Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 6 | 2 | 2 | 0 |
ACTR3 | ACTR3 | P61158 | Actin-related protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 32 | 16 | 2 | 2 | 0 |
ACVR1B_ENST00000257963 | ACVR1B | P36896 | Activin receptor type-1B | chr12 | Census | Yes | 1 | hippie | 114 | 0 | 0 | 0 | 0 |
AKAP11 | AKAP11 | Q9UKA4 | A-kinase anchor protein 11 | chr13 | Not Cancer Driver | No | 4 | hippie, biogrid | 196 | 922 | 91 | 91 | 0 |
AKAP14 | AKAP14 | Q86UN6 | A-kinase anchor protein 14 | chrX | Not Cancer Driver | No | 3 | hippie, biogrid | 34 | 33 | 2 | 2 | 0 |
AKAP1_ENST00000539273 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 107 | 537 | 67 | 67 | 0 |
AKAP2_ENST00000259318 | AKAP2 | Q9Y2D5 | A-kinase anchor protein 2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 137 | 852 | 134 | 134 | 0 |
AKAP5_ENST00000320636 | AKAP5 | P24588 | A-kinase anchor protein 5 | chr14 | Not Cancer Driver | No | 4 | hippie, biogrid | 37 | 405 | 34 | 34 | 0 |
AKAP7 | AKAP7 | Q9P0M2 | A-kinase anchor protein 7 isoform gamma | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 38 | 122 | 18 | 18 | 0 |
AKAP9 | AKAP9 | Q99996 | A-kinase anchor protein 9 | chr7 | Census | Yes | 4 | hippie, biogrid | 474 | 2281 | 268 | 268 | 1 |
ANKRD36C | ANKRD36C | Q5JPF3 | Ankyrin repeat domain-containing protein 36C | chr2 | Not Cancer Driver | No | 1 | hippie | 197 | 1143 | 158 | 158 | 0 |
AP2M1_ENST00000292807 | AP2M1 | Q96CW1 | AP-2 complex subunit mu | chr3 | Not Cancer Driver | No | 3 | hippie, biogrid | 55 | 41 | 9 | 9 | 1 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 128 | 418 | 71 | 71 | 17 |
APPBP2 | APPBP2 | Q92624 | Amyloid protein-binding protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 61 | 10 | 0 | 0 | 0 |
ARF1_ENST00000272102 | ARF1 | P84077 | ADP-ribosylation factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 4 | 2 | 2 | 2 |
ARFGAP1_ENST00000370283 | ARFGAP1 | Q8N6T3 | ADP-ribosylation factor GTPase-activating protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 60 | 264 | 37 | 37 | 0 |
ARHGAP36 | ARHGAP36 | Q6ZRI8 | Rho GTPase-activating protein 36 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 194 | 132 | 61 | 61 | 0 |
ARMCX4 | ARMCX4 | Q5H9R4 | Armadillo repeat-containing X-linked protein 4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 1902 | 9 | 9 | 0 |
ARPC1B_ENST00000431816 | ARPC1B | O15143 | Actin-related protein 2/3 complex subunit 1B | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 34 | 1 | 1 | 0 |
ARPC2_ENST00000315717 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 40 | 49 | 8 | 8 | 0 |
ARPC4_ENST00000397261 | ARPC4 | P59998 | Actin-related protein 2/3 complex subunit 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 11 | 3 | 0 | 0 | 0 |
ATAD3A | ATAD3A | Q9NVI7 | ATPase family AAA domain-containing protein 3A | chr1 | Not Cancer Driver | No | 1 | hippie | 66 | 269 | 24 | 24 | 2 |
ATP5F1C | ATP5F1C | P36542 | ATP synthase subunit gamma, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 39 | 11 | 0 | 0 | 0 |
ATXN2L_ENST00000336783 | ATXN2L | Q8WWM7 | Ataxin-2-like protein | chr16 | Not Cancer Driver | No | 1 | hippie | 135 | 1000 | 131 | 131 | 0 |
AVPI1 | AVPI1 | Q5T686 | Arginine vasopressin-induced protein 1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 115 | 14 | 14 | 0 |
BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | Not Cancer Driver | No | 1 | hippie | 14 | 163 | 14 | 14 | 0 |
BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 17 | 112 | 9 | 9 | 0 |
