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LURAP1 ,LURAP1 ,Q96LR2
  • Uniprot Accession= Q96LR2
  • Ensembl Transcript= ENST00000371980.3
  • Uniprot Name= LURAP1
  • Name= Leucine rich adaptor protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 103
  • Number of Interaction partner in hippie: 132
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 intact, hippie 56 361 38 38 0
ALMS1 ALMS1 Q8TCU4 Alstrom syndrome protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 537 3518 441 441 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 4 intact, hippie, biogrid 161 909 128 128 0
AMOTL1 AMOTL1 Q8IY63 Angiomotin-like protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 136 851 121 121 0
ANKRD26 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 Not Cancer Driver No 1 hippie, biogrid 224 1269 164 164 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 46 122 22 22 0
ASH1L_ENST00000368346 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 Not Cancer Driver No 1 hippie, biogrid 415 1858 256 256 1
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 Not Cancer Driver No 1 hippie, biogrid 554 424 67 67 0
ATP23 ATP23 Q9Y6H3 Mitochondrial inner membrane protease ATP23 homolog chr12 Not Cancer Driver No 1 hippie 26 25 3 3 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 Not Cancer Driver No 2 intact, hippie 12 111 11 11 0
C19orf66 SHFL Q9NUL5 Shiftless antiviral inhibitor of ribosomal frameshifting protein chr19 Not Cancer Driver No 1 intact 23 166 12 12 0
C1orf122 C1orf122 Q6ZSJ8 Uncharacterized protein C1orf122 chr1 Not Cancer Driver No 1 hippie, biogrid 6 110 6 6 0
C5orf34 C5orf34 Q96MH7 Uncharacterized protein C5orf34 chr5 Not Cancer Driver No 1 hippie, biogrid 67 107 15 15 0
CCDC112_ENST00000395557 CCDC112 Q8NEF3 Coiled-coil domain-containing protein 112 chr5 Not Cancer Driver No 2 hippie, biogrid 49 382 44 44 0
CCDC185 CCDC185 Q8N715 Coiled-coil domain-containing protein 185 chr1 Not Cancer Driver No 1 intact, hippie 99 590 94 94 0
CCDC77 CCDC77 Q9BR77 Coiled-coil domain-containing protein 77 chr12 Not Cancer Driver No 1 hippie, biogrid 54 203 14 14 0
CCDC92 CCDC92 Q53HC0 Coiled-coil domain-containing protein 92 chr12 Not Cancer Driver No 1 hippie, biogrid 60 299 49 49 0
CCHCR1_ENST00000376266 CCHCR1 Q8TD31 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 116 565 88 88 0
CCP110 CCP110 O43303 Centriolar coiled-coil protein of 110 kDa chr16 Not Cancer Driver No 1 biogrid 94 679 61 61 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 1 hippie, biogrid 215 717 80 80 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 Not Cancer Driver No 2 hippie, biogrid 185 696 92 92 0
CDC42BPG CDC42BPG Q6DT37 Serine/threonine-protein kinase MRCK gamma chr11 Not Cancer Driver No 1 hippie, biogrid 166 736 79 79 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 Not Cancer Driver No 1 hippie, biogrid 217 1136 128 128 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 intact, hippie 59 132 16 16 2
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 Not Cancer Driver No 1 hippie, biogrid 230 1119 135 135 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie 33 198 17 17 3
DOCK10 DOCK10 Q96BY6 Dedicator of cytokinesis protein 10 chr2 Not Cancer Driver No 1 hippie 368 409 58 58 0
DTNB DTNB O60941 Dystrobrevin beta chr2 Not Cancer Driver No 1 intact, hippie 75 337 42 42 0
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 144 702 69 69 0
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 60 19 4 4 0
EMILIN3 EMILIN3 Q9NT22 EMILIN-3 chr20 Not Cancer Driver No 1 hippie, biogrid 97 337 40 40 0
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 40 307 34 34 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 Not Cancer Driver No 1 hippie, biogrid 95 583 67 67 0
EXOC5 EXOC5 O00471 Exocyst complex component 5 chr14 Not Cancer Driver No 1 hippie, biogrid 59 57 4 4 0
EXOC6B_ENST00000272427 EXOC6B Q9Y2D4 Exocyst complex component 6B chr2 Not Cancer Driver No 1 hippie, biogrid 107 167 21 21 0
FAAP100 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 hippie 93 207 31 31 0
FAM208A_ENST00000355628 TASOR Q9UK61 Protein TASOR chr3 Not Cancer Driver No 1 hippie 150 776 68 68 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FKBP15 FKBP15 Q5T1M5 FK506-binding protein 15 chr9 Not Cancer Driver No 1 hippie, biogrid 112 895 83 83 0
FNBP4 FNBP4 Q8N3X1 Formin-binding protein 4 chr11 Not Cancer Driver No 1 hippie, biogrid 119 926 106 106 0
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 Not Cancer Driver No 1 hippie, biogrid 121 42 8 8 0
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 111 276 6 6 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 76 316 28 28 2
