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Total number of protein in "GO:0043434" GO term:  125

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0043434 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0043434 Not Cancer Driver No 419 0.335 215 38 0.177 0
AGT AGT P01019 Angiotensinogen chr1 GO:0043434 Not Cancer Driver No 85 0.179 33 10 0.303 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0043434 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0043434 Not Cancer Driver No 59 0.171 61 12 0.197 0
AREG AREG P15514 Amphiregulin chr4 GO:0043434 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0043434 Not Cancer Driver No 41 0.127 83 12 0.145 9
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0043434 Not Cancer Driver No 65 0.158 63 8 0.127 86
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0043434 Not Cancer Driver No 91 0.211 69 18 0.261 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0043434 Census Yes 174 0.139 397 59 0.149 6
BSG BSG P35613 Basigin chr19 GO:0043434 Not Cancer Driver No 43 0.112 123 17 0.138 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0043434 Census, Compendium Yes 21 0.123 19 0 0.0 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0043434 Census Yes 32 0.203 7 2 0.286 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0043434 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0043434 Not Cancer Driver No 45 0.104 186 19 0.102 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0043434 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0043434 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 GO:0043434 Not Cancer Driver No 37 0.185 43 4 0.093 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0043434 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0043434 Census Yes 402 0.274 1182 337 0.285 103
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0043434 Not Cancer Driver No 368 0.245 73 22 0.301 140
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0043434 Census Yes 25 0.076 277 23 0.083 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0043434 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0043434 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:0043434 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0043434 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0043434 Not Cancer Driver No 76 0.13 91 5 0.055 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0043434 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0043434 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0043434 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 GO:0043434 Not Cancer Driver No 65 0.2 35 8 0.229 2
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0043434 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:0043434 Census, Compendium Yes 64 0.185 0 0 0.0 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0043434 Not Cancer Driver No 102 0.114 485 61 0.126 4
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0043434 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0043434 Not Cancer Driver No 62 0.145 21 6 0.286 2
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0043434 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0043434 Not Cancer Driver No 104 0.143 311 39 0.125 0
EIF2B1 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 GO:0043434 Not Cancer Driver No 33 0.108 0 0 0.0 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0043434 Not Cancer Driver No 40 0.114 83 11 0.133 9
EIF2B3 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 GO:0043434 Not Cancer Driver No 54 0.119 28 9 0.321 5
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 GO:0043434 Not Cancer Driver No 57 0.109 212 29 0.137 7
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 GO:0043434 Not Cancer Driver No 76 0.105 179 16 0.089 29
EREG EREG O14944 Proepiregulin chr4 GO:0043434 Not Cancer Driver No 26 0.154 10 3 0.3 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0043434 Not Cancer Driver No 74 0.159 50 7 0.14 108
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0043434 Not Cancer Driver No 466 0.162 110 16 0.145 360
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0043434 Not Cancer Driver No 37 0.177 109 24 0.22 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:0043434 Not Cancer Driver No 16 0.034 56 2 0.036 4
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0043434 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0043434 Not Cancer Driver No 35 0.229 68 16 0.235 0
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0043434 Not Cancer Driver No 34 0.15 0 0 0.0 46
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0043434 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:0043434 Not Cancer Driver No 124 0.224 63 14 0.222 0
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0043434 Not Cancer Driver No 52 0.147 11 3 0.273 0
GNRHR GNRHR P30968 Gonadotropin-releasing hormone receptor chr4 GO:0043434 Not Cancer Driver No 40 0.122 15 1 0.067 14
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:0043434 Not Cancer Driver No 57 0.153 12 0 0.0 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0043434 Not Cancer Driver No 92 0.181 29 4 0.138 19
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0043434 Not Cancer Driver No 59 0.112 335 37 0.11 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0043434 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0043434 Not Cancer Driver No 27 0.099 112 17 0.152 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0043434 Not Cancer Driver No 161 0.13 1072 133 0.124 2
JUND JUND P17535 Transcription factor JunD chr19 GO:0043434 Not Cancer Driver No 21 0.061 313 19 0.061 0
KL KL Q9UEF7 Klotho chr13 GO:0043434 Not Cancer Driver No 175 0.173 104 5 0.048 1
