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Total number of protein in "GO:0001817" GO term:  669

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0001817 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0001817 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0001817 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0001817 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0001817 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACKR1_ENST00000368122 ACKR1 Q16570 Atypical chemokine receptor 1 chr1 GO:0001817 Not Cancer Driver No 94 0.28 0 0 0.0 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0001817 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0001817 Not Cancer Driver No 51 0.157 31 6 0.194 8
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0001817 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0001817 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0001817 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCYAP1_ENST00000450565 ADCYAP1 P18509 Pituitary adenylate cyclase-activating polypeptide chr18 GO:0001817 Not Cancer Driver No 43 0.244 75 11 0.147 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0001817 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0001817 Not Cancer Driver No 23 0.069 0 0 0.0 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0001817 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0001817 Not Cancer Driver No 31 0.077 297 21 0.071 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0001817 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0001817 Not Cancer Driver No 73 0.213 78 22 0.282 0
AIRE AIRE O43918 Autoimmune regulator chr21 GO:0001817 Not Cancer Driver No 71 0.13 338 48 0.142 19
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0001817 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0001817 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKIRIN2 AKIRIN2 Q53H80 Akirin-2 chr6 GO:0001817 Not Cancer Driver No 21 0.103 119 11 0.092 0
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0001817 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0001817 Not Cancer Driver No 129 0.191 16 2 0.125 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0001817 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0001817 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA4 ANXA4 P09525 Annexin A4 chr2 GO:0001817 Not Cancer Driver No 47 0.147 41 6 0.146 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0001817 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0001817 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0001817 Not Cancer Driver No 34 0.18 13 2 0.154 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0001817 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0001817 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0001817 Not Cancer Driver No 70 0.105 149 14 0.094 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0001817 Not Cancer Driver No 50 0.155 30 9 0.3 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 GO:0001817 Not Cancer Driver No 254 0.142 358 63 0.176 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0001817 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0001817 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0001817 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0001817 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0001817 Census Yes 77 0.098 511 56 0.11 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0001817 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0001817 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASB1 ASB1 Q9Y576 Ankyrin repeat and SOCS box protein 1 chr2 GO:0001817 Not Cancer Driver No 49 0.146 37 2 0.054 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0001817 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0001817 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0001817 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0001817 Not Cancer Driver No 56 0.16 0 0 0.0 2
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0001817 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0001817 Not Cancer Driver No 42 0.167 53 13 0.245 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0001817 Census, Compendium Yes 34 0.286 5 1 0.2 2
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0001817 Not Cancer Driver No 10 0.112 11 2 0.182 1
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0001817 Not Cancer Driver No 150 0.191 394 73 0.185 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 GO:0001817 Census, Compendium Yes 141 0.193 418 59 0.141 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0001817 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0001817 Census Yes 44 0.097 259 23 0.089 0
BCL6B BCL6B Q8N143 B-cell CLL/lymphoma 6 member B protein chr17 GO:0001817 Not Cancer Driver No 79 0.165 185 28 0.151 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0001817 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0001817 Census, Compendium Yes 66 0.124 21 0 0.0 8
BPI BPI P17213 Bactericidal permeability-increasing protein chr20 GO:0001817 Not Cancer Driver No 90 0.185 49 7 0.143 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0001817 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0001817 Not Cancer Driver No 19 0.106 20 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0001817 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN1A1 BTN1A1 Q13410 Butyrophilin subfamily 1 member A1 chr6 GO:0001817 Not Cancer Driver No 116 0.221 89 16 0.18 0
BTN2A1 BTN2A1 Q7KYR7 Butyrophilin subfamily 2 member A1 chr6 GO:0001817 Not Cancer Driver No 86 0.163 38 9 0.237 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0001817 Not Cancer Driver No 92 0.176 24 2 0.083 0
BTN3A1 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0001817 Not Cancer Driver No 77 0.15 72 18 0.25 0
BTN3A2 BTN3A2 P78410 Butyrophilin subfamily 3 member A2 chr6 GO:0001817 Not Cancer Driver No 63 0.189 45 6 0.133 0
BTN3A3 BTN3A3 O00478 Butyrophilin subfamily 3 member A3 chr6 GO:0001817 Not Cancer Driver No 85 0.146 142 29 0.204 0
BTNL2_ENST00000374993 BTNL2 Q9UIR0 Butyrophilin-like protein 2 chr6 GO:0001817 Not Cancer Driver No 66 0.145 82 16 0.195 0
BTNL3 BTNL3 Q6UXE8 Butyrophilin-like protein 3 chr5 GO:0001817 Not Cancer Driver No 79 0.17 50 13 0.26 0
BTNL8 BTNL8 Q6UX41 Butyrophilin-like protein 8 chr5 GO:0001817 Not Cancer Driver No 132 0.264 84 22 0.262 0
BTNL9 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 GO:0001817 Not Cancer Driver No 69 0.129 87 4 0.046 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0001817 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0001817 Not Cancer Driver No 42 0.171 73 14 0.192 0
C1QTNF4 C1QTNF4 Q9BXJ3 Complement C1q tumor necrosis factor-related protein 4 chr11 GO:0001817 Not Cancer Driver No 25 0.076 91 4 0.044 0
C3 C3 P01024 Complement C3 chr19 GO:0001817 Not Cancer Driver No 337 0.203 287 50 0.174 12
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0001817 Not Cancer Driver No 88 0.183 72 16 0.222 0
C5 C5 P01031 Complement C5 chr9 GO:0001817 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0001817 Not Cancer Driver No 71 0.203 0 0 0.0 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0001817 Not Cancer Driver No 60 0.178 11 3 0.273 0
