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IKBKE ,IKBKE ,Q14164
  • Uniprot Accession= Q14164
  • Ensembl Transcript= ENST00000581977.6
  • Uniprot Name= IKBKE
  • Name= Inhibitor of nuclear factor kappa-B kinase subunit epsilon
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 231
  • Number of Interaction partner in biogrid: 23
  • Number of Interaction partner in hippie: 371
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 120 114 12 12 0
ACOT13 ACOT13 Q9NPJ3 Acyl-coenzyme A thioesterase 13 chr6 Not Cancer Driver No 1 intact, hippie 15 23 2 2 0
ACP1_ENST00000272065 ACP1 P24666 Low molecular weight phosphotyrosine protein phosphatase chr2 Not Cancer Driver No 1 hippie 28 13 2 2 0
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 intact, hippie 73 42 10 10 16
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 Not Cancer Driver No 1 intact 49 48 4 4 0
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 Not Cancer Driver No 1 intact, hippie 31 161 19 19 0
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 23 76 12 12 2
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 Not Cancer Driver No 1 hippie 52 19 1 1 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 intact, hippie 49 20 4 4 0
AP1S1 AP1S1 P61966 AP-1 complex subunit sigma-1A chr7 Not Cancer Driver No 1 hippie 21 0 0 0 0
APPBP2 APPBP2 Q92624 Amyloid protein-binding protein 2 chr17 Not Cancer Driver No 1 hippie 61 10 0 0 0
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 Not Cancer Driver No 1 intact, hippie 16 0 0 0 8
ARMT1 ARMT1 Q9H993 Damage-control phosphatase ARMT1 chr6 Not Cancer Driver No 1 hippie 53 1 0 0 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 Not Cancer Driver No 1 hippie 81 11 0 0 3
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 Census Yes 1 intact, hippie, biogrid 74 25 1 1 1
ATP5PB ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 37 2 0 0 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 intact, hippie 19 9 2 2 0
AZI2 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 Not Cancer Driver No 2 intact, hippie 31 192 13 13 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 17 112 9 9 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie, biogrid 98 861 79 79 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 intact, hippie 37 104 14 14 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 69 83 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 Not Cancer Driver No 1 hippie 44 9 0 0 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
C11orf58 SMAP O00193 Small acidic protein chr11 Not Cancer Driver No 1 intact 22 183 22 22 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie 27 92 10 10 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 42 212 19 19 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 2 intact, hippie 19 115 15 15 7
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 40 41 2 2 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 intact, hippie 33 66 3 3 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 38 73 10 10 0
CBR1 CBR1 P16152 Carbonyl reductase [NADPH] 1 chr21 Not Cancer Driver No 1 hippie 27 62 11 11 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 Not Cancer Driver No 1 intact, hippie 102 528 62 62 0
CCDC58 MIX23 Q4VC31 Protein MIX23 chr3 Not Cancer Driver No 1 intact 17 15 2 2 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 intact, hippie 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact, hippie 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 intact, hippie 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 2 intact, hippie 83 72 10 10 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 intact, hippie 66 5 1 1 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 intact, hippie 41 36 2 2 0
CD209 CD209 Q9NNX6 CD209 antigen chr19 Census Yes 1 hippie 116 42 8 8 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 4 intact, hippie 52 214 31 31 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 intact, hippie 166 83 88 88 36
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 Not Cancer Driver No 1 intact, hippie 3 276 2 2 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 Not Cancer Driver No 1 hippie 74 116 9 9 0
CISD2 CISD2 Q8N5K1 CDGSH iron-sulfur domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie 11 7 0 0 0
CKMT1B_ENST00000441322 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 Not Cancer Driver No 1 hippie 25 77 1 1 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 intact, hippie 32 27 5 5 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 190 71 6 6 1
CNPY2 CNPY2 Q9Y2B0 Protein canopy homolog 2 chr12 Not Cancer Driver No 1 hippie 24 24 3 3 0
