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PTPN11_ENST00000351677 ,PTPN11 ,Q06124
  • Uniprot Accession= Q06124
  • Ensembl Transcript= ENST00000351677.6
  • Uniprot Name= PTPN11
  • Name= Tyrosine-protein phosphatase non-receptor type 11
  • Chromosome= chr12
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 144
  • Number of Interaction partner in biogrid: 46
  • Number of Interaction partner in hippie: 289
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact, hippie 108 912 75 75 0
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 intact 74 36 6 6 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 hippie 131 244 42 42 8
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie 58 108 10 10 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 intact 303 575 114 114 16
ANKRD26 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 Not Cancer Driver No 1 intact 224 1269 164 164 0
ANKRD39 ANKRD39 Q53RE8 Ankyrin repeat domain-containing protein 39 chr2 Not Cancer Driver No 1 hippie, biogrid 19 38 2 2 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 intact, hippie 59 61 12 12 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 49 20 4 4 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 Not Cancer Driver No 1 hippie 39 90 8 8 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 168 341 64 64 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCKDHA BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 Not Cancer Driver No 1 intact 53 121 18 18 11
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 Not Cancer Driver No 1 intact 47 23 3 3 5
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie 146 603 69 69 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 Not Cancer Driver No 1 hippie 81 0 0 0 0
BEX1 BEX1 Q9HBH7 Protein BEX1 chrX Not Cancer Driver No 1 intact, hippie 26 113 24 24 0
BEX2_ENST00000372677 BEX2 Q9BXY8 Protein BEX2 chrX Not Cancer Driver No 1 hippie 23 105 13 13 0
BLZF1 BLZF1 Q9H2G9 Golgin-45 chr1 Not Cancer Driver No 1 intact, hippie 51 218 24 24 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTLA BTLA Q7Z6A9 B- and T-lymphocyte attenuator chr3 Not Cancer Driver No 2 intact, hippie 31 57 5 5 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact 65 334 38 38 0
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 1 intact, hippie 70 176 18 18 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 intact, hippie 30 2 0 0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 Census Yes 1 hippie 160 562 104 104 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 1 intact 226 1481 173 173 0
CCKBR CCKBR P32239 Gastrin/cholecystokinin type B receptor chr11 Not Cancer Driver No 1 intact, hippie 122 61 22 22 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 hippie 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie 83 72 10 10 1
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 1 hippie 90 1 0 0 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie 59 36 6 6 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 hippie 41 36 2 2 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 Not Cancer Driver No 1 hippie 77 92 22 22 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 Not Cancer Driver No 1 intact, hippie 53 70 10 10 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 Not Cancer Driver No 2 intact, hippie 119 177 50 50 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 Not Cancer Driver No 1 hippie 82 52 11 11 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact 52 214 31 31 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact 39 23 2 2 1
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 2 intact, hippie 110 210 39 39 2
CDCA3 CDCA3 Q99618 Cell division cycle-associated protein 3 chr12 Not Cancer Driver No 1 intact 26 268 26 26 0
CDH5 CDH5 P33151 Cadherin-5 chr16 Not Cancer Driver No 1 hippie 144 305 55 55 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 Not Cancer Driver No 1 hippie 64 241 25 25 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
CHRAC1 CHRAC1 Q9NRG0 Chromatin accessibility complex protein 1 chr8 Not Cancer Driver No 1 hippie 10 35 8 8 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 Not Cancer Driver No 1 hippie 74 116 9 9 0
CLEC12A_ENST00000304361 CLEC12A Q5QGZ9 C-type lectin domain family 12 member A chr12 Not Cancer Driver No 1 hippie 41 9 3 3 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 Not Cancer Driver No 1 intact 36 71 2 2 0
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie 57 50 4 4 1
COL11A2_ENST00000341947 COL11A2 P13942 Collagen alpha-2(XI) chain chr6 Not Cancer Driver No 1 intact 286 1471 246 246 7
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 hippie 106 147 11 11 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 2 intact, hippie 38 160 25 25 0
