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Total number of protein in "GO:0030856" GO term:  140

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0030856 Not Cancer Driver No 511 0.197 136 23 0.169 14
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0030856 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0030856 Not Cancer Driver No 106 0.144 439 64 0.146 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0030856 Not Cancer Driver No 120 0.1 500 56 0.112 6
AJAP1 AJAP1 Q9UKB5 Adherens junction-associated protein 1 chr1 GO:0030856 Not Cancer Driver No 103 0.251 271 64 0.236 0
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0030856 Not Cancer Driver No 99 0.146 62 12 0.194 0
APOLD1 APOLD1 Q96LR9 Apolipoprotein L domain-containing protein 1 chr12 GO:0030856 Not Cancer Driver No 23 0.082 22 0 0.0 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0030856 Not Cancer Driver No 34 0.116 12 0 0.0 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0030856 Not Cancer Driver No 33 0.14 182 24 0.132 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0030856 Not Cancer Driver No 63 0.178 327 55 0.168 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0030856 Not Cancer Driver No 31 0.097 254 23 0.091 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0030856 Not Cancer Driver No 14 0.083 163 14 0.086 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0030856 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0030856 Not Cancer Driver No 95 0.185 226 51 0.226 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0030856 Census, Compendium Yes 21 0.123 19 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0030856 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0030856 Census, Compendium Yes 55 0.186 31 25 0.806 0
CD109 CD109 Q6YHK3 CD109 antigen chr6 GO:0030856 Not Cancer Driver No 204 0.141 54 11 0.204 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0030856 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0030856 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0030856 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0030856 Not Cancer Driver No 15 0.109 67 3 0.045 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0030856 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0030856 Not Cancer Driver No 3 0.009 276 2 0.007 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0030856 Not Cancer Driver No 15 0.069 0 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0030856 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0030856 Not Cancer Driver No 71 0.14 79 13 0.165 18
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0030856 Not Cancer Driver No 115 0.159 145 24 0.166 1
DSPP_ENST00000282478 DSPP Q9NZW4 Dentin sialophosphoprotein chr4 GO:0030856 Not Cancer Driver No 208 0.16 1278 206 0.161 8
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0030856 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESRP1_ENST00000642581 ESRP1 Q6NXG1 Epithelial splicing regulatory protein 1 chr8 GO:0030856 Not Cancer Driver No 120 0.176 41 5 0.122 1
ETV2_ENST00000403402 ETV2 O00321 ETS translocation variant 2 chr19 GO:0030856 Not Cancer Driver No 23 0.067 227 15 0.066 0
ETV4_ENST00000591713 ETV4 P43268 ETS translocation variant 4 chr17 GO:0030856 Census, Compendium Yes 44 0.091 319 26 0.082 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0030856 Census, Compendium Yes 120 0.161 284 44 0.155 11
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0030856 Not Cancer Driver No 47 0.157 72 15 0.208 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0030856 Not Cancer Driver No 18 0.062 183 5 0.027 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0030856 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0030856 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0030856 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXJ2 FOXJ2 Q9P0K8 Forkhead box protein J2 chr12 GO:0030856 Not Cancer Driver No 81 0.141 483 65 0.135 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0030856 Not Cancer Driver No 90 0.139 483 65 0.135 2
FRZB FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0030856 Not Cancer Driver No 58 0.178 31 6 0.194 1
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0030856 Census, Compendium Yes 111 0.251 364 87 0.239 2
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0030856 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0030856 Not Cancer Driver No 47 0.223 83 18 0.217 2
GRHL1 GRHL1 Q9NZI5 Grainyhead-like protein 1 homolog chr2 GO:0030856 Not Cancer Driver No 99 0.16 256 36 0.141 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0030856 Not Cancer Driver No 95 0.152 258 43 0.167 2
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0030856 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0030856 Not Cancer Driver No 59 0.159 171 32 0.187 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0030856 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0030856 Not Cancer Driver No 1 0.006 73 0 0.0 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0030856 Not Cancer Driver No 64 0.19 179 26 0.145 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0030856 Not Cancer Driver No 60 0.261 71 15 0.211 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0030856 Not Cancer Driver No 20 0.129 17 6 0.353 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0030856 Not Cancer Driver No 51 0.307 23 6 0.261 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0030856 Census, Compendium Yes 106 0.14 211 31 0.147 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0030856 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0030856 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0030856 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:0030856 Not Cancer Driver No 30 0.17 0 0 0.0 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0030856 Not Cancer Driver No 182 0.149 172 20 0.116 52
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0030856 Not Cancer Driver No 61 0.153 277 50 0.181 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0030856 Census, Compendium Yes 237 0.38 57 12 0.211 0
KIAA1109 KIAA1109 Q2LD37 Transmembrane protein KIAA1109 chr4 GO:0030856 Not Cancer Driver No 688 0.137 2276 312 0.137 0
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0030856 Not Cancer Driver No 46 0.152 72 7 0.097 0
KRT36 KRT36 O76013 Keratin, type I cuticular Ha6 chr17 GO:0030856 Not Cancer Driver No 99 0.212 52 18 0.346 0
KRT84 KRT84 Q9NSB2 Keratin, type II cuticular Hb4 chr12 GO:0030856 Not Cancer Driver No 101 0.168 41 4 0.098 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0030856 Not Cancer Driver No 25 0.124 0 0 0.0 0
