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Total number of protein in "GO:0009889" GO term:  1061

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0009889 Not Cancer Driver No 97 0.1 140 14 0.1 5
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0009889 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0009889 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0009889 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCB7_ENST00000373394 ABCB7 O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial chrX GO:0009889 Not Cancer Driver No 117 0.156 79 14 0.177 4
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0009889 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0009889 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0009889 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABCG4 ABCG4 Q9H172 ATP-binding cassette sub-family G member 4 chr11 GO:0009889 Not Cancer Driver No 122 0.189 29 7 0.241 0
ABHD6 ABHD6 Q9BV23 Monoacylglycerol lipase ABHD6 chr3 GO:0009889 Not Cancer Driver No 38 0.113 11 2 0.182 0
ACADL ACADL P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial chr2 GO:0009889 Not Cancer Driver No 63 0.147 51 3 0.059 0
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 GO:0009889 Not Cancer Driver No 61 0.145 41 5 0.122 19
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 GO:0009889 Not Cancer Driver No 50 0.076 100 5 0.05 37
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0009889 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0009889 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACMSD ACMSD Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase chr2 GO:0009889 Not Cancer Driver No 65 0.193 9 2 0.222 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 GO:0009889 Not Cancer Driver No 43 0.135 52 7 0.135 0
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0009889 Not Cancer Driver No 51 0.157 31 6 0.194 8
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0009889 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0009889 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0009889 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0009889 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0009889 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0009889 Compendium Yes 213 0.134 485 47 0.097 0
ADGRF1 ADGRF1 Q5T601 Adhesion G-protein coupled receptor F1 chr6 GO:0009889 Not Cancer Driver No 159 0.175 8 0 0.0 0
ADGRF5_ENST00000265417 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0009889 Not Cancer Driver No 255 0.189 53 11 0.208 0
ADGRG3 ADGRG3 Q86Y34 Adhesion G protein-coupled receptor G3 chr16 GO:0009889 Not Cancer Driver No 87 0.158 42 5 0.119 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0009889 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0009889 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0009889 Not Cancer Driver No 23 0.069 0 0 0.0 0
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 GO:0009889 Not Cancer Driver No 126 0.147 87 11 0.126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0009889 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:0009889 Not Cancer Driver No 110 0.128 143 19 0.133 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:0009889 Not Cancer Driver No 100 0.116 183 24 0.131 0
AGT AGT P01019 Angiotensinogen chr1 GO:0009889 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0009889 Not Cancer Driver No 98 0.27 0 0 0.0 0
AGXT2 AGXT2 Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial chr5 GO:0009889 Not Cancer Driver No 136 0.265 11 5 0.455 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0009889 Not Cancer Driver No 56 0.283 0 0 0.0 8
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0009889 Not Cancer Driver No 14 0.095 61 6 0.098 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 GO:0009889 Not Cancer Driver No 26 0.117 24 3 0.125 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0009889 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0009889 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0009889 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0009889 Census Yes 77 0.16 84 9 0.107 2
ALDH2 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 GO:0009889 Census Yes 60 0.116 44 1 0.023 0
ALG10B ALG10B Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 GO:0009889 Not Cancer Driver No 90 0.19 0 0 0.0 0
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0009889 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0009889 Not Cancer Driver No 129 0.191 16 2 0.125 0
AMELX_ENST00000380714 AMELX Q99217 Amelogenin, X isoform chrX GO:0009889 Not Cancer Driver No 40 0.209 127 28 0.22 3
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0009889 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0009889 Not Cancer Driver No 34 0.094 192 18 0.094 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0009889 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 GO:0009889 Not Cancer Driver No 95 0.097 188 12 0.064 0
APLN APLN Q9ULZ1 Apelin chrX GO:0009889 Not Cancer Driver No 8 0.104 51 6 0.118 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0009889 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0009889 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0009889 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0009889 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0009889 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0009889 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0009889 Not Cancer Driver No 14 0.141 12 2 0.167 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0009889 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOPT1 COA8 Q96IL0 Cytochrome c oxidase assembly factor 8 chr14 GO:0009889 Not Cancer Driver No 23 0.112 48 4 0.083 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0009889 Not Cancer Driver No 67 0.094 292 31 0.106 1
AR AR P10275 Androgen receptor chrX GO:0009889 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0009889 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0009889 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0009889 Not Cancer Driver No 135 0.144 267 41 0.154 17
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0009889 Census Yes 77 0.098 511 56 0.11 0
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0009889 Not Cancer Driver No 17 0.152 112 17 0.152 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0009889 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASAH1_ENST00000262097 ASAH1 Q13510 Acid ceramidase chr8 GO:0009889 Not Cancer Driver No 47 0.119 10 3 0.3 14
ASIP_ENST00000374954 ASIP P42127 Agouti-signaling protein chr20 GO:0009889 Not Cancer Driver No 16 0.121 36 9 0.25 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0009889 Not Cancer Driver No 65 0.158 63 8 0.127 86
ASXL3 ASXL3 Q9C0F0 Putative Polycomb group protein ASXL3 chr18 GO:0009889 Not Cancer Driver No 568 0.253 1879 477 0.254 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0009889 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0009889 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0009889 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0009889 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0009889 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0009889 Compendium Yes 160 0.126 1136 139 0.122 0
ATG101 ATG101 Q9BSB4 Autophagy-related protein 101 chr12 GO:0009889 Not Cancer Driver No 21 0.096 5 0 0.0 0
ATG13_ENST00000359513 ATG13 O75143 Autophagy-related protein 13 chr11 GO:0009889 Not Cancer Driver No 55 0.106 205 27 0.132 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0009889 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0009889 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0009889 Census Yes 115 0.112 115 16 0.139 6
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0009889 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0009889 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0009889 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0009889 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVIL AVIL O75366 Advillin chr12 GO:0009889 Not Cancer Driver No 91 0.111 138 17 0.123 2
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0009889 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0009889 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0009889 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0009889 Census, Compendium Yes 120 0.139 619 88 0.142 4
AZU1 AZU1 P20160 Azurocidin chr19 GO:0009889 Not Cancer Driver No 42 0.167 53 13 0.245 0
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 GO:0009889 Not Cancer Driver No 61 0.118 23 2 0.087 0
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 GO:0009889 Not Cancer Driver No 105 0.143 328 39 0.119 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0009889 Not Cancer Driver No 57 0.099 571 57 0.1 7
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0009889 Not Cancer Driver No 150 0.191 394 73 0.185 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0009889 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0009889 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0009889 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0009889 Census, Compendium Yes 421 0.458 899 408 0.454 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0009889 Not Cancer Driver No 21 0.044 213 10 0.047 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0009889 Census Yes 153 0.108 667 70 0.105 8
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0009889 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0009889 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0009889 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0009889 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0009889 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0009889 Compendium Yes 141 0.136 601 70 0.116 19
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0009889 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0009889 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0009889 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:0009889 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:0009889 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0009889 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 GO:0009889 Not Cancer Driver No 40 0.095 138 13 0.094 0
BUD31 BUD31 P41223 Protein BUD31 homolog chr7 GO:0009889 Not Cancer Driver No 20 0.139 32 4 0.125 0
C19orf66 SHFL Q9NUL5 Shiftless antiviral inhibitor of ribosomal frameshifting protein chr19 GO:0009889 Not Cancer Driver No 23 0.079 166 12 0.072 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0009889 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0009889 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0009889 Not Cancer Driver No 42 0.171 73 14 0.192 0
C3 C3 P01024 Complement C3 chr19 GO:0009889 Not Cancer Driver No 337 0.203 287 50 0.174 12
C6orf203_ENST00000405204 MTRES1 Q9P0P8 Mitochondrial transcription rescue factor 1 chr6 GO:0009889 Not Cancer Driver No 28 0.117 45 4 0.089 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0009889 Not Cancer Driver No 90 0.234 42 14 0.333 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0009889 Not Cancer Driver No 81 0.116 46 11 0.239 0
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:0009889 Not Cancer Driver No 93 0.128 503 63 0.125 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0009889 Not Cancer Driver No 30 0.169 2 0 0.0 0
CC2D1A CC2D1A Q6P1N0 Coiled-coil and C2 domain-containing protein 1A chr19 GO:0009889 Not Cancer Driver No 146 0.154 718 100 0.139 0
CCDC22 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX GO:0009889 Not Cancer Driver No 62 0.099 243 18 0.074 2
