Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCB7_ENST00000373394 | ABCB7 | O75027 | Iron-sulfur clusters transporter ABCB7, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie | 117 | 79 | 14 | 14 | 4 |
| ABHD17B_ENST00000333421 | ABHD17B | Q5VST6 | Alpha/beta hydrolase domain-containing protein 17B | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 0 | 0 | 0 | 0 |
| ABHD17C | ABHD17C | Q6PCB6 | Alpha/beta hydrolase domain-containing protein 17C | chr15 | Not Cancer Driver | No | 1 | hippie | 21 | 53 | 0 | 0 | 0 |
| ABHD3 | ABHD3 | Q8WU67 | Phospholipase ABHD3 | chr18 | Not Cancer Driver | No | 1 | hippie | 43 | 0 | 0 | 0 | 0 |
| ACAD10_ENST00000313698 | ACAD10 | Q6JQN1 | Acyl-CoA dehydrogenase family member 10 | chr12 | Not Cancer Driver | No | 1 | hippie | 143 | 91 | 19 | 19 | 0 |
| ACADSB | ACADSB | P45954 | Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 59 | 16 | 3 | 3 | 1 |
| ACSL1_ENST00000281455 | ACSL1 | P33121 | Long-chain-fatty-acid--CoA ligase 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 85 | 27 | 1 | 1 | 0 |
| ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 39 | 4 | 4 | 17 |
| ADPGK | ADPGK | Q9BRR6 | ADP-dependent glucokinase | chr15 | Not Cancer Driver | No | 1 | hippie | 38 | 24 | 0 | 0 | 0 |
| AFG3L2 | AFG3L2 | Q9Y4W6 | AFG3-like protein 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 72 | 162 | 10 | 10 | 22 |
| AGPAT2_ENST00000538402 | AGPAT2 | O15120 | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta | chr9 | Not Cancer Driver | No | 1 | hippie | 25 | 23 | 2 | 2 | 3 |
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | Not Cancer Driver | No | 1 | hippie | 73 | 229 | 30 | 30 | 0 |
| APOB | APOB | P04114 | Apolipoprotein B-100 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 1022 | 315 | 72 | 72 | 3 |
| AREL1 | AREL1 | O15033 | Apoptosis-resistant E3 ubiquitin protein ligase 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 104 | 92 | 10 | 10 | 0 |
| ARFGEF1 | ARFGEF1 | Q9Y6D6 | Brefeldin A-inhibited guanine nucleotide-exchange protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 243 | 456 | 54 | 54 | 0 |
| ARFGEF2 | ARFGEF2 | Q9Y6D5 | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 254 | 358 | 63 | 63 | 0 |
| ARMC6 | ARMC6 | Q6NXE6 | Armadillo repeat-containing protein 6 | chr19 | Not Cancer Driver | No | 1 | hippie | 65 | 77 | 5 | 5 | 0 |
| ATL2 | ATL2 | Q8NHH9 | Atlastin-2 | chr2 | Not Cancer Driver | No | 1 | hippie | 64 | 75 | 5 | 5 | 0 |
| ATL3 | ATL3 | Q6DD88 | Atlastin-3 | chr11 | Not Cancer Driver | No | 1 | hippie | 43 | 57 | 5 | 5 | 1 |
| ATP11C | ATP11C | Q8NB49 | Phospholipid-transporting ATPase IG | chrX | Not Cancer Driver | No | 1 | intact, hippie | 198 | 32 | 5 | 5 | 1 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie | 200 | 115 | 29 | 29 | 31 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | Not Cancer Driver | No | 1 | hippie | 56 | 0 | 0 | 0 | 2 |
| ATP6V1H_ENST00000396774 | ATP6V1H | Q9UI12 | V-type proton ATPase subunit H | chr8 | Not Cancer Driver | No | 1 | hippie | 76 | 35 | 2 | 2 | 0 |
| ATXN10 | ATXN10 | Q9UBB4 | Ataxin-10 | chr22 | Not Cancer Driver | No | 1 | hippie | 46 | 37 | 2 | 2 | 0 |
| AUP1 | AUP1 | Q9Y679 | Lipid droplet-regulating VLDL assembly factor AUP1 | chr2 | Not Cancer Driver | No | 1 | hippie | 41 | 122 | 13 | 13 | 0 |
| BDH1 | BDH1 | Q02338 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 44 | 15 | 1 | 1 | 0 |
| BRAT1 | BRAT1 | Q6PJG6 | BRCA1-associated ATM activator 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 101 | 13 | 13 | 0 |
