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ISG15 ,ISG15 ,P05161
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 20
  • Number of Interaction partner in hippie: 419
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAAS AAAS Q9NRG9 Aladin chr12 Not Cancer Driver No 1 hippie 58 116 12 12 3
ABCF2 ABCF2 Q9UG63 ATP-binding cassette sub-family F member 2 chr7 Not Cancer Driver No 1 hippie 112 153 20 20 0
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie 120 114 12 12 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 Not Cancer Driver No 1 hippie 43 52 7 7 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 hippie 73 29 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 Not Cancer Driver No 1 hippie 108 195 30 30 6
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 hippie 131 244 42 42 8
AHNAK AHNAK Q09666 Neuroblast differentiation-associated protein AHNAK chr11 Not Cancer Driver No 1 hippie 805 5777 794 794 0
AHNAK2 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie 1074 5470 1018 1018 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie 88 166 22 22 11
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 Not Cancer Driver No 1 hippie 31 161 19 19 0
AKR1B10 AKR1B10 O60218 Aldo-keto reductase family 1 member B10 chr7 Not Cancer Driver No 1 hippie 58 28 4 4 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 Not Cancer Driver No 1 hippie 32 1 0 0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 Not Cancer Driver No 1 hippie 49 11 1 1 0
ALDH1A1 ALDH1A1 P00352 Aldehyde dehydrogenase 1A1 chr9 Not Cancer Driver No 1 hippie 65 29 3 3 0
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 hippie 47 65 9 9 3
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 hippie 59 61 12 12 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 49 20 4 4 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 Not Cancer Driver No 1 hippie 53 22 4 4 0
ANXA5 ANXA5 P08758 Annexin A5 chr4 Not Cancer Driver No 1 hippie 50 33 5 5 0
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 Not Cancer Driver No 1 hippie 95 188 12 12 0
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 1 hippie 100 145 12 12 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 hippie 85 95 12 12 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 hippie 55 41 9 9 1
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 hippie 17 0 0 0 0
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 Not Cancer Driver No 1 hippie 162 769 95 95 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 Not Cancer Driver No 1 intact, hippie 26 0 0 0 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 1 hippie 279 87 8 8 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 Census Yes 1 hippie 74 25 1 1 1
ATL3 ATL3 Q6DD88 Atlastin-3 chr11 Not Cancer Driver No 1 intact, hippie 43 57 5 5 1
ATP13A1 ATP13A1 Q9HD20 Endoplasmic reticulum transmembrane helix translocase chr19 Not Cancer Driver No 1 hippie 131 95 15 15 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie 115 115 16 16 6
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie 136 78 14 14 41
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie 143 293 42 42 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATXN2L_ENST00000336783 ATXN2L Q8WWM7 Ataxin-2-like protein chr16 Not Cancer Driver No 1 hippie 135 1000 131 131 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 Not Cancer Driver No 1 hippie 146 1228 134 134 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 intact, hippie 37 104 14 14 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 Census, Compendium Yes 1 hippie 421 899 408 408 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 hippie, biogrid 94 75 21 21 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 Not Cancer Driver No 1 hippie 124 827 89 89 0
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 1 hippie 34 149 10 10 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie 14 103 6 6 2
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 hippie 287 368 52 52 1
CALD1 CALD1 Q05682 Caldesmon chr7 Not Cancer Driver No 1 hippie 133 793 133 133 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie 65 334 38 38 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 30 2 0 0 0
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 72 477 63 63 0
CCNL1 CCNL1 Q9UK58 Cyclin-L1 chr3 Not Cancer Driver No 1 hippie 58 281 38 38 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 hippie 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 hippie 51 92 2 2 0
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie 66 5 1 1 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 hippie 41 36 2 2 0
