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SRSF4 ,SRSF4 ,Q08170
  • Uniprot Accession= Q08170
  • Ensembl Transcript= ENST00000373795.6
  • Uniprot Name= SRSF4
  • Name= Serine/arginine-rich splicing factor 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 163
  • Number of Interaction partner in hippie: 261
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 Not Cancer Driver No 1 hippie, biogrid 157 1294 155 155 0
AKAP17A AKAP17A Q02040 A-kinase anchor protein 17A chrX Not Cancer Driver No 1 hippie, biogrid 108 407 56 56 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 Not Cancer Driver No 1 hippie, biogrid 49 0 0 0 0
ARGLU1 ARGLU1 Q9NWB6 Arginine and glutamate-rich protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 37 246 33 33 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 Census Yes 1 hippie 96 384 49 49 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
BMS1 BMS1 Q14692 Ribosome biogenesis protein BMS1 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 179 708 88 88 1
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 34 149 10 10 0
BUD13 BUD13 Q9BRD0 BUD13 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 77 594 73 73 0
C17orf80_ENST00000535032 C17orf80 Q9BSJ5 Uncharacterized protein C17orf80 chr17 Not Cancer Driver No 1 hippie, biogrid 64 455 53 53 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CCDC86 CCDC86 Q9H6F5 Coiled-coil domain-containing protein 86 chr11 Not Cancer Driver No 1 hippie, biogrid 36 360 36 36 0
CCNL1 CCNL1 Q9UK58 Cyclin-L1 chr3 Not Cancer Driver No 1 hippie 58 281 38 38 0
CCNL2 CCNL2 Q96S94 Cyclin-L2 chr1 Not Cancer Driver No 1 hippie 77 251 33 33 0
CD2BP2 CD2BP2 O95400 CD2 antigen cytoplasmic tail-binding protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 49 259 40 40 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 hippie 100 618 77 77 0
CDK12 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 Census, Compendium Yes 1 hippie, biogrid 225 1202 160 160 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 Not Cancer Driver No 1 hippie, biogrid 155 1138 99 99 6
CENPO_ENST00000260662 CENPO Q9BU64 Centromere protein O chr2 Not Cancer Driver No 1 hippie, biogrid 23 54 5 5 0
CENPQ CENPQ Q7L2Z9 Centromere protein Q chr6 Not Cancer Driver No 1 hippie, biogrid 33 183 23 23 0
CHCHD1 CHCHD1 Q96BP2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 11 67 8 8 0
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 Not Cancer Driver No 1 hippie, biogrid 109 707 79 79 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 Not Cancer Driver No 1 hippie, biogrid 64 131 21 21 0
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 Not Cancer Driver No 1 hippie, biogrid 104 151 37 37 0
CLK3 CLK3 P49761 Dual specificity protein kinase CLK3 chr15 Not Cancer Driver No 1 hippie, biogrid 67 295 27 27 0
CLK4 CLK4 Q9HAZ1 Dual specificity protein kinase CLK4 chr5 Not Cancer Driver No 1 hippie, biogrid 60 102 14 14 0
CMTR1 CMTR1 Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 chr6 Not Cancer Driver No 1 hippie 81 176 20 20 0
CPSF4 CPSF4 O95639 Cleavage and polyadenylation specificity factor subunit 4 chr7 Not Cancer Driver No 1 hippie, biogrid 36 89 11 11 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie 55 398 52 52 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie, biogrid 151 481 83 83 1
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
DAP3_ENST00000343043 DAP3 P51398 28S ribosomal protein S29, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 58 82 14 14 0
DDX10 DDX10 Q13206 Probable ATP-dependent RNA helicase DDX10 chr11 Census Yes 1 hippie, biogrid 93 400 46 46 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 hippie, biogrid 72 342 30 30 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 Not Cancer Driver No 1 hippie, biogrid 121 426 71 71 0
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 Not Cancer Driver No 1 hippie, biogrid 86 452 40 40 0
DDX27 DDX27 Q96GQ7 Probable ATP-dependent RNA helicase DDX27 chr20 Not Cancer Driver No 1 hippie, biogrid 101 383 50 50 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 Not Cancer Driver No 1 hippie, biogrid 99 342 38 38 0
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 Not Cancer Driver No 1 hippie 82 180 26 26 1
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 1 hippie, biogrid 113 458 52 52 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DHX57 DHX57 Q6P158 Putative ATP-dependent RNA helicase DHX57 chr2 Not Cancer Driver No 1 hippie, biogrid 147 294 32 32 0