C5orf30_ENST00000510890 MACIR Q96GV9 Macrophage immunometabolism regulator chr5 GO:0001817 Not Cancer Driver No 26 0.126 133 20 0.15 0
C6orf106 ILRUN Q9H6K1 Protein ILRUN chr6 GO:0001817 Not Cancer Driver No 23 0.077 113 6 0.053 0
CACTIN CACTIN Q8WUQ7 Cactin chr19 GO:0001817 Not Cancer Driver No 94 0.124 503 54 0.107 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0001817 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0001817 Not Cancer Driver No 81 0.116 46 11 0.239 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0001817 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0001817 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD17 CARD17 Q5XLA6 Caspase recruitment domain-containing protein 17 chr11 GO:0001817 Not Cancer Driver No 24 0.218 22 7 0.318 0
CARD18 CARD18 P57730 Caspase recruitment domain-containing protein 18 chr11 GO:0001817 Not Cancer Driver No 24 0.267 14 1 0.071 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0001817 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0001817 Not Cancer Driver No 72 0.134 225 35 0.156 11
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0001817 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0001817 Census, Compendium Yes 142 0.296 106 12 0.113 1
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0001817 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0001817 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0001817 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN4 CCN4 O95388 CCN family member 4 chr8 GO:0001817 Not Cancer Driver No 93 0.253 20 8 0.4 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0001817 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0001817 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 GO:0001817 Not Cancer Driver No 42 0.112 60 5 0.083 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0001817 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0001817 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD200R1_ENST00000471858 CD200R1 Q8TD46 Cell surface glycoprotein CD200 receptor 1 chr3 GO:0001817 Not Cancer Driver No 87 0.268 56 12 0.214 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0001817 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0001817 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0001817 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0001817 Census Yes 29 0.1 54 9 0.167 0
CD276 CD276 Q5ZPR3 CD276 antigen chr15 GO:0001817 Not Cancer Driver No 62 0.116 139 10 0.072 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0001817 Census Yes 42 0.191 18 10 0.556 0
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0001817 Not Cancer Driver No 80 0.125 456 60 0.132 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0001817 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0001817 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0001817 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0001817 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0001817 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0001817 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD40LG CD40LG P29965 CD40 ligand chrX GO:0001817 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0001817 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0001817 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0001817 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD58 CD58 P19256 Lymphocyte function-associated antigen 3 chr1 GO:0001817 Compendium Yes 29 0.116 12 2 0.167 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0001817 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0001817 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0001817 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0001817 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0001817 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0001817 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0001817 Not Cancer Driver No 90 0.274 56 18 0.321 0
CD96 CD96 P40200 T-cell surface protein tactile chr3 GO:0001817 Not Cancer Driver No 132 0.226 165 34 0.206 1
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0001817 Not Cancer Driver No 87 0.105 488 52 0.107 2
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0001817 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0001817 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0001817 Not Cancer Driver No 13 0.087 141 12 0.085 0
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0001817 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0001817 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 GO:0001817 Not Cancer Driver No 116 0.244 42 10 0.238 0
CHID1_ENST00000436108 CHID1 Q9BWS9 Chitinase domain-containing protein 1 chr11 GO:0001817 Not Cancer Driver No 53 0.135 4 0 0.0 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0001817 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0001817 Not Cancer Driver No 74 0.099 116 9 0.078 0
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0001817 Not Cancer Driver No 43 0.196 32 3 0.094 0
CLC CLC Q05315 Galectin-10 chr19 GO:0001817 Not Cancer Driver No 29 0.204 0 0 0.0 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 GO:0001817 Not Cancer Driver No 35 0.148 22 4 0.182 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0001817 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLECL1_ENST00000327839 CLECL1 Q8IZS7 C-type lectin-like domain family 1 chr12 GO:0001817 Not Cancer Driver No 18 0.108 0 0 0.0 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0001817 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0001817 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0001817 Not Cancer Driver No 107 0.287 24 13 0.542 0
CPTP CPTP Q5TA50 Ceramide-1-phosphate transfer protein chr1 GO:0001817 Not Cancer Driver No 16 0.075 4 0 0.0 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0001817 Compendium Yes 383 0.188 151 42 0.278 0
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX GO:0001817 Census Yes 54 0.146 62 3 0.048 0
CRP CRP P02741 C-reactive protein chr1 GO:0001817 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0001817 Not Cancer Driver No 64 0.163 135 14 0.104 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0001817 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0001817 Census Yes 133 0.137 124 17 0.137 20
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0001817 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0001817 Not Cancer Driver No 41 0.091 18 1 0.056 0
CUEDC2 CUEDC2 Q9H467 CUE domain-containing protein 2 chr10 GO:0001817 Not Cancer Driver No 37 0.129 173 25 0.145 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0001817 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0001817 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0001817 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0001817 Not Cancer Driver No 17 0.149 9 1 0.111 0
CXorf40A_ENST00000423540 EOLA1 Q8TE69 Protein EOLA1 chrX GO:0001817 Not Cancer Driver No 27 0.171 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0001817 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0001817 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0001817 Census, Compendium Yes 116 0.121 213 31 0.146 3
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0001817 Not Cancer Driver No 61 0.112 31 3 0.097 40
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0001817 Census Yes 29 0.172 160 27 0.169 0