GTPBP6 GTPBP6 O43824 Putative GTP-binding protein 6 chrX Not Cancer Driver No 1 hippie, biogrid 32 117 0 0 0
HAUS1 HAUS1 Q96CS2 HAUS augmin-like complex subunit 1 chr18 Not Cancer Driver No 2 intact, hippie 47 60 11 11 0
HAUS3 HAUS3 Q68CZ6 HAUS augmin-like complex subunit 3 chr4 Not Cancer Driver No 1 hippie, biogrid 61 55 7 7 0
HAUS5 HAUS5 O94927 HAUS augmin-like complex subunit 5 chr19 Not Cancer Driver No 1 hippie, biogrid 78 182 20 20 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 109 528 74 74 0
HJURP HJURP Q8NCD3 Holliday junction recognition protein chr2 Not Cancer Driver No 1 hippie, biogrid 108 572 85 85 0
HMG20A HMG20A Q9NP66 High mobility group protein 20A chr15 Not Cancer Driver No 1 hippie 58 308 44 44 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 107 16 4 4 18
HSBP1_ENST00000570259 HSBP1 O75506 Heat shock factor-binding protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 6 76 6 6 0
HSF2 HSF2 Q03933 Heat shock factor protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 64 292 37 37 0
IDE IDE P14735 Insulin-degrading enzyme chr10 Not Cancer Driver No 1 hippie, biogrid 90 96 8 8 0
IFFO2 IFFO2 Q5TF58 Intermediate filament family orphan 2 chr1 Not Cancer Driver No 1 hippie, biogrid 20 352 12 12 0
IFT57 IFT57 Q9NWB7 Intraflagellar transport protein 57 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 46 219 18 18 0
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 141 610 97 97 2
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 Census Yes 1 hippie, biogrid 97 327 47 47 0
KIF3A_ENST00000378746 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 Not Cancer Driver No 1 hippie, biogrid 92 409 59 59 0
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 Not Cancer Driver No 1 hippie, biogrid 150 844 104 104 5
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 57 308 38 38 2
KRT3 KRT3 P12035 Keratin, type II cytoskeletal 3 chr12 Not Cancer Driver No 1 intact, hippie 119 218 38 38 2
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 hippie, biogrid 341 2317 259 259 0
MICU2 MICU2 Q8IYU8 Calcium uptake protein 2, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 45 10 1 1 0
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 Not Cancer Driver No 1 hippie, biogrid 287 858 122 122 0
MPHOSPH9_ENST00000541076 MPHOSPH9 A0A8I5IG87 M-phase phosphoprotein 9 chr12 Not Cancer Driver No 1 hippie, biogrid 125 943 92 92 0
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 70 61 2 2 1
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie, biogrid 126 61 6 6 0
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 Census, Compendium Yes 1 hippie, biogrid 224 497 58 58 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 hippie, biogrid 204 394 43 43 0
MYO9A MYO9A B2RTY4 Unconventional myosin-IXa chr15 Not Cancer Driver No 1 hippie, biogrid 323 970 131 131 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 Not Cancer Driver No 1 hippie, biogrid 126 463 60 60 4
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie, biogrid 69 252 26 26 16
NUF2_ENST00000367900 NUF2 Q9BZD4 Kinetochore protein Nuf2 chr1 Not Cancer Driver No 1 hippie, biogrid 97 74 20 20 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie, biogrid 129 476 58 58 5
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 Not Cancer Driver No 1 hippie 66 82 12 12 2
PATJ PATJ Q8NI35 InaD-like protein chr1 Not Cancer Driver No 1 hippie 261 918 142 142 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie, biogrid 29 142 11 11 0
PDZRN3 PDZRN3 Q9UPQ7 E3 ubiquitin-protein ligase PDZRN3 chr3 Not Cancer Driver No 1 hippie, biogrid 234 699 195 195 0
PHF21A PHF21A Q96BD5 PHD finger protein 21A chr11 Not Cancer Driver No 1 hippie, biogrid 83 546 68 68 0
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 Not Cancer Driver No 1 hippie, biogrid 99 392 49 49 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 hippie, biogrid 181 133 32 32 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie, biogrid 107 97 8 8 0
PLEKHG4 PLEKHG4 Q58EX7 Puratrophin-1 chr16 Not Cancer Driver No 1 hippie, biogrid 132 295 35 35 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 hippie, biogrid 155 113 17 17 15
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 Not Cancer Driver No 1 hippie, biogrid 64 178 13 13 4
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 58 213 17 17 2
RBM14-RBM4 RBM14-RBM4 Q96PK6-5 Isoform 5 of RNA-binding protein 14 chr11 Not Cancer Driver No 1 biogrid 41 93 8 8 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie, biogrid 138 608 71 71 1
