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Total number of protein in "GO:0050790" GO term:  1335

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 GO:0050790 Not Cancer Driver No 74 0.124 36 6 0.167 0
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0050790 Not Cancer Driver No 34 0.097 18 1 0.056 4
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0050790 Census, Compendium Yes 55 0.108 360 39 0.108 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0050790 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0050790 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABR ABR Q12979 Active breakpoint cluster region-related protein chr17 GO:0050790 Not Cancer Driver No 122 0.142 184 36 0.196 0
ACAP1 ACAP1 Q15027 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 chr17 GO:0050790 Not Cancer Driver No 95 0.128 266 37 0.139 0
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 GO:0050790 Not Cancer Driver No 97 0.125 287 40 0.139 0
ACAP3 ACAP3 Q96P50 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 chr1 GO:0050790 Not Cancer Driver No 68 0.082 216 7 0.032 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0050790 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0050790 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0050790 Census, Compendium Yes 98 0.191 56 6 0.107 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0050790 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0050790 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0050790 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0050790 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADGRB3_ENST00000546190 ADGRB3 O60242 Adhesion G protein-coupled receptor B3 chr6 GO:0050790 Not Cancer Driver No 558 0.367 336 149 0.443 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0050790 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0050790 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0050790 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0050790 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 GO:0050790 Not Cancer Driver No 54 0.151 30 3 0.1 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0050790 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0050790 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0050790 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0050790 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0050790 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0050790 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGAP1 AGAP1 Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 chr2 GO:0050790 Not Cancer Driver No 163 0.19 403 81 0.201 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0050790 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGAP3_ENST00000622464 AGAP3 Q96P47 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 chr7 GO:0050790 Not Cancer Driver No 116 0.133 404 55 0.136 0
AGAP4 AGAP4 Q96P64 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 chr10 GO:0050790 Not Cancer Driver No 25 0.038 328 8 0.024 0
AGAP5 AGAP5 A6NIR3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 chr10 GO:0050790 Not Cancer Driver No 57 0.083 353 34 0.096 0
AGAP6_ENST00000374056 AGAP6 Q5VW22 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6 chr10 GO:0050790 Not Cancer Driver No 107 0.161 330 45 0.136 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0050790 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGFG1_ENST00000310078 AGFG1 P52594 Arf-GAP domain and FG repeat-containing protein 1 chr2 GO:0050790 Not Cancer Driver No 60 0.107 395 50 0.127 0
AGFG2 AGFG2 O95081 Arf-GAP domain and FG repeat-containing protein 2 chr7 GO:0050790 Not Cancer Driver No 62 0.129 376 49 0.13 0
AGT AGT P01019 Angiotensinogen chr1 GO:0050790 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0050790 Not Cancer Driver No 95 0.265 0 0 0.0 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0050790 Not Cancer Driver No 98 0.27 0 0 0.0 0
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0050790 Not Cancer Driver No 36 0.118 87 9 0.103 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 GO:0050790 Not Cancer Driver No 46 0.144 61 8 0.131 0
AIP AIP O00170 AH receptor-interacting protein chr11 GO:0050790 Not Cancer Driver No 32 0.097 64 9 0.141 1
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0050790 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0050790 Census Yes 474 0.121 2281 268 0.117 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0050790 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0050790 Census Yes 77 0.16 84 9 0.107 2
ALDH1A1 ALDH1A1 P00352 Aldehyde dehydrogenase 1A1 chr9 GO:0050790 Not Cancer Driver No 65 0.13 29 3 0.103 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0050790 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0050790 Not Cancer Driver No 7 0.046 31 0 0.0 0
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0050790 Not Cancer Driver No 17 0.106 1 0 0.0 0
ALS2CL ALS2CL Q60I27 ALS2 C-terminal-like protein chr3 GO:0050790 Not Cancer Driver No 114 0.12 134 9 0.067 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0050790 Not Cancer Driver No 173 0.133 788 103 0.131 0
AMOT AMOT Q4VCS5 Angiomotin chrX GO:0050790 Not Cancer Driver No 161 0.149 909 128 0.141 0
ANG ANG P03950 Angiogenin chr14 GO:0050790 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0050790 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0050790 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0050790 Not Cancer Driver No 52 0.113 154 26 0.169 0
ANGPTL4 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 GO:0050790 Not Cancer Driver No 47 0.116 180 22 0.122 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0050790 Not Cancer Driver No 127 0.135 521 71 0.136 2
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0050790 Not Cancer Driver No 145 0.138 239 33 0.138 0
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0050790 Not Cancer Driver No 105 0.186 183 44 0.24 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0050790 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA8L1 ANXA8L1 Q5VT79 Annexin A8-like protein 1 chr10 GO:0050790 Not Cancer Driver No 5 0.015 37 0 0.0 0
AOC3 AOC3 Q16853 Membrane primary amine oxidase chr17 GO:0050790 Not Cancer Driver No 112 0.147 101 13 0.129 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0050790 Not Cancer Driver No 126 0.115 316 31 0.098 1
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0050790 Not Cancer Driver No 127 0.102 17 1 0.059 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0050790 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0050790 Not Cancer Driver No 117 0.051 1725 78 0.045 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0050790 Not Cancer Driver No 73 0.327 0 0 0.0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0050790 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0050790 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0050790 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0050790 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0050790 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0050790 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0050790 Not Cancer Driver No 14 0.141 12 2 0.167 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0050790 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0050790 Not Cancer Driver No 67 0.194 0 0 0.0 0
APOPT1 COA8 Q96IL0 Cytochrome c oxidase assembly factor 8 chr14 GO:0050790 Not Cancer Driver No 23 0.112 48 4 0.083 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0050790 Not Cancer Driver No 128 0.166 418 71 0.17 17
AREG AREG P15514 Amphiregulin chr4 GO:0050790 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0050790 Not Cancer Driver No 17 0.094 0 0 0.0 0
ARFGAP1_ENST00000370283 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 GO:0050790 Not Cancer Driver No 60 0.148 264 37 0.14 0
ARFGAP2 ARFGAP2 Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 chr11 GO:0050790 Not Cancer Driver No 62 0.119 345 40 0.116 0
ARFGAP3 ARFGAP3 Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 chr22 GO:0050790 Not Cancer Driver No 53 0.103 321 38 0.118 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0050790 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 GO:0050790 Not Cancer Driver No 254 0.142 358 63 0.176 0
ARFGEF3 ARFGEF3 Q5TH69 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 chr6 GO:0050790 Not Cancer Driver No 258 0.119 584 58 0.099 0
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 GO:0050790 Not Cancer Driver No 39 0.089 90 8 0.089 0
ARHGAP10 ARHGAP10 A1A4S6 Rho GTPase-activating protein 10 chr4 GO:0050790 Not Cancer Driver No 100 0.127 267 41 0.154 0
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 GO:0050790 Not Cancer Driver No 123 0.14 547 72 0.132 0
ARHGAP18 ARHGAP18 Q8N392 Rho GTPase-activating protein 18 chr6 GO:0050790 Not Cancer Driver No 87 0.131 297 39 0.131 0
ARHGAP19 ARHGAP19 Q14CB8 Rho GTPase-activating protein 19 chr10 GO:0050790 Not Cancer Driver No 70 0.142 179 21 0.117 0
ARHGAP20 ARHGAP20 Q9P2F6 Rho GTPase-activating protein 20 chr11 GO:0050790 Not Cancer Driver No 193 0.162 607 94 0.155 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 GO:0050790 Not Cancer Driver No 242 0.124 1612 204 0.127 0
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 GO:0050790 Not Cancer Driver No 138 0.198 449 90 0.2 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0050790 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP25 ARHGAP25 P42331 Rho GTPase-activating protein 25 chr2 GO:0050790 Not Cancer Driver No 120 0.186 339 62 0.183 0
ARHGAP26 ARHGAP26 Q9UNA1 Rho GTPase-activating protein 26 chr5 GO:0050790 Census Yes 99 0.122 259 26 0.1 1
ARHGAP28_ENST00000383472 ARHGAP28 Q9P2N2 Rho GTPase-activating protein 28 chr18 GO:0050790 Not Cancer Driver No 121 0.166 336 45 0.134 0
ARHGAP29 ARHGAP29 Q52LW3 Rho GTPase-activating protein 29 chr1 GO:0050790 Not Cancer Driver No 182 0.144 579 94 0.162 0
ARHGAP30 ARHGAP30 Q7Z6I6 Rho GTPase-activating protein 30 chr1 GO:0050790 Not Cancer Driver No 199 0.181 854 151 0.177 0
ARHGAP31 ARHGAP31 Q2M1Z3 Rho GTPase-activating protein 31 chr3 GO:0050790 Not Cancer Driver No 272 0.188 1170 226 0.193 0
ARHGAP32 ARHGAP32 A7KAX9 Rho GTPase-activating protein 32 chr11 GO:0050790 Not Cancer Driver No 268 0.128 1476 193 0.131 0
ARHGAP36 ARHGAP36 Q6ZRI8 Rho GTPase-activating protein 36 chrX GO:0050790 Not Cancer Driver No 194 0.355 132 61 0.462 0
ARHGAP39_ENST00000276826 ARHGAP39 Q9C0H5 Rho GTPase-activating protein 39 chr8 GO:0050790 Not Cancer Driver No 120 0.111 613 61 0.1 0
ARHGAP40 ARHGAP40 Q5TG30 Rho GTPase-activating protein 40 chr20 GO:0050790 Not Cancer Driver No 22 0.035 263 9 0.034 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:0050790 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 GO:0050790 Not Cancer Driver No 110 0.097 679 68 0.1 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX GO:0050790 Not Cancer Driver No 125 0.132 464 76 0.164 0
ARHGAP5 ARHGAP5 Q13017 Rho GTPase-activating protein 5 chr14 GO:0050790 Census, Compendium Yes 249 0.166 418 50 0.12 0
ARHGAP8 ARHGAP8 P85298 Rho GTPase-activating protein 8 chr22 GO:0050790 Not Cancer Driver No 65 0.14 75 13 0.173 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 GO:0050790 Not Cancer Driver No 25 0.123 50 6 0.12 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0050790 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARHGDIG ARHGDIG Q99819 Rho GDP-dissociation inhibitor 3 chr16 GO:0050790 Not Cancer Driver No 11 0.049 13 1 0.077 0
ARHGEF10L ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0050790 Census, Compendium Yes 155 0.121 431 47 0.109 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0050790 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF11_ENST00000361409 ARHGEF11 O15085 Rho guanine nucleotide exchange factor 11 chr1 GO:0050790 Not Cancer Driver No 213 0.14 1036 138 0.133 0
ARHGEF12 ARHGEF12 Q9NZN5 Rho guanine nucleotide exchange factor 12 chr11 GO:0050790 Census, Compendium Yes 212 0.137 972 150 0.154 0
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0050790 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 GO:0050790 Not Cancer Driver No 68 0.096 297 13 0.044 0
ARHGEF17 ARHGEF17 Q96PE2 Rho guanine nucleotide exchange factor 17 chr11 GO:0050790 Not Cancer Driver No 237 0.115 1408 170 0.121 0
ARHGEF19 ARHGEF19 Q8IW93 Rho guanine nucleotide exchange factor 19 chr1 GO:0050790 Not Cancer Driver No 82 0.102 365 36 0.099 0
ARHGEF1_ENST00000354532 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 GO:0050790 Not Cancer Driver No 127 0.139 457 67 0.147 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0050790 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF25_ENST00000286494 ARHGEF25 Q86VW2 Rho guanine nucleotide exchange factor 25 chr12 GO:0050790 Not Cancer Driver No 80 0.138 241 35 0.145 0
ARHGEF26 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 GO:0050790 Not Cancer Driver No 164 0.188 475 86 0.181 0
ARHGEF28_ENST00000426542 ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 chr5 GO:0050790 Not Cancer Driver No 188 0.11 764 88 0.115 0
ARHGEF33_ENST00000398800 ARHGEF33 A8MVX0 Rho guanine nucleotide exchange factor 33 chr2 GO:0050790 Not Cancer Driver No 57 0.068 580 42 0.072 0
ARHGEF37 ARHGEF37 A1IGU5 Rho guanine nucleotide exchange factor 37 chr5 GO:0050790 Not Cancer Driver No 88 0.13 165 31 0.188 0
ARHGEF38 ARHGEF38 Q9NXL2 Rho guanine nucleotide exchange factor 38 chr4 GO:0050790 Not Cancer Driver No 30 0.039 156 12 0.077 0
ARHGEF39 ARHGEF39 Q8N4T4 Rho guanine nucleotide exchange factor 39 chr9 GO:0050790 Not Cancer Driver No 45 0.134 56 5 0.089 0
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:0050790 Not Cancer Driver No 70 0.133 154 17 0.11 0
ARHGEF4 ARHGEF4 Q9NR80 Rho guanine nucleotide exchange factor 4 chr2 GO:0050790 Not Cancer Driver No 114 0.165 287 61 0.213 0
ARHGEF40 ARHGEF40 Q8TER5 Rho guanine nucleotide exchange factor 40 chr14 GO:0050790 Not Cancer Driver No 161 0.106 781 75 0.096 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0050790 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX GO:0050790 Not Cancer Driver No 158 0.204 223 45 0.202 0
ARHGEF9 ARHGEF9 O43307 Rho guanine nucleotide exchange factor 9 chrX GO:0050790 Not Cancer Driver No 97 0.188 88 7 0.08 2
ARL1 ARL1 P40616 ADP-ribosylation factor-like protein 1 chr12 GO:0050790 Not Cancer Driver No 17 0.094 4 0 0.0 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0050790 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARL2BP ARL2BP Q9Y2Y0 ADP-ribosylation factor-like protein 2-binding protein chr16 GO:0050790 Not Cancer Driver No 16 0.098 5 0 0.0 1
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0050790 Not Cancer Driver No 46 0.112 122 22 0.18 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 GO:0050790 Not Cancer Driver No 52 0.126 95 12 0.126 0
ARRDC4 ARRDC4 Q8NCT1 Arrestin domain-containing protein 4 chr15 GO:0050790 Not Cancer Driver No 52 0.124 53 12 0.226 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0050790 Not Cancer Driver No 109 0.144 373 53 0.142 1
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0050790 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0050790 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0050790 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP6V1H_ENST00000396774 ATP6V1H Q9UI12 V-type proton ATPase subunit H chr8 GO:0050790 Not Cancer Driver No 76 0.157 35 2 0.057 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0050790 Not Cancer Driver No 228 0.152 171 46 0.269 52
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0050790 Not Cancer Driver No 41 0.1 122 13 0.107 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0050790 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0050790 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0050790 Census, Compendium Yes 120 0.139 619 88 0.142 4