| BTAF1 | BTAF1 | O14981 | TATA-binding protein-associated factor 172 | chr10 | Not Cancer Driver | No | 1 | hippie | 215 | 360 | 52 | 52 | 0 |
| C19orf70_ENST00000309324 | MICOS13 | Q5XKP0 | MICOS complex subunit MIC13 | chr19 | Not Cancer Driver | No | 1 | hippie | 12 | 3 | 0 | 0 | 0 |
| C2CD2 | C2CD2 | Q9Y426 | C2 domain-containing protein 2 | chr21 | Not Cancer Driver | No | 1 | hippie | 83 | 385 | 56 | 56 | 0 |
| CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 161 | 88 | 7 | 7 | 0 |
| CCDC47_ENST00000403162 | CCDC47 | Q96A33 | PAT complex subunit CCDC47 | chr17 | Not Cancer Driver | No | 1 | hippie | 49 | 265 | 23 | 23 | 0 |
| CD63_ENST00000552692 | CD63 | P08962 | CD63 antigen | chr12 | Not Cancer Driver | No | 1 | hippie | 27 | 0 | 0 | 0 | 0 |
| CDKAL1 | CDKAL1 | Q5VV42 | Threonylcarbamoyladenosine tRNA methylthiotransferase | chr6 | Not Cancer Driver | No | 1 | hippie | 80 | 120 | 14 | 14 | 0 |
| CDS2 | CDS2 | O95674 | Phosphatidate cytidylyltransferase 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 48 | 49 | 4 | 4 | 0 |
| CHCHD6 | CHCHD6 | Q9BRQ6 | MICOS complex subunit MIC25 | chr3 | Not Cancer Driver | No | 1 | hippie | 27 | 194 | 24 | 24 | 0 |
| CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 27 | 70 | 12 | 12 | 0 |
| CHRM4 | CHRM4 | P08173 | Muscarinic acetylcholine receptor M4 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 143 | 27 | 27 | 0 |
| CIAO1 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 20 | 2 | 2 | 0 |
| CLN6 | CLN6 | Q9NWW5 | Ceroid-lipofuscinosis neuronal protein 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 28 | 13 | 0 | 0 | 24 |
| COG1 | COG1 | Q8WTW3 | Conserved oligomeric Golgi complex subunit 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 88 | 204 | 18 | 18 | 0 |
| COG4 | COG4 | Q9H9E3 | Conserved oligomeric Golgi complex subunit 4 | chr16 | Not Cancer Driver | No | 1 | hippie | 92 | 55 | 10 | 10 | 2 |
| COQ5 | COQ5 | Q5HYK3 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 15 | 2 | 2 | 0 |
| COQ8A | COQ8A | Q8NI60 | Atypical kinase COQ8A, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 95 | 166 | 29 | 29 | 12 |
| COQ8B | COQ8B | Q96D53 | Atypical kinase COQ8B, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 53 | 117 | 15 | 15 | 8 |
| CPT1A_ENST00000539743 | CPT1A | P50416 | Carnitine O-palmitoyltransferase 1, liver isoform | chr11 | Not Cancer Driver | No | 1 | hippie | 144 | 62 | 10 | 10 | 15 |
| CSE1L | CSE1L | P55060 | Exportin-2 | chr20 | Not Cancer Driver | No | 1 | hippie | 109 | 32 | 5 | 5 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | Not Cancer Driver | No | 1 | hippie | 26 | 66 | 2 | 2 | 12 |
| CYFIP2 | CYFIP2 | Q96F07 | Cytoplasmic FMR1-interacting protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 211 | 86 | 11 | 11 | 3 |
| CYP2S1 | CYP2S1 | Q96SQ9 | Cytochrome P450 2S1 | chr19 | Not Cancer Driver | No | 1 | hippie | 75 | 46 | 10 | 10 | 0 |
| CYSTM1 | CYSTM1 | Q9H1C7 | Cysteine-rich and transmembrane domain-containing protein 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 74 | 13 | 13 | 0 |
| DDX19B | DDX19B | Q9UMR2 | ATP-dependent RNA helicase DDX19B | chr16 | Not Cancer Driver | No | 1 | hippie | 44 | 113 | 9 | 9 | 0 |
| DDX20 | DDX20 | Q9UHI6 | Probable ATP-dependent RNA helicase DDX20 | chr1 | Not Cancer Driver | No | 1 | hippie | 89 | 299 | 33 | 33 | 0 |
| DECR2 | DECR2 | Q9NUI1 | Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] | chr16 | Not Cancer Driver | No | 1 | hippie | 44 | 36 | 2 | 2 | 0 |