CDK3_ENST00000448471 CDK3 Q00526 Cyclin-dependent kinase 3 chr17 Not Cancer Driver No 1 hippie 40 17 2 2 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie 21 4 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CHD1 CHD1 O14646 Chromodomain-helicase-DNA-binding protein 1 chr5 Not Cancer Driver No 1 hippie 172 975 109 109 4
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 Not Cancer Driver No 1 hippie 24 195 18 18 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie 73 409 55 55 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 hippie 32 27 5 5 0
CLINT1_ENST00000411809 CLINT1 Q14677 Clathrin interactor 1 chr5 Not Cancer Driver No 1 hippie 61 475 51 51 0
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 Not Cancer Driver No 1 hippie 64 131 21 21 0
CLPTM1 CLPTM1 O96005 Cleft lip and palate transmembrane protein 1 chr19 Not Cancer Driver No 1 hippie 83 163 19 19 0
CLPTM1L CLPTM1L Q96KA5 Cleft lip and palate transmembrane protein 1-like protein chr5 Not Cancer Driver No 1 intact, hippie 83 38 4 4 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 hippie 163 157 18 18 4
COPB2 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 hippie 111 114 22 22 0
CSE1L CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie 109 32 5 5 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
DAB2 DAB2 P98082 Disabled homolog 2 chr5 Not Cancer Driver No 1 hippie 144 680 125 125 0
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 Not Cancer Driver No 1 hippie 7 0 0 0 0
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 Census, Compendium Yes 1 hippie 45 70 5 5 2
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie 34 13 3 3 1
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 hippie 82 91 15 15 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 Not Cancer Driver No 1 hippie 91 362 48 48 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 Not Cancer Driver No 1 hippie 121 426 71 71 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie 44 37 2 2 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 133 301 47 47 18
DDX42 DDX42 Q86XP3 ATP-dependent RNA helicase DDX42 chr17 Not Cancer Driver No 1 hippie 126 607 79 79 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 1 hippie 113 458 52 52 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DEPDC7 DEPDC7 Q96QD5 DEP domain-containing protein 7 chr11 Not Cancer Driver No 1 hippie 67 48 5 5 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 Not Cancer Driver No 1 intact, hippie 55 0 0 0 6
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 Not Cancer Driver No 1 hippie 85 7 1 1 53
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 hippie 110 180 30 30 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie 165 260 40 40 6
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie 182 331 42 42 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie 35 196 26 26 0
DNAJB4 DNAJB4 Q9UDY4 DnaJ homolog subfamily B member 4 chr1 Not Cancer Driver No 1 hippie 41 160 20 20 0
DPY19L1 DPY19L1 Q2PZI1 Probable C-mannosyltransferase DPY19L1 chr7 Not Cancer Driver No 1 hippie 86 26 0 0 0
DSG2 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie 173 476 68 68 5
DSTN DSTN P60981 Destrin chr20 Not Cancer Driver No 1 hippie 18 0 0 0 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 hippie 505 495 62 62 21
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 intact, hippie 30 9 0 0 9
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie 109 100 14 14 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie 74 121 17 17 3
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 44 66 5 5 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie 111 78 14 14 1
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie 59 188 22 22 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 1 hippie 229 1079 153 153 2
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELF3_ENST00000367283 ELF3 P78545 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 1 intact, hippie, biogrid 94 145 34 34 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
EPHX1_ENST00000366837 EPHX1 P07099 Epoxide hydrolase 1 chr1 Not Cancer Driver No 1 hippie 75 7 3 3 0
EPPK1 EPPK1 P58107 Epiplakin chr8 Not Cancer Driver No 1 hippie 417 1336 67 67 0
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 Census, Compendium Yes 1 hippie 150 5 0 0 35
ERGIC1 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie 38 26 2 2 0
ERGIC3_ENST00000348547 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie 53 23 3 3 0
ERLIN1 ERLIN1 O75477 Erlin-1 chr10 Not Cancer Driver No 1 hippie 29 46 4 4 1