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 Not Cancer Driver No 1 hippie, biogrid 138 490 72 72 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX Not Cancer Driver No 1 hippie, biogrid 62 145 29 29 24
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EBNA1BP2_ENST00000236051 EBNA1BP2 Q99848 Probable rRNA-processing protein EBP2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 254 34 34 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 50 57 6 6 1
ENOX1 ENOX1 Q8TC92 Ecto-NOX disulfide-thiol exchanger 1 chr13 Not Cancer Driver No 1 hippie, biogrid 130 321 70 70 0
ENOX2 ENOX2 Q16206 Ecto-NOX disulfide-thiol exchanger 2 chrX Not Cancer Driver No 1 hippie, biogrid 103 239 41 41 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERAL1 ERAL1 O75616 GTPase Era, mitochondrial chr17 Not Cancer Driver No 1 hippie 32 81 6 6 1
ERGIC2 ERGIC2 Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 37 25 2 2 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FYTTD1 FYTTD1 Q96QD9 UAP56-interacting factor chr3 Not Cancer Driver No 1 hippie, biogrid 51 281 48 48 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 hippie, biogrid 64 299 29 29 3
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 Not Cancer Driver No 1 hippie, biogrid 87 201 27 27 0
GNL2 GNL2 Q13823 Nucleolar GTP-binding protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 87 446 51 51 0
GPATCH8 GPATCH8 Q9UKJ3 G patch domain-containing protein 8 chr17 Not Cancer Driver No 1 hippie, biogrid 210 1325 188 188 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 49 147 20 20 0
GZF1 GZF1 Q9H116 GDNF-inducible zinc finger protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 94 312 47 47 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 97 454 60 60 0
HBP1_ENST00000468410 HBP1 O60381 HMG box-containing protein 1 chr7 Not Cancer Driver No 1 hippie 48 263 16 16 0
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 718 971 150 150 1
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 70 290 58 58 4
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HP1BP3 HP1BP3 Q5SSJ5 Heterochromatin protein 1-binding protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 58 404 45 45 0
HTATSF1_ENST00000218364 HTATSF1 O43719 HIV Tat-specific factor 1 chrX Not Cancer Driver No 1 hippie 131 573 100 100 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
IMP4 IMP4 Q96G21 U3 small nucleolar ribonucleoprotein protein IMP4 chr2 Not Cancer Driver No 1 hippie, biogrid 49 57 8 8 0
JPH3 JPH3 Q8WXH2 Junctophilin-3 chr16 Not Cancer Driver No 1 hippie 130 534 92 92 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 hippie, biogrid 446 3145 338 338 0
KNOP1 KNOP1 Q1ED39 Lysine-rich nucleolar protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 44 402 39 39 0
KRR1 KRR1 Q13601 KRR1 small subunit processome component homolog chr12 Not Cancer Driver No 1 hippie, biogrid 37 194 23 23 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 136 726 100 100 0
LARP1B LARP1B Q659C4 La-related protein 1B chr4 Not Cancer Driver No 1 hippie, biogrid 91 651 70 70 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 2 hippie, biogrid 58 350 44 44 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 Census Yes 1 hippie 35 301 34 34 10
MAGOH MAGOH P61326 Protein mago nashi homolog chr1 Not Cancer Driver No 1 hippie 15 6 0 0 0
MAK16 MAK16 Q9BXY0 Protein MAK16 homolog chr8 Not Cancer Driver No 1 hippie, biogrid 41 130 19 19 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 76 446 42 42 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 hippie, biogrid 540 3169 529 529 0
MRPL1 MRPL1 Q9BYD6 39S ribosomal protein L1, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 44 46 5 5 0
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 25 12 1 1 0
MRPL15 MRPL15 Q9P015 39S ribosomal protein L15, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 32 81 3 3 0
MRPL16 MRPL16 Q9NX20 39S ribosomal protein L16, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 38 57 11 11 0
MRPL22 MRPL22 Q9NWU5 39S ribosomal protein L22, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 23 28 2 2 0
MRPL24_ENST00000368211 MRPL24 Q96A35 39S ribosomal protein L24, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 22 71 7 7 0
MRPL28_ENST00000389675 MRPL28 Q13084 39S ribosomal protein L28, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 21 52 3 3 0
