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Total number of protein in "GO:0006950" GO term:  1058

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0006950 Not Cancer Driver No 260 0.176 144 22 0.153 0
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0006950 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0006950 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0006950 Not Cancer Driver No 46 0.126 248 31 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0006950 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABRAXAS2 ABRAXAS2 Q15018 BRISC complex subunit Abraxas 2 chr10 GO:0006950 Not Cancer Driver No 47 0.113 207 26 0.126 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0006950 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0006950 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0006950 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 GO:0006950 Not Cancer Driver No 94 0.121 172 19 0.11 5
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0006950 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0006950 Not Cancer Driver No 63 0.104 163 23 0.141 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0006950 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0006950 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0006950 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0006950 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0006950 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0006950 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADH5 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 GO:0006950 Not Cancer Driver No 36 0.096 2 1 0.5 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0006950 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0006950 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0006950 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0006950 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0006950 Not Cancer Driver No 32 0.088 49 4 0.082 1
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0006950 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB1 ADRB1 P08588 Beta-1 adrenergic receptor chr10 GO:0006950 Not Cancer Driver No 35 0.073 116 1 0.009 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0006950 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGAP3_ENST00000622464 AGAP3 Q96P47 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 chr7 GO:0006950 Not Cancer Driver No 116 0.133 404 55 0.136 0
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 GO:0006950 Not Cancer Driver No 74 0.202 131 41 0.313 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0006950 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0006950 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 GO:0006950 Not Cancer Driver No 107 0.118 537 67 0.125 0
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0006950 Not Cancer Driver No 52 0.165 19 1 0.053 0
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0006950 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0006950 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0006950 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0006950 Not Cancer Driver No 194 0.117 353 36 0.102 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0006950 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0006950 Not Cancer Driver No 34 0.094 192 18 0.094 0
ANKZF1 ANKZF1 Q9H8Y5 Ankyrin repeat and zinc finger domain-containing protein 1 chr2 GO:0006950 Not Cancer Driver No 77 0.106 507 57 0.112 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0006950 Not Cancer Driver No 59 0.171 61 12 0.197 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0006950 Not Cancer Driver No 161 0.214 98 26 0.265 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0006950 Not Cancer Driver No 127 0.102 17 1 0.059 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0006950 Not Cancer Driver No 73 0.327 0 0 0.0 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006950 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0006950 Not Cancer Driver No 64 0.125 407 57 0.14 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0006950 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0006950 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0006950 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0006950 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0006950 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOL1_ENST00000397279 APOL1 O14791 Apolipoprotein L1 chr22 GO:0006950 Not Cancer Driver No 51 0.128 82 9 0.11 2
APOL2 APOL2 Q9BQE5 Apolipoprotein L2 chr22 GO:0006950 Not Cancer Driver No 34 0.101 94 8 0.085 0
APOPT1 COA8 Q96IL0 Cytochrome c oxidase assembly factor 8 chr14 GO:0006950 Not Cancer Driver No 23 0.112 48 4 0.083 0
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0006950 Not Cancer Driver No 70 0.105 149 14 0.094 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0006950 Not Cancer Driver No 36 0.101 101 6 0.059 9
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0006950 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP2 AQP2 P41181 Aquaporin-2 chr12 GO:0006950 Not Cancer Driver No 52 0.192 31 3 0.097 28
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0006950 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP5 AQP5 P55064 Aquaporin-5 chr12 GO:0006950 Not Cancer Driver No 31 0.117 21 2 0.095 5
AREG AREG P15514 Amphiregulin chr4 GO:0006950 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0006950 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARHGEF10L ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0006950 Census, Compendium Yes 155 0.121 431 47 0.109 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0006950 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 GO:0006950 Not Cancer Driver No 28 0.151 0 0 0.0 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0006950 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0006950 Not Cancer Driver No 71 0.113 332 40 0.12 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0006950 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0006950 Not Cancer Driver No 81 0.144 11 0 0.0 3
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0006950 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 GO:0006950 Not Cancer Driver No 66 0.104 269 24 0.089 2
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0006950 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0006950 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0006950 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0006950 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0006950 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATG10 ATG10 Q9H0Y0 Ubiquitin-like-conjugating enzyme ATG10 chr5 GO:0006950 Not Cancer Driver No 22 0.1 9 1 0.111 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0006950 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0006950 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0006950 Compendium Yes 77 0.11 53 8 0.151 6
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0006950 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0006950 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0006950 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0006950 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0006950 Not Cancer Driver No 130 0.13 147 16 0.109 0
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0006950 Not Cancer Driver No 8 0.075 85 7 0.082 0
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0006950 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0006950 Not Cancer Driver No 41 0.1 122 13 0.107 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0006950 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0006950 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0006950 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0006950 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0006950 Not Cancer Driver No 42 0.167 53 13 0.245 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0006950 Not Cancer Driver No 38 0.095 129 13 0.101 0
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 GO:0006950 Not Cancer Driver No 105 0.143 328 39 0.119 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0006950 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0006950 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0006950 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0006950 Not Cancer Driver No 38 0.18 58 9 0.155 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0006950 Not Cancer Driver No 28 0.224 119 25 0.21 0
BATF2 BATF2 Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 chr11 GO:0006950 Not Cancer Driver No 28 0.102 202 19 0.094 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0006950 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0006950 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0006950 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0006950 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0006950 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0006950 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0006950 Census Yes 44 0.097 259 23 0.089 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0006950 Census, Compendium Yes 421 0.458 899 408 0.454 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0006950 Not Cancer Driver No 81 0.207 0 0 0.0 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0006950 Not Cancer Driver No 45 0.1 190 19 0.1 0
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0006950 Not Cancer Driver No 12 0.063 183 12 0.066 0
BPIFB1 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 GO:0006950 Not Cancer Driver No 93 0.192 7 0 0.0 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0006950 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 GO:0006950 Not Cancer Driver No 171 0.162 425 68 0.16 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0006950 Not Cancer Driver No 273 0.359 36 17 0.472 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0006950 Census Yes 174 0.139 397 59 0.149 6
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0006950 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0006950 Not Cancer Driver No 90 0.122 321 39 0.121 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0006950 Census, Compendium Yes 147 0.223 114 27 0.237 110
BVES BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0006950 Not Cancer Driver No 59 0.164 65 15 0.231 1
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:0006950 Not Cancer Driver No 61 0.137 35 6 0.171 0
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 GO:0006950 Not Cancer Driver No 91 0.136 632 88 0.139 0
C2orf40 ECRG4 Q9H1Z8 Augurin chr2 GO:0006950 Not Cancer Driver No 37 0.25 23 11 0.478 0
C3 C3 P01024 Complement C3 chr19 GO:0006950 Not Cancer Driver No 337 0.203 287 50 0.174 12
C5 C5 P01031 Complement C5 chr9 GO:0006950 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0006950 Not Cancer Driver No 71 0.203 0 0 0.0 0
C7 C7 P10643 Complement component C7 chr5 GO:0006950 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0006950 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0006950 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0006950 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0006950 Not Cancer Driver No 156 0.279 40 8 0.2 2
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0006950 Not Cancer Driver No 31 0.091 43 5 0.116 0
CALR CALR P27797 Calreticulin chr19 GO:0006950 Census Yes 45 0.108 245 31 0.127 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0006950 Not Cancer Driver No 83 0.174 62 10 0.161 7
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0006950 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0006950 Not Cancer Driver No 25 0.147 48 4 0.083 0