ERMP1 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 Not Cancer Driver No 1 hippie 80 93 4 4 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie 66 295 35 35 0
FAM120C FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 162 508 77 77 0
FAM98A FAM98A Q8NCA5 Protein FAM98A chr2 Not Cancer Driver No 1 hippie 63 314 36 36 0
FARS2_ENST00000274680 FARS2 O95363 Phenylalanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie 66 73 17 17 4
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie 291 309 42 42 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FLII FLII Q13045 Protein flightless-1 homolog chr17 Not Cancer Driver No 1 hippie 128 206 32 32 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 intact, hippie 362 1183 170 170 19
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie 43 122 15 15 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie 56 20 3 3 0
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 Not Cancer Driver No 1 hippie 134 96 12 12 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 1 hippie 103 533 66 66 0
FUBP3 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 68 353 51 51 0
FUT4 FUT4 P22083 Alpha-(1,3)-fucosyltransferase 4 chr11 Not Cancer Driver No 1 hippie 49 193 9 9 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GALNT2 GALNT2 Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 Not Cancer Driver No 1 hippie 94 122 22 22 2
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 129 132 20 20 3
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 39 24 3 3 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 Not Cancer Driver No 1 hippie 92 166 27 27 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 hippie 327 117 16 16 0
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie 49 23 2 2 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 Not Cancer Driver No 1 hippie 56 257 21 21 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 hippie 77 73 11 11 24
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 hippie 76 316 28 28 2
GSR GSR P00390 Glutathione reductase, mitochondrial chr8 Not Cancer Driver No 1 hippie 53 55 5 5 1
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 Not Cancer Driver No 1 hippie 32 0 0 0 0
GTF2IRD1_ENST00000265755 GTF2IRD1 Q9UHL9 General transcription factor II-I repeat domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 136 378 56 56 0
GULP1 GULP1 Q9UBP9 PTB domain-containing engulfment adapter protein 1 chr2 Not Cancer Driver No 1 hippie 38 148 19 19 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 Not Cancer Driver No 1 hippie 28 10 0 0 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HELZ2 HELZ2 Q9BYK8 Helicase with zinc finger domain 2 chr20 Not Cancer Driver No 1 hippie 320 594 84 84 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 Not Cancer Driver No 1 hippie 124 118 12 12 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 hippie 68 255 41 41 0
HNRNPA3 HNRNPA3 P51991 Heterogeneous nuclear ribonucleoprotein A3 chr2 Not Cancer Driver No 1 hippie 46 285 37 37 0
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 hippie 65 105 18 18 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie 75 302 59 59 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie 108 463 67 67 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HP1BP3 HP1BP3 Q5SSJ5 Heterochromatin protein 1-binding protein 3 chr1 Not Cancer Driver No 1 hippie 58 404 45 45 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 Not Cancer Driver No 1 hippie 146 364 39 39 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 109 287 36 36 9
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 Not Cancer Driver No 1 hippie 49 52 3 3 0
IFIT2_ENST00000371826 IFIT2 P09913 Interferon-induced protein with tetratricopeptide repeats 2 chr10 Not Cancer Driver No 1 hippie 73 85 17 17 0
IFIT3_ENST00000371811 IFIT3 O14879 Interferon-induced protein with tetratricopeptide repeats 3 chr10 Not Cancer Driver No 1 hippie 47 143 11 11 0
IFIT5 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 Not Cancer Driver No 1 hippie 43 19 0 0 0
IFNA1 IFNA1 L0N195 Interferon-alpha1 chr9 Not Cancer Driver No 2 hippie, biogrid 32 2 1 1 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 Not Cancer Driver No 2 hippie, biogrid 40 1 0 0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 Not Cancer Driver No 1 intact 39 2 0 0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 39 1 1 1 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 38 2 0 0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 Not Cancer Driver No 2 hippie, biogrid 34 0 0 0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 39 1 0 0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 Not Cancer Driver No 3 hippie, biogrid 36 1 0 0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 Not Cancer Driver No 1 hippie, biogrid 43 1 1 1 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 Not Cancer Driver No 3 hippie, biogrid 43 0 0 0 0