DDT_ENST00000350608 DDT P30046 D-dopachrome decarboxylase chr22 GO:0001817 Not Cancer Driver No 4 0.034 0 0 0.0 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0001817 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0001817 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0001817 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0001817 Not Cancer Driver No 118 0.128 61 10 0.164 2
DEFB114 DEFB114 Q30KQ6 Beta-defensin 114 chr6 GO:0001817 Not Cancer Driver No 31 0.449 0 0 0.0 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0001817 Not Cancer Driver No 9 0.127 3 0 0.0 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0001817 Not Cancer Driver No 69 0.089 299 19 0.064 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0001817 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0001817 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0001817 Not Cancer Driver No 62 0.091 84 8 0.095 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0001817 Compendium Yes 182 0.143 331 42 0.127 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0001817 Census, Compendium Yes 264 0.137 362 45 0.124 4
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0001817 Not Cancer Driver No 115 0.159 145 24 0.166 1
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0001817 Not Cancer Driver No 127 0.287 124 45 0.363 0
DTX4 DTX4 Q9Y2E6 E3 ubiquitin-protein ligase DTX4 chr11 GO:0001817 Not Cancer Driver No 84 0.136 323 57 0.176 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0001817 Not Cancer Driver No 32 0.14 10 1 0.1 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0001817 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0001817 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0001817 Not Cancer Driver No 149 0.134 410 51 0.124 1
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0001817 Not Cancer Driver No 39 0.146 18 3 0.167 89
ELF1 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 GO:0001817 Not Cancer Driver No 78 0.126 469 62 0.132 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0001817 Compendium Yes 171 0.175 187 39 0.209 3
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0001817 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0001817 Not Cancer Driver No 144 0.201 55 6 0.109 1
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:0001817 Not Cancer Driver No 167 0.118 967 118 0.122 0
EREG EREG O14944 Proepiregulin chr4 GO:0001817 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERMAP_ENST00000372514 ERMAP Q96PL5 Erythroid membrane-associated protein chr1 GO:0001817 Not Cancer Driver No 55 0.116 48 5 0.104 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0001817 Not Cancer Driver No 55 0.119 297 37 0.125 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0001817 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0001817 Census Yes 66 0.113 295 35 0.119 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0001817 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:0001817 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0001817 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0001817 Not Cancer Driver No 55 0.139 7 2 0.286 0
F3 F3 P13726 Tissue factor chr1 GO:0001817 Not Cancer Driver No 28 0.095 61 7 0.115 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0001817 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0001817 Not Cancer Driver No 53 0.164 78 11 0.141 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0001817 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0001817 Census Yes 51 0.165 99 30 0.303 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0001817 Not Cancer Driver No 107 0.328 88 15 0.17 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0001817 Not Cancer Driver No 100 0.148 65 8 0.123 2
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0001817 Not Cancer Driver No 45 0.15 2 0 0.0 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0001817 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0001817 Not Cancer Driver No 78 0.225 29 6 0.207 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0001817 Not Cancer Driver No 47 0.13 0 0 0.0 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0001817 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0001817 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:0001817 Compendium Yes 394 0.159 1243 185 0.149 8
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0001817 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0001817 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0001817 Not Cancer Driver No 38 0.088 186 16 0.086 10
FRMD8 FRMD8 Q9BZ67 FERM domain-containing protein 8 chr11 GO:0001817 Not Cancer Driver No 50 0.108 119 12 0.101 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0001817 Not Cancer Driver No 93 0.117 283 35 0.124 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0001817 Not Cancer Driver No 45 0.077 58 4 0.069 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0001817 Not Cancer Driver No 85 0.182 352 65 0.185 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0001817 Not Cancer Driver No 39 0.116 24 3 0.125 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0001817 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0001817 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0001817 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0001817 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0001817 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0001817 Not Cancer Driver No 92 0.155 166 27 0.163 0
GBP5 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0001817 Not Cancer Driver No 106 0.181 170 21 0.124 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0001817 Not Cancer Driver No 88 0.138 93 8 0.086 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0001817 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0001817 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0001817 Not Cancer Driver No 67 0.088 434 42 0.097 0
GLMN GLMN Q92990 Glomulin chr1 GO:0001817 Not Cancer Driver No 49 0.082 37 6 0.162 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0001817 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPATCH3 GPATCH3 Q96I76 G patch domain-containing protein 3 chr1 GO:0001817 Not Cancer Driver No 64 0.122 354 48 0.136 0
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0001817 Not Cancer Driver No 89 0.156 94 18 0.191 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0001817 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0001817 Not Cancer Driver No 82 0.203 75 19 0.253 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 GO:0001817 Not Cancer Driver No 26 0.163 160 26 0.163 0
GSDMD_ENST00000262580 GSDMD P57764 Gasdermin-D chr8 GO:0001817 Not Cancer Driver No 47 0.097 156 16 0.103 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0001817 Not Cancer Driver No 32 0.152 0 0 0.0 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0001817 Not Cancer Driver No 69 0.229 17 2 0.118 3
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0001817 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0001817 Not Cancer Driver No 91 0.096 570 50 0.088 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0001817 Not Cancer Driver No 286 0.283 631 178 0.282 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0001817 Not Cancer Driver No 173 0.125 974 135 0.139 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0001817 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0001817 Compendium Yes 233 0.32 43 16 0.372 0