AZIN1 AZIN1 O14977 Antizyme inhibitor 1 chr8 GO:0050790 Not Cancer Driver No 39 0.087 10 2 0.2 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0050790 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 GO:0050790 Not Cancer Driver No 17 0.081 112 9 0.08 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0050790 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:0050790 Not Cancer Driver No 37 0.083 63 7 0.111 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0050790 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0050790 Census Yes 30 0.156 39 2 0.051 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0050790 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0050790 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL2L12 BCL2L12 Q9HB09 Bcl-2-like protein 12 chr19 GO:0050790 Census, Compendium Yes 40 0.12 132 10 0.076 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0050790 Census, Compendium Yes 146 0.115 603 69 0.114 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0050790 Not Cancer Driver No 45 0.1 190 19 0.1 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0050790 Not Cancer Driver No 124 0.127 656 86 0.131 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0050790 Not Cancer Driver No 65 0.11 456 42 0.092 5
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0050790 Not Cancer Driver No 50 0.153 150 30 0.2 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0050790 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 GO:0050790 Not Cancer Driver No 124 0.107 827 89 0.108 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 GO:0050790 Not Cancer Driver No 28 0.089 144 18 0.125 0
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 GO:0050790 Not Cancer Driver No 16 0.086 133 10 0.075 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:0050790 Not Cancer Driver No 387 0.127 3023 384 0.127 0
BOD1L2 BOD1L2 Q8IYS8 Biorientation of chromosomes in cell division protein 1-like 2 chr18 GO:0050790 Not Cancer Driver No 29 0.169 144 26 0.181 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0050790 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0050790 Not Cancer Driver No 39 0.123 74 7 0.095 0
BRPF1_ENST00000457855 BRPF1 P55201 Peregrin chr3 GO:0050790 Not Cancer Driver No 148 0.122 753 95 0.126 2
BTC BTC P35070 Probetacellulin chr4 GO:0050790 Not Cancer Driver No 29 0.163 12 5 0.417 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0050790 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0050790 Not Cancer Driver No 80 0.132 45 4 0.089 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 GO:0050790 Census Yes 96 0.091 480 35 0.073 7
BUB3 BUB3 O43684 Mitotic checkpoint protein BUB3 chr10 GO:0050790 Not Cancer Driver No 46 0.14 60 6 0.1 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0050790 Not Cancer Driver No 71 0.203 0 0 0.0 0
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 GO:0050790 Not Cancer Driver No 38 0.11 29 2 0.069 0
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 GO:0050790 Not Cancer Driver No 28 0.078 234 18 0.077 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0050790 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0050790 Census, Compendium Yes 342 0.158 736 126 0.171 2
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0050790 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0050790 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0050790 Not Cancer Driver No 17 0.114 115 10 0.087 3
CALML3 CALML3 P27482 Calmodulin-like protein 3 chr10 GO:0050790 Not Cancer Driver No 34 0.228 105 28 0.267 0
CALML4 CALML4 Q96GE6 Calmodulin-like protein 4 chr15 GO:0050790 Not Cancer Driver No 21 0.107 81 4 0.049 0
CALML5 CALML5 Q9NZT1 Calmodulin-like protein 5 chr10 GO:0050790 Not Cancer Driver No 34 0.233 98 21 0.214 0
CALML6 CALML6 Q8TD86 Calmodulin-like protein 6 chr1 GO:0050790 Not Cancer Driver No 23 0.127 51 4 0.078 0
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0050790 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0050790 Not Cancer Driver No 68 0.095 32 2 0.062 1
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0050790 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0050790 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0050790 Not Cancer Driver No 99 0.099 296 36 0.122 11
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0050790 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD18 CARD18 P57730 Caspase recruitment domain-containing protein 18 chr11 GO:0050790 Not Cancer Driver No 24 0.267 14 1 0.071 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0050790 Not Cancer Driver No 53 0.099 126 7 0.056 1
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0050790 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0050790 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0050790 Census Yes 49 0.118 71 7 0.099 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0050790 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 GO:0050790 Not Cancer Driver No 73 0.103 708 73 0.103 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0050790 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0050790 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0050790 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0050790 Census Yes 160 0.163 562 104 0.185 0
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0050790 Census Yes 60 0.127 128 21 0.164 0
CBX8 CBX8 Q9HC52 Chromobox protein homolog 8 chr17 GO:0050790 Not Cancer Driver No 59 0.152 309 51 0.165 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:0050790 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0050790 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCDC88C CCDC88C Q9P219 Protein Daple chr14 GO:0050790 Not Cancer Driver No 270 0.133 1604 225 0.14 1
CCKBR CCKBR P32239 Gastrin/cholecystokinin type B receptor chr11 GO:0050790 Not Cancer Driver No 122 0.273 61 22 0.361 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0050790 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0050790 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0050790 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCNC CCNC P24863 Cyclin-C chr6 GO:0050790 Census Yes 32 0.113 33 3 0.091 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0050790 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0050790 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0050790 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0050790 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNL2 CCNL2 Q96S94 Cyclin-L2 chr1 GO:0050790 Not Cancer Driver No 77 0.148 251 33 0.131 0
CCNQ_ENST00000576892 CCNQ Q8N1B3 Cyclin-Q chrX GO:0050790 Not Cancer Driver No 32 0.129 23 0 0.0 0
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0050790 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0050790 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0050790 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0050790 Not Cancer Driver No 31 0.086 100 8 0.08 0
CCPG1_ENST00000310958 CCPG1 Q9ULG6 Cell cycle progression protein 1 chr15 GO:0050790 Not Cancer Driver No 95 0.125 509 64 0.126 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0050790 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0050790 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCS CCS O14618 Copper chaperone for superoxide dismutase chr11 GO:0050790 Not Cancer Driver No 28 0.102 105 10 0.095 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0050790 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0050790 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCZ1 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 GO:0050790 Not Cancer Driver No 40 0.083 43 3 0.07 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0050790 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0050790 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0050790 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0050790 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0050790 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0050790 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0050790 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0050790 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0050790 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC42EP2 CDC42EP2 O14613 Cdc42 effector protein 2 chr11 GO:0050790 Not Cancer Driver No 19 0.09 162 17 0.105 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0050790 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0050790 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0050790 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0050790 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0050790 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0050790 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0050790 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0050790 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0050790 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0050790 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0050790 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0050790 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0050790 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0050790 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2C_ENST00000371761 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 GO:0050790 Census, Compendium Yes 23 0.137 49 6 0.122 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0050790 Not Cancer Driver No 17 0.102 44 3 0.068 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0050790 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0050790 Not Cancer Driver No 207 0.152 105 10 0.095 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0050790 Not Cancer Driver No 29 0.083 19 0 0.0 1
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0050790 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHM CHM P24386 Rab proteins geranylgeranyltransferase component A 1 chrX GO:0050790 Not Cancer Driver No 113 0.173 179 40 0.223 3
CHML CHML P26374 Rab proteins geranylgeranyltransferase component A 2 chr1 GO:0050790 Not Cancer Driver No 91 0.139 197 25 0.127 0
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0050790 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 GO:0050790 Not Cancer Driver No 47 0.142 119 17 0.143 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0050790 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0050790 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0050790 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0050790 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0050790 Not Cancer Driver No 13 0.107 7 0 0.0 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 GO:0050790 Not Cancer Driver No 36 0.145 244 34 0.139 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0050790 Not Cancer Driver No 19 0.087 23 1 0.043 0
CISH_ENST00000348721 CISH Q9NSE2 Cytokine-inducible SH2-containing protein chr3 GO:0050790 Not Cancer Driver No 33 0.128 97 8 0.082 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0050790 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0050790 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0050790 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0050790 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLPS CLPS P04118 Colipase chr6 GO:0050790 Not Cancer Driver No 25 0.223 0 0 0.0 0
CLPSL1 CLPSL1 A2RUU4 Colipase-like protein 1 chr6 GO:0050790 Not Cancer Driver No 18 0.149 0 0 0.0 0
CLPSL2_ENST00000403376 CLPSL2 Q6UWE3 Colipase-like protein 2 chr6 GO:0050790 Not Cancer Driver No 11 0.11 0 0 0.0 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0050790 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0050790 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 GO:0050790 Not Cancer Driver No 57 0.158 21 4 0.19 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0050790 Not Cancer Driver No 25 0.12 14 2 0.143 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0050790 Not Cancer Driver No 61 0.129 84 13 0.155 0
COX11 COX11 Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial chr17 GO:0050790 Not Cancer Driver No 21 0.076 51 4 0.078 0
COX17_ENST00000497116 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 GO:0050790 Not Cancer Driver No 7 0.111 15 2 0.133 0
COX6A1 COX6A1 P12074 Cytochrome c oxidase subunit 6A1, mitochondrial chr12 GO:0050790 Not Cancer Driver No 17 0.156 48 5 0.104 0
COX6A2 COX6A2 Q02221 Cytochrome c oxidase subunit 6A2, mitochondrial chr16 GO:0050790 Not Cancer Driver No 14 0.144 42 8 0.19 2
CPEB2_ENST00000507071 CPEB2 Q7Z5Q1 Cytoplasmic polyadenylation element-binding protein 2 chr4 GO:0050790 Not Cancer Driver No 66 0.112 269 17 0.063 0
CPN2_ENST00000429275 CPN2 P22792 Carboxypeptidase N subunit 2 chr3 GO:0050790 Not Cancer Driver No 91 0.167 2 3 1.5 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0050790 Compendium Yes 383 0.188 151 42 0.278 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0050790 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0050790 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0050790 Not Cancer Driver No 38 0.125 160 25 0.156 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0050790 Not Cancer Driver No 72 0.121 100 12 0.12 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0050790 Census Yes 133 0.137 124 17 0.137 20
CSN2 CSN2 P05814 Beta-casein chr4 GO:0050790 Not Cancer Driver No 49 0.217 41 12 0.293 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0050790 Not Cancer Driver No 20 0.093 19 0 0.0 4
CST7 CST7 O76096 Cystatin-F chr20 GO:0050790 Not Cancer Driver No 12 0.083 15 2 0.133 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0050790 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0050790 Not Cancer Driver No 59 0.123 14 1 0.071 12
CWF19L1 CWF19L1 Q69YN2 CWF19-like protein 1 chr10 GO:0050790 Not Cancer Driver No 59 0.11 69 9 0.13 0
CXCL1 CXCL1 P09341 Growth-regulated alpha protein chr4 GO:0050790 Not Cancer Driver No 20 0.187 18 4 0.222 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0050790 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0050790 Not Cancer Driver No 11 0.101 0 0 0.0 0
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 GO:0050790 Not Cancer Driver No 17 0.113 58 2 0.034 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0050790 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0050790 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0050790 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0050790 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:0050790 Census, Compendium Yes 64 0.185 0 0 0.0 0
CYTH1_ENST00000446868 CYTH1 Q15438 Cytohesin-1 chr17 GO:0050790 Not Cancer Driver No 59 0.148 93 15 0.161 0
CYTH2_ENST00000641098 CYTH2 Q99418 Cytohesin-2 chr19 GO:0050790 Not Cancer Driver No 55 0.138 93 12 0.129 0
CYTH3_ENST00000396741 CYTH3 O43739 Cytohesin-3 chr7 GO:0050790 Not Cancer Driver No 49 0.122 96 12 0.125 0
CYTH4 CYTH4 Q9UIA0 Cytohesin-4 chr22 GO:0050790 Not Cancer Driver No 70 0.178 52 10 0.192 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0050790 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0050790 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 GO:0050790 Not Cancer Driver No 7 0.062 0 0 0.0 0
DAOA_ENST00000375936 DAOA P59103 D-amino acid oxidase activator chr13 GO:0050790 Not Cancer Driver No 45 0.294 53 20 0.377 0
DBI_ENST00000355857 DBI P07108 Acyl-CoA-binding protein chr2 GO:0050790 Not Cancer Driver No 13 0.149 27 6 0.222 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0050790 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 GO:0050790 Not Cancer Driver No 34 0.131 13 0 0.0 0
DCUN1D2 DCUN1D2 Q6PH85 DCN1-like protein 2 chr13 GO:0050790 Not Cancer Driver No 36 0.139 29 7 0.241 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0050790 Not Cancer Driver No 36 0.118 118 9 0.076 0
