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Total number of protein in "GO:0045595" GO term:  1291

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAMDC_ENST00000526415 AAMDC Q9H7C9 Mth938 domain-containing protein chr11 GO:0045595 Not Cancer Driver No 13 0.107 47 5 0.106 0
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0045595 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0045595 Not Cancer Driver No 511 0.197 136 23 0.169 14
ABCA5 ABCA5 Q8WWZ7 Cholesterol transporter ABCA5 chr17 GO:0045595 Not Cancer Driver No 214 0.13 52 5 0.096 0
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0045595 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0045595 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0045595 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0045595 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 GO:0045595 Not Cancer Driver No 157 0.117 1294 155 0.12 0
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0045595 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0045595 Not Cancer Driver No 131 0.144 244 42 0.172 8
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0045595 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0045595 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0045595 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0045595 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0045595 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0045595 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0045595 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0045595 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 GO:0045595 Not Cancer Driver No 504 0.316 374 128 0.342 0
ADAMTS20 ADAMTS20 P59510 A disintegrin and metalloproteinase with thrombospondin motifs 20 chr12 GO:0045595 Not Cancer Driver No 495 0.259 120 33 0.275 0
ADAMTS7 ADAMTS7 Q9UKP4 A disintegrin and metalloproteinase with thrombospondin motifs 7 chr15 GO:0045595 Not Cancer Driver No 244 0.145 640 100 0.156 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0045595 Not Cancer Driver No 288 0.149 235 38 0.162 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0045595 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADGRA2 ADGRA2 Q96PE1 Adhesion G protein-coupled receptor A2 chr8 GO:0045595 Not Cancer Driver No 140 0.105 417 32 0.077 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0045595 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIG ADIG Q0VDE8 Adipogenin chr20 GO:0045595 Not Cancer Driver No 18 0.225 0 0 0.0 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0045595 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0045595 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADIRF ADIRF Q15847 Adipogenesis regulatory factor chr10 GO:0045595 Not Cancer Driver No 8 0.105 64 8 0.125 0
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0045595 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0045595 Not Cancer Driver No 130 0.118 615 66 0.107 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0045595 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0045595 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0045595 Not Cancer Driver No 95 0.265 0 0 0.0 1
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0045595 Not Cancer Driver No 120 0.1 500 56 0.112 6
AJAP1 AJAP1 Q9UKB5 Adherens junction-associated protein 1 chr1 GO:0045595 Not Cancer Driver No 103 0.251 271 64 0.236 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0045595 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0045595 Not Cancer Driver No 11 0.057 125 9 0.072 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0045595 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0045595 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0045595 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALX1 ALX1 Q15699 ALX homeobox protein 1 chr12 GO:0045595 Not Cancer Driver No 75 0.23 190 48 0.253 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0045595 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0045595 Not Cancer Driver No 104 0.127 146 26 0.178 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:0045595 Not Cancer Driver No 312 0.12 1790 221 0.123 9
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0045595 Not Cancer Driver No 34 0.094 192 18 0.094 0
ANKRD26 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 GO:0045595 Not Cancer Driver No 224 0.131 1269 164 0.129 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0045595 Not Cancer Driver No 145 0.138 239 33 0.138 0
ANKRD54 ANKRD54 Q6NXT1 Ankyrin repeat domain-containing protein 54 chr22 GO:0045595 Not Cancer Driver No 26 0.087 188 12 0.064 0
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 GO:0045595 Not Cancer Driver No 22 0.088 117 12 0.103 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0045595 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP1AR AP1AR Q63HQ0 AP-1 complex-associated regulatory protein chr4 GO:0045595 Not Cancer Driver No 24 0.079 257 24 0.093 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0045595 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0045595 Not Cancer Driver No 138 0.12 404 59 0.146 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0045595 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0045595 Not Cancer Driver No 117 0.051 1725 78 0.045 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0045595 Not Cancer Driver No 73 0.327 0 0 0.0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0045595 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0045595 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOLD1 APOLD1 Q96LR9 Apolipoprotein L domain-containing protein 1 chr12 GO:0045595 Not Cancer Driver No 23 0.082 22 0 0.0 0
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0045595 Not Cancer Driver No 70 0.105 149 14 0.094 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0045595 Not Cancer Driver No 34 0.116 12 0 0.0 0
AREG AREG P15514 Amphiregulin chr4 GO:0045595 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX GO:0045595 Not Cancer Driver No 125 0.132 464 76 0.164 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0045595 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0045595 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0045595 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 GO:0045595 Not Cancer Driver No 40 0.133 49 8 0.163 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0045595 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 GO:0045595 Not Cancer Driver No 82 0.192 19 1 0.053 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0045595 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0045595 Not Cancer Driver No 2 0.01 166 1 0.006 0
ASPA ASPA P45381 Aspartoacylase chr17 GO:0045595 Not Cancer Driver No 58 0.185 3 0 0.0 42
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0045595 Not Cancer Driver No 554 0.159 424 67 0.158 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0045595 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ASXL2_ENST00000435504 ASXL2 Q76L83 Putative Polycomb group protein ASXL2 chr2 GO:0045595 Census, Compendium Yes 209 0.146 1275 174 0.136 0
ATAT1_ENST00000376485 ATAT1 Q5SQI0 Alpha-tubulin N-acetyltransferase 1 chr6 GO:0045595 Not Cancer Driver No 31 0.074 271 20 0.074 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0045595 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0045595 Not Cancer Driver No 63 0.178 327 55 0.168 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0045595 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP11A ATP11A P98196 Phospholipid-transporting ATPase IH chr13 GO:0045595 Not Cancer Driver No 171 0.151 77 17 0.221 0
ATRAID_ENST00000606999 ATRAID Q6UW56 All-trans retinoic acid-induced differentiation factor chr2 GO:0045595 Not Cancer Driver No 15 0.066 9 2 0.222 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0045595 Not Cancer Driver No 36 0.089 178 21 0.118 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0045595 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0045595 Census, Compendium Yes 114 0.135 547 77 0.141 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0045595 Not Cancer Driver No 168 0.188 341 64 0.188 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0045595 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0045595 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0045595 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAMBI BAMBI Q13145 BMP and activin membrane-bound inhibitor homolog chr10 GO:0045595 Not Cancer Driver No 42 0.162 31 7 0.226 0
BBS12 BBS12 Q6ZW61 Bardet-Biedl syndrome 12 protein chr4 GO:0045595 Not Cancer Driver No 88 0.124 34 5 0.147 10
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 GO:0045595 Census, Compendium Yes 210 0.251 677 171 0.253 3
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0045595 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6B BCL6B Q8N143 B-cell CLL/lymphoma 6 member B protein chr17 GO:0045595 Not Cancer Driver No 79 0.165 185 28 0.151 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0045595 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCL9L BCL9L Q86UU0 B-cell CLL/lymphoma 9-like protein chr11 GO:0045595 Census, Compendium Yes 200 0.133 1495 200 0.134 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0045595 Not Cancer Driver No 47 0.19 79 19 0.241 1
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0045595 Not Cancer Driver No 13 0.13 21 2 0.095 0
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0045595 Not Cancer Driver No 12 0.063 183 12 0.066 0
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0045595 Not Cancer Driver No 88 0.161 267 38 0.142 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0045595 Not Cancer Driver No 21 0.044 213 10 0.047 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0045595 Not Cancer Driver No 65 0.11 456 42 0.092 5
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0045595 Not Cancer Driver No 69 0.112 83 9 0.108 0
BLOC1S5 BLOC1S5 Q8TDH9 Biogenesis of lysosome-related organelles complex 1 subunit 5 chr6 GO:0045595 Not Cancer Driver No 15 0.08 153 13 0.085 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0045595 Not Cancer Driver No 12 0.07 111 11 0.099 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0045595 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0045595 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0045595 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0045595 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0045595 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0045595 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0045595 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0045595 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0045595 Compendium Yes 141 0.136 601 70 0.116 19
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0045595 Not Cancer Driver No 195 0.196 530 111 0.209 0
BOC_ENST00000355385 BOC Q9BWV1 Brother of CDO chr3 GO:0045595 Not Cancer Driver No 175 0.157 568 92 0.162 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 GO:0045595 Not Cancer Driver No 171 0.162 425 68 0.16 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0045595 Not Cancer Driver No 273 0.359 36 17 0.472 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0045595 Census, Compendium Yes 21 0.123 19 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0045595 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0045595 Not Cancer Driver No 92 0.176 24 2 0.083 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0045595 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:0045595 Not Cancer Driver No 46 0.188 134 26 0.194 1
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:0045595 Not Cancer Driver No 19 0.08 101 5 0.05 0
CALR CALR P27797 Calreticulin chr19 GO:0045595 Census Yes 45 0.108 245 31 0.127 0
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0045595 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 GO:0045595 Not Cancer Driver No 86 0.129 273 28 0.103 6
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0045595 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0045595 Not Cancer Driver No 111 0.135 168 11 0.065 52
CAPRIN1_ENST00000532820 CAPRIN1 Q14444 Caprin-1 chr11 GO:0045595 Not Cancer Driver No 84 0.118 603 72 0.119 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0045595 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 GO:0045595 Not Cancer Driver No 62 0.102 102 10 0.098 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0045595 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0045595 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0045595 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0045595 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0045595 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0045595 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0045595 Census, Compendium Yes 39 0.214 94 17 0.181 0
CCDC3 CCDC3 Q9BQI4 Coiled-coil domain-containing protein 3 chr10 GO:0045595 Not Cancer Driver No 40 0.148 68 18 0.265 0
CCDC71L CCDC71L Q8N9Z2 Coiled-coil domain-containing protein 71L chr7 GO:0045595 Not Cancer Driver No 3 0.013 193 2 0.01 0
CCDC85B CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 GO:0045595 Not Cancer Driver No 3 0.015 79 2 0.025 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0045595 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL17_ENST00000616880 CCL17 Q92583 C-C motif chemokine 17 chr16 GO:0045595 Not Cancer Driver No 10 0.106 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0045595 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0045595 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0045595 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0045595 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCN4 CCN4 O95388 CCN family member 4 chr8 GO:0045595 Not Cancer Driver No 93 0.253 20 8 0.4 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0045595 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0045595 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0045595 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD109 CD109 Q6YHK3 CD109 antigen chr6 GO:0045595 Not Cancer Driver No 204 0.141 54 11 0.204 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0045595 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0045595 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0045595 Census Yes 42 0.191 18 10 0.556 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0045595 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0045595 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0045595 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0045595 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0045595 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0045595 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0045595 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0045595 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0045595 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0045595 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDH4 CDH4 P55283 Cadherin-4 chr20 GO:0045595 Not Cancer Driver No 266 0.29 441 152 0.345 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0045595 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0045595 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK12 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 GO:0045595 Census, Compendium Yes 225 0.151 1202 160 0.133 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 GO:0045595 Not Cancer Driver No 155 0.103 1138 99 0.087 6