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0001817 Not Cancer Driver No 85 0.205 57 10 0.175 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0001817 Census Yes 118 0.143 435 51 0.117 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0001817 Not Cancer Driver No 127 0.138 75 16 0.213 6
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0001817 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0001817 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0001817 Not Cancer Driver No 37 0.142 30 4 0.133 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0001817 Not Cancer Driver No 38 0.147 39 4 0.103 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0001817 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0001817 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0001817 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0001817 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0001817 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0001817 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMHB1 HMHB1 O97980 Minor histocompatibility protein HB-1 chr5 GO:0001817 Not Cancer Driver No 3 0.073 10 0 0.0 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0001817 Not Cancer Driver No 46 0.16 81 13 0.16 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 GO:0001817 Not Cancer Driver No 53 0.15 233 32 0.137 1
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 GO:0001817 Not Cancer Driver No 31 0.086 251 15 0.06 0
HPSE HPSE Q9Y251 Heparanase chr4 GO:0001817 Not Cancer Driver No 90 0.166 16 2 0.125 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0001817 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0001817 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0001817 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0001817 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0001817 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0001817 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0001817 Not Cancer Driver No 61 0.106 82 6 0.073 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0001817 Not Cancer Driver No 52 0.11 8 1 0.125 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0001817 Not Cancer Driver No 25 0.083 30 2 0.067 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0001817 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0001817 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0001817 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0001817 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0001817 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0001817 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0001817 Compendium Yes 55 0.112 175 22 0.126 10
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0001817 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0001817 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0001817 Not Cancer Driver No 141 0.244 298 80 0.268 0
IGF2BP2_ENST00000382199 IGF2BP2 Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 chr3 GO:0001817 Census Yes 68 0.114 237 31 0.131 0
IGF2BP3 IGF2BP3 O00425 Insulin-like growth factor 2 mRNA-binding protein 3 chr7 GO:0001817 Not Cancer Driver No 79 0.136 264 40 0.152 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0001817 Not Cancer Driver No 61 0.159 245 40 0.163 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0001817 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0001817 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0001817 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL12RB2 IL12RB2 Q99665 Interleukin-12 receptor subunit beta-2 chr1 GO:0001817 Not Cancer Driver No 129 0.15 195 31 0.159 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0001817 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0001817 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL16 IL16 Q14005 Pro-interleukin-16 chr15 GO:0001817 Not Cancer Driver No 216 0.162 959 151 0.157 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0001817 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17B IL17B Q9UHF5 Interleukin-17B chr5 GO:0001817 Not Cancer Driver No 29 0.161 48 10 0.208 0
IL17D IL17D Q8TAD2 Interleukin-17D chr13 GO:0001817 Not Cancer Driver No 9 0.045 64 1 0.016 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0001817 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 GO:0001817 Not Cancer Driver No 92 0.106 301 20 0.066 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0001817 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0001817 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0001817 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0001817 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0001817 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1R2_ENST00000393414 IL1R2 P27930 Interleukin-1 receptor type 2 chr2 GO:0001817 Not Cancer Driver No 75 0.188 32 10 0.312 0
IL1RAP_ENST00000447382 IL1RAP Q9NPH3 Interleukin-1 receptor accessory protein chr3 GO:0001817 Not Cancer Driver No 79 0.139 50 11 0.22 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0001817 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL1RL2 IL1RL2 Q9HB29 Interleukin-1 receptor-like 2 chr2 GO:0001817 Not Cancer Driver No 114 0.198 11 4 0.364 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0001817 Census Yes 24 0.157 6 1 0.167 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0001817 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0001817 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0001817 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0001817 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0001817 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0001817 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0001817 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 GO:0001817 Not Cancer Driver No 44 0.278 13 3 0.231 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0001817 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL37 IL37 Q9NZH6 Interleukin-37 chr2 GO:0001817 Not Cancer Driver No 56 0.257 71 13 0.183 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0001817 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0001817 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 GO:0001817 Not Cancer Driver No 92 0.219 23 5 0.217 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0001817 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0001817 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0001817 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0001817 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL9 IL9 P15248 Interleukin-9 chr5 GO:0001817 Not Cancer Driver No 12 0.083 4 0 0.0 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0001817 Not Cancer Driver No 112 0.169 553 98 0.177 1
INHA INHA P05111 Inhibin alpha chain chr2 GO:0001817 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0001817 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0001817 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0001817 Not Cancer Driver No 176 0.148 578 90 0.156 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0001817 Not Cancer Driver No 183 0.11 351 35 0.1 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0001817 Compendium Yes 71 0.1 337 39 0.116 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0001817 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0001817 Compendium Yes 49 0.151 228 31 0.136 2