CCDC3 CCDC3 Q9BQI4 Coiled-coil domain-containing protein 3 chr10 GO:0009889 Not Cancer Driver No 40 0.148 68 18 0.265 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0009889 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0009889 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0009889 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0009889 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0009889 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN6_ENST00000230529 CCN6 O95389 Cellular communication network factor 6 chr6 GO:0009889 Not Cancer Driver No 39 0.11 11 0 0.0 9
CCNK CCNK O75909 Cyclin-K chr14 GO:0009889 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0009889 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0009889 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0009889 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0009889 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0009889 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0009889 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0009889 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0009889 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0009889 Not Cancer Driver No 41 0.075 36 2 0.056 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0009889 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0009889 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0009889 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0009889 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0009889 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0009889 Census Yes 31 0.105 185 20 0.108 0
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:0009889 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0009889 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDK14 CDK14 O94921 Cyclin-dependent kinase 14 chr7 GO:0009889 Not Cancer Driver No 93 0.198 154 21 0.136 0
CDK15 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 GO:0009889 Not Cancer Driver No 66 0.152 35 4 0.114 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:0009889 Not Cancer Driver No 55 0.111 139 30 0.216 0
CDK17 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 GO:0009889 Not Cancer Driver No 76 0.145 198 26 0.131 0
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 GO:0009889 Not Cancer Driver No 64 0.135 132 17 0.129 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0009889 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0009889 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0009889 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0009889 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0009889 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0009889 Not Cancer Driver No 60 0.11 377 35 0.093 5
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0009889 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0009889 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0009889 Not Cancer Driver No 3 0.009 276 2 0.007 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:0009889 Not Cancer Driver No 56 0.115 166 17 0.102 0
CER1 CER1 O95813 Cerberus chr9 GO:0009889 Not Cancer Driver No 70 0.262 119 27 0.227 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0009889 Not Cancer Driver No 29 0.083 19 0 0.0 1
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0009889 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0009889 Not Cancer Driver No 40 0.083 44 2 0.045 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0009889 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0009889 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0009889 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0009889 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0009889 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0009889 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0009889 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0009889 Not Cancer Driver No 13 0.107 7 0 0.0 0
CIITA_ENST00000324288 CIITA P33076 MHC class II transactivator chr16 GO:0009889 Census, Compendium Yes 195 0.173 318 53 0.167 2
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0009889 Not Cancer Driver No 23 0.085 230 18 0.078 0
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 GO:0009889 Not Cancer Driver No 93 0.104 708 83 0.117 0
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 GO:0009889 Not Cancer Driver No 124 0.138 224 38 0.17 8
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0009889 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0009889 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 GO:0009889 Not Cancer Driver No 104 0.208 151 37 0.245 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0009889 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 GO:0009889 Census, Compendium Yes 190 0.113 71 6 0.085 1
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0009889 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0009889 Census Yes 11 0.062 19 0 0.0 0
CNEP1R1_ENST00000427478 CNEP1R1 Q8N9A8 Nuclear envelope phosphatase-regulatory subunit 1 chr16 GO:0009889 Not Cancer Driver No 8 0.064 0 0 0.0 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0009889 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0009889 Not Cancer Driver No 31 0.109 21 1 0.048 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 GO:0009889 Not Cancer Driver No 4 0.038 57 3 0.053 0
COQ3 COQ3 Q9NZJ6 Ubiquinone biosynthesis O-methyltransferase, mitochondrial chr6 GO:0009889 Not Cancer Driver No 47 0.127 22 5 0.227 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0009889 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB2_ENST00000507071 CPEB2 Q7Z5Q1 Cytoplasmic polyadenylation element-binding protein 2 chr4 GO:0009889 Not Cancer Driver No 66 0.112 269 17 0.063 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0009889 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0009889 Not Cancer Driver No 85 0.117 443 54 0.122 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0009889 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0009889 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0009889 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0009889 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0009889 Not Cancer Driver No 15 0.125 78 5 0.064 0
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0009889 Census, Compendium Yes 63 0.099 606 62 0.102 0
CRTC2 CRTC2 Q53ET0 CREB-regulated transcription coactivator 2 chr1 GO:0009889 Not Cancer Driver No 92 0.133 674 88 0.131 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 GO:0009889 Census Yes 70 0.113 608 68 0.112 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0009889 Not Cancer Driver No 76 0.13 91 5 0.055 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0009889 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0009889 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 GO:0009889 Not Cancer Driver No 20 0.082 0 0 0.0 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 GO:0009889 Not Cancer Driver No 121 0.126 624 87 0.139 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0009889 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0009889 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0009889 Not Cancer Driver No 34 0.093 0 0 0.0 31
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0009889 Not Cancer Driver No 80 0.225 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0009889 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0009889 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYGB CYGB Q8WWM9 Cytoglobin chr17 GO:0009889 Not Cancer Driver No 32 0.168 47 5 0.106 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0009889 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0009889 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0009889 Not Cancer Driver No 109 0.216 48 8 0.167 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0009889 Not Cancer Driver No 144 0.187 680 125 0.184 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0009889 Not Cancer Driver No 157 0.207 641 134 0.209 0
DAND5 DAND5 Q8N907 DAN domain family member 5 chr19 GO:0009889 Not Cancer Driver No 32 0.169 26 3 0.115 0
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 GO:0009889 Not Cancer Driver No 75 0.111 333 26 0.078 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:0009889 Not Cancer Driver No 68 0.111 311 22 0.071 0
DBI_ENST00000355857 DBI P07108 Acyl-CoA-binding protein chr2 GO:0009889 Not Cancer Driver No 13 0.149 27 6 0.222 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0009889 Not Cancer Driver No 57 0.136 167 24 0.144 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0009889 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0009889 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0009889 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0009889 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0009889 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX20 DDX20 Q9UHI6 Probable ATP-dependent RNA helicase DDX20 chr1 GO:0009889 Not Cancer Driver No 89 0.108 299 33 0.11 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0009889 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0009889 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0009889 Census Yes 74 0.121 225 23 0.102 0
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 GO:0009889 Census, Compendium Yes 44 0.091 129 7 0.054 5
DEDD_ENST00000545495 DEDD O75618 Death effector domain-containing protein chr1 GO:0009889 Not Cancer Driver No 36 0.113 90 7 0.078 0
DEK DEK P35659 Protein DEK chr6 GO:0009889 Census Yes 47 0.125 297 41 0.138 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0009889 Not Cancer Driver No 56 0.144 17 2 0.118 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0009889 Not Cancer Driver No 56 0.059 264 11 0.042 0
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 GO:0009889 Not Cancer Driver No 85 0.179 7 1 0.143 53
DHH DHH O43323 Desert hedgehog protein chr12 GO:0009889 Not Cancer Driver No 36 0.091 57 7 0.123 1
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0009889 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0009889 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0009889 Compendium Yes 182 0.143 331 42 0.127 0
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:0009889 Not Cancer Driver No 73 0.267 44 4 0.091 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0009889 Not Cancer Driver No 114 0.129 264 22 0.083 1
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0009889 Not Cancer Driver No 62 0.121 145 29 0.2 24
DKK3_ENST00000326932 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 GO:0009889 Not Cancer Driver No 44 0.126 161 22 0.137 0
DKKL1 DKKL1 Q9UK85 Dickkopf-like protein 1 chr19 GO:0009889 Not Cancer Driver No 44 0.182 136 31 0.228 0
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0009889 Not Cancer Driver No 71 0.246 223 57 0.256 1
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:0009889 Census, Compendium Yes 35 0.103 196 26 0.133 0
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 GO:0009889 Not Cancer Driver No 67 0.108 425 48 0.113 0
DNAJC24 DNAJC24 Q6P3W2 DnaJ homolog subfamily C member 24 chr11 GO:0009889 Not Cancer Driver No 18 0.121 11 0 0.0 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0009889 Not Cancer Driver No 60 0.119 131 17 0.13 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 GO:0009889 Not Cancer Driver No 25 0.111 83 7 0.084 3
DND1 DND1 Q8IYX4 Dead end protein homolog 1 chr5 GO:0009889 Not Cancer Driver No 23 0.065 36 0 0.0 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0009889 Census Yes 138 0.159 270 43 0.159 22
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 GO:0009889 Not Cancer Driver No 50 0.088 217 13 0.06 6
DPH1 DPH1 Q9BZG8 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 chr17 GO:0009889 Not Cancer Driver No 41 0.093 67 8 0.119 2
DPH2 DPH2 Q9BQC3 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 chr1 GO:0009889 Not Cancer Driver No 77 0.157 177 26 0.147 0