MRPL32 MRPL32 Q9BYC8 39S ribosomal protein L32, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 35 91 15 15 0
MRPL40 MRPL40 Q9NQ50 39S ribosomal protein L40, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 20 104 9 9 0
MRPL47 MRPL47 Q9HD33 39S ribosomal protein L47, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 44 34 7 7 0
MRPL51 MRPL51 Q4U2R6 39S ribosomal protein L51, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
MRPL55_ENST00000366746 MRPL55 Q7Z7F7 39S ribosomal protein L55, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 19 67 13 13 0
MRPL9 MRPL9 Q9BYD2 39S ribosomal protein L9, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 24 54 3 3 0
MRPS10 MRPS10 P82664 28S ribosomal protein S10, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 19 22 3 3 0
MRPS30 MRPS30 Q9NP92 39S ribosomal protein S30, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 54 53 10 10 0
MRPS35 MRPS35 P82673 28S ribosomal protein S35, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 42 92 13 13 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 52 157 20 20 0
MRPS7 MRPS7 Q9Y2R9 28S ribosomal protein S7, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 31 26 0 0 1
MRRF MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 23 118 9 9 0
MTERF3 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 53 62 5 5 0
MTX2 MTX2 O75431 Metaxin-2 chr2 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 1 hippie, biogrid 109 142 18 18 0
NCBP3 NCBP3 Q53F19 Nuclear cap-binding protein subunit 3 chr17 Not Cancer Driver No 1 hippie 52 507 42 42 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NGRN NGRN Q9NPE2 Neugrin chr15 Not Cancer Driver No 1 hippie, biogrid 26 215 21 21 0
NKAPD1_ENST00000420986 NKAPD1 Q6ZUT1 Uncharacterized protein NKAPD1 chr11 Not Cancer Driver No 1 hippie 35 261 31 31 0
NKTR NKTR P30414 NK-tumor recognition protein chr3 Compendium Yes 1 hippie, biogrid 172 1299 153 153 0
NOC3L NOC3L Q8WTT2 Nucleolar complex protein 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 75 281 29 29 0
NOP16_ENST00000614830 NOP16 Q9Y3C1 Nucleolar protein 16 chr5 Not Cancer Driver No 1 hippie, biogrid 19 118 12 12 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NSA2 NSA2 O95478 Ribosome biogenesis protein NSA2 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 29 134 17 17 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NSUN4 NSUN4 Q96CB9 5-methylcytosine rRNA methyltransferase NSUN4 chr1 Not Cancer Driver No 1 hippie, biogrid 40 20 5 5 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PAK1IP1 PAK1IP1 Q9NWT1 p21-activated protein kinase-interacting protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 38 83 6 6 0
PATZ1 PATZ1 Q9HBE1 POZ-, AT hook-, and zinc finger-containing protein 1 chr22 Census Yes 1 hippie, biogrid 91 301 38 38 0
PAXBP1 PAXBP1 Q9Y5B6 PAX3- and PAX7-binding protein 1 chr21 Not Cancer Driver No 1 hippie, biogrid 96 532 55 55 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 120 461 39 39 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 Not Cancer Driver No 1 hippie 40 200 24 24 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 2 hippie, biogrid 94 700 90 90 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 Not Cancer Driver No 1 hippie 181 609 148 148 0
PPIE_ENST00000324379 PPIE Q9UNP9 Peptidyl-prolyl cis-trans isomerase E chr1 Not Cancer Driver No 1 hippie 51 102 17 17 0
PPIG_ENST00000448752 PPIG Q13427 Peptidyl-prolyl cis-trans isomerase G chr2 Not Cancer Driver No 1 hippie, biogrid 116 644 96 96 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
PRDM10_ENST00000528746 PRDM10 Q9NQV6 PR domain zinc finger protein 10 chr11 Not Cancer Driver No 1 hippie, biogrid 152 752 95 95 0
PRDM15 PRDM15 P57071 PR domain zinc finger protein 15 chr21 Not Cancer Driver No 1 hippie, biogrid 159 800 75 75 0
PRPF38A PRPF38A Q8NAV1 Pre-mRNA-splicing factor 38A chr1 Not Cancer Driver No 1 hippie 39 142 22 22 0
PRPF4B PRPF4B Q13523 Serine/threonine-protein kinase PRP4 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 120 646 86 86 0
PRRC2B PRRC2B Q5JSZ5 Protein PRRC2B chr9 Not Cancer Driver No 1 hippie 279 2199 278 278 0
PTCD1 PTCD1 O75127 Pentatricopeptide repeat-containing protein 1, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 99 224 42 42 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 hippie 73 192 25 25 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 Not Cancer Driver No 1 hippie, biogrid 22 188 10 10 6