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 Not Cancer Driver No 1 hippie 59 59 9 9 0
CORO1B CORO1B Q9BR76 Coronin-1B chr11 Not Cancer Driver No 1 intact, hippie 41 138 10 10 0
COTL1 COTL1 Q14019 Coactosin-like protein chr16 Not Cancer Driver No 1 intact, hippie 17 7 2 2 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 17 5 1 1 1
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 1 intact, hippie 85 484 75 75 0
CRYZ_ENST00000340866 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie 49 0 0 0 0
CSTF3 CSTF3 Q12996 Cleavage stimulation factor subunit 3 chr11 Not Cancer Driver No 1 intact, hippie 82 122 15 15 0
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 Not Cancer Driver No 1 intact, hippie 70 83 10 10 0
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 intact, hippie 12 19 3 3 1
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 Not Cancer Driver No 1 hippie 7 0 0 0 0
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 hippie 46 253 32 32 0
DDT_ENST00000350608 DDT P30046 D-dopachrome decarboxylase chr22 Not Cancer Driver No 1 hippie 4 0 0 0 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 intact, hippie 72 342 30 30 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 2 intact, hippie 133 301 47 47 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie 53 190 32 32 1
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 intact, hippie 35 196 26 26 0
DSP DSP P15924 Desmoplakin chr6 Not Cancer Driver No 1 intact, hippie 483 1124 204 204 6
DSTN DSTN P60981 Destrin chr20 Not Cancer Driver No 1 hippie 18 0 0 0 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 Not Cancer Driver No 1 hippie, biogrid 112 112 4 4 2
ECHS1 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 1 hippie 51 7 1 1 14
EEF1B2_ENST00000236957 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie 63 71 11 11 0
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 Not Cancer Driver No 1 intact, hippie 40 153 22 22 0
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX Not Cancer Driver No 1 hippie 52 51 7 7 1
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 Not Cancer Driver No 1 intact, hippie 181 835 130 130 0
EIF3D EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 1 intact, hippie 63 200 26 26 0
EIF3M EIF3M Q7L2H7 Eukaryotic translation initiation factor 3 subunit M chr11 Not Cancer Driver No 1 intact, hippie 44 0 0 0 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie 94 589 90 90 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 1 hippie 229 1079 153 153 2
EIF4H EIF4H Q15056 Eukaryotic translation initiation factor 4H chr7 Not Cancer Driver No 1 hippie 30 175 17 17 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 Not Cancer Driver No 1 intact, hippie 64 185 23 23 0
EMC3 EMC3 Q9P0I2 ER membrane protein complex subunit 3 chr3 Not Cancer Driver No 1 intact, hippie 26 31 6 6 0
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 Not Cancer Driver No 1 intact 204 372 62 62 1
ERG28 ERG28 Q9UKR5 Ergosterol biosynthetic protein 28 homolog chr14 Not Cancer Driver No 1 intact, hippie 19 3 0 0 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 intact, hippie 29 34 5 5 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ETF1 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 intact, hippie 60 28 11 11 0
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 30 34 2 2 3
ETFB_ENST00000309244 ETFB P38117 Electron transfer flavoprotein subunit beta chr19 Not Cancer Driver No 1 intact, hippie 37 38 4 4 2
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 Not Cancer Driver No 1 hippie 15 4 4 4 0
FAM162A FAM162A Q96A26 Protein FAM162A chr3 Not Cancer Driver No 1 hippie 18 53 8 8 0
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 Not Cancer Driver No 1 intact 53 78 11 11 0
FH FH P07954 Fumarate hydratase, mitochondrial chr1 Census, Compendium Yes 1 intact, hippie 67 76 5 5 13
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX Not Cancer Driver No 1 intact, hippie 56 51 7 7 13
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 intact, hippie 70 150 20 20 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 85 352 65 65 0
GARS GARS1 P41250 Glycine--tRNA ligase chr7 Not Cancer Driver No 1 intact 61 75 9 9 17
GLO1 GLO1 Q04760 Lactoylglutathione lyase chr6 Not Cancer Driver No 1 hippie 24 46 7 7 0
GLOD4_ENST00000301328 GLOD4 Q9HC38 Glyoxalase domain-containing protein 4 chr17 Not Cancer Driver No 1 intact, hippie 34 44 3 3 0
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 intact, hippie 52 24 4 4 0
GMFB GMFB P60983 Glia maturation factor beta chr14 Not Cancer Driver No 1 intact, hippie 18 11 0 0 0