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0045595 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0045595 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0045595 Census Yes 40 0.123 24 3 0.125 1
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0045595 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0045595 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0045595 Not Cancer Driver No 165 0.172 685 120 0.175 18
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0045595 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0045595 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0045595 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDON CDON Q4KMG0 Cell adhesion molecule-related/down-regulated by oncogenes chr11 GO:0045595 Not Cancer Driver No 183 0.142 441 63 0.143 5
CDS1 CDS1 Q92903 Phosphatidate cytidylyltransferase 1 chr4 GO:0045595 Not Cancer Driver No 73 0.158 66 9 0.136 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0045595 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEACAM5 CEACAM5 P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 chr19 GO:0045595 Not Cancer Driver No 135 0.192 256 48 0.188 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0045595 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0045595 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPD CEBPD P49716 CCAAT/enhancer-binding protein delta chr8 GO:0045595 Not Cancer Driver No 5 0.019 234 4 0.017 0
CELA1 CELA1 Q9UNI1 Chymotrypsin-like elastase family member 1 chr12 GO:0045595 Not Cancer Driver No 48 0.186 20 0 0.0 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 GO:0045595 Not Cancer Driver No 38 0.1 36 4 0.111 0
CETP CETP P11597 Cholesteryl ester transfer protein chr16 GO:0045595 Not Cancer Driver No 58 0.118 0 0 0.0 3
CHADL CHADL Q6NUI6 Chondroadherin-like protein chr22 GO:0045595 Not Cancer Driver No 23 0.03 136 2 0.015 0
CHRD CHRD Q9H2X0 Chordin chr3 GO:0045595 Not Cancer Driver No 171 0.179 308 61 0.198 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0045595 Not Cancer Driver No 24 0.126 6 1 0.167 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0045595 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0045595 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0045595 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0045595 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLDN18 CLDN18 P56856 Claudin-18 chr3 GO:0045595 Not Cancer Driver No 44 0.169 21 5 0.238 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0045595 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0045595 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 GO:0045595 Not Cancer Driver No 32 0.133 27 5 0.185 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0045595 Not Cancer Driver No 83 0.098 458 38 0.083 0
CLPTM1 CLPTM1 O96005 Cleft lip and palate transmembrane protein 1 chr19 GO:0045595 Not Cancer Driver No 83 0.124 163 19 0.117 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0045595 Not Cancer Driver No 107 0.287 24 13 0.542 0
CMTM5 CMTM5 Q96DZ9 CKLF-like MARVEL transmembrane domain-containing protein 5 chr14 GO:0045595 Not Cancer Driver No 56 0.251 12 2 0.167 0
CNOT4_ENST00000315544 CNOT4 O95628 CCR4-NOT transcription complex subunit 4 chr7 GO:0045595 Not Cancer Driver No 73 0.127 359 35 0.097 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0045595 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0045595 Not Cancer Driver No 155 0.149 370 61 0.165 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0045595 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL5A1 COL5A1 P20908 Collagen alpha-1(V) chain chr9 GO:0045595 Not Cancer Driver No 451 0.245 1456 385 0.264 7
COL5A2 COL5A2 P05997 Collagen alpha-2(V) chain chr2 GO:0045595 Not Cancer Driver No 350 0.233 1276 297 0.233 2
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0045595 Not Cancer Driver No 61 0.129 84 13 0.155 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0045595 Compendium Yes 383 0.188 151 42 0.278 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0045595 Not Cancer Driver No 27 0.196 23 6 0.261 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0045595 Not Cancer Driver No 155 0.121 72 0 0.0 5
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0045595 Census Yes 25 0.076 277 23 0.083 0
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0045595 Not Cancer Driver No 15 0.125 78 5 0.064 0
CRIM1 CRIM1 Q9NZV1 Cysteine-rich motor neuron 1 protein chr2 GO:0045595 Not Cancer Driver No 133 0.128 35 4 0.114 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0045595 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0045595 Not Cancer Driver No 38 0.125 160 25 0.156 0
CRP CRP P02741 C-reactive protein chr1 GO:0045595 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0045595 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0045595 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0045595 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0045595 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 GO:0045595 Census, Compendium Yes 131 0.157 209 34 0.163 2
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0045595 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0045595 Not Cancer Driver No 62 0.149 133 18 0.135 0
CSPG5 CSPG5 O95196 Chondroitin sulfate proteoglycan 5 chr3 GO:0045595 Not Cancer Driver No 75 0.133 397 46 0.116 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 GO:0045595 Not Cancer Driver No 121 0.126 624 87 0.139 0
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 GO:0045595 Not Cancer Driver No 34 0.13 46 2 0.043 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 GO:0045595 Not Cancer Driver No 45 0.111 49 6 0.122 2
CTHRC1 CTHRC1 Q96CG8 Collagen triple helix repeat-containing protein 1 chr8 GO:0045595 Not Cancer Driver No 31 0.128 62 5 0.081 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0045595 Not Cancer Driver No 37 0.166 3 0 0.0 1
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0045595 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0045595 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0045595 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:0045595 Not Cancer Driver No 164 0.14 385 48 0.125 0
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:0045595 Not Cancer Driver No 64 0.084 102 2 0.02 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0045595 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0045595 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0045595 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0045595 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0045595 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0045595 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0045595 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0045595 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0045595 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0045595 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0045595 Not Cancer Driver No 71 0.14 79 13 0.165 18
DAAM2 DAAM2 Q86T65 Disheveled-associated activator of morphogenesis 2 chr6 GO:0045595 Not Cancer Driver No 183 0.171 272 55 0.202 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0045595 Not Cancer Driver No 200 0.34 393 143 0.364 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0045595 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0045595 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT3 DACT3 Q96B18 Dapper homolog 3 chr19 GO:0045595 Not Cancer Driver No 17 0.027 549 12 0.022 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0045595 Not Cancer Driver No 102 0.114 485 61 0.126 4
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0045595 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0045595 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0045595 Census, Compendium Yes 530 0.366 631 215 0.341 2
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0045595 Compendium Yes 150 0.319 6 3 0.5 0
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0045595 Not Cancer Driver No 113 0.218 19 4 0.211 2
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0045595 Census Yes 29 0.172 160 27 0.169 0
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0045595 Census Yes 192 0.225 118 34 0.288 7
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0045595 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0045595 Census Yes 74 0.121 225 23 0.102 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0045595 Not Cancer Driver No 159 0.158 222 39 0.176 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0045595 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0045595 Not Cancer Driver No 181 0.115 375 49 0.131 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0045595 Not Cancer Driver No 132 0.155 514 82 0.16 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0045595 Not Cancer Driver No 58 0.218 47 8 0.17 0
DKKL1 DKKL1 Q9UK85 Dickkopf-like protein 1 chr19 GO:0045595 Not Cancer Driver No 44 0.182 136 31 0.228 0
DLK2_ENST00000372488 DLK2 Q6UY11 Protein delta homolog 2 chr6 GO:0045595 Not Cancer Driver No 49 0.128 39 3 0.077 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0045595 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLL3 DLL3 Q9NYJ7 Delta-like protein 3 chr19 GO:0045595 Not Cancer Driver No 73 0.118 119 10 0.084 1
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0045595 Not Cancer Driver No 25 0.098 183 21 0.115 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0045595 Not Cancer Driver No 46 0.14 262 38 0.145 0
DMPK_ENST00000291270 DMPK Q09013 Myotonin-protein kinase chr19 GO:0045595 Not Cancer Driver No 54 0.086 220 14 0.064 0
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0045595 Not Cancer Driver No 25 0.046 325 19 0.058 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0045595 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 GO:0045595 Not Cancer Driver No 52 0.145 141 21 0.149 2
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0045595 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0045595 Not Cancer Driver No 203 0.126 702 78 0.111 4
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0045595 Not Cancer Driver No 240 0.129 360 52 0.144 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0045595 Not Cancer Driver No 278 0.149 330 45 0.136 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 GO:0045595 Not Cancer Driver No 67 0.171 179 30 0.168 5
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0045595 Not Cancer Driver No 61 0.175 249 48 0.193 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0045595 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0045595 Not Cancer Driver No 88 0.22 45 17 0.378 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0045595 Census, Compendium Yes 175 0.127 682 100 0.147 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0045595 Not Cancer Driver No 652 0.324 603 201 0.333 0
DSPP_ENST00000282478 DSPP Q9NZW4 Dentin sialophosphoprotein chr4 GO:0045595 Not Cancer Driver No 208 0.16 1278 206 0.161 8
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0045595 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP15 DUSP15 Q9H1R2 Dual specificity protein phosphatase 15 chr20 GO:0045595 Not Cancer Driver No 36 0.122 122 19 0.156 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 GO:0045595 Not Cancer Driver No 7 0.062 1 0 0.0 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0045595 Not Cancer Driver No 49 0.112 272 23 0.085 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0045595 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0045595 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0045595 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFEMP1_ENST00000355426 EFEMP1 Q12805 EGF-containing fibulin-like extracellular matrix protein 1 chr2 GO:0045595 Not Cancer Driver No 95 0.193 73 21 0.288 1
EFEMP2 EFEMP2 O95967 EGF-containing fibulin-like extracellular matrix protein 2 chr11 GO:0045595 Not Cancer Driver No 67 0.151 41 4 0.098 8
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0045595 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0045595 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0045595 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0045595 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0045595 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0045595 Compendium Yes 90 0.189 352 59 0.168 11
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0045595 Not Cancer Driver No 60 0.155 252 46 0.183 0
EID1 EID1 Q9Y6B2 EP300-interacting inhibitor of differentiation 1 chr15 GO:0045595 Not Cancer Driver No 22 0.118 159 17 0.107 0
EID2B EID2B Q96D98 EP300-interacting inhibitor of differentiation 2B chr19 GO:0045595 Not Cancer Driver No 9 0.056 90 2 0.022 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0045595 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0045595 Not Cancer Driver No 104 0.115 382 43 0.113 0
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 GO:0045595 Not Cancer Driver No 30 0.122 17 3 0.176 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0045595 Not Cancer Driver No 50 0.126 186 13 0.07 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0045595 Not Cancer Driver No 24 0.144 0 0 0.0 2
ENG ENG P17813 Endoglin chr9 GO:0045595 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0045595 Not Cancer Driver No 148 0.16 101 5 0.05 33