BMP1 | BMP1 | P13497 | Bone morphogenetic protein 1 | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 119 | 154 | 25 | 25 | 3 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 14 | 103 | 6 | 6 | 2 |
C2orf88_ENST00000443551 | C2orf88 | Q9BSF0 | Small membrane A-kinase anchor protein | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 13 | 52 | 6 | 6 | 0 |
CAD | CAD | P27708 | CAD protein | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 368 | 52 | 52 | 1 |
CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 19 | 115 | 15 | 15 | 7 |
CALU_ENST00000249364 | CALU | O43852 | Calumenin | chr7 | Not Cancer Driver | No | 1 | hippie | 34 | 130 | 12 | 12 | 0 |
CAVIN1 | CAVIN1 | Q6NZI2 | Caveolae-associated protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 66 | 280 | 50 | 50 | 0 |
CBFB_ENST00000290858 | CBFB | Q13951 | Core-binding factor subunit beta | chr16 | Census, Compendium | Yes | 1 | hippie | 39 | 94 | 17 | 17 | 0 |
CCDC96 | CCDC96 | Q2M329 | Coiled-coil domain-containing protein 96 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 308 | 41 | 41 | 0 |
CCNL2 | CCNL2 | Q96S94 | Cyclin-L2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 251 | 33 | 33 | 0 |
CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 46 | 3 | 3 | 0 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 71 | 95 | 12 | 12 | 0 |
CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 92 | 2 | 2 | 0 |
CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 1 | hippie | 83 | 72 | 10 | 10 | 1 |
CCT6A | CCT6A | P40227 | T-complex protein 1 subunit zeta | chr7 | Not Cancer Driver | No | 1 | hippie | 66 | 5 | 1 | 1 | 0 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 36 | 6 | 6 | 0 |
CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | Not Cancer Driver | No | 1 | hippie | 41 | 36 | 2 | 2 | 0 |
CDC37 | CDC37 | Q16543 | Hsp90 co-chaperone Cdc37 | chr19 | Not Cancer Driver | No | 2 | intact, hippie | 52 | 214 | 31 | 31 | 0 |
CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | Not Cancer Driver | No | 1 | hippie | 48 | 5 | 1 | 1 | 0 |
CDK5RAP2 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 217 | 1136 | 128 | 128 | 0 |
CDKN2AIP | CDKN2AIP | Q9NXV6 | CDKN2A-interacting protein | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 352 | 38 | 38 | 0 |
CEP170 | CEP170 | Q5SW79 | Centrosomal protein of 170 kDa | chr1 | Not Cancer Driver | No | 1 | hippie | 264 | 1429 | 246 | 246 | 0 |
CEP57 | CEP57 | Q86XR8 | Centrosomal protein of 57 kDa | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 403 | 50 | 50 | 0 |
CORO1A | CORO1A | P31146 | Coronin-1A | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 126 | 15 | 15 | 1 |
CREB3L3 | CREB3L3 | Q68CJ9 | Cyclic AMP-responsive element-binding protein 3-like protein 3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 338 | 67 | 67 | 1 |
CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 71 | 75 | 8 | 8 | 4 |
DCAF7 | DCAF7 | P61962 | DDB1- and CUL4-associated factor 7 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 0 | 0 | 0 | 0 |
DCD_ENST00000293371 | DCD | P81605 | Dermcidin | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 67 | 19 | 19 | 0 |
DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 76 | 277 | 26 | 26 | 3 |
DDX11 | DDX11 | Q96FC9 | ATP-dependent DNA helicase DDX11 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 280 | 55 | 55 | 1 |
DDX39A | DDX39A | O00148 | ATP-dependent RNA helicase DDX39A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 37 | 2 | 2 | 0 |
DFFB_ENST00000378209 | DFFB | O76075 | DNA fragmentation factor subunit beta | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 37 | 27 | 1 | 1 | 0 |
DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 120 | 52 | 8 | 8 | 3 |
DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 37 | 153 | 16 | 16 | 0 |
DUSP16 | DUSP16 | Q9BY84 | Dual specificity protein phosphatase 16 | chr12 | Compendium | Yes | 1 | hippie, biogrid | 70 | 273 | 34 | 34 | 0 |
DYNLL1_ENST00000242577 | DYNLL1 | P63167 | Dynein light chain 1, cytoplasmic | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 9 | 0 | 0 | 0 | 0 |
DYNLL2 | DYNLL2 | Q96FJ2 | Dynein light chain 2, cytoplasmic | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 0 | 0 | 0 | 0 |
DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | Not Cancer Driver | No | 4 | hippie, biogrid | 135 | 447 | 73 | 73 | 0 |
ETFB_ENST00000309244 | ETFB | P38117 | Electron transfer flavoprotein subunit beta | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 37 | 38 | 4 | 4 | 2 |
FAU | FAU | P62861 | FAU ubiquitin-like and ribosomal protein S30 | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 61 | 12 | 12 | 0 |
FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 22 | 22 | 0 |
FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | Not Cancer Driver | No | 1 | hippie | 75 | 243 | 38 | 38 | 1 |
FGD5 | FGD5 | Q6ZNL6 | FYVE, RhoGEF and PH domain-containing protein 5 | chr3 | Compendium | Yes | 1 | hippie, biogrid | 275 | 915 | 180 | 180 | 0 |
FGF14_ENST00000376143 | FGF14 | Q92915 | Fibroblast growth factor 14 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 93 | 30 | 30 | 1 |
FGFR1OP | CEP43 | O95684 | Centrosomal protein 43 | chr6 | Not Cancer Driver | No | 1 | intact | 43 | 272 | 33 | 33 | 0 |
FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 53 | 8 | 8 | 8 |
FKBP5 | FKBP5 | Q13451 | Peptidyl-prolyl cis-trans isomerase FKBP5 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 70 | 150 | 20 | 20 | 0 |
FLNA | FLNA | P21333 | Filamin-A | chrX | Census | Yes | 1 | intact, hippie | 416 | 1456 | 214 | 214 | 28 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | Not Cancer Driver | No | 1 | hippie | 65 | 288 | 42 | 42 | 62 |
GPKOW | GPKOW | Q92917 | G-patch domain and KOW motifs-containing protein | chrX | Not Cancer Driver | No | 1 | hippie | 80 | 396 | 71 | 71 | 0 |
GPR161_ENST00000367835 | GPR161 | Q8N6U8 | G-protein coupled receptor 161 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 84 | 108 | 16 | 16 | 0 |
GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 180 | 8 | 8 | 0 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 56 | 146 | 13 | 13 | 0 |
HIST1H2BH | H2BC9 | Q93079 | Histone H2B type 1-H | chr6 | Not Cancer Driver | No | 1 | intact | 42 | 79 | 20 | 20 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HP | HP | P00738 | Haptoglobin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 57 | 2 | 2 | 1 |
HRNR | HRNR | Q86YZ3 | Hornerin | chr1 | Not Cancer Driver | No | 1 | hippie | 612 | 2767 | 601 | 601 | 0 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 2 | intact, hippie | 106 | 257 | 37 | 37 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 2 | intact, hippie | 100 | 254 | 43 | 43 | 0 |
HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 268 | 35 | 35 | 0 |
HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 200 | 13 | 13 | 0 |
HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 93 | 286 | 38 | 38 | 0 |
HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 283 | 26 | 26 | 2 |
IRS4 | IRS4 | O14654 | Insulin receptor substrate 4 | chrX | Census, Compendium | Yes | 1 | hippie | 297 | 798 | 203 | 203 | 0 |
KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
KLHL28_ENST00000396128 | KLHL28 | Q9NXS3 | Kelch-like protein 28 | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 81 | 20 | 2 | 2 | 0 |
MAP2 | MAP2 | P11137 | Microtubule-associated protein 2 | chr2 | Compendium | Yes | 1 | hippie, biogrid | 367 | 1726 | 340 | 340 | 0 |
MAP7D1 | MAP7D1 | Q3KQU3 | MAP7 domain-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 99 | 817 | 90 | 90 | 0 |
MAPRE1 | MAPRE1 | Q15691 | Microtubule-associated protein RP/EB family member 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 26 | 109 | 11 | 11 | 0 |
MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | Not Cancer Driver | No | 1 | hippie | 70 | 411 | 58 | 58 | 0 |
MLF1_ENST00000355893 | MLF1 | P58340 | Myeloid leukemia factor 1 | chr3 | Census | Yes | 3 | hippie, biogrid | 40 | 243 | 37 | 37 | 0 |
MRPS15 | MRPS15 | P82914 | 28S ribosomal protein S15, mitochondrial | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 35 | 72 | 7 | 7 | 0 |
MYH1 | MYH1 | P12882 | Myosin-1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 546 | 1153 | 335 | 335 | 0 |
MYH2_ENST00000397183 | MYH2 | Q9UKX2 | Myosin-2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 572 | 1073 | 338 | 338 | 1 |
MYH4 | MYH4 | Q9Y623 | Myosin-4 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 464 | 1138 | 288 | 288 | 0 |
MYH6 | MYH6 | P13533 | Myosin-6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 392 | 1112 | 238 | 238 | 7 |
MYL1 | MYL1 | P05976 | Myosin light chain 1/3, skeletal muscle isoform | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 104 | 31 | 31 | 1 |
NAA11 | NAA11 | Q9BSU3 | N-alpha-acetyltransferase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 123 | 31 | 31 | 0 |
NALCN | NALCN | Q8IZF0 | Sodium leak channel NALCN | chr13 | Not Cancer Driver | No | 1 | hippie | 499 | 260 | 74 | 74 | 11 |
NAPG | NAPG | Q99747 | Gamma-soluble NSF attachment protein | chr18 | Not Cancer Driver | No | 3 | hippie, biogrid | 35 | 56 | 3 | 3 | 0 |
NEFH | NEFH | P12036 | Neurofilament heavy polypeptide | chr22 | Compendium | Yes | 1 | hippie | 114 | 871 | 106 | 106 | 0 |
NGFR | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | Not Cancer Driver | No | 1 | hippie | 57 | 172 | 25 | 25 | 0 |
NIN | NIN | Q8N4C6 | Ninein | chr14 | Census, Compendium | Yes | 1 | hippie | 239 | 1392 | 164 | 164 | 2 |
NPAS1_ENST00000449844 | NPAS1 | Q99742 | Neuronal PAS domain-containing protein 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 53 | 309 | 23 | 23 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUAK1 | NUAK1 | O60285 | NUAK family SNF1-like kinase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 357 | 77 | 77 | 0 |
OXSR1 | OXSR1 | O95747 | Serine/threonine-protein kinase OSR1 | chr3 | Not Cancer Driver | No | 1 | hippie | 69 | 208 | 29 | 29 | 0 |
PALM2-AKAP2 | PALM2-AKAP2 | Q9Y2D5-4 | Isoform 3 of A-kinase anchor protein 2 | chr9 | Not Cancer Driver | No | 1 | biogrid | 179 | 1072 | 178 | 178 | 0 |
PDE4DIP_ENST00000369354 | PDE4DIP | Q5VU43 | Myomegalin | chr1 | Census, Compendium | Yes | 4 | intact, hippie, biogrid | 555 | 1633 | 395 | 395 | 0 |
PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | Census | Yes | 1 | hippie, biogrid | 160 | 948 | 116 | 116 | 0 |
PFDN1 | PFDN1 | O60925 | Prefoldin subunit 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 42 | 4 | 4 | 0 |
PGAM5 | PGAM5 | Q96HS1 | Serine/threonine-protein phosphatase PGAM5, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 102 | 12 | 12 | 0 |
PICK1 | PICK1 | Q9NRD5 | PRKCA-binding protein | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 49 | 3 | 3 | 0 |