DCUN1D4_ENST00000334635 DCUN1D4 Q92564 DCN1-like protein 4 chr4 GO:0050790 Not Cancer Driver No 51 0.175 57 12 0.211 0
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0050790 Not Cancer Driver No 18 0.076 7 0 0.0 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0050790 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0050790 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 GO:0050790 Not Cancer Driver No 34 0.075 13 3 0.231 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0050790 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0050790 Not Cancer Driver No 154 0.159 280 55 0.196 1
DEF6 DEF6 Q9H4E7 Differentially expressed in FDCP 6 homolog chr6 GO:0050790 Not Cancer Driver No 72 0.114 336 30 0.089 0
DENND1A DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 GO:0050790 Not Cancer Driver No 117 0.116 589 76 0.129 0
DENND1C DENND1C Q8IV53 DENN domain-containing protein 1C chr19 GO:0050790 Not Cancer Driver No 102 0.127 369 54 0.146 0
DENND2A_ENST00000496613 DENND2A Q9ULE3 DENN domain-containing protein 2A chr7 GO:0050790 Not Cancer Driver No 189 0.187 539 109 0.202 0
DENND2C_ENST00000393277 DENND2C Q68D51 DENN domain-containing protein 2C chr1 GO:0050790 Not Cancer Driver No 177 0.191 351 69 0.197 0
DENND2D DENND2D Q9H6A0 DENN domain-containing protein 2D chr1 GO:0050790 Not Cancer Driver No 67 0.142 54 6 0.111 0
DENND3 DENND3 A2RUS2 DENN domain-containing protein 3 chr8 GO:0050790 Not Cancer Driver No 192 0.16 118 22 0.186 0
DENND4A_ENST00000431932 DENND4A Q7Z401 C-myc promoter-binding protein chr15 GO:0050790 Not Cancer Driver No 199 0.107 570 64 0.112 0
DENND4B DENND4B O75064 DENN domain-containing protein 4B chr1 GO:0050790 Not Cancer Driver No 201 0.134 498 72 0.145 0
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 GO:0050790 Not Cancer Driver No 190 0.1 710 69 0.097 0
DENND5A DENND5A Q6IQ26 DENN domain-containing protein 5A chr11 GO:0050790 Not Cancer Driver No 134 0.104 231 21 0.091 0
DENND5B_ENST00000389082 DENND5B Q6ZUT9 DENN domain-containing protein 5B chr12 GO:0050790 Not Cancer Driver No 171 0.134 194 23 0.119 0
DENND6A DENND6A Q8IWF6 Protein DENND6A chr3 GO:0050790 Not Cancer Driver No 54 0.089 69 2 0.029 0
DENND6B DENND6B Q8NEG7 Protein DENND6B chr22 GO:0050790 Not Cancer Driver No 46 0.079 53 3 0.057 0
DEPDC1 DEPDC1 Q5TB30 DEP domain-containing protein 1A chr1 GO:0050790 Not Cancer Driver No 98 0.121 199 19 0.095 0
DEPDC1B DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 GO:0050790 Not Cancer Driver No 76 0.144 52 6 0.115 0
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 GO:0050790 Not Cancer Driver No 226 0.141 575 91 0.158 7
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0050790 Not Cancer Driver No 47 0.142 113 18 0.159 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0050790 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0050790 Not Cancer Driver No 87 0.094 410 42 0.102 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0050790 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0050790 Compendium Yes 182 0.143 331 42 0.127 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0050790 Not Cancer Driver No 62 0.259 54 8 0.148 1
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0050790 Not Cancer Driver No 56 0.13 9 0 0.0 0
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:0050790 Compendium Yes 121 0.126 235 32 0.136 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0050790 Not Cancer Driver No 62 0.121 145 29 0.2 24
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0050790 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0050790 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0050790 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMPK_ENST00000291270 DMPK Q09013 Myotonin-protein kinase chr19 GO:0050790 Not Cancer Driver No 54 0.086 220 14 0.064 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0050790 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0050790 Not Cancer Driver No 50 0.104 152 21 0.138 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0050790 Not Cancer Driver No 67 0.091 212 23 0.108 7
DNMBP DNMBP Q6XZF7 Dynamin-binding protein chr10 GO:0050790 Not Cancer Driver No 208 0.132 758 92 0.121 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0050790 Not Cancer Driver No 83 0.215 10 1 0.1 0
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0050790 Not Cancer Driver No 240 0.129 360 52 0.144 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 GO:0050790 Not Cancer Driver No 480 0.262 266 79 0.297 2
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0050790 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK4 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 GO:0050790 Not Cancer Driver No 331 0.168 397 80 0.202 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0050790 Not Cancer Driver No 278 0.149 330 45 0.136 0
DOCK6 DOCK6 Q96HP0 Dedicator of cytokinesis protein 6 chr19 GO:0050790 Not Cancer Driver No 203 0.099 496 57 0.115 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0050790 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 GO:0050790 Not Cancer Driver No 52 0.103 286 27 0.094 19
DPM2 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 GO:0050790 Not Cancer Driver No 9 0.107 0 0 0.0 1
DPM3_ENST00000341298 DPM3 Q9P2X0 Dolichol-phosphate mannosyltransferase subunit 3 chr1 GO:0050790 Not Cancer Driver No 8 0.087 0 0 0.0 1
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0050790 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0050790 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0050790 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0050790 Not Cancer Driver No 28 0.071 41 4 0.098 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0050790 Not Cancer Driver No 49 0.14 210 25 0.119 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0050790 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0050790 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0050790 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0050790 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0050790 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0050790 Not Cancer Driver No 84 0.457 0 0 0.0 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0050790 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0050790 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0050790 Not Cancer Driver No 54 0.257 78 21 0.269 0
ECSIT ECSIT Q9BQ95 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial chr19 GO:0050790 Not Cancer Driver No 58 0.135 146 29 0.199 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0050790 Not Cancer Driver No 104 0.114 284 33 0.116 0
ECT2L ECT2L Q008S8 Epithelial cell-transforming sequence 2 oncogene-like chr6 GO:0050790 Census Yes 131 0.145 31 7 0.226 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0050790 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0050790 Not Cancer Driver No 21 0.118 87 13 0.149 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0050790 Not Cancer Driver No 69 0.29 140 44 0.314 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0050790 Not Cancer Driver No 112 0.253 56 19 0.339 6
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 GO:0050790 Census Yes 64 0.145 79 11 0.139 6
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0050790 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 GO:0050790 Not Cancer Driver No 74 0.16 121 17 0.14 3
EEF1B2_ENST00000236957 EEF1B2 P24534 Elongation factor 1-beta chr2 GO:0050790 Not Cancer Driver No 63 0.28 71 11 0.155 0
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 GO:0050790 Not Cancer Driver No 40 0.142 153 22 0.144 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0050790 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0050790 Not Cancer Driver No 24 0.101 31 11 0.355 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0050790 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0050790 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0050790 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 GO:0050790 Not Cancer Driver No 35 0.082 206 8 0.039 2
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0050790 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0050790 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2B1 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 GO:0050790 Not Cancer Driver No 33 0.108 0 0 0.0 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0050790 Not Cancer Driver No 40 0.114 83 11 0.133 9
EIF2B3 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 GO:0050790 Not Cancer Driver No 54 0.119 28 9 0.321 5
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 GO:0050790 Not Cancer Driver No 57 0.109 212 29 0.137 7
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 GO:0050790 Not Cancer Driver No 76 0.105 179 16 0.089 29
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0050790 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:0050790 Census Yes 77 0.189 27 14 0.519 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 GO:0050790 Not Cancer Driver No 64 0.148 185 23 0.124 0
ELMO1_ENST00000448602 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 GO:0050790 Not Cancer Driver No 199 0.274 98 22 0.224 0
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0050790 Not Cancer Driver No 60 0.11 19 4 0.211 0
ELP4_ENST00000640961 ELP4 Q96EB1 Elongator complex protein 4 chr11 GO:0050790 Not Cancer Driver No 60 0.142 55 4 0.073 0
EPGN EPGN Q6UW88 Epigen chr4 GO:0050790 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0050790 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0050790 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0050790 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0050790 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:0050790 Not Cancer Driver No 61 0.1 22 1 0.045 0
EPS8L1 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 GO:0050790 Not Cancer Driver No 116 0.16 521 96 0.184 0
EPS8L2_ENST00000530636 EPS8L2 Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 chr11 GO:0050790 Not Cancer Driver No 68 0.095 372 31 0.083 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0050790 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0050790 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0050790 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0050790 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0050790 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0050790 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0050790 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0050790 Not Cancer Driver No 55 0.119 297 37 0.125 0
ETFBKMT_ENST00000412352 ETFBKMT Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase chr12 GO:0050790 Not Cancer Driver No 25 0.095 0 0 0.0 0
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 GO:0050790 Not Cancer Driver No 70 0.088 381 27 0.071 0
EVI5_ENST00000370331 EVI5 O60447 Ecotropic viral integration site 5 protein homolog chr1 GO:0050790 Not Cancer Driver No 115 0.142 416 61 0.147 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0050790 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:0050790 Not Cancer Driver No 115 0.185 97 25 0.258 10
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0050790 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0050790 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAM13A FAM13A O94988 Protein FAM13A chr4 GO:0050790 Not Cancer Driver No 139 0.136 630 81 0.129 0
FAM13B FAM13B Q9NYF5 Protein FAM13B chr5 GO:0050790 Not Cancer Driver No 93 0.102 575 64 0.111 0
FAM173A ANTKMT Q9BQD7 Adenine nucleotide translocase lysine N-methyltransferase chr16 GO:0050790 Not Cancer Driver No 10 0.043 37 3 0.081 0
FAM173B ATPSCKMT Q6P4H8 ATP synthase subunit C lysine N-methyltransferase chr5 GO:0050790 Not Cancer Driver No 41 0.176 10 1 0.1 0
FAM45A DENND10 Q8TCE6 DENN domain-containing protein 10 chr10 GO:0050790 Not Cancer Driver No 33 0.092 13 1 0.077 0
FAM47E FAM47E Q6ZV65 Protein FAM47E chr4 GO:0050790 Not Cancer Driver No 21 0.053 143 6 0.042 0
FARP1_ENST00000319562 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 GO:0050790 Not Cancer Driver No 147 0.141 315 60 0.19 0
FARP2 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 GO:0050790 Not Cancer Driver No 133 0.126 250 39 0.156 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0050790 Census, Compendium Yes 55 0.164 62 18 0.29 22
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0050790 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0050790 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXO8 FBXO8 Q9NRD0 F-box only protein 8 chr4 GO:0050790 Not Cancer Driver No 46 0.144 25 1 0.04 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0050790 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0050790 Not Cancer Driver No 41 0.128 130 22 0.169 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0050790 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0050790 Not Cancer Driver No 193 0.263 217 44 0.203 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0050790 Not Cancer Driver No 12 0.065 61 2 0.033 0
FDX2 FDX2 Q6P4F2 Ferredoxin-2, mitochondrial chr19 GO:0050790 Not Cancer Driver No 26 0.14 102 14 0.137 1
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 GO:0050790 Not Cancer Driver No 68 0.102 162 22 0.136 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0050790 Not Cancer Driver No 69 0.11 33 3 0.091 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0050790 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0050790 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0050790 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0050790 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0050790 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0050790 Not Cancer Driver No 43 0.108 272 33 0.121 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0050790 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0050790 Not Cancer Driver No 85 0.161 52 8 0.154 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0050790 Not Cancer Driver No 46 0.1 42 3 0.071 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0050790 Not Cancer Driver No 15 0.139 39 7 0.179 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0050790 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0050790 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0050790 Census, Compendium Yes 200 0.201 64 27 0.422 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:0050790 Not Cancer Driver No 43 0.113 92 12 0.13 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0050790 Compendium Yes 70 0.153 258 34 0.132 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0050790 Not Cancer Driver No 25 0.059 279 18 0.065 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0050790 Not Cancer Driver No 96 0.274 26 5 0.192 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0050790 Not Cancer Driver No 147 0.206 256 59 0.23 25
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0050790 Not Cancer Driver No 69 0.136 415 58 0.14 0
FTMT FTMT Q8N4E7 Ferritin, mitochondrial chr5 GO:0050790 Not Cancer Driver No 96 0.397 93 33 0.355 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0050790 Not Cancer Driver No 93 0.117 283 35 0.124 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0050790 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0050790 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0050790 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0050790 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0050790 Not Cancer Driver No 72 0.104 146 3 0.021 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0050790 Not Cancer Driver No 74 0.149 184 30 0.163 0
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0050790 Not Cancer Driver No 150 0.156 142 17 0.12 0
