Filter in search result
Please select a valid state.

Total number of protein in "GO:0014070" GO term:  621

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0014070 Not Cancer Driver No 260 0.176 144 22 0.153 0
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0014070 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0014070 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0014070 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0014070 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0014070 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABCC9_ENST00000261201 ABCC9 O60706 ATP-binding cassette sub-family C member 9 chr12 GO:0014070 Not Cancer Driver No 368 0.238 132 30 0.227 15
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 GO:0014070 Not Cancer Driver No 75 0.114 21 2 0.095 0
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0014070 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0014070 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0014070 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0014070 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0014070 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0014070 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0014070 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0014070 Not Cancer Driver No 85 0.122 27 1 0.037 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0014070 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0014070 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0014070 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0014070 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0014070 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0014070 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0014070 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0014070 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0014070 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0014070 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0014070 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0014070 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0014070 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0014070 Not Cancer Driver No 49 0.107 48 4 0.083 0
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 GO:0014070 Not Cancer Driver No 182 0.119 143 23 0.161 1
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0014070 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0014070 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0014070 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0014070 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0014070 Census Yes 474 0.121 2281 268 0.117 1
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0014070 Not Cancer Driver No 49 0.152 11 1 0.091 0
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0014070 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0014070 Not Cancer Driver No 80 0.153 184 39 0.212 113
AMH AMH P03971 Muellerian-inhibiting factor chr19 GO:0014070 Not Cancer Driver No 19 0.034 207 4 0.019 9
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0014070 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0014070 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0014070 Not Cancer Driver No 53 0.164 22 4 0.182 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0014070 Not Cancer Driver No 161 0.214 98 26 0.265 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0014070 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0014070 Not Cancer Driver No 146 0.225 455 98 0.215 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0014070 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0014070 Not Cancer Driver No 77 0.194 298 65 0.218 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0014070 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0014070 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0014070 Not Cancer Driver No 34 0.116 12 0 0.0 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0014070 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP8 AQP8 O94778 Aquaporin-8 chr16 GO:0014070 Not Cancer Driver No 49 0.188 0 0 0.0 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0014070 Not Cancer Driver No 75 0.254 12 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0014070 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0014070 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0014070 Not Cancer Driver No 41 0.127 83 12 0.145 9
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0014070 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0014070 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF1 ATF1 P18846 Cyclic AMP-dependent transcription factor ATF-1 chr12 GO:0014070 Census Yes 31 0.114 240 28 0.117 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0014070 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0014070 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0014070 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0014070 Not Cancer Driver No 66 0.119 23 5 0.217 2
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0014070 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0014070 Not Cancer Driver No 105 0.251 68 25 0.368 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0014070 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0014070 Not Cancer Driver No 38 0.18 58 9 0.155 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0014070 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 GO:0014070 Not Cancer Driver No 47 0.12 23 3 0.13 5
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0014070 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0014070 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0014070 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0014070 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0014070 Not Cancer Driver No 45 0.1 190 19 0.1 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0014070 Not Cancer Driver No 13 0.13 21 2 0.095 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0014070 Not Cancer Driver No 69 0.112 83 9 0.108 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0014070 Census Yes 153 0.108 667 70 0.105 8
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0014070 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0014070 Not Cancer Driver No 91 0.211 69 18 0.261 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0014070 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BSG BSG P35613 Basigin chr19 GO:0014070 Not Cancer Driver No 43 0.112 123 17 0.138 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0014070 Census Yes 32 0.203 7 2 0.286 0
