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HIST2H2BE ,H2BC21 ,Q16778
  • Uniprot Accession= Q16778
  • Ensembl Transcript= ENST00000369155.3
  • Uniprot Name= H2BC21
  • Name= Histone H2B type 2-E
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 138
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 0
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 Not Cancer Driver No 1 intact 227 131 29 29 9
ADHFE1 ADHFE1 Q8IWW8 Hydroxyacid-oxoacid transhydrogenase, mitochondrial chr8 Not Cancer Driver No 1 intact 63 37 8 8 0
ARHGAP30 ARHGAP30 Q7Z6I6 Rho GTPase-activating protein 30 chr1 Not Cancer Driver No 1 intact 199 854 151 151 0
ATAD1_ENST00000328142 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 Not Cancer Driver No 1 intact 32 71 3 3 0
ATP2B3_ENST00000349466 ATP2B3 Q16720 Plasma membrane calcium-transporting ATPase 3 chrX Census Yes 1 intact 245 328 74 74 2
ATXN7L1 ATXN7L1 Q9ULK2 Ataxin-7-like protein 1 chr7 Not Cancer Driver No 1 intact 60 710 48 48 0
BAHCC1 BAHCC1 Q9P281 BAH and coiled-coil domain-containing protein 1 chr17 Not Cancer Driver No 1 intact 180 2253 142 142 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 intact 115 546 73 73 10
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 1 intact 34 149 10 10 0
C2CD3 C2CD3 Q4AC94 C2 domain-containing protein 3 chr11 Not Cancer Driver No 1 intact 249 1104 106 106 1
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 Not Cancer Driver No 1 intact 40 0 0 0 0
C8orf33 C8orf33 Q9H7E9 UPF0488 protein C8orf33 chr8 Not Cancer Driver No 1 intact 34 172 26 26 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 Not Cancer Driver No 1 intact 74 75 16 16 4
CC2D1B CC2D1B Q5T0F9 Coiled-coil and C2 domain-containing protein 1B chr1 Not Cancer Driver No 1 intact 94 618 71 71 0
CCDC113 CCDC113 Q9H0I3 Coiled-coil domain-containing protein 113 chr16 Not Cancer Driver No 1 intact 44 118 22 22 0
CEP78_ENST00000424347 CEP78 Q5JTW2 Centrosomal protein of 78 kDa chr9 Not Cancer Driver No 1 intact 79 295 32 32 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 Not Cancer Driver No 1 intact 105 88 7 7 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 Not Cancer Driver No 1 intact 76 91 5 5 0
CRYBG1 CRYBG1 Q9Y4K1 Beta/gamma crystallin domain-containing protein 1 chr6 Not Cancer Driver No 1 intact 211 1006 124 124 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact 151 65 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact 123 167 23 23 3
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 intact 138 207 38 38 2
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact 97 5 1 1 0
DDX60L DDX60L Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like chr4 Not Cancer Driver No 1 intact 219 84 10 10 0
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 intact 110 180 30 30 0
DNAAF2 DNAAF2 Q9NVR5 Protein kintoun chr14 Not Cancer Driver No 1 intact 77 579 37 37 0
DNAH2_ENST00000389173 DNAH2 Q9P225 Dynein axonemal heavy chain 2 chr17 Not Cancer Driver No 1 intact 663 246 42 42 1
DNAH5 DNAH5 Q8TE73 Dynein axonemal heavy chain 5 chr5 Not Cancer Driver No 1 intact 1431 296 111 111 12
DNAJC13 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 intact 276 141 17 17 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 Not Cancer Driver No 1 intact 43 15 4 4 0
EME1_ENST00000338165 EME1 Q96AY2 Crossover junction endonuclease EME1 chr17 Not Cancer Driver No 1 intact 56 296 30 30 0
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 Not Cancer Driver No 1 intact 204 372 62 62 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact 121 195 27 27 2
FMNL2 FMNL2 Q96PY5 Formin-like protein 2 chr2 Not Cancer Driver No 1 intact 119 409 56 56 0
FSCN1 FSCN1 Q16658 Fascin chr7 Not Cancer Driver No 1 intact 58 81 5 5 0
FYB1_ENST00000515010 FYB1 O15117 FYN-binding protein 1 chr5 Not Cancer Driver No 1 intact 176 687 161 161 0
GOLGA6L2 GOLGA6L2 Q8N9W4 Golgin subfamily A member 6-like protein 2 chr15 Not Cancer Driver No 1 intact 57 830 50 50 0
GPR50 GPR50 Q13585 Melatonin-related receptor chrX Not Cancer Driver No 1 intact 170 285 100 100 0
GTPBP10 GTPBP10 A4D1E9 GTP-binding protein 10 chr7 Not Cancer Driver No 1 intact 50 52 4 4 0