GABBR2 GABBR2 O75899 Gamma-aminobutyric acid type B receptor subunit 2 chr9 GO:0050790 Not Cancer Driver No 169 0.18 220 29 0.132 4
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0050790 Not Cancer Driver No 10 0.061 39 5 0.128 0
GALR1 GALR1 P47211 Galanin receptor type 1 chr18 GO:0050790 Not Cancer Driver No 68 0.195 32 2 0.062 0
GALR2 GALR2 O43603 Galanin receptor type 2 chr17 GO:0050790 Not Cancer Driver No 40 0.103 0 0 0.0 0
GALR3 GALR3 O60755 Galanin receptor type 3 chr22 GO:0050790 Not Cancer Driver No 15 0.041 53 0 0.0 0
GARNL3 GARNL3 Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 chr9 GO:0050790 Not Cancer Driver No 115 0.114 285 34 0.119 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0050790 Not Cancer Driver No 82 0.121 42 6 0.143 0
GBA3 GBA3 Q9H227 Cytosolic beta-glucosidase chr4 GO:0050790 Not Cancer Driver No 118 0.252 18 6 0.333 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 GO:0050790 Not Cancer Driver No 216 0.116 669 76 0.114 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0050790 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCHFR GCHFR P30047 GTP cyclohydrolase 1 feedback regulatory protein chr15 GO:0050790 Not Cancer Driver No 9 0.107 20 0 0.0 0
GCKR GCKR Q14397 Glucokinase regulatory protein chr2 GO:0050790 Not Cancer Driver No 98 0.157 85 27 0.318 0
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0050790 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0050790 Not Cancer Driver No 69 0.154 34 6 0.176 2
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 GO:0050790 Not Cancer Driver No 49 0.11 23 2 0.087 0
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0050790 Not Cancer Driver No 47 0.223 83 18 0.217 2
GDPGP1 GDPGP1 Q6ZNW5 GDP-D-glucose phosphorylase 1 chr15 GO:0050790 Not Cancer Driver No 44 0.114 83 9 0.108 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0050790 Not Cancer Driver No 57 0.135 199 29 0.146 2
GH1 GH1 P01241 Somatotropin chr17 GO:0050790 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0050790 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0050790 Not Cancer Driver No 173 0.271 229 66 0.288 19
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0050790 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0050790 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0050790 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0050790 Not Cancer Driver No 32 0.143 77 14 0.182 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0050790 Not Cancer Driver No 67 0.088 434 42 0.097 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 GO:0050790 Not Cancer Driver No 83 0.109 492 47 0.096 0
GLA GLA P06280 Alpha-galactosidase A chrX GO:0050790 Not Cancer Driver No 71 0.166 7 2 0.286 180
GM2A GM2A P17900 Ganglioside GM2 activator chr5 GO:0050790 Not Cancer Driver No 26 0.135 0 0 0.0 2
GMIP GMIP Q9P107 GEM-interacting protein chr19 GO:0050790 Not Cancer Driver No 124 0.128 597 67 0.112 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0050790 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0050790 Compendium Yes 52 0.138 32 4 0.125 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0050790 Compendium Yes 50 0.141 24 0 0.0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0050790 Not Cancer Driver No 42 0.119 11 0 0.0 1
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0050790 Not Cancer Driver No 43 0.123 39 6 0.154 3
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:0050790 Not Cancer Driver No 26 0.141 82 15 0.183 10
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0050790 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0050790 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPR87 GPR87 Q9BY21 G-protein coupled receptor 87 chr3 GO:0050790 Not Cancer Driver No 66 0.184 18 6 0.333 0
GPRC5A GPRC5A Q8NFJ5 Retinoic acid-induced protein 3 chr12 GO:0050790 Not Cancer Driver No 43 0.12 19 4 0.211 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0050790 Not Cancer Driver No 82 0.203 75 19 0.253 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 GO:0050790 Not Cancer Driver No 68 0.101 344 35 0.102 0
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 GO:0050790 Not Cancer Driver No 79 0.115 240 21 0.087 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 GO:0050790 Not Cancer Driver No 26 0.163 160 26 0.163 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0050790 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0050790 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0050790 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0050790 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM3 GRM3 Q14832 Metabotropic glutamate receptor 3 chr7 GO:0050790 Census Yes 323 0.367 8 3 0.375 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0050790 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0050790 Not Cancer Driver No 76 0.128 29 6 0.207 1
GRTP1_ENST00000375431 GRTP1 Q5TC63 Growth hormone-regulated TBC protein 1 chr13 GO:0050790 Not Cancer Driver No 58 0.173 39 3 0.077 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0050790 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0050790 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0050790 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0050790 Not Cancer Driver No 32 0.152 0 0 0.0 0
GTF2F1 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 GO:0050790 Not Cancer Driver No 63 0.122 426 48 0.113 0
GTF2H2_ENST00000330280 GTF2H2 Q13888 General transcription factor IIH subunit 2 chr5 GO:0050790 Not Cancer Driver No 7 0.018 43 1 0.023 0
GTF3C4 GTF3C4 Q9UKN8 General transcription factor 3C polypeptide 4 chr9 GO:0050790 Not Cancer Driver No 76 0.092 164 13 0.079 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0050790 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0050790 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0050790 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0050790 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0050790 Not Cancer Driver No 17 0.152 0 0 0.0 0
GZMA GZMA P12544 Granzyme A chr5 GO:0050790 Not Cancer Driver No 70 0.267 5 1 0.2 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0050790 Not Cancer Driver No 46 0.124 125 19 0.152 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 GO:0050790 Not Cancer Driver No 28 0.077 10 0 0.0 0
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0050790 Not Cancer Driver No 16 0.077 63 3 0.048 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0050790 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0050790 Not Cancer Driver No 286 0.283 631 178 0.282 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0050790 Not Cancer Driver No 173 0.125 974 135 0.139 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0050790 Not Cancer Driver No 487 0.1 1344 129 0.096 1
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 GO:0050790 Compendium Yes 718 0.149 971 150 0.154 1
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0050790 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 GO:0050790 Not Cancer Driver No 35 0.122 286 35 0.122 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0050790 Compendium Yes 233 0.32 43 16 0.372 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0050790 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0050790 Census Yes 118 0.143 435 51 0.117 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0050790 Not Cancer Driver No 128 0.105 559 51 0.091 0
HM13_ENST00000340852 HM13 Q8TCT9 Minor histocompatibility antigen H13 chr20 GO:0050790 Not Cancer Driver No 42 0.111 61 6 0.098 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0050790 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0050790 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0050790 Not Cancer Driver No 38 0.182 207 38 0.184 0
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0050790 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0050790 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0050790 Not Cancer Driver No 77 0.093 504 45 0.089 0
HP HP P00738 Haptoglobin chr16 GO:0050790 Not Cancer Driver No 39 0.096 57 2 0.035 1
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0050790 Not Cancer Driver No 24 0.124 42 4 0.095 3
HPS1_ENST00000613394 HPS1 Q92902 Hermansky-Pudlak syndrome 1 protein chr10 GO:0050790 Not Cancer Driver No 72 0.103 154 16 0.104 0
HPS4_ENST00000336873 HPS4 Q9NQG7 Hermansky-Pudlak syndrome 4 protein chr22 GO:0050790 Not Cancer Driver No 96 0.136 343 57 0.166 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0050790 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0050790 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0050790 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0050790 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPB2 HSPB2 Q16082 Heat shock protein beta-2 chr11 GO:0050790 Not Cancer Driver No 25 0.137 103 11 0.107 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0050790 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0050790 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:0050790 Not Cancer Driver No 336 0.107 666 69 0.104 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0050790 Not Cancer Driver No 52 0.11 8 1 0.125 0
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 GO:0050790 Not Cancer Driver No 146 0.108 364 39 0.107 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0050790 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0050790 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0050790 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0050790 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0050790 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0050790 Not Cancer Driver No 41 0.141 103 25 0.243 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0050790 Census, Compendium Yes 106 0.14 211 31 0.147 1
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0050790 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0050790 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0050790 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0050790 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0050790 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0050790 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0050790 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0050790 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0050790 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0050790 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0050790 Not Cancer Driver No 12 0.083 4 0 0.0 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 GO:0050790 Not Cancer Driver No 18 0.076 195 14 0.072 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0050790 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0050790 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0050790 Not Cancer Driver No 190 0.137 280 57 0.204 64
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0050790 Not Cancer Driver No 128 0.117 52 3 0.058 0
IPO7 IPO7 O95373 Importin-7 chr11 GO:0050790 Not Cancer Driver No 138 0.133 202 30 0.149 0
IQSEC2_ENST00000396435 IQSEC2 Q5JU85 IQ motif and SEC7 domain-containing protein 2 chrX GO:0050790 Not Cancer Driver No 163 0.11 1139 97 0.085 5
IQSEC3 IQSEC3 Q9UPP2 IQ motif and SEC7 domain-containing protein 3 chr12 GO:0050790 Not Cancer Driver No 166 0.14 682 85 0.125 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0050790 Compendium Yes 71 0.1 337 39 0.116 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0050790 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 GO:0050790 Not Cancer Driver No 14 0.084 24 3 0.125 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0050790 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0050790 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0050790 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0050790 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0050790 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 GO:0050790 Not Cancer Driver No 214 0.124 797 107 0.134 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 GO:0050790 Not Cancer Driver No 207 0.122 680 92 0.135 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0050790 Census, Compendium Yes 136 0.12 59 5 0.085 5
JMJD8_ENST00000609261 JMJD8 Q96S16 JmjC domain-containing protein 8 chr16 GO:0050790 Not Cancer Driver No 11 0.042 22 0 0.0 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0050790 Census Yes 35 0.106 281 25 0.089 0
KALRN_ENST00000360013 KALRN O60229 Kalirin chr3 GO:0050790 Not Cancer Driver No 544 0.182 732 128 0.175 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0050790 Not Cancer Driver No 107 0.129 266 27 0.102 0
KDM5A KDM5A P29375 Lysine-specific demethylase 5A chr12 GO:0050790 Census, Compendium Yes 220 0.13 503 66 0.131 0
KIAA1147 DENND11 A4D1U4 DENN domain-containing protein 11 chr7 GO:0050790 Not Cancer Driver No 54 0.119 82 0 0.0 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 GO:0050790 Not Cancer Driver No 245 0.138 683 113 0.165 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0050790 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0050790 Not Cancer Driver No 38 0.176 0 0 0.0 0
KNDC1 KNDC1 Q76NI1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 GO:0050790 Not Cancer Driver No 276 0.158 805 124 0.154 0
KRIT1_ENST00000394505 KRIT1 O00522 Krev interaction trapped protein 1 chr7 GO:0050790 Not Cancer Driver No 80 0.109 113 17 0.15 2
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 GO:0050790 Not Cancer Driver No 13 0.081 96 7 0.073 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 GO:0050790 Not Cancer Driver No 12 0.096 0 0 0.0 0
LAMTOR4 LAMTOR4 Q0VGL1 Ragulator complex protein LAMTOR4 chr7 GO:0050790 Not Cancer Driver No 8 0.081 4 0 0.0 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0050790 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0050790 Census, Compendium Yes 178 0.164 687 116 0.169 0
LEP LEP P41159 Leptin chr7 GO:0050790 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0050790 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0050790 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0050790 Not Cancer Driver No 57 0.132 112 19 0.17 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0050790 Not Cancer Driver No 79 0.264 98 19 0.194 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0050790 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0050790 Not Cancer Driver No 110 0.17 170 30 0.176 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 GO:0050790 Not Cancer Driver No 101 0.095 265 12 0.045 0
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 GO:0050790 Not Cancer Driver No 120 0.118 266 26 0.098 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:0050790 Not Cancer Driver No 120 0.135 447 70 0.157 0
LRCH1_ENST00000389798 LRCH1 Q9Y2L9 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 GO:0050790 Not Cancer Driver No 95 0.13 380 41 0.108 0
LRCOL1 LRCOL1 A6NCL2 Leucine-rich colipase-like protein 1 chr12 GO:0050790 Not Cancer Driver No 1 0.006 0 0 0.0 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0050790 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0050790 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0050790 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0050790 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0050790 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTB4R2 LTB4R2 Q9NPC1 Leukotriene B4 receptor 2 chr14 GO:0050790 Not Cancer Driver No 29 0.081 55 11 0.2 0
LTC4S LTC4S Q16873 Leukotriene C4 synthase chr5 GO:0050790 Not Cancer Driver No 3 0.02 0 0 0.0 0