CAMTA2_ENST00000348066 CAMTA2 O94983 Calmodulin-binding transcription activator 2 chr17 GO:0006950 Not Cancer Driver No 148 0.123 613 84 0.137 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0006950 Not Cancer Driver No 81 0.116 46 11 0.239 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0006950 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0006950 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0006950 Not Cancer Driver No 72 0.134 225 35 0.156 11
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0006950 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0006950 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0006950 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0006950 Census Yes 49 0.118 71 7 0.099 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0006950 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAT CAT P04040 Catalase chr11 GO:0006950 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0006950 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0006950 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0006950 Not Cancer Driver No 61 0.111 160 19 0.119 103
CCDC47_ENST00000403162 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 GO:0006950 Not Cancer Driver No 49 0.101 265 23 0.087 0
CCDC88B CCDC88B A6NC98 Coiled-coil domain-containing protein 88B chr11 GO:0006950 Not Cancer Driver No 156 0.106 1152 130 0.113 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0006950 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0006950 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0006950 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR3_ENST00000357422 CCR3 P51677 C-C chemokine receptor type 3 chr3 GO:0006950 Not Cancer Driver No 84 0.237 0 0 0.0 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0006950 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0006950 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR9 CCR9 P51686 C-C chemokine receptor type 9 chr3 GO:0006950 Not Cancer Driver No 60 0.163 0 0 0.0 0
CD163 CD163 Q86VB7 Scavenger receptor cysteine-rich type 1 protein M130 chr12 GO:0006950 Not Cancer Driver No 359 0.311 68 27 0.397 0
CD300C CD300C Q08708 CMRF35-like molecule 6 chr17 GO:0006950 Not Cancer Driver No 67 0.299 85 24 0.282 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0006950 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0006950 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0006950 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD5L CD5L O43866 CD5 antigen-like chr1 GO:0006950 Not Cancer Driver No 145 0.418 33 13 0.394 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0006950 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD68 CD68 P34810 Macrosialin chr17 GO:0006950 Not Cancer Driver No 26 0.073 192 13 0.068 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 GO:0006950 Not Cancer Driver No 52 0.138 214 31 0.145 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0006950 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0006950 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0006950 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0006950 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0006950 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0006950 Not Cancer Driver No 15 0.109 67 3 0.045 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0006950 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0006950 Not Cancer Driver No 13 0.087 141 12 0.085 0
CFB CFB P00751 Complement factor B chr6 GO:0006950 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0006950 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0006950 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR1 CFHR1 Q03591 Complement factor H-related protein 1 chr1 GO:0006950 Not Cancer Driver No 68 0.206 42 11 0.262 0
CFHR2 CFHR2 P36980 Complement factor H-related protein 2 chr1 GO:0006950 Not Cancer Driver No 97 0.359 14 8 0.571 0
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0006950 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFP CFP P27918 Properdin chrX GO:0006950 Not Cancer Driver No 60 0.128 48 7 0.146 6
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0006950 Not Cancer Driver No 30 0.135 49 5 0.102 0
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0006950 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0006950 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0006950 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0006950 Not Cancer Driver No 25 0.113 137 13 0.095 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0006950 Not Cancer Driver No 74 0.099 116 9 0.078 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0006950 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0006950 Not Cancer Driver No 43 0.196 32 3 0.094 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0006950 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0006950 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLEC2A CLEC2A Q6UVW9 C-type lectin domain family 2 member A chr12 GO:0006950 Not Cancer Driver No 10 0.057 0 0 0.0 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 GO:0006950 Not Cancer Driver No 35 0.148 22 4 0.182 0
CLEC4C_ENST00000360345 CLEC4C Q8WTT0 C-type lectin domain family 4 member C chr12 GO:0006950 Not Cancer Driver No 58 0.272 5 1 0.2 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0006950 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0006950 Not Cancer Driver No 56 0.256 5 2 0.4 0
CLEC5A CLEC5A Q9NY25 C-type lectin domain family 5 member A chr7 GO:0006950 Not Cancer Driver No 46 0.245 0 0 0.0 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0006950 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0006950 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0006950 Not Cancer Driver No 45 0.157 16 2 0.125 16
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 GO:0006950 Not Cancer Driver No 69 0.098 224 25 0.112 11
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0006950 Not Cancer Driver No 69 0.154 156 27 0.173 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0006950 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0006950 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0006950 Not Cancer Driver No 72 0.266 158 40 0.253 2
COMT COMT P21964 Catechol O-methyltransferase chr22 GO:0006950 Not Cancer Driver No 21 0.077 5 0 0.0 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0006950 Not Cancer Driver No 85 0.117 443 54 0.122 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0006950 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0006950 Not Cancer Driver No 273 0.264 85 28 0.329 0
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:0006950 Not Cancer Driver No 35 0.176 45 5 0.111 1
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0006950 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0006950 Not Cancer Driver No 96 0.208 338 67 0.198 1
CRK CRK P46108 Adapter molecule crk chr17 GO:0006950 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRP CRP P02741 C-reactive protein chr1 GO:0006950 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0006950 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0006950 Not Cancer Driver No 72 0.121 100 12 0.12 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0006950 Not Cancer Driver No 22 0.126 59 11 0.186 4
CRYGD CRYGD P07320 Gamma-crystallin D chr2 GO:0006950 Not Cancer Driver No 28 0.161 0 0 0.0 6
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0006950 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0006950 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0006950 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSPG5 CSPG5 O95196 Chondroitin sulfate proteoglycan 5 chr3 GO:0006950 Not Cancer Driver No 75 0.133 397 46 0.116 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0006950 Census Yes 126 0.139 268 35 0.131 4
CTSG CTSG P08311 Cathepsin G chr14 GO:0006950 Not Cancer Driver No 65 0.255 80 29 0.362 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0006950 Not Cancer Driver No 138 0.151 207 38 0.184 2
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0006950 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0006950 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0006950 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0006950 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0006950 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0006950 Not Cancer Driver No 87 0.242 8 0 0.0 0
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0006950 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0006950 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0006950 Not Cancer Driver No 87 0.176 21 6 0.286 0
CYSLTR1 CYSLTR1 Q9Y271 Cysteinyl leukotriene receptor 1 chrX GO:0006950 Not Cancer Driver No 58 0.172 8 1 0.125 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0006950 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0006950 Not Cancer Driver No 102 0.114 485 61 0.126 4
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0006950 Not Cancer Driver No 193 0.135 114 11 0.096 0
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0006950 Not Cancer Driver No 125 0.203 71 17 0.239 3
DCDC2 DCDC2 Q9UHG0 Doublecortin domain-containing protein 2 chr6 GO:0006950 Not Cancer Driver No 72 0.151 264 41 0.155 2
DCD_ENST00000293371 DCD P81605 Dermcidin chr12 GO:0006950 Not Cancer Driver No 25 0.227 67 19 0.284 0
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0006950 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0006950 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0006950 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0006950 Not Cancer Driver No 14 0.082 88 9 0.102 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0006950 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0006950 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0006950 Census Yes 29 0.172 160 27 0.169 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0006950 Not Cancer Driver No 118 0.128 61 10 0.164 2
DEFA3 DEFA3 P59666 Neutrophil defensin 3 chr8 GO:0006950 Not Cancer Driver No 15 0.16 0 0 0.0 0
DEFA4 DEFA4 P12838 Defensin alpha 4 chr8 GO:0006950 Not Cancer Driver No 35 0.361 17 5 0.294 0
DEFA5 DEFA5 Q01523 Defensin-5 chr8 GO:0006950 Not Cancer Driver No 16 0.17 17 3 0.176 0
DEFA6 DEFA6 Q01524 Defensin-6 chr8 GO:0006950 Not Cancer Driver No 19 0.19 15 2 0.133 0
DEFB1 DEFB1 P60022 Beta-defensin 1 chr8 GO:0006950 Not Cancer Driver No 8 0.118 0 0 0.0 0
DEFB106B DEFB106B Q8N104 Beta-defensin 106 chr8 GO:0006950 Not Cancer Driver No 15 0.231 0 0 0.0 0
DEFB114 DEFB114 Q30KQ6 Beta-defensin 114 chr6 GO:0006950 Not Cancer Driver No 31 0.449 0 0 0.0 0
DEFB119_ENST00000376321 DEFB119 Q8N690 Beta-defensin 119 chr20 GO:0006950 Not Cancer Driver No 25 0.298 0 0 0.0 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0006950 Not Cancer Driver No 28 0.112 11 1 0.091 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0006950 Not Cancer Driver No 16 0.086 12 2 0.167 2
DLEC1 DLEC1 Q9Y238 Deleted in lung and esophageal cancer protein 1 chr3 GO:0006950 Not Cancer Driver No 220 0.125 416 66 0.159 0
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 GO:0006950 Not Cancer Driver No 506 0.21 404 64 0.158 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0006950 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:0006950 Census, Compendium Yes 35 0.103 196 26 0.133 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 GO:0006950 Not Cancer Driver No 110 0.139 36 3 0.083 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0006950 Not Cancer Driver No 60 0.119 131 17 0.13 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0006950 Not Cancer Driver No 151 0.197 8 1 0.125 0