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0043434 Not Cancer Driver No 181 0.259 12 8 0.667 25
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0043434 Not Cancer Driver No 206 0.128 255 30 0.118 5
LTA4H LTA4H P09960 Leukotriene A-4 hydrolase chr12 GO:0043434 Not Cancer Driver No 59 0.097 39 6 0.154 0
MC4R MC4R P32245 Melanocortin receptor 4 chr18 GO:0043434 Not Cancer Driver No 57 0.172 2 0 0.0 29
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0043434 Not Cancer Driver No 25 0.104 207 22 0.106 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043434 Census, Compendium Yes 80 0.182 299 46 0.154 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0043434 Not Cancer Driver No 92 0.169 285 39 0.137 12
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0043434 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0043434 Not Cancer Driver No 104 0.107 344 38 0.11 0
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0043434 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0043434 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0043434 Census Yes 83 0.133 298 37 0.124 0
NUDC NUDC Q9Y266 Nuclear migration protein nudC chr1 GO:0043434 Not Cancer Driver No 36 0.109 235 29 0.123 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0043434 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0043434 Not Cancer Driver No 46 0.118 18 0 0.0 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0043434 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0043434 Not Cancer Driver No 139 0.185 336 61 0.182 2
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0043434 Not Cancer Driver No 81 0.172 48 11 0.229 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0043434 Not Cancer Driver No 144 0.192 56 7 0.125 30
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0043434 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0043434 Not Cancer Driver No 313 0.257 481 104 0.216 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0043434 Not Cancer Driver No 86 0.11 115 10 0.087 2
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0043434 Not Cancer Driver No 50 0.187 198 38 0.192 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0043434 Compendium Yes 79 0.117 43 9 0.209 0
PRLH PRLH P81277 Prolactin-releasing peptide chr2 GO:0043434 Not Cancer Driver No 10 0.115 28 3 0.107 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0043434 Not Cancer Driver No 105 0.174 30 5 0.167 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0043434 Not Cancer Driver No 65 0.111 159 17 0.107 0
REG1A REG1A P05451 Lithostathine-1-alpha chr2 GO:0043434 Not Cancer Driver No 97 0.584 9 5 0.556 0
REG1B REG1B P48304 Lithostathine-1-beta chr2 GO:0043434 Not Cancer Driver No 91 0.548 14 8 0.571 0
REG3A_ENST00000305165 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0043434 Not Cancer Driver No 93 0.531 19 10 0.526 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0043434 Not Cancer Driver No 81 0.463 17 4 0.235 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0043434 Compendium Yes 75 0.136 400 48 0.12 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0043434 Not Cancer Driver No 132 0.132 645 80 0.124 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0043434 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0043434 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0043434 Not Cancer Driver No 45 0.086 226 26 0.115 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0043434 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0043434 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0043434 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0043434 Not Cancer Driver No 92 0.144 46 8 0.174 9
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0043434 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0043434 Not Cancer Driver No 48 0.189 0 0 0.0 21
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0043434 Not Cancer Driver No 127 0.111 528 64 0.121 4
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0043434 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 GO:0043434 Not Cancer Driver No 90 0.106 178 22 0.124 2
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0043434 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT4_ENST00000358470 STAT4 Q14765 Signal transducer and activator of transcription 4 chr2 GO:0043434 Not Cancer Driver No 154 0.206 143 36 0.252 0
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 GO:0043434 Not Cancer Driver No 89 0.112 125 14 0.112 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0043434 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0043434 Census, Compendium Yes 106 0.125 325 44 0.135 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0043434 Not Cancer Driver No 71 0.235 112 29 0.259 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0043434 Census, Compendium Yes 75 0.173 135 14 0.104 9
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0043434 Not Cancer Driver No 31 0.088 221 22 0.1 0
TFF1 TFF1 P04155 Trefoil factor 1 chr21 GO:0043434 Not Cancer Driver No 9 0.107 0 0 0.0 0
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0043434 Not Cancer Driver No 129 0.152 268 41 0.153 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0043434 Not Cancer Driver No 61 0.116 149 21 0.141 38
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0043434 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0043434 Not Cancer Driver No 30 0.134 8 2 0.25 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0043434 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0043434 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0043434 Census Yes 128 0.168 38 9 0.237 39
UMODL1_ENST00000408910 UMODL1 Q5DID0 Uromodulin-like 1 chr21 GO:0043434 Not Cancer Driver No 191 0.145 249 29 0.116 0