PITX2_ENST00000354925 | PITX2 | Q99697 | Pituitary homeobox 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 185 | 43 | 43 | 13 |
PKIA | PKIA | P61925 | cAMP-dependent protein kinase inhibitor alpha | chr8 | Not Cancer Driver | No | 1 | hippie | 18 | 76 | 18 | 18 | 0 |
PKIB_ENST00000368448 | PKIB | Q9C010 | cAMP-dependent protein kinase inhibitor beta | chr6 | Not Cancer Driver | No | 1 | hippie | 13 | 78 | 13 | 13 | 0 |
PKIG_ENST00000372891 | PKIG | Q9Y2B9 | cAMP-dependent protein kinase inhibitor gamma | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 15 | 76 | 15 | 15 | 0 |
PKP2 | PKP2 | Q99959 | Plakophilin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 176 | 434 | 98 | 98 | 8 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
POLRMT | POLRMT | O00411 | DNA-directed RNA polymerase, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 188 | 253 | 31 | 31 | 0 |
PRKACA | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | Census | Yes | 7 | intact, hippie, biogrid | 53 | 24 | 0 | 0 | 2 |
PRKACB_ENST00000370689 | PRKACB | P22694 | cAMP-dependent protein kinase catalytic subunit beta | chr1 | Not Cancer Driver | No | 1 | hippie | 50 | 26 | 6 | 6 | 4 |
PRKACG | PRKACG | P22612 | cAMP-dependent protein kinase catalytic subunit gamma | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 74 | 23 | 7 | 7 | 1 |
PRKAR1A_ENST00000536854 | PRKAR1A | P10644 | cAMP-dependent protein kinase type I-alpha regulatory subunit | chr17 | Census, Compendium | Yes | 5 | hippie, biogrid | 39 | 66 | 11 | 11 | 17 |
PRKAR1B_ENST00000403562 | PRKAR1B | P31321 | cAMP-dependent protein kinase type I-beta regulatory subunit | chr7 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 53 | 71 | 13 | 13 | 0 |
PRKAR2A | PRKAR2A | P13861 | cAMP-dependent protein kinase type II-alpha regulatory subunit | chr3 | Not Cancer Driver | No | 6 | hippie, biogrid | 37 | 149 | 13 | 13 | 0 |
PRKAR2B | PRKAR2B | P31323 | cAMP-dependent protein kinase type II-beta regulatory subunit | chr7 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 60 | 125 | 4 | 4 | 0 |
PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | Not Cancer Driver | No | 1 | hippie | 110 | 120 | 16 | 16 | 0 |
PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 70 | 116 | 11 | 11 | 0 |
PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 538 | 421 | 61 | 61 | 2 |
PTN | PTN | P21246 | Pleiotrophin | chr7 | Not Cancer Driver | No | 1 | hippie | 43 | 51 | 11 | 11 | 0 |
RABGGTB | RABGGTB | P53611 | Geranylgeranyl transferase type-2 subunit beta | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 50 | 4 | 1 | 1 | 0 |
RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
RAD51B_ENST00000487270 | RAD51B | O15315 | DNA repair protein RAD51 homolog 2 | chr14 | Census | Yes | 1 | hippie, biogrid | 45 | 13 | 0 | 0 | 0 |
RAPGEF5_ENST00000401957 | RAPGEF5 | Q92565 | Rap guanine nucleotide exchange factor 5 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 73 | 56 | 10 | 10 | 0 |
RCAN1_ENST00000313806 | RCAN1 | P53805 | Calcipressin-1 | chr21 | Not Cancer Driver | No | 1 | hippie | 26 | 104 | 7 | 7 | 0 |
RCN2_ENST00000394885 | RCN2 | Q14257 | Reticulocalbin-2 | chr15 | Not Cancer Driver | No | 1 | hippie | 35 | 125 | 11 | 11 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RNF216_ENST00000425013 | RNF216 | Q9NWF9 | E3 ubiquitin-protein ligase RNF216 | chr7 | Not Cancer Driver | No | 1 | hippie | 108 | 415 | 57 | 57 | 2 |
RPE | RPE | Q96AT9 | Ribulose-phosphate 3-epimerase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 28 | 6 | 6 | 0 |