LTF LTF P02788 Lactotransferrin chr3 GO:0050790 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0050790 Census Yes 95 0.186 84 12 0.143 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0050790 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0050790 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGEC2 MAGEC2 Q9UBF1 Melanoma-associated antigen C2 chrX GO:0050790 Not Cancer Driver No 170 0.456 129 69 0.535 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0050790 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0050790 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0050790 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0050790 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0050790 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0050790 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0050790 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0050790 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0050790 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0050790 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0050790 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0050790 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0050790 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0050790 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0050790 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0050790 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0050790 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0050790 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0050790 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0050790 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0050790 Not Cancer Driver No 128 0.169 750 126 0.168 18
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0050790 Not Cancer Driver No 47 0.145 5 2 0.4 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0050790 Not Cancer Driver No 90 0.102 389 44 0.113 0
MAT2B MAT2B Q9NZL9 Methionine adenosyltransferase 2 subunit beta chr5 GO:0050790 Not Cancer Driver No 42 0.126 59 8 0.136 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0050790 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCF2L2 MCF2L2 Q86YR7 Probable guanine nucleotide exchange factor MCF2L2 chr3 GO:0050790 Not Cancer Driver No 222 0.199 306 61 0.199 0
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:0050790 Not Cancer Driver No 173 0.152 410 54 0.132 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0050790 Not Cancer Driver No 218 0.236 124 33 0.266 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0050790 Not Cancer Driver No 104 0.115 275 38 0.138 1
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0050790 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEN1 MEN1 O00255 Menin chr11 GO:0050790 Census, Compendium Yes 73 0.119 228 15 0.066 90
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0050790 Census, Compendium Yes 226 0.163 62 15 0.242 19
MGAT5_ENST00000281923 MGAT5 Q09328 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A chr2 GO:0050790 Not Cancer Driver No 106 0.143 24 2 0.083 0
MGST2 MGST2 Q99735 Microsomal glutathione S-transferase 2 chr4 GO:0050790 Not Cancer Driver No 11 0.075 0 0 0.0 0
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0050790 Not Cancer Driver No 23 0.126 83 6 0.072 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0050790 Not Cancer Driver No 43 0.092 446 43 0.096 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0050790 Not Cancer Driver No 56 0.098 6 1 0.167 22
MMP15 MMP15 P51511 Matrix metalloproteinase-15 chr16 GO:0050790 Not Cancer Driver No 78 0.117 205 23 0.112 0
MMP16 MMP16 P51512 Matrix metalloproteinase-16 chr8 GO:0050790 Not Cancer Driver No 235 0.387 168 61 0.363 0
MMP17 MMP17 Q9ULZ9 Matrix metalloproteinase-17 chr12 GO:0050790 Not Cancer Driver No 93 0.154 241 26 0.108 0
MMP24 MMP24 Q9Y5R2 Matrix metalloproteinase-24 chr20 GO:0050790 Not Cancer Driver No 67 0.104 163 20 0.123 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0050790 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0050790 Not Cancer Driver No 23 0.074 64 2 0.031 0
MON1A MON1A Q86VX9 Vacuolar fusion protein MON1 homolog A chr3 GO:0050790 Not Cancer Driver No 54 0.083 260 14 0.054 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0050790 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0050790 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0050790 Census Yes 154 0.113 386 41 0.106 6
MST1 MST1 P26927 Hepatocyte growth factor-like protein chr3 GO:0050790 Not Cancer Driver No 110 0.155 168 19 0.113 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0050790 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTMR12 MTMR12 Q9C0I1 Myotubularin-related protein 12 chr5 GO:0050790 Not Cancer Driver No 105 0.141 130 16 0.123 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0050790 Not Cancer Driver No 60 0.109 45 7 0.156 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0050790 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 GO:0050790 Not Cancer Driver No 101 0.145 84 13 0.155 5
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0050790 Not Cancer Driver No 62 0.083 582 49 0.084 0
MVP MVP Q14764 Major vault protein chr16 GO:0050790 Not Cancer Driver No 141 0.158 285 31 0.109 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0050790 Not Cancer Driver No 608 0.13 1398 189 0.135 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0050790 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYO9B_ENST00000594824 MYO9B Q13459 Unconventional myosin-IXb chr19 GO:0050790 Not Cancer Driver No 226 0.105 827 80 0.097 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0050790 Not Cancer Driver No 284 0.303 853 263 0.308 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0050790 Census Yes 67 0.128 395 51 0.129 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0050790 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0050790 Not Cancer Driver No 61 0.123 386 44 0.114 0
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 GO:0050790 Not Cancer Driver No 113 0.099 72 8 0.111 3
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0050790 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0050790 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCF4_ENST00000248899 NCF4 Q15080 Neutrophil cytosol factor 4 chr22 GO:0050790 Not Cancer Driver No 60 0.177 27 4 0.148 1
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0050790 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0050790 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0050790 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 GO:0050790 Not Cancer Driver No 14 0.173 4 0 0.0 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0050790 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0050790 Not Cancer Driver No 41 0.105 165 14 0.085 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0050790 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0050790 Not Cancer Driver No 35 0.116 23 0 0.0 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0050790 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0050790 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0050790 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGEF NGEF Q8N5V2 Ephexin-1 chr2 GO:0050790 Not Cancer Driver No 125 0.176 296 34 0.115 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0050790 Not Cancer Driver No 35 0.117 83 8 0.096 2
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0050790 Not Cancer Driver No 60 0.124 21 3 0.143 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0050790 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0050790 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0050790 Not Cancer Driver No 300 0.306 71 20 0.282 9
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0050790 Not Cancer Driver No 139 0.335 5 1 0.2 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0050790 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0050790 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0050790 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0050790 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0050790 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0050790 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0050790 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOSIP NOSIP Q9Y314 Nitric oxide synthase-interacting protein chr19 GO:0050790 Not Cancer Driver No 37 0.123 159 21 0.132 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0050790 Not Cancer Driver No 123 0.213 0 0 0.0 0
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 GO:0050790 Not Cancer Driver No 27 0.057 215 14 0.065 0
NOXO1 NOXO1 Q8NFA2 NADPH oxidase organizer 1 chr16 GO:0050790 Not Cancer Driver No 29 0.077 182 9 0.049 0
NPFFR2 NPFFR2 Q9Y5X5 Neuropeptide FF receptor 2 chr4 GO:0050790 Not Cancer Driver No 154 0.295 57 20 0.351 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0050790 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0050790 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0050790 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPR3 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 GO:0050790 Not Cancer Driver No 95 0.176 58 8 0.138 0
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 GO:0050790 Not Cancer Driver No 45 0.079 158 22 0.139 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0050790 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0050790 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0050790 Not Cancer Driver No 66 0.159 101 1 0.01 5
NRBF2 NRBF2 Q96F24 Nuclear receptor-binding factor 2 chr10 GO:0050790 Not Cancer Driver No 34 0.118 224 25 0.112 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0050790 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0050790 Not Cancer Driver No 227 0.315 425 134 0.315 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0050790 Compendium Yes 146 0.158 211 31 0.147 0
NSMAF_ENST00000038176 NSMAF Q92636 Protein FAN chr8 GO:0050790 Not Cancer Driver No 118 0.129 80 13 0.163 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0050790 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0050790 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0050790 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUCB1 NUCB1 Q02818 Nucleobindin-1 chr19 GO:0050790 Not Cancer Driver No 56 0.121 352 43 0.122 0
NUCB2_ENST00000622082 NUCB2 P80303 Nucleobindin-2 chr11 GO:0050790 Not Cancer Driver No 49 0.117 265 40 0.151 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0050790 Not Cancer Driver No 10 0.122 82 10 0.122 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:0050790 Not Cancer Driver No 21 0.072 13 0 0.0 1
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0050790 Not Cancer Driver No 90 0.105 267 31 0.116 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0050790 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS2 OAS2 P29728 2'-5'-oligoadenylate synthase 2 chr12 GO:0050790 Not Cancer Driver No 141 0.196 47 14 0.298 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0050790 Not Cancer Driver No 139 0.128 147 17 0.116 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:0050790 Not Cancer Driver No 76 0.148 8 4 0.5 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 GO:0050790 Not Cancer Driver No 1208 0.152 2623 368 0.14 0
OPHN1 OPHN1 O60890 Oligophrenin-1 chrX GO:0050790 Not Cancer Driver No 122 0.152 302 42 0.139 0
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0050790 Not Cancer Driver No 26 0.086 101 9 0.089 5
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0050790 Not Cancer Driver No 22 0.144 9 1 0.111 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0050790 Not Cancer Driver No 105 0.118 401 37 0.092 0
OXA1L_ENST00000604262 OXA1L Q15070 Mitochondrial inner membrane protein OXA1L chr14 GO:0050790 Not Cancer Driver No 36 0.083 81 9 0.111 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0050790 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY13 P2RY13 Q9BPV8 P2Y purinoceptor 13 chr3 GO:0050790 Not Cancer Driver No 63 0.178 20 2 0.1 0
PABPN1 PABPN1 Q86U42 Polyadenylate-binding protein 2 chr14 GO:0050790 Not Cancer Driver No 27 0.088 241 18 0.075 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0050790 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0050790 Compendium Yes 89 0.17 242 49 0.202 0
PALM PALM O75781 Paralemmin-1 chr19 GO:0050790 Not Cancer Driver No 50 0.129 381 50 0.131 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0050790 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:0050790 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0050790 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0050790 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0050790 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP4 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 GO:0050790 Compendium Yes 218 0.126 325 40 0.123 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 GO:0050790 Not Cancer Driver No 100 0.137 605 86 0.142 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0050790 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0050790 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCP2 PCP2 Q8IVA1 Purkinje cell protein 2 homolog chr19 GO:0050790 Not Cancer Driver No 13 0.096 136 13 0.096 0
PCSK5 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 GO:0050790 Not Cancer Driver No 319 0.172 168 25 0.149 0
PCSK6 PCSK6 P29122 Proprotein convertase subtilisin/kexin type 6 chr15 GO:0050790 Not Cancer Driver No 138 0.142 207 45 0.217 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0050790 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0050790 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0050790 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0050790 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0050790 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 GO:0050790 Not Cancer Driver No 64 0.119 96 9 0.094 0
PDP2 PDP2 Q9P2J9 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial chr16 GO:0050790 Not Cancer Driver No 52 0.098 51 11 0.216 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0050790 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0050790 Not Cancer Driver No 58 0.102 199 19 0.095 0
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0050790 Not Cancer Driver No 28 0.145 0 0 0.0 1
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0050790 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0050790 Not Cancer Driver No 68 0.135 97 18 0.186 0
PGAM5 PGAM5 Q96HS1 Serine/threonine-protein phosphatase PGAM5, mitochondrial chr12 GO:0050790 Not Cancer Driver No 32 0.111 102 12 0.118 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0050790 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0050790 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHPT1 PHPT1 Q9NRX4 14 kDa phosphohistidine phosphatase chr9 GO:0050790 Not Cancer Driver No 13 0.104 6 0 0.0 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0050790 Not Cancer Driver No 83 0.11 419 45 0.107 2
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0050790 Census Yes 89 0.137 320 42 0.131 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0050790 Not Cancer Driver No 54 0.084 209 11 0.053 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0050790 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0050790 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0050790 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0050790 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0050790 Not Cancer Driver No 96 0.132 418 47 0.112 3
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0050790 Not Cancer Driver No 51 0.111 149 20 0.134 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0050790 Not Cancer Driver No 193 0.142 315 45 0.143 0
PIK3R5 PIK3R5 Q8WYR1 Phosphoinositide 3-kinase regulatory subunit 5 chr17 GO:0050790 Not Cancer Driver No 143 0.163 316 55 0.174 1
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0050790 Not Cancer Driver No 100 0.133 156 26 0.167 0