DPH3 DPH3 Q96FX2 DPH3 homolog chr3 GO:0009889 Not Cancer Driver No 12 0.146 0 0 0.0 0
DPH5 DPH5 Q9H2P9 Diphthine methyl ester synthase chr1 GO:0009889 Not Cancer Driver No 25 0.088 18 1 0.056 0
DPH6 DPH6 Q7L8W6 Diphthine--ammonia ligase chr15 GO:0009889 Not Cancer Driver No 29 0.109 0 0 0.0 0
DPH7 DPH7 Q9BTV6 Diphthine methyltransferase chr9 GO:0009889 Not Cancer Driver No 38 0.084 107 10 0.093 0
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0009889 Not Cancer Driver No 28 0.071 41 4 0.098 0
DUOXA1_ENST00000560572 DUOXA1 Q1HG43 Dual oxidase maturation factor 1 chr15 GO:0009889 Not Cancer Driver No 40 0.117 38 7 0.184 0
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 GO:0009889 Not Cancer Driver No 40 0.125 0 0 0.0 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0009889 Not Cancer Driver No 77 0.128 294 39 0.133 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0009889 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 GO:0009889 Not Cancer Driver No 44 0.107 242 32 0.132 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 GO:0009889 Not Cancer Driver No 20 0.071 105 10 0.095 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0009889 Not Cancer Driver No 122 0.134 554 70 0.126 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:0009889 Not Cancer Driver No 132 0.152 582 85 0.146 0
EAPP EAPP Q56P03 E2F-associated phosphoprotein chr14 GO:0009889 Not Cancer Driver No 35 0.123 210 27 0.129 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0009889 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEFSEC EEFSEC P57772 Selenocysteine-specific elongation factor chr3 GO:0009889 Not Cancer Driver No 80 0.134 124 21 0.169 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0009889 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0009889 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0009889 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0009889 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0009889 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0009889 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0009889 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX GO:0009889 Not Cancer Driver No 52 0.11 51 7 0.137 1
EIF2S3B EIF2S3B Q2VIR3 Eukaryotic translation initiation factor 2 subunit 3B chr12 GO:0009889 Not Cancer Driver No 16 0.034 53 2 0.038 0
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 GO:0009889 Census, Compendium Yes 73 0.164 27 1 0.037 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:0009889 Census Yes 77 0.189 27 14 0.519 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0009889 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4E2 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 GO:0009889 Not Cancer Driver No 27 0.11 80 5 0.062 0
EIF4EBP1 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 GO:0009889 Not Cancer Driver No 8 0.068 118 8 0.068 0
EIF4EBP2 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 GO:0009889 Not Cancer Driver No 17 0.142 118 14 0.119 0
EIF4EBP3 EIF4EBP3 O60516 Eukaryotic translation initiation factor 4E-binding protein 3 chr5 GO:0009889 Not Cancer Driver No 9 0.09 78 6 0.077 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0009889 Not Cancer Driver No 116 0.118 899 101 0.112 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0009889 Not Cancer Driver No 26 0.12 54 6 0.111 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0009889 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:0009889 Not Cancer Driver No 20 0.131 28 4 0.143 0
EIF5AL1 EIF5AL1 Q6IS14 Eukaryotic translation initiation factor 5A-1-like chr10 GO:0009889 Not Cancer Driver No 21 0.136 16 4 0.25 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0009889 Not Cancer Driver No 37 0.24 21 5 0.238 5
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 GO:0009889 Not Cancer Driver No 30 0.122 17 3 0.176 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0009889 Not Cancer Driver No 118 0.306 117 34 0.291 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0009889 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0009889 Not Cancer Driver No 34 0.114 25 4 0.16 2
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0009889 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0009889 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENG ENG P17813 Endoglin chr9 GO:0009889 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0009889 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0009889 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0009889 Not Cancer Driver No 102 0.223 65 19 0.292 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0009889 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0009889 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:0009889 Not Cancer Driver No 341 0.329 83 39 0.47 0
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:0009889 Not Cancer Driver No 61 0.1 22 1 0.045 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0009889 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0009889 Census Yes 120 0.131 225 27 0.12 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0009889 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERFE ERFE Q4G0M1 Erythroferrone chr2 GO:0009889 Not Cancer Driver No 4 0.011 179 0 0.0 0
ERLIN1 ERLIN1 O75477 Erlin-1 chr10 GO:0009889 Not Cancer Driver No 29 0.083 46 4 0.087 1
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 GO:0009889 Not Cancer Driver No 38 0.112 22 3 0.136 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0009889 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0009889 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETF1 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 GO:0009889 Not Cancer Driver No 60 0.137 28 11 0.393 0
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0009889 Not Cancer Driver No 68 0.154 78 9 0.115 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0009889 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0009889 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0009889 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0009889 Not Cancer Driver No 58 0.132 154 18 0.117 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0009889 Census, Compendium Yes 120 0.161 284 44 0.155 11
F2 F2 P00734 Prothrombin chr11 GO:0009889 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0009889 Not Cancer Driver No 73 0.172 19 2 0.105 0
FABP3 FABP3 P05413 Fatty acid-binding protein, heart chr1 GO:0009889 Not Cancer Driver No 22 0.165 3 0 0.0 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0009889 Not Cancer Driver No 15 0.111 4 4 1.0 0
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0009889 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0009889 Not Cancer Driver No 99 0.133 206 20 0.097 0
FAM173A ANTKMT Q9BQD7 Adenine nucleotide translocase lysine N-methyltransferase chr16 GO:0009889 Not Cancer Driver No 10 0.043 37 3 0.081 0
FAM173B ATPSCKMT Q6P4H8 ATP synthase subunit C lysine N-methyltransferase chr5 GO:0009889 Not Cancer Driver No 41 0.176 10 1 0.1 0
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0009889 Not Cancer Driver No 27 0.117 48 9 0.188 0
FAM3C FAM3C Q92520 Protein FAM3C chr7 GO:0009889 Not Cancer Driver No 25 0.11 33 3 0.091 0
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:0009889 Not Cancer Driver No 74 0.104 30 2 0.067 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 GO:0009889 Not Cancer Driver No 106 0.16 6 1 0.167 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0009889 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0009889 Not Cancer Driver No 33 0.098 19 0 0.0 4
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0009889 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0009889 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0009889 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0009889 Not Cancer Driver No 41 0.128 130 22 0.169 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0009889 Not Cancer Driver No 78 0.225 29 6 0.207 0
FGF19 FGF19 O95750 Fibroblast growth factor 19 chr11 GO:0009889 Not Cancer Driver No 20 0.093 36 7 0.194 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0009889 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0009889 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0009889 Census, Compendium Yes 113 0.141 162 28 0.173 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0009889 Not Cancer Driver No 28 0.107 0 0 0.0 1
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:0009889 Not Cancer Driver No 51 0.111 0 0 0.0 10
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0009889 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLNA FLNA P21333 Filamin-A chrX GO:0009889 Census Yes 416 0.157 1456 214 0.147 28
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0009889 Not Cancer Driver No 124 0.196 327 70 0.214 3
FOS FOS P01100 Protein c-Fos chr14 GO:0009889 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0009889 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0009889 Compendium Yes 70 0.153 258 34 0.132 0
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0009889 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0009889 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0009889 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0009889 Not Cancer Driver No 38 0.088 186 16 0.086 10
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0009889 Not Cancer Driver No 31 0.24 0 0 0.0 1
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0009889 Not Cancer Driver No 67 0.133 53 10 0.189 3
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0009889 Not Cancer Driver No 92 0.171 70 13 0.186 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 GO:0009889 Not Cancer Driver No 64 0.133 384 53 0.138 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0009889 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0009889 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009889 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0009889 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0009889 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0009889 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCG GCG P01275 Pro-glucagon chr2 GO:0009889 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0009889 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0009889 Not Cancer Driver No 327 0.122 117 16 0.137 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0009889 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0009889 Not Cancer Driver No 57 0.135 199 29 0.146 2
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0009889 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0009889 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0009889 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0009889 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0009889 Not Cancer Driver No 32 0.143 77 14 0.182 0
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0009889 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0009889 Not Cancer Driver No 47 0.141 138 17 0.123 0
GLA GLA P06280 Alpha-galactosidase A chrX GO:0009889 Not Cancer Driver No 71 0.166 7 2 0.286 180
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 GO:0009889 Not Cancer Driver No 64 0.092 299 29 0.097 3
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0009889 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0009889 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLIS2 GLIS2 Q9BZE0 Zinc finger protein GLIS2 chr16 GO:0009889 Not Cancer Driver No 42 0.08 300 25 0.083 0
GMNN_ENST00000620958 GMNN O75496 Geminin chr6 GO:0009889 Not Cancer Driver No 24 0.115 206 24 0.117 1
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0009889 Not Cancer Driver No 56 0.102 257 21 0.082 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:0009889 Not Cancer Driver No 120 0.206 242 43 0.178 0
GNMT GNMT Q14749 Glycine N-methyltransferase chr6 GO:0009889 Not Cancer Driver No 25 0.085 0 0 0.0 3
