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LCK ,LCK ,P06239
  • Uniprot Accession= P06239
  • Ensembl Transcript= ENST00000336890.9
  • Uniprot Name= LCK
  • Name= Tyrosine-protein kinase Lck
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 234
  • Number of Interaction partner in hippie: 435
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 2 hippie, biogrid 55 360 39 39 0
ACBD3 ACBD3 Q9H3P7 Golgi resident protein GCP60 chr1 Not Cancer Driver No 1 hippie, biogrid 59 350 40 40 0
ACP1_ENST00000272065 ACP1 P24666 Low molecular weight phosphotyrosine protein phosphatase chr2 Not Cancer Driver No 1 hippie 28 13 2 2 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 Not Cancer Driver No 1 hippie 88 156 20 20 4
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 Not Cancer Driver No 1 hippie 104 213 29 29 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 72 162 10 10 22
AHNAK2 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie, biogrid 1074 5470 1018 1018 0
AIP AIP O00170 AH receptor-interacting protein chr11 Not Cancer Driver No 1 hippie, biogrid 32 64 9 9 1
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 Compendium Yes 1 hippie 45 307 13 13 0
AKAP2_ENST00000259318 AKAP2 Q9Y2D5 A-kinase anchor protein 2 chr9 Not Cancer Driver No 1 hippie 137 852 134 134 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 161 909 128 128 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 860 3054 579 579 0
ANKRD26 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 Not Cancer Driver No 1 hippie, biogrid 224 1269 164 164 0
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 Not Cancer Driver No 1 hippie, biogrid 95 188 12 12 0
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 1 hippie, biogrid 138 404 59 59 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 1 hippie, biogrid 45 19 1 1 0
AP3S1 AP3S1 Q92572 AP-3 complex subunit sigma-1 chr5 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ARAP2 ARAP2 Q8WZ64 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 289 449 86 86 0
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 Not Cancer Driver No 1 hippie 123 547 72 72 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie, biogrid 242 1612 204 204 0
ARHGAP32 ARHGAP32 A7KAX9 Rho GTPase-activating protein 32 chr11 Not Cancer Driver No 1 hippie, biogrid 268 1476 193 193 0
ARL13B ARL13B Q3SXY8 ADP-ribosylation factor-like protein 13B chr3 Not Cancer Driver No 1 hippie, biogrid 62 251 40 40 3
ASB9 ASB9 Q96DX5 Ankyrin repeat and SOCS box protein 9 chrX Not Cancer Driver No 1 intact, hippie 55 71 20 20 0
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 143 293 42 42 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie, biogrid 51 63 8 8 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 168 341 64 64 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie 17 112 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie, biogrid 57 571 57 57 7
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 39 227 39 39 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 Census Yes 1 hippie 44 259 23 23 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 hippie, biogrid 94 75 21 21 0
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX Not Cancer Driver No 1 hippie 106 172 27 27 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
C1QTNF2 C1QTNF2 A0A499FIM1 C1q and tumor necrosis factor related protein 2 chr5 Not Cancer Driver No 1 intact, hippie 58 169 38 38 0
CABLES1 CABLES1 Q8TDN4 CDK5 and ABL1 enzyme substrate 1 chr18 Not Cancer Driver No 1 hippie, biogrid 58 334 23 23 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 27 92 10 10 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 Not Cancer Driver No 1 hippie 171 537 87 87 0
CASKIN2 CASKIN2 Q8WXE0 Caskin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 113 782 79 79 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 Census Yes 1 hippie 160 562 104 104 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 96 505 91 91 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 1 hippie, biogrid 226 1481 173 173 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 Not Cancer Driver No 1 hippie 107 0 0 0 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 2 hippie, biogrid 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 hippie 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie 83 72 10 10 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie 66 5 1 1 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie 59 36 6 6 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 hippie 41 36 2 2 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 Not Cancer Driver No 1 hippie 75 126 35 35 0
