Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 42 | 10 | 10 | 16 |
ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 131 | 244 | 42 | 42 | 8 |
ACTR3 | ACTR3 | P61158 | Actin-related protein 3 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 32 | 16 | 2 | 2 | 0 |
ADRA1B | ADRA1B | P35368 | Alpha-1B adrenergic receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 53 | 132 | 1 | 1 | 0 |
AGAP3_ENST00000622464 | AGAP3 | Q96P47 | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 | chr7 | Not Cancer Driver | No | 1 | hippie | 116 | 404 | 55 | 55 | 0 |
AHSA1 | AHSA1 | O95433 | Activator of 90 kDa heat shock protein ATPase homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 146 | 17 | 17 | 0 |
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
APEH | APEH | P13798 | Acylamino-acid-releasing enzyme | chr3 | Not Cancer Driver | No | 1 | hippie | 76 | 98 | 6 | 6 | 0 |
AQP3 | AQP3 | Q92482 | Aquaporin-3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 12 | 0 | 0 | 0 |
ARPC4_ENST00000397261 | ARPC4 | P59998 | Actin-related protein 2/3 complex subunit 4 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 3 | 0 | 0 | 0 |
ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 46 | 122 | 22 | 22 | 0 |
ATF3_ENST00000366987 | ATF3 | P18847 | Cyclic AMP-dependent transcription factor ATF-3 | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 118 | 14 | 14 | 0 |
ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 79 | 239 | 25 | 25 | 1 |
ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 25 | 6 | 6 | 1 |
ATG7 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | Compendium | Yes | 1 | hippie | 77 | 53 | 8 | 8 | 6 |
ATP6V1C1_ENST00000518738 | ATP6V1C1 | P21283 | V-type proton ATPase subunit C 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 54 | 17 | 3 | 3 | 0 |
B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | Census | Yes | 1 | hippie | 44 | 259 | 23 | 23 | 0 |
BMX_ENST00000342014 | BMX | P51813 | Cytoplasmic tyrosine-protein kinase BMX | chrX | Not Cancer Driver | No | 1 | hippie | 106 | 172 | 27 | 27 | 0 |
BPIFB3 | BPIFB3 | P59826 | BPI fold-containing family B member 3 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 8 | 1 | 1 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
C3orf18_ENST00000426034 | C3orf18 | Q9UK00 | Uncharacterized protein C3orf18 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 111 | 19 | 19 | 0 |
CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | Not Cancer Driver | No | 1 | hippie | 57 | 84 | 10 | 10 | 0 |
CAMK2G_ENST00000423381 | CAMK2G | Q13555 | Calcium/calmodulin-dependent protein kinase type II subunit gamma | chr10 | Not Cancer Driver | No | 1 | hippie | 68 | 145 | 14 | 14 | 1 |
CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 161 | 88 | 7 | 7 | 0 |
CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 334 | 38 | 38 | 0 |
CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 84 | 603 | 72 | 72 | 0 |
CASP12 | CASP12 | Q6UXS9 | Inactive caspase-12 | chr11 | Not Cancer Driver | No | 1 | intact | 12 | 31 | 1 | 1 | 0 |
CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | Census | Yes | 1 | hippie | 32 | 62 | 5 | 5 | 0 |
CASP7_ENST00000345633 | CASP7 | P55210 | Caspase-7 | chr10 | Not Cancer Driver | No | 1 | hippie | 38 | 73 | 10 | 10 | 0 |
CCDC8 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 96 | 505 | 91 | 91 | 0 |
CCR1 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 69 | 14 | 5 | 5 | 0 |
CCR5 | CCR5 | P51681 | C-C chemokine receptor type 5 | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 0 | 0 | 0 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
CELA3A | CELA3A | P09093 | Chymotrypsin-like elastase family member 3A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 12 | 2 | 2 | 0 |
CHCHD3 | CHCHD3 | Q9NX63 | MICOS complex subunit MIC19 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 143 | 16 | 16 | 0 |
CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | hippie | 335 | 157 | 130 | 130 | 13 |
CIAPIN1 | CIAPIN1 | Q6FI81 | Anamorsin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 119 | 8 | 8 | 0 |
CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 21 | 1 | 1 | 0 |
COL6A1 | COL6A1 | P12109 | Collagen alpha-1(VI) chain | chr21 | Not Cancer Driver | No | 1 | hippie | 145 | 434 | 61 | 61 | 12 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | Census, Compendium | Yes | 1 | hippie | 412 | 1796 | 247 | 247 | 33 |