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 Census, Compendium Yes 1 hippie 88 76 10 10 0
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 intact, hippie 50 21 0 0 7
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRWD1 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 44 187 14 14 0
GSPT1_ENST00000563468 GSPT1 P15170 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A chr16 Not Cancer Driver No 1 hippie 42 149 13 13 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 72 19 2 2 5
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 intact, hippie 46 145 14 14 0
HMGCS1_ENST00000433297 HMGCS1 Q01581 Hydroxymethylglutaryl-CoA synthase, cytoplasmic chr5 Not Cancer Driver No 1 hippie 64 74 10 10 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 intact, hippie 42 227 35 35 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 intact, hippie 51 169 29 29 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 intact, hippie 108 463 67 67 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX Not Cancer Driver No 1 intact, hippie 22 3 0 0 62
HSDL2 HSDL2 Q6YN16 Hydroxysteroid dehydrogenase-like protein 2 chr9 Not Cancer Driver No 1 intact, hippie 37 41 5 5 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact, hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 67 283 26 26 2
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 8 3 0 0 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 132 373 47 47 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 109 287 36 36 9
IFIT3_ENST00000371811 IFIT3 O14879 Interferon-induced protein with tetratricopeptide repeats 3 chr10 Not Cancer Driver No 1 hippie 47 143 11 11 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 Not Cancer Driver No 1 hippie 141 298 80 80 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 hippie 106 211 31 31 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 6 301 6 6 22
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 70 6 1 1 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 Not Cancer Driver No 2 intact, hippie 36 204 21 21 1
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 Not Cancer Driver No 1 hippie 93 237 64 64 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 Not Cancer Driver No 1 intact, hippie 43 253 19 19 1
ISYNA1 ISYNA1 Q9NPH2 Inositol-3-phosphate synthase 1 chr19 Not Cancer Driver No 1 hippie 40 83 2 2 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 Not Cancer Driver No 1 intact 88 160 15 15 12
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 90 389 26 26 4
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 intact, hippie 122 586 67 67 0
KTN1 KTN1 Q86UP2 Kinectin chr14 Census Yes 1 intact, hippie 138 964 102 102 0
LAGE3 LAGE3 Q14657 EKC/KEOPS complex subunit LAGE3 chrX Not Cancer Driver No 1 hippie 16 95 8 8 2
LCP1 LCP1 P13796 Plastin-2 chr13 Census Yes 1 hippie, biogrid 99 73 11 11 0
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 intact, hippie 62 9 0 0 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LRRC10B LRRC10B A6NIK2 Leucine-rich repeat-containing protein 10B chr11 Not Cancer Driver No 1 hippie 1 94 1 1 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 intact, hippie 33 122 15 15 0
LSM12 LSM12 Q3MHD2 Protein LSM12 homolog chr17 Not Cancer Driver No 1 intact, hippie 13 66 7 7 0
LTA4H LTA4H P09960 Leukotriene A-4 hydrolase chr12 Not Cancer Driver No 1 hippie 59 39 6 6 0
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie 19 12 2 2 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 intact, hippie 26 12 1 1 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 Census Yes 1 intact, hippie 35 301 34 34 10
MANF MANF P55145 Mesencephalic astrocyte-derived neurotrophic factor chr3 Not Cancer Driver No 1 hippie 14 1 0 0 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie 26 109 11 11 0
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 Not Cancer Driver No 1 hippie 36 31 4 4 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 70 411 58 58 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 Not Cancer Driver No 1 hippie 52 304 52 52 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 intact, hippie 104 275 38 38 1
MIF MIF P14174 Macrophage migration inhibitory factor chr22 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
MLEC MLEC Q14165 Malectin chr12 Not Cancer Driver No 1 intact, hippie 42 51 6 6 0
MRPL12 MRPL12 P52815 39S ribosomal protein L12, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 21 22 6 6 1
MRPL14 MRPL14 Q6P1L8 39S ribosomal protein L14, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 21 36 6 6 0