CD247 CD247 P20963 T-cell surface glycoprotein CD3 zeta chain chr1 Not Cancer Driver No 1 hippie 33 91 24 24 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 Census Yes 1 hippie 42 18 10 10 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 Not Cancer Driver No 1 hippie 54 3 1 1 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 Not Cancer Driver No 1 hippie 28 72 12 12 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie 69 56 11 11 0
CD44 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 1 hippie 75 542 60 60 0
CD48_ENST00000368046 CD48 P09326 CD48 antigen chr1 Not Cancer Driver No 1 hippie 39 2 0 0 0
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 Not Cancer Driver No 1 hippie 67 146 19 19 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 Not Cancer Driver No 1 hippie 45 128 13 13 1
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 Census Yes 1 hippie 32 28 3 3 0
CD79B_ENST00000006750 CD79B P40259 B-cell antigen receptor complex-associated protein beta chain chr17 Census, Compendium Yes 1 hippie 25 43 10 10 1
CD8A_ENST00000283635 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 Not Cancer Driver No 1 hippie 33 28 2 2 1
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 hippie 61 224 26 26 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 52 214 31 31 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 1 hippie, biogrid 215 717 80 80 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 Not Cancer Driver No 1 hippie, biogrid 185 696 92 92 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDC45_ENST00000407835 CDC45 O75419 Cell division control protein 45 homolog chr22 Not Cancer Driver No 1 hippie 73 66 16 16 5
CDCA3 CDCA3 Q99618 Cell division cycle-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 26 268 26 26 0
CDCP1 CDCP1 Q9H5V8 CUB domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 113 161 26 26 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 2 hippie, biogrid 40 1 0 0 0
CDK3_ENST00000448471 CDK3 Q00526 Cyclin-dependent kinase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 40 17 2 2 0
CDKAL1 CDKAL1 Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase chr6 Not Cancer Driver No 1 hippie 80 120 14 14 0
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 1 hippie, biogrid 59 264 26 26 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie, biogrid 96 540 72 72 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 47 119 17 17 0
CISH_ENST00000348721 CISH Q9NSE2 Cytokine-inducible SH2-containing protein chr3 Not Cancer Driver No 1 hippie 33 97 8 8 0
CNOT10_ENST00000328834 CNOT10 Q9H9A5 CCR4-NOT transcription complex subunit 10 chr3 Not Cancer Driver No 1 hippie, biogrid 69 218 18 18 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 Not Cancer Driver No 1 hippie, biogrid 36 71 2 2 0
COBLL1_ENST00000375458 COBLL1 Q53SF7 Cordon-bleu protein-like 1 chr2 Not Cancer Driver No 1 hippie, biogrid 165 951 150 150 0
COG1 COG1 Q8WTW3 Conserved oligomeric Golgi complex subunit 1 chr17 Not Cancer Driver No 1 hippie, biogrid 88 204 18 18 0
CRYBG3 CRYBG3 Q68DQ2 Very large A-kinase anchor protein chr3 Not Cancer Driver No 1 hippie, biogrid 179 1770 71 71 0
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 Not Cancer Driver No 1 hippie 204 541 120 120 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 Census, Compendium Yes 1 hippie 131 209 34 34 2
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie 41 18 1 1 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
CSTF2T CSTF2T Q9H0L4 Cleavage stimulation factor subunit 2 tau variant chr10 Not Cancer Driver No 1 hippie, biogrid 87 507 75 75 0
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 Not Cancer Driver No 1 hippie 34 46 2 2 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 Not Cancer Driver No 1 hippie 37 3 0 0 1
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 126 268 35 35 4
CTNND1 CTNND1 O60716 Catenin delta-1 chr11 Census Yes 2 hippie, biogrid 154 570 83 83 0
CTNND2 CTNND2 Q9UQB3 Catenin delta-2 chr5 Census Yes 1 hippie 386 837 254 254 0
DAPP1 DAPP1 Q9UN19 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide chr4 Not Cancer Driver No 1 hippie 50 40 9 9 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 1 hippie, biogrid 113 458 52 52 0