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 Not Cancer Driver No 2 intact, hippie 204 541 120 120 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 Census, Compendium Yes 1 hippie 131 209 34 34 2
CSTB CSTB P04080 Cystatin-B chr21 Not Cancer Driver No 1 hippie, biogrid 7 40 0 0 1
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 Not Cancer Driver No 1 hippie 34 46 2 2 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 Not Cancer Driver No 1 hippie 37 3 0 0 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 2 intact, hippie 164 385 48 48 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 Census, Compendium Yes 1 hippie 62 5 1 1 0
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 81 17 2 2 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 Not Cancer Driver No 1 hippie 200 393 143 143 0
DAPP1 DAPP1 Q9UN19 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide chr4 Not Cancer Driver No 1 hippie, biogrid 50 40 9 9 0
DCAF7 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 1 hippie 48 0 0 0 0
DDI1 DDI1 Q8WTU0 Protein DDI1 homolog 1 chr11 Not Cancer Driver No 1 intact 151 166 73 73 0
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie 123 253 49 49 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact 53 190 32 32 1
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie, biogrid 33 198 17 17 3
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie 138 270 43 43 22
DOK1 DOK1 Q99704 Docking protein 1 chr2 Not Cancer Driver No 1 hippie 50 294 31 31 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 Not Cancer Driver No 1 intact 192 257 61 61 5
DST_ENST00000370788 DST Q03001-14 Isoform 9 of Dystonin chr6 Not Cancer Driver No 1 intact 729 1895 241 241 0
DUSP13_ENST00000472493 DUSP13 Q9UII6 Dual specificity protein phosphatase 13 isoform B chr10 Not Cancer Driver No 1 hippie 45 16 1 1 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 1 hippie 49 272 23 23 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact 109 100 14 14 0
EFHD2 EFHD2 Q96C19 EF-hand domain-containing protein D2 chr1 Not Cancer Driver No 1 hippie 13 101 1 1 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 2 hippie, biogrid 444 223 35 35 1
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 Not Cancer Driver No 1 intact 35 59 6 6 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact, hippie 147 211 38 38 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 171 187 39 39 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact 182 140 24 24 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 intact 280 71 15 15 0
EPOR EPOR P19235 Erythropoietin receptor chr19 Not Cancer Driver No 1 hippie 41 120 11 11 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 2 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 3 intact, hippie, biogrid 428 323 116 116 2
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 Not Cancer Driver No 1 intact 167 967 118 118 0
FAM71E1 GARIN5A Q6IPT2 Golgi associated RAB2 interactor protein 5A chr19 Not Cancer Driver No 1 intact 30 84 9 9 0
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie 291 309 42 42 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FCGR2A FCGR2A P12318 Low affinity immunoglobulin gamma Fc region receptor II-a chr1 Not Cancer Driver No 3 intact, hippie, biogrid 64 133 28 28 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 Census Yes 1 intact, hippie 51 99 30 30 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 Not Cancer Driver No 1 hippie 193 217 44 44 0
FGB FGB P02675 Fibrinogen beta chain chr4 Not Cancer Driver No 2 intact, hippie, biogrid 89 143 29 29 7
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 2 intact, hippie 152 230 43 43 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 2 intact, hippie 238 228 44 44 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact 173 241 26 26 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 2 intact, hippie 113 162 28 28 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 intact 56 20 3 3 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 Not Cancer Driver No 1 hippie 299 103 20 20 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 1 hippie 200 64 27 27 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 hippie 253 259 41 41 13
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 intact 124 327 70 70 3
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 3 intact, hippie 69 415 58 58 0
FRS3_ENST00000259748 FRS3 O43559 Fibroblast growth factor receptor substrate 3 chr6 Not Cancer Driver No 1 hippie 77 388 58 58 0
FSD1 FSD1 Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 chr19 Not Cancer Driver No 3 hippie, biogrid 66 90 17 17 0