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0001817 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0001817 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 GO:0001817 Not Cancer Driver No 93 0.187 237 64 0.27 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0001817 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0001817 Not Cancer Driver No 80 0.188 77 20 0.26 2
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0001817 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0001817 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0001817 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0001817 Census Yes 153 0.146 92 9 0.098 0
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0001817 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 GO:0001817 Not Cancer Driver No 126 0.164 26 3 0.115 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0001817 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0001817 Census, Compendium Yes 167 0.149 63 10 0.159 7
JPH4_ENST00000356300 JPH4 Q96JJ6 Junctophilin-4 chr14 GO:0001817 Not Cancer Driver No 57 0.091 516 54 0.105 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0001817 Not Cancer Driver No 65 0.127 173 21 0.121 3
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0001817 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0001817 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0001817 Not Cancer Driver No 38 0.176 0 0 0.0 0
KPNA6 KPNA6 O60684 Importin subunit alpha-7 chr1 GO:0001817 Not Cancer Driver No 70 0.131 97 17 0.175 0
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 GO:0001817 Not Cancer Driver No 50 0.116 4 0 0.0 1
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0001817 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0001817 Not Cancer Driver No 10 0.11 17 0 0.0 0
LAPTM4B_ENST00000619747 LAPTM4B Q86VI4 Lysosomal-associated transmembrane protein 4B chr8 GO:0001817 Not Cancer Driver No 24 0.076 73 5 0.068 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0001817 Not Cancer Driver No 46 0.176 16 6 0.375 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0001817 Not Cancer Driver No 84 0.175 6 0 0.0 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0001817 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0001817 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:0001817 Not Cancer Driver No 14 0.103 54 5 0.093 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0001817 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGALS9B_ENST00000423676 LGALS9B Q3B8N2 Galectin-9B chr17 GO:0001817 Not Cancer Driver No 43 0.121 86 19 0.221 0
LGALS9C LGALS9C Q6DKI2 Galectin-9C chr17 GO:0001817 Not Cancer Driver No 32 0.09 80 6 0.075 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0001817 Not Cancer Driver No 108 0.114 16 3 0.188 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0001817 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRA4 LILRA4 P59901 Leukocyte immunoglobulin-like receptor subfamily A member 4 chr19 GO:0001817 Not Cancer Driver No 124 0.248 109 26 0.239 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0001817 Not Cancer Driver No 79 0.264 98 19 0.194 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0001817 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0001817 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0001817 Not Cancer Driver No 162 0.362 277 115 0.415 0
LITAF_ENST00000570904 LITAF Q99732 Lipopolysaccharide-induced tumor necrosis factor-alpha factor chr16 GO:0001817 Not Cancer Driver No 21 0.13 67 6 0.09 5
LPL LPL P06858 Lipoprotein lipase chr8 GO:0001817 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRRC19 LRRC19 Q9H756 Leucine-rich repeat-containing protein 19 chr9 GO:0001817 Not Cancer Driver No 37 0.1 30 3 0.1 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0001817 Not Cancer Driver No 130 0.196 28 4 0.143 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0001817 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0001817 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTB LTB Q06643 Lymphotoxin-beta chr6 GO:0001817 Compendium Yes 33 0.135 91 13 0.143 0
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 GO:0001817 Not Cancer Driver No 300 0.174 518 78 0.151 0
LTF LTF P02788 Lactotransferrin chr3 GO:0001817 Not Cancer Driver No 131 0.185 21 4 0.19 0
LUM LUM P51884 Lumican chr12 GO:0001817 Not Cancer Driver No 108 0.32 1 0 0.0 0
LY9 LY9 Q9HBG7 T-lymphocyte surface antigen Ly-9 chr1 GO:0001817 Not Cancer Driver No 141 0.215 249 49 0.197 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0001817 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0001817 Census Yes 95 0.186 84 12 0.143 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0001817 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0001817 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0001817 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0001817 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0001817 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0001817 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0001817 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0001817 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKBP1 MAPKBP1 O60336 Mitogen-activated protein kinase-binding protein 1 chr15 GO:0001817 Not Cancer Driver No 166 0.11 786 67 0.085 0
MAST2 MAST2 Q6P0Q8 Microtubule-associated serine/threonine-protein kinase 2 chr1 GO:0001817 Not Cancer Driver No 187 0.104 1326 133 0.1 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0001817 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0001817 Not Cancer Driver No 52 0.171 304 52 0.171 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0001817 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCOLN2 MCOLN2 Q8IZK6 Mucolipin-2 chr1 GO:0001817 Not Cancer Driver No 93 0.164 0 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0001817 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEFV MEFV O15553 Pyrin chr16 GO:0001817 Not Cancer Driver No 196 0.251 397 119 0.3 47
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0001817 Not Cancer Driver No 175 0.175 159 31 0.195 3
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0001817 Not Cancer Driver No 4 0.035 0 0 0.0 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0001817 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0001817 Not Cancer Driver No 73 0.156 115 19 0.165 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0001817 Not Cancer Driver No 180 0.442 172 76 0.442 0
MOG_ENST00000376917 MOG Q16653 Myelin-oligodendrocyte glycoprotein chr6 GO:0001817 Not Cancer Driver No 57 0.231 13 2 0.154 1
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0001817 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0001817 Census, Compendium Yes 37 0.125 47 1 0.021 2