MRPS14 MRPS14 O60783 28S ribosomal protein S14, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 26 4 1 1 1
MSN MSN P26038 Moesin chrX Census, Compendium Yes 1 hippie 108 286 56 56 1
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie, biogrid 117 139 11 11 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie 11 11 3 3 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 Census, Compendium Yes 1 hippie 37 47 1 1 2
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 258 1134 136 136 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 2 intact, hippie 19 70 13 13 0
MYL6_ENST00000548293 MYL6 P60660 Myosin light polypeptide 6 chr12 Not Cancer Driver No 2 intact, hippie 13 17 1 1 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 intact, hippie 176 342 41 41 3
MZT2B_ENST00000281871 MZT2B Q6NZ67 Mitotic-spindle organizing protein 2B chr2 Not Cancer Driver No 1 intact, hippie 14 113 14 14 0
NAA10 NAA10 P41227 N-alpha-acetyltransferase 10 chrX Not Cancer Driver No 1 hippie 33 117 17 17 3
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 Not Cancer Driver No 1 intact, hippie 95 115 17 17 0
NAA20 NAA20 P61599 N-alpha-acetyltransferase 20 chr20 Not Cancer Driver No 1 hippie 26 28 6 6 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 1 intact, hippie 47 207 31 31 0
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 Not Cancer Driver No 1 hippie 33 11 0 0 0
NARS NARS1 O43776 Asparagine--tRNA ligase, cytoplasmic chr18 Not Cancer Driver No 1 intact 50 103 16 16 4
NASP NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 1 intact, hippie 95 615 81 81 0
NCBP2_ENST00000427641 NCBP2 P52298-3 Isoform 3 of Nuclear cap-binding protein subunit 2 chr3 Not Cancer Driver No 1 hippie 21 61 9 9 0
NCDN_ENST00000356090 NCDN Q9UBB6 Neurochondrin chr1 Not Cancer Driver No 1 hippie 77 21 5 5 3
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 hippie 37 102 9 9 1
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact, hippie 29 249 22 22 0
NTMT1_ENST00000613644 NTMT1 Q9BV86 N-terminal Xaa-Pro-Lys N-methyltransferase 1 chr9 Not Cancer Driver No 1 hippie 27 1 0 0 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 intact, hippie 21 37 3 3 0
NUDT5_ENST00000537776 NUDT5 Q9UKK9 ADP-sugar pyrophosphatase chr10 Not Cancer Driver No 1 hippie 27 90 11 11 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 intact, hippie 45 128 18 18 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 intact, hippie, biogrid 100 317 55 55 0
PABPC4_ENST00000372857 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 intact, hippie 89 253 49 49 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 intact, hippie 57 299 30 30 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 intact, hippie 119 320 34 34 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 intact, hippie 65 166 24 24 0
PCMT1_ENST00000464889 PCMT1 A0A0A0MRJ6 Protein-L-isoaspartate O-methyltransferase chr6 Not Cancer Driver No 1 intact, hippie 34 38 4 4 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 Not Cancer Driver No 1 hippie 15 91 7 7 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 intact, hippie 85 272 22 22 0
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 32 4 0 0 2
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie 81 147 22 22 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 55 82 11 11 0
PDXK PDXK O00764 Pyridoxal kinase chr21 Not Cancer Driver No 1 hippie 27 47 6 6 2
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 Not Cancer Driver No 1 hippie 157 380 36 36 0
PFDN1 PFDN1 O60925 Prefoldin subunit 1 chr5 Not Cancer Driver No 1 intact, hippie 8 42 4 4 0
PFDN2 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie 18 111 11 11 0
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 1 hippie 18 3 0 0 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 Not Cancer Driver No 1 intact, hippie 91 29 4 4 0
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 intact, hippie 73 19 3 3 0
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 30 74 16 16 0
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie 16 83 4 4 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie 31 26 4 4 0
PITPNB_ENST00000335272 PITPNB P48739 Phosphatidylinositol transfer protein beta isoform chr22 Not Cancer Driver No 1 intact, hippie 26 69 2 2 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLP2 PLP2 Q04941 Proteolipid protein 2 chrX Not Cancer Driver No 1 hippie 40 10 3 3 0
PLS3_ENST00000539310 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie, biogrid 75 75 5 5 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 Not Cancer Driver No 1 hippie 38 29 2 2 5
