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IRF2BP2 ,IRF2BP2 ,Q7Z5L9
  • Uniprot Accession= Q7Z5L9
  • Ensembl Transcript= ENST00000366609.3
  • Uniprot Name= IRF2BP2
  • Name= Interferon regulatory factor 2-binding protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 21
  • Number of Interaction partner in hippie: 85
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 18 69 2 2 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 hippie, biogrid 29 195 9 9 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX Census, Compendium Yes 1 hippie 291 1285 226 226 1
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
CBFA2T2 CBFA2T2 O43439 Protein CBFA2T2 chr20 Not Cancer Driver No 1 hippie 89 457 58 58 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 Census, Compendium Yes 1 hippie 83 502 70 70 0
CCNL2 CCNL2 Q96S94 Cyclin-L2 chr1 Not Cancer Driver No 3 hippie, biogrid 77 251 33 33 0
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 Not Cancer Driver No 1 hippie 74 501 35 35 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 Not Cancer Driver No 1 hippie, biogrid 65 34 5 5 0
CUTC CUTC Q9NTM9 Copper homeostasis protein cutC homolog chr10 Not Cancer Driver No 1 hippie 43 27 1 1 0
DEK DEK P35659 Protein DEK chr6 Census Yes 1 hippie 47 297 41 41 0
EIF4H EIF4H Q15056 Eukaryotic translation initiation factor 4H chr7 Not Cancer Driver No 1 hippie, biogrid 30 175 17 17 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 Not Cancer Driver No 1 intact, hippie 58 163 16 16 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 intact, hippie 428 323 116 116 2
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FOSL2 FOSL2 P15408 Fos-related antigen 2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 54 323 54 54 0
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 129 132 20 20 3
GCHFR GCHFR P30047 GTP cyclohydrolase 1 feedback regulatory protein chr15 Not Cancer Driver No 2 intact, hippie, biogrid 9 20 0 0 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HMG20A HMG20A Q9NP66 High mobility group protein 20A chr15 Not Cancer Driver No 1 hippie 58 308 44 44 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 5 intact, hippie, biogrid 85 288 73 73 0
IRF2BP1 IRF2BP1 Q8IU81 Interferon regulatory factor 2-binding protein 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 57 354 33 33 0
IRF2BP2 IRF2BP2 Q7Z5L9 Interferon regulatory factor 2-binding protein 2 chr1 Not Cancer Driver No 1 hippie 42 451 26 26 1
IRF2BPL IRF2BPL Q9H1B7 Probable E3 ubiquitin-protein ligase IRF2BPL chr14 Not Cancer Driver No 1 hippie, biogrid 61 526 31 31 1
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 Not Cancer Driver No 1 hippie 68 73 19 19 0
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 Not Cancer Driver No 1 hippie 59 349 46 46 0
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 1 intact, hippie 53 243 38 38 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 Compendium Yes 1 hippie 56 177 29 29 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie, biogrid 35 14 1 1 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 1 intact, hippie 104 8 1 1 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie 352 2347 340 340 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 1 hippie 373 2355 356 356 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 2 hippie, biogrid 194 722 162 162 0
NFIA_ENST00000403491 NFIA Q12857 Nuclear factor 1 A-type chr1 Not Cancer Driver No 1 intact, hippie 78 347 55 55 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 Census Yes 1 intact, hippie 63 254 36 36 3
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 intact, hippie 60 305 40 40 6
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie, biogrid 58 142 23 23 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
RAVER1_ENST00000615032 RAVER1 Q8IY67 Ribonucleoprotein PTB-binding 1 chr19 Not Cancer Driver No 1 intact 61 330 22 22 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM45_ENST00000616198 RBM45 Q8IUH3 RNA-binding protein 45 chr2 Not Cancer Driver No 1 hippie 56 105 20 20 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 hippie, biogrid 196 1064 135 135 2
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 1 hippie 172 617 73 73 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 2 hippie, biogrid 33 164 12 12 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 134 664 82 82 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 intact, hippie 130 744 118 118 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SPEN SPEN Q96T58 Msx2-interacting protein chr1 Census, Compendium Yes 1 hippie 459 3061 393 393 0
SSBP3 SSBP3 Q9BWW4 Single-stranded DNA-binding protein 3 chr1 Not Cancer Driver No 1 hippie 51 321 42 42 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 hippie 54 305 53 53 0
TBXT TBXT O15178 T-box transcription factor T chr6 Not Cancer Driver No 1 intact, hippie 110 253 69 69 1
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 1 hippie 105 680 105 105 3
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 Census Yes 1 hippie 52 649 52 52 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 Not Cancer Driver No 1 hippie 52 157 24 24 1
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 Not Cancer Driver No 1 hippie 55 280 26 26 0
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 intact, hippie 28 223 17 17 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 hippie 554 402 59 59 8
UPRT UPRT Q96BW1 Uracil phosphoribosyltransferase homolog chrX Not Cancer Driver No 3 intact, hippie, biogrid 64 76 15 15 0
VGLL4_ENST00000273038 VGLL4 Q14135 Transcription cofactor vestigial-like protein 4 chr3 Not Cancer Driver No 4 intact, hippie, biogrid 40 276 38 38 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0