CSE1L | CSE1L | P55060 | Exportin-2 | chr20 | Not Cancer Driver | No | 1 | hippie | 109 | 32 | 5 | 5 | 0 |
CSF2RB | CSF2RB | P32927 | Cytokine receptor common subunit beta | chr22 | Not Cancer Driver | No | 1 | hippie | 204 | 541 | 120 | 120 | 0 |
CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 46 | 3 | 3 | 0 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
CTNNBL1 | CTNNBL1 | Q8WYA6 | Beta-catenin-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 72 | 158 | 24 | 24 | 0 |
CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | Not Cancer Driver | No | 1 | hippie | 78 | 465 | 56 | 56 | 0 |
CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 64 | 102 | 2 | 2 | 0 |
CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | Not Cancer Driver | No | 1 | intact, hippie | 138 | 207 | 38 | 38 | 2 |
CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | Census, Compendium | Yes | 1 | hippie | 62 | 5 | 1 | 1 | 0 |
DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 84 | 510 | 73 | 73 | 0 |
DCAF13_ENST00000612750 | DCAF13 | Q9NV06 | DDB1- and CUL4-associated factor 13 | chr8 | Not Cancer Driver | No | 1 | hippie | 85 | 101 | 18 | 18 | 0 |
DCTN1 | DCTN1 | Q14203 | Dynactin subunit 1 | chr2 | Census | Yes | 1 | intact, hippie | 172 | 817 | 111 | 111 | 11 |
DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | Not Cancer Driver | No | 1 | intact | 126 | 50 | 8 | 8 | 4 |
DDR1_ENST00000324771 | DDR1 | Q08345 | Epithelial discoidin domain-containing receptor 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 123 | 253 | 49 | 49 | 0 |
DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
DDX6 | DDX6 | P26196 | Probable ATP-dependent RNA helicase DDX6 | chr11 | Census, Compendium | Yes | 1 | hippie | 44 | 129 | 7 | 7 | 5 |
DES | DES | P17661 | Desmin | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 71 | 264 | 41 | 41 | 35 |
DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 0 | 0 | 0 | 6 |
DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 152 | 21 | 21 | 0 |
DNAJC6_ENST00000395325 | DNAJC6 | O75061 | Putative tyrosine-protein phosphatase auxilin | chr1 | Not Cancer Driver | No | 1 | hippie | 165 | 455 | 82 | 82 | 1 |
DOCK4 | DOCK4 | Q8N1I0 | Dedicator of cytokinesis protein 4 | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 331 | 397 | 80 | 80 | 0 |
DOT1L | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | Compendium | Yes | 1 | hippie | 178 | 988 | 118 | 118 | 0 |
DTX3L | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | Not Cancer Driver | No | 1 | hippie | 86 | 260 | 24 | 24 | 0 |
DUSP2 | DUSP2 | Q05923 | Dual specificity protein phosphatase 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 24 | 23 | 3 | 3 | 0 |
DUSP3 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 21 | 4 | 1 | 1 | 0 |
E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 272 | 23 | 23 | 0 |
EEF1AKMT3 | EEF1AKMT3 | Q96AZ1 | EEF1A lysine methyltransferase 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 33 | 1 | 1 | 0 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EIF1AD | EIF1AD | Q8N9N8 | Probable RNA-binding protein EIF1AD | chr11 | Not Cancer Driver | No | 2 | intact, hippie | 14 | 99 | 10 | 10 | 0 |
EIF2AK2_ENST00000395127 | EIF2AK2 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 188 | 22 | 22 | 0 |
ELP2_ENST00000358232 | ELP2 | Q6IA86 | Elongator complex protein 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 65 | 16 | 2 | 2 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | Census, Compendium | Yes | 1 | hippie | 275 | 314 | 41 | 41 | 1 |
ERP44 | ERP44 | Q9BS26 | Endoplasmic reticulum resident protein 44 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 43 | 43 | 3 | 3 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 2 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
ETFB_ENST00000309244 | ETFB | P38117 | Electron transfer flavoprotein subunit beta | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 38 | 4 | 4 | 2 |
FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 45 | 10 | 10 | 1 |
FANCC | FANCC | Q00597 | Fanconi anemia group C protein | chr9 | Census, Compendium | Yes | 1 | hippie | 66 | 13 | 1 | 1 | 3 |
FANCE | FANCE | Q9HB96 | Fanconi anemia group E protein | chr6 | Census | Yes | 1 | hippie | 47 | 199 | 22 | 22 | 0 |