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:0009889 Not Cancer Driver No 115 0.115 854 96 0.112 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0009889 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0009889 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 GO:0009889 Not Cancer Driver No 52 0.105 51 9 0.176 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0009889 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0009889 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0009889 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0009889 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0009889 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0009889 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSPT1_ENST00000563468 GSPT1 P15170 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A chr16 GO:0009889 Not Cancer Driver No 42 0.084 149 13 0.087 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0009889 Not Cancer Driver No 32 0.152 0 0 0.0 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0009889 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0009889 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0009889 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0009889 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0009889 Not Cancer Driver No 17 0.152 0 0 0.0 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0009889 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0009889 Not Cancer Driver No 59 0.159 171 32 0.187 0
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 GO:0009889 Not Cancer Driver No 96 0.121 39 3 0.077 2
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0009889 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0009889 Not Cancer Driver No 100 0.181 17 7 0.412 0
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0009889 Not Cancer Driver No 45 0.306 7 2 0.286 5
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0009889 Not Cancer Driver No 16 0.077 63 3 0.048 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0009889 Not Cancer Driver No 46 0.094 145 14 0.097 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 GO:0009889 Not Cancer Driver No 291 0.136 43 5 0.116 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0009889 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0009889 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0009889 Not Cancer Driver No 64 0.19 179 26 0.145 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0009889 Compendium Yes 233 0.32 43 16 0.372 0
HHATL HHATL Q9HCP6 Protein-cysteine N-palmitoyltransferase HHAT-like protein chr3 GO:0009889 Not Cancer Driver No 71 0.141 14 2 0.143 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0009889 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0009889 Not Cancer Driver No 37 0.106 77 9 0.117 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0009889 Census Yes 118 0.143 435 51 0.117 0
HINFP HINFP Q9BQA5 Histone H4 transcription factor chr11 GO:0009889 Not Cancer Driver No 65 0.126 154 24 0.156 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0009889 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0009889 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0009889 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0009889 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0009889 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0009889 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0009889 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0009889 Not Cancer Driver No 77 0.093 504 45 0.089 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0009889 Not Cancer Driver No 24 0.124 42 4 0.095 3
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0009889 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSD17B13 HSD17B13 Q7Z5P4 17-beta-hydroxysteroid dehydrogenase 13 chr4 GO:0009889 Not Cancer Driver No 45 0.15 0 0 0.0 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0009889 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0009889 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0009889 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0009889 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0009889 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0009889 Not Cancer Driver No 103 0.12 323 42 0.13 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0009889 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0009889 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0009889 Not Cancer Driver No 140 0.306 40 11 0.275 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0009889 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0009889 Not Cancer Driver No 107 0.109 399 45 0.113 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0009889 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0009889 Not Cancer Driver No 14 0.104 52 7 0.135 0
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0009889 Census, Compendium Yes 553 1.336 37 3 0.081 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0009889 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0009889 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0009889 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0009889 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0009889 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0009889 Not Cancer Driver No 141 0.244 298 80 0.268 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0009889 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP7 IGFBP7 Q16270 Insulin-like growth factor-binding protein 7 chr4 GO:0009889 Not Cancer Driver No 22 0.078 100 12 0.12 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0009889 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0009889 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0009889 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0009889 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0009889 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0009889 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0009889 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0009889 Not Cancer Driver No 35 0.165 58 7 0.121 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0009889 Not Cancer Driver No 49 0.153 84 12 0.143 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0009889 Not Cancer Driver No 31 0.124 108 15 0.139 0
ING5_ENST00000313552 ING5 Q8WYH8 Inhibitor of growth protein 5 chr2 GO:0009889 Not Cancer Driver No 25 0.104 119 9 0.076 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0009889 Compendium Yes 173 0.111 682 76 0.111 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0009889 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0009889 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0009889 Not Cancer Driver No 37 0.134 43 1 0.023 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 GO:0009889 Not Cancer Driver No 47 0.209 11 3 0.273 0
INSR INSR P06213 Insulin receptor chr19 GO:0009889 Not Cancer Driver No 190 0.137 280 57 0.204 64
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0009889 Not Cancer Driver No 55 0.112 43 3 0.07 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0009889 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0009889 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0009889 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0009889 Not Cancer Driver No 292 0.275 114 26 0.228 1
ITM2A ITM2A O43736 Integral membrane protein 2A chrX GO:0009889 Not Cancer Driver No 75 0.285 26 9 0.346 0
ITM2B ITM2B Q9Y287 Integral membrane protein 2B chr13 GO:0009889 Not Cancer Driver No 21 0.079 12 0 0.0 1
ITM2C ITM2C Q9NQX7 Integral membrane protein 2C chr2 GO:0009889 Not Cancer Driver No 31 0.116 33 4 0.121 0
JADE1_ENST00000512960 JADE1 Q6IE81 Protein Jade-1 chr4 GO:0009889 Not Cancer Driver No 94 0.112 409 47 0.115 0
JADE2_ENST00000395003 JADE2 Q9NQC1 E3 ubiquitin-protein ligase Jade-2 chr5 GO:0009889 Not Cancer Driver No 91 0.115 427 50 0.117 0
JADE3_ENST00000611250 JADE3 Q92613 Protein Jade-3 chrX GO:0009889 Not Cancer Driver No 110 0.134 421 52 0.124 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0009889 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0009889 Census, Compendium Yes 167 0.149 63 10 0.159 7
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0009889 Not Cancer Driver No 67 0.145 19 5 0.263 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0009889 Census Yes 35 0.106 281 25 0.089 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0009889 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0009889 Not Cancer Driver No 107 0.129 266 27 0.102 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0009889 Census Yes 97 0.159 327 47 0.144 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0009889 Not Cancer Driver No 109 0.256 40 10 0.25 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 GO:0009889 Not Cancer Driver No 131 0.113 387 48 0.124 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0009889 Census, Compendium Yes 357 0.263 275 55 0.2 2
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0009889 Census, Compendium Yes 237 0.38 57 12 0.211 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0009889 Not Cancer Driver No 84 0.118 684 81 0.118 0
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 GO:0009889 Not Cancer Driver No 57 0.111 308 38 0.123 2
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0009889 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0009889 Compendium Yes 77 0.168 366 40 0.109 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0009889 Not Cancer Driver No 38 0.176 0 0 0.0 0
LARP6 LARP6 Q9BRS8 La-related protein 6 chr15 GO:0009889 Not Cancer Driver No 64 0.13 329 48 0.146 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0009889 Not Cancer Driver No 58 0.1 350 44 0.126 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0009889 Compendium Yes 56 0.136 177 29 0.164 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0009889 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEP LEP P41159 Leptin chr7 GO:0009889 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0009889 Not Cancer Driver No 243 0.209 57 11 0.193 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0009889 Not Cancer Driver No 181 0.259 12 8 0.667 25
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0009889 Not Cancer Driver No 125 0.124 280 36 0.129 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0009889 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0009889 Not Cancer Driver No 37 0.177 86 12 0.14 0
LPAR5 LPAR5 Q9H1C0 Lysophosphatidic acid receptor 5 chr12 GO:0009889 Not Cancer Driver No 40 0.108 57 7 0.123 0
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 GO:0009889 Not Cancer Driver No 85 0.159 66 11 0.167 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0009889 Not Cancer Driver No 54 0.111 1 0 0.0 0
LPGAT1 LPGAT1 Q92604 Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 chr1 GO:0009889 Not Cancer Driver No 38 0.103 11 0 0.0 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0009889 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 GO:0009889 Not Cancer Driver No 131 0.094 18 2 0.111 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0009889 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0009889 Not Cancer Driver No 50 0.132 249 31 0.124 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0009889 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0009889 Not Cancer Driver No 22 0.086 74 4 0.054 0
MALRD1 MALRD1 Q5VYJ5 MAM and LDL-receptor class A domain-containing protein 1 chr10 GO:0009889 Not Cancer Driver No 35 0.016 130 0 0.0 0
MALSU1 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 GO:0009889 Not Cancer Driver No 17 0.073 34 0 0.0 0
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0009889 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:0009889 Census, Compendium Yes 146 0.126 1156 146 0.126 0