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0045595 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0045595 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0045595 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0045595 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0045595 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0045595 Census, Compendium Yes 275 0.219 314 41 0.131 1
EREG EREG O14944 Proepiregulin chr4 GO:0045595 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0045595 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESRP1_ENST00000642581 ESRP1 Q6NXG1 Epithelial splicing regulatory protein 1 chr8 GO:0045595 Not Cancer Driver No 120 0.176 41 5 0.122 1
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 GO:0045595 Compendium Yes 37 0.087 101 9 0.089 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0045595 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0045595 Not Cancer Driver No 68 0.154 78 9 0.115 0
ETV2_ENST00000403402 ETV2 O00321 ETS translocation variant 2 chr19 GO:0045595 Not Cancer Driver No 23 0.067 227 15 0.066 0
ETV4_ENST00000591713 ETV4 P43268 ETS translocation variant 4 chr17 GO:0045595 Census, Compendium Yes 44 0.091 319 26 0.082 0
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 GO:0045595 Not Cancer Driver No 63 0.141 373 55 0.147 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0045595 Census, Compendium Yes 120 0.161 284 44 0.155 11
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0045595 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:0045595 Not Cancer Driver No 115 0.185 97 25 0.258 10
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0045595 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0045595 Not Cancer Driver No 99 0.133 206 20 0.097 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 GO:0045595 Not Cancer Driver No 33 0.057 188 3 0.016 9
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0045595 Not Cancer Driver No 10 0.052 32 0 0.0 0
FAM57B TLCD3B Q71RH2 Ceramide synthase chr16 GO:0045595 Not Cancer Driver No 40 0.146 6 3 0.5 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 GO:0045595 Census, Compendium Yes 160 0.11 154 15 0.097 27
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0045595 Census, Compendium Yes 176 0.121 181 14 0.077 3
FAXDC2 FAXDC2 Q96IV6 Fatty acid hydroxylase domain-containing protein 2 chr5 GO:0045595 Not Cancer Driver No 39 0.117 9 0 0.0 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0045595 Compendium Yes 122 0.174 22 3 0.136 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0045595 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0045595 Compendium Yes 607 0.208 135 24 0.178 30
FBXO22 FBXO22 Q8NEZ5 F-box only protein 22 chr15 GO:0045595 Not Cancer Driver No 65 0.161 15 3 0.2 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0045595 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0045595 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0045595 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0045595 Census, Compendium Yes 322 0.455 230 38 0.165 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0045595 Not Cancer Driver No 68 0.114 120 4 0.033 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0045595 Census Yes 51 0.165 99 30 0.303 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0045595 Not Cancer Driver No 193 0.263 217 44 0.203 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0045595 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0045595 Census Yes 103 0.125 245 34 0.139 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0045595 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0045595 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0045595 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0045595 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0045595 Not Cancer Driver No 70 0.286 96 33 0.344 2
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0045595 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0045595 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0045595 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0045595 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0045595 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0045595 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0045595 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0045595 Not Cancer Driver No 81 0.179 53 8 0.151 8
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0045595 Not Cancer Driver No 71 0.162 70 12 0.171 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0045595 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLNA FLNA P21333 Filamin-A chrX GO:0045595 Census Yes 416 0.157 1456 214 0.147 28
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0045595 Not Cancer Driver No 56 0.131 20 3 0.15 0
FN1 FN1 P02751 Fibronectin chr2 GO:0045595 Compendium Yes 394 0.159 1243 185 0.149 8
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 GO:0045595 Not Cancer Driver No 17 0.08 74 8 0.108 0
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0045595 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOS FOS P01100 Protein c-Fos chr14 GO:0045595 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0045595 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0045595 Compendium Yes 70 0.153 258 34 0.132 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0045595 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0045595 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0045595 Not Cancer Driver No 132 0.27 322 79 0.245 2
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0045595 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXJ2 FOXJ2 Q9P0K8 Forkhead box protein J2 chr12 GO:0045595 Not Cancer Driver No 81 0.141 483 65 0.135 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0045595 Not Cancer Driver No 90 0.139 483 65 0.135 2
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0045595 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0045595 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX GO:0045595 Census Yes 75 0.149 441 61 0.138 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0045595 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0045595 Not Cancer Driver No 38 0.088 186 16 0.086 10
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0045595 Not Cancer Driver No 69 0.136 415 58 0.14 0
FRZB FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0045595 Not Cancer Driver No 58 0.178 31 6 0.194 1
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0045595 Not Cancer Driver No 31 0.24 0 0 0.0 1
FST FST P19883 Follistatin chr5 GO:0045595 Not Cancer Driver No 50 0.145 20 7 0.35 0
FSTL3 FSTL3 O95633 Follistatin-related protein 3 chr19 GO:0045595 Census Yes 17 0.065 28 2 0.071 0
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 GO:0045595 Not Cancer Driver No 134 0.159 96 12 0.125 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0045595 Not Cancer Driver No 67 0.133 53 10 0.189 3
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0045595 Not Cancer Driver No 38 0.091 43 4 0.093 0
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0045595 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0045595 Not Cancer Driver No 90 0.157 22 2 0.091 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0045595 Not Cancer Driver No 86 0.167 28 3 0.107 58
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:0045595 Not Cancer Driver No 58 0.128 103 8 0.078 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0045595 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0045595 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0045595 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0045595 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0045595 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0045595 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0045595 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0045595 Not Cancer Driver No 92 0.155 166 27 0.163 0
GCM1 GCM1 Q9NP62 Chorion-specific transcription factor GCMa chr6 GO:0045595 Not Cancer Driver No 78 0.179 194 36 0.186 0
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0045595 Not Cancer Driver No 40 0.1 3 0 0.0 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0045595 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0045595 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0045595 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0045595 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0045595 Not Cancer Driver No 69 0.154 34 6 0.176 2
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0045595 Not Cancer Driver No 47 0.223 83 18 0.217 2
GDPD2_ENST00000374382 GDPD2 Q9HCC8 Glycerophosphoinositol inositolphosphodiesterase GDPD2 chrX GO:0045595 Not Cancer Driver No 96 0.178 43 15 0.349 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0045595 Not Cancer Driver No 65 0.15 288 42 0.146 62
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0045595 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0045595 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLG1_ENST00000422840 GLG1 Q92896 Golgi apparatus protein 1 chr16 GO:0045595 Not Cancer Driver No 134 0.114 103 7 0.068 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0045595 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0045595 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0045595 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLIPR2 GLIPR2 Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 chr9 GO:0045595 Not Cancer Driver No 16 0.104 77 10 0.13 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 GO:0045595 Census, Compendium Yes 48 0.134 10 0 0.0 5
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 GO:0045595 Not Cancer Driver No 51 0.15 13 1 0.077 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0045595 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GORASP1 GORASP1 Q9BQQ3 Golgi reassembly-stacking protein 1 chr3 GO:0045595 Not Cancer Driver No 49 0.111 293 32 0.109 0
GPC1 GPC1 P35052 Glypican-1 chr2 GO:0045595 Not Cancer Driver No 58 0.104 166 14 0.084 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0045595 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:0045595 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR137_ENST00000313074 GPR137 Q96N19 Integral membrane protein GPR137 chr11 GO:0045595 Not Cancer Driver No 66 0.158 41 11 0.268 0
GPR171_ENST00000617554 GPR171 O14626 G-protein coupled receptor 171 chr3 GO:0045595 Not Cancer Driver No 50 0.157 8 2 0.25 0
GPR37L1 GPR37L1 O60883 G-protein coupled receptor 37-like 1 chr1 GO:0045595 Not Cancer Driver No 62 0.129 81 8 0.099 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:0045595 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0045595 Not Cancer Driver No 42 0.115 45 1 0.022 1
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0045595 Not Cancer Driver No 29 0.089 319 26 0.082 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0045595 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL1 GRHL1 Q9NZI5 Grainyhead-like protein 1 homolog chr2 GO:0045595 Not Cancer Driver No 99 0.16 256 36 0.141 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0045595 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0045595 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0045595 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0045595 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0045595 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0045595 Not Cancer Driver No 44 0.145 210 26 0.124 1
H1FOO H1-8 Q8IZA3 Histone H1.8 chr3 GO:0045595 Not Cancer Driver No 28 0.081 322 26 0.081 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0045595 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0045595 Not Cancer Driver No 59 0.159 171 32 0.187 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0045595 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0045595 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0045595 Not Cancer Driver No 100 0.181 17 7 0.412 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0045595 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0045595 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0045595 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0045595 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0045595 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0045595 Not Cancer Driver No 182 0.168 749 132 0.176 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 GO:0045595 Not Cancer Driver No 118 0.105 718 73 0.102 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0045595 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0045595 Not Cancer Driver No 91 0.096 570 50 0.088 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0045595 Not Cancer Driver No 286 0.283 631 178 0.282 0
HEMGN_ENST00000259456 HEMGN Q9BXL5 Hemogen chr9 GO:0045595 Not Cancer Driver No 78 0.161 473 73 0.154 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0045595 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0045595 Not Cancer Driver No 1 0.006 73 0 0.0 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0045595 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0045595 Not Cancer Driver No 64 0.19 179 26 0.145 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0045595 Compendium Yes 233 0.32 43 16 0.372 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0045595 Not Cancer Driver No 37 0.106 77 9 0.117 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0045595 Census Yes 118 0.143 435 51 0.117 0
HIST1H4A H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 15 0.146 31 5 0.161 0
HIST1H4B H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 29 0.282 31 6 0.194 0
HIST1H4C H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 29 0.282 31 7 0.226 0
HIST1H4D H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 32 0.311 31 8 0.258 0
HIST1H4E H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 45 0.437 31 14 0.452 0
HIST1H4F H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 30 0.291 31 7 0.226 0
HIST1H4H H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 22 0.214 31 9 0.29 0
HIST1H4I H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 33 0.32 31 10 0.323 0
HIST1H4J H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 26 0.252 31 9 0.29 0
HIST1H4K H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 44 0.427 31 13 0.419 0
HIST1H4L H4-16 P62805 Histone H4 chr6 GO:0045595 Not Cancer Driver No 25 0.243 31 14 0.452 0