| DERL2 | DERL2 | Q9GZP9 | Derlin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 15 | 1 | 1 | 0 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | Not Cancer Driver | No | 1 | hippie | 55 | 0 | 0 | 0 | 6 |
| DHCR7 | DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | chr11 | Not Cancer Driver | No | 1 | hippie | 85 | 7 | 1 | 1 | 53 |
| DHRS13 | DHRS13 | Q6UX07 | Dehydrogenase/reductase SDR family member 13 | chr17 | Not Cancer Driver | No | 1 | hippie | 26 | 101 | 8 | 8 | 0 |
| DHRS7B | DHRS7B | Q6IAN0 | Dehydrogenase/reductase SDR family member 7B | chr17 | Not Cancer Driver | No | 1 | hippie | 37 | 17 | 0 | 0 | 0 |
| DMAC2L | DMAC2L | Q99766 | ATP synthase subunit s, mitochondrial | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 0 | 0 | 0 | 0 |
| DNAAF5 | DNAAF5 | Q86Y56 | Dynein axonemal assembly factor 5 | chr7 | Not Cancer Driver | No | 1 | hippie | 89 | 81 | 0 | 0 | 1 |
| DNM1 | DNM1 | Q05193 | Dynamin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 98 | 280 | 23 | 23 | 4 |
| DOP1B | DOP1B | Q9Y3R5 | Protein dopey-2 | chr21 | Not Cancer Driver | No | 1 | hippie | 295 | 450 | 71 | 71 | 0 |
| DTYMK | DTYMK | P23919 | Thymidylate kinase | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 0 | 0 | 0 | 0 |
| EARS2_ENST00000449606 | EARS2 | Q5JPH6 | Probable glutamate--tRNA ligase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 56 | 99 | 14 | 14 | 14 |
| ECHDC1 | ECHDC1 | Q9NTX5 | Ethylmalonyl-CoA decarboxylase | chr6 | Not Cancer Driver | No | 1 | hippie | 37 | 10 | 0 | 0 | 0 |
| ECPAS_ENST00000338205 | ECPAS | Q5VYK3 | Proteasome adapter and scaffold protein ECM29 | chr9 | Not Cancer Driver | No | 1 | hippie | 176 | 240 | 22 | 22 | 0 |
| EI24 | EI24 | O14681 | Etoposide-induced protein 2.4 homolog | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 12 | 1 | 1 | 0 |
| EPHX4 | EPHX4 | Q8IUS5 | Epoxide hydrolase 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 60 | 1 | 0 | 0 | 0 |
| ERAP1_ENST00000443439 | ERAP1 | Q9NZ08 | Endoplasmic reticulum aminopeptidase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 78 | 70 | 2 | 2 | 0 |
| ERCC2 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | Census, Compendium | Yes | 1 | hippie | 150 | 5 | 0 | 0 | 35 |
| ESRP2_ENST00000565858 | ESRP2 | Q9H6T0 | Epithelial splicing regulatory protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 145 | 12 | 12 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 55 | 7 | 2 | 2 | 0 |
| FADS3 | FADS3 | Q9Y5Q0 | Fatty acid desaturase 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 54 | 47 | 2 | 2 | 0 |
| FANCA | FANCA | O15360 | Fanconi anemia group A protein | chr16 | Census, Compendium | Yes | 1 | hippie | 160 | 154 | 15 | 15 | 27 |
| FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
| FASTKD1 | FASTKD1 | Q53R41 | FAST kinase domain-containing protein 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 125 | 0 | 0 | 0 | 0 |
| FASTKD5 | FASTKD5 | Q7L8L6 | FAST kinase domain-containing protein 5, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie | 86 | 94 | 8 | 8 | 0 |
| FDFT1_ENST00000615631 | FDFT1 | P37268 | Squalene synthase | chr8 | Not Cancer Driver | No | 1 | hippie | 39 | 19 | 0 | 0 | 0 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 25 | 6 | 0 | 0 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie | 71 | 160 | 25 | 25 | 0 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 216 | 669 | 76 | 76 | 0 |
| GCN1 | GCN1 | Q92616 | eIF-2-alpha kinase activator GCN1 | chr12 | Not Cancer Driver | No | 1 | hippie | 327 | 117 | 16 | 16 | 0 |