H1F0 H1-0 P07305 Histone H1.0 chr22 Not Cancer Driver No 1 intact 16 194 16 16 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 1 intact 20 68 10 10 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 Not Cancer Driver No 1 intact 23 71 16 16 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 37 210 35 35 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 66 224 66 66 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 Not Cancer Driver No 1 intact 66 213 63 63 0
HIST1H1T H1-6 P22492 Histone H1t chr6 Not Cancer Driver No 1 intact 49 158 38 38 0
HIST1H2AJ H2AC14 Q99878 Histone H2A type 1-J chr6 Not Cancer Driver No 1 intact 28 56 11 11 0
HIST1H2BM H2BC14 Q99879 Histone H2B type 1-M chr6 Not Cancer Driver No 1 intact 37 75 23 23 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST2H3C H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 1 51 0 0 0
HIST2H3D H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 29 51 11 11 0
HIST3H3 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 37 51 10 10 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
HMGN2 HMGN2 P05204 Non-histone chromosomal protein HMG-17 chr1 Not Cancer Driver No 1 intact 10 90 10 10 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 intact 75 302 59 59 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact 77 504 45 45 0
IFT74_ENST00000433700 IFT74 Q96LB3 Intraflagellar transport protein 74 homolog chr9 Not Cancer Driver No 1 intact 47 490 38 38 0
IGSF3_ENST00000369486 IGSF3 O75054 Immunoglobulin superfamily member 3 chr1 Not Cancer Driver No 1 intact 184 224 34 34 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 Not Cancer Driver No 1 intact 107 856 103 103 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 intact 85 288 73 73 0
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 Not Cancer Driver No 1 intact 78 215 33 33 0
KIAA1549L KIAA1549L Q6ZVL6 UPF0606 protein KIAA1549L chr11 Not Cancer Driver No 1 intact 321 1304 225 225 0
KLHL7 KLHL7 Q8IXQ5 Kelch-like protein 7 chr7 Not Cancer Driver No 1 intact 85 31 4 4 6
LENG8 LENG8 Q96PV6 Leukocyte receptor cluster member 8 chr19 Not Cancer Driver No 1 intact 137 515 97 97 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 intact 68 544 49 49 131
LMNTD1_ENST00000282881 LMNTD1 Q8N9Z9 Lamin tail domain-containing protein 1 chr12 Not Cancer Driver No 1 intact 71 129 24 24 0
LRRFIP2 LRRFIP2 Q9Y608 Leucine-rich repeat flightless-interacting protein 2 chr3 Not Cancer Driver No 1 intact 75 584 62 62 0
LYG2 LYG2 Q86SG7 Lysozyme g-like protein 2 chr2 Not Cancer Driver No 1 intact 38 1 1 1 0
MAGEA8_ENST00000542674 MAGEA8 P43361 Melanoma-associated antigen 8 chrX Not Cancer Driver No 1 intact 65 112 19 19 0
MAGIX MAGIX Q9H6Y5 PDZ domain-containing protein MAGIX chrX Not Cancer Driver No 1 intact 51 285 50 50 0
MAP3K9_ENST00000554752 MAP3K9 P80192 Mitogen-activated protein kinase kinase kinase 9 chr14 Not Cancer Driver No 1 intact 167 684 104 104 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 intact 143 649 55 55 0
MESD_ENST00000561312 MESD Q14696 LRP chaperone MESD chr15 Not Cancer Driver No 1 intact 21 150 14 14 0
MICAL1_ENST00000358807 MICAL1 Q8TDZ2 [F-actin]-monooxygenase MICAL1 chr6 Not Cancer Driver No 1 intact 112 364 37 37 0
MICA_ENST00000616296 MICA A0A024RCL3 MHC class I polypeptide-related sequence A chr6 Not Cancer Driver No 1 intact 37 49 8 8 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 Not Cancer Driver No 1 intact 124 1041 116 116 0
MVP MVP Q14764 Major vault protein chr16 Not Cancer Driver No 1 intact 141 285 31 31 0
NEB_ENST00000172853 NEB P20929 Nebulin chr2 Not Cancer Driver No 1 intact 1188 1984 355 355 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 intact 116 510 72 72 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact 29 249 22 22 0
NSD1 NSD1 Q96L73 Histone-lysine N-methyltransferase, H3 lysine-36 specific chr5 Census, Compendium Yes 1 intact 343 1864 206 206 14
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 intact 58 333 40 40 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 Not Cancer Driver No 1 intact 1208 2623 368 368 0
OSBPL6_ENST00000190611 OSBPL6 Q9BZF3 Oxysterol-binding protein-related protein 6 chr2 Not Cancer Driver No 1 intact 167 365 72 72 0