HIST4H4 H4-16 P62805 Histone H4 chr12 GO:0045595 Not Cancer Driver No 21 0.204 31 7 0.226 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0045595 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 GO:0045595 Not Cancer Driver No 39 0.156 7 1 0.143 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0045595 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0045595 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0045595 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0045595 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0045595 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0045595 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGB3 HMGB3 O15347 High mobility group protein B3 chrX GO:0045595 Not Cancer Driver No 37 0.185 182 32 0.176 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0045595 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 GO:0045595 Census Yes 79 0.11 493 55 0.112 0
HOPX_ENST00000317745 HOPX Q9BPY8 Homeodomain-only protein chr4 GO:0045595 Not Cancer Driver No 13 0.178 48 10 0.208 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0045595 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA2 HOXA2 O43364 Homeobox protein Hox-A2 chr7 GO:0045595 Not Cancer Driver No 58 0.154 281 48 0.171 1
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 GO:0045595 Not Cancer Driver No 43 0.159 209 37 0.177 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0045595 Not Cancer Driver No 60 0.261 71 15 0.211 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 GO:0045595 Census Yes 46 0.169 187 35 0.187 0
HOXB4 HOXB4 P17483 Homeobox protein Hox-B4 chr17 GO:0045595 Not Cancer Driver No 41 0.163 210 33 0.157 0
HOXB8 HOXB8 P17481 Homeobox protein Hox-B8 chr17 GO:0045595 Not Cancer Driver No 35 0.144 121 15 0.124 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0045595 Not Cancer Driver No 60 0.144 12 0 0.0 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0045595 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0045595 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0045595 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 GO:0045595 Not Cancer Driver No 67 0.099 283 26 0.092 2
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0045595 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0045595 Not Cancer Driver No 140 0.306 40 11 0.275 0
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0045595 Not Cancer Driver No 22 0.247 10 2 0.2 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0045595 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0045595 Not Cancer Driver No 14 0.104 52 7 0.135 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0045595 Census, Compendium Yes 14 0.118 34 4 0.118 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0045595 Not Cancer Driver No 4 0.025 71 1 0.014 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 GO:0045595 Not Cancer Driver No 19 0.152 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0045595 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0045595 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0045595 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0045595 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0045595 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0045595 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0045595 Not Cancer Driver No 41 0.141 103 25 0.243 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0045595 Not Cancer Driver No 27 0.099 112 17 0.152 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0045595 Not Cancer Driver No 58 0.141 111 15 0.135 6
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0045595 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 GO:0045595 Census, Compendium Yes 106 0.208 284 60 0.211 1
IL10 IL10 P22301 Interleukin-10 chr1 GO:0045595 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0045595 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0045595 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0045595 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL15RA_ENST00000379977 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 GO:0045595 Not Cancer Driver No 40 0.15 173 32 0.185 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0045595 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0045595 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17RD IL17RD Q8NFM7 Interleukin-17 receptor D chr3 GO:0045595 Not Cancer Driver No 98 0.133 177 17 0.096 7
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0045595 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0045595 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0045595 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0045595 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0045595 Census Yes 24 0.157 6 1 0.167 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:0045595 Not Cancer Driver No 30 0.17 0 0 0.0 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0045595 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0045595 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0045595 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0045595 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0045595 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0045595 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0045595 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0045595 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0045595 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0045595 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0045595 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0045595 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0045595 Census, Compendium Yes 177 0.386 88 48 0.545 1
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0045595 Not Cancer Driver No 45 0.1 71 9 0.127 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0045595 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0045595 Not Cancer Driver No 148 0.347 154 63 0.409 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0045595 Not Cancer Driver No 176 0.148 578 90 0.156 0
INS INS P01308 Insulin chr11 GO:0045595 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0045595 Not Cancer Driver No 37 0.134 43 1 0.023 0
IQCB1 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 GO:0045595 Not Cancer Driver No 72 0.12 88 8 0.091 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0045595 Compendium Yes 49 0.151 228 31 0.136 2
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0045595 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0045595 Not Cancer Driver No 43 0.085 253 19 0.075 1
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0045595 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0045595 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISLR2_ENST00000565159 ISLR2 Q6UXK2 Immunoglobulin superfamily containing leucine-rich repeat protein 2 chr15 GO:0045595 Not Cancer Driver No 128 0.172 344 49 0.142 0
IST1_ENST00000541571 IST1 P53990 IST1 homolog chr16 GO:0045595 Not Cancer Driver No 31 0.085 185 17 0.092 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0045595 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0045595 Census Yes 153 0.146 92 9 0.098 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0045595 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0045595 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0045595 Not Cancer Driver No 124 0.157 66 5 0.076 30
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0045595 Not Cancer Driver No 28 0.061 216 7 0.032 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0045595 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0045595 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0045595 Census, Compendium Yes 167 0.149 63 10 0.159 7
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0045595 Not Cancer Driver No 16 0.098 142 13 0.092 0
JUND JUND P17535 Transcription factor JunD chr19 GO:0045595 Not Cancer Driver No 21 0.061 313 19 0.061 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0045595 Not Cancer Driver No 183 0.135 804 100 0.124 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0045595 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0045595 Census Yes 97 0.159 327 47 0.144 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0045595 Not Cancer Driver No 61 0.153 277 50 0.181 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0045595 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0045595 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0045595 Not Cancer Driver No 122 0.115 337 44 0.131 0
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 GO:0045595 Not Cancer Driver No 124 0.117 309 40 0.129 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0045595 Census, Compendium Yes 357 0.263 275 55 0.2 2
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0045595 Census, Compendium Yes 237 0.38 57 12 0.211 0
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0045595 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0045595 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0045595 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0045595 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 GO:0045595 Not Cancer Driver No 59 0.123 349 46 0.132 0
KLF13 KLF13 Q9Y2Y9 Krueppel-like factor 13 chr15 GO:0045595 Not Cancer Driver No 18 0.062 246 13 0.053 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0045595 Compendium Yes 77 0.168 366 40 0.109 0
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0045595 Not Cancer Driver No 46 0.152 72 7 0.097 0
KLHL41 KLHL41 O60662 Kelch-like protein 41 chr2 GO:0045595 Not Cancer Driver No 69 0.114 18 2 0.111 1
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0045595 Not Cancer Driver No 62 0.254 28 12 0.429 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0045595 Census, Compendium Yes 788 4.169 7 2 0.286 27
KRT36 KRT36 O76013 Keratin, type I cuticular Ha6 chr17 GO:0045595 Not Cancer Driver No 99 0.212 52 18 0.346 0
KRT84 KRT84 Q9NSB2 Keratin, type II cuticular Hb4 chr12 GO:0045595 Not Cancer Driver No 101 0.168 41 4 0.098 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX GO:0045595 Not Cancer Driver No 228 0.181 442 75 0.17 54
L3MBTL1 L3MBTL1 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 chr20 GO:0045595 Not Cancer Driver No 116 0.138 447 40 0.089 0
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0045595 Not Cancer Driver No 47 0.09 208 11 0.053 0
LBH LBH Q53QV2 Protein LBH chr2 GO:0045595 Not Cancer Driver No 15 0.143 72 10 0.139 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0045595 Compendium Yes 56 0.136 177 29 0.164 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0045595 Not Cancer Driver No 119 0.138 63 3 0.048 104
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0045595 Not Cancer Driver No 66 0.216 191 39 0.204 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0045595 Census Yes 64 0.16 370 57 0.154 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:0045595 Not Cancer Driver No 74 0.111 611 69 0.113 0
LEP LEP P41159 Leptin chr7 GO:0045595 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0045595 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS12_ENST00000394618 LGALS12 Q96DT0 Galectin-12 chr11 GO:0045595 Not Cancer Driver No 49 0.146 8 2 0.25 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0045595 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0045595 Not Cancer Driver No 54 0.152 65 16 0.246 0
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 GO:0045595 Not Cancer Driver No 60 0.148 203 28 0.138 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0045595 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0045595 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0045595 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0045595 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 GO:0045595 Not Cancer Driver No 58 0.086 428 36 0.084 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0045595 Not Cancer Driver No 110 0.17 170 30 0.176 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0045595 Not Cancer Driver No 34 0.105 0 0 0.0 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0045595 Not Cancer Driver No 55 0.161 8 0 0.0 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0045595 Not Cancer Driver No 37 0.177 86 12 0.14 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0045595 Not Cancer Driver No 30 0.207 1 0 0.0 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0045595 Not Cancer Driver No 99 0.177 456 84 0.184 1
LNPK_ENST00000272748 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 GO:0045595 Not Cancer Driver No 62 0.145 257 43 0.167 0
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:0045595 Compendium Yes 44 0.106 172 11 0.064 4
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 GO:0045595 Not Cancer Driver No 134 0.173 39 4 0.103 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0045595 Not Cancer Driver No 91 0.121 86 17 0.198 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0045595 Not Cancer Driver No 65 0.184 9 0 0.0 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0045595 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0045595 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP3 LRP3 O75074 Low-density lipoprotein receptor-related protein 3 chr19 GO:0045595 Not Cancer Driver No 88 0.114 214 20 0.093 0
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0045595 Not Cancer Driver No 233 0.122 265 28 0.106 11
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0045595 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0045595 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRC17 LRRC17 Q8N6Y2 Leucine-rich repeat-containing protein 17 chr7 GO:0045595 Not Cancer Driver No 58 0.132 88 11 0.125 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0045595 Not Cancer Driver No 105 0.13 32 3 0.094 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0045595 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0045595 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTBP3 LTBP3 Q9NS15 Latent-transforming growth factor beta-binding protein 3 chr11 GO:0045595 Not Cancer Driver No 108 0.083 356 22 0.062 0
LTF LTF P02788 Lactotransferrin chr3 GO:0045595 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0045595 Census Yes 95 0.186 84 12 0.143 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0045595 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0045595 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0045595 Census Yes 35 0.108 301 34 0.113 10
MAFF_ENST00000426621 MAFF Q9ULX9 Transcription factor MafF chr22 GO:0045595 Not Cancer Driver No 9 0.055 118 7 0.059 0
MAFG MAFG O15525 Transcription factor MafG chr17 GO:0045595 Not Cancer Driver No 5 0.031 132 5 0.038 0
MAF_ENST00000393350 MAF O75444 Transcription factor Maf chr16 GO:0045595 Census, Compendium Yes 39 0.105 331 37 0.112 11