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact 44 89 14 14 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 79 570 68 68 1
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GAB3_ENST00000369575 GAB3 Q8WWW8 GRB2-associated-binding protein 3 chrX Not Cancer Driver No 1 hippie 86 390 60 60 0
GAREM2 GAREM2 Q75VX8 GRB2-associated and regulator of MAPK protein 2 chr2 Not Cancer Driver No 1 hippie 29 502 15 15 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 Not Cancer Driver No 1 hippie 173 229 66 66 19
GMNN_ENST00000620958 GMNN O75496 Geminin chr6 Not Cancer Driver No 1 intact, hippie 24 206 24 24 1
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 54 10 0 0 15
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 115 854 96 96 0
GOLGA3_ENST00000450791 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 1 intact 221 1272 189 189 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 intact 55 287 31 31 0
GPX7 GPX7 Q96SL4 Glutathione peroxidase 7 chr1 Not Cancer Driver No 2 hippie, biogrid 24 6 1 1 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 11 intact, hippie, biogrid 28 10 1 1 0
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 hippie 413 426 147 147 11
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 intact 49 147 20 20 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie, biogrid 56 146 13 13 0
GTF2A2_ENST00000396063 GTF2A2 P52657 Transcription initiation factor IIA subunit 2 chr15 Not Cancer Driver No 1 hippie 8 8 0 0 0
GTF2E2 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 2 intact, hippie, biogrid 34 130 16 16 2
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 Not Cancer Driver No 1 intact 46 125 19 19 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HNRNPUL2 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 intact 71 418 35 35 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 Not Cancer Driver No 1 hippie 35 339 25 25 0
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 Not Cancer Driver No 1 intact 99 82 12 12 4
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie 94 268 35 35 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 Compendium Yes 1 hippie 55 50 6 6 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 Compendium Yes 1 hippie 55 175 22 22 10
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 Not Cancer Driver No 1 hippie 133 420 64 64 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 Census, Compendium Yes 1 hippie 102 315 40 40 2
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 Not Cancer Driver No 1 hippie 176 578 90 90 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 3 intact, hippie 190 280 57 57 64
IQCB1 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 Not Cancer Driver No 1 hippie 72 88 8 8 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 2 intact, hippie 161 1072 133 133 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 Not Cancer Driver No 1 hippie 69 1112 57 57 0
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie 297 798 203 203 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 124 66 5 5 30
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 Census, Compendium Yes 1 hippie 147 120 7 7 2
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 Not Cancer Driver No 1 intact 88 160 15 15 12
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 Not Cancer Driver No 1 hippie 68 73 19 19 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 Census, Compendium Yes 1 hippie 357 275 55 55 2
KIR2DL1 KIR2DL1 P43626 Killer cell immunoglobulin-like receptor 2DL1 chr19 Not Cancer Driver No 1 intact, hippie 112 135 44 44 0
KIR2DL3 KIR2DL3 P43628 Killer cell immunoglobulin-like receptor 2DL3 chr19 Not Cancer Driver No 1 intact, hippie 62 129 29 29 0
KIR2DL4_ENST00000357494 KIR2DL4 Q99706-4 Isoform 4 of Killer cell immunoglobulin-like receptor 2DL4 chr19 Not Cancer Driver No 1 hippie, biogrid 43 166 16 16 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 2 hippie, biogrid 226 83 33 33 21
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 Not Cancer Driver No 1 hippie 49 49 10 10 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 114 404 58 58 0
LAIR1 LAIR1 Q6GTX8 Leukocyte-associated immunoglobulin-like receptor 1 chr19 Not Cancer Driver No 1 hippie 65 179 43 43 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 hippie 74 611 69 69 0
LEPR LEPR P48357 Leptin receptor chr1 Not Cancer Driver No 1 hippie 243 57 11 11 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 15 133 6 6 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie, biogrid 54 65 16 16 0
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 Census, Compendium Yes 1 hippie 247 259 56 56 1