CA9 CA9 Q16790 Carbonic anhydrase 9 chr9 GO:0014070 Not Cancer Driver No 72 0.157 274 50 0.182 0
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0014070 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNG4 CACNG4 Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit chr17 GO:0014070 Not Cancer Driver No 51 0.156 71 17 0.239 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0014070 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0014070 Not Cancer Driver No 17 0.114 115 10 0.087 3
CALR CALR P27797 Calreticulin chr19 GO:0014070 Census Yes 45 0.108 245 31 0.127 0
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0014070 Not Cancer Driver No 72 0.134 225 35 0.156 11
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 GO:0014070 Not Cancer Driver No 62 0.102 102 10 0.098 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0014070 Census Yes 32 0.116 62 5 0.081 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0014070 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0014070 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0014070 Census Yes 49 0.118 71 7 0.099 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0014070 Not Cancer Driver No 74 0.185 75 16 0.213 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0014070 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAT CAT P04040 Catalase chr11 GO:0014070 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0014070 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0014070 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0014070 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCDC62 CCDC62 Q6P9F0 Coiled-coil domain-containing protein 62 chr12 GO:0014070 Not Cancer Driver No 104 0.152 344 56 0.163 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0014070 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0014070 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0014070 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0014070 Not Cancer Driver No 107 0.304 0 0 0.0 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0014070 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0014070 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0014070 Not Cancer Driver No 24 0.117 48 8 0.167 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0014070 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0014070 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0014070 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0014070 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0014070 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0014070 Not Cancer Driver No 17 0.102 44 3 0.068 0
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 GO:0014070 Not Cancer Driver No 37 0.185 43 4 0.093 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0014070 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0014070 Not Cancer Driver No 40 0.083 44 2 0.045 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0014070 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0014070 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0014070 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0014070 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0014070 Not Cancer Driver No 92 0.183 23 2 0.087 2
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 GO:0014070 Not Cancer Driver No 25 0.134 7 0 0.0 5
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0014070 Not Cancer Driver No 43 0.196 32 3 0.094 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0014070 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0014070 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0014070 Not Cancer Driver No 40 0.191 0 0 0.0 0
CNGA3 CNGA3 Q16281 Cyclic nucleotide-gated cation channel alpha-3 chr2 GO:0014070 Not Cancer Driver No 183 0.264 217 67 0.309 53
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0014070 Not Cancer Driver No 129 0.273 9 1 0.111 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0014070 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 GO:0014070 Not Cancer Driver No 147 0.198 450 90 0.2 0
CPN1 CPN1 P15169 Carboxypeptidase N catalytic chain chr10 GO:0014070 Not Cancer Driver No 98 0.214 124 27 0.218 1
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0014070 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0014070 Not Cancer Driver No 144 0.186 62 10 0.161 15
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0014070 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRLS1 CRLS1 Q9UJA2 Cardiolipin synthase (CMP-forming) chr20 GO:0014070 Not Cancer Driver No 18 0.06 36 0 0.0 0
CSN1S1 CSN1S1 P47710 Alpha-S1-casein chr4 GO:0014070 Not Cancer Driver No 31 0.168 109 16 0.147 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0014070 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0014070 Census, Compendium Yes 415 0.531 288 301 1.045 14
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0014070 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0014070 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0014070 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0014070 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0014070 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP24A1 CYP24A1 Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial chr20 GO:0014070 Not Cancer Driver No 74 0.144 77 5 0.065 4
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0014070 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0014070 Not Cancer Driver No 109 0.216 48 8 0.167 0
CYP8B1 CYP8B1 Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase chr3 GO:0014070 Not Cancer Driver No 91 0.182 5 1 0.2 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0014070 Not Cancer Driver No 102 0.114 485 61 0.126 4
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0014070 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0014070 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0014070 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0014070 Not Cancer Driver No 118 0.128 61 10 0.164 2
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0014070 Not Cancer Driver No 56 0.059 264 11 0.042 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0014070 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0014070 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0014070 Compendium Yes 182 0.143 331 42 0.127 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0014070 Not Cancer Driver No 118 0.093 692 57 0.082 1