RPL13_ENST00000393099 | RPL13 | P26373 | 60S ribosomal protein L13 | chr16 | Not Cancer Driver | No | 1 | hippie | 14 | 160 | 11 | 11 | 1 |
RPL17_ENST00000579248 | RPL17 | P18621 | 60S ribosomal protein L17 | chr18 | Not Cancer Driver | No | 1 | hippie | 26 | 97 | 14 | 14 | 0 |
RPL19 | RPL19 | P84098 | 60S ribosomal protein L19 | chr17 | Not Cancer Driver | No | 1 | hippie | 30 | 121 | 21 | 21 | 0 |
RPL21_ENST00000326092 | RPL21 | P46778 | 60S ribosomal protein L21 | chr13 | Not Cancer Driver | No | 1 | hippie | 15 | 103 | 11 | 11 | 1 |
RPL22 | RPL22 | P35268 | 60S ribosomal protein L22 | chr1 | Census, Compendium | Yes | 1 | hippie | 26 | 15 | 1 | 1 | 0 |
RPL23A | RPL23A | P62750 | 60S ribosomal protein L23a | chr17 | Not Cancer Driver | No | 1 | hippie | 21 | 70 | 13 | 13 | 0 |
RPL23_ENST00000394332 | RPL23 | P62829 | 60S ribosomal protein L23 | chr17 | Not Cancer Driver | No | 1 | hippie | 14 | 29 | 4 | 4 | 0 |
RPL24 | RPL24 | P83731 | 60S ribosomal protein L24 | chr3 | Not Cancer Driver | No | 1 | hippie | 19 | 105 | 14 | 14 | 0 |
RPL27A | RPL27A | P46776 | 60S ribosomal protein L27a | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 7 | 56 | 2 | 2 | 0 |
RPL28_ENST00000559463 | RPL28 | P46779 | 60S ribosomal protein L28 | chr19 | Not Cancer Driver | No | 1 | hippie | 29 | 115 | 24 | 24 | 0 |
RPL35 | RPL35 | P42766 | 60S ribosomal protein L35 | chr9 | Not Cancer Driver | No | 1 | hippie | 12 | 65 | 9 | 9 | 0 |
RPL36A_ENST00000553110 | RPL36A | P83881 | 60S ribosomal protein L36a | chrX | Not Cancer Driver | No | 1 | hippie | 17 | 64 | 10 | 10 | 0 |
RPL38_ENST00000439590 | RPL38 | P63173 | 60S ribosomal protein L38 | chr17 | Not Cancer Driver | No | 1 | hippie | 2 | 9 | 0 | 0 | 0 |
RPL4 | RPL4 | P36578 | 60S ribosomal protein L4 | chr15 | Not Cancer Driver | No | 1 | hippie | 49 | 222 | 31 | 31 | 0 |
RPS11 | RPS11 | P62280 | 40S ribosomal protein S11 | chr19 | Not Cancer Driver | No | 1 | hippie | 18 | 6 | 0 | 0 | 0 |
RPS13 | RPS13 | P62277 | 40S ribosomal protein S13 | chr11 | Not Cancer Driver | No | 1 | hippie | 19 | 18 | 5 | 5 | 0 |
RPS14_ENST00000521466 | RPS14 | P62263 | 40S ribosomal protein S14 | chr5 | Not Cancer Driver | No | 1 | hippie | 14 | 96 | 13 | 13 | 0 |
RPS15_ENST00000592588 | RPS15 | P62841 | 40S ribosomal protein S15 | chr19 | Not Cancer Driver | No | 1 | hippie | 13 | 59 | 7 | 7 | 0 |
RPS16 | RPS16 | P62249 | 40S ribosomal protein S16 | chr19 | Not Cancer Driver | No | 1 | hippie | 16 | 14 | 1 | 1 | 0 |
RPS18 | RPS18 | P62269 | 40S ribosomal protein S18 | chr6 | Not Cancer Driver | No | 1 | hippie | 28 | 27 | 8 | 8 | 0 |
RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | Not Cancer Driver | No | 1 | hippie | 15 | 61 | 3 | 3 | 23 |
RPS2 | RPS2 | P15880 | 40S ribosomal protein S2 | chr16 | Not Cancer Driver | No | 1 | hippie | 34 | 85 | 14 | 14 | 0 |
RPS23 | RPS23 | P62266 | 40S ribosomal protein S23 | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 35 | 1 | 1 | 2 |
RPS24_ENST00000613865 | RPS24 | P62847 | 40S ribosomal protein S24 | chr10 | Not Cancer Driver | No | 1 | hippie | 13 | 88 | 10 | 10 | 0 |
RPS25 | RPS25 | P62851 | 40S ribosomal protein S25 | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 60 | 8 | 8 | 0 |
RPS26_ENST00000646449 | RPS26 | P62854 | 40S ribosomal protein S26 | chr12 | Not Cancer Driver | No | 1 | hippie | 9 | 52 | 5 | 5 | 2 |
RPS27 | RPS27 | P42677 | 40S ribosomal protein S27 | chr1 | Not Cancer Driver | No | 1 | hippie | 10 | 29 | 7 | 7 | 0 |
RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | Not Cancer Driver | No | 1 | hippie | 4 | 22 | 2 | 2 | 0 |