DPYSL3_ENST00000398514 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 GO:0006950 Not Cancer Driver No 93 0.163 128 14 0.109 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0006950 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0006950 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0006950 Not Cancer Driver No 26 0.062 109 0 0.0 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0006950 Not Cancer Driver No 43 0.113 39 3 0.077 4
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0006950 Not Cancer Driver No 122 0.134 554 70 0.126 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0006950 Not Cancer Driver No 104 0.114 284 33 0.116 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0006950 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0006950 Not Cancer Driver No 69 0.119 54 3 0.056 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0006950 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0006950 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0006950 Not Cancer Driver No 104 0.143 311 39 0.125 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0006950 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0006950 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2A EIF2A Q9BY44 Eukaryotic translation initiation factor 2A chr3 GO:0006950 Not Cancer Driver No 51 0.087 162 19 0.117 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0006950 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0006950 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0006950 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0006950 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0006950 Not Cancer Driver No 26 0.12 54 6 0.111 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0006950 Not Cancer Driver No 229 0.143 1079 153 0.142 2
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0006950 Not Cancer Driver No 39 0.146 18 3 0.167 89
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0006950 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0006950 Census, Compendium Yes 120 0.138 449 53 0.118 6
EPO EPO P01588 Erythropoietin chr7 GO:0006950 Not Cancer Driver No 27 0.14 9 1 0.111 1
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0006950 Not Cancer Driver No 144 0.201 55 6 0.109 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006950 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0006950 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006950 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0006950 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0006950 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0006950 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0006950 Not Cancer Driver No 25 0.063 53 8 0.151 7
ERLIN1 ERLIN1 O75477 Erlin-1 chr10 GO:0006950 Not Cancer Driver No 29 0.083 46 4 0.087 1
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 GO:0006950 Not Cancer Driver No 38 0.112 22 3 0.136 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0006950 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0006950 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0006950 Not Cancer Driver No 48 0.103 32 5 0.156 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0006950 Not Cancer Driver No 55 0.119 297 37 0.125 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0006950 Census Yes 107 0.143 58 7 0.121 12
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0006950 Census, Compendium Yes 120 0.161 284 44 0.155 11
F12 F12 P00748 Coagulation factor XII chr5 GO:0006950 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0006950 Not Cancer Driver No 115 0.185 97 25 0.258 10
F8 F8 P00451 Coagulation factor VIII chrX GO:0006950 Not Cancer Driver No 414 0.176 931 174 0.187 472
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0006950 Not Cancer Driver No 34 0.268 0 0 0.0 0
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0006950 Not Cancer Driver No 37 0.117 54 11 0.204 0
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 GO:0006950 Not Cancer Driver No 78 0.128 169 23 0.136 5
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0006950 Not Cancer Driver No 27 0.117 48 9 0.188 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0006950 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0006950 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0006950 Not Cancer Driver No 268 0.131 898 128 0.143 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0006950 Census, Compendium Yes 55 0.164 62 18 0.29 22
FBXL20 FBXL20 Q96IG2 F-box/LRR-repeat protein 20 chr17 GO:0006950 Not Cancer Driver No 48 0.11 1 0 0.0 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0006950 Not Cancer Driver No 72 0.134 231 30 0.13 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0006950 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0006950 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCMR FCMR O60667 Fas apoptotic inhibitory molecule 3 chr1 GO:0006950 Not Cancer Driver No 55 0.141 229 29 0.127 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0006950 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0006950 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0006950 Not Cancer Driver No 46 0.154 65 19 0.292 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0006950 Not Cancer Driver No 114 0.139 145 21 0.145 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0006950 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0006950 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0006950 Not Cancer Driver No 18 0.062 183 5 0.027 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0006950 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLRT3_ENST00000341420 FLRT3 Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 chr20 GO:0006950 Not Cancer Driver No 108 0.166 112 15 0.134 4
FN1 FN1 P02751 Fibronectin chr2 GO:0006950 Compendium Yes 394 0.159 1243 185 0.149 8
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0006950 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOS FOS P01100 Protein c-Fos chr14 GO:0006950 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0006950 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0006950 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0006950 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0006950 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0006950 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX GO:0006950 Census Yes 75 0.149 441 61 0.138 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0006950 Not Cancer Driver No 16 0.076 73 0 0.0 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0006950 Not Cancer Driver No 92 0.171 70 13 0.186 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0006950 Not Cancer Driver No 9 0.077 11 0 0.0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 GO:0006950 Not Cancer Driver No 19 0.162 10 1 0.1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 GO:0006950 Not Cancer Driver No 11 0.094 2 1 0.5 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0006950 Not Cancer Driver No 146 0.316 55 14 0.255 3
GAL GAL P22466 Galanin peptides chr11 GO:0006950 Not Cancer Driver No 17 0.138 36 2 0.056 1
GALP GALP Q9UBC7 Galanin-like peptide chr19 GO:0006950 Not Cancer Driver No 35 0.302 41 15 0.366 0
GAP43_ENST00000305124 GAP43 P17677 Neuromodulin chr3 GO:0006950 Not Cancer Driver No 79 0.332 238 79 0.332 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0006950 Not Cancer Driver No 39 0.116 24 3 0.125 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0006950 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0006950 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0006950 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 GO:0006950 Not Cancer Driver No 75 0.127 134 15 0.112 0
GBP4 GBP4 Q96PP9 Guanylate-binding protein 4 chr1 GO:0006950 Not Cancer Driver No 114 0.178 165 31 0.188 0
GBP6 GBP6 Q6ZN66 Guanylate-binding protein 6 chr1 GO:0006950 Not Cancer Driver No 112 0.177 157 21 0.134 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0006950 Not Cancer Driver No 88 0.138 93 8 0.086 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0006950 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0006950 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0006950 Not Cancer Driver No 32 0.117 31 3 0.097 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0006950 Not Cancer Driver No 327 0.122 117 16 0.137 0
GCNA GCNA Q96QF7 Germ cell nuclear acidic protein chrX GO:0006950 Not Cancer Driver No 155 0.224 513 122 0.238 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0006950 Not Cancer Driver No 65 0.15 288 42 0.146 62
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0006950 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0006950 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0006950 Not Cancer Driver No 45 0.097 41 0 0.0 0
GJA4 GJA4 P35212 Gap junction alpha-4 protein chr1 GO:0006950 Not Cancer Driver No 48 0.144 74 14 0.189 0
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0006950 Not Cancer Driver No 34 0.15 0 0 0.0 46
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0006950 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0006950 Not Cancer Driver No 12 0.073 10 1 0.1 0
GML GML Q99445 Glycosyl-phosphatidylinositol-anchored molecule-like protein chr8 GO:0006950 Not Cancer Driver No 49 0.31 12 6 0.5 0
GNLY_ENST00000263863 GNLY P22749 Granulysin chr2 GO:0006950 Not Cancer Driver No 28 0.193 19 1 0.053 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0006950 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPR151 GPR151 Q8TDV0 G-protein coupled receptor 151 chr5 GO:0006950 Not Cancer Driver No 51 0.122 97 13 0.134 0
GPR31 GPR31 O00270 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor chr6 GO:0006950 Not Cancer Driver No 52 0.163 14 3 0.214 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0006950 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0006950 Not Cancer Driver No 38 0.187 12 1 0.083 0
GPX3_ENST00000622181 GPX3 P22352 Glutathione peroxidase 3 chr5 GO:0006950 Not Cancer Driver No 29 0.128 7 0 0.0 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0006950 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0006950 Not Cancer Driver No 316 0.345 91 31 0.341 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0006950 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0006950 Not Cancer Driver No 32 0.152 0 0 0.0 0
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 GO:0006950 Not Cancer Driver No 91 0.126 660 85 0.129 0
GZMB GZMB P10144 Granzyme B chr14 GO:0006950 Not Cancer Driver No 49 0.198 103 23 0.223 0
H2AFX H2AX P16104 Histone H2AX chr11 GO:0006950 Not Cancer Driver No 20 0.14 68 10 0.147 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 GO:0006950 Not Cancer Driver No 1 0.008 86 1 0.012 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0006950 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0006950 Not Cancer Driver No 100 0.181 17 7 0.412 0
HBA2 HBA2 P69905 Hemoglobin subunit alpha chr16 GO:0006950 Not Cancer Driver No 9 0.063 4 0 0.0 0
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0006950 Not Cancer Driver No 45 0.306 7 2 0.286 5
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0006950 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0006950 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0006950 Not Cancer Driver No 182 0.168 749 132 0.176 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0006950 Not Cancer Driver No 178 0.147 409 59 0.144 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0006950 Not Cancer Driver No 64 0.19 179 26 0.145 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0006950 Not Cancer Driver No 55 0.158 27 2 0.074 11