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0014070 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0014070 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0014070 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0014070 Census, Compendium Yes 194 0.213 371 59 0.159 16
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0014070 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0014070 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0014070 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0014070 Not Cancer Driver No 26 0.062 109 0 0.0 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0014070 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSG1 DSG1 Q02413 Desmoglein-1 chr18 GO:0014070 Not Cancer Driver No 250 0.238 496 130 0.262 0
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0014070 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0014070 Not Cancer Driver No 245 0.158 182 25 0.137 3
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0014070 Not Cancer Driver No 43 0.113 39 3 0.077 4
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0014070 Not Cancer Driver No 54 0.257 78 21 0.269 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0014070 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0014070 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0014070 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0014070 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 GO:0014070 Compendium Yes 132 0.136 179 30 0.168 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0014070 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0014070 Not Cancer Driver No 78 0.144 501 72 0.144 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0014070 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0014070 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0014070 Not Cancer Driver No 26 0.12 54 6 0.111 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0014070 Not Cancer Driver No 118 0.306 117 34 0.291 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0014070 Not Cancer Driver No 51 0.119 327 34 0.104 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0014070 Not Cancer Driver No 42 0.107 357 30 0.084 0
ENG ENG P17813 Endoglin chr9 GO:0014070 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPG5 EPG5 Q9HCE0 Ectopic P granules protein 5 homolog chr18 GO:0014070 Not Cancer Driver No 305 0.118 347 46 0.133 2
EPHX1_ENST00000366837 EPHX1 P07099 Epoxide hydrolase 1 chr1 GO:0014070 Not Cancer Driver No 75 0.165 7 3 0.429 0
EPO EPO P01588 Erythropoietin chr7 GO:0014070 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0014070 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0014070 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0014070 Not Cancer Driver No 90 0.17 92 11 0.12 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0014070 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0014070 Census Yes 66 0.113 295 35 0.119 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0014070 Not Cancer Driver No 74 0.159 50 7 0.14 108
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0014070 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0014070 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0014070 Not Cancer Driver No 10 0.052 32 0 0.0 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0014070 Not Cancer Driver No 54 0.152 0 0 0.0 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0014070 Not Cancer Driver No 12 0.065 61 2 0.033 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0014070 Census Yes 103 0.125 245 34 0.139 0
FGF19 FGF19 O95750 Fibroblast growth factor 19 chr11 GO:0014070 Not Cancer Driver No 20 0.093 36 7 0.194 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0014070 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0014070 Census, Compendium Yes 113 0.141 162 28 0.173 0
FIBIN FIBIN Q8TAL6 Fin bud initiation factor homolog chr11 GO:0014070 Not Cancer Driver No 42 0.199 51 12 0.235 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0014070 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0014070 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0014070 Census, Compendium Yes 200 0.201 64 27 0.422 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0014070 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0014070 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOS FOS P01100 Protein c-Fos chr14 GO:0014070 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSB FOSB P53539 Protein FosB chr19 GO:0014070 Not Cancer Driver No 50 0.148 313 44 0.141 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0014070 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0014070 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0014070 Not Cancer Driver No 38 0.088 186 16 0.086 10
FUK FCSK Q8N0W3 L-fucose kinase chr16 GO:0014070 Not Cancer Driver No 102 0.094 26 1 0.038 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0014070 Not Cancer Driver No 86 0.167 28 3 0.107 58
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:0014070 Not Cancer Driver No 58 0.128 103 8 0.078 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0014070 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0014070 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0014070 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0014070 Not Cancer Driver No 188 0.403 19 13 0.684 11
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0014070 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0014070 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0014070 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0014070 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0014070 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDAP1 GDAP1 Q8TB36 Ganglioside-induced differentiation-associated protein 1 chr8 GO:0014070 Not Cancer Driver No 51 0.142 78 14 0.179 11
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0014070 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0014070 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0014070 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0014070 Not Cancer Driver No 35 0.229 68 16 0.235 0
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0014070 Not Cancer Driver No 34 0.15 0 0 0.0 46
GLB1 GLB1 P16278 Beta-galactosidase chr3 GO:0014070 Not Cancer Driver No 72 0.106 54 6 0.111 99
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 GO:0014070 Not Cancer Driver No 152 0.149 112 7 0.062 22