MAML3 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:0009889 Not Cancer Driver No 123 0.108 1119 123 0.11 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0009889 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0009889 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0009889 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0009889 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0009889 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0009889 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0009889 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0009889 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0009889 Not Cancer Driver No 51 0.108 101 12 0.119 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0009889 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0009889 Not Cancer Driver No 47 0.145 5 2 0.4 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 GO:0009889 Not Cancer Driver No 140 0.133 206 36 0.175 1
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0009889 Not Cancer Driver No 63 0.121 16 4 0.25 9
MCIDAS MCIDAS D6RGH6 Multicilin chr5 GO:0009889 Not Cancer Driver No 4 0.01 269 4 0.015 2
MDFI MDFI Q99750 MyoD family inhibitor chr6 GO:0009889 Not Cancer Driver No 25 0.102 152 15 0.099 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:0009889 Not Cancer Driver No 22 0.115 171 21 0.123 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0009889 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEN1 MEN1 O00255 Menin chr11 GO:0009889 Census, Compendium Yes 73 0.119 228 15 0.066 90
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0009889 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0009889 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0009889 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0009889 Not Cancer Driver No 74 0.128 274 29 0.106 0
METTL4 METTL4 Q8N3J2 N(6)-adenine-specific methyltransferase METTL4 chr18 GO:0009889 Not Cancer Driver No 61 0.129 34 4 0.118 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 GO:0009889 Not Cancer Driver No 35 0.054 501 24 0.048 0
MFSD12 MFSD12 Q6NUT3 Major facilitator superfamily domain-containing protein 12 chr19 GO:0009889 Not Cancer Driver No 48 0.1 24 8 0.333 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0009889 Not Cancer Driver No 61 0.112 36 4 0.111 7
MGAT4D MGAT4D A6NG13 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D chr4 GO:0009889 Not Cancer Driver No 8 0.021 14 0 0.0 0
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:0009889 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0009889 Not Cancer Driver No 23 0.126 83 6 0.072 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0009889 Not Cancer Driver No 106 0.124 554 66 0.119 0
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0009889 Not Cancer Driver No 73 0.156 115 19 0.165 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0009889 Not Cancer Driver No 300 0.305 252 77 0.306 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0009889 Not Cancer Driver No 110 0.11 101 8 0.079 0
MPV17L MPV17L Q2QL34 Mpv17-like protein chr16 GO:0009889 Not Cancer Driver No 16 0.082 3 0 0.0 0
MPV17L2 MPV17L2 Q567V2 Mpv17-like protein 2 chr19 GO:0009889 Not Cancer Driver No 22 0.107 0 0 0.0 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:0009889 Not Cancer Driver No 46 0.111 51 7 0.137 0
MRTFA_ENST00000407029 MRTFA Q969V6 Myocardin-related transcription factor A chr22 GO:0009889 Census Yes 131 0.141 843 123 0.146 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:0009889 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MST1 MST1 P26927 Hepatocyte growth factor-like protein chr3 GO:0009889 Not Cancer Driver No 110 0.155 168 19 0.113 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0009889 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0009889 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTG1 MTG1 Q9BT17 Mitochondrial ribosome-associated GTPase 1 chr10 GO:0009889 Not Cancer Driver No 43 0.129 16 3 0.188 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 GO:0009889 Not Cancer Driver No 57 0.14 47 9 0.191 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0009889 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTRF1 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 GO:0009889 Not Cancer Driver No 50 0.112 71 9 0.127 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0009889 Census Yes 40 0.032 1050 19 0.018 0
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0009889 Not Cancer Driver No 188 0.216 35 7 0.2 7
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0009889 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009889 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0009889 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0009889 Census Yes 45 0.141 246 33 0.134 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0009889 Census Yes 67 0.128 395 51 0.129 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0009889 Not Cancer Driver No 25 0.118 125 17 0.136 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0009889 Not Cancer Driver No 24 0.041 238 10 0.042 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0009889 Not Cancer Driver No 61 0.123 386 44 0.114 0
NAMPT NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 GO:0009889 Not Cancer Driver No 50 0.102 27 5 0.185 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:0009889 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0009889 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:0009889 Not Cancer Driver No 31 0.179 117 25 0.214 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0009889 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBN NBN O60934 Nibrin chr8 GO:0009889 Census Yes 90 0.119 417 54 0.129 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0009889 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0009889 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCL NCL P19338 Nucleolin chr2 GO:0009889 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0009889 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0009889 Not Cancer Driver No 94 0.133 72 11 0.153 1
NECAB1 NECAB1 Q8N987 N-terminal EF-hand calcium-binding protein 1 chr8 GO:0009889 Not Cancer Driver No 54 0.154 135 21 0.156 0
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 GO:0009889 Not Cancer Driver No 46 0.119 122 9 0.074 0
NECAB3 NECAB3 Q96P71 N-terminal EF-hand calcium-binding protein 3 chr20 GO:0009889 Not Cancer Driver No 39 0.098 169 17 0.101 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0009889 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0009889 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0009889 Not Cancer Driver No 35 0.116 23 0 0.0 0
NELFA_ENST00000411638 NELFA Q9H3P2 Negative elongation factor A chr4 GO:0009889 Not Cancer Driver No 68 0.129 373 58 0.155 0
NELFCD NELFCD Q8IXH7 Negative elongation factor C/D chr20 GO:0009889 Not Cancer Driver No 69 0.117 53 1 0.019 0
NELFE NELFE P18615 Negative elongation factor E chr6 GO:0009889 Not Cancer Driver No 47 0.124 352 45 0.128 0
NFATC3 NFATC3 Q12968 Nuclear factor of activated T-cells, cytoplasmic 3 chr16 GO:0009889 Not Cancer Driver No 112 0.104 730 80 0.11 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0009889 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0009889 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0009889 Census Yes 63 0.15 254 36 0.142 3
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0009889 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0009889 Compendium Yes 37 0.117 102 9 0.088 1
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 GO:0009889 Not Cancer Driver No 42 0.118 223 29 0.13 0
NFKBIE NFKBIE O00221 NF-kappa-B inhibitor epsilon chr6 GO:0009889 Census, Compendium Yes 41 0.082 284 16 0.056 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 GO:0009889 Not Cancer Driver No 121 0.108 491 46 0.094 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0009889 Not Cancer Driver No 57 0.133 172 25 0.145 0
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0009889 Not Cancer Driver No 26 0.089 215 21 0.098 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0009889 Not Cancer Driver No 48 0.148 181 22 0.122 55
NLN NLN Q9BYT8 Neurolysin, mitochondrial chr5 GO:0009889 Not Cancer Driver No 70 0.099 25 3 0.12 0
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0009889 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0009889 Not Cancer Driver No 310 0.292 116 43 0.371 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0009889 Not Cancer Driver No 51 0.193 5 1 0.2 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0009889 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0009889 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 GO:0009889 Not Cancer Driver No 76 0.106 54 9 0.167 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0009889 Not Cancer Driver No 59 0.123 391 41 0.105 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0009889 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0009889 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0009889 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0009889 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0009889 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0009889 Not Cancer Driver No 336 0.168 464 79 0.17 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0009889 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0009889 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPAT NPAT Q14207 Protein NPAT chr11 GO:0009889 Not Cancer Driver No 134 0.094 1149 113 0.098 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0009889 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0009889 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0009889 Not Cancer Driver No 10 0.079 82 6 0.073 0
NR0B1 NR0B1 P51843 Nuclear receptor subfamily 0 group B member 1 chrX GO:0009889 Not Cancer Driver No 106 0.226 97 18 0.186 18
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0009889 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0009889 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0009889 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0009889 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0009889 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0009889 Not Cancer Driver No 60 0.13 133 29 0.218 24
NSUN3 NSUN3 Q9H649 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial chr3 GO:0009889 Not Cancer Driver No 34 0.1 0 0 0.0 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0009889 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUGGC NUGGC Q68CJ6 Nuclear GTPase SLIP-GC chr8 GO:0009889 Not Cancer Driver No 143 0.18 141 21 0.149 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0009889 Not Cancer Driver No 90 0.105 267 31 0.116 0
OGFOD1 OGFOD1 Q8N543 Prolyl 3-hydroxylase OGFOD1 chr16 GO:0009889 Not Cancer Driver No 44 0.081 156 6 0.038 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0009889 Not Cancer Driver No 156 0.149 89 16 0.18 2
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0009889 Not Cancer Driver No 39 0.097 6 1 0.167 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0009889 Not Cancer Driver No 91 0.245 30 3 0.1 0
ORMDL1_ENST00000392350 ORMDL1 Q9P0S3 ORM1-like protein 1 chr2 GO:0009889 Not Cancer Driver No 12 0.078 0 0 0.0 0
ORMDL2_ENST00000548974 ORMDL2 Q53FV1 ORM1-like protein 2 chr12 GO:0009889 Not Cancer Driver No 10 0.065 0 0 0.0 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0009889 Not Cancer Driver No 22 0.144 9 1 0.111 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0009889 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0009889 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0009889 Not Cancer Driver No 50 0.152 10 5 0.5 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0009889 Census, Compendium Yes 100 0.157 317 55 0.174 0