IFNL3 IFNL3 Q8IZI9 Interferon lambda-3 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 46 26 5 5 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 32 10 3 3 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie 103 674 82 82 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 hippie 183 351 35 35 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 Not Cancer Driver No 2 intact, hippie 36 204 21 21 1
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 Census, Compendium Yes 1 hippie 147 120 7 7 2
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 Not Cancer Driver No 1 intact, hippie 60 31 6 6 3
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 hippie 74 129 18 18 0
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie 57 165 19 19 0
KRT81 KRT81 Q14533 Keratin, type II cuticular Hb1 chr12 Not Cancer Driver No 1 hippie 52 18 4 4 3
KRT9 KRT9 P35527 Keratin, type I cytoskeletal 9 chr17 Not Cancer Driver No 1 hippie 104 427 68 68 21
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 Not Cancer Driver No 1 hippie 59 99 14 14 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie 47 15 2 2 11
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 Not Cancer Driver No 1 hippie 57 112 19 19 0
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 Not Cancer Driver No 1 hippie 177 880 140 140 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie 63 222 25 25 1
LMAN2 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie 53 36 8 8 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LMO7_ENST00000357063 LMO7 Q8WWI1 LIM domain only protein 7 chr13 Not Cancer Driver No 1 hippie 267 1102 188 188 0
LRRC25_ENST00000595840 LRRC25 Q8N386 Leucine-rich repeat-containing protein 25 chr19 Not Cancer Driver No 1 hippie 40 89 14 14 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie 33 122 15 15 0
LRRFIP2 LRRFIP2 Q9Y608 Leucine-rich repeat flightless-interacting protein 2 chr3 Not Cancer Driver No 1 hippie 75 584 62 62 0
LUZP1_ENST00000418342 LUZP1 Q86V48 Leucine zipper protein 1 chr1 Not Cancer Driver No 1 hippie 102 972 91 91 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 hippie 50 249 31 31 0
MAGT1_ENST00000618282 MAGT1 Q9H0U3 Magnesium transporter protein 1 chrX Not Cancer Driver No 1 hippie 63 0 0 0 1
MAP4 MAP4 P27816 Microtubule-associated protein 4 chr3 Not Cancer Driver No 1 hippie 116 1136 114 114 0
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MDH1_ENST00000233114 MDH1 P40925 Malate dehydrogenase, cytoplasmic chr2 Not Cancer Driver No 1 hippie 41 18 2 2 1
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
MISP MISP Q8IVT2 Mitotic interactor and substrate of PLK1 chr19 Not Cancer Driver No 1 hippie 138 646 132 132 0
MPRIP_ENST00000341712 MPRIP Q6WCQ1 Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 1 hippie 118 735 95 95 0
MRTO4 MRTO4 Q9UKD2 mRNA turnover protein 4 homolog chr1 Not Cancer Driver No 1 hippie 23 73 5 5 0
MSN MSN P26038 Moesin chrX Census, Compendium Yes 1 hippie 108 286 56 56 1
MTDH MTDH Q86UE4 Protein LYRIC chr8 Not Cancer Driver No 1 hippie 83 516 81 81 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 hippie 103 129 11 11 6
MX1_ENST00000398598 MX1 P20591 Interferon-induced GTP-binding protein Mx1 chr21 Not Cancer Driver No 1 hippie 88 74 10 10 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 hippie 144 463 47 47 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 Not Cancer Driver No 1 hippie 258 1134 136 136 0
MYH7B MYH7B A7E2Y1 Myosin-7B chr20 Not Cancer Driver No 1 hippie 294 1103 138 138 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 hippie 310 1120 160 160 17
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 hippie 19 70 13 13 0
MYL12B_ENST00000237500 MYL12B O14950 Myosin regulatory light chain 12B chr18 Not Cancer Driver No 1 hippie 23 61 13 13 0
MYL6B MYL6B P14649 Myosin light chain 6B chr12 Not Cancer Driver No 1 hippie 24 109 14 14 0
MYL6_ENST00000548293 MYL6 P60660 Myosin light polypeptide 6 chr12 Not Cancer Driver No 1 hippie 13 17 1 1 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 1 hippie 144 34 4 4 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 hippie 110 66 11 11 0
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 Not Cancer Driver No 1 hippie 137 229 14 14 1