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0006950 Not Cancer Driver No 37 0.106 77 9 0.117 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0006950 Census Yes 118 0.143 435 51 0.117 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0006950 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIST1H2BC H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006950 Not Cancer Driver No 53 0.421 79 27 0.342 0
HIST1H2BE H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006950 Not Cancer Driver No 26 0.206 79 16 0.203 0
HIST1H2BF H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006950 Not Cancer Driver No 30 0.238 79 20 0.253 0
HIST1H2BG H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006950 Not Cancer Driver No 45 0.357 79 25 0.316 0
HIST1H2BI H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006950 Not Cancer Driver No 30 0.238 79 18 0.228 0
HIST1H2BJ_ENST00000339812 H2BC11 P06899 Histone H2B type 1-J chr6 GO:0006950 Not Cancer Driver No 22 0.175 75 13 0.173 0
HIST1H2BK H2BC12 O60814 Histone H2B type 1-K chr6 GO:0006950 Not Cancer Driver No 42 0.333 78 29 0.372 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 GO:0006950 Not Cancer Driver No 47 0.373 77 30 0.39 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 GO:0006950 Not Cancer Driver No 21 0.162 61 10 0.164 0
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0006950 Not Cancer Driver No 138 0.15 77 7 0.091 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0006950 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0006950 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0006950 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 GO:0006950 Census Yes 6 0.056 107 6 0.056 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0006950 Census Yes 12 0.11 109 12 0.11 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0006950 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0006950 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0006950 Not Cancer Driver No 92 0.181 29 4 0.138 19
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0006950 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0006950 Not Cancer Driver No 70 0.188 290 58 0.2 4
HP HP P00738 Haptoglobin chr16 GO:0006950 Not Cancer Driver No 39 0.096 57 2 0.035 1
HPR HPR P00739 Haptoglobin-related protein chr16 GO:0006950 Not Cancer Driver No 58 0.167 22 4 0.182 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0006950 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0006950 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSBP1L1 HSBP1L1 C9JCN9 Heat shock factor-binding protein 1-like protein 1 chr18 GO:0006950 Not Cancer Driver No 6 0.081 66 5 0.076 0
HSBP1_ENST00000570259 HSBP1 O75506 Heat shock factor-binding protein 1 chr16 GO:0006950 Not Cancer Driver No 6 0.079 76 6 0.079 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0006950 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 GO:0006950 Not Cancer Driver No 52 0.156 23 3 0.13 1
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0006950 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0006950 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0006950 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0006950 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 GO:0006950 Not Cancer Driver No 112 0.174 235 27 0.115 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0006950 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 GO:0006950 Not Cancer Driver No 170 0.403 100 49 0.49 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0006950 Not Cancer Driver No 140 0.306 40 11 0.275 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0006950 Compendium Yes 44 0.096 127 9 0.071 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0006950 Not Cancer Driver No 669 0.153 2091 329 0.157 21
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0006950 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0006950 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0006950 Not Cancer Driver No 132 0.132 373 47 0.126 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0006950 Not Cancer Driver No 25 0.083 30 2 0.067 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0006950 Not Cancer Driver No 14 0.104 52 7 0.135 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0006950 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0006950 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0006950 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0006950 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0006950 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0006950 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0006950 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0006950 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0006950 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0006950 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0006950 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1F10_ENST00000341010 IL1F10 Q8WWZ1 Interleukin-1 family member 10 chr2 GO:0006950 Not Cancer Driver No 30 0.197 10 1 0.1 0
IL1RL2 IL1RL2 Q9HB29 Interleukin-1 receptor-like 2 chr2 GO:0006950 Not Cancer Driver No 114 0.198 11 4 0.364 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0006950 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0006950 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL22_ENST00000328087 IL22 Q9GZX6 Interleukin-22 chr12 GO:0006950 Not Cancer Driver No 32 0.179 0 0 0.0 0
IL25 IL25 Q9H293 Interleukin-25 chr14 GO:0006950 Not Cancer Driver No 30 0.169 50 8 0.16 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0006950 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0006950 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 GO:0006950 Not Cancer Driver No 44 0.278 13 3 0.231 0
IL36B IL36B Q9NZH7 Interleukin-36 beta chr2 GO:0006950 Not Cancer Driver No 53 0.323 32 8 0.25 0
IL36G IL36G Q9NZH8 Interleukin-36 gamma chr2 GO:0006950 Not Cancer Driver No 35 0.207 23 5 0.217 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0006950 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL37 IL37 Q9NZH6 Interleukin-37 chr2 GO:0006950 Not Cancer Driver No 56 0.257 71 13 0.183 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0006950 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0006950 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 GO:0006950 Not Cancer Driver No 92 0.219 23 5 0.217 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0006950 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0006950 Not Cancer Driver No 55 0.118 165 23 0.139 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0006950 Not Cancer Driver No 49 0.153 84 12 0.143 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0006950 Not Cancer Driver No 31 0.124 108 15 0.139 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0006950 Compendium Yes 173 0.111 682 76 0.111 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0006950 Not Cancer Driver No 138 0.122 394 45 0.114 0
INS INS P01308 Insulin chr11 GO:0006950 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0006950 Not Cancer Driver No 37 0.134 43 1 0.023 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 GO:0006950 Not Cancer Driver No 47 0.209 11 3 0.273 0
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0006950 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0006950 Not Cancer Driver No 80 0.188 77 20 0.26 2
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0006950 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0006950 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0006950 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0006950 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITIH4 ITIH4 Q14624 Inter-alpha-trypsin inhibitor heavy chain H4 chr3 GO:0006950 Not Cancer Driver No 103 0.111 264 39 0.148 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0006950 Census Yes 139 0.224 43 10 0.233 1
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0006950 Not Cancer Driver No 390 0.141 581 76 0.131 6
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0006950 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUN JUN P05412 Transcription factor Jun chr1 GO:0006950 Census Yes 35 0.106 281 25 0.089 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0006950 Not Cancer Driver No 65 0.127 173 21 0.121 3
KAT6A_ENST00000406337 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 GO:0006950 Census, Compendium Yes 273 0.136 1420 193 0.136 0
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0006950 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0006950 Not Cancer Driver No 109 0.256 40 10 0.25 0
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0006950 Not Cancer Driver No 122 0.115 337 44 0.131 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:0006950 Not Cancer Driver No 189 0.115 1278 142 0.111 2
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0006950 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0006950 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIR3DL1 KIR3DL1 P43629 Killer cell immunoglobulin-like receptor 3DL1 chr19 GO:0006950 Not Cancer Driver No 124 0.279 184 48 0.261 0
KIR3DL2 KIR3DL2 P43630 Killer cell immunoglobulin-like receptor 3DL2 chr19 GO:0006950 Not Cancer Driver No 91 0.2 118 31 0.263 0
KL KL Q9UEF7 Klotho chr13 GO:0006950 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 GO:0006950 Not Cancer Driver No 66 0.159 273 48 0.176 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0006950 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0006950 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0006950 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0006950 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRG1_ENST00000266551 KLRG1 Q96E93 Killer cell lectin-like receptor subfamily G member 1 chr12 GO:0006950 Not Cancer Driver No 24 0.123 8 1 0.125 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0006950 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0006950 Not Cancer Driver No 77 0.158 0 0 0.0 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:0006950 Not Cancer Driver No 44 0.101 21 2 0.095 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0006950 Not Cancer Driver No 133 0.207 426 98 0.23 20
KRT6A KRT6A P02538 Keratin, type II cytoskeletal 6A chr12 GO:0006950 Not Cancer Driver No 127 0.225 138 35 0.254 24
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0006950 Not Cancer Driver No 46 0.176 16 6 0.375 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0006950 Not Cancer Driver No 133 0.113 97 10 0.103 1
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0006950 Not Cancer Driver No 84 0.175 6 0 0.0 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0006950 Not Cancer Driver No 119 0.138 63 3 0.048 104
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 GO:0006950 Not Cancer Driver No 62 0.106 9 0 0.0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0006950 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0006950 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0006950 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0006950 Not Cancer Driver No 148 0.248 235 50 0.213 0
LRP11 LRP11 Q86VZ4 Low-density lipoprotein receptor-related protein 11 chr6 GO:0006950 Not Cancer Driver No 36 0.072 254 20 0.079 0
LSP1_ENST00000311604 LSP1 P33241 Lymphocyte-specific protein 1 chr11 GO:0006950 Not Cancer Driver No 44 0.13 337 43 0.128 0
LTF LTF P02788 Lactotransferrin chr3 GO:0006950 Not Cancer Driver No 131 0.185 21 4 0.19 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0006950 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0006950 Census Yes 95 0.186 84 12 0.143 0