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0045595 Not Cancer Driver No 118 0.188 65 7 0.108 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0045595 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0045595 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAMSTR MAMSTR Q6ZN01 MEF2-activating motif and SAP domain-containing transcriptional regulator chr19 GO:0045595 Not Cancer Driver No 32 0.077 404 32 0.079 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0045595 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0045595 Compendium Yes 367 0.201 1726 340 0.197 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0045595 Census Yes 157 0.163 593 91 0.153 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0045595 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0045595 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0045595 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0045595 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0045595 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0045595 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0045595 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0045595 Not Cancer Driver No 161 0.203 454 108 0.238 0
MBNL3 MBNL3 Q9NUK0 Muscleblind-like protein 3 chrX GO:0045595 Not Cancer Driver No 46 0.13 180 26 0.144 0
MBOAT2 MBOAT2 Q6ZWT7 Lysophospholipid acyltransferase 2 chr2 GO:0045595 Not Cancer Driver No 59 0.113 36 6 0.167 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0045595 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0045595 Not Cancer Driver No 218 0.236 124 33 0.266 0
MCRIP1_ENST00000455127 MCRIP1 C9JLW8 Mapk-regulated corepressor-interacting protein 1 chr17 GO:0045595 Not Cancer Driver No 1 0.01 83 1 0.012 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0045595 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0045595 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0045595 Not Cancer Driver No 75 0.154 483 74 0.153 46
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0045595 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 GO:0045595 Not Cancer Driver No 24 0.135 101 18 0.178 0
MEDAG MEDAG Q5VYS4 Mesenteric estrogen-dependent adipogenesis protein chr13 GO:0045595 Not Cancer Driver No 46 0.152 1 0 0.0 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0045595 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 GO:0045595 Not Cancer Driver No 216 0.189 204 42 0.206 2
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0045595 Not Cancer Driver No 363 0.128 476 59 0.124 3
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0045595 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:0045595 Not Cancer Driver No 94 0.197 358 76 0.212 0
MELTF MELTF P08582 Melanotransferrin chr3 GO:0045595 Not Cancer Driver No 106 0.144 23 6 0.261 0
MEN1 MEN1 O00255 Menin chr11 GO:0045595 Census, Compendium Yes 73 0.119 228 15 0.066 90
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0045595 Not Cancer Driver No 8 0.03 247 7 0.028 0
METRNL METRNL Q641Q3 Meteorin-like protein chr17 GO:0045595 Not Cancer Driver No 26 0.084 88 5 0.057 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0045595 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0045595 Not Cancer Driver No 74 0.128 274 29 0.106 0
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 GO:0045595 Not Cancer Driver No 54 0.082 475 32 0.067 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:0045595 Census Yes 80 0.152 408 69 0.169 7
MIXL1_ENST00000366810 MIXL1 Q9H2W2 Homeobox protein MIXL1 chr1 GO:0045595 Not Cancer Driver No 18 0.078 157 10 0.064 0
MMP11 MMP11 P24347 Stromelysin-3 chr22 GO:0045595 Not Cancer Driver No 63 0.129 122 22 0.18 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0045595 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0045595 Not Cancer Driver No 129 0.182 124 26 0.21 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0045595 Not Cancer Driver No 44 0.153 136 21 0.154 0
MPL MPL P40238 Thrombopoietin receptor chr1 GO:0045595 Census Yes 77 0.121 129 19 0.147 14
MSR1 MSR1 P21757 Macrophage scavenger receptor types I and II chr8 GO:0045595 Not Cancer Driver No 167 0.37 241 106 0.44 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0045595 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0045595 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0045595 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0045595 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 GO:0045595 Not Cancer Driver No 45 0.149 11 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0045595 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTURN MTURN Q8N3F0 Maturin chr7 GO:0045595 Not Cancer Driver No 15 0.115 27 6 0.222 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0045595 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0045595 Census Yes 82 0.128 528 69 0.131 0
MYCL_ENST00000372816 MYCL P12524 Protein L-Myc chr1 GO:0045595 Census Yes 47 0.129 275 43 0.156 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0045595 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0045595 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0045595 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0045595 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYOC MYOC Q99972 Myocilin chr1 GO:0045595 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0045595 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0045595 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0045595 Not Cancer Driver No 36 0.161 132 20 0.152 0
N4BP2L2_ENST00000267068 N4BP2L2 Q92802 NEDD4-binding protein 2-like 2 chr13 GO:0045595 Not Cancer Driver No 81 0.139 373 55 0.147 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 GO:0045595 Not Cancer Driver No 46 0.151 169 35 0.207 0
NAPEPLD NAPEPLD Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D chr7 GO:0045595 Not Cancer Driver No 55 0.14 76 7 0.092 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 GO:0045595 Not Cancer Driver No 101 0.105 560 51 0.091 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0045595 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0045595 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0045595 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0045595 Not Cancer Driver No 22 0.1 44 4 0.091 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0045595 Not Cancer Driver No 106 0.127 516 72 0.14 0
NELL1_ENST00000357134 NELL1 Q92832 Protein kinase C-binding protein NELL1 chr11 GO:0045595 Not Cancer Driver No 238 0.294 7 3 0.429 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0045595 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0045595 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:0045595 Census, Compendium Yes 69 0.116 252 26 0.103 16
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 GO:0045595 Not Cancer Driver No 30 0.111 116 18 0.155 0
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 GO:0045595 Not Cancer Driver No 173 0.183 713 130 0.182 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 GO:0045595 Census, Compendium Yes 194 0.21 722 162 0.224 0
NFATC3 NFATC3 Q12968 Nuclear factor of activated T-cells, cytoplasmic 3 chr16 GO:0045595 Not Cancer Driver No 112 0.104 730 80 0.11 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0045595 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0045595 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0045595 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0045595 Compendium Yes 37 0.117 102 9 0.088 1
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0045595 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0045595 Not Cancer Driver No 96 0.134 443 53 0.12 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0045595 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0045595 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0045595 Census, Compendium Yes 41 0.111 334 39 0.117 7
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0045595 Not Cancer Driver No 84 0.308 206 65 0.316 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0045595 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX3-2 NKX3-2 P78367 Homeobox protein Nkx-3.2 chr4 GO:0045595 Not Cancer Driver No 36 0.108 212 27 0.127 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0045595 Not Cancer Driver No 38 0.104 325 34 0.105 0
NKX6-2 NKX6-2 Q9C056 Homeobox protein Nkx-6.2 chr10 GO:0045595 Not Cancer Driver No 27 0.097 137 23 0.168 0
NKX6-3_ENST00000518699 NKX6-3 A6NJ46 Homeobox protein Nkx-6.3 chr8 GO:0045595 Not Cancer Driver No 7 0.026 164 7 0.043 0
NLN NLN Q9BYT8 Neurolysin, mitochondrial chr5 GO:0045595 Not Cancer Driver No 70 0.099 25 3 0.12 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0045595 Not Cancer Driver No 339 0.327 64 33 0.516 37
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0045595 Not Cancer Driver No 13 0.086 11 1 0.091 0
NMRK2_ENST00000168977 NMRK2 Q9NPI5 Nicotinamide riboside kinase 2 chr19 GO:0045595 Not Cancer Driver No 25 0.109 53 9 0.17 0
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0045595 Not Cancer Driver No 33 0.077 89 3 0.034 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0045595 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0045595 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0045595 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0045595 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0045595 Not Cancer Driver No 336 0.168 464 79 0.17 0
NPHP3 NPHP3 Q7Z494 Nephrocystin-3 chr3 GO:0045595 Not Cancer Driver No 129 0.097 249 26 0.104 7
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0045595 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0045595 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0045595 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0045595 Not Cancer Driver No 47 0.118 118 9 0.076 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0045595 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1D2 NR1D2 Q14995 Nuclear receptor subfamily 1 group D member 2 chr3 GO:0045595 Not Cancer Driver No 76 0.131 223 25 0.112 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0045595 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0045595 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0045595 Not Cancer Driver No 75 0.195 57 6 0.105 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0045595 Not Cancer Driver No 9 0.079 11 1 0.091 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0045595 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0045595 Compendium Yes 146 0.158 211 31 0.147 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 GO:0045595 Not Cancer Driver No 112 0.146 221 21 0.095 1
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0045595 Not Cancer Driver No 57 0.094 66 4 0.061 2
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0045595 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0045595 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0045595 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 GO:0045595 Not Cancer Driver No 233 0.123 553 60 0.108 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 GO:0045595 Not Cancer Driver No 37 0.151 169 25 0.148 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0045595 Not Cancer Driver No 22 0.039 52 6 0.115 0
OLFM1 OLFM1 Q99784 Noelin chr9 GO:0045595 Not Cancer Driver No 88 0.181 83 10 0.12 0
OLFM2 OLFM2 O95897 Noelin-2 chr19 GO:0045595 Not Cancer Driver No 74 0.163 16 2 0.125 0
OLFM4 OLFM4 Q6UX06 Olfactomedin-4 chr13 GO:0045595 Not Cancer Driver No 117 0.229 54 11 0.204 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0045595 Census Yes 37 0.115 256 37 0.145 0
OPALIN OPALIN Q96PE5 Opalin chr10 GO:0045595 Not Cancer Driver No 29 0.206 86 18 0.209 0
OR10J5 OR10J5 Q8NHC4 Olfactory receptor 10J5 chr1 GO:0045595 Not Cancer Driver No 95 0.307 0 0 0.0 0
OSM OSM P13725 Oncostatin-M chr22 GO:0045595 Not Cancer Driver No 43 0.171 114 24 0.211 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0045595 Not Cancer Driver No 57 0.214 67 17 0.254 0
OSTN OSTN P61366 Osteocrin chr3 GO:0045595 Not Cancer Driver No 30 0.226 54 13 0.241 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0045595 Not Cancer Driver No 36 0.111 278 29 0.104 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0045595 Not Cancer Driver No 29 0.105 139 8 0.058 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0045595 Not Cancer Driver No 61 0.12 79 15 0.19 1
P4HTM_ENST00000383729 P4HTM Q9NXG6 Transmembrane prolyl 4-hydroxylase chr3 GO:0045595 Not Cancer Driver No 76 0.151 144 20 0.139 1
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 GO:0045595 Not Cancer Driver No 23 0.128 3 0 0.0 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:0045595 Not Cancer Driver No 77 0.145 378 56 0.148 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0045595 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0045595 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0045595 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0045595 Not Cancer Driver No 74 0.127 172 23 0.134 0
PARP6 PARP6 Q2NL67 Protein mono-ADP-ribosyltransferase PARP6 chr15 GO:0045595 Not Cancer Driver No 87 0.138 67 13 0.194 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0045595 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0045595 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0045595 Census Yes 84 0.187 291 55 0.189 4
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0045595 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0045595 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 GO:0045595 Census Yes 152 0.075 1665 134 0.08 0
PDCD2 PDCD2 Q16342 Programmed cell death protein 2 chr6 GO:0045595 Not Cancer Driver No 32 0.093 42 6 0.143 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0045595 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0045595 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0045595 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0045595 Census Yes 37 0.154 99 22 0.222 2
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0045595 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 GO:0045595 Not Cancer Driver No 48 0.105 244 20 0.082 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0045595 Not Cancer Driver No 37 0.228 96 24 0.25 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0045595 Not Cancer Driver No 13 0.129 0 0 0.0 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0045595 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0045595 Not Cancer Driver No 111 0.193 160 28 0.175 0