N4BP1 N4BP1 O75113 NEDD4-binding protein 1 chr16 GO:0001817 Not Cancer Driver No 108 0.121 432 58 0.134 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0001817 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0001817 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0001817 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 GO:0001817 Not Cancer Driver No 45 0.121 111 8 0.072 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0001817 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0001817 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBIL1 NFKBIL1 Q9UBC1 NF-kappa-B inhibitor-like protein 1 chr6 GO:0001817 Not Cancer Driver No 37 0.097 316 33 0.104 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0001817 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0001817 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0001817 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0001817 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0001817 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP2 NLRP2 Q9NX02 NACHT, LRR and PYD domains-containing protein 2 chr19 GO:0001817 Not Cancer Driver No 257 0.242 60 15 0.25 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0001817 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0001817 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0001817 Not Cancer Driver No 300 0.306 71 20 0.282 9
NLRP9 NLRP9 Q7RTR0 NACHT, LRR and PYD domains-containing protein 9 chr19 GO:0001817 Not Cancer Driver No 247 0.249 0 0 0.0 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0001817 Not Cancer Driver No 158 0.162 94 13 0.138 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0001817 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0001817 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0001817 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0001817 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0001817 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0001817 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:0001817 Not Cancer Driver No 78 0.128 47 8 0.17 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0001817 Not Cancer Driver No 47 0.118 118 9 0.076 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0001817 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0001817 Census Yes 83 0.133 298 37 0.124 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0001817 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS2 OAS2 P29728 2'-5'-oligoadenylate synthase 2 chr12 GO:0001817 Not Cancer Driver No 141 0.196 47 14 0.298 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0001817 Not Cancer Driver No 139 0.128 147 17 0.116 0
ORM1 ORM1 P02763 Alpha-1-acid glycoprotein 1 chr9 GO:0001817 Not Cancer Driver No 38 0.189 23 2 0.087 0
ORM2 ORM2 P19652 Alpha-1-acid glycoprotein 2 chr9 GO:0001817 Not Cancer Driver No 38 0.189 22 2 0.091 0
OSM OSM P13725 Oncostatin-M chr22 GO:0001817 Not Cancer Driver No 43 0.171 114 24 0.211 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:0001817 Not Cancer Driver No 55 0.096 430 39 0.091 4
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0001817 Not Cancer Driver No 124 0.147 537 87 0.162 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0001817 Not Cancer Driver No 51 0.086 14 2 0.143 0
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 GO:0001817 Not Cancer Driver No 23 0.128 3 0 0.0 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0001817 Not Cancer Driver No 54 0.127 45 7 0.156 2
PANX2 PANX2 Q96RD6 Pannexin-2 chr22 GO:0001817 Not Cancer Driver No 73 0.108 293 14 0.048 0
PANX3 PANX3 Q96QZ0 Pannexin-3 chr11 GO:0001817 Not Cancer Driver No 92 0.235 10 4 0.4 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0001817 Not Cancer Driver No 11 0.058 30 0 0.0 5
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0001817 Census, Compendium Yes 33 0.121 41 13 0.317 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0001817 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0001817 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0001817 Not Cancer Driver No 86 0.106 464 54 0.116 12
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0001817 Census Yes 160 0.124 948 116 0.122 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0001817 Not Cancer Driver No 13 0.129 0 0 0.0 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0001817 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0001817 Not Cancer Driver No 111 0.193 160 28 0.175 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0001817 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0001817 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0001817 Census, Compendium Yes 154 0.213 268 61 0.228 2
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0001817 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0001817 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0001817 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0001817 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0001817 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 GO:0001817 Not Cancer Driver No 70 0.143 62 7 0.113 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 GO:0001817 Not Cancer Driver No 46 0.091 76 10 0.132 0
PML PML P29590 Protein PML chr15 GO:0001817 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0001817 Not Cancer Driver No 38 0.131 29 2 0.069 5
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:0001817 Not Cancer Driver No 185 0.127 347 45 0.13 3
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 GO:0001817 Not Cancer Driver No 155 0.112 113 17 0.15 15
POLR3B POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 GO:0001817 Not Cancer Driver No 164 0.145 117 20 0.171 8
POLR3C POLR3C Q9BUI4 DNA-directed RNA polymerase III subunit RPC3 chr1 GO:0001817 Not Cancer Driver No 60 0.112 161 21 0.13 0
POLR3D POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 GO:0001817 Not Cancer Driver No 33 0.083 303 24 0.079 0
POLR3F POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:0001817 Not Cancer Driver No 20 0.063 55 5 0.091 0
POLR3G POLR3G O15318 DNA-directed RNA polymerase III subunit RPC7 chr5 GO:0001817 Not Cancer Driver No 28 0.126 187 15 0.08 0
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0001817 Not Cancer Driver No 50 0.187 198 38 0.192 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 GO:0001817 Census Yes 59 0.23 181 45 0.249 0
POU2F2 POU2F2 P09086 POU domain, class 2, transcription factor 2 chr19 GO:0001817 Compendium Yes 82 0.171 387 67 0.173 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0001817 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:0001817 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPP1R11 PPP1R11 O60927 E3 ubiquitin-protein ligase PPP1R11 chr6 GO:0001817 Not Cancer Driver No 17 0.135 126 17 0.135 0
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0001817 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRG3 PRG3 Q9Y2Y8 Proteoglycan 3 chr11 GO:0001817 Not Cancer Driver No 40 0.178 60 12 0.2 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0001817 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0001817 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0001817 Compendium Yes 118 0.134 246 34 0.138 0