DEF6 DEF6 Q9H4E7 Differentially expressed in FDCP 6 homolog chr6 Not Cancer Driver No 1 hippie 72 336 30 30 0
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 Not Cancer Driver No 1 hippie, biogrid 204 396 53 53 0
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 Not Cancer Driver No 1 hippie, biogrid 181 375 49 49 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 1 hippie 120 460 67 67 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 Not Cancer Driver No 1 hippie, biogrid 230 1119 135 135 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie 37 153 16 16 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie, biogrid 50 174 27 27 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie, biogrid 41 102 9 9 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 138 270 43 43 22
DOK1 DOK1 Q99704 Docking protein 1 chr2 Not Cancer Driver No 1 hippie 50 294 31 31 0
DOK2 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 1 hippie 58 254 31 31 0
DOK3 DOK3 Q7L591 Docking protein 3 chr5 Not Cancer Driver No 1 hippie 61 281 37 37 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 35 31 0 0 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 Not Cancer Driver No 1 hippie, biogrid 192 257 61 61 5
DSG2 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie, biogrid 173 476 68 68 5
DSP DSP P15924 Desmoplakin chr6 Not Cancer Driver No 1 hippie 483 1124 204 204 6
DSTN DSTN P60981 Destrin chr20 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
DST_ENST00000370788 DST Q03001-14 Isoform 9 of Dystonin chr6 Not Cancer Driver No 1 hippie, biogrid 729 1895 241 241 0
DTNA_ENST00000444659 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 hippie, biogrid 162 412 86 86 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 Not Cancer Driver No 1 hippie 122 554 70 70 0
EDRF1 EDRF1 Q3B7T1 Erythroid differentiation-related factor 1 chr10 Not Cancer Driver No 1 hippie, biogrid 139 270 36 36 0
EEF1B2_ENST00000236957 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie 63 71 11 11 0
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 44 66 5 5 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie 111 78 14 14 1
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 Not Cancer Driver No 1 hippie, biogrid 42 97 15 15 0
EFR3A EFR3A Q14156 Protein EFR3 homolog A chr8 Not Cancer Driver No 1 hippie, biogrid 114 77 10 10 0
EFR3B EFR3B Q9Y2G0 Protein EFR3 homolog B chr2 Not Cancer Driver No 1 hippie, biogrid 42 104 3 3 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 444 223 35 35 1
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 Not Cancer Driver No 1 hippie, biogrid 35 206 8 8 2
EIF4A1 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 1 hippie 48 35 7 7 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPB41L1 EPB41L1 Q9H4G0 Band 4.1-like protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 151 577 109 109 1
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1 hippie, biogrid 298 695 207 207 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 97 312 45 45 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie, biogrid 171 187 39 39 3
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 hippie, biogrid 428 323 116 116 2
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 Not Cancer Driver No 1 hippie 167 967 118 118 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 30 34 2 2 3
EXOC3_ENST00000315013 EXOC3 O60645 Exocyst complex component 3 chr5 Not Cancer Driver No 1 hippie, biogrid 102 124 19 19 0
EXOC4 EXOC4 Q96A65 Exocyst complex component 4 chr7 Not Cancer Driver No 1 hippie, biogrid 164 133 33 33 0
EXOC5 EXOC5 O00471 Exocyst complex component 5 chr14 Not Cancer Driver No 1 hippie, biogrid 59 57 4 4 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie 66 295 35 35 0
FAM166B FAM166B A8MTA8 Protein FAM166B chr9 Not Cancer Driver No 1 intact, hippie 27 140 14 14 0
FAM171A1 FAM171A1 Q5VUB5 Protein FAM171A1 chr10 Not Cancer Driver No 1 hippie, biogrid 191 525 123 123 0
FAM171A2 FAM171A2 A8MVW0 Protein FAM171A2 chr17 Not Cancer Driver No 1 hippie, biogrid 13 478 4 4 0
FAM171B FAM171B Q6P995 Protein FAM171B chr2 Not Cancer Driver No 1 hippie, biogrid 154 401 78 78 0
FAM174A FAM174A Q8TBP5 Membrane protein FAM174A chr5 Not Cancer Driver No 1 hippie 27 140 21 21 0
FARP1_ENST00000319562 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 147 315 60 60 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 Census, Compendium Yes 1 hippie 55 62 18 18 22