POLR2H_ENST00000456318 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 1 intact, hippie 16 14 1 1 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 intact, hippie 28 16 1 1 1
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 1 intact, hippie 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 intact, hippie, biogrid 179 0 0 0 4
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 Not Cancer Driver No 1 hippie 41 0 0 0 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 Not Cancer Driver No 1 hippie 22 0 0 0 0
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie 68 320 41 41 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 intact, hippie 71 109 16 16 0
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 intact, hippie 48 51 9 9 0
PSMA2 PSMA2 P25787 Proteasome subunit alpha type-2 chr7 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
PSMA6 PSMA6 P60900 Proteasome subunit alpha type-6 chr14 Not Cancer Driver No 1 intact, hippie 37 2 1 1 0
PSMA7 PSMA7 O14818 Proteasome subunit alpha type-7 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 24 23 1 1 0
PSMB1 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 intact, hippie 25 14 2 2 0
PSMB4 PSMB4 P28070 Proteasome subunit beta type-4 chr1 Not Cancer Driver No 1 intact, hippie 23 18 2 2 0
PSMB6 PSMB6 P28072 Proteasome subunit beta type-6 chr17 Not Cancer Driver No 1 intact, hippie 19 22 1 1 0
PSMC2_ENST00000292644 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 Not Cancer Driver No 1 intact, hippie 63 120 13 13 0
PSMC4 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 1 hippie 51 21 3 3 0
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 Not Cancer Driver No 1 intact, hippie 49 69 8 8 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 intact, hippie 110 201 19 19 0
PSMD12 PSMD12 O00232 26S proteasome non-ATPase regulatory subunit 12 chr17 Not Cancer Driver No 1 intact, hippie 48 24 3 3 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 intact, hippie 100 135 14 14 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 69 152 19 19 0
PSMD6_ENST00000295901 PSMD6 Q15008 26S proteasome non-ATPase regulatory subunit 6 chr3 Not Cancer Driver No 1 intact, hippie 33 40 3 3 0
PSMD7 PSMD7 P51665 26S proteasome non-ATPase regulatory subunit 7 chr16 Not Cancer Driver No 1 intact, hippie 39 70 4 4 0
PSME2 PSME2 Q9UL46 Proteasome activator complex subunit 2 chr14 Not Cancer Driver No 1 hippie 32 39 3 3 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 20 25 5 5 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie 11 52 3 3 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 14 19 2 2 1
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 Not Cancer Driver No 1 intact 101 106 16 16 4
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie 31 43 4 4 0
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 intact, hippie 20 41 4 4 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 Not Cancer Driver No 1 intact, hippie 23 59 4 4 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie 24 50 4 4 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 intact, hippie 27 11 0 0 4
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 1 intact, hippie 19 137 16 16 0
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 72 41 3 3 2
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 intact, hippie 67 138 19 19 0
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 Not Cancer Driver No 1 hippie 35 135 32 32 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 Not Cancer Driver No 1 intact, hippie 71 297 37 37 1
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 hippie 82 277 39 39 4
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 145 732 81 81 0
RPL18A RPL18A Q02543 60S ribosomal protein L18a chr19 Not Cancer Driver No 1 intact, hippie 28 25 4 4 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 Census, Compendium Yes 1 intact, hippie 26 15 1 1 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 intact, hippie 21 70 13 13 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 intact, hippie 34 79 3 3 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 intact, hippie 19 69 14 14 0
RPL32_ENST00000435983 RPL32 P62910 60S ribosomal protein L32 chr3 Not Cancer Driver No 1 intact, hippie 11 75 5 5 0
RPL36_ENST00000347512 RPL36 Q9Y3U8 60S ribosomal protein L36 chr19 Not Cancer Driver No 1 intact, hippie 7 66 4 4 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 intact, hippie 50 69 3 3 0
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 intact, hippie 18 6 0 0 0
RPS14_ENST00000521466 RPS14 P62263 40S ribosomal protein S14 chr5 Not Cancer Driver No 1 intact, hippie 14 96 13 13 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 1 intact, hippie 16 14 1 1 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 intact, hippie 15 61 3 3 23