PRNP PRNP P04156 Major prion protein chr20 GO:0001817 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0001817 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:0001817 Not Cancer Driver No 125 0.293 40 8 0.2 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0001817 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0001817 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0001817 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0001817 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0001817 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0001817 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0001817 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0001817 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0001817 Not Cancer Driver No 250 0.128 829 111 0.134 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0001817 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYDC1 PYDC1 Q8WXC3 Pyrin domain-containing protein 1 chr16 GO:0001817 Not Cancer Driver No 28 0.315 0 0 0.0 0
PYDC2 PYDC2 Q56P42 Pyrin domain-containing protein 2 chr3 GO:0001817 Not Cancer Driver No 20 0.206 26 5 0.192 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0001817 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0001817 Not Cancer Driver No 16 0.078 38 2 0.053 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0001817 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0001817 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0001817 Not Cancer Driver No 41 0.123 62 10 0.161 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0001817 Census, Compendium Yes 70 0.152 167 14 0.084 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0001817 Not Cancer Driver No 96 0.12 191 12 0.063 1
REL REL Q04864 Proto-oncogene c-Rel chr2 GO:0001817 Census Yes 68 0.11 363 43 0.118 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0001817 Compendium Yes 75 0.136 400 48 0.12 0
RELB RELB Q01201 Transcription factor RelB chr19 GO:0001817 Not Cancer Driver No 65 0.112 348 39 0.112 0
RFTN1 RFTN1 Q14699 Raftlin chr3 GO:0001817 Not Cancer Driver No 87 0.151 319 44 0.138 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0001817 Not Cancer Driver No 9 0.066 81 7 0.086 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0001817 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0001817 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0001817 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0001817 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0001817 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0001817 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0001817 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF216_ENST00000425013 RNF216 Q9NWF9 E3 ubiquitin-protein ligase RNF216 chr7 GO:0001817 Not Cancer Driver No 108 0.125 415 57 0.137 2
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 GO:0001817 Not Cancer Driver No 44 0.102 71 7 0.099 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0001817 Not Cancer Driver No 145 0.104 732 81 0.111 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0001817 Not Cancer Driver No 57 0.109 182 17 0.093 4
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0001817 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0001817 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0001817 Not Cancer Driver No 97 0.121 187 18 0.096 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0001817 Not Cancer Driver No 68 0.188 22 1 0.045 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0001817 Census, Compendium Yes 81 0.179 360 58 0.161 2
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0001817 Not Cancer Driver No 12 0.122 6 0 0.0 0
S1PR3 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0001817 Not Cancer Driver No 69 0.183 28 4 0.143 0
SAA1 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0001817 Not Cancer Driver No 23 0.189 25 5 0.2 0
SARS_ENST00000234677 SARS1 P49591 Serine--tRNA ligase, cytoplasmic chr1 GO:0001817 Not Cancer Driver No 56 0.109 83 4 0.048 1
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0001817 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0001817 Not Cancer Driver No 12 0.132 14 2 0.143 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0001817 Not Cancer Driver No 10 0.069 73 9 0.123 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0001817 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0001817 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0001817 Not Cancer Driver No 7 0.037 122 6 0.049 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0001817 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINB1 SERPINB1 P30740 Leukocyte elastase inhibitor chr6 GO:0001817 Not Cancer Driver No 39 0.103 14 0 0.0 0
SERPINB7 SERPINB7 O75635 Serpin B7 chr18 GO:0001817 Not Cancer Driver No 100 0.263 30 8 0.267 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0001817 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0001817 Not Cancer Driver No 62 0.126 112 21 0.188 1
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0001817 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SETD4 SETD4 Q9NVD3 SET domain-containing protein 4 chr21 GO:0001817 Not Cancer Driver No 51 0.116 27 2 0.074 0
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0001817 Not Cancer Driver No 66 0.176 274 53 0.193 0
SIGIRR_ENST00000397632 SIGIRR Q6IA17 Single Ig IL-1-related receptor chr11 GO:0001817 Not Cancer Driver No 27 0.066 85 4 0.047 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0001817 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0001817 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0001817 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF6 SLAMF6 Q96DU3 SLAM family member 6 chr1 GO:0001817 Not Cancer Driver No 69 0.208 60 14 0.233 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0001817 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0001817 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 GO:0001817 Not Cancer Driver No 62 0.122 35 1 0.029 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0001817 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0001817 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0001817 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0001817 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0001817 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0001817 Not Cancer Driver No 84 0.157 297 46 0.155 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0001817 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0001817 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0001817 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0001817 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0001817 Not Cancer Driver No 36 0.109 73 4 0.055 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0001817 Not Cancer Driver No 311 0.132 869 123 0.142 0
SRGN SRGN P10124 Serglycin chr10 GO:0001817 Not Cancer Driver No 25 0.158 87 13 0.149 0
SSC5D SSC5D A1L4H1 Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D chr19 GO:0001817 Not Cancer Driver No 81 0.051 1194 70 0.059 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0001817 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0001817 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0001817 Census, Compendium Yes 93 0.118 144 19 0.132 5
STMP1 STMP1 E0CX11 Short transmembrane mitochondrial protein 1 chr7 GO:0001817 Not Cancer Driver No 1 0.021 12 0 0.0 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0001817 Not Cancer Driver No 40 0.112 117 9 0.077 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0001817 Not Cancer Driver No 246 0.282 269 71 0.264 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 GO:0001817 Not Cancer Driver No 145 0.167 142 18 0.127 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0001817 Census Yes 96 0.151 131 27 0.206 5