| GEMIN4 | GEMIN4 | P57678 | Gem-associated protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 24 | 1 | 1 | 0 |
| GK | GK | P32189 | Glycerol kinase | chrX | Not Cancer Driver | No | 1 | intact, hippie | 85 | 15 | 3 | 3 | 3 |
| GOLGA7_ENST00000518270 | GOLGA7 | Q7Z5G4 | Golgin subfamily A member 7 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 6 | 0 | 0 | 0 |
| GPAT3_ENST00000395226 | GPAT3 | Q53EU6 | Glycerol-3-phosphate acyltransferase 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 56 | 3 | 0 | 0 | 0 |
| GPAT4 | GPAT4 | Q86UL3 | Glycerol-3-phosphate acyltransferase 4 | chr8 | Not Cancer Driver | No | 1 | hippie | 64 | 3 | 0 | 0 | 0 |
| HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 44 | 219 | 32 | 32 | 2 |
| HEATR1 | HEATR1 | Q9H583 | HEAT repeat-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 291 | 43 | 5 | 5 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 94 | 524 | 34 | 34 | 0 |
| HSD17B12 | HSD17B12 | Q53GQ0 | Very-long-chain 3-oxoacyl-CoA reductase | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 9 | 0 | 0 | 0 |
| ICMT | ICMT | O60725 | Protein-S-isoprenylcysteine O-methyltransferase | chr1 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
| IFITM3 | IFITM3 | Q01628 | Interferon-induced transmembrane protein 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 69 | 18 | 5 | 5 | 0 |
| IMMT | IMMT | Q16891 | MICOS complex subunit MIC60 | chr2 | Not Cancer Driver | No | 1 | hippie | 97 | 400 | 50 | 50 | 0 |
| INTS1 | INTS1 | Q8N201 | Integrator complex subunit 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 234 | 368 | 43 | 43 | 1 |
| INTS3_ENST00000435409 | INTS3 | Q68E01 | Integrator complex subunit 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 125 | 213 | 25 | 25 | 0 |
| IPO11_ENST00000325324 | IPO11 | Q9UI26 | Importin-11 | chr5 | Not Cancer Driver | No | 1 | hippie | 82 | 66 | 4 | 4 | 0 |
| IPO13 | IPO13 | O94829 | Importin-13 | chr1 | Not Cancer Driver | No | 1 | hippie | 98 | 42 | 7 | 7 | 0 |
| IPO8 | IPO8 | O15397 | Importin-8 | chr12 | Not Cancer Driver | No | 1 | hippie | 130 | 111 | 13 | 13 | 0 |
| IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | Compendium | Yes | 1 | hippie | 71 | 337 | 39 | 39 | 0 |
| JAK1 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | Census, Compendium | Yes | 1 | hippie | 147 | 120 | 7 | 7 | 2 |
| KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 32 | 0 | 0 | 0 | 0 |
| LGALS3 | LGALS3 | P17931 | Galectin-3 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 133 | 6 | 6 | 0 |
| LPCAT1 | LPCAT1 | Q8NF37 | Lysophosphatidylcholine acyltransferase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 66 | 11 | 11 | 0 |
| LRRC8E | LRRC8E | Q6NSJ5 | Volume-regulated anion channel subunit LRRC8E | chr19 | Not Cancer Driver | No | 1 | hippie | 77 | 35 | 0 | 0 | 0 |
| MAN1A1 | MAN1A1 | P33908 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA | chr6 | Not Cancer Driver | No | 1 | hippie | 118 | 134 | 23 | 23 | 0 |
| MAP2K3 | MAP2K3 | P46734 | Dual specificity mitogen-activated protein kinase kinase 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 104 | 75 | 27 | 27 | 0 |
| MFSD3 | MFSD3 | Q96ES6 | Major facilitator superfamily domain-containing protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 24 | 13 | 0 | 0 | 0 |
| MMS19 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | Not Cancer Driver | No | 1 | hippie | 73 | 11 | 0 | 0 | 0 |
| MON2 | MON2 | Q7Z3U7 | Protein MON2 homolog | chr12 | Not Cancer Driver | No | 1 | hippie | 201 | 151 | 16 | 16 | 0 |