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0014070 Not Cancer Driver No 52 0.147 11 3 0.273 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0014070 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0014070 Not Cancer Driver No 17 0.239 12 3 0.25 0
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0014070 Not Cancer Driver No 41 0.138 72 1 0.014 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0014070 Not Cancer Driver No 56 0.136 35 5 0.143 0
GPBAR1_ENST00000521462 GPBAR1 Q8TDU6 G-protein coupled bile acid receptor 1 chr2 GO:0014070 Not Cancer Driver No 30 0.091 22 4 0.182 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0014070 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0014070 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0014070 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0014070 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR83 GPR83 Q9NYM4 G-protein coupled receptor 83 chr11 GO:0014070 Not Cancer Driver No 93 0.22 32 10 0.312 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0014070 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 GO:0014070 Not Cancer Driver No 83 0.115 261 33 0.126 0
GRAMD1B_ENST00000529750 GRAMD1B Q3KR37 Protein Aster-B chr11 GO:0014070 Not Cancer Driver No 140 0.19 335 69 0.206 0
GRAMD1C GRAMD1C Q8IYS0 Protein Aster-C chr3 GO:0014070 Not Cancer Driver No 103 0.156 205 31 0.151 0
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0014070 Not Cancer Driver No 143 0.164 24 3 0.125 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0014070 Not Cancer Driver No 26 0.119 5 0 0.0 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0014070 Not Cancer Driver No 23 0.18 71 16 0.225 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0014070 Not Cancer Driver No 7 0.083 4 0 0.0 4
HBE1_ENST00000396895 HBE1 P02100 Hemoglobin subunit epsilon chr11 GO:0014070 Not Cancer Driver No 44 0.299 0 0 0.0 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0014070 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0014070 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0014070 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0014070 Not Cancer Driver No 187 0.155 631 58 0.092 3
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0014070 Not Cancer Driver No 46 0.094 145 14 0.097 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0014070 Not Cancer Driver No 37 0.132 226 32 0.142 0
HLCS HLCS P50747 Biotin--protein ligase chr21 GO:0014070 Not Cancer Driver No 95 0.131 158 15 0.095 23
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0014070 Not Cancer Driver No 92 0.181 29 4 0.138 19
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0014070 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0014070 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 GO:0014070 Not Cancer Driver No 35 0.085 339 25 0.074 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0014070 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0014070 Census Yes 37 0.095 171 22 0.129 4
HOXB13 HOXB13 Q92826 Homeobox protein Hox-B13 chr17 GO:0014070 Not Cancer Driver No 61 0.215 179 37 0.207 1
HOXD13 HOXD13 P35453 Homeobox protein Hox-D13 chr2 GO:0014070 Census, Compendium Yes 43 0.125 113 12 0.106 9
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0014070 Not Cancer Driver No 24 0.124 42 4 0.095 3
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0014070 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0014070 Not Cancer Driver No 27 0.067 30 0 0.0 14
HSD3B1 HSD3B1 P14060 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 chr1 GO:0014070 Not Cancer Driver No 69 0.185 25 3 0.12 0
HSD3B2_ENST00000369416 HSD3B2 P26439 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 chr1 GO:0014070 Not Cancer Driver No 83 0.223 24 9 0.375 28
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0014070 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0014070 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0014070 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0014070 Not Cancer Driver No 73 0.112 282 35 0.124 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0014070 Not Cancer Driver No 91 0.233 33 15 0.455 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0014070 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0014070 Census, Compendium Yes 14 0.118 34 4 0.118 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0014070 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0014070 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFIT1B IFIT1B Q5T764 Interferon-induced protein with tetratricopeptide repeats 1B chr10 GO:0014070 Not Cancer Driver No 59 0.124 21 1 0.048 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0014070 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0014070 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0014070 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0014070 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0014070 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0014070 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0014070 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0014070 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0014070 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0014070 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0014070 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0014070 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0014070 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0014070 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0014070 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0014070 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0014070 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0014070 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0014070 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGFBP7 IGFBP7 Q16270 Insulin-like growth factor-binding protein 7 chr4 GO:0014070 Not Cancer Driver No 22 0.078 100 12 0.12 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0014070 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0014070 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0014070 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0014070 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0014070 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL22_ENST00000328087 IL22 Q9GZX6 Interleukin-22 chr12 GO:0014070 Not Cancer Driver No 32 0.179 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0014070 Not Cancer Driver No 35 0.165 58 7 0.121 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0014070 Not Cancer Driver No 49 0.153 84 12 0.143 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0014070 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0014070 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0014070 Not Cancer Driver No 42 0.094 34 2 0.059 7