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 Not Cancer Driver No 1 hippie 162 277 115 115 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 intact, hippie 117 261 40 40 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 Not Cancer Driver No 1 hippie 664 317 52 52 1
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 131 18 2 2 1
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 1 hippie 289 261 33 33 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 Not Cancer Driver No 1 intact 103 301 30 30 0
LUM LUM P51884 Lumican chr12 Not Cancer Driver No 2 hippie, biogrid 108 1 0 0 0
LY9 LY9 Q9HBG7 T-lymphocyte surface antigen Ly-9 chr1 Not Cancer Driver No 1 hippie 141 249 49 49 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie, biogrid 94 96 24 24 6
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 Not Cancer Driver No 1 hippie 261 520 86 86 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 12 46 3 3 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 3 intact, hippie, biogrid 226 62 15 15 19
MPIG6B MPIG6B O95866 Megakaryocyte and platelet inhibitory receptor G6b chr6 Not Cancer Driver No 1 intact, hippie 37 61 7 7 0
MPL MPL P40238 Thrombopoietin receptor chr1 Census Yes 1 hippie 77 129 19 19 14
MPZL1 MPZL1 O95297 Myelin protein zero-like protein 1 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 36 56 7 7 0
MRPL42 MRPL42 Q9Y6G3 39S ribosomal protein L42, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 18 52 5 5 0
MRPL4_ENST00000307422 MRPL4 Q9BYD3 39S ribosomal protein L4, mitochondrial chr19 Not Cancer Driver No 1 intact 29 105 14 14 0
MRPS30 MRPS30 Q9NP92 39S ribosomal protein S30, mitochondrial chr5 Not Cancer Driver No 1 intact 54 53 10 10 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 intact 52 157 20 20 0
MRPS6 MRPS6 P82932 28S ribosomal protein S6, mitochondrial chr21 Not Cancer Driver No 1 intact 17 13 1 1 0
MRPS9 MRPS9 P82933 28S ribosomal protein S9, mitochondrial chr2 Not Cancer Driver No 1 intact 49 75 9 9 0
MS4A2 MS4A2 Q01362 High affinity immunoglobulin epsilon receptor subunit beta chr11 Not Cancer Driver No 1 hippie 64 19 8 8 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 2 hippie, biogrid 11 11 3 3 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 Not Cancer Driver No 1 hippie 62 582 49 49 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 Not Cancer Driver No 1 hippie, biogrid 67 232 38 38 0
MVP MVP Q14764 Major vault protein chr16 Not Cancer Driver No 1 hippie 141 285 31 31 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 intact 176 342 41 41 3
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NAA50 NAA50 Q9GZZ1 N-alpha-acetyltransferase 50 chr3 Not Cancer Driver No 1 intact 14 14 1 1 0
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 intact 34 26 3 3 2
NEB_ENST00000172853 NEB P20929 Nebulin chr2 Not Cancer Driver No 1 intact, hippie 1188 1984 355 355 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 Not Cancer Driver No 1 hippie 106 516 72 72 0
NOSIP NOSIP Q9Y314 Nitric oxide synthase-interacting protein chr19 Not Cancer Driver No 2 hippie, biogrid 37 159 21 21 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 intact 282 630 77 77 1
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 Not Cancer Driver No 1 hippie 123 0 0 0 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 Not Cancer Driver No 1 intact 112 221 21 21 1
NSUN5_ENST00000252594 NSUN5 Q96P11 28S rRNA (cytosine-C(5))-methyltransferase chr7 Not Cancer Driver No 1 intact, hippie 52 47 7 7 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 2 intact, hippie 168 57 8 8 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 Not Cancer Driver No 1 hippie 155 117 18 18 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 2 intact 249 57 21 21 0
NUDCD3 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 intact 30 199 16 16 0
NXT2_ENST00000372106 NXT2 Q9NPJ8 NTF2-related export protein 2 chrX Not Cancer Driver No 2 intact, hippie, biogrid 12 0 0 0 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 Not Cancer Driver No 1 intact, hippie 22 9 1 1 0
OVCA2 OVCA2 Q8WZ82 Esterase OVCA2 chr17 Not Cancer Driver No 3 hippie, biogrid 12 34 0 0 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 Not Cancer Driver No 1 hippie 80 39 5 5 11
PABPN1 PABPN1 Q86U42 Polyadenylate-binding protein 2 chr14 Not Cancer Driver No 1 intact 27 241 18 18 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 2 intact, hippie 77 378 56 56 0
PCDH7_ENST00000361762 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 intact 167 550 76 76 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 56 141 37 37 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 intact 85 272 22 22 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 2 intact, hippie 290 173 45 45 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 2 153 2 2 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 Not Cancer Driver No 1 hippie 318 121 39 39 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 2 intact, hippie 154 268 61 61 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 2 intact, hippie 96 418 47 47 3