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 Census, Compendium Yes 1 hippie 224 497 58 58 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 hippie 204 394 43 43 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie 176 342 41 41 3
MYOF MYOF Q9NZM1 Myoferlin chr10 Not Cancer Driver No 1 hippie 269 401 55 55 0
NACA_ENST00000356769 NACA Q13765 Nascent polypeptide-associated complex subunit alpha chr12 Census Yes 1 hippie 37 143 26 26 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 1 hippie 47 207 31 31 0
NARS2 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 79 22 2 2 3
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 1 hippie 109 142 18 18 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie 101 560 51 51 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 hippie 60 305 40 40 6
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 104 344 38 38 0
NUP205 NUP205 Q92621 Nuclear pore complex protein Nup205 chr7 Not Cancer Driver No 1 hippie 251 101 16 16 1
NUP43 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 Not Cancer Driver No 1 hippie 47 103 9 9 0
OGA OGA O60502 Protein O-GlcNAcase chr10 Not Cancer Driver No 1 hippie 89 241 15 15 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie 150 106 19 19 0
OSTC_ENST00000361564 OSTC Q9NRP0 Oligosaccharyltransferase complex subunit OSTC chr4 Not Cancer Driver No 1 hippie 14 0 0 0 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie 100 317 55 55 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 hippie 42 82 11 11 7
PALLD_ENST00000512127 PALLD Q8WX93-8 Isoform 8 of Palladin chr4 Not Cancer Driver No 1 hippie 105 509 65 65 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie 119 320 34 34 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie 65 166 24 24 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 hippie 152 1665 134 134 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie 16 7 1 1 3
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 hippie 73 19 3 3 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie 61 40 5 5 9
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie 16 83 4 4 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie 31 26 4 4 0
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 Not Cancer Driver No 1 hippie 51 38 4 4 8
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 Census Yes 1 hippie 89 320 42 42 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 hippie 677 2130 272 272 2
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie 86 12 0 0 5
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 Not Cancer Driver No 1 hippie 108 65 8 8 1
PLS1 PLS1 Q14651 Plastin-1 chr3 Not Cancer Driver No 1 hippie 100 59 8 8 4
PLS3_ENST00000539310 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie 75 75 5 5 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie 62 93 4 4 9
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie 65 243 31 31 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 hippie 47 25 5 5 5
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 Not Cancer Driver No 1 hippie 114 798 100 100 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 Not Cancer Driver No 1 hippie 107 821 89 89 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie 22 40 5 5 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie 46 13 4 4 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 intact, hippie 538 421 61 61 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRRC2C PRRC2C Q9Y520-4 Isoform 4 of Protein PRRC2C chr1 Not Cancer Driver No 1 hippie 296 2713 287 287 0
PSMA7 PSMA7 O14818 Proteasome subunit alpha type-7 chr20 Not Cancer Driver No 1 hippie 24 23 1 1 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 Not Cancer Driver No 1 hippie 69 152 19 19 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 Not Cancer Driver No 1 hippie 74 154 17 17 0
PYM1 PYM1 Q9BRP8 Partner of Y14 and mago chr12 Not Cancer Driver No 1 hippie 22 204 22 22 0
QSOX2 QSOX2 Q6ZRP7 Sulfhydryl oxidase 2 chr9 Not Cancer Driver No 1 intact, hippie 87 151 16 16 0
QTRT2_ENST00000281273 QTRT2 Q9H974 Queuine tRNA-ribosyltransferase accessory subunit 2 chr3 Not Cancer Driver No 1 hippie 51 30 6 6 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie 31 43 4 4 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RAI14_ENST00000503673 RAI14 Q9P0K7 Ankycorbin chr5 Not Cancer Driver No 1 hippie 117 693 78 78 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie 53 169 23 23 0
RBM15B RBM15B Q8NDT2 Putative RNA-binding protein 15B chr3 Not Cancer Driver No 1 hippie 76 597 48 48 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 hippie 124 549 88 88 0
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 hippie 97 512 66 66 1