PADI6 PADI6 Q6TGC4 Protein-arginine deiminase type-6 chr1 GO:0009889 Not Cancer Driver No 101 0.146 27 5 0.185 2
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX GO:0009889 Not Cancer Driver No 20 0.196 102 20 0.196 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0009889 Not Cancer Driver No 67 0.14 259 36 0.139 0
PAIP2B PAIP2B Q9ULR5 Polyadenylate-binding protein-interacting protein 2B chr2 GO:0009889 Not Cancer Driver No 16 0.13 123 16 0.13 0
PAIP2_ENST00000265192 PAIP2 Q9BPZ3 Polyadenylate-binding protein-interacting protein 2 chr5 GO:0009889 Not Cancer Driver No 11 0.087 88 10 0.114 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0009889 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAOX PAOX Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase chr10 GO:0009889 Not Cancer Driver No 70 0.137 29 0 0.0 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0009889 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:0009889 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0009889 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0009889 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0009889 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP4 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 GO:0009889 Compendium Yes 218 0.126 325 40 0.123 0
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 GO:0009889 Not Cancer Driver No 181 0.137 412 62 0.15 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0009889 Not Cancer Driver No 35 0.103 327 33 0.101 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0009889 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0009889 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0009889 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0009889 Census Yes 37 0.154 99 22 0.222 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0009889 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 GO:0009889 Not Cancer Driver No 52 0.119 50 10 0.2 0
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0009889 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0009889 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0009889 Not Cancer Driver No 70 0.17 14 2 0.143 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0009889 Not Cancer Driver No 58 0.102 199 19 0.095 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0009889 Census Yes 160 0.124 948 116 0.122 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0009889 Not Cancer Driver No 166 0.132 782 101 0.129 1
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0009889 Not Cancer Driver No 13 0.129 0 0 0.0 0
PGP PGP A6NDG6 Glycerol-3-phosphate phosphatase chr16 GO:0009889 Not Cancer Driver No 10 0.031 21 0 0.0 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0009889 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0009889 Not Cancer Driver No 154 0.145 603 93 0.154 1
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0009889 Not Cancer Driver No 83 0.11 419 45 0.107 2
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0009889 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0009889 Not Cancer Driver No 54 0.084 209 11 0.053 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0009889 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0009889 Not Cancer Driver No 278 0.133 848 101 0.119 1
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0009889 Not Cancer Driver No 57 0.098 99 13 0.131 23
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0009889 Not Cancer Driver No 66 0.201 328 66 0.201 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0009889 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0009889 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0009889 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0009889 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0009889 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0009889 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0009889 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0009889 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEK PLEK P08567 Pleckstrin chr2 GO:0009889 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 GO:0009889 Not Cancer Driver No 59 0.097 369 37 0.1 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0009889 Not Cancer Driver No 49 0.106 192 21 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0009889 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0009889 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0009889 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLR2K POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 GO:0009889 Not Cancer Driver No 10 0.172 11 1 0.091 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 GO:0009889 Not Cancer Driver No 10 0.149 0 0 0.0 0
POLR3C POLR3C Q9BUI4 DNA-directed RNA polymerase III subunit RPC3 chr1 GO:0009889 Not Cancer Driver No 60 0.112 161 21 0.13 0
POLR3F POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:0009889 Not Cancer Driver No 20 0.063 55 5 0.091 0
POLR3G POLR3G O15318 DNA-directed RNA polymerase III subunit RPC7 chr5 GO:0009889 Not Cancer Driver No 28 0.126 187 15 0.08 0
POMT1 POMT1 Q9Y6A1 Protein O-mannosyl-transferase 1 chr9 GO:0009889 Not Cancer Driver No 75 0.1 55 5 0.091 10
POMT2 POMT2 Q9UKY4 Protein O-mannosyl-transferase 2 chr14 GO:0009889 Not Cancer Driver No 84 0.112 60 3 0.05 15
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0009889 Not Cancer Driver No 62 0.092 93 4 0.043 9
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0009889 Census, Compendium Yes 113 0.178 31 6 0.194 9
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 GO:0009889 Census Yes 36 0.1 186 12 0.065 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0009889 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0009889 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0009889 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0009889 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPIL4 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 GO:0009889 Not Cancer Driver No 62 0.126 237 34 0.143 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0009889 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:0009889 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0009889 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0009889 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 GO:0009889 Not Cancer Driver No 430 0.383 807 334 0.414 1
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:0009889 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 GO:0009889 Not Cancer Driver No 37 0.117 16 0 0.0 0
PPP1R3D PPP1R3D O95685 Protein phosphatase 1 regulatory subunit 3D chr20 GO:0009889 Not Cancer Driver No 36 0.12 94 8 0.085 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:0009889 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R3F PPP1R3F Q6ZSY5 Protein phosphatase 1 regulatory subunit 3F chrX GO:0009889 Not Cancer Driver No 79 0.099 636 64 0.101 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0009889 Not Cancer Driver No 14 0.039 198 11 0.056 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0009889 Not Cancer Driver No 100 0.118 240 33 0.138 0
PPTC7 PPTC7 Q8NI37 Protein phosphatase PTC7 homolog chr12 GO:0009889 Not Cancer Driver No 32 0.105 36 2 0.056 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0009889 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0009889 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0009889 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0009889 Compendium Yes 79 0.117 43 9 0.209 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0009889 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0009889 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0009889 Compendium Yes 118 0.134 246 34 0.138 0
PRL PRL P01236 Prolactin chr6 GO:0009889 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0009889 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT3 PRMT3 O60678 Protein arginine N-methyltransferase 3 chr11 GO:0009889 Not Cancer Driver No 68 0.128 52 9 0.173 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0009889 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0009889 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0009889 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0009889 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0009889 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0009889 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0009889 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 GO:0009889 Not Cancer Driver No 86 0.145 124 25 0.202 5
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0009889 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0009889 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 GO:0009889 Not Cancer Driver No 39 0.102 74 2 0.027 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0009889 Not Cancer Driver No 150 0.126 640 77 0.12 3
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0009889 Not Cancer Driver No 51 0.102 186 22 0.118 0
PXYLP1 PXYLP1 Q8TE99 2-phosphoxylose phosphatase 1 chr3 GO:0009889 Not Cancer Driver No 63 0.131 32 13 0.406 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0009889 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB38 RAB38 P57729 Ras-related protein Rab-38 chr11 GO:0009889 Not Cancer Driver No 27 0.128 0 0 0.0 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0009889 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0009889 Not Cancer Driver No 168 0.121 143 17 0.119 2
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 GO:0009889 Not Cancer Driver No 37 0.157 1 0 0.0 1
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0009889 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:0009889 Not Cancer Driver No 16 0.108 0 0 0.0 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0009889 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0009889 Not Cancer Driver No 216 0.144 803 116 0.144 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0009889 Census, Compendium Yes 70 0.152 167 14 0.084 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:0009889 Not Cancer Driver No 31 0.128 40 6 0.15 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0009889 Census, Compendium Yes 140 0.151 282 32 0.113 22
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 GO:0009889 Not Cancer Driver No 202 0.127 578 75 0.13 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0009889 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0009889 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:0009889 Not Cancer Driver No 40 0.11 129 12 0.093 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0009889 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0009889 Not Cancer Driver No 158 0.139 796 115 0.144 0
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0009889 Not Cancer Driver No 19 0.041 87 7 0.08 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0009889 Not Cancer Driver No 37 0.185 24 5 0.208 0
RD3 RD3 Q7Z3Z2 Protein RD3 chr1 GO:0009889 Not Cancer Driver No 46 0.236 75 21 0.28 0
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0009889 Not Cancer Driver No 33 0.097 8 0 0.0 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0009889 Not Cancer Driver No 132 0.133 495 71 0.143 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0009889 Compendium Yes 75 0.136 400 48 0.12 0
RELN RELN P78509 Reelin chr7 GO:0009889 Not Cancer Driver No 761 0.22 107 19 0.178 7
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0009889 Not Cancer Driver No 142 0.129 868 113 0.13 4