PHLDB1 PHLDB1 Q86UU1 Pleckstrin homology-like domain family B member 1 chr11 GO:0045595 Not Cancer Driver No 160 0.116 1071 130 0.121 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0045595 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PI16 PI16 Q6UXB8 Peptidase inhibitor 16 chr6 GO:0045595 Not Cancer Driver No 64 0.138 256 28 0.109 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0045595 Not Cancer Driver No 70 0.111 266 31 0.117 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0045595 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0045595 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0045595 Census, Compendium Yes 71 0.227 27 8 0.296 0
PITHD1 PITHD1 Q9GZP4 PITH domain-containing protein 1 chr1 GO:0045595 Not Cancer Driver No 26 0.123 119 11 0.092 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0045595 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0045595 Not Cancer Driver No 36 0.073 124 0 0.0 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0045595 Not Cancer Driver No 176 0.2 434 98 0.226 8
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0045595 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G2A_ENST00000375111 PLA2G2A P14555 Phospholipase A2, membrane associated chr1 GO:0045595 Not Cancer Driver No 25 0.174 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0045595 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0045595 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0045595 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0045595 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLEKHB1 PLEKHB1 Q9UF11 Pleckstrin homology domain-containing family B member 1 chr11 GO:0045595 Not Cancer Driver No 25 0.103 47 4 0.085 0
PLEKHB2_ENST00000409279 PLEKHB2 Q96CS7 Pleckstrin homology domain-containing family B member 2 chr2 GO:0045595 Not Cancer Driver No 40 0.18 42 11 0.262 0
PLPP7 PLPP7 Q8NBV4 Inactive phospholipid phosphatase 7 chr9 GO:0045595 Not Cancer Driver No 45 0.166 72 9 0.125 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0045595 Not Cancer Driver No 243 0.13 199 34 0.171 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0045595 Not Cancer Driver No 38 0.131 29 2 0.069 5
POFUT2 POFUT2 Q9Y2G5 GDP-fucose protein O-fucosyltransferase 2 chr21 GO:0045595 Not Cancer Driver No 62 0.145 5 0 0.0 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0045595 Not Cancer Driver No 62 0.092 93 4 0.043 9
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0045595 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0045595 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0045595 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0045595 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0045595 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0045595 Census Yes 72 0.143 44 4 0.091 3
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0045595 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0045595 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0045595 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0045595 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0045595 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0045595 Not Cancer Driver No 44 0.097 30 3 0.1 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0045595 Compendium Yes 85 0.163 140 27 0.193 7
PRAMEF1 PRAMEF1 O95521 PRAME family member 1 chr1 GO:0045595 Not Cancer Driver No 142 0.3 7 0 0.0 0
PRAMEF10 PRAMEF10 O60809 PRAME family member 10 chr1 GO:0045595 Not Cancer Driver No 91 0.192 7 1 0.143 0
PRAMEF11 PRAMEF11 O60813 PRAME family member 11 chr1 GO:0045595 Not Cancer Driver No 158 0.331 4 0 0.0 0
PRAMEF12 PRAMEF12 O95522 PRAME family member 12 chr1 GO:0045595 Not Cancer Driver No 122 0.253 6 6 1.0 0
PRAMEF14 PRAMEF14 Q5SWL7 PRAME family member 14 chr1 GO:0045595 Not Cancer Driver No 31 0.065 6 0 0.0 0
PRAMEF17 PRAMEF17 Q5VTA0 PRAME family member 17 chr1 GO:0045595 Not Cancer Driver No 34 0.072 10 3 0.3 0
PRAMEF2 PRAMEF2 O60811 PRAME family member 2 chr1 GO:0045595 Not Cancer Driver No 142 0.3 5 0 0.0 0
PRAMEF20 PRAMEF20 Q5VT98 PRAME family member 20 chr1 GO:0045595 Not Cancer Driver No 29 0.061 0 0 0.0 0
PRAMEF25 PRAMEF25 A6NGN4 PRAME family member 25 chr1 GO:0045595 Not Cancer Driver No 1 0.002 4 0 0.0 0
PRAMEF4 PRAMEF4 O60810 PRAME family member 4 chr1 GO:0045595 Not Cancer Driver No 135 0.282 4 3 0.75 0
PRAMEF5 PRAMEF5 Q5TYX0 PRAME family member 5 chr1 GO:0045595 Not Cancer Driver No 13 0.027 4 0 0.0 0
PRAMEF6 PRAMEF6 Q5VXH4 PRAME family member 6 chr1 GO:0045595 Not Cancer Driver No 47 0.099 4 2 0.5 0
PRAMEF7_ENST00000330881 PRAMEF7 Q5VXH5 PRAME family member 7 chr1 GO:0045595 Not Cancer Driver No 47 0.099 9 0 0.0 0
PRAME_ENST00000402697 PRAME P78395 Melanoma antigen preferentially expressed in tumors chr22 GO:0045595 Not Cancer Driver No 95 0.187 10 1 0.1 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0045595 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRDM6 PRDM6 Q9NQX0 Putative histone-lysine N-methyltransferase PRDM6 chr5 GO:0045595 Not Cancer Driver No 29 0.049 241 7 0.029 2
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0045595 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0045595 Not Cancer Driver No 21 0.096 44 2 0.045 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0045595 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRICKLE1_ENST00000640055 PRICKLE1 Q96MT3 Prickle-like protein 1 chr12 GO:0045595 Not Cancer Driver No 146 0.176 485 91 0.188 3
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0045595 Census Yes 53 0.151 24 0 0.0 2
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0045595 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0045595 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0045595 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0045595 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0045595 Census Yes 201 0.22 189 33 0.175 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0045595 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX GO:0045595 Not Cancer Driver No 54 0.151 69 3 0.043 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0045595 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0045595 Not Cancer Driver No 83 0.13 72 6 0.083 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 GO:0045595 Not Cancer Driver No 43 0.115 71 7 0.099 0
PROC PROC P04070 Vitamin K-dependent protein C chr2 GO:0045595 Not Cancer Driver No 73 0.158 41 9 0.22 36
PROM1 PROM1 O43490 Prominin-1 chr4 GO:0045595 Not Cancer Driver No 94 0.109 76 9 0.118 3
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0045595 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0045595 Not Cancer Driver No 71 0.141 109 16 0.147 0
PRTG PRTG Q2VWP7 Protogenin chr15 GO:0045595 Not Cancer Driver No 192 0.167 271 49 0.181 0
PRXL2A PRXL2A Q9BRX8 Peroxiredoxin-like 2A chr10 GO:0045595 Not Cancer Driver No 34 0.148 0 0 0.0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0045595 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:0045595 Not Cancer Driver No 125 0.293 40 8 0.2 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:0045595 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 GO:0045595 Not Cancer Driver No 61 0.111 114 9 0.079 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0045595 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTCH2 PTCH2 Q9Y6C5 Protein patched homolog 2 chr1 GO:0045595 Not Cancer Driver No 159 0.132 130 15 0.115 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0045595 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0045595 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0045595 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTHLH_ENST00000539239 PTHLH P12272 Parathyroid hormone-related protein chr12 GO:0045595 Not Cancer Driver No 44 0.249 132 40 0.303 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0045595 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0045595 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTN PTN P21246 Pleiotrophin chr7 GO:0045595 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0045595 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0045595 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0045595 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0045595 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0045595 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRQ_ENST00000616559 PTPRQ Q9UMZ3 Phosphatidylinositol phosphatase PTPRQ chr12 GO:0045595 Not Cancer Driver No 143 0.061 362 22 0.061 1
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0045595 Not Cancer Driver No 250 0.128 829 111 0.134 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0045595 Not Cancer Driver No 480 0.207 978 216 0.221 0
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:0045595 Not Cancer Driver No 27 0.087 161 14 0.087 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 GO:0045595 Not Cancer Driver No 73 0.11 162 17 0.105 1
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0045595 Not Cancer Driver No 51 0.102 186 22 0.118 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0045595 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0045595 Not Cancer Driver No 23 0.102 59 4 0.068 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0045595 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 GO:0045595 Not Cancer Driver No 24 0.125 0 0 0.0 4
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0045595 Census, Compendium Yes 89 0.137 169 38 0.225 22
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0045595 Not Cancer Driver No 118 0.224 85 23 0.271 6
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0045595 Not Cancer Driver No 18 0.103 34 6 0.176 0
RANBP3L_ENST00000296604 RANBP3L Q86VV4 Ran-binding protein 3-like chr5 GO:0045595 Not Cancer Driver No 71 0.153 185 33 0.178 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0045595 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0045595 Not Cancer Driver No 216 0.144 803 116 0.144 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0045595 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0045595 Not Cancer Driver No 82 0.181 164 24 0.146 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0045595 Not Cancer Driver No 16 0.098 14 2 0.143 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0045595 Not Cancer Driver No 25 0.152 7 1 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0045595 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0045595 Not Cancer Driver No 90 0.276 126 44 0.349 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0045595 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBFOX1_ENST00000550418 RBFOX1 Q9NWB1 RNA binding protein fox-1 homolog 1 chr16 GO:0045595 Compendium Yes 179 0.451 181 89 0.492 0
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 GO:0045595 Compendium Yes 44 0.113 173 22 0.127 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0045595 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0045595 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM38 RBM38 Q9H0Z9 RNA-binding protein 38 chr20 GO:0045595 Compendium Yes 33 0.138 50 4 0.08 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:0045595 Not Cancer Driver No 40 0.11 129 12 0.093 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0045595 Not Cancer Driver No 49 0.098 151 19 0.126 2
RBPMS2 RBPMS2 Q6ZRY4 RNA-binding protein with multiple splicing 2 chr15 GO:0045595 Not Cancer Driver No 24 0.115 55 4 0.073 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0045595 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0045595 Not Cancer Driver No 128 0.107 703 81 0.115 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0045595 Not Cancer Driver No 63 0.121 194 27 0.139 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 GO:0045595 Not Cancer Driver No 47 0.097 324 28 0.086 0
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0045595 Not Cancer Driver No 115 0.118 9 2 0.222 0
REG3A_ENST00000305165 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0045595 Not Cancer Driver No 93 0.531 19 10 0.526 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0045595 Not Cancer Driver No 81 0.463 17 4 0.235 0
RELN RELN P78509 Reelin chr7 GO:0045595 Not Cancer Driver No 761 0.22 107 19 0.178 7
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0045595 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0045595 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFLNA_ENST00000546355 RFLNA Q6ZTI6 Refilin-A chr12 GO:0045595 Not Cancer Driver No 23 0.106 122 8 0.066 0
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 GO:0045595 Not Cancer Driver No 113 0.151 308 41 0.133 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0045595 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0045595 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0045595 Not Cancer Driver No 68 0.332 5 4 0.8 0
RHEB RHEB Q15382 GTP-binding protein Rheb chr7 GO:0045595 Not Cancer Driver No 30 0.163 0 0 0.0 0
RHEX RHEX Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein chr1 GO:0045595 Not Cancer Driver No 35 0.203 116 27 0.233 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0045595 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIOX1 RIOX1 Q9H6W3 Ribosomal oxygenase 1 chr14 GO:0045595 Not Cancer Driver No 52 0.081 215 15 0.07 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0045595 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0045595 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0045595 Not Cancer Driver No 131 0.123 421 76 0.181 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0045595 Not Cancer Driver No 19 0.084 54 4 0.074 0
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 GO:0045595 Not Cancer Driver No 108 0.133 455 63 0.138 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0045595 Not Cancer Driver No 86 0.136 168 26 0.155 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0045595 Not Cancer Driver No 44 0.139 33 2 0.061 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0045595 Compendium Yes 91 0.133 601 87 0.145 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0045595 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0045595 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0045595 Not Cancer Driver No 203 0.215 299 71 0.237 5
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0045595 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 GO:0045595 Not Cancer Driver No 107 0.228 87 22 0.253 1
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0045595 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0045595 Not Cancer Driver No 15 0.103 61 3 0.049 23