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0001817 Not Cancer Driver No 64 0.148 105 23 0.219 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0001817 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0001817 Not Cancer Driver No 70 0.131 348 50 0.144 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0001817 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0001817 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0001817 Not Cancer Driver No 45 0.109 96 14 0.146 1
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0001817 Not Cancer Driver No 188 0.161 320 58 0.181 0
TIA1 TIA1 P31483 Cytotoxic granule associated RNA binding protein TIA1 chr2 GO:0001817 Not Cancer Driver No 39 0.101 130 12 0.092 2
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0001817 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIGIT TIGIT Q495A1 T-cell immunoreceptor with Ig and ITIM domains chr3 GO:0001817 Not Cancer Driver No 60 0.246 28 4 0.143 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0001817 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR10_ENST00000508334 TLR10 Q9BXR5 Toll-like receptor 10 chr4 GO:0001817 Not Cancer Driver No 122 0.15 9 1 0.111 0
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0001817 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0001817 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0001817 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0001817 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0001817 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0001817 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0001817 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0001817 Not Cancer Driver No 180 0.173 30 7 0.233 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0001817 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 GO:0001817 Not Cancer Driver No 24 0.11 15 3 0.2 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0001817 Not Cancer Driver No 26 0.099 9 1 0.111 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0001817 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0001817 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0001817 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0001817 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0001817 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0001817 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFRSF21 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0001817 Not Cancer Driver No 98 0.15 280 46 0.164 0
TNFRSF8 TNFRSF8 P28908 Tumor necrosis factor receptor superfamily member 8 chr1 GO:0001817 Not Cancer Driver No 95 0.16 286 35 0.122 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0001817 Not Cancer Driver No 28 0.153 1 0 0.0 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0001817 Not Cancer Driver No 59 0.097 140 8 0.057 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0001817 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 GO:0001817 Not Cancer Driver No 75 0.109 507 60 0.118 4
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0001817 Compendium Yes 61 0.107 101 9 0.089 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0001817 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0001817 Not Cancer Driver No 63 0.134 240 33 0.138 1
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0001817 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0001817 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 GO:0001817 Not Cancer Driver No 64 0.187 43 5 0.116 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0001817 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0001817 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0001817 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0001817 Census Yes 59 0.115 87 11 0.126 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0001817 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM38 TRIM38 O00635 E3 ubiquitin-protein ligase TRIM38 chr6 GO:0001817 Not Cancer Driver No 62 0.133 47 8 0.17 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0001817 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0001817 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0001817 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0001817 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0001817 Not Cancer Driver No 53 0.15 44 6 0.136 0
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0001817 Not Cancer Driver No 27 0.17 16 0 0.0 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0001817 Not Cancer Driver No 5 0.03 1 0 0.0 0
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0001817 Not Cancer Driver No 10 0.091 31 3 0.097 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0001817 Not Cancer Driver No 23 0.114 132 11 0.083 7
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0001817 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0001817 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0001817 Not Cancer Driver No 148 0.125 213 29 0.136 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0001817 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 GO:0001817 Not Cancer Driver No 101 0.153 27 8 0.296 0
UBE2J1 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 GO:0001817 Not Cancer Driver No 33 0.104 158 20 0.127 0
UCN UCN P55089 Urocortin chr2 GO:0001817 Not Cancer Driver No 7 0.056 61 4 0.066 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0001817 Not Cancer Driver No 26 0.085 100 7 0.07 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 GO:0001817 Not Cancer Driver No 33 0.097 2 0 0.0 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0001817 Not Cancer Driver No 73 0.183 70 13 0.186 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0001817 Not Cancer Driver No 52 0.167 135 19 0.141 0
VTCN1 VTCN1 Q7Z7D3 V-set domain-containing T-cell activation inhibitor 1 chr1 GO:0001817 Not Cancer Driver No 43 0.152 3 2 0.667 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0001817 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0001817 Not Cancer Driver No 66 0.174 0 0 0.0 2
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0001817 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0001817 Not Cancer Driver No 28 0.246 35 11 0.314 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0001817 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0001817 Compendium Yes 151 0.204 433 80 0.185 4
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0001817 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0001817 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0001817 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0001817 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:0001817 Not Cancer Driver No 50 0.05 772 27 0.035 0
ZNF287 ZNF287 Q9HBT7 Zinc finger protein 287 chr17 GO:0001817 Not Cancer Driver No 103 0.135 168 32 0.19 0
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0001817 Not Cancer Driver No 8 0.047 153 8 0.052 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0001817 Not Cancer Driver No 55 0.13 56 11 0.196 1