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0009889 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0009889 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0009889 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0009889 Not Cancer Driver No 38 0.112 20 1 0.05 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0009889 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGN RGN Q15493 Regucalcin chrX GO:0009889 Not Cancer Driver No 38 0.127 14 3 0.214 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0009889 Not Cancer Driver No 57 0.101 309 37 0.12 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0009889 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0009889 Not Cancer Driver No 20 0.146 3 0 0.0 0
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 GO:0009889 Not Cancer Driver No 46 0.102 83 11 0.133 1
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0009889 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0009889 Not Cancer Driver No 56 0.115 226 29 0.128 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0009889 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0009889 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:0009889 Not Cancer Driver No 56 0.092 293 25 0.085 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 GO:0009889 Not Cancer Driver No 27 0.133 33 2 0.061 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 GO:0009889 Census, Compendium Yes 26 0.203 15 1 0.067 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0009889 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPRD1A RPRD1A Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A chr18 GO:0009889 Not Cancer Driver No 49 0.157 86 16 0.186 0
RPRD1B RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 GO:0009889 Not Cancer Driver No 34 0.104 155 16 0.103 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0009889 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0009889 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0009889 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0009889 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:0009889 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0009889 Not Cancer Driver No 176 0.132 241 21 0.087 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0009889 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0009889 Not Cancer Driver No 54 0.143 97 15 0.155 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0009889 Not Cancer Driver No 66 0.145 270 44 0.163 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0009889 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0009889 Not Cancer Driver No 83 0.159 447 73 0.163 47
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:0009889 Not Cancer Driver No 28 0.115 168 19 0.113 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0009889 Not Cancer Driver No 18 0.158 76 7 0.092 0
SAMD8 SAMD8 Q96LT4 Sphingomyelin synthase-related protein 1 chr10 GO:0009889 Not Cancer Driver No 40 0.096 0 0 0.0 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 GO:0009889 Not Cancer Driver No 162 0.141 938 132 0.141 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:0009889 Not Cancer Driver No 155 0.122 939 118 0.126 0
SCAP SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 GO:0009889 Not Cancer Driver No 145 0.113 329 36 0.109 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0009889 Not Cancer Driver No 53 0.096 6 1 0.167 0
SDHAF3 SDHAF3 Q9NRP4 Succinate dehydrogenase assembly factor 3, mitochondrial chr7 GO:0009889 Not Cancer Driver No 18 0.144 65 5 0.077 0
SEC14L2 SEC14L2 O76054 SEC14-like protein 2 chr22 GO:0009889 Not Cancer Driver No 30 0.074 67 5 0.075 0
SECISBP2 SECISBP2 Q96T21 Selenocysteine insertion sequence-binding protein 2 chr9 GO:0009889 Not Cancer Driver No 90 0.105 565 50 0.088 1
SECISBP2L SECISBP2L Q93073 Selenocysteine insertion sequence-binding protein 2-like chr15 GO:0009889 Not Cancer Driver No 142 0.129 871 111 0.127 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0009889 Not Cancer Driver No 7 0.037 122 6 0.049 0
SELENOT SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:0009889 Not Cancer Driver No 25 0.128 0 0 0.0 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0009889 Not Cancer Driver No 73 0.124 285 38 0.133 0
SEPSECS SEPSECS Q9HD40 O-phosphoseryl-tRNA(Sec) selenium transferase chr4 GO:0009889 Not Cancer Driver No 47 0.094 22 7 0.318 3
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:0009889 Not Cancer Driver No 90 0.217 22 3 0.136 0
SERPINB7 SERPINB7 O75635 Serpin B7 chr18 GO:0009889 Not Cancer Driver No 100 0.263 30 8 0.267 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0009889 Not Cancer Driver No 62 0.126 112 21 0.188 1
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0009889 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0009889 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 GO:0009889 Not Cancer Driver No 110 0.172 627 106 0.169 0
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:0009889 Census, Compendium Yes 244 0.187 477 80 0.168 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0009889 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 GO:0009889 Not Cancer Driver No 57 0.113 58 5 0.086 1
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0009889 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0009889 Compendium Yes 172 0.135 617 73 0.118 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0009889 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009889 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0009889 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0009889 Not Cancer Driver No 33 0.083 60 2 0.033 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0009889 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT5 SIRT5 Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 GO:0009889 Not Cancer Driver No 41 0.132 55 7 0.127 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0009889 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 GO:0009889 Not Cancer Driver No 105 0.204 23 7 0.304 1
SLC24A5 SLC24A5 Q71RS6 Sodium/potassium/calcium exchanger 5 chr15 GO:0009889 Not Cancer Driver No 79 0.158 7 2 0.286 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0009889 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0009889 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC25A37 SLC25A37 Q9NYZ2 Mitoferrin-1 chr8 GO:0009889 Not Cancer Driver No 45 0.133 68 5 0.074 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0009889 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0009889 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0009889 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC35B4 SLC35B4 Q969S0 UDP-xylose and UDP-N-acetylglucosamine transporter chr7 GO:0009889 Not Cancer Driver No 27 0.082 10 1 0.1 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0009889 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:0009889 Not Cancer Driver No 63 0.11 48 3 0.062 12
SLC45A3 SLC45A3 Q96JT2 Solute carrier family 45 member 3 chr1 GO:0009889 Census, Compendium Yes 75 0.136 25 6 0.24 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0009889 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC5A3 SLC5A3 P53794 Sodium/myo-inositol cotransporter chr21 GO:0009889 Not Cancer Driver No 81 0.113 73 6 0.082 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0009889 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0009889 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0009889 Not Cancer Driver No 177 0.196 34 8 0.235 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0009889 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0009889 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0009889 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0009889 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0009889 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0009889 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0009889 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0009889 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0009889 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0009889 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0009889 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0009889 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0009889 Not Cancer Driver No 166 0.117 751 97 0.129 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0009889 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0009889 Not Cancer Driver No 82 0.184 216 52 0.241 0
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0009889 Not Cancer Driver No 92 0.14 224 29 0.129 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0009889 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0009889 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0009889 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 GO:0009889 Not Cancer Driver No 73 0.133 49 4 0.082 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0009889 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0009889 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0009889 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0009889 Compendium Yes 86 0.169 495 82 0.166 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0009889 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0009889 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0009889 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0009889 Not Cancer Driver No 46 0.17 187 34 0.182 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0009889 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0009889 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0009889 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0009889 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRI SRI P30626 Sorcin chr7 GO:0009889 Not Cancer Driver No 15 0.076 32 2 0.062 0
SRP9 SRP9 P49458 Signal recognition particle 9 kDa protein chr1 GO:0009889 Not Cancer Driver No 14 0.163 4 1 0.25 0
SRRD SRRD Q9UH36 SRR1-like protein chr22 GO:0009889 Not Cancer Driver No 30 0.088 64 3 0.047 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:0009889 Not Cancer Driver No 27 0.182 0 0 0.0 6
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:0009889 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0009889 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0009889 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:0009889 Not Cancer Driver No 8 0.041 8 0 0.0 0
STAR STAR P49675 Steroidogenic acute regulatory protein, mitochondrial chr8 GO:0009889 Not Cancer Driver No 45 0.158 85 10 0.118 7
STARD4_ENST00000505803 STARD4 Q96DR4 StAR-related lipid transfer protein 4 chr5 GO:0009889 Not Cancer Driver No 48 0.234 0 0 0.0 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0009889 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0009889 Census, Compendium Yes 110 0.143 152 15 0.099 19
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0009889 Not Cancer Driver No 71 0.235 112 29 0.259 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0009889 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK36_ENST00000440309 STK36 Q9NRP7 Serine/threonine-protein kinase 36 chr2 GO:0009889 Not Cancer Driver No 167 0.127 250 36 0.144 0
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:0009889 Not Cancer Driver No 41 0.111 27 2 0.074 2
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0009889 Not Cancer Driver No 40 0.112 117 9 0.077 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0009889 Not Cancer Driver No 121 0.122 659 83 0.126 2
SUCO_ENST00000263688 SUCO Q9UBS9 SUN domain-containing ossification factor chr1 GO:0009889 Not Cancer Driver No 164 0.131 785 99 0.126 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0009889 Census Yes 55 0.114 199 19 0.095 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0009889 Not Cancer Driver No 10 0.099 76 7 0.092 0