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0014070 Not Cancer Driver No 37 0.134 43 1 0.023 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0014070 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0014070 Not Cancer Driver No 36 0.084 204 21 0.103 1
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0014070 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0014070 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 GO:0014070 Not Cancer Driver No 359 0.133 394 57 0.145 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0014070 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUND JUND P17535 Transcription factor JunD chr19 GO:0014070 Not Cancer Driver No 21 0.061 313 19 0.061 0
JUP JUP P14923 Junction plakoglobin chr17 GO:0014070 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0014070 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0014070 Not Cancer Driver No 65 0.127 173 21 0.121 3
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0014070 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0014070 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0014070 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0014070 Not Cancer Driver No 99 0.233 68 22 0.324 1
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0014070 Not Cancer Driver No 49 0.257 0 0 0.0 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0014070 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0014070 Not Cancer Driver No 67 0.079 291 28 0.096 3
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0014070 Not Cancer Driver No 114 0.127 405 60 0.148 0
KL KL Q9UEF7 Klotho chr13 GO:0014070 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0014070 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0014070 Not Cancer Driver No 34 0.139 154 24 0.156 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0014070 Not Cancer Driver No 103 0.222 20 5 0.25 1
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0014070 Not Cancer Driver No 43 0.098 28 2 0.071 34
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0014070 Not Cancer Driver No 54 0.125 388 46 0.119 0
LEP LEP P41159 Leptin chr7 GO:0014070 Not Cancer Driver No 29 0.174 0 0 0.0 2
LONP2 LONP2 Q86WA8 Lon protease homolog 2, peroxisomal chr16 GO:0014070 Not Cancer Driver No 116 0.136 163 26 0.16 0
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0014070 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0014070 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0014070 Not Cancer Driver No 519 0.205 90 17 0.189 23
LY6D LY6D Q14210 Lymphocyte antigen 6D chr8 GO:0014070 Not Cancer Driver No 23 0.18 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0014070 Census Yes 95 0.186 84 12 0.143 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0014070 Not Cancer Driver No 75 0.144 44 6 0.136 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 GO:0014070 Not Cancer Driver No 22 0.182 24 1 0.042 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0014070 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0014070 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0014070 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0014070 Not Cancer Driver No 52 0.171 304 52 0.171 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0014070 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0014070 Not Cancer Driver No 92 0.195 408 81 0.199 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0014070 Not Cancer Driver No 54 0.205 47 13 0.277 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 GO:0014070 Not Cancer Driver No 53 0.141 35 7 0.2 15
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0014070 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP19 MMP19 Q99542 Matrix metalloproteinase-19 chr12 GO:0014070 Not Cancer Driver No 94 0.185 98 20 0.204 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0014070 Not Cancer Driver No 123 0.186 29 6 0.207 2
MRGPRX1 MRGPRX1 Q96LB2 Mas-related G-protein coupled receptor member X1 chr11 GO:0014070 Not Cancer Driver No 123 0.382 0 0 0.0 0
MSN MSN P26038 Moesin chrX GO:0014070 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0014070 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0014070 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 GO:0014070 Not Cancer Driver No 37 0.131 15 0 0.0 0
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 GO:0014070 Not Cancer Driver No 95 0.145 125 22 0.176 53
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0014070 Not Cancer Driver No 1 0.042 0 0 0.0 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0014070 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0014070 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0014070 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0014070 Not Cancer Driver No 36 0.161 132 20 0.152 0
NASP NASP P49321 Nuclear autoantigenic sperm protein chr1 GO:0014070 Not Cancer Driver No 95 0.121 615 81 0.132 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0014070 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0014070 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 GO:0014070 Not Cancer Driver No 26 0.149 92 17 0.185 1
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0014070 Not Cancer Driver No 92 0.169 285 39 0.137 12
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0014070 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0014070 Compendium Yes 37 0.117 102 9 0.088 1
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0014070 Not Cancer Driver No 84 0.308 206 65 0.316 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0014070 Not Cancer Driver No 35 0.15 171 16 0.094 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0014070 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0014070 Census, Compendium Yes 363 0.142 686 87 0.127 3
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0014070 Not Cancer Driver No 229 0.286 429 114 0.266 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0014070 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR0B2 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0014070 Not Cancer Driver No 35 0.136 10 2 0.2 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0014070 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0014070 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0014070 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0014070 Census Yes 83 0.133 298 37 0.124 0