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 174 291 99 99 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 Not Cancer Driver No 1 hippie, biogrid 229 1626 212 212 0
RBM19 RBM19 Q9Y4C8 Probable RNA-binding protein 19 chr12 Not Cancer Driver No 1 hippie, biogrid 146 514 76 76 0
RBM23 RBM23 Q86U06 Probable RNA-binding protein 23 chr14 Not Cancer Driver No 1 hippie, biogrid 46 207 25 25 0
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 hippie, biogrid 97 512 66 66 1
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM5 RBM5 P52756 RNA-binding protein 5 chr3 Not Cancer Driver No 1 hippie, biogrid 94 537 67 67 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX Not Cancer Driver No 1 hippie 82 380 81 81 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 Not Cancer Driver No 1 hippie, biogrid 77 371 75 75 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 Not Cancer Driver No 1 hippie, biogrid 34 298 26 26 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RIOX2_ENST00000394198 RIOX2 Q8IUF8 Ribosomal oxygenase 2 chr3 Not Cancer Driver No 1 hippie 49 74 10 10 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 2 hippie, biogrid 30 305 30 30 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 107 11 11 0
RPS10_ENST00000467531 RPS10 P46783 40S ribosomal protein S10 chr6 Not Cancer Driver No 1 hippie, biogrid 25 100 19 19 0
RPS13 RPS13 P62277 40S ribosomal protein S13 chr11 Not Cancer Driver No 1 hippie, biogrid 19 18 5 5 0
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 Not Cancer Driver No 1 hippie, biogrid 13 59 7 7 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 1 hippie, biogrid 16 14 1 1 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie, biogrid 15 61 3 3 23
RRP15 RRP15 Q9Y3B9 RRP15-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 50 278 48 48 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 Not Cancer Driver No 1 hippie, biogrid 66 270 44 44 0
RRS1 RRS1 Q15050 Ribosome biogenesis regulatory protein homolog chr8 Not Cancer Driver No 1 hippie, biogrid 23 315 18 18 0
RSBN1L RSBN1L Q6PCB5 Lysine-specific demethylase RSBN1L chr7 Not Cancer Driver No 1 hippie, biogrid 106 506 73 73 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 61 275 33 33 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 Not Cancer Driver No 1 hippie 71 685 63 63 0
SCAF1 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie, biogrid 135 1307 134 134 0
SF3A2 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie 30 382 21 21 0
SF3B2 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 hippie, biogrid 110 804 105 105 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 Census Yes 1 hippie, biogrid 59 595 48 48 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 58 285 40 40 1
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SON SON P18583 Protein SON chr21 Not Cancer Driver No 1 hippie, biogrid 234 2109 212 212 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SREK1_ENST00000380918 SREK1 Q8WXA9 Splicing regulatory glutamine/lysine-rich protein 1 chr5 Not Cancer Driver No 2 hippie, biogrid 60 438 53 53 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 78 343 46 46 0
SRPK3 SRPK3 Q9UPE1 SRSF protein kinase 3 chrX Not Cancer Driver No 1 hippie 63 217 30 30 0
SRRM1 SRRM1 Q8IYB3 Serine/arginine repetitive matrix protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 129 795 122 122 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 2 hippie, biogrid 433 2748 431 431 0
SRRM4 SRRM4 A7MD48 Serine/arginine repetitive matrix protein 4 chr12 Not Cancer Driver No 1 hippie 176 611 176 176 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 3 hippie, biogrid 41 198 34 34 0
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie 2 192 1 1 0
SRSF11 SRSF11 Q05519 Serine/arginine-rich splicing factor 11 chr1 Not Cancer Driver No 1 hippie, biogrid 63 362 55 55 0
SRSF12 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 Not Cancer Driver No 1 hippie, biogrid 36 205 31 31 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 Census, Compendium Yes 1 hippie 38 219 38 38 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie, biogrid 31 125 27 27 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 50 189 40 40 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 2 hippie, biogrid 69 259 49 49 0
SRSF8 SRSF8 Q9BRL6 Serine/arginine-rich splicing factor 8 chr11 Not Cancer Driver No 1 hippie, biogrid 23 282 23 23 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