LYPD1 LYPD1 Q8N2G4 Ly6/PLAUR domain-containing protein 1 chr2 GO:0006950 Not Cancer Driver No 20 0.142 5 0 0.0 0
LYST LYST Q99698 Lysosomal-trafficking regulator chr1 GO:0006950 Not Cancer Driver No 465 0.122 608 87 0.143 4
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0006950 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0006950 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0006950 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 GO:0006950 Not Cancer Driver No 22 0.182 24 1 0.042 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 GO:0006950 Not Cancer Driver No 10 0.08 17 1 0.059 0
MAP1LC3B2 MAP1LC3B2 A6NCE7 Microtubule-associated proteins 1A/1B light chain 3 beta 2 chr12 GO:0006950 Not Cancer Driver No 19 0.152 17 7 0.412 0
MAP1LC3C MAP1LC3C Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C chr1 GO:0006950 Not Cancer Driver No 32 0.218 31 5 0.161 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0006950 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0006950 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0006950 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0006950 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0006950 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0006950 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0006950 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0006950 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0006950 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 GO:0006950 Not Cancer Driver No 88 0.19 107 16 0.15 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0006950 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0006950 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0006950 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0006950 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0006950 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0006950 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0006950 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0006950 Not Cancer Driver No 49 0.059 568 27 0.048 0
MAPK8IP3_ENST00000250894 MAPK8IP3 Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 chr16 GO:0006950 Not Cancer Driver No 179 0.134 746 110 0.147 3
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0006950 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0006950 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0006950 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0006950 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0006950 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0006950 Not Cancer Driver No 33 0.134 23 5 0.217 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0006950 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0006950 Not Cancer Driver No 99 0.144 58 11 0.19 2
MAX MAX P61244 Protein max chr14 GO:0006950 Census, Compendium Yes 45 0.281 160 45 0.281 9
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0006950 Not Cancer Driver No 63 0.254 122 32 0.262 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 GO:0006950 Not Cancer Driver No 140 0.133 206 36 0.175 1
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0006950 Not Cancer Driver No 63 0.121 16 4 0.25 9
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0006950 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0006950 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0006950 Not Cancer Driver No 56 0.049 523 13 0.025 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0006950 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0006950 Census, Compendium Yes 56 0.114 297 37 0.125 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 GO:0006950 Census, Compendium Yes 57 0.116 202 26 0.129 1
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0006950 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0006950 Not Cancer Driver No 92 0.195 408 81 0.199 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0006950 Not Cancer Driver No 35 0.137 0 0 0.0 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0006950 Not Cancer Driver No 80 0.106 81 9 0.111 20
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0006950 Not Cancer Driver No 33 0.096 95 7 0.074 1
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 GO:0006950 Not Cancer Driver No 26 0.168 0 0 0.0 0
MID2 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX GO:0006950 Not Cancer Driver No 112 0.152 95 24 0.253 1
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0006950 Not Cancer Driver No 4 0.035 0 0 0.0 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0006950 Not Cancer Driver No 41 0.083 82 0 0.0 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0006950 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0006950 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0006950 Not Cancer Driver No 180 0.442 172 76 0.442 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0006950 Not Cancer Driver No 300 0.305 252 77 0.306 0
MORN4 MORN4 Q8NDC4 MORN repeat-containing protein 4 chr10 GO:0006950 Not Cancer Driver No 18 0.123 15 0 0.0 0
MPV17 MPV17 P39210 Protein Mpv17 chr2 GO:0006950 Not Cancer Driver No 21 0.119 0 0 0.0 16
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0006950 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRGPRX1 MRGPRX1 Q96LB2 Mas-related G-protein coupled receptor member X1 chr11 GO:0006950 Not Cancer Driver No 123 0.382 0 0 0.0 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0006950 Census Yes 154 0.113 386 41 0.106 6
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0006950 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0006950 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0006950 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTR MTR Q99707 Methionine synthase chr1 GO:0006950 Not Cancer Driver No 151 0.119 104 17 0.163 2
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0006950 Not Cancer Driver No 107 0.142 584 86 0.147 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0006950 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0006950 Not Cancer Driver No 48 0.136 16 2 0.125 0
MX1_ENST00000398598 MX1 P20591 Interferon-induced GTP-binding protein Mx1 chr21 GO:0006950 Not Cancer Driver No 88 0.133 74 10 0.135 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0006950 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0006950 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0006950 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYH6 MYH6 P13533 Myosin-6 chr14 GO:0006950 Not Cancer Driver No 392 0.202 1112 238 0.214 7
MYH7 MYH7 P12883 Myosin-7 chr14 GO:0006950 Not Cancer Driver No 464 0.24 1107 276 0.249 200
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0006950 Not Cancer Driver No 343 0.179 957 184 0.192 3
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0006950 Not Cancer Driver No 176 0.136 342 41 0.12 3
NBN NBN O60934 Nibrin chr8 GO:0006950 Census Yes 90 0.119 417 54 0.129 1
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0006950 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0006950 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0006950 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0006950 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0006950 Not Cancer Driver No 81 0.266 27 8 0.296 0
NCR2 NCR2 O95944 Natural cytotoxicity triggering receptor 2 chr6 GO:0006950 Not Cancer Driver No 63 0.228 60 14 0.233 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0006950 Not Cancer Driver No 125 0.22 129 29 0.225 1
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0006950 Census Yes 66 0.168 140 22 0.157 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0006950 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0006950 Not Cancer Driver No 92 0.169 285 39 0.137 12
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0006950 Not Cancer Driver No 60 0.101 294 37 0.126 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0006950 Not Cancer Driver No 26 0.068 210 14 0.067 2
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0006950 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0006950 Compendium Yes 37 0.117 102 9 0.088 1
NGLY1 NGLY1 Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase chr3 GO:0006950 Not Cancer Driver No 79 0.121 98 13 0.133 0
NIM1K NIM1K Q8IY84 Serine/threonine-protein kinase NIM1 chr5 GO:0006950 Not Cancer Driver No 73 0.167 126 21 0.167 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0006950 Compendium Yes 353 0.126 1528 184 0.12 37
NKG7 NKG7 Q16617 Protein NKG7 chr19 GO:0006950 Not Cancer Driver No 34 0.206 0 0 0.0 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0006950 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0006950 Not Cancer Driver No 106 0.119 203 28 0.138 0
NME8_ENST00000440017 NME8 Q8N427 Thioredoxin domain-containing protein 3 chr7 GO:0006950 Not Cancer Driver No 178 0.303 87 44 0.506 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0006950 Not Cancer Driver No 139 0.335 5 1 0.2 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0006950 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0006950 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0006950 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0006950 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0006950 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0006950 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0006950 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0006950 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPC1L1 NPC1L1 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 chr7 GO:0006950 Not Cancer Driver No 222 0.163 8 2 0.25 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0006950 Not Cancer Driver No 32 0.212 71 14 0.197 1
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0006950 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR0B1 NR0B1 P51843 Nuclear receptor subfamily 0 group B member 1 chrX GO:0006950 Not Cancer Driver No 106 0.226 97 18 0.186 18
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0006950 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0006950 Not Cancer Driver No 110 0.184 261 38 0.146 0
NREP_ENST00000447165 NREP Q16612 Neuronal regeneration-related protein chr5 GO:0006950 Not Cancer Driver No 17 0.25 36 13 0.361 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0006950 Not Cancer Driver No 30 0.121 119 12 0.101 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0006950 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0006950 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0006950 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0006950 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0006950 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0006950 Not Cancer Driver No 10 0.122 82 10 0.122 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0006950 Not Cancer Driver No 67 0.168 71 12 0.169 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006950 Not Cancer Driver No 37 0.107 71 12 0.169 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 GO:0006950 Not Cancer Driver No 52 0.099 34 4 0.118 0
OMG OMG P23515 Oligodendrocyte-myelin glycoprotein chr17 GO:0006950 Not Cancer Driver No 38 0.086 122 10 0.082 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0006950 Not Cancer Driver No 114 0.119 131 17 0.13 60
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0006950 Not Cancer Driver No 107 0.268 58 27 0.466 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0006950 Not Cancer Driver No 58 0.101 470 51 0.109 6
ORM1 ORM1 P02763 Alpha-1-acid glycoprotein 1 chr9 GO:0006950 Not Cancer Driver No 38 0.189 23 2 0.087 0