RDH11 RDH11 Q8TC12 Retinol dehydrogenase 11 chr14 Not Cancer Driver No 1 hippie 25 2 0 0 0
REEP5 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 1 intact, hippie 34 0 0 0 0
RGS3 RGS3 P49796 Regulator of G-protein signaling 3 chr9 Not Cancer Driver No 1 hippie 157 619 82 82 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 hippie 27 33 2 2 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie 21 70 13 13 0
RPL24 RPL24 P83731 60S ribosomal protein L24 chr3 Not Cancer Driver No 1 hippie 19 105 14 14 0
RPL27A RPL27A P46776 60S ribosomal protein L27a chr11 Not Cancer Driver No 1 hippie 7 56 2 2 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 53 26 4 4 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 hippie 9 52 5 5 2
RPS27A_ENST00000404735 RPS27A P62979 Ubiquitin-40S ribosomal protein S27a chr2 Not Cancer Driver No 1 hippie 18 47 2 2 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 61 275 33 33 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 Not Cancer Driver No 1 hippie 121 866 82 82 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 Not Cancer Driver No 1 hippie 54 67 7 7 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 hippie 62 100 13 13 0
SACM1L SACM1L Q9NTJ5 Phosphatidylinositol-3-phosphatase SAC1 chr3 Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SEC16A SEC16A O15027 Protein transport protein Sec16A chr9 Not Cancer Driver No 1 hippie 285 1923 235 235 0
SEC61A1 SEC61A1 P61619 Protein transport protein Sec61 subunit alpha isoform 1 chr3 Not Cancer Driver No 1 intact, hippie 57 0 0 0 2
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 Not Cancer Driver No 1 hippie 64 355 44 44 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SERPINB5 SERPINB5 P36952 Serpin B5 chr18 Not Cancer Driver No 1 hippie 57 50 7 7 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie 51 52 6 6 1
SF3A2 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie 30 382 21 21 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 1 hippie 154 145 19 19 0
SF3B4 SF3B4 Q15427 Splicing factor 3B subunit 4 chr1 Not Cancer Driver No 1 hippie 69 273 56 56 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 110 440 72 72 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 1 hippie 172 617 73 73 0
SLC1A5 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 Not Cancer Driver No 1 hippie 52 61 7 7 0
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie 49 32 4 4 1
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 hippie 41 0 0 0 0
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie 62 171 12 12 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie 165 406 57 57 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 Not Cancer Driver No 1 hippie 114 80 12 12 1
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie 127 258 48 48 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 Not Cancer Driver No 1 hippie 237 270 37 37 11
SPATS2L_ENST00000409140 SPATS2L Q9NUQ6 SPATS2-like protein chr2 Not Cancer Driver No 1 hippie 69 428 53 53 0
SPATS2_ENST00000552918 SPATS2 Q86XZ4 Spermatogenesis-associated serine-rich protein 2 chr12 Not Cancer Driver No 1 hippie 62 392 52 52 0
SPECC1L SPECC1L Q69YQ0 Cytospin-A chr22 Not Cancer Driver No 1 hippie 113 928 93 93 3
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie 315 980 114 114 0
SQOR_ENST00000568606 SQOR Q9Y6N5 Sulfide:quinone oxidoreductase, mitochondrial chr15 Not Cancer Driver No 1 hippie 54 41 8 8 1
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie 73 329 32 32 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie 41 198 34 34 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie 31 125 27 27 0
SSRP1 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 1 hippie 92 308 35 35 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 1 hippie 131 144 25 25 26
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 Not Cancer Driver No 1 hippie 57 77 6 6 0
STT3B STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 intact, hippie 60 136 9 9 0
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie 147 301 44 44 0
SURF4 SURF4 O15260 Surfeit locus protein 4 chr9 Not Cancer Driver No 1 intact, hippie 29 0 0 0 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 hippie 129 241 34 34 1
TAGLN_ENST00000530649 TAGLN Q01995 Transgelin chr11 Not Cancer Driver No 1 hippie 20 94 12 12 0
TAP1 TAP1 Q03518-2 Isoform 2 of Antigen peptide transporter 1 chr6 Not Cancer Driver No 1 hippie 67 83 6 6 0
TAPBP_ENST00000434618 TAPBP O15533 Tapasin chr6 Not Cancer Driver No 1 hippie 58 168 26 26 0
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 Not Cancer Driver No 1 hippie 68 115 13 13 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie 54 55 10 10 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 intact, hippie 41 0 0 0 1