| MPDU1 | MPDU1 | O75352 | Mannose-P-dolichol utilization defect 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie | 16 | 4 | 2 | 2 | 3 |
| MSI1 | MSI1 | O43347 | RNA-binding protein Musashi homolog 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 133 | 16 | 16 | 0 |
| MSMO1 | MSMO1 | Q15800 | Methylsterol monooxygenase 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 42 | 4 | 0 | 0 | 2 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | Census, Compendium | Yes | 1 | hippie | 379 | 296 | 37 | 37 | 18 |
| MTX1 | MTX1 | Q13505 | Metaxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 25 | 221 | 7 | 7 | 0 |
| MTX2 | MTX2 | O75431 | Metaxin-2 | chr2 | Not Cancer Driver | No | 1 | hippie | 33 | 0 | 0 | 0 | 0 |
| MZT2B_ENST00000281871 | MZT2B | Q6NZ67 | Mitotic-spindle organizing protein 2B | chr2 | Not Cancer Driver | No | 1 | hippie | 14 | 113 | 14 | 14 | 0 |
| NDFIP2_ENST00000218652 | NDFIP2 | Q9NV92 | NEDD4 family-interacting protein 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 27 | 198 | 13 | 13 | 0 |
| NFXL1 | NFXL1 | Q6ZNB6 | NF-X1-type zinc finger protein NFXL1 | chr4 | Not Cancer Driver | No | 1 | hippie | 102 | 183 | 15 | 15 | 0 |
| NOM1 | NOM1 | Q5C9Z4 | Nucleolar MIF4G domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 114 | 407 | 42 | 42 | 0 |
| NR2F1_ENST00000327111 | NR2F1 | P10589 | COUP transcription factor 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 110 | 6 | 6 | 4 |
| NTSR1 | NTSR1 | P30989 | Neurotensin receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 85 | 23 | 1 | 1 | 0 |
| PANK4 | PANK4 | Q9NVE7 | 4'-phosphopantetheine phosphatase | chr1 | Not Cancer Driver | No | 1 | hippie | 92 | 71 | 15 | 15 | 0 |
| PDS5A | PDS5A | Q29RF7 | Sister chromatid cohesion protein PDS5 homolog A | chr4 | Not Cancer Driver | No | 1 | hippie | 150 | 295 | 34 | 34 | 0 |
| PDXDC1 | PDXDC1 | Q6P996 | Pyridoxal-dependent decarboxylase domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 95 | 272 | 29 | 29 | 0 |
| PEX3 | PEX3 | P56589 | Peroxisomal biogenesis factor 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 31 | 24 | 0 | 0 | 2 |
| PI4KA | PI4KA | P42356 | Phosphatidylinositol 4-kinase alpha | chr22 | Not Cancer Driver | No | 1 | hippie | 267 | 142 | 11 | 11 | 1 |
| PISD_ENST00000439502 | PISD | Q9UG56 | Phosphatidylserine decarboxylase proenzyme, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie | 42 | 8 | 3 | 3 | 2 |
| POLD3 | POLD3 | Q15054 | DNA polymerase delta subunit 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 326 | 39 | 39 | 0 |
| PRAME_ENST00000402697 | PRAME | P78395 | Melanoma antigen preferentially expressed in tumors | chr22 | Not Cancer Driver | No | 1 | hippie | 95 | 10 | 1 | 1 | 0 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 61 | 134 | 21 | 21 | 96 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 1 | hippie | 23 | 67 | 6 | 6 | 0 |
| PTPMT1 | PTPMT1 | Q8WUK0 | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 0 | 0 | 0 | 0 |
| PYCR2 | PYCR2 | Q96C36 | Pyrroline-5-carboxylate reductase 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 41 | 3 | 3 | 2 |
| RAB18_ENST00000356940 | RAB18 | Q9NP72 | Ras-related protein Rab-18 | chr10 | Not Cancer Driver | No | 1 | hippie | 19 | 18 | 2 | 2 | 1 |
| RAB29 | RAB29 | O14966 | Ras-related protein Rab-7L1 | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 18 | 3 | 3 | 0 |
| RAB38 | RAB38 | P57729 | Ras-related protein Rab-38 | chr11 | Not Cancer Driver | No | 1 | hippie | 27 | 0 | 0 | 0 | 0 |