FARSB | FARSB | Q9NSD9 | Phenylalanine--tRNA ligase beta subunit | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 71 | 0 | 0 | 0 | 8 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | Census, Compendium | Yes | 1 | hippie | 173 | 241 | 26 | 26 | 37 |
FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | hippie | 113 | 162 | 28 | 28 | 0 |
FLT1 | FLT1 | P17948 | Vascular endothelial growth factor receptor 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 299 | 103 | 20 | 20 | 0 |
FOS | FOS | P01100 | Protein c-Fos | chr14 | Not Cancer Driver | No | 1 | hippie | 45 | 245 | 33 | 33 | 0 |
FOXA3 | FOXA3 | P55318 | Hepatocyte nuclear factor 3-gamma | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 232 | 40 | 40 | 0 |
FTH1_ENST00000620041 | FTH1 | P02794 | Ferritin heavy chain | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 57 | 7 | 7 | 0 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | Census, Compendium | Yes | 1 | intact, hippie | 111 | 364 | 87 | 87 | 2 |
GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 288 | 42 | 42 | 62 |
GGH | GGH | Q92820 | Gamma-glutamyl hydrolase | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 5 | 0 | 0 | 0 |
GLO1 | GLO1 | Q04760 | Lactoylglutathione lyase | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 46 | 7 | 7 | 0 |
GNB2 | GNB2 | P62879 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 50 | 21 | 0 | 0 | 7 |
GPR45 | GPR45 | Q9Y5Y3 | Probable G-protein coupled receptor 45 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 0 | 0 | 0 | 0 |
GREB1_ENST00000234142 | GREB1 | Q4ZG55 | Protein GREB1 | chr2 | Not Cancer Driver | No | 1 | intact | 313 | 371 | 67 | 67 | 0 |
GRN | GRN | P28799 | Progranulin | chr17 | Not Cancer Driver | No | 1 | hippie | 76 | 29 | 6 | 6 | 1 |
GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | Not Cancer Driver | No | 1 | hippie | 55 | 180 | 8 | 8 | 0 |
GSPT2 | GSPT2 | Q8IYD1 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | chrX | Not Cancer Driver | No | 1 | hippie | 108 | 270 | 47 | 47 | 0 |
GSTK1_ENST00000358406 | GSTK1 | Q9Y2Q3 | Glutathione S-transferase kappa 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 33 | 30 | 3 | 3 | 0 |
GTF2I | GTF2I | P78347 | General transcription factor II-I | chr7 | Compendium | Yes | 1 | hippie | 74 | 365 | 27 | 27 | 0 |
GYPA_ENST00000360771 | GYPA | P02724 | Glycophorin-A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 94 | 31 | 31 | 0 |
HADH_ENST00000309522 | HADH | Q16836 | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 22 | 5 | 5 | 3 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
HDAC3 | HDAC3 | O15379 | Histone deacetylase 3 | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 61 | 8 | 8 | 0 |
HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 749 | 132 | 132 | 0 |
HIRIP3 | HIRIP3 | Q9BW71 | HIRA-interacting protein 3 | chr16 | Not Cancer Driver | No | 1 | hippie | 71 | 539 | 70 | 70 | 0 |
HIST1H1B | H1-5 | P16401 | Histone H1.5 | chr6 | Not Cancer Driver | No | 1 | intact | 66 | 224 | 66 | 66 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HLA-DRB5 | HLA-DRB5 | Q30154 | HLA class II histocompatibility antigen, DR beta 5 chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 18 | 2 | 2 | 0 |
HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 25 | 6 | 6 | 0 |
HSD17B4_ENST00000256216 | HSD17B4 | P51659 | Peroxisomal multifunctional enzyme type 2 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 99 | 82 | 12 | 12 | 4 |
HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 59 | 335 | 37 | 37 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 100 | 254 | 43 | 43 | 0 |
HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 268 | 35 | 35 | 0 |
HSPA4L_ENST00000508776 | HSPA4L | O95757 | Heat shock 70 kDa protein 4L | chr4 | Not Cancer Driver | No | 1 | hippie | 105 | 266 | 28 | 28 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
IDE | IDE | P14735 | Insulin-degrading enzyme | chr10 | Not Cancer Driver | No | 1 | hippie | 90 | 96 | 8 | 8 | 0 |
IFNA14 | IFNA14 | P01570 | Interferon alpha-14 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 1 | 1 | 1 | 0 |
IFNA5 | IFNA5 | P01569 | Interferon alpha-5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 1 | 0 | 0 | 0 |
IFNAR1 | IFNAR1 | P17181 | Interferon alpha/beta receptor 1 | chr21 | Compendium | Yes | 1 | intact, hippie | 55 | 50 | 6 | 6 | 0 |
IFNAR2 | IFNAR2 | P48551 | Interferon alpha/beta receptor 2 | chr21 | Not Cancer Driver | No | 2 | intact, hippie | 58 | 199 | 24 | 24 | 0 |