THAP12 THAP12 O43422 52 kDa repressor of the inhibitor of the protein kinase chr11 Not Cancer Driver No 1 hippie 105 136 13 13 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie, biogrid 137 955 137 137 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 Not Cancer Driver No 1 hippie 92 443 66 66 1
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOE1 TOE1 Q96GM8 Target of EGR1 protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 44 210 22 22 10
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 Not Cancer Driver No 1 hippie, biogrid 149 795 105 105 0
TRA2A TRA2A Q13595 Transformer-2 protein homolog alpha chr7 Not Cancer Driver No 1 hippie, biogrid 45 253 41 41 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 Not Cancer Driver No 1 hippie 59 244 54 54 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 51 63 9 9 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 Not Cancer Driver No 1 hippie, biogrid 124 163 21 21 2
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
U2SURP U2SURP O15042 U2 snRNP-associated SURP motif-containing protein chr3 Not Cancer Driver No 1 hippie, biogrid 127 757 105 105 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
USP42 USP42 Q9H9J4 Ubiquitin carboxyl-terminal hydrolase 42 chr7 Not Cancer Driver No 1 hippie, biogrid 141 958 106 106 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 hippie 165 113 19 19 0
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 Not Cancer Driver No 1 hippie, biogrid 50 292 7 7 0
YBX2 YBX2 Q9Y2T7 Y-box-binding protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 48 342 46 46 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 137 597 117 117 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZBTB11 ZBTB11 O95625 Zinc finger and BTB domain-containing protein 11 chr3 Not Cancer Driver No 1 hippie, biogrid 116 417 39 39 2
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0
ZBTB24 ZBTB24 O43167 Zinc finger and BTB domain-containing protein 24 chr6 Not Cancer Driver No 1 hippie, biogrid 71 383 43 43 1
ZC3H10 ZC3H10 Q96K80 Zinc finger CCCH domain-containing protein 10 chr12 Not Cancer Driver No 1 hippie, biogrid 41 336 31 31 0
ZC3H14 ZC3H14 Q6PJT7 Zinc finger CCCH domain-containing protein 14 chr14 Not Cancer Driver No 1 hippie, biogrid 96 542 68 68 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 142 344 63 63 0
ZCRB1 ZCRB1 Q8TBF4 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 chr12 Compendium Yes 1 hippie, biogrid 29 100 13 13 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 84 49 9 9 0
ZFP62 ZFP62 Q8NB50 Zinc finger protein 62 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 43 245 8 8 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 Not Cancer Driver No 1 hippie 71 184 26 26 0
ZNF184_ENST00000377419 ZNF184 Q99676 Zinc finger protein 184 chr6 Not Cancer Driver No 1 hippie, biogrid 131 286 60 60 0
ZNF22 ZNF22 P17026 Zinc finger protein 22 chr10 Not Cancer Driver No 1 hippie, biogrid 26 112 15 15 0
ZNF354A ZNF354A O60765 Zinc finger protein 354A chr5 Not Cancer Driver No 1 hippie, biogrid 98 180 36 36 0
ZNF445_ENST00000425708 ZNF445 P59923 Zinc finger protein 445 chr3 Not Cancer Driver No 1 hippie, biogrid 136 398 61 61 0
ZNF48 ZNF48 Q96MX3 Zinc finger protein 48 chr16 Not Cancer Driver No 1 hippie, biogrid 87 516 78 78 0
ZNF512 ZNF512 Q96ME7 Zinc finger protein 512 chr2 Not Cancer Driver No 1 hippie, biogrid 76 280 42 42 0
ZNF574_ENST00000359044 ZNF574 Q6ZN55 Zinc finger protein 574 chr19 Not Cancer Driver No 1 hippie, biogrid 120 410 51 51 0
ZNF629 ZNF629 Q9UEG4 Zinc finger protein 629 chr16 Not Cancer Driver No 1 hippie, biogrid 78 479 36 36 0
ZNF638 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 1 hippie, biogrid 243 1667 209 209 0
ZNF646 ZNF646 O15015 Zinc finger protein 646 chr16 Not Cancer Driver No 1 hippie, biogrid 228 1410 173 173 0
ZNF689 ZNF689 Q96CS4 Zinc finger protein 689 chr16 Not Cancer Driver No 1 hippie, biogrid 63 169 15 15 0
ZNF70 ZNF70 Q9UC06 Zinc finger protein 70 chr22 Not Cancer Driver No 1 hippie, biogrid 66 182 25 25 0
ZNF768 ZNF768 Q9H5H4 Zinc finger protein 768 chr16 Not Cancer Driver No 1 hippie, biogrid 95 340 62 62 0
ZNF771 ZNF771 Q7L3S4 Zinc finger protein 771 chr16 Not Cancer Driver No 1 hippie, biogrid 5 160 5 5 0
ZNF777 ZNF777 Q9ULD5 Zinc finger protein 777 chr7 Not Cancer Driver No 1 hippie, biogrid 133 544 95 95 0
ZSCAN25 ZSCAN25 Q6NSZ9 Zinc finger and SCAN domain-containing protein 25 chr7 Not Cancer Driver No 1 hippie, biogrid 66 325 43 43 0