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0050790 Not Cancer Driver No 29 0.128 26 3 0.115 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0050790 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0050790 Not Cancer Driver No 57 0.098 99 13 0.131 23
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0050790 Not Cancer Driver No 66 0.201 328 66 0.201 0
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0050790 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0050790 Not Cancer Driver No 62 0.147 111 23 0.207 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0050790 Not Cancer Driver No 74 0.132 216 29 0.134 0
PITRM1_ENST00000224949 PITRM1 Q5JRX3 Presequence protease, mitochondrial chr10 GO:0050790 Not Cancer Driver No 122 0.118 220 26 0.118 2
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0050790 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0050790 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0050790 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0050790 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKIG_ENST00000372891 PKIG Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma chr20 GO:0050790 Not Cancer Driver No 15 0.197 76 15 0.197 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0050790 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0050790 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 GO:0050790 Not Cancer Driver No 78 0.098 150 14 0.093 2
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0050790 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0050790 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCD4_ENST00000417849 PLCD4 Q9BRC7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 chr2 GO:0050790 Not Cancer Driver No 78 0.102 90 5 0.056 0
PLEC PLEC Q15149 Plectin chr8 GO:0050790 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLEK PLEK P08567 Pleckstrin chr2 GO:0050790 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHG1 PLEKHG1 Q9ULL1 Pleckstrin homology domain-containing family G member 1 chr6 GO:0050790 Not Cancer Driver No 182 0.131 888 119 0.134 0
PLEKHG2 PLEKHG2 Q9H7P9 Pleckstrin homology domain-containing family G member 2 chr19 GO:0050790 Not Cancer Driver No 168 0.121 1053 139 0.132 1
PLEKHG3 PLEKHG3 A1L390 Pleckstrin homology domain-containing family G member 3 chr14 GO:0050790 Not Cancer Driver No 137 0.112 885 104 0.118 0
PLEKHG4 PLEKHG4 Q58EX7 Puratrophin-1 chr16 GO:0050790 Not Cancer Driver No 132 0.111 295 35 0.119 0
PLEKHG4B PLEKHG4B Q96PX9 Pleckstrin homology domain-containing family G member 4B chr5 GO:0050790 Not Cancer Driver No 234 0.184 704 107 0.152 0
PLEKHG5_ENST00000400913 PLEKHG5 O94827 Pleckstrin homology domain-containing family G member 5 chr1 GO:0050790 Not Cancer Driver No 93 0.092 537 54 0.101 3
PLEKHG6_ENST00000011684 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 GO:0050790 Not Cancer Driver No 103 0.13 471 65 0.138 0
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0050790 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0050790 Not Cancer Driver No 49 0.106 192 21 0.109 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0050790 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0050790 Not Cancer Driver No 43 0.135 92 13 0.141 0
PLXNB3_ENST00000361971 PLXNB3 Q9ULL4 Plexin-B3 chrX GO:0050790 Not Cancer Driver No 217 0.114 358 37 0.103 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0050790 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0050790 Not Cancer Driver No 124 0.267 32 11 0.344 1
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0050790 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0050790 Not Cancer Driver No 64 0.132 46 4 0.087 3
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0050790 Not Cancer Driver No 62 0.092 93 4 0.043 9
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0050790 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0050790 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0050790 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0050790 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0050790 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP1R11 PPP1R11 O60927 E3 ubiquitin-protein ligase PPP1R11 chr6 GO:0050790 Not Cancer Driver No 17 0.135 126 17 0.135 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0050790 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0050790 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0050790 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0050790 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R16A_ENST00000435887 PPP1R16A Q96I34 Protein phosphatase 1 regulatory subunit 16A chr8 GO:0050790 Not Cancer Driver No 56 0.106 308 26 0.084 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0050790 Not Cancer Driver No 132 0.233 220 66 0.3 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0050790 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:0050790 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3F PPP1R3F Q6ZSY5 Protein phosphatase 1 regulatory subunit 3F chrX GO:0050790 Not Cancer Driver No 79 0.099 636 64 0.101 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0050790 Not Cancer Driver No 14 0.039 198 11 0.056 0
PPP1R7 PPP1R7 Q15435 Protein phosphatase 1 regulatory subunit 7 chr2 GO:0050790 Not Cancer Driver No 46 0.128 78 16 0.205 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0050790 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0050790 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:0050790 Not Cancer Driver No 72 0.12 17 1 0.059 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 GO:0050790 Not Cancer Driver No 60 0.134 68 10 0.147 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 GO:0050790 Not Cancer Driver No 101 0.228 76 22 0.289 0
PPP2R2C_ENST00000382599 PPP2R2C Q9Y2T4 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform chr4 GO:0050790 Not Cancer Driver No 78 0.174 78 13 0.167 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 GO:0050790 Not Cancer Driver No 50 0.11 65 9 0.138 0
PPP2R3A PPP2R3A Q06190 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha chr3 GO:0050790 Not Cancer Driver No 136 0.118 513 66 0.129 0
PPP2R3B PPP2R3B Q9Y5P8 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta chrX GO:0050790 Not Cancer Driver No 72 0.125 154 15 0.097 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0050790 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:0050790 Not Cancer Driver No 79 0.159 119 9 0.076 0
PPP2R5C_ENST00000334743 PPP2R5C Q13362 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform chr14 GO:0050790 Not Cancer Driver No 65 0.124 89 16 0.18 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 GO:0050790 Not Cancer Driver No 64 0.106 178 13 0.073 4
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 GO:0050790 Not Cancer Driver No 68 0.146 86 20 0.233 0
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 GO:0050790 Not Cancer Driver No 19 0.112 1 0 0.0 0
PPP3R2 PPP3R2 Q96LZ3 Calcineurin subunit B type 2 chr9 GO:0050790 Not Cancer Driver No 61 0.359 12 5 0.417 0
PPP4R1 PPP4R1 Q8TF05 Serine/threonine-protein phosphatase 4 regulatory subunit 1 chr18 GO:0050790 Not Cancer Driver No 92 0.097 304 20 0.066 0
PPP4R2 PPP4R2 Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 chr3 GO:0050790 Not Cancer Driver No 32 0.077 314 26 0.083 0
PPP4R4 PPP4R4 Q6NUP7 Serine/threonine-protein phosphatase 4 regulatory subunit 4 chr14 GO:0050790 Not Cancer Driver No 164 0.188 209 43 0.206 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0050790 Not Cancer Driver No 37 0.121 0 0 0.0 23
PREB PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 GO:0050790 Not Cancer Driver No 56 0.134 91 10 0.11 0
PREX2 PREX2 Q70Z35 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein chr8 GO:0050790 Census, Compendium Yes 492 0.306 234 68 0.291 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0050790 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 GO:0050790 Not Cancer Driver No 39 0.144 124 13 0.105 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 GO:0050790 Not Cancer Driver No 31 0.114 110 12 0.109 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0050790 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0050790 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:0050790 Not Cancer Driver No 74 0.151 144 25 0.174 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0050790 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0050790 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:0050790 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0050790 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0050790 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0050790 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0050790 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0050790 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0050790 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0050790 Compendium Yes 118 0.134 246 34 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0050790 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0050790 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRLR PRLR P16471 Prolactin receptor chr5 GO:0050790 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRNP PRNP P04156 Major prion protein chr20 GO:0050790 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0050790 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0050790 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0050790 Not Cancer Driver No 42 0.094 235 24 0.102 0
PSAP PSAP P07602 Prosaposin chr10 GO:0050790 Not Cancer Driver No 59 0.113 28 2 0.071 8
PSD PSD A5PKW4 PH and SEC7 domain-containing protein 1 chr10 GO:0050790 Not Cancer Driver No 173 0.169 714 130 0.182 0
PSD2 PSD2 Q9BQI7 PH and SEC7 domain-containing protein 2 chr5 GO:0050790 Not Cancer Driver No 155 0.201 398 87 0.219 0
PSD3_ENST00000440756 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 GO:0050790 Not Cancer Driver No 146 0.139 645 94 0.146 0
PSD4 PSD4 Q8NDX1 PH and SEC7 domain-containing protein 4 chr2 GO:0050790 Not Cancer Driver No 157 0.149 739 103 0.139 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0050790 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMC3IP PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:0050790 Not Cancer Driver No 25 0.115 73 8 0.11 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 GO:0050790 Not Cancer Driver No 110 0.115 201 19 0.095 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0050790 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 GO:0050790 Not Cancer Driver No 100 0.11 135 14 0.104 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 GO:0050790 Not Cancer Driver No 69 0.129 152 19 0.125 0
PSMD6_ENST00000295901 PSMD6 Q15008 26S proteasome non-ATPase regulatory subunit 6 chr3 GO:0050790 Not Cancer Driver No 33 0.085 40 3 0.075 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0050790 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0050790 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0050790 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTGIR PTGIR P43119 Prostacyclin receptor chr19 GO:0050790 Not Cancer Driver No 40 0.104 47 4 0.085 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0050790 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0050790 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0050790 Census Yes 42 0.093 12 0 0.0 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0050790 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0050790 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0050790 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0050790 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0050790 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 GO:0050790 Not Cancer Driver No 39 0.102 74 2 0.027 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0050790 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB3IL1 RAB3IL1 Q8TBN0 Guanine nucleotide exchange factor for Rab-3A chr11 GO:0050790 Not Cancer Driver No 41 0.107 217 18 0.083 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 GO:0050790 Not Cancer Driver No 85 0.179 227 33 0.145 0
RABEP1 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 GO:0050790 Census, Compendium Yes 81 0.094 520 57 0.11 0
RABEP2 RABEP2 Q9H5N1 Rab GTPase-binding effector protein 2 chr16 GO:0050790 Not Cancer Driver No 87 0.153 441 71 0.161 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 GO:0050790 Not Cancer Driver No 114 0.107 407 40 0.098 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 GO:0050790 Not Cancer Driver No 116 0.142 235 33 0.14 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0050790 Not Cancer Driver No 73 0.149 175 35 0.2 0
RABIF RABIF P47224 Guanine nucleotide exchange factor MSS4 chr1 GO:0050790 Not Cancer Driver No 10 0.081 25 3 0.12 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0050790 Not Cancer Driver No 31 0.161 0 0 0.0 2
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 GO:0050790 Not Cancer Driver No 74 0.117 255 27 0.106 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0050790 Not Cancer Driver No 34 0.107 13 0 0.0 0
RALGAPA1_ENST00000389698 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 GO:0050790 Not Cancer Driver No 227 0.111 649 73 0.112 1
RALGAPA2 RALGAPA2 Q2PPJ7 Ral GTPase-activating protein subunit alpha-2 chr20 GO:0050790 Not Cancer Driver No 243 0.13 415 66 0.159 0
RALGAPB_ENST00000397040 RALGAPB Q86X10 Ral GTPase-activating protein subunit beta chr20 GO:0050790 Not Cancer Driver No 202 0.135 376 54 0.144 0
RALGDS RALGDS Q12967 Ral guanine nucleotide dissociation stimulator chr9 GO:0050790 Census, Compendium Yes 104 0.114 379 44 0.116 0
RALGPS1 RALGPS1 Q5JS13 Ras-specific guanine nucleotide-releasing factor RalGPS1 chr9 GO:0050790 Not Cancer Driver No 62 0.111 219 26 0.119 0
RALGPS2 RALGPS2 Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 chr1 GO:0050790 Not Cancer Driver No 83 0.142 183 23 0.126 0
RAMAC RAMAC Q9BTL3 RNA guanine-N7 methyltransferase activating subunit chr15 GO:0050790 Not Cancer Driver No 14 0.119 118 14 0.119 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 GO:0050790 Not Cancer Driver No 19 0.095 137 16 0.117 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0050790 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RANBP3 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 GO:0050790 Not Cancer Driver No 71 0.125 468 54 0.115 0
RANBP3L_ENST00000296604 RANBP3L Q86VV4 Ran-binding protein 3-like chr5 GO:0050790 Not Cancer Driver No 71 0.153 185 33 0.178 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0050790 Not Cancer Driver No 65 0.111 159 17 0.107 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0050790 Not Cancer Driver No 10 0.054 42 5 0.119 0
RAP1GAP2 RAP1GAP2 Q684P5 Rap1 GTPase-activating protein 2 chr17 GO:0050790 Not Cancer Driver No 93 0.127 413 57 0.138 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0050790 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0050790 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0050790 Not Cancer Driver No 32 0.175 8 2 0.25 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0050790 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF4 RAPGEF4 Q8WZA2 Rap guanine nucleotide exchange factor 4 chr2 GO:0050790 Not Cancer Driver No 149 0.147 191 29 0.152 0
RAPGEF5_ENST00000401957 RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 chr7 GO:0050790 Not Cancer Driver No 73 0.126 56 10 0.179 0
RAPGEFL1_ENST00000620260 RAPGEFL1 Q9UHV5 Rap guanine nucleotide exchange factor-like 1 chr17 GO:0050790 Not Cancer Driver No 49 0.074 200 3 0.015 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0050790 Not Cancer Driver No 25 0.152 7 1 0.143 0
RASA4 RASA4 O43374 Ras GTPase-activating protein 4 chr7 GO:0050790 Not Cancer Driver No 14 0.017 164 3 0.018 0
RASGEF1A_ENST00000395810 RASGEF1A Q8N9B8 Ras-GEF domain-containing family member 1A chr10 GO:0050790 Not Cancer Driver No 69 0.143 66 11 0.167 0