IFNGR1 | IFNGR1 | P15260 | Interferon gamma receptor 1 | chr6 | Compendium | Yes | 4 | intact, hippie | 55 | 175 | 22 | 22 | 10 |
IFNL1 | IFNL1 | Q8IU54 | Interferon lambda-1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 49 | 8 | 8 | 0 |
IFNL3 | IFNL3 | Q8IZI9 | Interferon lambda-3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 26 | 5 | 5 | 0 |
IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | Not Cancer Driver | No | 1 | hippie | 51 | 193 | 28 | 28 | 0 |
IL13RA2_ENST00000243213 | IL13RA2 | Q14627 | Interleukin-13 receptor subunit alpha-2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 0 | 0 | 0 | 0 |
IL27RA | IL27RA | Q6UWB1 | Interleukin-27 receptor subunit alpha | chr19 | Not Cancer Driver | No | 1 | hippie | 91 | 167 | 23 | 23 | 0 |
IL2RB | IL2RB | P14784 | Interleukin-2 receptor subunit beta | chr22 | Not Cancer Driver | No | 1 | hippie | 81 | 182 | 33 | 33 | 1 |
IL2RG | IL2RG | P31785 | Cytokine receptor common subunit gamma | chrX | Not Cancer Driver | No | 1 | hippie | 56 | 32 | 6 | 6 | 33 |
IL6ST_ENST00000336909 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | Census, Compendium | Yes | 2 | intact, hippie | 102 | 315 | 40 | 40 | 2 |
INA | INA | Q16352 | Alpha-internexin | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 256 | 43 | 43 | 0 |
IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | Compendium | Yes | 1 | hippie | 71 | 337 | 39 | 39 | 0 |
IRF1 | IRF1 | P10914 | Interferon regulatory factor 1 | chr5 | Compendium | Yes | 1 | hippie | 49 | 228 | 31 | 31 | 2 |
IRF2 | IRF2 | P14316 | Interferon regulatory factor 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 85 | 288 | 73 | 73 | 0 |
IRF9 | IRF9 | Q00978 | Interferon regulatory factor 9 | chr14 | Not Cancer Driver | No | 1 | hippie | 48 | 204 | 15 | 15 | 0 |
ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | Not Cancer Driver | No | 1 | hippie | 12 | 24 | 2 | 2 | 0 |
ITGAV | ITGAV | P06756 | Integrin alpha-V | chr2 | Census | Yes | 1 | hippie | 153 | 92 | 9 | 9 | 0 |
JAK1 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | Census, Compendium | Yes | 4 | intact, hippie | 147 | 120 | 7 | 7 | 2 |
JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | Census, Compendium | Yes | 1 | hippie | 136 | 59 | 5 | 5 | 5 |
JMJD6_ENST00000397625 | JMJD6 | Q6NYC1 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 133 | 21 | 21 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KDM3A_ENST00000312912 | KDM3A | Q9Y4C1 | Lysine-specific demethylase 3A | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 136 | 461 | 47 | 47 | 0 |
KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | Census, Compendium | Yes | 1 | hippie | 357 | 275 | 55 | 55 | 2 |
KIR2DL4_ENST00000357494 | KIR2DL4 | Q99706-4 | Isoform 4 of Killer cell immunoglobulin-like receptor 2DL4 | chr19 | Not Cancer Driver | No | 1 | intact | 43 | 166 | 16 | 16 | 0 |
KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | Census, Compendium | Yes | 1 | hippie | 226 | 83 | 33 | 33 | 21 |
KPNA1 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 3 | intact, hippie | 65 | 121 | 18 | 18 | 0 |
KPNA6 | KPNA6 | O60684 | Importin subunit alpha-7 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 70 | 97 | 17 | 17 | 0 |
LASP1 | LASP1 | Q14847 | LIM and SH3 domain protein 1 | chr17 | Census | Yes | 1 | hippie | 29 | 198 | 24 | 24 | 0 |
LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | Census | Yes | 1 | hippie | 86 | 94 | 13 | 13 | 1 |
LDHB_ENST00000350669 | LDHB | P07195 | L-lactate dehydrogenase B chain | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 15 | 2 | 2 | 11 |
LIMA1_ENST00000341247 | LIMA1 | Q9UHB6 | LIM domain and actin-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 88 | 687 | 81 | 81 | 0 |
LMO2_ENST00000395833 | LMO2 | P25791 | Rhombotin-2 | chr11 | Census | Yes | 1 | intact, hippie | 35 | 14 | 1 | 1 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LZTR1_ENST00000646124 | LZTR1 | Q8N653 | Leucine-zipper-like transcriptional regulator 1 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 160 | 106 | 18 | 18 | 26 |
MAGEA3 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | Not Cancer Driver | No | 1 | hippie | 79 | 103 | 18 | 18 | 0 |
MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 17 | 1 | 1 | 0 |
