Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
| ACAN | ACAN | P16112 | Aggrecan core protein | chr15 | Not Cancer Driver | No | 1 | hippie | 477 | 1868 | 323 | 323 | 2 |
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 32 | 1 | 1 | 10 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
| ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 70 | 14 | 14 | 2 |
| ADAM10 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 88 | 156 | 20 | 20 | 4 |
| APBB1 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 105 | 399 | 58 | 58 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
| ARHGEF11_ENST00000361409 | ARHGEF11 | O15085 | Rho guanine nucleotide exchange factor 11 | chr1 | Not Cancer Driver | No | 1 | hippie | 213 | 1036 | 138 | 138 | 0 |
| ARHGEF12 | ARHGEF12 | Q9NZN5 | Rho guanine nucleotide exchange factor 12 | chr11 | Census, Compendium | Yes | 1 | hippie | 212 | 972 | 150 | 150 | 0 |
| ARHGEF2 | ARHGEF2 | Q92974 | Rho guanine nucleotide exchange factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 146 | 450 | 70 | 70 | 0 |
| ARPC3 | ARPC3 | O15145 | Actin-related protein 2/3 complex subunit 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 26 | 6 | 6 | 0 |
| ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 23 | 5 | 5 | 2 |
| ATP6V0E1 | ATP6V0E1 | O15342 | V-type proton ATPase subunit e 1 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 11 | 0 | 0 | 0 | 0 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
| BSND | BSND | Q8WZ55 | Barttin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 209 | 36 | 36 | 4 |
| BTN2A1 | BTN2A1 | Q7KYR7 | Butyrophilin subfamily 2 member A1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 38 | 9 | 9 | 0 |
| C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 30 | 2 | 0 | 0 | 0 |
| CBR1 | CBR1 | P16152 | Carbonyl reductase [NADPH] 1 | chr21 | Not Cancer Driver | No | 1 | hippie | 27 | 62 | 11 | 11 | 0 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 0 | 0 | 0 | 0 |
| CD83 | CD83 | Q01151 | CD83 antigen | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 48 | 8 | 8 | 0 |
| CD9 | CD9 | P21926 | CD9 antigen | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 0 | 0 | 0 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
| CDH16 | CDH16 | O75309 | Cadherin-16 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 138 | 373 | 65 | 65 | 0 |
| CDKN2AIP | CDKN2AIP | Q9NXV6 | CDKN2A-interacting protein | chr4 | Not Cancer Driver | No | 1 | hippie | 53 | 352 | 38 | 38 | 0 |
| CEACAM21 | CEACAM21 | Q3KPI0 | Carcinoembryonic antigen-related cell adhesion molecule 21 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 51 | 73 | 14 | 14 | 0 |
| CLDND1_ENST00000510545 | CLDND1 | Q9NY35 | Claudin domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| CLEC4A | CLEC4A | Q9UMR7 | C-type lectin domain family 4 member A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 22 | 4 | 4 | 0 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 69 | 156 | 27 | 27 | 0 |
| CNR2 | CNR2 | P34972 | Cannabinoid receptor 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 21 | 4 | 4 | 0 |
| CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | Census, Compendium | Yes | 1 | hippie | 412 | 1796 | 247 | 247 | 33 |
| CSNK1G2 | CSNK1G2 | P78368 | Casein kinase I isoform gamma-2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 111 | 13 | 13 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
| CYYR1 | CYYR1 | Q96J86 | Cysteine and tyrosine-rich protein 1 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 24 | 12 | 12 | 0 |
| DEPDC1B | DEPDC1B | Q8WUY9 | DEP domain-containing protein 1B | chr5 | Not Cancer Driver | No | 1 | hippie | 76 | 52 | 6 | 6 | 0 |
| DIAPH1 | DIAPH1 | O60610 | Protein diaphanous homolog 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 118 | 692 | 57 | 57 | 1 |
| DLK1 | DLK1 | P80370 | Protein delta homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 0 | 0 | 0 | 0 |
| DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 145 | 24 | 24 | 1 |
| DNAAF5 | DNAAF5 | Q86Y56 | Dynein axonemal assembly factor 5 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 81 | 0 | 0 | 1 |
| DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | hippie | 23 | 46 | 6 | 6 | 1 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