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie 89 80 6 6 1
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie 137 955 137 137 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TIMM50_ENST00000607714 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 Not Cancer Driver No 1 hippie 39 75 7 7 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie 198 1350 151 151 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 hippie 66 86 7 7 1
TM9SF2 TM9SF2 Q99805 Transmembrane 9 superfamily member 2 chr13 Not Cancer Driver No 1 hippie 82 16 2 2 0
TM9SF3 TM9SF3 Q9HD45 Transmembrane 9 superfamily member 3 chr10 Not Cancer Driver No 1 hippie 57 2 0 0 0
TMEM43 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 Not Cancer Driver No 1 intact, hippie 47 57 9 9 3
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 1 hippie 40 190 24 24 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 137 593 81 81 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 150 508 59 59 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 1 hippie 154 543 46 46 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 1 hippie 33 234 29 29 8
TPM2 TPM2 P07951 Tropomyosin beta chain chr9 Not Cancer Driver No 1 hippie 39 232 35 35 15
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 hippie 35 230 27 27 21
TPM4_ENST00000300933 TPM4 P67936 Tropomyosin alpha-4 chain chr19 Census Yes 1 hippie 28 216 28 28 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 hippie 63 4 1 1 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 Not Cancer Driver No 1 intact 92 257 61 61 0
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 67 53 10 10 12
TUBB6 TUBB6 Q9BUF5 Tubulin beta-6 chain chr18 Not Cancer Driver No 1 hippie 69 51 5 5 1
TXNRD1 TXNRD1 Q16881 Thioredoxin reductase 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie 85 67 9 9 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
UACA UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 Not Cancer Driver No 1 hippie 177 863 101 101 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie 117 165 22 22 6
UBA7 UBA7 P41226 Ubiquitin-like modifier-activating enzyme 7 chr3 Not Cancer Driver No 2 hippie, biogrid 92 166 15 15 0
UBAP2L UBAP2L Q14157 Ubiquitin-associated protein 2-like chr1 Not Cancer Driver No 1 hippie 129 1039 128 128 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 Not Cancer Driver No 1 hippie 21 13 4 4 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 Not Cancer Driver No 1 hippie 21 78 10 10 0
UBE2E2_ENST00000425792 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 Not Cancer Driver No 1 hippie 28 90 15 15 0
UBE2L6 UBE2L6 O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 chr11 Not Cancer Driver No 1 hippie 19 7 1 1 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie 25 24 3 3 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 Not Cancer Driver No 1 hippie 100 567 77 77 1
UGDH_ENST00000506179 UGDH O60701 UDP-glucose 6-dehydrogenase chr4 Not Cancer Driver No 1 hippie 54 39 4 4 5
UGP2 UGP2 Q16851 UTP--glucose-1-phosphate uridylyltransferase chr2 Not Cancer Driver No 1 hippie, biogrid 65 55 7 7 1
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 Not Cancer Driver No 5 intact, hippie 34 29 8 8 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 1 hippie 95 230 47 47 0
UTP4 UTP4 Q969X6 U3 small nucleolar RNA-associated protein 4 homolog chr16 Not Cancer Driver No 1 hippie 63 34 7 7 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie 24 184 14 14 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 Not Cancer Driver No 1 hippie 66 30 7 7 2
WDR33 WDR33 Q9C0J8 pre-mRNA 3' end processing protein WDR33 chr2 Not Cancer Driver No 1 hippie 191 987 153 153 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 hippie 87 118 11 11 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie 41 312 41 41 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 137 597 117 117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 hippie 74 409 51 51 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
ZC3H15 ZC3H15 Q8WU90 Zinc finger CCCH domain-containing protein 15 chr2 Not Cancer Driver No 1 hippie 58 281 44 44 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie 142 344 63 63 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie 67 23 0 0 3
ZNF281_ENST00000367353 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 Not Cancer Driver No 1 hippie 92 709 67 67 0
ZNF318 ZNF318 Q5VUA4 Zinc finger protein 318 chr6 Not Cancer Driver No 1 hippie, biogrid 259 2066 237 237 0