MAP7D1 | MAP7D1 | Q3KQU3 | MAP7 domain-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 99 | 817 | 90 | 90 | 0 |
MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 25 | 1 | 1 | 0 |
MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | Not Cancer Driver | No | 1 | hippie | 70 | 411 | 58 | 58 | 0 |
MBD1_ENST00000591416 | MBD1 | Q9UIS9 | Methyl-CpG-binding domain protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 115 | 322 | 49 | 49 | 0 |
MCM3_ENST00000229854 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 310 | 47 | 47 | 0 |
MCM5 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | Not Cancer Driver | No | 1 | hippie | 88 | 109 | 20 | 20 | 1 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 20 | 2 | 2 | 0 |
MFSD4A | MFSD4A | Q8N468 | Major facilitator superfamily domain-containing protein 4A | chr1 | Not Cancer Driver | No | 1 | hippie | 56 | 29 | 3 | 3 | 0 |
MLST8_ENST00000397124 | MLST8 | Q9BVC4 | Target of rapamycin complex subunit LST8 | chr16 | Not Cancer Driver | No | 1 | hippie | 37 | 45 | 3 | 3 | 0 |
MSN | MSN | P26038 | Moesin | chrX | Census, Compendium | Yes | 1 | hippie | 108 | 286 | 56 | 56 | 1 |
MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | Census, Compendium | Yes | 2 | intact, hippie | 379 | 296 | 37 | 37 | 18 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYH14_ENST00000596571 | MYH14 | Q7Z406 | Myosin-14 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 275 | 1215 | 169 | 169 | 5 |
MYL6B | MYL6B | P14649 | Myosin light chain 6B | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 109 | 14 | 14 | 0 |
MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 144 | 34 | 4 | 4 | 0 |
MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 66 | 11 | 11 | 0 |
MYO1D | MYO1D | O94832 | Unconventional myosin-Id | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 126 | 61 | 6 | 6 | 0 |
MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 176 | 342 | 41 | 41 | 3 |
NAA10 | NAA10 | P41227 | N-alpha-acetyltransferase 10 | chrX | Not Cancer Driver | No | 1 | hippie | 33 | 117 | 17 | 17 | 3 |
NAA15 | NAA15 | Q9BXJ9 | N-alpha-acetyltransferase 15, NatA auxiliary subunit | chr4 | Not Cancer Driver | No | 1 | hippie | 95 | 115 | 17 | 17 | 0 |
NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
NDUFS3 | NDUFS3 | O75489 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 26 | 3 | 3 | 2 |
NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | Compendium | Yes | 1 | hippie | 37 | 102 | 9 | 9 | 1 |
NMD3_ENST00000351193 | NMD3 | Q96D46 | 60S ribosomal export protein NMD3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 104 | 20 | 20 | 0 |
NMI | NMI | Q13287 | N-myc-interactor | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 104 | 12 | 12 | 0 |
NOMO1 | NOMO1 | Q15155 | Nodal modulator 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 130 | 128 | 23 | 23 | 0 |
NOMO2 | NOMO2 | Q5JPE7 | Nodal modulator 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 62 | 126 | 11 | 11 | 0 |
NPAS1_ENST00000449844 | NPAS1 | Q99742 | Neuronal PAS domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 309 | 23 | 23 | 0 |
NR1H2_ENST00000593926 | NR1H2 | P55055 | Oxysterols receptor LXR-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 56 | 179 | 30 | 30 | 0 |
NR1H3_ENST00000467728 | NR1H3 | Q13133 | Oxysterols receptor LXR-alpha | chr11 | Not Cancer Driver | No | 1 | hippie | 56 | 146 | 13 | 13 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NSF | NSF | P46459 | Vesicle-fusing ATPase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 84 | 3 | 3 | 2 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUDCD1 | NUDCD1 | Q96RS6 | NudC domain-containing protein 1 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 38 | 4 | 4 | 0 |
OTUD4_ENST00000447906 | OTUD4 | Q01804 | OTU domain-containing protein 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 148 | 788 | 120 | 120 | 0 |
OTULIN | OTULIN | Q96BN8 | Ubiquitin thioesterase otulin | chr5 | Not Cancer Driver | No | 1 | hippie | 47 | 97 | 5 | 5 | 2 |
PABPC3 | PABPC3 | Q9H361 | Polyadenylate-binding protein 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 154 | 286 | 68 | 68 | 0 |
PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | Compendium | Yes | 1 | hippie, biogrid | 89 | 242 | 49 | 49 | 0 |
PARP9 | PARP9 | Q8IXQ6 | Protein mono-ADP-ribosyltransferase PARP9 | chr3 | Not Cancer Driver | No | 1 | hippie | 110 | 45 | 3 | 3 | 0 |