RPS29_ENST00000245458 | RPS29 | P62273 | 40S ribosomal protein S29 | chr14 | Not Cancer Driver | No | 1 | hippie | 7 | 0 | 0 | 0 | 2 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 48 | 4 | 4 | 0 |
RPS4X | RPS4X | P62701 | 40S ribosomal protein S4, X isoform | chrX | Not Cancer Driver | No | 1 | hippie | 32 | 35 | 6 | 6 | 0 |
RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 150 | 25 | 25 | 0 |
RYR2 | RYR2 | Q92736 | Ryanodine receptor 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 1703 | 782 | 281 | 281 | 51 |
SLC25A3 | SLC25A3 | Q00325 | Phosphate carrier protein, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 49 | 32 | 4 | 4 | 1 |
SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | Census, Compendium | Yes | 1 | intact, hippie | 22 | 66 | 3 | 3 | 2 |
SPP1 | SPP1 | P10451 | Osteopontin | chr4 | Not Cancer Driver | No | 1 | hippie | 56 | 296 | 54 | 54 | 0 |
SULF2_ENST00000484875 | SULF2 | Q8IWU5 | Extracellular sulfatase Sulf-2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 145 | 142 | 18 | 18 | 0 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
TALDO1 | TALDO1 | P37837 | Transaldolase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 31 | 4 | 4 | 0 |
TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie | 54 | 55 | 10 | 10 | 0 |
TF | TF | P02787 | Serotransferrin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 135 | 21 | 5 | 5 | 2 |
TIMP3 | TIMP3 | P35625 | Metalloproteinase inhibitor 3 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 3 | 1 | 1 | 5 |
TNP1 | TNP1 | P09430 | Spermatid nuclear transition protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 21 | 55 | 21 | 21 | 0 |
TNP2 | TNP2 | Q05952 | Nuclear transition protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 23 | 138 | 23 | 23 | 0 |
TP53RK | TP53RK | Q96S44 | EKC/KEOPS complex subunit TP53RK | chr20 | Not Cancer Driver | No | 1 | hippie | 20 | 51 | 2 | 2 | 3 |
TP73 | TP73 | O15350 | Tumor protein p73 | chr1 | Not Cancer Driver | No | 1 | hippie | 82 | 443 | 55 | 55 | 0 |
TPRKB_ENST00000272424 | TPRKB | Q9Y3C4 | EKC/KEOPS complex subunit TPRKB | chr2 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 2 |
TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | Compendium | Yes | 1 | hippie | 61 | 101 | 9 | 9 | 1 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 67 | 62 | 7 | 7 | 0 |
TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 110 | 11 | 11 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TUBA1C_ENST00000301072 | TUBA1C | Q9BQE3 | Tubulin alpha-1C chain | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 50 | 5 | 5 | 0 |
TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 63 | 11 | 11 | 5 |
TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | Not Cancer Driver | No | 1 | hippie | 52 | 65 | 11 | 11 | 2 |
VAPA_ENST00000400000 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 24 | 184 | 14 | 14 | 0 |
VAPB | VAPB | O95292 | Vesicle-associated membrane protein-associated protein B/C | chr20 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 16 | 138 | 8 | 8 | 3 |
VIM_ENST00000224237 | VIM | P08670 | Vimentin | chr10 | Not Cancer Driver | No | 1 | hippie | 84 | 316 | 57 | 57 | 1 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 1 | hippie | 26 | 77 | 9 | 9 | 2 |
ZNF641_ENST00000301042 | ZNF641 | Q96N77 | Zinc finger protein 641 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 280 | 28 | 28 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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