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 GO:0014070 Not Cancer Driver No 141 0.122 998 124 0.124 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0014070 Census, Compendium Yes 249 0.297 57 21 0.368 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0014070 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0014070 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0014070 Not Cancer Driver No 107 0.268 58 27 0.466 0
OSBPL7_ENST00000392507 OSBPL7 Q9BZF2 Oxysterol-binding protein-related protein 7 chr17 GO:0014070 Not Cancer Driver No 99 0.118 395 44 0.111 0
OTC OTC P00480 Ornithine transcarbamylase, mitochondrial chrX GO:0014070 Not Cancer Driver No 89 0.251 24 4 0.167 111
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0014070 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0014070 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0014070 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0014070 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0014070 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0014070 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0014070 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX6 P2RX6 O15547 P2X purinoceptor 6 chr22 GO:0014070 Not Cancer Driver No 33 0.075 43 1 0.023 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0014070 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0014070 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY11 P2RY11 Q96G91 P2Y purinoceptor 11 chr19 GO:0014070 Not Cancer Driver No 47 0.126 31 1 0.032 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0014070 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 GO:0014070 Not Cancer Driver No 67 0.178 60 13 0.217 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0014070 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0014070 Not Cancer Driver No 50 0.152 10 5 0.5 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0014070 Not Cancer Driver No 129 0.133 254 37 0.146 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0014070 Not Cancer Driver No 54 0.127 45 7 0.156 2
PAPPA PAPPA Q13219 Pappalysin-1 chr9 GO:0014070 Not Cancer Driver No 370 0.227 239 37 0.155 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0014070 Not Cancer Driver No 119 0.117 320 34 0.106 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0014070 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0014070 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0014070 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0014070 Not Cancer Driver No 139 0.185 336 61 0.182 2
PDCD7 PDCD7 Q8N8D1 Programmed cell death protein 7 chr15 GO:0014070 Not Cancer Driver No 47 0.097 275 15 0.055 0
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0014070 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0014070 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0014070 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0014070 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0014070 Census Yes 37 0.154 99 22 0.222 2
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0014070 Not Cancer Driver No 32 0.113 238 23 0.097 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0014070 Not Cancer Driver No 14 0.047 38 4 0.105 0
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0014070 Not Cancer Driver No 12 0.092 35 5 0.143 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0014070 Not Cancer Driver No 47 0.112 167 17 0.102 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0014070 Not Cancer Driver No 109 0.408 142 62 0.437 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0014070 Census Yes 160 0.124 948 116 0.122 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0014070 Not Cancer Driver No 81 0.172 48 11 0.229 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0014070 Not Cancer Driver No 144 0.192 56 7 0.125 30
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0014070 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0014070 Not Cancer Driver No 318 0.289 121 39 0.322 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0014070 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0014070 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0014070 Not Cancer Driver No 112 0.195 26 5 0.192 101
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0014070 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0014070 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLIN2 PLIN2 Q99541 Perilipin-2 chr9 GO:0014070 Not Cancer Driver No 43 0.098 126 14 0.111 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0014070 Not Cancer Driver No 2 0.037 23 1 0.043 0
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 GO:0014070 Not Cancer Driver No 38 0.198 3 0 0.0 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0014070 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0014070 Not Cancer Driver No 86 0.11 115 10 0.087 2
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0014070 Not Cancer Driver No 62 0.092 93 4 0.043 9
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0014070 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0014070 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0014070 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0014070 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0014070 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 GO:0014070 Not Cancer Driver No 60 0.134 68 10 0.147 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 GO:0014070 Not Cancer Driver No 70 0.14 73 12 0.164 0
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0014070 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0014070 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0014070 Census Yes 53 0.151 24 0 0.0 2
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0014070 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0014070 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0014070 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0014070 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSMB2 PSMB2 P49721 Proteasome subunit beta type-2 chr1 GO:0014070 Not Cancer Driver No 24 0.119 0 0 0.0 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 GO:0014070 Not Cancer Driver No 44 0.196 21 6 0.286 3