| RARS2 | RARS2 | Q5T160 | Probable arginine--tRNA ligase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 88 | 20 | 1 | 1 | 0 |
| RELCH | RELCH | Q9P260 | RAB11-binding protein RELCH | chr18 | Not Cancer Driver | No | 1 | hippie | 114 | 384 | 29 | 29 | 0 |
| RER1 | RER1 | O15258 | Protein RER1 | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 15 | 3 | 3 | 0 |
| RFT1 | RFT1 | Q96AA3 | Protein RFT1 homolog | chr3 | Not Cancer Driver | No | 1 | hippie | 38 | 4 | 0 | 0 | 3 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 1355 | 164 | 164 | 0 |
| RNF213 | RNF213 | Q63HN8 | E3 ubiquitin-protein ligase RNF213 | chr17 | Census, Compendium | Yes | 1 | hippie | 560 | 623 | 75 | 75 | 3 |
| RSAD1 | RSAD1 | Q9HA92 | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 68 | 88 | 13 | 13 | 0 |
| SACM1L | SACM1L | Q9NTJ5 | Phosphatidylinositol-3-phosphatase SAC1 | chr3 | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
| SAMM50 | SAMM50 | Q9Y512 | Sorting and assembly machinery component 50 homolog | chr22 | Not Cancer Driver | No | 1 | hippie | 51 | 34 | 1 | 1 | 0 |
| SEC61A2 | SEC61A2 | Q9H9S3 | Protein transport protein Sec61 subunit alpha isoform 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 55 | 0 | 0 | 0 | 0 |
| SFXN4 | SFXN4 | Q6P4A7 | Sideroflexin-4 | chr10 | Not Cancer Driver | No | 1 | hippie | 41 | 25 | 2 | 2 | 0 |
| SGPL1 | SGPL1 | O95470 | Sphingosine-1-phosphate lyase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 68 | 19 | 3 | 3 | 2 |
| SIGMAR1 | SIGMAR1 | Q99720 | Sigma non-opioid intracellular receptor 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 22 | 2 | 0 | 0 | 1 |
| SKIV2L | SKIV2L | Q15477 | Helicase SKI2W | chr6 | Not Cancer Driver | No | 1 | hippie | 140 | 390 | 54 | 54 | 1 |
| SLC25A19_ENST00000416858 | SLC25A19 | Q9HC21 | Mitochondrial thiamine pyrophosphate carrier | chr17 | Not Cancer Driver | No | 1 | hippie | 34 | 16 | 0 | 0 | 2 |
| SLC25A24 | SLC25A24 | Q6NUK1 | Calcium-binding mitochondrial carrier protein SCaMC-1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 21 | 2 | 2 | 2 |
| SLC25A29 | SLC25A29 | Q8N8R3 | Mitochondrial basic amino acids transporter | chr14 | Not Cancer Driver | No | 1 | hippie | 9 | 22 | 0 | 0 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 9 |
| SLC25A40 | SLC25A40 | Q8TBP6 | Probable mitochondrial glutathione transporter SLC25A40 | chr7 | Not Cancer Driver | No | 1 | hippie | 41 | 9 | 0 | 0 | 0 |
| SLC25A6 | SLC25A6 | P12236 | ADP/ATP translocase 3 | chrX | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
| SLC27A3_ENST00000271857 | SLC27A3 | X6R3N0 | Solute carrier family 27 (Fatty acid transporter), member 3, isoform CRA_d | chr1 | Not Cancer Driver | No | 1 | hippie | 80 | 171 | 16 | 16 | 0 |
| SLC35E1 | SLC35E1 | Q96K37 | Solute carrier family 35 member E1 | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 50 | 6 | 6 | 0 |
| SLC39A10_ENST00000359634 | SLC39A10 | Q9ULF5 | Zinc transporter ZIP10 | chr2 | Not Cancer Driver | No | 1 | hippie | 111 | 417 | 63 | 63 | 0 |
| SLC39A14_ENST00000381237 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | Not Cancer Driver | No | 1 | hippie | 34 | 42 | 3 | 3 | 4 |
| SLC39A6_ENST00000590986 | SLC39A6 | Q13433 | Zinc transporter ZIP6 | chr18 | Not Cancer Driver | No | 1 | hippie | 86 | 360 | 37 | 37 | 0 |
| SLC5A3 | SLC5A3 | P53794 | Sodium/myo-inositol cotransporter | chr21 | Not Cancer Driver | No | 1 | hippie | 81 | 73 | 6 | 6 | 0 |
| SLC7A1 | SLC7A1 | P30825 | High affinity cationic amino acid transporter 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 89 | 17 | 3 | 3 | 0 |