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 Not Cancer Driver No 1 hippie 65 94 18 18 1
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 Not Cancer Driver No 1 hippie 69 0 0 0 1
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 Not Cancer Driver No 1 hippie, biogrid 71 101 10 10 0
FGD1 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 139 520 74 74 5
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 46 134 12 12 0
FLII FLII Q13045 Protein flightless-1 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 128 206 32 32 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 56 20 3 3 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 1 hippie 200 64 27 27 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 614 1322 475 475 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 1 hippie, biogrid 69 415 58 58 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 79 570 68 68 1
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 Census, Compendium Yes 1 hippie 111 364 87 87 2
GCC2 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 178 999 113 113 0
GLMN GLMN Q92990 Glomulin chr1 Not Cancer Driver No 1 hippie, biogrid 49 37 6 6 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie, biogrid 115 854 96 96 0
GOLGA3_ENST00000450791 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 221 1272 189 189 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 231 1658 162 162 0
GOLGA5 GOLGA5 Q8TBA6 Golgin subfamily A member 5 chr14 Census Yes 1 hippie, biogrid 89 591 62 62 0
GOLGB1_ENST00000340645 GOLGB1 Q14789 Golgin subfamily B member 1 chr3 Not Cancer Driver No 1 hippie, biogrid 403 2416 300 300 0
GPRIN1 GPRIN1 Q7Z2K8 G protein-regulated inducer of neurite outgrowth 1 chr5 Not Cancer Driver No 1 hippie, biogrid 116 999 115 115 0
GPRIN3_ENST00000333209 GPRIN3 Q6ZVF9 G protein-regulated inducer of neurite outgrowth 3 chr4 Not Cancer Driver No 1 hippie, biogrid 141 749 138 138 0
GRAP GRAP Q13588 GRB2-related adapter protein chr17 Not Cancer Driver No 1 hippie 10 0 0 0 1
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 Not Cancer Driver No 1 hippie 69 17 2 2 3
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 hippie, biogrid 112 124 25 25 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 intact, hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 2 intact, hippie 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 Compendium Yes 1 hippie 55 50 6 6 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 6 301 6 6 22
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 Not Cancer Driver No 1 hippie 81 182 33 33 1
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie, biogrid 297 798 203 203 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 hippie 139 43 10 10 1
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 167 63 10 10 7
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 131 421 89 89 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie, biogrid 112 241 37 37 0
KALRN_ENST00000360013 KALRN O60229 Kalirin chr3 Not Cancer Driver No 1 hippie, biogrid 544 732 128 128 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie 53 362 43 43 0
KIAA1217 KIAA1217 Q5T5P2 Sickle tail protein homolog chr10 Not Cancer Driver No 1 hippie, biogrid 362 1743 328 328 0
KIAA1522_ENST00000373480 KIAA1522 Q9P206 Uncharacterized protein KIAA1522 chr1 Not Cancer Driver No 1 hippie, biogrid 143 1007 140 140 0
KIAA1549 KIAA1549 Q9HCM3 UPF0606 protein KIAA1549 chr7 Census Yes 1 hippie, biogrid 295 1129 169 169 0
KIAA1671_ENST00000406486 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 1 hippie, biogrid 14 1759 14 14 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie, biogrid 245 683 113 113 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF16B_ENST00000354981 KIF16B Q96L93 Kinesin-like protein KIF16B chr20 Not Cancer Driver No 1 hippie, biogrid 248 436 74 74 0
KIR2DL3 KIR2DL3 P43628 Killer cell immunoglobulin-like receptor 2DL3 chr19 Not Cancer Driver No 1 hippie 62 129 29 29 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 2 hippie, biogrid 226 83 33 33 21
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 Not Cancer Driver No 1 hippie 37 213 29 29 0
LAX1 LAX1 Q8IWV1 Lymphocyte transmembrane adapter 1 chr1 Not Cancer Driver No 1 hippie 61 228 32 32 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LCP2 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 Not Cancer Driver No 1 hippie 107 390 80 80 0