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 intact, hippie 21 85 5 5 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 intact, hippie 23 34 5 5 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 Not Cancer Driver No 1 hippie 74 41 7 7 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 Not Cancer Driver No 2 intact, hippie 54 67 7 7 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 62 100 13 13 0
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 Not Cancer Driver No 1 hippie 39 90 6 6 0
SAR1A_ENST00000373238 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 Not Cancer Driver No 1 intact, hippie 23 4 0 0 0
SBDS SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 Census Yes 1 hippie 28 12 1 1 2
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 intact, hippie 115 71 13 13 7
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 1 intact, hippie 37 17 3 3 23
SEC23B SEC23B Q15437 Protein transport protein Sec23B chr20 Not Cancer Driver No 1 hippie 105 82 4 4 7
SEPT2_ENST00000360051 SEPTIN2 Q15019 Septin-2 chr2 Not Cancer Driver No 1 intact 49 101 11 11 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 35 221 26 26 2
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie 82 631 67 67 0
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie 244 477 80 80 0
SF3B6 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 intact, hippie 9 10 0 0 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 Not Cancer Driver No 1 intact, hippie 38 159 23 23 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 57 58 5 5 1
SIKE1_ENST00000060969 SIKE1 Q9BRV8 Suppressor of IKBKE 1 chr1 Not Cancer Driver No 1 hippie 23 107 9 9 0
SLK SLK Q9H2G2 STE20-like serine/threonine-protein kinase chr10 Not Cancer Driver No 1 hippie 134 962 96 96 0
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 intact, hippie 349 1072 195 195 5
SMARCC1 SMARCC1 Q92922 SWI/SNF complex subunit SMARCC1 chr3 Not Cancer Driver No 1 intact, hippie 125 720 81 81 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 intact, hippie 175 539 55 55 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie, biogrid 127 258 48 48 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 Not Cancer Driver No 1 intact, hippie 237 270 37 37 11
SNRPA1 SNRPA1 P09661 U2 small nuclear ribonucleoprotein A' chr15 Not Cancer Driver No 1 intact, hippie 33 93 14 14 0
SNRPB2_ENST00000377943 SNRPB2 P08579 U2 small nuclear ribonucleoprotein B'' chr20 Not Cancer Driver No 1 intact, hippie 18 100 7 7 0
SNX3 SNX3 O60493 Sorting nexin-3 chr6 Not Cancer Driver No 1 hippie 21 37 4 4 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 32 25 5 5 0
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 intact, hippie 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 intact, hippie 311 869 123 123 0
SRM SRM P19623 Spermidine synthase chr1 Not Cancer Driver No 1 intact, hippie 27 23 0 0 0
SRP14 SRP14 P37108 Signal recognition particle 14 kDa protein chr15 Not Cancer Driver No 1 intact, hippie 10 74 8 8 0
SSB SSB P05455 Lupus La protein chr2 Not Cancer Driver No 1 intact, hippie 39 181 18 18 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie 26 114 10 10 0
ST13 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 intact, hippie 38 297 29 29 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
STK16_ENST00000396738 STK16 O75716 Serine/threonine-protein kinase 16 chr2 Not Cancer Driver No 1 intact, hippie 42 48 3 3 0
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 1 hippie 44 40 5 5 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 intact, hippie 28 83 12 12 0
TALDO1 TALDO1 P37837 Transaldolase chr11 Not Cancer Driver No 1 intact, hippie 51 31 4 4 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 6 intact, hippie, biogrid 42 302 26 26 0
TARS_ENST00000265112 TARS1 P26639 Threonine--tRNA ligase 1, cytoplasmic chr5 Not Cancer Driver No 1 intact 112 112 22 22 2
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TBCA_ENST00000380377 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie 8 30 1 1 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 intact, hippie 101 42 5 5 12
TBKBP1 TBKBP1 A7MCY6 TANK-binding kinase 1-binding protein 1 chr17 Not Cancer Driver No 3 intact, hippie 52 404 31 31 0
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 Not Cancer Driver No 1 hippie 88 413 56 56 5
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie 54 55 10 10 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie 25 110 15 15 1
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 intact, hippie 89 80 6 6 1