| EDAR | EDAR | Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 116 | 20 | 20 | 18 |
| EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 100 | 14 | 14 | 0 |
| EEF1G | EEF1G | P26641 | Elongation factor 1-gamma | chr11 | Not Cancer Driver | No | 1 | hippie | 44 | 66 | 5 | 5 | 0 |
| EFNB1 | EFNB1 | P98172 | Ephrin-B1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 126 | 14 | 14 | 19 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| FAM171A2 | FAM171A2 | A8MVW0 | Protein FAM171A2 | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 478 | 4 | 4 | 0 |
| FCGRT_ENST00000426395 | FCGRT | P55899 | IgG receptor FcRn large subunit p51 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 65 | 12 | 12 | 0 |
| FFAR1 | FFAR1 | O14842 | Free fatty acid receptor 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 2 | 0 | 0 | 0 |
| FLNC | FLNC | Q14315 | Filamin-C | chr7 | Not Cancer Driver | No | 1 | hippie | 546 | 1442 | 288 | 288 | 7 |
| FRS2 | FRS2 | Q8WU20 | Fibroblast growth factor receptor substrate 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 69 | 415 | 58 | 58 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
| GALNT1 | GALNT1 | Q10472 | Polypeptide N-acetylgalactosaminyltransferase 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 67 | 14 | 14 | 0 |
| GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 24 | 3 | 3 | 0 |
| GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | Not Cancer Driver | No | 1 | hippie | 67 | 434 | 42 | 42 | 0 |
| GPC1 | GPC1 | P35052 | Glypican-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 58 | 166 | 14 | 14 | 0 |
| GPC4 | GPC4 | O75487 | Glypican-4 | chrX | Not Cancer Driver | No | 1 | hippie | 88 | 122 | 16 | 16 | 0 |
| GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 75 | 19 | 19 | 0 |
| GRK2 | GRK2 | P25098 | Beta-adrenergic receptor kinase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 77 | 87 | 8 | 8 | 0 |
| HACL1 | HACL1 | Q9UJ83 | 2-hydroxyacyl-CoA lyase 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 28 | 4 | 4 | 0 |
| HEPACAM2_ENST00000394468 | HEPACAM2 | A8MVW5 | HEPACAM family member 2 | chr7 | Not Cancer Driver | No | 3 | hippie, biogrid | 115 | 50 | 14 | 14 | 0 |
| HIST1H4A | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 15 | 31 | 5 | 5 | 0 |
| HIST1H4B | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 29 | 31 | 6 | 6 | 0 |
| HIST1H4C | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 29 | 31 | 7 | 7 | 0 |
| HIST1H4D | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 32 | 31 | 8 | 8 | 0 |
| HIST1H4E | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 45 | 31 | 14 | 14 | 0 |
| HIST1H4F | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 30 | 31 | 7 | 7 | 0 |
| HIST1H4H | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 22 | 31 | 9 | 9 | 0 |
| HIST1H4I | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 33 | 31 | 10 | 10 | 0 |
| HIST1H4J | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 26 | 31 | 9 | 9 | 0 |
| HIST1H4K | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 44 | 31 | 13 | 13 | 0 |
| HIST1H4L | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 25 | 31 | 14 | 14 | 0 |
| HIST4H4 | H4-16 | P62805 | Histone H4 | chr12 | Not Cancer Driver | No | 1 | intact | 21 | 31 | 7 | 7 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 106 | 257 | 37 | 37 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 200 | 13 | 13 | 0 |
| HSPA1L | HSPA1L | P34931 | Heat shock 70 kDa protein 1-like | chr6 | Not Cancer Driver | No | 1 | hippie | 119 | 141 | 28 | 28 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
| HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 283 | 26 | 26 | 2 |
| IFITM1_ENST00000528780 | IFITM1 | P13164 | Interferon-induced transmembrane protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 0 | 0 | 0 | 0 |
| IL13RA2_ENST00000243213 | IL13RA2 | Q14627 | Interleukin-13 receptor subunit alpha-2 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 69 | 0 | 0 | 0 | 0 |
| IL1RAP_ENST00000447382 | IL1RAP | Q9NPH3 | Interleukin-1 receptor accessory protein | chr3 | Not Cancer Driver | No | 1 | hippie | 79 | 50 | 11 | 11 | 0 |