LIME1 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 Not Cancer Driver No 1 hippie 22 193 17 17 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie, biogrid 101 265 12 12 0
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 Not Cancer Driver No 1 hippie, biogrid 211 1018 141 141 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 1 hippie, biogrid 89 330 42 42 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 2 hippie, biogrid 95 84 12 12 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 2 hippie, biogrid 78 508 66 66 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 Not Cancer Driver No 1 hippie, biogrid 877 2826 334 334 4
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 1
MAP3K21 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 1 hippie 191 658 112 112 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 143 649 55 55 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie, biogrid 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie, biogrid 92 376 49 49 1
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 Not Cancer Driver No 1 hippie 36 31 4 4 0
MED25 MED25 Q71SY5 Mediator of RNA polymerase II transcription subunit 25 chr19 Not Cancer Driver No 1 hippie 103 432 54 54 2
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 1 hippie 24 101 18 18 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 226 62 15 15 19
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 113 740 56 56 0
MPP7 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 Not Cancer Driver No 1 hippie, biogrid 132 199 72 72 0
MPRIP_ENST00000341712 MPRIP Q6WCQ1 Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 1 hippie, biogrid 118 735 95 95 0
MS4A1_ENST00000345732 MS4A1 P11836 B-lymphocyte antigen CD20 chr11 Not Cancer Driver No 1 hippie 73 83 23 23 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 Census Yes 1 hippie 40 1050 19 19 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 1 hippie, biogrid 144 34 4 4 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 hippie, biogrid 110 66 11 11 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie, biogrid 126 61 6 6 0
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 Census, Compendium Yes 1 hippie, biogrid 224 497 58 58 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie, biogrid 176 342 41 41 3
NCKAP5L NCKAP5L Q9HCH0 Nck-associated protein 5-like chr12 Not Cancer Driver No 1 hippie, biogrid 169 1292 164 164 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 Not Cancer Driver No 1 hippie 106 516 72 72 0
NF1 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 2 hippie, biogrid 375 406 47 47 85
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 hippie 37 102 9 9 1
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 intact, hippie 47 124 20 20 0
NISCH_ENST00000479054 NISCH Q9Y2I1 Nischarin chr3 Not Cancer Driver No 1 hippie, biogrid 160 418 43 43 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 Not Cancer Driver No 1 hippie 74 662 69 69 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 Not Cancer Driver No 1 hippie, biogrid 94 255 53 53 1
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 282 630 77 77 1
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie, biogrid 29 249 22 22 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 Not Cancer Driver No 1 hippie 66 101 1 1 5
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NUDC NUDC Q9Y266 Nuclear migration protein nudC chr1 Not Cancer Driver No 1 hippie, biogrid 36 235 29 29 0
NUDCD3 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 hippie, biogrid 30 199 16 16 0
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 42 467 23 23 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie, biogrid 70 490 58 58 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie, biogrid 151 126 24 24 41
PAG1 PAG1 Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 chr8 Not Cancer Driver No 1 hippie 58 394 54 54 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie 89 242 49 49 0
PALM PALM O75781 Paralemmin-1 chr19 Not Cancer Driver No 1 hippie, biogrid 50 381 50 50 0
PALM2_ENST00000374531 PALM2 Q8IXS6 Paralemmin-2 chr9 Not Cancer Driver No 1 hippie, biogrid 64 334 56 56 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 200 1144 170 170 2