ORM2 ORM2 P19652 Alpha-1-acid glycoprotein 2 chr9 GO:0006950 Not Cancer Driver No 38 0.189 22 2 0.091 0
OSER1 OSER1 Q9NX31 Oxidative stress-responsive serine-rich protein 1 chr20 GO:0006950 Not Cancer Driver No 32 0.11 221 28 0.127 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0006950 Not Cancer Driver No 126 0.144 544 76 0.14 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0006950 Not Cancer Driver No 69 0.131 208 29 0.139 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0006950 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0006950 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0006950 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0006950 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0006950 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0006950 Not Cancer Driver No 57 0.167 21 2 0.095 3
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0006950 Not Cancer Driver No 54 0.127 45 7 0.156 2
PANX2 PANX2 Q96RD6 Pannexin-2 chr22 GO:0006950 Not Cancer Driver No 73 0.108 293 14 0.048 0
PAPPA2 PAPPA2 Q9BXP8 Pappalysin-2 chr1 GO:0006950 Not Cancer Driver No 739 0.413 370 141 0.381 1
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006950 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0006950 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0006950 Not Cancer Driver No 37 0.115 33 3 0.091 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0006950 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0006950 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0006950 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0006950 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0006950 Not Cancer Driver No 139 0.185 336 61 0.182 2
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0006950 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0006950 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0006950 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0006950 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0006950 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0006950 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0006950 Not Cancer Driver No 37 0.228 96 24 0.25 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0006950 Not Cancer Driver No 109 0.408 142 62 0.437 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0006950 Not Cancer Driver No 166 0.132 782 101 0.129 1
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0006950 Not Cancer Driver No 13 0.129 0 0 0.0 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0006950 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0006950 Not Cancer Driver No 37 0.136 4 1 0.25 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0006950 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0006950 Not Cancer Driver No 93 0.102 137 14 0.102 0
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0006950 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0006950 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0006950 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0006950 Not Cancer Driver No 193 0.142 315 45 0.143 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0006950 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:0006950 Not Cancer Driver No 36 0.13 78 4 0.051 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0006950 Not Cancer Driver No 24 0.079 155 12 0.077 1
PJVK_ENST00000644580 PJVK Q0ZLH3 Pejvakin chr2 GO:0006950 Not Cancer Driver No 48 0.136 1 0 0.0 3
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0006950 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0006950 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0006950 Not Cancer Driver No 120 0.127 459 54 0.118 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0006950 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0006950 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0006950 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEC PLEC Q15149 Plectin chr8 GO:0006950 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0006950 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLEKHM2 PLEKHM2 Q8IWE5 Pleckstrin homology domain-containing family M member 2 chr1 GO:0006950 Not Cancer Driver No 96 0.094 392 35 0.089 0
PLIN1_ENST00000430628 PLIN1 O60240 Perilipin-1 chr15 GO:0006950 Not Cancer Driver No 43 0.082 304 20 0.066 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0006950 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0006950 Not Cancer Driver No 75 0.116 202 15 0.074 0
PLK5 PLK5 Q496M5 Inactive serine/threonine-protein kinase PLK5 chr19 GO:0006950 Not Cancer Driver No 8 0.024 215 4 0.019 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0006950 Not Cancer Driver No 43 0.135 92 13 0.141 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0006950 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0006950 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNLIPRP2 PNLIPRP2 P54317 Pancreatic lipase-related protein 2 chr10 GO:0006950 Not Cancer Driver No 75 0.16 28 2 0.071 0
PNMA1 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 GO:0006950 Not Cancer Driver No 48 0.136 56 9 0.161 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0006950 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0006950 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:0006950 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:0006950 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0006950 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0006950 Census, Compendium Yes 409 0.179 239 44 0.184 3
POLE2 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0006950 Not Cancer Driver No 53 0.101 32 2 0.062 0
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0006950 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLI POLI Q9UNA4 DNA polymerase iota chr18 GO:0006950 Not Cancer Driver No 82 0.111 300 32 0.107 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0006950 Not Cancer Driver No 97 0.111 293 36 0.123 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0006950 Census, Compendium Yes 364 0.141 949 135 0.142 0
POLR2D POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 GO:0006950 Not Cancer Driver No 13 0.092 54 2 0.037 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 GO:0006950 Not Cancer Driver No 21 0.168 22 5 0.227 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0006950 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0006950 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0006950 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0006950 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0006950 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0006950 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0006950 Not Cancer Driver No 37 0.12 12 0 0.0 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0006950 Compendium Yes 85 0.163 140 27 0.193 7
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0006950 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 GO:0006950 Not Cancer Driver No 58 0.117 0 0 0.0 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0006950 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0006950 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0006950 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0006950 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0006950 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0006950 Census, Compendium Yes 122 0.22 145 36 0.248 8
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0006950 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0006950 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0006950 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0006950 Census Yes 53 0.151 24 0 0.0 2
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0006950 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0006950 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 GO:0006950 Not Cancer Driver No 74 0.151 144 25 0.174 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0006950 Compendium Yes 79 0.117 43 9 0.209 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0006950 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0006950 Census Yes 201 0.22 189 33 0.175 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0006950 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0006950 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 GO:0006950 Not Cancer Driver No 43 0.115 71 7 0.099 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0006950 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0006950 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0006950 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTN PTN P21246 Pleiotrophin chr7 GO:0006950 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0006950 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0006950 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 GO:0006950 Not Cancer Driver No 268 0.141 696 96 0.138 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0006950 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0006950 Not Cancer Driver No 142 0.145 498 73 0.147 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0006950 Not Cancer Driver No 62 0.105 341 24 0.07 0
QRICH1_ENST00000357496 QRICH1 Q2TAL8 Transcriptional regulator QRICH1 chr3 GO:0006950 Not Cancer Driver No 93 0.12 423 55 0.13 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0006950 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0006950 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:0006950 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0006950 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0006950 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0006950 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAET1E RAET1E Q8TD07 Retinoic acid early transcript 1E chr6 GO:0006950 Not Cancer Driver No 40 0.152 0 0 0.0 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0006950 Not Cancer Driver No 41 0.123 62 10 0.161 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0006950 Not Cancer Driver No 65 0.111 159 17 0.107 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0006950 Not Cancer Driver No 16 0.098 14 2 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0006950 Not Cancer Driver No 96 0.12 191 12 0.063 1
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX GO:0006950 Not Cancer Driver No 67 0.158 138 19 0.138 0
RBMS3 RBMS3 Q6XE24 RNA-binding motif, single-stranded-interacting protein 3 chr3 GO:0006950 Not Cancer Driver No 87 0.199 278 57 0.205 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0006950 Not Cancer Driver No 49 0.098 151 19 0.126 2
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0006950 Not Cancer Driver No 10 0.093 18 1 0.056 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:0006950 Not Cancer Driver No 26 0.103 104 7 0.067 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0006950 Not Cancer Driver No 33 0.126 23 0 0.0 0
RCSD1 RCSD1 Q6JBY9 CapZ-interacting protein chr1 GO:0006950 Not Cancer Driver No 70 0.168 416 70 0.168 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0006950 Not Cancer Driver No 60 0.11 244 26 0.107 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0006950 Not Cancer Driver No 132 0.133 495 71 0.143 0
REG3A_ENST00000305165 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0006950 Not Cancer Driver No 93 0.531 19 10 0.526 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0006950 Not Cancer Driver No 81 0.463 17 4 0.235 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0006950 Compendium Yes 75 0.136 400 48 0.12 0
RELN RELN P78509 Reelin chr7 GO:0006950 Not Cancer Driver No 761 0.22 107 19 0.178 7
REN REN P00797 Renin chr1 GO:0006950 Not Cancer Driver No 60 0.148 10 0 0.0 3