RASGEF1B RASGEF1B Q0VAM2 Ras-GEF domain-containing family member 1B chr4 GO:0050790 Not Cancer Driver No 66 0.14 27 6 0.222 0
RASGEF1C RASGEF1C Q8N431 Ras-GEF domain-containing family member 1C chr5 GO:0050790 Not Cancer Driver No 80 0.172 62 9 0.145 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0050790 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRF2 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 GO:0050790 Not Cancer Driver No 216 0.175 274 55 0.201 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0050790 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0050790 Not Cancer Driver No 73 0.076 505 48 0.095 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0050790 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 GO:0050790 Not Cancer Driver No 140 0.131 335 41 0.122 0
RBL2 RBL2 Q08999 Retinoblastoma-like protein 2 chr16 GO:0050790 Not Cancer Driver No 116 0.102 504 56 0.111 0
RCAN2_ENST00000330430 RCAN2 Q14206 Calcipressin-2 chr6 GO:0050790 Not Cancer Driver No 43 0.218 92 20 0.217 0
RCAN3_ENST00000538532 RCAN3 Q9UKA8 Calcipressin-3 chr1 GO:0050790 Not Cancer Driver No 34 0.141 121 18 0.149 0
RCBTB2_ENST00000344532 RCBTB2 O95199 RCC1 and BTB domain-containing protein 2 chr13 GO:0050790 Not Cancer Driver No 86 0.156 36 3 0.083 0
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0050790 Not Cancer Driver No 19 0.041 87 7 0.08 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 GO:0050790 Not Cancer Driver No 54 0.128 143 15 0.105 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0050790 Not Cancer Driver No 63 0.121 194 27 0.139 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0050790 Not Cancer Driver No 37 0.185 24 5 0.208 0
RD3 RD3 Q7Z3Z2 Protein RD3 chr1 GO:0050790 Not Cancer Driver No 46 0.236 75 21 0.28 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0050790 Not Cancer Driver No 71 0.122 297 37 0.125 1
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0050790 Not Cancer Driver No 115 0.118 9 2 0.222 0
RELN RELN P78509 Reelin chr7 GO:0050790 Not Cancer Driver No 761 0.22 107 19 0.178 7
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0050790 Not Cancer Driver No 147 0.128 674 82 0.122 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0050790 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0050790 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0050790 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0050790 Not Cancer Driver No 38 0.112 20 1 0.05 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0050790 Not Cancer Driver No 50 0.138 150 21 0.14 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0050790 Not Cancer Driver No 15 0.097 1 0 0.0 0
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0050790 Not Cancer Driver No 73 0.23 28 5 0.179 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0050790 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGL1_ENST00000360851 RGL1 Q9NZL6 Ral guanine nucleotide dissociation stimulator-like 1 chr1 GO:0050790 Not Cancer Driver No 106 0.138 295 41 0.139 0
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0050790 Not Cancer Driver No 87 0.112 461 51 0.111 0
RGL4 RGL4 Q8IZJ4 Ral-GDS-related protein chr22 GO:0050790 Not Cancer Driver No 51 0.108 175 18 0.103 0
RGN RGN Q15493 Regucalcin chrX GO:0050790 Not Cancer Driver No 38 0.127 14 3 0.214 0
RGPD1 RGPD1 P0DJD0 RANBP2-like and GRIP domain-containing protein 1 chr2 GO:0050790 Not Cancer Driver No 31 0.018 634 10 0.016 0
RGPD2 RGPD2 P0DJD1 RANBP2-like and GRIP domain-containing protein 2 chr2 GO:0050790 Not Cancer Driver No 50 0.028 633 13 0.021 0
RGPD3 RGPD3 A6NKT7 RanBP2-like and GRIP domain-containing protein 3 chr2 GO:0050790 Census, Compendium Yes 339 0.193 605 195 0.322 0
RGPD4 RGPD4 Q7Z3J3 RanBP2-like and GRIP domain-containing protein 4 chr2 GO:0050790 Not Cancer Driver No 379 0.216 661 161 0.244 0
RGPD8 RGPD8 O14715 RANBP2-like and GRIP domain-containing protein 8 chr2 GO:0050790 Not Cancer Driver No 129 0.073 621 71 0.114 0
RGS11 RGS11 O94810 Regulator of G-protein signaling 11 chr16 GO:0050790 Not Cancer Driver No 43 0.092 81 2 0.025 0
RGS12 RGS12 O14924 Regulator of G-protein signaling 12 chr4 GO:0050790 Not Cancer Driver No 208 0.144 835 129 0.154 0
RGS17 RGS17 Q9UGC6 Regulator of G-protein signaling 17 chr6 GO:0050790 Not Cancer Driver No 45 0.214 48 11 0.229 0
RGS18 RGS18 Q9NS28 Regulator of G-protein signaling 18 chr1 GO:0050790 Not Cancer Driver No 69 0.294 58 25 0.431 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0050790 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS20 RGS20 O76081 Regulator of G-protein signaling 20 chr8 GO:0050790 Not Cancer Driver No 59 0.152 194 36 0.186 0
RGS3 RGS3 P49796 Regulator of G-protein signaling 3 chr9 GO:0050790 Not Cancer Driver No 157 0.131 619 82 0.132 0
RGS5_ENST00000313961 RGS5 O15539 Regulator of G-protein signaling 5 chr1 GO:0050790 Not Cancer Driver No 45 0.249 21 5 0.238 0
RGS9 RGS9 O75916 Regulator of G-protein signaling 9 chr17 GO:0050790 Not Cancer Driver No 138 0.205 240 65 0.271 1
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 GO:0050790 Not Cancer Driver No 20 0.095 10 0 0.0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 GO:0050790 Not Cancer Driver No 18 0.085 10 0 0.0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 GO:0050790 Not Cancer Driver No 26 0.136 22 5 0.227 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 GO:0050790 Not Cancer Driver No 34 0.132 63 6 0.095 0
RIC8A_ENST00000526104 RIC8A Q9NPQ8 Synembryn-A chr11 GO:0050790 Not Cancer Driver No 63 0.119 163 23 0.141 0
RIC8B_ENST00000392839 RIC8B Q9NVN3 Synembryn-B chr12 GO:0050790 Not Cancer Driver No 58 0.112 117 20 0.171 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0050790 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIN1 RIN1 Q13671 Ras and Rab interactor 1 chr11 GO:0050790 Not Cancer Driver No 76 0.097 376 43 0.114 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0050790 Not Cancer Driver No 137 0.139 417 61 0.146 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 GO:0050790 Not Cancer Driver No 60 0.148 302 44 0.146 0
RINL RINL Q6ZS11 Ras and Rab interactor-like protein chr19 GO:0050790 Not Cancer Driver No 50 0.088 367 32 0.087 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0050790 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0050790 Not Cancer Driver No 66 0.127 295 39 0.132 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0050790 Not Cancer Driver No 131 0.123 421 76 0.181 0
RLN2 RLN2 P04090 Prorelaxin H2 chr9 GO:0050790 Not Cancer Driver No 31 0.168 39 4 0.103 0
RNF180 RNF180 Q86T96 E3 ubiquitin-protein ligase RNF180 chr5 GO:0050790 Not Cancer Driver No 80 0.135 190 26 0.137 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0050790 Not Cancer Driver No 30 0.081 112 7 0.062 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0050790 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0050790 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0050790 Not Cancer Driver No 203 0.215 299 71 0.237 5
RP2 RP2 O75695 Protein XRP2 chrX GO:0050790 Not Cancer Driver No 45 0.129 28 6 0.214 10
RPGR_ENST00000339363 RPGR Q92834 X-linked retinitis pigmentosa GTPase regulator chrX GO:0050790 Not Cancer Driver No 115 0.113 639 64 0.1 25
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 GO:0050790 Not Cancer Driver No 27 0.152 12 1 0.083 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0050790 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL37 RPL37 P61927 60S ribosomal protein L37 chr5 GO:0050790 Not Cancer Driver No 12 0.124 83 10 0.12 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:0050790 Census Yes 57 0.192 96 17 0.177 2
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:0050790 Not Cancer Driver No 13 0.09 59 7 0.119 0
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 GO:0050790 Not Cancer Driver No 34 0.116 85 14 0.165 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 GO:0050790 Not Cancer Driver No 18 0.151 53 8 0.151 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0050790 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0050790 Not Cancer Driver No 29 0.149 39 7 0.179 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 GO:0050790 Not Cancer Driver No 74 0.098 513 48 0.094 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0050790 Not Cancer Driver No 147 0.151 403 57 0.141 0
RUNDC1 RUNDC1 Q96C34 RUN domain-containing protein 1 chr17 GO:0050790 Not Cancer Driver No 65 0.106 238 21 0.088 0
RUNDC3A RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 GO:0050790 Not Cancer Driver No 39 0.087 175 8 0.046 0
S100A1 S100A1 P23297 Protein S100-A1 chr1 GO:0050790 Not Cancer Driver No 13 0.138 9 0 0.0 0
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 GO:0050790 Not Cancer Driver No 39 0.113 90 6 0.067 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0050790 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0050790 Not Cancer Driver No 53 0.096 6 1 0.167 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 GO:0050790 Not Cancer Driver No 61 0.128 13 3 0.231 1
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0050790 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SDHAF4 SDHAF4 Q5VUM1 Succinate dehydrogenase assembly factor 4, mitochondrial chr6 GO:0050790 Not Cancer Driver No 14 0.13 76 10 0.132 0
SEC23A SEC23A Q15436 Protein transport protein Sec23A chr14 GO:0050790 Not Cancer Driver No 100 0.131 73 8 0.11 1
SEC23B SEC23B Q15437 Protein transport protein Sec23B chr20 GO:0050790 Not Cancer Driver No 105 0.137 82 4 0.049 7
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0050790 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0050790 Not Cancer Driver No 101 0.219 442 98 0.222 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0050790 Not Cancer Driver No 147 0.253 561 145 0.258 0
SERGEF SERGEF Q9UGK8 Secretion-regulating guanine nucleotide exchange factor chr11 GO:0050790 Not Cancer Driver No 49 0.107 91 7 0.077 0
SERINC1 SERINC1 Q9NRX5 Serine incorporator 1 chr6 GO:0050790 Not Cancer Driver No 51 0.113 21 1 0.048 0
SERINC5_ENST00000509193 SERINC5 Q86VE9 Serine incorporator 5 chr5 GO:0050790 Not Cancer Driver No 38 0.09 13 1 0.077 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0050790 Not Cancer Driver No 142 0.364 47 28 0.596 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0050790 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0050790 Not Cancer Driver No 62 0.091 154 12 0.078 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0050790 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0050790 Not Cancer Driver No 47 0.159 1 0 0.0 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0050790 Census, Compendium Yes 58 0.135 86 16 0.186 0
SGSM1 SGSM1 Q2NKQ1 Small G protein signaling modulator 1 chr22 GO:0050790 Not Cancer Driver No 206 0.179 418 68 0.163 0
SGSM2_ENST00000426855 SGSM2 O43147 Small G protein signaling modulator 2 chr17 GO:0050790 Not Cancer Driver No 83 0.083 316 21 0.066 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0050790 Not Cancer Driver No 83 0.111 77 9 0.117 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0050790 Not Cancer Driver No 68 0.118 305 40 0.131 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0050790 Not Cancer Driver No 110 0.128 440 72 0.164 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0050790 Not Cancer Driver No 143 0.148 241 43 0.178 0
SH3BP5 SH3BP5 O60239 SH3 domain-binding protein 5 chr3 GO:0050790 Not Cancer Driver No 46 0.101 378 35 0.093 0
SH3BP5L SH3BP5L Q7L8J4 SH3 domain-binding protein 5-like chr1 GO:0050790 Not Cancer Driver No 62 0.158 376 57 0.152 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 GO:0050790 Not Cancer Driver No 141 0.124 797 101 0.127 0
SH3PXD2B SH3PXD2B A1X283 SH3 and PX domain-containing protein 2B chr5 GO:0050790 Not Cancer Driver No 122 0.134 660 101 0.153 1
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0050790 Not Cancer Driver No 84 0.144 397 58 0.146 0
SHOC2 SHOC2 Q9UQ13 Leucine-rich repeat protein SHOC-2 chr10 GO:0050790 Not Cancer Driver No 55 0.095 110 12 0.109 2
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 GO:0050790 Not Cancer Driver No 321 0.178 1175 226 0.192 0
SIPA1L2 SIPA1L2 Q9P2F8 Signal-induced proliferation-associated 1-like protein 2 chr1 GO:0050790 Not Cancer Driver No 311 0.181 895 172 0.192 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 GO:0050790 Not Cancer Driver No 273 0.153 1257 190 0.151 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0050790 Not Cancer Driver No 67 0.064 666 43 0.065 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0050790 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0050790 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0050790 Not Cancer Driver No 33 0.083 60 2 0.033 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0050790 Not Cancer Driver No 46 0.146 4 0 0.0 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:0050790 Not Cancer Driver No 19 0.117 95 17 0.179 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0050790 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0050790 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0050790 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0050790 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC27A4 SLC27A4 Q6P1M0 Long-chain fatty acid transport protein 4 chr9 GO:0050790 Not Cancer Driver No 83 0.129 27 3 0.111 5
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0050790 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0050790 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 GO:0050790 Not Cancer Driver No 153 0.168 130 23 0.177 39
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0050790 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0050790 Not Cancer Driver No 263 0.284 152 35 0.23 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0050790 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0050790 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0050790 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 GO:0050790 Not Cancer Driver No 54 0.116 352 46 0.131 0
SMAP2 SMAP2 Q8WU79 Stromal membrane-associated protein 2 chr1 GO:0050790 Not Cancer Driver No 50 0.117 214 30 0.14 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0050790 Not Cancer Driver No 166 0.117 751 97 0.129 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0050790 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0050790 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0050790 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0050790 Not Cancer Driver No 32 0.162 61 2 0.033 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0050790 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS4_ENST00000555846 SOCS4 Q8WXH5 Suppressor of cytokine signaling 4 chr14 GO:0050790 Not Cancer Driver No 43 0.098 136 13 0.096 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0050790 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 GO:0050790 Not Cancer Driver No 81 0.151 299 48 0.161 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0050790 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0050790 Not Cancer Driver No 374 0.169 87 10 0.115 0
SORT1 SORT1 Q99523 Sortilin chr1 GO:0050790 Not Cancer Driver No 69 0.083 110 2 0.018 0
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0050790 Not Cancer Driver No 173 0.13 362 54 0.149 2
SPATA13_ENST00000382095 SPATA13 Q96N96 Spermatogenesis-associated protein 13 chr13 GO:0050790 Not Cancer Driver No 68 0.104 263 32 0.122 0