| SLC7A2_ENST00000494857 | SLC7A2 | P52569 | Cationic amino acid transporter 2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 113 | 36 | 6 | 6 | 0 |
| SLCO4A1 | SLCO4A1 | Q96BD0 | Solute carrier organic anion transporter family member 4A1 | chr20 | Not Cancer Driver | No | 1 | hippie | 106 | 66 | 5 | 5 | 0 |
| SMAP2 | SMAP2 | Q8WU79 | Stromal membrane-associated protein 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 214 | 30 | 30 | 0 |
| SMPD4 | SMPD4 | Q9NXE4 | Sphingomyelin phosphodiesterase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 114 | 80 | 12 | 12 | 1 |
| SPG7 | SPG7 | Q9UQ90 | Paraplegin | chr16 | Not Cancer Driver | No | 1 | hippie | 97 | 181 | 29 | 29 | 4 |
| SRPRA | SRPRA | P08240 | Signal recognition particle receptor subunit alpha | chr11 | Not Cancer Driver | No | 1 | hippie | 95 | 232 | 40 | 40 | 0 |
| STARD3 | STARD3 | Q14849 | StAR-related lipid transfer protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 34 | 6 | 6 | 0 |
| STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | Not Cancer Driver | No | 1 | hippie | 131 | 144 | 25 | 25 | 26 |
| STX17_ENST00000534052 | STX17 | P56962 | Syntaxin-17 | chr9 | Not Cancer Driver | No | 1 | hippie | 27 | 81 | 4 | 4 | 0 |
| SURF4 | SURF4 | O15260 | Surfeit locus protein 4 | chr9 | Not Cancer Driver | No | 1 | hippie | 29 | 0 | 0 | 0 | 0 |
| SYNGR2_ENST00000585591 | SYNGR2 | O43760 | Synaptogyrin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 30 | 24 | 9 | 9 | 0 |
| SYNJ2BP | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | Not Cancer Driver | No | 1 | hippie | 27 | 12 | 4 | 4 | 0 |
| TAP1 | TAP1 | Q03518-2 | Isoform 2 of Antigen peptide transporter 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 67 | 83 | 6 | 6 | 0 |
| TAP2 | TAP2 | Q03519 | Antigen peptide transporter 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 71 | 20 | 1 | 1 | 0 |
| TBCD | TBCD | Q9BTW9 | Tubulin-specific chaperone D | chr17 | Not Cancer Driver | No | 1 | hippie | 156 | 60 | 9 | 9 | 11 |
| TBL2 | TBL2 | Q9Y4P3 | Transducin beta-like protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 68 | 115 | 13 | 13 | 0 |
| TBRG4_ENST00000494076 | TBRG4 | Q969Z0 | FAST kinase domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie | 74 | 60 | 2 | 2 | 0 |
| TELO2 | TELO2 | Q9Y4R8 | Telomere length regulation protein TEL2 homolog | chr16 | Not Cancer Driver | No | 1 | hippie | 113 | 154 | 23 | 23 | 5 |
| TFB2M | TFB2M | Q9H5Q4 | Dimethyladenosine transferase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 60 | 36 | 6 | 6 | 0 |
| THADA_ENST00000405975 | THADA | Q6YHU6 | Thyroid adenoma-associated protein | chr2 | Not Cancer Driver | No | 1 | hippie | 204 | 63 | 6 | 6 | 0 |
| TM9SF1 | TM9SF1 | O15321 | Transmembrane 9 superfamily member 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 74 | 15 | 4 | 4 | 0 |
| TM9SF3 | TM9SF3 | Q9HD45 | Transmembrane 9 superfamily member 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 2 | 0 | 0 | 0 |
| TMEM126B | TMEM126B | Q8IUX1 | Complex I assembly factor TMEM126B, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 21 | 18 | 1 | 1 | 1 |
| TMEM209 | TMEM209 | Q96SK2 | Transmembrane protein 209 | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 193 | 27 | 27 | 0 |
| TMEM263_ENST00000551813 | TMEM263 | Q8WUH6 | Transmembrane protein 263 | chr12 | Not Cancer Driver | No | 1 | hippie | 6 | 63 | 3 | 3 | 0 |
| TMEM41B_ENST00000611268 | TMEM41B | Q5BJD5 | Transmembrane protein 41B | chr11 | Not Cancer Driver | No | 1 | hippie | 19 | 47 | 3 | 3 | 0 |