P3H1_ENST00000296388 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 Not Cancer Driver No 1 intact 91 177 18 18 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 Not Cancer Driver No 1 intact 57 187 32 32 0
PHF2 PHF2 O75151 Lysine-specific demethylase PHF2 chr9 Not Cancer Driver No 1 intact 131 725 80 80 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 intact 154 603 93 93 1
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 Not Cancer Driver No 1 intact 256 365 60 60 0
PWWP2A PWWP2A Q96N64 PWWP domain-containing protein 2A chr5 Census Yes 1 intact 57 601 46 46 0
REST REST Q13127 RE1-silencing transcription factor chr4 Not Cancer Driver No 1 intact 142 868 113 113 4
RGS6_ENST00000553530 RGS6 P49758 Regulator of G-protein signaling 6 chr14 Not Cancer Driver No 1 intact 118 61 21 21 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 Not Cancer Driver No 1 intact 145 732 81 81 0
RPL19 RPL19 P84098 60S ribosomal protein L19 chr17 Not Cancer Driver No 1 intact 30 121 21 21 0
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 Not Cancer Driver No 1 intact 83 568 67 67 0
SEPT1 SEPTIN1 J3KNL2 Septin chr16 Not Cancer Driver No 1 intact 44 102 10 10 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 Census Yes 1 intact 81 68 22 22 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 1 intact 31 131 17 17 0
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 Not Cancer Driver No 1 intact 164 1025 134 134 0
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 intact 75 436 63 63 0
SMC1B SMC1B Q8NDV3 Structural maintenance of chromosomes protein 1B chr22 Not Cancer Driver No 1 intact 174 332 48 48 0
SMG5 SMG5 Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 chr1 Not Cancer Driver No 1 intact 132 295 51 51 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 Not Cancer Driver No 1 intact 36 73 4 4 0
SSB SSB P05455 Lupus La protein chr2 Not Cancer Driver No 1 intact 39 181 18 18 0
SSRP1 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 1 intact 92 308 35 35 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact 10 76 7 7 0
TLN1 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 intact 278 1109 126 126 0
TMA7 TMA7 Q9Y2S6 Translation machinery-associated protein 7 chr3 Not Cancer Driver No 1 intact 3 64 3 3 0
TMC1 TMC1 Q8TDI8 Transmembrane channel-like protein 1 chr9 Not Cancer Driver No 1 intact 121 97 10 10 2
TMEM196 TMEM196 Q5HYL7 Transmembrane protein 196 chr7 Not Cancer Driver No 1 intact 36 12 1 1 0
TOGARAM1_ENST00000361577 TOGARAM1 Q9Y4F4 TOG array regulator of axonemal microtubules protein 1 chr14 Not Cancer Driver No 1 intact 230 703 101 101 3
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 intact 35 230 27 27 21
TPPP3_ENST00000393957 TPPP3 Q9BW30 Tubulin polymerization-promoting protein family member 3 chr16 Not Cancer Driver No 1 intact 21 63 10 10 0
TTF1 TTF1 Q15361 Transcription termination factor 1 chr9 Not Cancer Driver No 1 intact 105 535 59 59 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 Not Cancer Driver No 1 intact 7917 12926 2861 2861 10
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 intact 19 45 8 8 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 intact 109 141 24 24 0
VPS26C VPS26C O14972 Vacuolar protein sorting-associated protein 26C chr21 Not Cancer Driver No 1 intact 46 4 0 0 0
VWA5B1 VWA5B1 Q5TIE3 von Willebrand factor A domain-containing protein 5B1 chr1 Not Cancer Driver No 1 intact 63 460 28 28 0
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 1 intact 60 399 27 27 0
YEATS4 YEATS4 O95619 YEATS domain-containing protein 4 chr12 Not Cancer Driver No 1 intact 23 17 1 1 0
ZC3H4 ZC3H4 Q9UPT8 Zinc finger CCCH domain-containing protein 4 chr19 Not Cancer Driver No 1 intact 152 1235 145 145 0
ZCCHC10 ZCCHC10 Q8TBK6 Zinc finger CCHC domain-containing protein 10 chr5 Not Cancer Driver No 1 intact 12 144 11 11 0
ZNF611 ZNF611 Q8N823 Zinc finger protein 611 chr19 Not Cancer Driver No 1 intact 139 178 40 40 0
ZNF695 ZNF695 Q8IW36 Zinc finger protein 695 chr1 Not Cancer Driver No 1 intact 96 16 4 4 0
ZSCAN29 ZSCAN29 Q8IWY8 Zinc finger and SCAN domain-containing protein 29 chr15 Not Cancer Driver No 1 intact 88 489 61 61 0