SUPT4H1_ENST00000580947 SUPT4H1 P63272 Transcription elongation factor SPT4 chr17 GO:0009889 Not Cancer Driver No 15 0.128 0 0 0.0 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 GO:0009889 Not Cancer Driver No 165 0.152 572 87 0.152 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0009889 Not Cancer Driver No 59 0.143 15 1 0.067 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0009889 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0009889 Not Cancer Driver No 93 0.149 285 39 0.137 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 GO:0009889 Not Cancer Driver No 21 0.071 111 2 0.018 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0009889 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0009889 Not Cancer Driver No 40 0.115 258 31 0.12 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0009889 Not Cancer Driver No 51 0.123 202 15 0.074 27
TAZ_ENST00000612460 TAFAZZIN Q16635 Tafazzin chrX GO:0009889 Not Cancer Driver No 33 0.126 12 0 0.0 10
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0009889 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0009889 Not Cancer Driver No 110 0.253 253 69 0.273 1
TCERG1 TCERG1 O14776 Transcription elongation regulator 1 chr5 GO:0009889 Not Cancer Driver No 143 0.13 811 110 0.136 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0009889 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0009889 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0009889 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0009889 Not Cancer Driver No 52 0.122 157 24 0.153 1
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0009889 Not Cancer Driver No 6 0.049 8 4 0.5 0
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0009889 Not Cancer Driver No 728 0.267 482 164 0.34 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0009889 Not Cancer Driver No 106 0.137 442 43 0.097 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0009889 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0009889 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0009889 Census Yes 110 0.097 212 16 0.075 31
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0009889 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 GO:0009889 Not Cancer Driver No 82 0.2 245 47 0.192 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0009889 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0009889 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0009889 Not Cancer Driver No 45 0.109 96 14 0.146 1
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0009889 Not Cancer Driver No 69 0.141 207 30 0.145 2
THRSP THRSP Q92748 Thyroid hormone-inducible hepatic protein chr11 GO:0009889 Not Cancer Driver No 28 0.192 47 7 0.149 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0009889 Not Cancer Driver No 92 0.129 443 66 0.149 1
TICRR TICRR Q7Z2Z1 Treslin chr15 GO:0009889 Not Cancer Driver No 201 0.105 1308 129 0.099 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0009889 Not Cancer Driver No 154 0.127 367 51 0.139 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 GO:0009889 Not Cancer Driver No 38 0.084 190 17 0.089 4
TIPIN TIPIN Q9BVW5 TIMELESS-interacting protein chr15 GO:0009889 Not Cancer Driver No 26 0.086 242 19 0.079 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0009889 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0009889 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0009889 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0009889 Not Cancer Driver No 141 0.137 35 3 0.086 0
TM9SF2 TM9SF2 Q99805 Transmembrane 9 superfamily member 2 chr13 GO:0009889 Not Cancer Driver No 82 0.124 16 2 0.125 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0009889 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0009889 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEFF2 TMEFF2 Q9UIK5 Tomoregulin-2 chr2 GO:0009889 Not Cancer Driver No 81 0.217 68 8 0.118 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0009889 Not Cancer Driver No 26 0.099 9 1 0.111 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 GO:0009889 Not Cancer Driver No 10 0.101 0 0 0.0 0
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 GO:0009889 Not Cancer Driver No 13 0.114 0 0 0.0 0
TMEM14C_ENST00000229563 TMEM14C Q9P0S9 Transmembrane protein 14C chr6 GO:0009889 Not Cancer Driver No 9 0.08 0 0 0.0 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 GO:0009889 Not Cancer Driver No 39 0.121 26 3 0.115 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0009889 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009889 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0009889 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0009889 Not Cancer Driver No 117 0.1 255 24 0.094 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 GO:0009889 Not Cancer Driver No 284 0.145 1830 265 0.145 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 GO:0009889 Not Cancer Driver No 205 0.112 1735 195 0.112 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 GO:0009889 Not Cancer Driver No 170 0.101 1564 162 0.104 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0009889 Not Cancer Driver No 35 0.101 214 18 0.084 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0009889 Not Cancer Driver No 51 0.107 268 29 0.108 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0009889 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0009889 Census Yes 311 0.132 1990 266 0.134 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:0009889 Not Cancer Driver No 74 0.105 110 11 0.1 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0009889 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0009889 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0009889 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0009889 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRNAU1AP TRNAU1AP Q9NX07 tRNA selenocysteine 1-associated protein 1 chr1 GO:0009889 Not Cancer Driver No 28 0.098 32 4 0.125 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0009889 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0009889 Not Cancer Driver No 37 0.112 73 7 0.096 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 GO:0009889 Not Cancer Driver No 37 0.114 74 7 0.095 2
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0009889 Not Cancer Driver No 5 0.03 1 0 0.0 0
TSSK4_ENST00000287913 TSSK4 Q6SA08 Testis-specific serine/threonine-protein kinase 4 chr14 GO:0009889 Not Cancer Driver No 29 0.088 8 1 0.125 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0009889 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0009889 Not Cancer Driver No 159 0.106 659 74 0.112 0
TYRP1 TYRP1 P17643 5,6-dihydroxyindole-2-carboxylic acid oxidase chr9 GO:0009889 Not Cancer Driver No 81 0.151 87 13 0.149 2
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0009889 Not Cancer Driver No 100 0.131 567 77 0.136 1
UCN UCN P55089 Urocortin chr2 GO:0009889 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0009889 Not Cancer Driver No 43 0.14 1 0 0.0 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0009889 Not Cancer Driver No 142 0.135 588 77 0.131 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 GO:0009889 Not Cancer Driver No 79 0.098 511 46 0.09 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0009889 Not Cancer Driver No 146 0.129 329 36 0.109 0
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:0009889 Not Cancer Driver No 10 0.079 41 1 0.024 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0009889 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0009889 Not Cancer Driver No 30 0.087 326 29 0.089 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0009889 Not Cancer Driver No 98 0.119 394 42 0.107 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0009889 Not Cancer Driver No 170 0.154 215 45 0.209 0
UTP15 UTP15 Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog chr5 GO:0009889 Not Cancer Driver No 49 0.095 39 4 0.103 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0009889 Not Cancer Driver No 88 0.109 186 16 0.086 16
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0009889 Not Cancer Driver No 27 0.116 41 7 0.171 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0009889 Census, Compendium Yes 142 0.667 117 36 0.308 133
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0009889 Not Cancer Driver No 84 0.18 316 57 0.18 1
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0009889 Not Cancer Driver No 68 0.085 99 9 0.091 1
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 GO:0009889 Not Cancer Driver No 57 0.084 216 18 0.083 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 GO:0009889 Not Cancer Driver No 30 0.09 35 3 0.086 0
WDR75 WDR75 Q8IWA0 WD repeat-containing protein 75 chr2 GO:0009889 Not Cancer Driver No 67 0.081 87 7 0.08 0
WDTC1 WDTC1 Q8N5D0 WD and tetratricopeptide repeats protein 1 chr1 GO:0009889 Not Cancer Driver No 81 0.12 154 21 0.136 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0009889 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0009889 Not Cancer Driver No 66 0.174 0 0 0.0 2
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0009889 Not Cancer Driver No 66 0.12 232 29 0.125 4
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 GO:0009889 Not Cancer Driver No 50 0.075 292 7 0.024 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0009889 Not Cancer Driver No 19 0.073 169 9 0.053 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0009889 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0009889 Not Cancer Driver No 213 0.125 577 65 0.113 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0009889 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX2 YBX2 Q9Y2T7 Y-box-binding protein 2 chr17 GO:0009889 Not Cancer Driver No 48 0.132 342 46 0.135 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0009889 Not Cancer Driver No 49 0.132 359 47 0.131 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0009889 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0009889 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0009889 Not Cancer Driver No 74 0.126 409 51 0.125 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0009889 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0009889 Compendium Yes 151 0.204 433 80 0.185 4
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0009889 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:0009889 Not Cancer Driver No 48 0.091 314 18 0.057 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0009889 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZCCHC13 ZCCHC13 Q8WW36 Zinc finger CCHC domain-containing protein 13 chrX GO:0009889 Not Cancer Driver No 44 0.265 13 5 0.385 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0009889 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0009889 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0009889 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0009889 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0009889 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:0009889 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZNF205_ENST00000382192 ZNF205 O95201 Zinc finger protein 205 chr16 GO:0009889 Not Cancer Driver No 74 0.134 367 49 0.134 0
ZNF345_ENST00000612719 ZNF345 Q14585 Zinc finger protein 345 chr19 GO:0009889 Not Cancer Driver No 101 0.207 107 21 0.196 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0009889 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF451 ZNF451 Q9Y4E5 E3 SUMO-protein ligase ZNF451 chr6 GO:0009889 Not Cancer Driver No 169 0.159 191 25 0.131 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 GO:0009889 Not Cancer Driver No 101 0.113 694 83 0.12 0
ZNF692_ENST00000306601 ZNF692 Q9BU19 Zinc finger protein 692 chr1 GO:0009889 Not Cancer Driver No 70 0.135 302 42 0.139 0
ZNF76 ZNF76 P36508 Zinc finger protein 76 chr6 GO:0009889 Not Cancer Driver No 66 0.116 330 39 0.118 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:0009889 Not Cancer Driver No 39 0.105 312 37 0.119 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0009889 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZRANB3 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:0009889 Not Cancer Driver No 126 0.117 261 31 0.119 0