PAWR | PAWR | Q96IZ0 | PRKC apoptosis WT1 regulator protein | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 327 | 33 | 33 | 0 |
PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | Census, Compendium | Yes | 2 | intact, hippie | 290 | 173 | 45 | 45 | 2 |
PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | Census, Compendium | Yes | 1 | hippie | 164 | 231 | 44 | 44 | 7 |
PFKL | PFKL | P17858 | ATP-dependent 6-phosphofructokinase, liver type | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 91 | 29 | 4 | 4 | 0 |
PGD | PGD | P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 19 | 3 | 3 | 0 |
PHGDH_ENST00000641023 | PHGDH | O43175 | D-3-phosphoglycerate dehydrogenase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 38 | 4 | 4 | 8 |
PIAS1_ENST00000249636 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | Not Cancer Driver | No | 1 | hippie | 80 | 241 | 43 | 43 | 0 |
PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | Census, Compendium | Yes | 1 | hippie | 1669 | 38 | 11 | 11 | 30 |
PLAUR | PLAUR | Q03405 | Urokinase plasminogen activator surface receptor | chr19 | Not Cancer Driver | No | 1 | hippie | 49 | 18 | 5 | 5 | 0 |
PLEC | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 677 | 2130 | 272 | 272 | 2 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 112 | 312 | 34 | 34 | 0 |
POR | POR | P16435 | NADPH--cytochrome P450 reductase | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 93 | 4 | 4 | 9 |
PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | Not Cancer Driver | No | 1 | hippie | 63 | 68 | 9 | 9 | 0 |
PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | Not Cancer Driver | No | 1 | hippie | 72 | 69 | 7 | 7 | 0 |
PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | Census | Yes | 1 | hippie | 72 | 44 | 4 | 4 | 3 |
PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | Census, Compendium | Yes | 1 | hippie | 205 | 148 | 40 | 40 | 0 |
PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | Compendium | Yes | 1 | hippie | 79 | 43 | 9 | 9 | 0 |
PRKCE | PRKCE | Q02156 | Protein kinase C epsilon type | chr2 | Not Cancer Driver | No | 1 | hippie | 107 | 170 | 26 | 26 | 0 |
PRKD3 | PRKD3 | O94806 | Serine/threonine-protein kinase D3 | chr2 | Not Cancer Driver | No | 1 | hippie | 125 | 183 | 20 | 20 | 0 |
PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 18 | 1 | 1 | 0 |
PRMT3 | PRMT3 | O60678 | Protein arginine N-methyltransferase 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 68 | 52 | 9 | 9 | 0 |
PRMT9 | PRMT9 | Q6P2P2 | Protein arginine N-methyltransferase 9 | chr4 | Not Cancer Driver | No | 1 | hippie | 84 | 63 | 4 | 4 | 0 |
PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 1 | hippie | 55 | 131 | 10 | 10 | 0 |
PTBP2_ENST00000426398 | PTBP2 | Q9UKA9 | Polypyrimidine tract-binding protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 84 | 136 | 20 | 20 | 0 |
PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | Not Cancer Driver | No | 3 | intact, hippie | 134 | 425 | 55 | 55 | 0 |
PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 3 | 0 | 0 | 0 |
PTPA_ENST00000337738 | PTPA | Q15257 | Serine/threonine-protein phosphatase 2A activator | chr9 | Not Cancer Driver | No | 1 | hippie | 40 | 63 | 2 | 2 | 0 |
PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | Census, Compendium | Yes | 2 | intact, hippie | 129 | 260 | 38 | 38 | 60 |
PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 57 | 120 | 14 | 14 | 0 |
PYGL | PYGL | P06737 | Glycogen phosphorylase, liver form | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 98 | 23 | 2 | 2 | 2 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | Census, Compendium | Yes | 1 | intact, hippie | 70 | 167 | 14 | 14 | 0 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 75 | 400 | 48 | 48 | 0 |
RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 76 | 7 | 7 | 0 |
RNF220_ENST00000361799 | RNF220 | Q5VTB9 | E3 ubiquitin-protein ligase RNF220 | chr1 | Not Cancer Driver | No | 1 | hippie | 104 | 401 | 75 | 75 | 0 |
RNF31 | RNF31 | Q96EP0 | E3 ubiquitin-protein ligase RNF31 | chr14 | Not Cancer Driver | No | 1 | hippie | 142 | 319 | 45 | 45 | 0 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
RPS6KA5 | RPS6KA5 | O75582 | Ribosomal protein S6 kinase alpha-5 | chr14 | Not Cancer Driver | No | 1 | hippie | 97 | 187 | 18 | 18 | 0 |
RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 226 | 26 | 26 | 0 |