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0014070 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0014070 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0014070 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0014070 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0014070 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0014070 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0014070 Not Cancer Driver No 248 0.172 325 64 0.197 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0014070 Not Cancer Driver No 42 0.124 47 5 0.106 3
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0014070 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0014070 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0014070 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0014070 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0014070 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0014070 Not Cancer Driver No 158 0.147 589 87 0.148 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0014070 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0014070 Not Cancer Driver No 97 0.105 197 19 0.096 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0014070 Not Cancer Driver No 132 0.133 495 71 0.143 0
REN REN P00797 Renin chr1 GO:0014070 Not Cancer Driver No 60 0.148 10 0 0.0 3
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0014070 Not Cancer Driver No 142 0.129 868 113 0.13 4
RFTN1 RFTN1 Q14699 Raftlin chr3 GO:0014070 Not Cancer Driver No 87 0.151 319 44 0.138 0
RFTN2 RFTN2 Q52LD8 Raftlin-2 chr2 GO:0014070 Not Cancer Driver No 76 0.152 232 48 0.207 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0014070 Not Cancer Driver No 68 0.332 5 4 0.8 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0014070 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0014070 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0014070 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNLS RNLS Q5VYX0 Renalase chr10 GO:0014070 Not Cancer Driver No 42 0.123 15 1 0.067 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0014070 Not Cancer Driver No 145 0.104 732 81 0.111 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0014070 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0014070 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 GO:0014070 Not Cancer Driver No 21 0.154 13 3 0.231 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0014070 Not Cancer Driver No 45 0.086 226 26 0.115 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0014070 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:0014070 Not Cancer Driver No 28 0.115 168 19 0.113 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0014070 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0014070 Not Cancer Driver No 1703 0.343 782 281 0.359 51
RYR3 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0014070 Not Cancer Driver No 1079 0.222 649 162 0.25 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0014070 Not Cancer Driver No 12 0.132 14 2 0.143 0
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0014070 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0014070 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0014070 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0014070 Not Cancer Driver No 129 0.199 57 11 0.193 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0014070 Not Cancer Driver No 31 0.1 259 30 0.116 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0014070 Not Cancer Driver No 51 0.122 57 5 0.088 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0014070 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0014070 Census, Compendium Yes 58 0.135 86 16 0.186 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0014070 Compendium Yes 172 0.135 617 73 0.118 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0014070 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0014070 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC10A1 SLC10A1 Q14973 Sodium/bile acid cotransporter chr14 GO:0014070 Not Cancer Driver No 39 0.112 0 0 0.0 4
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0014070 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0014070 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0014070 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC22A6 SLC22A6 Q4U2R8 Solute carrier family 22 member 6 chr11 GO:0014070 Not Cancer Driver No 85 0.151 72 11 0.153 0
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0014070 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0014070 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0014070 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0014070 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 GO:0014070 Not Cancer Driver No 62 0.098 171 12 0.07 0
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0014070 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC6A1_ENST00000643498 SLC6A1 P30531 Sodium- and chloride-dependent GABA transporter 1 chr3 GO:0014070 Not Cancer Driver No 119 0.199 24 9 0.375 4
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0014070 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0014070 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0014070 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0014070 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0014070 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0014070 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLIT3_ENST00000519560 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0014070 Not Cancer Driver No 351 0.23 40 9 0.225 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0014070 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0014070 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0014070 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0014070 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0014070 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0014070 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0014070 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0014070 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX30 SOX30 O94993 Transcription factor SOX-30 chr5 GO:0014070 Not Cancer Driver No 103 0.137 659 89 0.135 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0014070 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0014070 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0014070 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0014070 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0014070 Not Cancer Driver No 48 0.189 0 0 0.0 21
