Yes 151 0.204 433 80 0.185 4
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0051716 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0051716 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0051716 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0051716 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZFAND1 ZFAND1 Q8TCF1 AN1-type zinc finger protein 1 chr8 GO:0051716 Not Cancer Driver No 34 0.127 30 7 0.233 0
ZFAND2A ZFAND2A Q8N6M9 AN1-type zinc finger protein 2A chr7 GO:0051716 Not Cancer Driver No 14 0.097 8 0 0.0 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0051716 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0051716 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0051716 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0051716 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:0051716 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF236_ENST00000253159 ZNF236 Q9UL36 Zinc finger protein 236 chr18 GO:0051716 Not Cancer Driver No 270 0.146 977 152 0.156 0
ZNF277 ZNF277 Q9NRM2 Zinc finger protein 277 chr7 GO:0051716 Not Cancer Driver No 59 0.131 79 15 0.19 0
ZNF35 ZNF35 P13682 Zinc finger protein 35 chr3 GO:0051716 Not Cancer Driver No 66 0.125 192 17 0.089 0
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0051716 Not Cancer Driver No 8 0.047 153 8 0.052 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0051716 Not Cancer Driver No 26 0.044 415 14 0.034 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0051716 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZYX ZYX Q15942 Zyxin chr7 GO:0051716 Not Cancer Driver No 83 0.145 385 52 0.135 0