| IL20RB | IL20RB | Q6UXL0 | Interleukin-20 receptor subunit beta | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 0 | 0 | 0 | 0 |
| IL22RA2 | IL22RA2 | Q969J5 | Interleukin-22 receptor subunit alpha-2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 14 | 3 | 3 | 0 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | Not Cancer Driver | No | 1 | hippie | 190 | 280 | 57 | 57 | 64 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 161 | 1072 | 133 | 133 | 2 |
| IRS2 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 69 | 1112 | 57 | 57 | 0 |
| IZUMO1 | IZUMO1 | Q8IYV9 | Izumo sperm-egg fusion protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 56 | 6 | 6 | 0 |
| JUP | JUP | P14923 | Junction plakoglobin | chr17 | Not Cancer Driver | No | 1 | hippie | 112 | 241 | 37 | 37 | 0 |
| KCNC3 | KCNC3 | Q14003 | Potassium voltage-gated channel subfamily C member 3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 405 | 29 | 29 | 4 |
| KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
| KCNE4 | KCNE4 | Q8WWG9 | Potassium voltage-gated channel subfamily E member 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 94 | 18 | 18 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LACTB | LACTB | P83111 | Serine beta-lactamase-like protein LACTB, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 44 | 121 | 3 | 3 | 0 |
| LAMTOR1 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 96 | 7 | 7 | 0 |
| LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | Census | Yes | 1 | hippie | 86 | 94 | 13 | 13 | 1 |
| LCN2_ENST00000277480 | LCN2 | P80188 | Neutrophil gelatinase-associated lipocalin | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 4 | 3 | 3 | 0 |
| LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie | 40 | 9 | 0 | 0 | 0 |
| LDHB_ENST00000350669 | LDHB | P07195 | L-lactate dehydrogenase B chain | chr12 | Not Cancer Driver | No | 1 | hippie | 47 | 15 | 2 | 2 | 11 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LRRIQ1 | LRRIQ1 | Q96JM4 | Leucine-rich repeat and IQ domain-containing protein 1 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 389 | 884 | 205 | 205 | 0 |
| LRTM1 | LRTM1 | Q9HBL6 | Leucine-rich repeat and transmembrane domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 100 | 69 | 25 | 25 | 0 |
| LTBR | LTBR | P36941 | Tumor necrosis factor receptor superfamily member 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 200 | 21 | 21 | 0 |
| MANSC1 | MANSC1 | Q9H8J5 | MANSC domain-containing protein 1 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 53 | 206 | 21 | 21 | 0 |
| MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | Census, Compendium | Yes | 1 | hippie, biogrid | 62 | 2 | 0 | 0 | 7 |
| MRAP2 | MRAP2 | Q96G30 | Melanocortin-2 receptor accessory protein 2 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 55 | 75 | 17 | 17 | 0 |
| NAA50 | NAA50 | Q9GZZ1 | N-alpha-acetyltransferase 50 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 14 | 1 | 1 | 0 |
| NCAN | NCAN | O14594 | Neurocan core protein | chr19 | Not Cancer Driver | No | 1 | hippie | 267 | 790 | 158 | 158 | 0 |
| NFKB1_ENST00000505458 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 104 | 344 | 38 | 38 | 0 |
| NID1 | NID1 | P14543 | Nidogen-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 246 | 340 | 72 | 72 | 0 |
| NPDC1 | NPDC1 | Q9NQX5 | Neural proliferation differentiation and control protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 253 | 20 | 20 | 0 |
| NPLOC4 | NPLOC4 | Q8TAT6 | Nuclear protein localization protein 4 homolog | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 47 | 8 | 8 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| NUDCD3 | NUDCD3 | Q8IVD9 | NudC domain-containing protein 3 | chr7 | Not Cancer Driver | No | 1 | hippie | 30 | 199 | 16 | 16 | 0 |
| OPALIN | OPALIN | Q96PE5 | Opalin | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 86 | 18 | 18 | 0 |
| OPTC | OPTC | Q9UBM4 | Opticin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 109 | 24 | 24 | 0 |
| PCDH12 | PCDH12 | Q9NPG4 | Protocadherin-12 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 158 | 582 | 80 | 80 | 0 |
| PCDHAC1 | PCDHAC1 | Q9H158 | Protocadherin alpha-C1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 255 | 386 | 92 | 92 | 0 |