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0014070 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRR SRR Q9GZT4 Serine racemase chr17 GO:0014070 Not Cancer Driver No 40 0.118 32 6 0.188 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 GO:0014070 Census, Compendium Yes 38 0.172 219 38 0.174 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0014070 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0014070 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0014070 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0014070 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0014070 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0014070 Not Cancer Driver No 60 0.165 45 12 0.267 0
ST8SIA2 ST8SIA2 Q92186 Alpha-2,8-sialyltransferase 8B chr15 GO:0014070 Not Cancer Driver No 84 0.224 38 8 0.211 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0014070 Not Cancer Driver No 131 0.175 144 25 0.174 26
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0014070 Not Cancer Driver No 59 0.239 58 12 0.207 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0014070 Not Cancer Driver No 71 0.235 112 29 0.259 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0014070 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 GO:0014070 Not Cancer Driver No 137 0.295 31 17 0.548 5
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0014070 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0014070 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAT TAT P17735 Tyrosine aminotransferase chr16 GO:0014070 Not Cancer Driver No 102 0.225 75 21 0.28 1
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0014070 Not Cancer Driver No 47 0.137 17 4 0.235 1
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0014070 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0014070 Compendium Yes 61 0.18 285 52 0.182 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0014070 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0014070 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0014070 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0014070 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0014070 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0014070 Not Cancer Driver No 123 0.179 107 26 0.243 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0014070 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBD THBD P07204 Thrombomodulin chr20 GO:0014070 Not Cancer Driver No 39 0.068 51 3 0.059 9
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0014070 Not Cancer Driver No 188 0.161 320 58 0.181 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0014070 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0014070 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0014070 Not Cancer Driver No 123 0.136 0 0 0.0 1
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0014070 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0014070 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0014070 Not Cancer Driver No 47 0.162 37 7 0.189 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0014070 Not Cancer Driver No 24 0.103 45 3 0.067 0
TOMM20 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 GO:0014070 Not Cancer Driver No 8 0.055 25 1 0.04 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0014070 Not Cancer Driver No 59 0.097 140 8 0.057 0
TP53I13 TP53I13 Q8NBR0 Tumor protein p53-inducible protein 13 chr17 GO:0014070 Not Cancer Driver No 38 0.097 231 25 0.108 0
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0014070 Not Cancer Driver No 118 0.241 55 17 0.309 1
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0014070 Not Cancer Driver No 226 0.188 957 167 0.175 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0014070 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 GO:0014070 Not Cancer Driver No 47 0.133 71 13 0.183 0
TRPA1 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0014070 Not Cancer Driver No 324 0.29 62 14 0.226 1
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0014070 Not Cancer Driver No 200 0.239 23 2 0.087 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0014070 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0014070 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0014070 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0014070 Not Cancer Driver No 5 0.03 1 0 0.0 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 GO:0014070 Not Cancer Driver No 22 0.133 34 4 0.118 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0014070 Not Cancer Driver No 61 0.156 77 14 0.182 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0014070 Not Cancer Driver No 22 0.07 41 0 0.0 0
TYR TYR P14679 Tyrosinase chr11 GO:0014070 Not Cancer Driver No 156 0.295 52 15 0.288 111
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0014070 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0014070 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCN UCN P55089 Urocortin chr2 GO:0014070 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0014070 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0014070 Not Cancer Driver No 43 0.14 1 0 0.0 0
UCP3 UCP3 P55916 Mitochondrial uncoupling protein 3 chr11 GO:0014070 Not Cancer Driver No 37 0.119 7 1 0.143 1
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0014070 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT3A2 UGT3A2 Q3SY77 UDP-glucuronosyltransferase 3A2 chr5 GO:0014070 Not Cancer Driver No 169 0.323 0 0 0.0 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0014070 Census, Compendium Yes 122 0.109 602 69 0.115 0
VGF VGF O15240 Neurosecretory protein VGF chr7 GO:0014070 Not Cancer Driver No 48 0.078 593 47 0.079 0
VKORC1 VKORC1 Q9BQB6 Vitamin K epoxide reductase complex subunit 1 chr16 GO:0014070 Not Cancer Driver No 14 0.086 3 0 0.0 19
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0014070 Not Cancer Driver No 26 0.1 102 6 0.059 1
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0014070 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0014070 Not Cancer Driver No 55 0.158 11 1 0.091 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0014070 Not Cancer Driver No 213 0.125 577 65 0.113 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0014070 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0014070 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0014070 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0014070 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0014070 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0014070 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0014070 Not Cancer Driver No 26 0.044 415 14 0.034 0