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0050790 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0050790 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0050790 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0050790 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPINK2_ENST00000248701 SPINK2 P20155 Serine protease inhibitor Kazal-type 2 chr4 GO:0050790 Not Cancer Driver No 10 0.119 0 0 0.0 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0050790 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPINK6_ENST00000621437 SPINK6 Q6UWN8 Serine protease inhibitor Kazal-type 6 chr5 GO:0050790 Not Cancer Driver No 17 0.212 0 0 0.0 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0050790 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0050790 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPTSSB_ENST00000620149 SPTSSB Q8NFR3 Serine palmitoyltransferase small subunit B chr3 GO:0050790 Not Cancer Driver No 15 0.197 0 0 0.0 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0050790 Census Yes 53 0.099 130 11 0.085 1
SRGAP1 SRGAP1 Q7Z6B7 SLIT-ROBO Rho GTPase-activating protein 1 chr12 GO:0050790 Not Cancer Driver No 191 0.176 553 87 0.157 4
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 GO:0050790 Census, Compendium Yes 195 0.177 549 97 0.177 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:0050790 Not Cancer Driver No 27 0.182 0 0 0.0 6
ST18 ST18 O60284 Suppression of tumorigenicity 18 protein chr8 GO:0050790 Not Cancer Driver No 330 0.315 820 282 0.344 0
ST5 DENND2B P78524 DENN domain-containing protein 2B chr11 GO:0050790 Not Cancer Driver No 144 0.127 671 93 0.139 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0050790 Not Cancer Driver No 66 0.224 103 18 0.175 0
STARD13 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 GO:0050790 Not Cancer Driver No 177 0.159 494 78 0.158 0
STARD8_ENST00000374597 STARD8 Q92502 StAR-related lipid transfer protein 8 chrX GO:0050790 Not Cancer Driver No 145 0.142 574 86 0.15 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0050790 Census, Compendium Yes 110 0.143 152 15 0.099 19
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 GO:0050790 Not Cancer Driver No 70 0.102 387 45 0.116 13
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0050790 Not Cancer Driver No 15 0.101 149 15 0.101 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0050790 Not Cancer Driver No 121 0.122 659 83 0.126 2
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0050790 Not Cancer Driver No 35 0.116 112 14 0.125 12
STXBP5 STXBP5 Q5T5C0 Syntaxin-binding protein 5 chr6 GO:0050790 Not Cancer Driver No 128 0.111 344 46 0.134 0
STXBP5L STXBP5L Q9Y2K9 Syntaxin-binding protein 5-like chr3 GO:0050790 Not Cancer Driver No 358 0.302 292 101 0.346 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0050790 Not Cancer Driver No 55 0.176 18 3 0.167 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 GO:0050790 Census, Compendium Yes 83 0.112 483 46 0.095 3
SVBP_ENST00000372522 SVBP Q8N300 Small vasohibin-binding protein chr1 GO:0050790 Not Cancer Driver No 7 0.106 66 7 0.106 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0050790 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 GO:0050790 Not Cancer Driver No 62 0.084 412 27 0.066 0
SYDE2 SYDE2 Q5VT97 Rho GTPase-activating protein SYDE2 chr1 GO:0050790 Not Cancer Driver No 136 0.114 693 69 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0050790 Census Yes 96 0.151 131 27 0.206 5
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0050790 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 GO:0050790 Not Cancer Driver No 21 0.071 111 2 0.018 0
TAGAP TAGAP Q8N103 T-cell activation Rho GTPase-activating protein chr6 GO:0050790 Not Cancer Driver No 114 0.156 457 76 0.166 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0050790 Census Yes 54 0.163 305 53 0.174 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0050790 Not Cancer Driver No 42 0.099 302 26 0.086 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0050790 Not Cancer Driver No 123 0.137 494 64 0.13 0
TAX1BP3 TAX1BP3 O14907 Tax1-binding protein 3 chr17 GO:0050790 Not Cancer Driver No 16 0.129 51 8 0.157 0
TBC1D1 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 GO:0050790 Not Cancer Driver No 138 0.118 455 58 0.127 0
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0050790 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBC1D10B TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 GO:0050790 Not Cancer Driver No 54 0.067 498 27 0.054 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0050790 Not Cancer Driver No 58 0.13 192 32 0.167 0
TBC1D12 TBC1D12 O60347 TBC1 domain family member 12 chr10 GO:0050790 Not Cancer Driver No 62 0.08 458 20 0.044 0
TBC1D13 TBC1D13 Q9NVG8 TBC1 domain family member 13 chr9 GO:0050790 Not Cancer Driver No 49 0.122 57 10 0.175 0
TBC1D14 TBC1D14 Q9P2M4 TBC1 domain family member 14 chr4 GO:0050790 Not Cancer Driver No 80 0.115 311 36 0.116 0
TBC1D15 TBC1D15 Q8TC07 TBC1 domain family member 15 chr12 GO:0050790 Not Cancer Driver No 90 0.13 135 23 0.17 0
TBC1D16 TBC1D16 Q8TBP0 TBC1 domain family member 16 chr17 GO:0050790 Not Cancer Driver No 84 0.11 307 37 0.121 0
TBC1D17 TBC1D17 Q9HA65 TBC1 domain family member 17 chr19 GO:0050790 Not Cancer Driver No 76 0.117 191 25 0.131 0
TBC1D19 TBC1D19 Q8N5T2 TBC1 domain family member 19 chr4 GO:0050790 Not Cancer Driver No 69 0.131 25 1 0.04 0
TBC1D2 TBC1D2 Q9BYX2 TBC1 domain family member 2A chr9 GO:0050790 Not Cancer Driver No 106 0.114 338 39 0.115 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 GO:0050790 Not Cancer Driver No 62 0.185 7 0 0.0 0
TBC1D22A TBC1D22A Q8WUA7 TBC1 domain family member 22A chr22 GO:0050790 Not Cancer Driver No 84 0.162 219 23 0.105 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 GO:0050790 Not Cancer Driver No 55 0.109 205 27 0.132 0
TBC1D24_ENST00000293970 TBC1D24 Q9ULP9 TBC1 domain family member 24 chr16 GO:0050790 Not Cancer Driver No 59 0.106 33 2 0.061 16
TBC1D25 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX GO:0050790 Not Cancer Driver No 114 0.166 256 37 0.145 0
TBC1D26 TBC1D26 Q86UD7 TBC1 domain family member 26 chr17 GO:0050790 Not Cancer Driver No 34 0.136 66 7 0.106 0
TBC1D28 TBC1D28 Q2M2D7 TBC1 domain family member 28 chr17 GO:0050790 Not Cancer Driver No 36 0.171 61 12 0.197 0
TBC1D2B TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 GO:0050790 Not Cancer Driver No 118 0.123 419 43 0.103 0
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 GO:0050790 Not Cancer Driver No 173 0.133 590 90 0.153 0
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0050790 Not Cancer Driver No 117 0.147 358 58 0.162 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0050790 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBC1D8B TBC1D8B Q0IIM8 TBC1 domain family member 8B chrX GO:0050790 Not Cancer Driver No 197 0.176 134 21 0.157 2
TBC1D8_ENST00000376840 TBC1D8 O95759 TBC1 domain family member 8 chr2 GO:0050790 Not Cancer Driver No 164 0.144 224 28 0.125 0
TBC1D9 TBC1D9 Q6ZT07 TBC1 domain family member 9 chr4 GO:0050790 Not Cancer Driver No 196 0.155 295 57 0.193 0
TBC1D9B TBC1D9B Q66K14 TBC1 domain family member 9B chr5 GO:0050790 Not Cancer Driver No 142 0.114 346 34 0.098 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0050790 Not Cancer Driver No 156 0.131 60 9 0.15 11
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0050790 Not Cancer Driver No 115 0.129 88 9 0.102 2
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0050790 Not Cancer Driver No 47 0.137 17 4 0.235 1
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0050790 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0050790 Not Cancer Driver No 54 0.097 55 10 0.182 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0050790 Not Cancer Driver No 75 0.183 185 31 0.168 0
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0050790 Not Cancer Driver No 37 0.103 26 5 0.192 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0050790 Not Cancer Driver No 219 0.195 126 22 0.175 10
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0050790 Not Cancer Driver No 6 0.049 8 4 0.5 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0050790 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0050790 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0050790 Census Yes 110 0.097 212 16 0.075 31
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0050790 Not Cancer Driver No 63 0.101 339 35 0.103 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0050790 Compendium Yes 61 0.18 285 52 0.182 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0050790 Not Cancer Driver No 87 0.104 331 39 0.118 0
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0050790 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0050790 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0050790 Not Cancer Driver No 63 0.152 47 8 0.17 3
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0050790 Not Cancer Driver No 32 0.107 22 2 0.091 1
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0050790 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0050790 Not Cancer Driver No 370 0.233 810 194 0.24 0
TIAM2 TIAM2 Q8IVF5 Rho guanine nucleotide exchange factor TIAM2 chr6 GO:0050790 Not Cancer Driver No 309 0.182 779 166 0.213 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0050790 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0050790 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0050790 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0050790 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIPRL TIPRL O75663 TIP41-like protein chr1 GO:0050790 Not Cancer Driver No 25 0.092 25 3 0.12 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0050790 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0050790 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0050790 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0050790 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0050790 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 GO:0050790 Not Cancer Driver No 24 0.11 15 3 0.2 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0050790 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0050790 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0050790 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0050790 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFAIP8L3 TNFAIP8L3 Q5GJ75 Tumor necrosis factor alpha-induced protein 8-like protein 3 chr15 GO:0050790 Not Cancer Driver No 40 0.137 111 12 0.108 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0050790 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0050790 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0050790 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0050790 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0050790 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNXB_ENST00000375244 TNXB P22105 Tenascin-X chr6 GO:0050790 Not Cancer Driver No 666 0.157 2794 498 0.178 5
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0050790 Not Cancer Driver No 149 0.143 795 105 0.132 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0050790 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0050790 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0050790 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0050790 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0050790 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0050790 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM23 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 GO:0050790 Not Cancer Driver No 91 0.159 39 2 0.051 0
TRIO TRIO O75962 Triple functional domain protein chr5 GO:0050790 Not Cancer Driver No 400 0.129 1052 118 0.112 10
TSC1 TSC1 Q92574 Hamartin chr9 GO:0050790 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0050790 Not Cancer Driver No 46 0.118 159 23 0.145 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0050790 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTC8_ENST00000338104 TTC8 Q8TAM2 Tetratricopeptide repeat protein 8 chr14 GO:0050790 Not Cancer Driver No 74 0.137 98 12 0.122 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 GO:0050790 Not Cancer Driver No 7917 0.23 12926 2861 0.221 10
TXN TXN P10599 Thioredoxin chr9 GO:0050790 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0050790 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0050790 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0050790 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0050790 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0050790 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0050790 Not Cancer Driver No 35 0.118 271 33 0.122 0
UCN UCN P55089 Urocortin chr2 GO:0050790 Not Cancer Driver No 7 0.056 61 4 0.066 0
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0050790 Not Cancer Driver No 97 0.122 353 49 0.139 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0050790 Not Cancer Driver No 20 0.083 89 4 0.045 1
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0050790 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP44_ENST00000537435 USP44 Q9H0E7 Ubiquitin carboxyl-terminal hydrolase 44 chr12 GO:0050790 Census, Compendium Yes 94 0.132 114 14 0.123 0
USP6 USP6 P35125 Ubiquitin carboxyl-terminal hydrolase 6 chr17 GO:0050790 Census, Compendium Yes 243 0.173 537 83 0.155 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 GO:0050790 Not Cancer Driver No 113 0.136 472 81 0.172 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0050790 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0050790 Not Cancer Driver No 153 0.181 102 18 0.176 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0050790 Not Cancer Driver No 88 0.109 186 16 0.086 16
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0050790 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0050790 Not Cancer Driver No 27 0.116 41 7 0.171 0
VPS25 VPS25 Q9BRG1 Vacuolar protein-sorting-associated protein 25 chr17 GO:0050790 Not Cancer Driver No 16 0.091 10 0 0.0 0
VPS9D1 VPS9D1 Q9Y2B5 VPS9 domain-containing protein 1 chr16 GO:0050790 Not Cancer Driver No 57 0.09 353 26 0.074 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0050790 Not Cancer Driver No 65 0.137 180 18 0.1 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0050790 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0050790 Not Cancer Driver No 6 0.013 336 6 0.018 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0050790 Not Cancer Driver No 72 0.143 394 57 0.145 0
WDR81 WDR81 Q562E7 WD repeat-containing protein 81 chr17 GO:0050790 Not Cancer Driver No 164 0.084 721 51 0.071 1
WDR91 WDR91 A4D1P6 WD repeat-containing protein 91 chr7 GO:0050790 Not Cancer Driver No 99 0.133 206 38 0.184 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0050790 Not Cancer Driver No 104 0.183 345 65 0.188 1
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0050790 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0050790 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0050790 Not Cancer Driver No 66 0.174 0 0 0.0 2
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0050790 Not Cancer Driver No 66 0.12 232 29 0.125 4
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 GO:0050790 Not Cancer Driver No 50 0.075 292 7 0.024 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0050790 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0050790 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0050790 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0050790 Not Cancer Driver No 87 0.119 118 11 0.093 0
ZDHHC21 ZDHHC21 Q8IVQ6 Palmitoyltransferase ZDHHC21 chr9 GO:0050790 Not Cancer Driver No 34 0.128 0 0 0.0 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0050790 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0050790 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0050790 Not Cancer Driver No 85 0.149 383 55 0.144 0
ZFYVE28 ZFYVE28 Q9HCC9 Lateral signaling target protein 2 homolog chr4 GO:0050790 Not Cancer Driver No 132 0.149 420 67 0.16 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 GO:0050790 Not Cancer Driver No 75 0.141 346 49 0.142 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0050790 Not Cancer Driver No 114 0.201 91 19 0.209 0