REXO5 REXO5 Q96IC2 RNA exonuclease 5 chr16 Not Cancer Driver No 1 hippie 89 101 12 12 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 Not Cancer Driver No 1 hippie, biogrid 132 645 80 80 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 145 732 81 81 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 hippie, biogrid 14 29 4 4 0
SALL2 SALL2 Q9Y467 Sal-like protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 136 820 117 117 0
SAP130_ENST00000259235 SAP130 Q9H0E3 Histone deacetylase complex subunit SAP130 chr2 Not Cancer Driver No 1 hippie, biogrid 119 940 107 107 0
SBF1_ENST00000348911 SBF1 O95248 Myotubularin-related protein 5 chr22 Not Cancer Driver No 1 hippie, biogrid 210 632 63 63 2
SENP5 SENP5 Q96HI0 Sentrin-specific protease 5 chr3 Not Cancer Driver No 1 hippie, biogrid 85 293 34 34 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 Not Cancer Driver No 1 hippie, biogrid 342 1240 156 156 20
SNAP29 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 Not Cancer Driver No 2 hippie, biogrid 21 246 20 20 0
SNAP47_ENST00000366759 SNAP47 Q5SQN1 Synaptosomal-associated protein 47 chr1 Not Cancer Driver No 1 hippie, biogrid 51 192 20 20 0
SNTB1 SNTB1 Q13884 Beta-1-syntrophin chr8 Not Cancer Driver No 1 hippie, biogrid 74 189 25 25 0
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 Not Cancer Driver No 1 hippie, biogrid 136 636 83 83 0
SPATS2L_ENST00000409140 SPATS2L Q9NUQ6 SPATS2-like protein chr2 Not Cancer Driver No 1 hippie, biogrid 69 428 53 53 0
SPATS2_ENST00000552918 SPATS2 Q86XZ4 Spermatogenesis-associated serine-rich protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 62 392 52 52 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 78 211 24 24 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 1 hippie, biogrid 62 412 27 27 0
TBC1D2B TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 Not Cancer Driver No 1 hippie, biogrid 118 419 43 43 0
TCEANC_ENST00000380600 TCEANC Q8N8B7 Transcription elongation factor A N-terminal and central domain-containing protein chrX Not Cancer Driver No 1 hippie 38 138 12 12 0
TEDC2 TEDC2 Q7L2K0 Tubulin epsilon and delta complex protein 2 chr16 Not Cancer Driver No 1 hippie 46 253 26 26 0
TGS1 TGS1 Q96RS0 Trimethylguanosine synthase chr8 Not Cancer Driver No 1 hippie, biogrid 100 483 56 56 0
THAP7_ENST00000399133 THAP7 Q9BT49 THAP domain-containing protein 7 chr22 Not Cancer Driver No 2 intact, hippie 34 214 24 24 0
TIGD5 TIGD5 Q53EQ6 Tigger transposable element-derived protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 43 347 19 19 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 85 625 83 83 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 43 316 36 36 0
TP53BP2 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 152 868 118 118 0
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 2 intact, hippie 35 230 27 27 21
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 hippie, biogrid 120 537 61 61 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie, biogrid 82 87 10 10 3
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie, biogrid 119 492 60 60 3
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 hippie, biogrid 135 732 78 78 11
TSPYL1 TSPYL1 Q9H0U9 Testis-specific Y-encoded-like protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 48 239 31 31 0
TTC3_ENST00000355666 TTC3 P53804 E3 ubiquitin-protein ligase TTC3 chr21 Not Cancer Driver No 1 hippie, biogrid 255 723 83 83 0
TXLNB TXLNB Q8N3L3 Beta-taxilin chr6 Not Cancer Driver No 4 intact, hippie, biogrid 131 546 115 115 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 intact, hippie 78 191 28 28 0
UTRN UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 hippie, biogrid 476 1283 183 183 0
VPS51 VPS51 Q9UID3 Vacuolar protein sorting-associated protein 51 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 75 150 11 11 1
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie, biogrid 51 489 49 49 0
ZDBF2 ZDBF2 Q9HCK1 DBF4-type zinc finger-containing protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 510 1664 380 380 0
ZNF324 ZNF324 O75467 Zinc finger protein 324A chr19 Not Cancer Driver No 1 hippie, biogrid 78 282 38 38 0
ZNF417 ZNF417 Q8TAU3 Zinc finger protein 417 chr19 Not Cancer Driver No 1 intact, hippie 76 156 23 23 0
ZNF445_ENST00000425708 ZNF445 P59923 Zinc finger protein 445 chr3 Not Cancer Driver No 1 hippie, biogrid 136 398 61 61 0
ZNF518A ZNF518A Q6AHZ1 Zinc finger protein 518A chr10 Not Cancer Driver No 1 hippie, biogrid 151 717 80 80 0
ZNF821 ZNF821 O75541 Zinc finger protein 821 chr16 Not Cancer Driver No 1 intact, hippie 49 294 36 36 0
ZNF865 ZNF865 P0CJ78 Zinc finger protein 865 chr19 Not Cancer Driver No 1 hippie, biogrid 3 504 2 2 0