| PCDHB16 | PCDHB16 | Q9NRJ7 | Protocadherin beta-16 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 214 | 247 | 70 | 70 | 0 |
| PCDHGB1 | PCDHGB1 | Q9Y5G3 | Protocadherin gamma-B1 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 220 | 329 | 61 | 61 | 0 |
| PFKM_ENST00000550924 | PFKM | P08237 | ATP-dependent 6-phosphofructokinase, muscle type | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 70 | 8 | 8 | 9 |
| PIANP | PIANP | Q8IYJ0 | PILR alpha-associated neural protein | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 45 | 217 | 38 | 38 | 0 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | Census | Yes | 1 | hippie, biogrid | 89 | 320 | 42 | 42 | 0 |
| PLEKHH1 | PLEKHH1 | Q9ULM0 | Pleckstrin homology domain-containing family H member 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 131 | 575 | 62 | 62 | 0 |
| PPFIA1 | PPFIA1 | Q13136 | Liprin-alpha-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 164 | 865 | 126 | 126 | 0 |
| PPFIA2 | PPFIA2 | O75334 | Liprin-alpha-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 342 | 936 | 263 | 263 | 0 |
| PPFIA3 | PPFIA3 | O75145 | Liprin-alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie | 140 | 831 | 107 | 107 | 0 |
| PPP2R5D | PPP2R5D | Q14738 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 178 | 13 | 13 | 4 |
| PPWD1 | PPWD1 | Q96BP3 | Peptidylprolyl isomerase domain and WD repeat-containing protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 180 | 10 | 10 | 0 |
| PROKR1 | PROKR1 | Q8TCW9 | Prokineticin receptor 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 0 | 0 | 0 | 0 |
| PRPF40A | PRPF40A | O75400 | Pre-mRNA-processing factor 40 homolog A | chr2 | Not Cancer Driver | No | 1 | hippie | 83 | 694 | 57 | 57 | 0 |
| PTGER3_ENST00000370931 | PTGER3 | P43115 | Prostaglandin E2 receptor EP3 subtype | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 17 | 2 | 2 | 0 |
| PTPRA_ENST00000399903 | PTPRA | P18433 | Receptor-type tyrosine-protein phosphatase alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 98 | 210 | 21 | 21 | 0 |
| PTPRD | PTPRD | P23468 | Receptor-type tyrosine-protein phosphatase delta | chr9 | Census, Compendium | Yes | 1 | hippie | 577 | 747 | 219 | 219 | 0 |
| PTPRF | PTPRF | P10586 | Receptor-type tyrosine-protein phosphatase F | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 268 | 696 | 96 | 96 | 0 |
| PTPRN2 | PTPRN2 | Q92932 | Receptor-type tyrosine-protein phosphatase N2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 274 | 580 | 169 | 169 | 0 |
| PTPRO | PTPRO | Q16827 | Receptor-type tyrosine-protein phosphatase O | chr12 | Not Cancer Driver | No | 1 | hippie | 204 | 137 | 34 | 34 | 0 |
| PTPRS | PTPRS | Q13332 | Receptor-type tyrosine-protein phosphatase S | chr19 | Not Cancer Driver | No | 1 | hippie | 250 | 829 | 111 | 111 | 0 |
| PTPRZ1 | PTPRZ1 | P23471 | Receptor-type tyrosine-protein phosphatase zeta | chr7 | Not Cancer Driver | No | 1 | hippie | 480 | 978 | 216 | 216 | 0 |
| RAB2A | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 58 | 4 | 4 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| RAP1GDS1_ENST00000408927 | RAP1GDS1 | P52306 | Rap1 GTPase-GDP dissociation stimulator 1 | chr4 | Census, Compendium | Yes | 1 | hippie | 93 | 13 | 0 | 0 | 0 |
| RELT | RELT | Q969Z4 | Tumor necrosis factor receptor superfamily member 19L | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 239 | 18 | 18 | 0 |
| RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | Census, Compendium | Yes | 1 | hippie | 208 | 105 | 12 | 12 | 139 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 19 | 2 | 2 | 0 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
| RND1 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 9 | 1 | 1 | 0 |
| RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
| RND3_ENST00000263895 | RND3 | P61587 | Rho-related GTP-binding protein RhoE | chr2 | Not Cancer Driver | No | 1 | hippie | 36 | 70 | 10 | 10 | 0 |
| RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 76 | 7 | 7 | 0 |
| RNF128 | RNF128 | Q8TEB7 | E3 ubiquitin-protein ligase RNF128 | chrX | Not Cancer Driver | No | 1 | hippie | 61 | 123 | 15 | 15 | 0 |