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 1 hippie, biogrid 222 1232 150 150 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 2 153 2 2 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 Not Cancer Driver No 1 hippie, biogrid 91 29 4 4 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 Not Cancer Driver No 1 hippie, biogrid 80 70 8 8 9
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 Not Cancer Driver No 1 hippie, biogrid 133 43 10 10 0
PHACTR4_ENST00000373839 PHACTR4 Q8IZ21 Phosphatase and actin regulator 4 chr1 Not Cancer Driver No 1 hippie, biogrid 80 679 76 76 0
PHLDB3 PHLDB3 Q6NSJ2 Pleckstrin homology-like domain family B member 3 chr19 Not Cancer Driver No 1 hippie, biogrid 74 462 50 50 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 2 hippie, biogrid 267 142 11 11 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 30 157 13 13 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 2 hippie, biogrid 154 268 61 61 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 96 418 47 47 3
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 Not Cancer Driver No 1 hippie, biogrid 99 392 49 49 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 176 434 98 98 8
PKP4 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 1 hippie, biogrid 172 756 119 119 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PLCH1 PLCH1 Q4KWH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 chr3 Not Cancer Driver No 1 hippie, biogrid 383 772 195 195 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie 107 97 8 8 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 hippie, biogrid 144 869 114 114 0
PLEKHA6 PLEKHA6 Q9Y2H5 Pleckstrin homology domain-containing family A member 6 chr1 Not Cancer Driver No 1 hippie, biogrid 172 973 154 154 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 hippie, biogrid 152 919 121 121 0
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie, biogrid 164 865 126 126 0
PPFIBP1 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie, biogrid 110 555 57 57 0
PPID PPID Q08752 Peptidyl-prolyl cis-trans isomerase D chr4 Not Cancer Driver No 1 hippie, biogrid 36 94 9 9 0
PPP1R13B PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 115 821 92 92 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 Compendium Yes 1 hippie 79 43 9 9 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 Not Cancer Driver No 1 hippie 147 28 9 9 0
PRPF4B PRPF4B Q13523 Serine/threonine-protein kinase PRP4 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 120 646 86 86 0
PSD3_ENST00000440756 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 146 645 94 94 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 Not Cancer Driver No 1 hippie 161 261 37 37 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 2 intact, hippie 134 425 55 55 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie 129 260 38 38 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 Not Cancer Driver No 1 hippie 102 516 60 60 0
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 hippie, biogrid 299 1231 149 149 0
PTPN14 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie, biogrid 173 582 99 99 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 Not Cancer Driver No 1 hippie 141 364 62 62 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 hippie 73 192 25 25 0
PTPRB_ENST00000261266 PTPRB P23467 Receptor-type tyrosine-protein phosphatase beta chr12 Census, Compendium Yes 1 hippie 425 302 65 65 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 Census, Compendium Yes 1 hippie 315 462 107 107 0
PTPRCAP PTPRCAP Q14761 Protein tyrosine phosphatase receptor type C-associated protein chr11 Not Cancer Driver No 1 hippie 21 120 16 16 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 Not Cancer Driver No 1 hippie 268 696 96 96 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 Not Cancer Driver No 1 hippie 212 465 61 61 0
PTPRH PTPRH Q9HD43 Receptor-type tyrosine-protein phosphatase H chr19 Not Cancer Driver No 1 hippie 228 474 74 74 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 Not Cancer Driver No 1 hippie 184 401 61 61 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 Census, Compendium Yes 1 hippie 292 302 57 57 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 Not Cancer Driver No 1 hippie 256 365 60 60 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 204 137 34 34 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 Not Cancer Driver No 1 hippie 480 978 216 216 0
PTS PTS Q03393 6-pyruvoyl tetrahydrobiopterin synthase chr11 Not Cancer Driver No 1 hippie 9 22 1 1 24