| TNFAIP2_ENST00000333007 | TNFAIP2 | Q03169 | Tumor necrosis factor alpha-induced protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 58 | 152 | 4 | 4 | 0 |
| TNPO1 | TNPO1 | Q92973 | Transportin-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 99 | 68 | 7 | 7 | 0 |
| TNPO3 | TNPO3 | Q9Y5L0 | Transportin-3 | chr7 | Not Cancer Driver | No | 1 | hippie | 122 | 12 | 1 | 1 | 1 |
| TOMM22 | TOMM22 | Q9NS69 | Mitochondrial import receptor subunit TOM22 homolog | chr22 | Not Cancer Driver | No | 1 | hippie | 18 | 83 | 9 | 9 | 0 |
| TTC27 | TTC27 | Q6P3X3 | Tetratricopeptide repeat protein 27 | chr2 | Not Cancer Driver | No | 1 | hippie | 109 | 40 | 5 | 5 | 0 |
| TTC37 | TTC37 | Q6PGP7 | Tetratricopeptide repeat protein 37 | chr5 | Not Cancer Driver | No | 1 | hippie | 164 | 59 | 3 | 3 | 3 |
| TTI1 | TTI1 | O43156 | TELO2-interacting protein 1 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 136 | 93 | 13 | 13 | 0 |
| TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
| TUBB8 | TUBB8 | Q3ZCM7 | Tubulin beta-8 chain | chr10 | Not Cancer Driver | No | 1 | hippie | 103 | 53 | 18 | 18 | 13 |
| TUBGCP2_ENST00000368563 | TUBGCP2 | Q9BSJ2 | Gamma-tubulin complex component 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 124 | 93 | 16 | 16 | 0 |
| TUBGCP3 | TUBGCP3 | Q96CW5 | Gamma-tubulin complex component 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 109 | 156 | 16 | 16 | 0 |
| TVP23C_ENST00000518321 | TVP23C | Q96ET8-3 | Isoform 3 of Golgi apparatus membrane protein TVP23 homolog C | chr17 | Not Cancer Driver | No | 1 | hippie | 18 | 16 | 1 | 1 | 0 |
| UBXN8 | UBXN8 | O00124 | UBX domain-containing protein 8 | chr8 | Not Cancer Driver | No | 1 | hippie | 25 | 116 | 14 | 14 | 0 |
| UCK2 | UCK2 | Q9BZX2 | Uridine-cytidine kinase 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 43 | 61 | 10 | 10 | 0 |
| UNC93B1 | UNC93B1 | Q9H1C4 | Protein unc-93 homolog B1 | chr11 | Not Cancer Driver | No | 1 | hippie | 57 | 127 | 5 | 5 | 0 |
| VAC14 | VAC14 | Q08AM6 | Protein VAC14 homolog | chr16 | Not Cancer Driver | No | 1 | hippie | 97 | 116 | 19 | 19 | 3 |
| VMP1 | VMP1 | Q96GC9 | Vacuole membrane protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 57 | 68 | 11 | 11 | 0 |
| VPS4A | VPS4A | Q9UN37 | Vacuolar protein sorting-associated protein 4A | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 167 | 17 | 17 | 4 |
| VPS51 | VPS51 | Q9UID3 | Vacuolar protein sorting-associated protein 51 homolog | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 150 | 11 | 11 | 1 |
| VRK2 | VRK2 | Q86Y07 | Serine/threonine-protein kinase VRK2 | chr2 | Not Cancer Driver | No | 1 | hippie | 63 | 126 | 15 | 15 | 0 |
| XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
| XPO5 | XPO5 | Q9HAV4 | Exportin-5 | chr6 | Not Cancer Driver | No | 1 | hippie | 112 | 64 | 7 | 7 | 0 |
| XPO7 | XPO7 | Q9UIA9 | Exportin-7 | chr8 | Not Cancer Driver | No | 1 | hippie | 132 | 59 | 8 | 8 | 0 |
| XPOT | XPOT | O43592 | Exportin-T | chr12 | Not Cancer Driver | No | 1 | hippie | 114 | 0 | 0 | 0 | 0 |
| XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | Not Cancer Driver | No | 1 | hippie | 24 | 35 | 2 | 2 | 1 |
| XYLT2 | XYLT2 | Q9H1B5 | Xylosyltransferase 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 85 | 264 | 28 | 28 | 1 |
| ZW10 | ZW10 | O43264 | Centromere/kinetochore protein zw10 homolog | chr11 | Not Cancer Driver | No | 1 | hippie | 90 | 63 | 11 | 11 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|