MAFF_ENST00000426621 MAFF Q9ULX9 Transcription factor MafF chr22 GO:0030856 Not Cancer Driver No 9 0.055 118 7 0.059 0
MAFG MAFG O15525 Transcription factor MafG chr17 GO:0030856 Not Cancer Driver No 5 0.031 132 5 0.038 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0030856 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0030856 Not Cancer Driver No 8 0.03 247 7 0.028 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0030856 Not Cancer Driver No 129 0.182 124 26 0.21 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0030856 Not Cancer Driver No 27 0.101 168 14 0.083 4
MYCL_ENST00000372816 MYCL P12524 Protein L-Myc chr1 GO:0030856 Census Yes 47 0.129 275 43 0.156 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0030856 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0030856 Not Cancer Driver No 38 0.104 325 34 0.105 0
NKX6-3_ENST00000518699 NKX6-3 A6NJ46 Homeobox protein Nkx-6.3 chr8 GO:0030856 Not Cancer Driver No 7 0.026 164 7 0.043 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0030856 Not Cancer Driver No 13 0.086 11 1 0.091 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0030856 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0030856 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0030856 Not Cancer Driver No 336 0.168 464 79 0.17 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0030856 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0030856 Not Cancer Driver No 57 0.214 67 17 0.254 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0030856 Not Cancer Driver No 29 0.105 139 8 0.058 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0030856 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0030856 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0030856 Census Yes 84 0.187 291 55 0.189 4
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0030856 Not Cancer Driver No 313 0.257 481 104 0.216 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0030856 Not Cancer Driver No 107 0.104 821 89 0.108 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0030856 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX GO:0030856 Not Cancer Driver No 54 0.151 69 3 0.043 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0030856 Not Cancer Driver No 154 0.248 282 70 0.248 2
PROC PROC P04070 Vitamin K-dependent protein C chr2 GO:0030856 Not Cancer Driver No 73 0.158 41 9 0.22 36
PROM1 PROM1 O43490 Prominin-1 chr4 GO:0030856 Not Cancer Driver No 94 0.109 76 9 0.118 3
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0030856 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTCH2 PTCH2 Q9Y6C5 Protein patched homolog 2 chr1 GO:0030856 Not Cancer Driver No 159 0.132 130 15 0.115 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0030856 Not Cancer Driver No 25 0.152 7 1 0.143 0
REG3A_ENST00000305165 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0030856 Not Cancer Driver No 93 0.531 19 10 0.526 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0030856 Not Cancer Driver No 81 0.463 17 4 0.235 0
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 GO:0030856 Not Cancer Driver No 113 0.151 308 41 0.133 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0030856 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0030856 Not Cancer Driver No 145 0.104 732 81 0.111 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0030856 Not Cancer Driver No 38 0.108 16 3 0.188 2
S1PR3 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0030856 Not Cancer Driver No 69 0.183 28 4 0.143 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0030856 Not Cancer Driver No 78 0.194 7 2 0.286 0
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0030856 Not Cancer Driver No 27 0.109 75 9 0.12 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0030856 Census Yes 81 0.234 68 22 0.324 0
SGPP1 SGPP1 Q9BX95 Sphingosine-1-phosphate phosphatase 1 chr14 GO:0030856 Not Cancer Driver No 48 0.109 116 1 0.009 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0030856 Census, Compendium Yes 112 0.142 241 27 0.112 1
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0030856 Compendium Yes 86 0.169 495 82 0.166 18
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0030856 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0030856 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:0030856 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0030856 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0030856 Not Cancer Driver No 46 0.146 169 29 0.172 1
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 GO:0030856 Not Cancer Driver No 69 0.201 259 49 0.189 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0030856 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0030856 Census, Compendium Yes 93 0.118 144 19 0.132 5
SULT2B1 SULT2B1 O00204 Sulfotransferase 2B1 chr19 GO:0030856 Not Cancer Driver No 42 0.115 100 11 0.11 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0030856 Census, Compendium Yes 123 0.166 352 57 0.162 2
TMEM100 TMEM100 Q9NV29 Transmembrane protein 100 chr17 GO:0030856 Not Cancer Driver No 29 0.216 0 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0030856 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0030856 Not Cancer Driver No 58 0.127 111 15 0.135 12
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0030856 Census, Compendium Yes 229 0.337 398 143 0.359 28
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0030856 Not Cancer Driver No 64 0.113 132 11 0.083 0
VCL VCL P18206 Vinculin chr10 GO:0030856 Not Cancer Driver No 114 0.101 673 80 0.119 2
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0030856 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0030856 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEZF1 VEZF1 Q14119 Vascular endothelial zinc finger 1 chr17 GO:0030856 Not Cancer Driver No 56 0.107 332 32 0.096 0
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0030856 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0030856 Not Cancer Driver No 47 0.132 11 4 0.364 0
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0030856 Census Yes 41 0.102 387 41 0.106 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0030856 Not Cancer Driver No 279 0.209 134 24 0.179 1
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0030856 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZBED2 ZBED2 Q9BTP6 Zinc finger BED domain-containing protein 2 chr3 GO:0030856 Not Cancer Driver No 62 0.284 172 39 0.227 0
ZDHHC21 ZDHHC21 Q8IVQ6 Palmitoyltransferase ZDHHC21 chr9 GO:0030856 Not Cancer Driver No 34 0.128 0 0 0.0 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0030856 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0030856 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0030856 Compendium Yes 57 0.169 212 30 0.142 0