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 62 341 24 24 0
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 145 1118 133 133 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 hippie 89 169 38 38 22
RAI14_ENST00000503673 RAI14 Q9P0K7 Ankycorbin chr5 Not Cancer Driver No 1 hippie, biogrid 117 693 78 78 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 1 hippie, biogrid 164 606 86 86 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX Not Cancer Driver No 1 hippie 22 134 18 18 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX Not Cancer Driver No 1 hippie 82 380 81 81 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 Not Cancer Driver No 1 hippie 77 371 75 75 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie, biogrid 212 366 50 50 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 137 417 61 61 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie, biogrid 203 299 71 71 5
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 Not Cancer Driver No 1 intact, hippie 107 87 22 22 1
RP9 RP9 Q8TA86 Retinitis pigmentosa 9 protein chr7 Not Cancer Driver No 1 hippie 26 206 23 23 2
RPL15_ENST00000413699 RPL15 P61313 60S ribosomal protein L15 chr3 Not Cancer Driver No 1 hippie, biogrid 18 84 9 9 0
RPL22L1 RPL22L1 Q6P5R6 60S ribosomal protein L22-like 1 chr3 Not Cancer Driver No 1 hippie 16 22 4 4 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie, biogrid 27 100 5 5 0
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 hippie, biogrid 18 6 0 0 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 hippie, biogrid 23 81 7 7 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 hippie, biogrid 23 34 5 5 0
SAFB_ENST00000292123 SAFB Q15424 Scaffold attachment factor B1 chr19 Not Cancer Driver No 1 hippie 111 911 110 110 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 hippie, biogrid 196 1064 135 135 2
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 Census, Compendium Yes 1 hippie 48 333 19 19 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX Not Cancer Driver No 1 hippie 40 24 8 8 19
SH2D2A_ENST00000368199 SH2D2A Q9NP31 SH2 domain-containing protein 2A chr1 Not Cancer Driver No 1 hippie 51 272 42 42 0
SH3BP2_ENST00000435136 SH3BP2 P78314 SH3 domain-binding protein 2 chr4 Not Cancer Driver No 1 hippie 71 356 43 43 7
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SIPA1L2 SIPA1L2 Q9P2F8 Signal-induced proliferation-associated 1-like protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 311 895 172 172 0
SIT1 SIT1 Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 chr9 Not Cancer Driver No 1 hippie 21 122 9 9 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 Not Cancer Driver No 1 hippie 67 130 27 27 0
SKAP2 SKAP2 O75563 Src kinase-associated phosphoprotein 2 chr7 Not Cancer Driver No 1 hippie 51 157 19 19 0
SLAMF6 SLAMF6 Q96DU3 SLAM family member 6 chr1 Not Cancer Driver No 1 hippie 69 60 14 14 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 141 297 18 18 8
SLC25A18 SLC25A18 Q9H1K4 Mitochondrial glutamate carrier 2 chr22 Not Cancer Driver No 1 hippie 54 21 1 1 0
SLC25A22_ENST00000628067 SLC25A22 Q9H936 Mitochondrial glutamate carrier 1 chr11 Not Cancer Driver No 1 hippie 34 22 2 2 1
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 hippie 41 0 0 0 0
SLC30A6_ENST00000282587 SLC30A6 Q6NXT4 Zinc transporter 6 chr2 Not Cancer Driver No 1 hippie, biogrid 54 93 7 7 0
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 62 171 12 12 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 89 256 31 31 0
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 hippie, biogrid 18 179 16 16 0
SNTB2 SNTB2 Q13425 Beta-2-syntrophin chr16 Not Cancer Driver No 1 hippie, biogrid 28 163 3 3 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie, biogrid 33 85 7 7 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 hippie 22 66 3 3 2
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 Not Cancer Driver No 1 hippie 32 61 2 2 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 Not Cancer Driver No 1 hippie 27 111 14 14 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 Compendium Yes 1 hippie 197 458 62 62 38
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie, biogrid 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie, biogrid 311 869 123 123 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 Not Cancer Driver No 1 hippie, biogrid 317 877 126 126 2