PILRA PILRA Q9UKJ1 Paired immunoglobulin-like type 2 receptor alpha chr7 Not Cancer Driver No 1 hippie 44 133 21 21 0
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 Not Cancer Driver No 1 hippie 29 26 3 3 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 1 intact 176 434 98 98 8
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHM3 PLEKHM3 Q6ZWE6 Pleckstrin homology domain-containing family M member 3 chr2 Not Cancer Driver No 1 intact 96 169 16 16 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
PNCK_ENST00000370150 PNCK Q6P2M8 Calcium/calmodulin-dependent protein kinase type 1B chrX Not Cancer Driver No 1 intact, hippie 55 30 4 4 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 Census Yes 1 intact, hippie 59 181 45 45 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 19 43 4 4 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 Not Cancer Driver No 1 hippie 89 92 13 13 0
PRLR PRLR P16471 Prolactin receptor chr5 Not Cancer Driver No 1 hippie 154 282 70 70 2
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 hippie 71 109 16 16 0
PSMA4_ENST00000559082 PSMA4 P25789 Proteasome subunit alpha type-4 chr15 Not Cancer Driver No 1 hippie 29 28 9 9 0
PSMA6 PSMA6 P60900 Proteasome subunit alpha type-6 chr14 Not Cancer Driver No 1 hippie 37 2 1 1 0
PSMB1 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie 25 14 2 2 0
PSMB4 PSMB4 P28070 Proteasome subunit beta type-4 chr1 Not Cancer Driver No 1 hippie 23 18 2 2 0
PSMC3_ENST00000298852 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 1 hippie 55 131 10 10 0
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 Not Cancer Driver No 1 hippie 49 69 8 8 0
PSMD12 PSMD12 O00232 26S proteasome non-ATPase regulatory subunit 12 chr17 Not Cancer Driver No 1 hippie 48 24 3 3 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 Not Cancer Driver No 1 hippie 161 261 37 37 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 2 intact, hippie 134 425 55 55 0
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 Not Cancer Driver No 1 hippie 153 359 58 58 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie 129 260 38 38 60
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 intact 299 1231 149 149 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 hippie 73 192 25 25 0
PVR PVR P15151 Poliovirus receptor chr19 Not Cancer Driver No 1 hippie 39 120 19 19 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 4 intact, hippie 62 341 24 24 0
PYCR2 PYCR2 Q96C36 Pyrroline-5-carboxylate reductase 2 chr1 Not Cancer Driver No 1 intact 31 41 3 3 2
RAB1B RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 Not Cancer Driver No 1 intact 24 40 3 3 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 Not Cancer Driver No 1 intact, hippie 10 42 5 5 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 hippie 208 105 12 12 139
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie 203 299 71 71 5
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 Census Yes 1 hippie 498 191 55 55 0
RPIA RPIA P49247 Ribose-5-phosphate isomerase chr2 Not Cancer Driver No 1 hippie 37 97 4 4 1
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 Not Cancer Driver No 1 hippie 83 568 67 67 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 Not Cancer Driver No 1 intact 55 85 4 4 0
SAFB2 SAFB2 Q14151 Scaffold attachment factor B2 chr19 Not Cancer Driver No 1 intact 97 931 88 88 0
SAFB_ENST00000292123 SAFB Q15424 Scaffold attachment factor B1 chr19 Not Cancer Driver No 1 intact 111 911 110 110 0
SELE SELE P16581 E-selectin chr1 Not Cancer Driver No 1 intact, hippie 137 12 0 0 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 53 408 53 53 0
SERF2_ENST00000381359 SERF2 P84101 Small EDRK-rich factor 2 chr15 Not Cancer Driver No 1 hippie 11 59 11 11 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 Not Cancer Driver No 1 intact, hippie 51 57 5 5 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact 31 29 1 1 0
SGCG SGCG Q13326 Gamma-sarcoglycan chr13 Not Cancer Driver No 1 intact, hippie 64 60 12 12 4
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 2 intact, hippie 84 397 58 58 0
SHC4 SHC4 Q6S5L8 SHC-transforming protein 4 chr15 Not Cancer Driver No 1 hippie 74 325 44 44 0
SIGLEC11 SIGLEC11 Q96RL6 Sialic acid-binding Ig-like lectin 11 chr19 Not Cancer Driver No 1 hippie 123 267 42 42 0
SIGLEC12 SIGLEC12 Q96PQ1 Sialic acid-binding Ig-like lectin 12 chr19 Not Cancer Driver No 1 hippie 150 213 56 56 0