RRP1B | RRP1B | Q14684 | Ribosomal RNA processing protein 1 homolog B | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 513 | 48 | 48 | 0 |
RTF1 | RTF1 | Q92541 | RNA polymerase-associated protein RTF1 homolog | chr15 | Not Cancer Driver | No | 1 | hippie | 83 | 568 | 67 | 67 | 0 |
RXRA | RXRA | P19793 | Retinoic acid receptor RXR-alpha | chr9 | Compendium | Yes | 1 | intact, hippie | 90 | 184 | 26 | 26 | 0 |
SEPT6 | SEPTIN6 | Q14141 | Septin-6 | chrX | Not Cancer Driver | No | 1 | intact | 69 | 161 | 25 | 25 | 0 |
SHANK1 | SHANK1 | Q9Y566 | SH3 and multiple ankyrin repeat domains protein 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 288 | 1659 | 186 | 186 | 0 |
SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 32 | 7 | 7 | 0 |
SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 58 | 5 | 5 | 1 |
SIRPA_ENST00000400068 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | Census, Compendium | Yes | 1 | hippie | 96 | 281 | 51 | 51 | 0 |
SLITRK5 | SLITRK5 | O94991 | SLIT and NTRK-like protein 5 | chr13 | Not Cancer Driver | No | 1 | hippie | 257 | 346 | 93 | 93 | 0 |
SMARCA2 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 273 | 1009 | 160 | 160 | 42 |
SMARCA4 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | Census, Compendium | Yes | 1 | hippie | 349 | 1072 | 195 | 195 | 5 |
SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | Not Cancer Driver | No | 1 | hippie | 89 | 256 | 31 | 31 | 0 |
SNX1_ENST00000559844 | SNX1 | Q13596 | Sorting nexin-1 | chr15 | Not Cancer Driver | No | 1 | hippie | 61 | 214 | 25 | 25 | 0 |
SNX2 | SNX2 | O60749 | Sorting nexin-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 45 | 218 | 18 | 18 | 0 |
SNX6 | SNX6 | Q9UNH7 | Sorting nexin-6 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 85 | 7 | 7 | 0 |
SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 84 | 297 | 46 | 46 | 0 |
SPACA1 | SPACA1 | Q9HBV2 | Sperm acrosome membrane-associated protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 79 | 9 | 9 | 0 |
SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 315 | 980 | 114 | 114 | 0 |
SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 311 | 869 | 123 | 123 | 0 |
SPTB_ENST00000389721 | SPTB | P11277 | Spectrin beta chain, erythrocytic | chr14 | Not Cancer Driver | No | 1 | hippie | 328 | 562 | 70 | 70 | 7 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie | 53 | 130 | 11 | 11 | 1 |
STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | Not Cancer Driver | No | 4 | intact, hippie | 131 | 144 | 25 | 25 | 26 |
STAT2 | STAT2 | P52630 | Signal transducer and activator of transcription 2 | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 90 | 178 | 22 | 22 | 2 |
STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | Census, Compendium | Yes | 3 | intact, hippie, biogrid | 110 | 152 | 15 | 15 | 19 |
STAT4_ENST00000358470 | STAT4 | Q14765 | Signal transducer and activator of transcription 4 | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 154 | 143 | 36 | 36 | 0 |
STAT5A_ENST00000590949 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 89 | 125 | 14 | 14 | 0 |
STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | Census, Compendium | Yes | 1 | hippie | 93 | 144 | 19 | 19 | 5 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
STK4 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 70 | 231 | 30 | 30 | 0 |
STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | Not Cancer Driver | No | 1 | hippie | 15 | 149 | 15 | 15 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SUMO4 | SUMO4 | Q6EEV6 | Small ubiquitin-related modifier 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 7 | 69 | 4 | 4 | 0 |
SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | Census | Yes | 1 | hippie | 96 | 131 | 27 | 27 | 5 |
TBCA_ENST00000380377 | TBCA | O75347 | Tubulin-specific chaperone A | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 30 | 1 | 1 | 0 |
TBCD | TBCD | Q9BTW9 | Tubulin-specific chaperone D | chr17 | Not Cancer Driver | No | 1 | hippie | 156 | 60 | 9 | 9 | 11 |
TES | TES | Q9UGI8 | Testin | chr7 | Not Cancer Driver | No | 1 | hippie | 56 | 100 | 7 | 7 | 0 |
TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 2 | 0 | 0 | 0 |
TEX264_ENST00000416589 | TEX264 | Q9Y6I9 | Testis-expressed protein 264 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 107 | 11 | 11 | 0 |
TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 41 | 4 | 4 | 10 |
TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | Census, Compendium | Yes | 1 | hippie | 106 | 60 | 16 | 16 | 25 |
TMOD3 | TMOD3 | Q9NYL9 | Tropomodulin-3 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 190 | 24 | 24 | 0 |
TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | Census, Compendium | Yes | 1 | hippie | 98 | 231 | 33 | 33 | 1 |
TNFRSF1A | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | Not Cancer Driver | No | 1 | hippie | 58 | 111 | 15 | 15 | 12 |
TNFRSF1B | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | Not Cancer Driver | No | 1 | hippie | 48 | 229 | 28 | 28 | 0 |
TNFSF13B | TNFSF13B | Q9Y275 | Tumor necrosis factor ligand superfamily member 13B | chr13 | Not Cancer Driver | No | 1 | intact | 41 | 91 | 15 | 15 | 0 |
TNK2_ENST00000333602 | TNK2 | Q07912 | Activated CDC42 kinase 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 137 | 593 | 81 | 81 | 0 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 227 | 1632 | 190 | 190 | 0 |
TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 234 | 29 | 29 | 8 |
TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | Not Cancer Driver | No | 1 | hippie | 26 | 74 | 5 | 5 | 0 |
TRIM11 | TRIM11 | Q96F44 | E3 ubiquitin-protein ligase TRIM11 | chr1 | Not Cancer Driver | No | 1 | hippie | 58 | 132 | 14 | 14 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TSNAX | TSNAX | Q99598 | Translin-associated protein X | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 68 | 3 | 3 | 0 |
TYK2 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | Not Cancer Driver | No | 1 | hippie | 148 | 213 | 29 | 29 | 0 |
U2AF2 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | Compendium | Yes | 1 | hippie | 78 | 191 | 28 | 28 | 0 |
UBD | UBD | O15205 | Ubiquitin D | chr6 | Not Cancer Driver | No | 1 | hippie | 31 | 8 | 1 | 1 | 0 |
UBE2F_ENST00000272930 | UBE2F | Q969M7 | NEDD8-conjugating enzyme UBE2F | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 19 | 5 | 5 | 0 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 32 | 6 | 6 | 0 |
UBXN6 | UBXN6 | Q9BZV1 | UBX domain-containing protein 6 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 132 | 26 | 26 | 0 |
UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 34 | 7 | 7 | 4 |
UNK | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 511 | 46 | 46 | 0 |
UQCRC1 | UQCRC1 | P31930 | Cytochrome b-c1 complex subunit 1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 57 | 55 | 6 | 6 | 2 |
USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | Not Cancer Driver | No | 1 | hippie | 121 | 224 | 42 | 42 | 0 |
USP2 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 88 | 213 | 39 | 39 | 0 |
USP22 | USP22 | Q9UPT9 | Ubiquitin carboxyl-terminal hydrolase 22 | chr17 | Not Cancer Driver | No | 1 | hippie | 64 | 50 | 1 | 1 | 0 |
USP39 | USP39 | Q53GS9 | U4/U6.U5 tri-snRNP-associated protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 58 | 128 | 10 | 10 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VDR_ENST00000549336 | VDR | P11473 | Vitamin D3 receptor | chr12 | Not Cancer Driver | No | 1 | hippie | 64 | 102 | 16 | 16 | 14 |
VPS26A_ENST00000263559 | VPS26A | O75436 | Vacuolar protein sorting-associated protein 26A | chr10 | Not Cancer Driver | No | 1 | hippie | 27 | 44 | 2 | 2 | 0 |
VPS29_ENST00000549578 | VPS29 | Q9UBQ0 | Vacuolar protein sorting-associated protein 29 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
WDR1 | WDR1 | O75083 | WD repeat-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 30 | 7 | 7 | 2 |
WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | Not Cancer Driver | No | 1 | hippie | 112 | 422 | 57 | 57 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
YAF2_ENST00000534854 | YAF2 | Q8IY57 | YY1-associated factor 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 27 | 166 | 27 | 27 | 0 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
ZC3H11B | ZC3H11B | A0A1B0GTU1 | Zinc finger CCCH domain-containing protein 11B | chr1 | Not Cancer Driver | No | 1 | hippie | 2 | 698 | 2 | 2 | 0 |
ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
ZNF467 | ZNF467 | Q7Z7K2 | Zinc finger protein 467 | chr7 | Not Cancer Driver | No | 1 | hippie | 75 | 345 | 37 | 37 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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