RRAS RRAS P10301 Ras-related protein R-Ras chr19 GO:0045595 Not Cancer Driver No 25 0.115 71 6 0.085 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0045595 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0045595 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0045595 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0045595 Not Cancer Driver No 75 0.16 204 29 0.142 0
RUNX1T1_ENST00000614812 RUNX1T1 Q06455 Protein CBFA2T1 chr8 GO:0045595 Census, Compendium Yes 292 0.483 469 229 0.488 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0045595 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0045595 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0045595 Not Cancer Driver No 59 0.142 331 45 0.136 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0045595 Not Cancer Driver No 55 0.091 85 4 0.047 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0045595 Not Cancer Driver No 11 0.113 3 1 0.333 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0045595 Not Cancer Driver No 38 0.108 16 3 0.188 2
S1PR3 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0045595 Not Cancer Driver No 69 0.183 28 4 0.143 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0045595 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0045595 Not Cancer Driver No 59 0.155 327 49 0.15 0
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 GO:0045595 Not Cancer Driver No 42 0.11 243 17 0.07 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0045595 Not Cancer Driver No 100 0.14 170 35 0.206 0
SCUBE3 SCUBE3 Q8IX30 Signal peptide, CUB and EGF-like domain-containing protein 3 chr6 GO:0045595 Not Cancer Driver No 131 0.132 110 17 0.155 2
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0045595 Not Cancer Driver No 39 0.131 17 2 0.118 0
SDHAF2 SDHAF2 Q9NX18 Succinate dehydrogenase assembly factor 2, mitochondrial chr11 GO:0045595 Census Yes 29 0.175 22 5 0.227 1
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0045595 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 GO:0045595 Not Cancer Driver No 46 0.061 145 8 0.055 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0045595 Not Cancer Driver No 136 0.181 111 23 0.207 0
SEMA3D SEMA3D O95025 Semaphorin-3D chr7 GO:0045595 Not Cancer Driver No 191 0.246 101 44 0.436 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0045595 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0045595 Not Cancer Driver No 114 0.145 194 27 0.139 0
SEMA3G SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0045595 Not Cancer Driver No 104 0.133 206 28 0.136 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0045595 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0045595 Not Cancer Driver No 94 0.112 107 17 0.159 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0045595 Not Cancer Driver No 111 0.133 149 27 0.181 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0045595 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA4F SEMA4F O95754 Semaphorin-4F chr2 GO:0045595 Not Cancer Driver No 113 0.147 140 16 0.114 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0045595 Not Cancer Driver No 95 0.113 285 30 0.105 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0045595 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0045595 Not Cancer Driver No 229 0.199 162 16 0.099 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0045595 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0045595 Not Cancer Driver No 77 0.087 340 26 0.076 0
SEMA6C SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0045595 Not Cancer Driver No 116 0.125 411 27 0.066 0
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0045595 Not Cancer Driver No 212 0.198 475 99 0.208 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0045595 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0045595 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0045595 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0045595 Not Cancer Driver No 62 0.156 0 0 0.0 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 GO:0045595 Not Cancer Driver No 223 0.131 1327 188 0.142 5
SETD3 SETD3 Q86TU7 Actin-histidine N-methyltransferase chr14 GO:0045595 Not Cancer Driver No 73 0.123 140 24 0.171 0
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0045595 Not Cancer Driver No 27 0.109 75 9 0.12 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0045595 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0045595 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0045595 Census Yes 81 0.234 68 22 0.324 0
SGPP1 SGPP1 Q9BX95 Sphingosine-1-phosphate phosphatase 1 chr14 GO:0045595 Not Cancer Driver No 48 0.109 116 1 0.009 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 GO:0045595 Not Cancer Driver No 109 0.123 586 72 0.123 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0045595 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0045595 Not Cancer Driver No 67 0.202 200 40 0.2 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0045595 Census Yes 68 0.108 470 52 0.111 0
SIGLEC15 SIGLEC15 Q6ZMC9 Sialic acid-binding Ig-like lectin 15 chr18 GO:0045595 Not Cancer Driver No 27 0.082 99 15 0.152 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0045595 Not Cancer Driver No 80 0.102 330 30 0.091 3
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 GO:0045595 Not Cancer Driver No 24 0.109 108 10 0.093 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0045595 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0045595 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0045595 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX2 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0045595 Census Yes 53 0.182 151 21 0.139 0
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0045595 Not Cancer Driver No 99 0.127 460 58 0.126 0
SKI SKI P12755 Ski oncogene chr1 GO:0045595 Census Yes 44 0.06 432 26 0.06 14
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0045595 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0045595 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC45A3 SLC45A3 Q96JT2 Solute carrier family 45 member 3 chr1 GO:0045595 Census, Compendium Yes 75 0.136 25 6 0.24 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0045595 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC4A11_ENST00000539553 SLC4A11 Q8NBS3 Solute carrier family 4 member 11 chr20 GO:0045595 Not Cancer Driver No 159 0.182 69 10 0.145 42
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0045595 Not Cancer Driver No 68 0.127 80 16 0.2 0
SLIT1 SLIT1 O75093 Slit homolog 1 protein chr10 GO:0045595 Not Cancer Driver No 221 0.144 36 1 0.028 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0045595 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0045595 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0045595 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0045595 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0045595 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0045595 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0045595 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 GO:0045595 Not Cancer Driver No 54 0.116 352 46 0.131 0
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:0045595 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0045595 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMOC1_ENST00000381280 SMOC1 Q9H4F8 SPARC-related modular calcium-binding protein 1 chr14 GO:0045595 Not Cancer Driver No 81 0.187 195 47 0.241 3
SMYD1 SMYD1 Q8NB12 Histone-lysine N-methyltransferase SMYD1 chr2 GO:0045595 Not Cancer Driver No 116 0.237 31 9 0.29 0
SMYD5 SMYD5 Q6GMV2 Histone-lysine N-trimethyltransferase SMYD5 chr2 GO:0045595 Not Cancer Driver No 60 0.144 50 6 0.12 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0045595 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0045595 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0045595 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0045595 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0045595 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0045595 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0045595 Not Cancer Driver No 374 0.169 87 10 0.115 0
SORT1 SORT1 Q99523 Sortilin chr1 GO:0045595 Not Cancer Driver No 69 0.083 110 2 0.018 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0045595 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0045595 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOSTDC1 SOSTDC1 Q6X4U4 Sclerostin domain-containing protein 1 chr7 GO:0045595 Not Cancer Driver No 22 0.107 72 3 0.042 0
SOX1 SOX1 O00570 Transcription factor SOX-1 chr13 GO:0045595 Not Cancer Driver No 26 0.066 304 25 0.082 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0045595 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0045595 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:0045595 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0045595 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0045595 Compendium Yes 81 0.196 378 59 0.156 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0045595 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 GO:0045595 Not Cancer Driver No 182 0.239 665 162 0.244 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 GO:0045595 Not Cancer Driver No 130 0.157 744 118 0.159 0
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0045595 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0045595 Compendium Yes 86 0.169 495 82 0.166 18
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 GO:0045595 Not Cancer Driver No 63 0.146 332 44 0.133 0
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 GO:0045595 Not Cancer Driver No 112 0.168 396 68 0.172 1
SPDEF SPDEF O95238 SAM pointed domain-containing Ets transcription factor chr6 GO:0045595 Not Cancer Driver No 47 0.14 110 24 0.218 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0045595 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0045595 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPINT1 SPINT1 O43278 Kunitz-type protease inhibitor 1 chr15 GO:0045595 Not Cancer Driver No 63 0.119 75 12 0.16 0
SPOCK2_ENST00000317376 SPOCK2 Q92563 Testican-2 chr10 GO:0045595 Not Cancer Driver No 48 0.113 113 8 0.071 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0045595 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0045595 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0045595 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:0045595 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0045595 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0045595 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0045595 Not Cancer Driver No 34 0.114 134 20 0.149 7
SRF SRF P11831 Serum response factor chr6 GO:0045595 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 GO:0045595 Not Cancer Driver No 69 0.201 259 49 0.189 0
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:0045595 Census Yes 53 0.134 356 48 0.135 0
SS18L2 SS18L2 Q9UHA2 SS18-like protein 2 chr3 GO:0045595 Not Cancer Driver No 4 0.052 7 1 0.143 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 GO:0045595 Not Cancer Driver No 62 0.106 64 5 0.078 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0045595 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0045595 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0045595 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0045595 Not Cancer Driver No 68 0.119 486 54 0.111 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0045595 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0045595 Not Cancer Driver No 70 0.144 231 30 0.13 0
SUCO_ENST00000263688 SUCO Q9UBS9 SUN domain-containing ossification factor chr1 GO:0045595 Not Cancer Driver No 164 0.131 785 99 0.126 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0045595 Census Yes 55 0.114 199 19 0.095 2
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 GO:0045595 Not Cancer Driver No 76 0.259 15 5 0.333 0
SULT2B1 SULT2B1 O00204 Sulfotransferase 2B1 chr19 GO:0045595 Not Cancer Driver No 42 0.115 100 11 0.11 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 GO:0045595 Not Cancer Driver No 222 0.129 761 107 0.141 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 GO:0045595 Census, Compendium Yes 83 0.112 483 46 0.095 3
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0045595 Not Cancer Driver No 31 0.088 221 22 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0045595 Census Yes 96 0.151 131 27 0.206 5
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0045595 Not Cancer Driver No 153 0.114 830 90 0.108 2
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0045595 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0045595 Not Cancer Driver No 111 0.261 107 41 0.383 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0045595 Not Cancer Driver No 22 0.068 27 1 0.037 0
TAF8 TAF8 Q7Z7C8 Transcription initiation factor TFIID subunit 8 chr6 GO:0045595 Not Cancer Driver No 35 0.113 255 30 0.118 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0045595 Census Yes 54 0.163 305 53 0.174 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0045595 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBX19 TBX19 O60806 T-box transcription factor TBX19 chr1 GO:0045595 Not Cancer Driver No 85 0.19 233 39 0.167 1
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0045595 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0045595 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0045595 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0045595 Census, Compendium Yes 123 0.166 352 57 0.162 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0045595 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0045595 Not Cancer Driver No 44 0.101 253 25 0.099 0
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0045595 Not Cancer Driver No 19 0.095 134 4 0.03 0
TCF23 TCF23 Q7RTU1 Transcription factor 23 chr2 GO:0045595 Not Cancer Driver No 45 0.21 156 33 0.212 0
TCFL5 TCFL5 Q9UL49 Transcription factor-like 5 protein chr20 GO:0045595 Not Cancer Driver No 51 0.102 327 29 0.089 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0045595 Compendium Yes 68 0.082 102 6 0.059 5
TCP11_ENST00000512012 TCP11 Q8WWU5 T-complex protein 11 homolog chr6 GO:0045595 Not Cancer Driver No 78 0.155 112 13 0.116 0
TCTA TCTA P57738 T-cell leukemia translocation-altered gene protein chr3 GO:0045595 Not Cancer Driver No 13 0.126 34 3 0.088 0
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 GO:0045595 Not Cancer Driver No 66 0.148 220 31 0.141 0
TENM4 TENM4 Q6N022 Teneurin-4 chr11 GO:0045595 Not Cancer Driver No 492 0.178 498 63 0.127 3
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 GO:0045595 Not Cancer Driver No 43 0.097 0 0 0.0 0