| RNF133 | RNF133 | Q8WVZ7 | E3 ubiquitin-protein ligase RNF133 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 60 | 5 | 5 | 0 |
| RNF149 | RNF149 | Q8NC42 | E3 ubiquitin-protein ligase RNF149 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 102 | 10 | 10 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| ROCK2 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 145 | 732 | 81 | 81 | 0 |
| RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 55 | 85 | 4 | 4 | 0 |
| SCN2B | SCN2B | O60939 | Sodium channel subunit beta-2 | chr11 | Not Cancer Driver | No | 3 | hippie, biogrid | 46 | 52 | 7 | 7 | 2 |
| SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
| SEMG1 | SEMG1 | P04279 | Semenogelin-1 | chr20 | Not Cancer Driver | No | 1 | hippie | 101 | 442 | 98 | 98 | 0 |
| SEMG2 | SEMG2 | Q02383 | Semenogelin-2 | chr20 | Not Cancer Driver | No | 1 | hippie | 147 | 561 | 145 | 145 | 0 |
| SEPHS1 | SEPHS1 | P49903 | Selenide, water dikinase 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 29 | 10 | 10 | 0 |
| SGCA | SGCA | Q16586 | Alpha-sarcoglycan | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 82 | 9 | 9 | 29 |
| SH2D3C | SH2D3C | Q8N5H7 | SH2 domain-containing protein 3C | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 440 | 72 | 72 | 0 |
| SHISAL1 | SHISAL1 | Q3SXP7 | Protein shisa-like-1 | chr22 | Not Cancer Driver | No | 1 | hippie | 47 | 52 | 20 | 20 | 0 |
| SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 356 | 32 | 32 | 0 |
| SOWAHC | SOWAHC | Q53LP3 | Ankyrin repeat domain-containing protein SOWAHC | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 382 | 18 | 18 | 0 |
| SUGT1 | SUGT1 | Q9Y2Z0 | Protein SGT1 homolog | chr13 | Not Cancer Driver | No | 1 | hippie | 31 | 119 | 5 | 5 | 0 |
| SYT11 | SYT11 | Q9BT88 | Synaptotagmin-11 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 105 | 23 | 23 | 0 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | Census, Compendium | Yes | 2 | hippie, biogrid | 106 | 60 | 16 | 16 | 25 |
| TIGIT | TIGIT | Q495A1 | T-cell immunoreceptor with Ig and ITIM domains | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 28 | 4 | 4 | 0 |
| TMEM150A | TMEM150A | Q86TG1 | Transmembrane protein 150A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 4 | 0 | 0 | 0 |
| TMEM171 | TMEM171 | Q8WVE6 | Transmembrane protein 171 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 150 | 18 | 18 | 0 |
| TMEM231 | TMEM231 | Q9H6L2 | Transmembrane protein 231 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 16 | 1 | 1 | 2 |
| TMEM30B | TMEM30B | Q3MIR4 | Cell cycle control protein 50B | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 17 | 0 | 0 | 0 |
| TMPRSS11B | TMPRSS11B | Q86T26 | Transmembrane protease serine 11B | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 5 | 0 | 0 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TRIO | TRIO | O75962 | Triple functional domain protein | chr5 | Not Cancer Driver | No | 1 | hippie | 400 | 1052 | 118 | 118 | 10 |
| TSPAN17_ENST00000515708 | TSPAN17 | Q96FV3 | Tetraspanin-17 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 0 | 0 | 0 | 0 |
| TTI1 | TTI1 | O43156 | TELO2-interacting protein 1 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 136 | 93 | 13 | 13 | 0 |
| TUBA1B | TUBA1B | P68363 | Tubulin alpha-1B chain | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 52 | 9 | 9 | 0 |
| TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 65 | 11 | 11 | 2 |
| UFD1 | UFD1 | Q92890 | Ubiquitin recognition factor in ER-associated degradation protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 26 | 100 | 7 | 7 | 0 |
| UNK | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 511 | 46 | 46 | 0 |
| VCAN | VCAN | P13611 | Versican core protein | chr5 | Not Cancer Driver | No | 1 | hippie | 647 | 2643 | 483 | 483 | 0 |
| VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
| WFDC2 | WFDC2 | Q14508 | WAP four-disulfide core domain protein 2 | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
| ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
| ZNF512B | ZNF512B | Q96KM6 | Zinc finger protein 512B | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 694 | 83 | 83 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|