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SMPDL3B ,SMPDL3B ,Q92485
  • Uniprot Accession= Q92485
  • Ensembl Transcript= ENST00000373894.7
  • Uniprot Name= SMPDL3B
  • Name= Acid sphingomyelinase-like phosphodiesterase 3b
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 3
  • Number of Interaction partner in biogrid: 20
  • Number of Interaction partner in hippie: 35
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGK AGK Q53H12 Acylglycerol kinase, mitochondrial chr7 Not Cancer Driver No 1 hippie 71 77 6 6 0
C3orf14_ENST00000462069 C3orf14 Q9HBI5 Uncharacterized protein C3orf14 chr3 Not Cancer Driver No 1 hippie, biogrid 22 49 6 6 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 intact, hippie 30 2 0 0 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 Census, Compendium Yes 1 hippie, biogrid 39 94 17 17 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNL2 CCNL2 Q96S94 Cyclin-L2 chr1 Not Cancer Driver No 1 hippie, biogrid 77 251 33 33 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
CSRP3 CSRP3 P50461 Cysteine and glycine-rich protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 25 31 1 1 2
CST6 CST6 Q15828 Cystatin-M chr11 Not Cancer Driver No 1 hippie, biogrid 20 28 2 2 0
CYP2S1 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 75 46 10 10 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 hippie 87 373 36 36 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 Not Cancer Driver No 1 hippie, biogrid 55 27 2 2 11
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HOXB5 HOXB5 P09067 Homeobox protein Hox-B5 chr17 Not Cancer Driver No 1 hippie, biogrid 40 203 26 26 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact, hippie 190 280 57 57 64
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 149 534 114 114 0
LEAP2 LEAP2 Q969E1 Liver-expressed antimicrobial peptide 2 chr5 Not Cancer Driver No 1 hippie, biogrid 7 7 2 2 0
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 1 hippie, biogrid 12 46 3 3 0
NDUFS5_ENST00000372967 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 15 31 3 3 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 hippie 152 919 121 121 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 44 34 6 6 0
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 hippie, biogrid 115 71 13 13 7
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 113 23 6 6 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie, biogrid 79 137 12 12 0
TMEM185A TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie, biogrid 29 19 0 0 0
TUBD1_ENST00000592426 TUBD1 Q9UJT1 Tubulin delta chain chr17 Not Cancer Driver No 1 hippie, biogrid 54 3 0 0 0
YIPF3 YIPF3 Q9GZM5 Protein YIPF3 chr6 Not Cancer Driver No 1 hippie, biogrid 38 87 13 13 0
ZDHHC23 ZDHHC23 Q8IYP9 Palmitoyltransferase ZDHHC23 chr3 Not Cancer Driver No 1 hippie, biogrid 55 49 11 11 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZPBP2 ZPBP2 Q6X784 Zona pellucida-binding protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 47 7 1 1 0