TENT5C TENT5C Q5VWP2 Terminal nucleotidyltransferase 5C chr1 GO:0045595 Census Yes 65 0.166 1 0 0.0 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0045595 Census Yes 110 0.097 212 16 0.075 31
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0045595 Not Cancer Driver No 31 0.145 73 6 0.082 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0045595 Not Cancer Driver No 63 0.101 339 35 0.103 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0045595 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0045595 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0045595 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFE3 TFE3 P19532 Transcription factor E3 chrX GO:0045595 Census Yes 92 0.16 524 84 0.16 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0045595 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0045595 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0045595 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0045595 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0045595 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0045595 Census, Compendium Yes 106 0.187 60 16 0.267 25
THPO THPO P40225 Thrombopoietin chr3 GO:0045595 Not Cancer Driver No 63 0.178 163 25 0.153 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0045595 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0045595 Not Cancer Driver No 370 0.233 810 194 0.24 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0045595 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0045595 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0045595 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0045595 Not Cancer Driver No 141 0.137 35 3 0.086 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 GO:0045595 Not Cancer Driver No 24 0.085 220 15 0.068 0
TMEM100 TMEM100 Q9NV29 Transmembrane protein 100 chr17 GO:0045595 Not Cancer Driver No 29 0.216 0 0 0.0 0
TMEM119 TMEM119 Q4V9L6 Transmembrane protein 119 chr12 GO:0045595 Not Cancer Driver No 59 0.208 195 47 0.241 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:0045595 Not Cancer Driver No 188 0.117 448 47 0.105 0
TMEM176A_ENST00000004103 TMEM176A Q96HP8 Transmembrane protein 176A chr7 GO:0045595 Not Cancer Driver No 56 0.238 25 4 0.16 0
TMEM176B_ENST00000429904 TMEM176B Q3YBM2 Transmembrane protein 176B chr7 GO:0045595 Not Cancer Driver No 62 0.23 33 8 0.242 0
TMEM178A TMEM178A Q8NBL3 Transmembrane protein 178A chr2 GO:0045595 Not Cancer Driver No 52 0.175 40 2 0.05 0
TMEM182 TMEM182 Q6ZP80 Transmembrane protein 182 chr2 GO:0045595 Not Cancer Driver No 37 0.162 0 0 0.0 0
TMEM64 TMEM64 Q6YI46 Transmembrane protein 64 chr8 GO:0045595 Not Cancer Driver No 33 0.087 32 0 0.0 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0045595 Not Cancer Driver No 39 0.173 27 3 0.111 2
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045595 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0045595 Not Cancer Driver No 62 0.224 13 5 0.385 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0045595 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0045595 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFRSF21 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0045595 Not Cancer Driver No 98 0.15 280 46 0.164 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0045595 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0045595 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0045595 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0045595 Not Cancer Driver No 32 0.126 39 4 0.103 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0045595 Not Cancer Driver No 426 0.328 637 231 0.363 0
TNR TNR Q92752 Tenascin-R chr1 GO:0045595 Not Cancer Driver No 496 0.365 358 128 0.358 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0045595 Not Cancer Driver No 35 0.101 214 18 0.084 0
TOB2 TOB2 Q14106 Protein Tob2 chr22 GO:0045595 Not Cancer Driver No 36 0.105 147 16 0.109 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0045595 Not Cancer Driver No 59 0.097 140 8 0.057 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0045595 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0045595 Not Cancer Driver No 32 0.133 134 20 0.149 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0045595 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0045595 Census, Compendium Yes 229 0.337 398 143 0.359 28
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0045595 Not Cancer Driver No 82 0.129 443 55 0.124 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0045595 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0045595 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0045595 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 GO:0045595 Not Cancer Driver No 64 0.187 43 5 0.116 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0045595 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM11 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 GO:0045595 Not Cancer Driver No 58 0.124 132 14 0.106 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0045595 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0045595 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0045595 Not Cancer Driver No 115 0.152 173 30 0.173 0
TRIM58 TRIM58 Q8NG06 E3 ubiquitin-protein ligase TRIM58 chr1 GO:0045595 Not Cancer Driver No 194 0.399 84 41 0.488 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0045595 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0045595 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRIM72 TRIM72 Q6ZMU5 Tripartite motif-containing protein 72 chr16 GO:0045595 Not Cancer Driver No 54 0.113 69 14 0.203 0
TRIO TRIO O75962 Triple functional domain protein chr5 GO:0045595 Not Cancer Driver No 400 0.129 1052 118 0.112 10
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0045595 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 GO:0045595 Not Cancer Driver No 71 0.122 176 27 0.153 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0045595 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0045595 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPS1_ENST00000220888 TRPS1 Q9UHF7 Zinc finger transcription factor Trps1 chr8 GO:0045595 Not Cancer Driver No 348 0.272 800 216 0.27 7
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0045595 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0045595 Not Cancer Driver No 105 0.137 175 23 0.131 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0045595 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0045595 Not Cancer Driver No 53 0.15 44 6 0.136 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0045595 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0045595 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTPA TTPA P49638 Alpha-tocopherol transfer protein chr8 GO:0045595 Not Cancer Driver No 53 0.191 20 1 0.05 7
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0045595 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0045595 Not Cancer Driver No 23 0.114 132 11 0.083 7
TWIST2 TWIST2 Q8WVJ9 Twist-related protein 2 chr2 GO:0045595 Not Cancer Driver No 11 0.069 90 2 0.022 4
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0045595 Not Cancer Driver No 27 0.121 19 3 0.158 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0045595 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 GO:0045595 Not Cancer Driver No 86 0.133 73 6 0.082 0
UCMA UCMA Q8WVF2 Unique cartilage matrix-associated protein chr10 GO:0045595 Not Cancer Driver No 33 0.239 96 22 0.229 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0045595 Not Cancer Driver No 109 0.137 141 24 0.17 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0045595 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0045595 Not Cancer Driver No 132 0.127 519 84 0.162 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0045595 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNCX UNCX A6NJT0 Homeobox protein unc-4 homolog chr7 GO:0045595 Not Cancer Driver No 28 0.053 410 17 0.041 0
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:0045595 Not Cancer Driver No 10 0.079 41 1 0.024 0
USF3 USF3 Q68DE3 Basic helix-loop-helix domain-containing protein USF3 chr3 GO:0045595 Not Cancer Driver No 286 0.127 2015 259 0.129 0
USH2A USH2A O75445 Usherin chr1 GO:0045595 Not Cancer Driver No 1503 0.289 773 235 0.304 70
VASN VASN Q6EMK4 Vasorin chr16 GO:0045595 Not Cancer Driver No 37 0.055 233 8 0.034 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0045595 Not Cancer Driver No 36 0.108 234 25 0.107 1
VCL VCL P18206 Vinculin chr10 GO:0045595 Not Cancer Driver No 114 0.101 673 80 0.119 2
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0045595 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0045595 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0045595 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEZF1 VEZF1 Q14119 Vascular endothelial zinc finger 1 chr17 GO:0045595 Not Cancer Driver No 56 0.107 332 32 0.096 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0045595 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0045595 Not Cancer Driver No 52 0.167 135 19 0.141 0
VSTM2A_ENST00000407838 VSTM2A Q8TAG5 V-set and transmembrane domain-containing protein 2A chr7 GO:0045595 Not Cancer Driver No 87 0.369 121 42 0.347 0
WDFY2 WDFY2 Q96P53 WD repeat and FYVE domain-containing protein 2 chr13 GO:0045595 Not Cancer Driver No 49 0.122 20 2 0.1 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0045595 Not Cancer Driver No 66 0.109 30 7 0.233 2
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 GO:0045595 Not Cancer Driver No 25 0.082 7 1 0.143 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0045595 Not Cancer Driver No 181 0.119 792 100 0.126 5
WDR63 DNAI3 Q8IWG1 Dynein axonemal intermediate chain 3 chr1 GO:0045595 Not Cancer Driver No 129 0.145 210 31 0.148 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0045595 Not Cancer Driver No 104 0.183 345 65 0.188 1
WIF1 WIF1 Q9Y5W5 Wnt inhibitory factor 1 chr12 GO:0045595 Census Yes 74 0.195 30 3 0.1 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0045595 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0045595 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0045595 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0045595 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0045595 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0045595 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0045595 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0045595 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT9A WNT9A O14904 Protein Wnt-9a chr1 GO:0045595 Not Cancer Driver No 74 0.203 44 11 0.25 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0045595 Not Cancer Driver No 47 0.132 11 4 0.364 0
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0045595 Census Yes 41 0.102 387 41 0.106 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0045595 Not Cancer Driver No 19 0.073 169 9 0.053 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0045595 Not Cancer Driver No 279 0.209 134 24 0.179 1
XKR8 XKR8 Q9H6D3 XK-related protein 8 chr1 GO:0045595 Not Cancer Driver No 34 0.086 4 0 0.0 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0045595 Not Cancer Driver No 66 0.108 140 12 0.086 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0045595 Not Cancer Driver No 51 0.101 489 49 0.1 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0045595 Not Cancer Driver No 41 0.127 312 41 0.131 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0045595 Not Cancer Driver No 67 0.116 376 44 0.117 0
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0045595 Not Cancer Driver No 15 0.061 55 3 0.055 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0045595 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZADH2 PTGR3 Q8N4Q0 Prostaglandin reductase 3 chr18 GO:0045595 Not Cancer Driver No 42 0.111 0 0 0.0 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0045595 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBED2 ZBED2 Q9BTP6 Zinc finger BED domain-containing protein 2 chr3 GO:0045595 Not Cancer Driver No 62 0.284 172 39 0.227 0
ZBED6 ZBED6 P86452 Zinc finger BED domain-containing protein 6 chr1 GO:0045595 Not Cancer Driver No 3 0.003 278 2 0.007 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0045595 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0045595 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB46_ENST00000302995 ZBTB46 Q86UZ6 Zinc finger and BTB domain-containing protein 46 chr20 GO:0045595 Not Cancer Driver No 115 0.195 301 68 0.226 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0045595 Compendium Yes 103 0.191 353 70 0.198 0
ZBTB7C_ENST00000590800 ZBTB7C A1YPR0 Zinc finger and BTB domain-containing protein 7C chr18 GO:0045595 Not Cancer Driver No 91 0.147 249 40 0.161 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0045595 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0045595 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZDHHC21 ZDHHC21 Q8IVQ6 Palmitoyltransferase ZDHHC21 chr9 GO:0045595 Not Cancer Driver No 34 0.128 0 0 0.0 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0045595 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0045595 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0045595 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0045595 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0045595 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:0045595 Not Cancer Driver No 50 0.05 772 27 0.035 0
ZFPM2 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 GO:0045595 Not Cancer Driver No 374 0.325 659 233 0.354 8
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 GO:0045595 Not Cancer Driver No 45 0.109 140 22 0.157 1
ZHX3_ENST00000559234 ZHX3 Q9H4I2 Zinc fingers and homeoboxes protein 3 chr20 GO:0045595 Not Cancer Driver No 111 0.116 617 73 0.118 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:0045595 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 GO:0045595 Not Cancer Driver No 44 0.061 628 37 0.059 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0045595 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0045595 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0045595 Not Cancer Driver No 114 0.201 91 19 0.209 0
ZNF683 ZNF683 Q8IZ20 Tissue-resident T-cell transcription regulator protein ZNF683 chr1 GO:0045595 Not Cancer Driver No 103 0.197 202 32 0.158 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0045595 Not Cancer Driver No 26 0.044 415 14 0.034 0
ZNF750 ZNF750 Q32MQ0 Zinc finger protein 750 chr17 GO:0045595 Not Cancer Driver No 95 0.131 587 72 0.123 0