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0006950 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0006950 Census, Compendium Yes 208 0.187 105 12 0.114 139
REV1 REV1 Q9UBZ9 DNA repair protein REV1 chr2 GO:0006950 Not Cancer Driver No 122 0.098 660 67 0.102 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:0006950 Not Cancer Driver No 379 0.121 1665 211 0.127 0
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:0006950 Census Yes 68 0.088 318 30 0.094 1
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0006950 Not Cancer Driver No 57 0.101 309 37 0.12 0
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0006950 Not Cancer Driver No 52 0.265 19 2 0.105 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0006950 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0006950 Compendium Yes 82 0.122 277 39 0.141 4
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0006950 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0006950 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE3 RNASE3 P12724 Eosinophil cationic protein chr14 GO:0006950 Not Cancer Driver No 37 0.231 8 0 0.0 0
RNASE8 RNASE8 Q8TDE3 Ribonuclease 8 chr14 GO:0006950 Not Cancer Driver No 18 0.117 17 2 0.118 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0006950 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0006950 Not Cancer Driver No 86 0.136 168 26 0.155 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0006950 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0006950 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0006950 Not Cancer Driver No 27 0.119 11 3 0.273 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0006950 Not Cancer Driver No 58 0.079 344 24 0.07 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0006950 Not Cancer Driver No 30 0.081 112 7 0.062 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0006950 Not Cancer Driver No 17 0.094 69 3 0.043 0
RNLS RNLS Q5VYX0 Renalase chr10 GO:0006950 Not Cancer Driver No 42 0.123 15 1 0.067 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0006950 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROMO1_ENST00000397416 ROMO1 P60602 Reactive oxygen species modulator 1 chr20 GO:0006950 Not Cancer Driver No 9 0.114 0 0 0.0 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0006950 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0006950 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL39 RPL39 P62891 60S ribosomal protein L39 chrX GO:0006950 Not Cancer Driver No 9 0.176 51 9 0.176 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 GO:0006950 Not Cancer Driver No 4 0.048 22 2 0.091 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0006950 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0006950 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0006950 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0006950 Not Cancer Driver No 180 0.242 136 36 0.265 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0006950 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0006950 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0006950 Not Cancer Driver No 42 0.105 83 5 0.06 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0006950 Not Cancer Driver No 66 0.145 270 44 0.163 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0006950 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTN4RL1 RTN4RL1 Q86UN2 Reticulon-4 receptor-like 1 chr17 GO:0006950 Not Cancer Driver No 56 0.127 142 12 0.085 0
RTN4RL2 RTN4RL2 Q86UN3 Reticulon-4 receptor-like 2 chr11 GO:0006950 Not Cancer Driver No 38 0.09 121 5 0.041 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0006950 Census Yes 39 0.386 28 14 0.5 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0006950 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0006950 Not Cancer Driver No 18 0.158 76 7 0.092 0
SAA1 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0006950 Not Cancer Driver No 23 0.189 25 5 0.2 0
SAA2_ENST00000529528 SAA2 P0DJI9 Serum amyloid A-2 protein chr11 GO:0006950 Not Cancer Driver No 31 0.254 39 12 0.308 0
SAA4 SAA4 P35542 Serum amyloid A-4 protein chr11 GO:0006950 Not Cancer Driver No 19 0.146 28 5 0.179 0
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0006950 Not Cancer Driver No 36 0.05 80 4 0.05 0
SAXO1 SAXO1 Q8IYX7 Stabilizer of axonemal microtubules 1 chr9 GO:0006950 Not Cancer Driver No 63 0.133 249 35 0.141 0
SCAP SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 GO:0006950 Not Cancer Driver No 145 0.113 329 36 0.109 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0006950 Not Cancer Driver No 12 0.132 14 2 0.143 0
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0006950 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0006950 Not Cancer Driver No 90 0.141 62 4 0.065 13
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0006950 Not Cancer Driver No 31 0.1 259 30 0.116 0
SDE2 SDE2 Q6IQ49 Replication stress response regulator SDE2 chr1 GO:0006950 Not Cancer Driver No 56 0.124 290 35 0.121 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 GO:0006950 Not Cancer Driver No 16 0.072 130 9 0.069 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0006950 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0006950 Not Cancer Driver No 7 0.037 122 6 0.049 0
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0006950 Not Cancer Driver No 149 0.142 523 73 0.14 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 GO:0006950 Not Cancer Driver No 66 0.158 38 7 0.184 0
SERPINA3_ENST00000393080 SERPINA3 P01011 Alpha-1-antichymotrypsin chr14 GO:0006950 Not Cancer Driver No 117 0.277 18 10 0.556 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0006950 Not Cancer Driver No 62 0.126 112 21 0.188 1
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0006950 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0006950 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0006950 Not Cancer Driver No 84 0.171 44 4 0.091 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0006950 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0006950 Not Cancer Driver No 66 0.176 274 53 0.193 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX GO:0006950 Not Cancer Driver No 40 0.312 24 8 0.333 19
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0006950 Not Cancer Driver No 41 0.112 82 10 0.122 0
SIGIRR_ENST00000397632 SIGIRR Q6IA17 Single Ig IL-1-related receptor chr11 GO:0006950 Not Cancer Driver No 27 0.066 85 4 0.047 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0006950 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 GO:0006950 Not Cancer Driver No 94 0.102 525 56 0.107 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0006950 Compendium Yes 172 0.135 617 73 0.118 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0006950 Not Cancer Driver No 67 0.064 666 43 0.065 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0006950 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0006950 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0006950 Not Cancer Driver No 56 0.144 85 17 0.2 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 GO:0006950 Not Cancer Driver No 66 0.197 53 14 0.264 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0006950 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0006950 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0006950 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 GO:0006950 Not Cancer Driver No 168 0.146 280 46 0.164 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0006950 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0006950 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0006950 Not Cancer Driver No 51 0.104 13 2 0.154 48
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0006950 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 GO:0006950 Not Cancer Driver No 77 0.119 116 11 0.095 9
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0006950 Not Cancer Driver No 67 0.124 139 18 0.129 1
SLC4A11_ENST00000539553 SLC4A11 Q8NBS3 Solute carrier family 4 member 11 chr20 GO:0006950 Not Cancer Driver No 159 0.182 69 10 0.145 42
SLC6A2_ENST00000568943 SLC6A2 P23975 Sodium-dependent noradrenaline transporter chr16 GO:0006950 Not Cancer Driver No 127 0.206 23 8 0.348 1
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0006950 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0006950 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0006950 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A4 SLC9A4 Q6AI14 Sodium/hydrogen exchanger 4 chr2 GO:0006950 Not Cancer Driver No 197 0.247 197 77 0.391 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0006950 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0006950 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0006950 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0006950 Not Cancer Driver No 128 0.117 458 57 0.124 0
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0006950 Not Cancer Driver No 92 0.14 224 29 0.129 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0006950 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0006950 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0006950 Not Cancer Driver No 32 0.144 25 5 0.2 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0006950 Not Cancer Driver No 96 0.122 599 71 0.119 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0006950 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0006950 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0006950 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0006950 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0006950 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0006950 Not Cancer Driver No 36 0.109 73 4 0.055 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0006950 Not Cancer Driver No 73 0.149 252 38 0.151 1
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0006950 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0006950 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0006950 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0006950 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0006950 Not Cancer Driver No 44 0.087 443 42 0.095 0
SST SST P61278 Somatostatin chr3 GO:0006950 Not Cancer Driver No 25 0.216 40 15 0.375 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0006950 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0006950 Census, Compendium Yes 106 0.125 325 44 0.135 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0006950 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 GO:0006950 Not Cancer Driver No 42 0.099 170 15 0.088 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0006950 Not Cancer Driver No 62 0.149 119 18 0.151 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0006950 Not Cancer Driver No 64 0.117 182 19 0.104 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0006950 Not Cancer Driver No 40 0.112 117 9 0.077 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0006950 Not Cancer Driver No 121 0.122 659 83 0.126 2
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0006950 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0006950 Not Cancer Driver No 59 0.143 15 1 0.067 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0006950 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAC1 TAC1 P20366 Protachykinin-1 chr7 GO:0006950 Not Cancer Driver No 31 0.24 18 4 0.222 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0006950 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 GO:0006950 Not Cancer Driver No 137 0.295 31 17 0.548 5
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 GO:0006950 Not Cancer Driver No 68 0.152 115 13 0.113 0
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0006950 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0006950 Census, Compendium Yes 123 0.166 352 57 0.162 2