SIGLEC5 SIGLEC5 O15389 Sialic acid-binding Ig-like lectin 5 chr19 Not Cancer Driver No 2 hippie, biogrid 113 180 42 42 0
SIGLEC7 SIGLEC7 Q9Y286 Sialic acid-binding Ig-like lectin 7 chr19 Not Cancer Driver No 1 hippie 112 167 44 44 0
SIGLEC9_ENST00000250360 SIGLEC9 Q9Y336 Sialic acid-binding Ig-like lectin 9 chr19 Not Cancer Driver No 1 hippie 110 169 40 40 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 2 hippie, biogrid 96 281 51 51 0
SIT1 SIT1 Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 chr9 Not Cancer Driver No 1 intact, hippie 21 122 9 9 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 Not Cancer Driver No 2 intact, hippie 82 64 10 10 0
SLAMF6 SLAMF6 Q96DU3 SLAM family member 6 chr1 Not Cancer Driver No 1 hippie 69 60 14 14 0
SLC38A1_ENST00000546893 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid transporter 1 chr12 Not Cancer Driver No 1 intact, hippie 95 25 4 4 0
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 Not Cancer Driver No 1 intact, hippie 153 130 23 23 39
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 Not Cancer Driver No 1 intact 19 318 16 16 4
SLN_ENST00000525934 SLN O00631 Sarcolipin chr11 Not Cancer Driver No 1 intact, hippie 8 0 0 0 0
SNRNP27 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 2 intact, hippie, biogrid 20 155 20 20 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 hippie 22 66 3 3 2
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 Not Cancer Driver No 1 hippie 27 111 14 14 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 Compendium Yes 2 intact, hippie 197 458 62 62 38
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 Not Cancer Driver No 1 intact, hippie 46 168 26 26 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 hippie 46 169 29 29 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie 2 192 1 1 0
SRSF9 SRSF9 Q13242 Serine/arginine-rich splicing factor 9 chr12 Not Cancer Driver No 1 intact 20 111 8 8 0
SSRP1 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 1 intact 92 308 35 35 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 51 139 16 16 6
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 2 intact, hippie 131 144 25 25 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 1 hippie 89 125 14 14 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 Census, Compendium Yes 1 hippie 93 144 19 19 5
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact 83 35 10 10 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX Not Cancer Driver No 1 intact 31 221 22 22 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
SYT6_ENST00000610222 SYT6 Q5T7P8 Synaptotagmin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 98 137 18 18 0
TCEAL1_ENST00000372626 TCEAL1 Q15170 Transcription elongation factor A protein-like 1 chrX Not Cancer Driver No 3 intact, hippie, biogrid 18 147 18 18 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 2 intact, hippie, biogrid 41 0 0 0 1
TEK TEK Q02763 Angiopoietin-1 receptor chr9 Not Cancer Driver No 2 intact, hippie 219 126 22 22 10
THEMIS_ENST00000368250 THEMIS Q8N1K5 Protein THEMIS chr6 Not Cancer Driver No 3 intact, hippie, biogrid 208 111 34 34 0
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 Not Cancer Driver No 1 hippie 200 223 46 46 0
TLK1 TLK1 Q9UKI8 Serine/threonine-protein kinase tousled-like 1 chr2 Not Cancer Driver No 1 hippie 103 388 53 53 0
TMEM220 TMEM220 Q6QAJ8 Transmembrane protein 220 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 14 0 0 0 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 58 111 15 15 12
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 intact 18 83 9 9 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TREML1 TREML1 Q86YW5 Trem-like transcript 1 protein chr6 Not Cancer Driver No 1 hippie 35 136 19 19 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie 82 87 10 10 3
TRMT2B_ENST00000545398 TRMT2B Q96GJ1 tRNA (uracil-5-)-methyltransferase homolog B chrX Not Cancer Driver No 1 intact, hippie 75 31 2 2 0
TSC2 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 hippie 192 563 50 50 53
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 61 77 14 14 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 hippie 148 213 29 29 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 Not Cancer Driver No 1 hippie 137 425 39 39 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 intact 339 405 51 51 1
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 hippie 25 7 1 1 0
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 intact 166 105 13 13 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 Not Cancer Driver No 1 intact 62 109 9 9 3
ZNF326 ZNF326 Q5BKZ1 DBIRD complex subunit ZNF326 chr1 Not Cancer Driver No 1 intact 64 490 53 53 0