THOP1 THOP1 P52888 Thimet oligopeptidase chr19 Not Cancer Driver No 1 hippie 90 91 12 12 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 Not Cancer Driver No 1 hippie 92 443 66 66 1
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 intact, hippie 66 86 7 7 1
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 intact, hippie 16 22 2 2 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 Not Cancer Driver No 1 intact 46 66 13 13 3
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 Not Cancer Driver No 1 hippie 24 6 0 0 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 Census, Compendium Yes 1 hippie 98 231 33 33 1
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 hippie 58 111 15 15 12
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 1 hippie 85 625 83 83 0
TOMM34 TOMM34 Q15785 Mitochondrial import receptor subunit TOM34 chr20 Not Cancer Driver No 1 hippie 32 113 15 15 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 Not Cancer Driver No 1 hippie 149 795 105 105 0
TPD52L2_ENST00000346249 TPD52L2 O43399 Tumor protein D54 chr20 Not Cancer Driver No 1 hippie 25 180 22 22 0
TPD52_ENST00000379097 TPD52 P55327 Tumor protein D52 chr8 Not Cancer Driver No 1 hippie 25 177 19 19 0
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 2 intact, hippie 35 230 27 27 21
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 intact, hippie 17 43 6 6 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 63 4 1 1 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 Not Cancer Driver No 1 hippie 59 410 39 39 2
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 2 intact, hippie 61 101 9 9 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 59 87 11 11 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 intact, hippie 87 430 41 41 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 Not Cancer Driver No 1 hippie 86 47 15 15 0
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 Not Cancer Driver No 1 hippie 15 17 2 2 0
TSN TSN Q15631 Translin chr2 Not Cancer Driver No 1 intact, hippie 30 0 0 0 0
TSNAX TSNAX Q99598 Translin-associated protein X chr1 Not Cancer Driver No 1 hippie 23 68 3 3 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 Not Cancer Driver No 1 intact, hippie 69 100 6 6 0
TUBA3C TUBA3C P0DPH7 Tubulin alpha-3C chain chr13 Not Cancer Driver No 1 intact 185 36 14 14 0
TUBA3D TUBA3D P0DPH8 Tubulin alpha-3D chain chr2 Not Cancer Driver No 1 hippie 74 36 4 4 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 40 63 11 11 5
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 intact, hippie 91 61 16 16 2
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie 50 52 3 3 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie 84 219 33 33 0
UBC UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 1 intact 97 312 53 53 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 intact, hippie 16 16 3 3 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 Not Cancer Driver No 1 hippie 24 33 3 3 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 intact, hippie 30 32 6 6 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie 25 24 3 3 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie 33 34 7 7 4
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 intact, hippie 169 161 20 20 0
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 Not Cancer Driver No 1 intact, hippie 10 41 1 1 0
VAMP1 VAMP1 P23763 Vesicle-associated membrane protein 1 chr12 Not Cancer Driver No 1 intact, hippie 8 56 4 4 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie 11 17 1 1 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 intact, hippie, biogrid 88 186 16 16 16
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie 38 36 4 4 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
VMA21 VMA21 Q3ZAQ7 Vacuolar ATPase assembly integral membrane protein VMA21 chrX Not Cancer Driver No 1 intact, hippie 18 7 1 1 0
WDR82 WDR82 Q6UXN9 WD repeat-containing protein 82 chr3 Not Cancer Driver No 1 hippie 35 0 0 0 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 89 55 6 6 0
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie 112 64 7 7 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 Not Cancer Driver No 1 intact 62 109 9 9 3
YPEL5 YPEL5 P62699 Protein yippee-like 5 chr2 Not Cancer Driver No 1 hippie 19 10 3 3 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 Not Cancer Driver No 1 intact 97 385 80 80 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 Not Cancer Driver No 1 hippie 90 396 44 44 0
ZC3H15 ZC3H15 Q8WU90 Zinc finger CCCH domain-containing protein 15 chr2 Not Cancer Driver No 1 intact, hippie 58 281 44 44 0