TCAP TCAP O15273 Telethonin chr17 GO:0006950 Not Cancer Driver No 16 0.096 94 10 0.106 3
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0006950 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0006950 Compendium Yes 68 0.082 102 6 0.059 5
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0006950 Not Cancer Driver No 81 0.133 179 25 0.14 1
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0006950 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0006950 Not Cancer Driver No 28 0.07 310 16 0.052 0
TEX264_ENST00000416589 TEX264 Q9Y6I9 Testis-expressed protein 264 chr3 GO:0006950 Not Cancer Driver No 40 0.128 107 11 0.103 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0006950 Compendium Yes 61 0.18 285 52 0.182 0
TFF1 TFF1 P04155 Trefoil factor 1 chr21 GO:0006950 Not Cancer Driver No 9 0.107 0 0 0.0 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0006950 Not Cancer Driver No 87 0.104 331 39 0.118 0
TFPI2 TFPI2 P48307 Tissue factor pathway inhibitor 2 chr7 GO:0006950 Not Cancer Driver No 54 0.23 5 11 2.2 0
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0006950 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0006950 Census Yes 89 0.117 80 6 0.075 1
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0006950 Not Cancer Driver No 45 0.109 96 14 0.146 1
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0006950 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0006950 Not Cancer Driver No 188 0.161 320 58 0.181 0
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0006950 Not Cancer Driver No 32 0.107 22 2 0.091 1
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0006950 Not Cancer Driver No 44 0.163 39 9 0.231 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0006950 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0006950 Not Cancer Driver No 292 0.348 0 0 0.0 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0006950 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMCO1 TMCO1 Q9UM00 Calcium load-activated calcium channel chr1 GO:0006950 Not Cancer Driver No 31 0.13 49 5 0.102 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0006950 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM117 TMEM117 Q9H0C3 Transmembrane protein 117 chr12 GO:0006950 Not Cancer Driver No 91 0.177 70 12 0.171 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0006950 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0006950 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0006950 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0006950 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0006950 Not Cancer Driver No 21 0.382 55 21 0.382 0
TOMM7 TOMM7 Q9P0U1 Mitochondrial import receptor subunit TOM7 homolog chr7 GO:0006950 Not Cancer Driver No 7 0.127 0 0 0.0 0
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0006950 Not Cancer Driver No 33 0.099 0 0 0.0 3
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0006950 Not Cancer Driver No 32 0.133 134 20 0.149 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0006950 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0006950 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0006950 Census Yes 311 0.132 1990 266 0.134 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0006950 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0006950 Not Cancer Driver No 63 0.134 240 33 0.138 1
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0006950 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0006950 Not Cancer Driver No 45 0.192 63 7 0.111 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0006950 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006950 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0006950 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0006950 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM11 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 GO:0006950 Not Cancer Driver No 58 0.124 132 14 0.106 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0006950 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0006950 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0006950 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0006950 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 GO:0006950 Not Cancer Driver No 67 0.124 153 16 0.105 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0006950 Census Yes 59 0.115 87 11 0.126 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0006950 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0006950 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 GO:0006950 Not Cancer Driver No 66 0.134 69 9 0.13 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0006950 Not Cancer Driver No 71 0.144 77 11 0.143 0
TRIM8 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 GO:0006950 Not Cancer Driver No 60 0.109 209 29 0.139 0
TRPA1 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0006950 Not Cancer Driver No 324 0.29 62 14 0.226 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0006950 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0006950 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0006950 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSPAN32 TSPAN32 Q96QS1 Tetraspanin-32 chr11 GO:0006950 Not Cancer Driver No 33 0.103 8 3 0.375 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0006950 Not Cancer Driver No 5 0.03 1 0 0.0 0
TUBB TUBB P07437 Tubulin beta chain chr6 GO:0006950 Not Cancer Driver No 40 0.09 63 11 0.175 5
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 GO:0006950 Not Cancer Driver No 52 0.117 65 11 0.169 2
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0006950 Not Cancer Driver No 10 0.091 31 3 0.097 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 GO:0006950 Not Cancer Driver No 22 0.133 34 4 0.118 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0006950 Not Cancer Driver No 61 0.156 77 14 0.182 0
TXNRD2 TXNRD2 Q9NNW7 Thioredoxin reductase 2, mitochondrial chr22 GO:0006950 Not Cancer Driver No 70 0.134 46 6 0.13 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0006950 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0006950 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0006950 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0006950 Not Cancer Driver No 33 0.148 34 7 0.206 4
UCN UCN P55089 Urocortin chr2 GO:0006950 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0006950 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0006950 Not Cancer Driver No 43 0.14 1 0 0.0 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0006950 Not Cancer Driver No 31 0.1 11 3 0.273 0
UCP3 UCP3 P55916 Mitochondrial uncoupling protein 3 chr11 GO:0006950 Not Cancer Driver No 37 0.119 7 1 0.143 1
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0006950 Not Cancer Driver No 26 0.085 100 7 0.07 0
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 GO:0006950 Not Cancer Driver No 169 0.109 161 20 0.124 0
UGGT2 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 GO:0006950 Not Cancer Driver No 190 0.125 64 6 0.094 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0006950 Not Cancer Driver No 100 0.188 11 2 0.182 55
ULBP1 ULBP1 Q9BZM6 UL16-binding protein 1 chr6 GO:0006950 Not Cancer Driver No 48 0.197 24 4 0.167 0
ULBP2 ULBP2 Q9BZM5 UL16-binding protein 2 chr6 GO:0006950 Not Cancer Driver No 33 0.134 25 2 0.08 0
ULBP3 ULBP3 Q9BZM4 UL16-binding protein 3 chr6 GO:0006950 Not Cancer Driver No 34 0.139 14 1 0.071 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0006950 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 GO:0006950 Not Cancer Driver No 37 0.078 55 2 0.036 0
UMOD_ENST00000302509 UMOD P07911 Uromodulin chr16 GO:0006950 Not Cancer Driver No 125 0.195 12 1 0.083 37
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0006950 Not Cancer Driver No 47 0.152 13 3 0.231 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 GO:0006950 Not Cancer Driver No 92 0.115 425 49 0.115 0
USP45 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0006950 Not Cancer Driver No 96 0.118 275 28 0.102 0
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 GO:0006950 Not Cancer Driver No 48 0.131 28 4 0.143 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0006950 Not Cancer Driver No 170 0.154 215 45 0.209 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0006950 Not Cancer Driver No 89 0.127 243 28 0.115 0
UVSSA UVSSA Q2YD98 UV-stimulated scaffold protein A chr4 GO:0006950 Not Cancer Driver No 101 0.142 519 70 0.135 1
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 GO:0006950 Not Cancer Driver No 16 0.066 138 8 0.058 3
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0006950 Not Cancer Driver No 188 0.254 110 28 0.255 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0006950 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0006950 Not Cancer Driver No 133 0.109 543 61 0.112 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0006950 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEZF1 VEZF1 Q14119 Vascular endothelial zinc finger 1 chr17 GO:0006950 Not Cancer Driver No 56 0.107 332 32 0.096 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0006950 Census, Compendium Yes 142 0.667 117 36 0.308 133
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0006950 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0006950 Not Cancer Driver No 73 0.183 70 13 0.186 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0006950 Not Cancer Driver No 106 0.164 571 95 0.166 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 GO:0006950 Not Cancer Driver No 28 0.089 35 3 0.086 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0006950 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0006950 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0006950 Not Cancer Driver No 59 0.162 28 9 0.321 0
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 GO:0006950 Not Cancer Driver No 128 0.15 127 17 0.134 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0006950 Not Cancer Driver No 19 0.073 169 9 0.053 0
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0006950 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0006950 Census, Compendium Yes 88 0.094 479 48 0.1 2
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 GO:0006950 Not Cancer Driver No 103 0.148 70 15 0.214 4
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0006950 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0006950 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0006950 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0006950 Not Cancer Driver No 66 0.108 140 12 0.086 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0006950 Not Cancer Driver No 49 0.132 359 47 0.131 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0006950 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0006950 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZDHHC1 ZDHHC1 Q8WTX9 Palmitoyltransferase ZDHHC1 chr16 GO:0006950 Not Cancer Driver No 46 0.095 167 11 0.066 0
ZDHHC11 ZDHHC11 Q9H8X9 Palmitoyltransferase ZDHHC11 chr5 GO:0006950 Not Cancer Driver No 68 0.165 76 24 0.316 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0006950 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0006950 Compendium Yes 57 0.169 212 30 0.142 0
ZG16 ZG16 O60844 Zymogen granule membrane protein 16 chr16 GO:0006950 Not Cancer Driver No 5 0.03 7 1 0.143 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 GO:0006950 Compendium Yes 125 0.157 600 88 0.147 0
ZNF277 ZNF277 Q9NRM2 Zinc finger protein 277 chr7 GO:0006950 Not Cancer Driver No 59 0.131 79 15 0.19 0
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0006950 Not Cancer Driver No 8 0.047 153 8 0.052 0