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie, biogrid 53 130 11 11 1
ST13 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 297 29 29 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 1 hippie 131 144 25 25 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 1 hippie 89 125 14 14 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 74 270 39 39 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 Not Cancer Driver No 1 hippie 57 77 6 6 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie, biogrid 35 112 14 14 12
SUGT1 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 Not Cancer Driver No 1 hippie, biogrid 31 119 5 5 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 Census Yes 1 hippie 96 131 27 27 5
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 Not Cancer Driver No 1 hippie, biogrid 208 584 76 76 3
TANC1 TANC1 Q9C0D5 Protein TANC1 chr2 Not Cancer Driver No 1 hippie, biogrid 237 906 101 101 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 112 53 10 10 1
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie 54 55 10 10 0
THEMIS_ENST00000368250 THEMIS Q8N1K5 Protein THEMIS chr6 Not Cancer Driver No 1 hippie 208 111 34 34 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 Not Cancer Driver No 1 hippie 24 5 0 0 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 Not Cancer Driver No 1 hippie, biogrid 221 1712 219 219 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 18 83 9 9 0
TOMM34 TOMM34 Q15785 Mitochondrial import receptor subunit TOM34 chr20 Not Cancer Driver No 1 hippie, biogrid 32 113 15 15 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 Not Cancer Driver No 1 hippie 86 129 67 67 0
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 Not Cancer Driver No 1 intact, hippie 66 69 9 9 0
TRIO TRIO O75962 Triple functional domain protein chr5 Not Cancer Driver No 1 hippie, biogrid 400 1052 118 118 10
TRIP11 TRIP11 Q15643 Thyroid receptor-interacting protein 11 chr14 Census, Compendium Yes 1 hippie, biogrid 218 1364 161 161 2
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 Not Cancer Driver No 1 hippie 142 231 34 34 44
TTC1 TTC1 Q99614 Tetratricopeptide repeat protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 28 211 21 21 0
TTC4 TTC4 O95801 Tetratricopeptide repeat protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 45 100 12 12 0
TTC9C_ENST00000532583 TTC9C Q8N5M4 Tetratricopeptide repeat protein 9C chr11 Not Cancer Driver No 1 hippie, biogrid 15 81 3 3 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 hippie 52 65 11 11 2
TUB_ENST00000299506 TUB P50607 Tubby protein homolog chr11 Not Cancer Driver No 1 hippie 89 357 51 51 0
UBAP2 UBAP2 Q5T6F2 Ubiquitin-associated protein 2 chr9 Not Cancer Driver No 1 intact, hippie 108 1036 98 98 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 hippie 141 136 22 22 0
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 64 132 26 26 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 88 253 22 22 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 hippie 20 89 4 4 1
UNC45A UNC45A Q9H3U1 Protein unc-45 homolog A chr15 Not Cancer Driver No 1 hippie, biogrid 78 128 4 4 0
UQCRQ_ENST00000378665 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 1 hippie 9 12 1 1 1
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 hippie, biogrid 78 368 28 28 0
USP54 USP54 Q70EL1 Inactive ubiquitin carboxyl-terminal hydrolase 54 chr10 Not Cancer Driver No 1 hippie, biogrid 186 1268 143 143 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 Not Cancer Driver No 1 hippie, biogrid 113 472 81 81 0
UTRN UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 hippie, biogrid 476 1283 183 183 0
VANGL1 VANGL1 Q8TAA9 Vang-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 72 140 15 15 3
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 hippie 165 113 19 19 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX Census, Compendium Yes 1 hippie 75 400 55 55 30
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 Not Cancer Driver No 1 hippie 72 394 57 57 0
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 hippie, biogrid 166 105 13 13 0
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 103 70 15 15 4
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 hippie 87 118 11 11 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 Not Cancer Driver No 1 hippie 126 117 17 17 8
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie, biogrid 89 462 63 63 0