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FGFR1_ENST00000447712 ,FGFR1 ,P11362
  • Uniprot Accession= P11362
  • Ensembl Transcript= ENST00000447712.6
  • Uniprot Name= FGFR1
  • Name= Fibroblast growth factor receptor 1
  • Chromosome= chr8
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 271
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 270
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABCF2 ABCF2 Q9UG63 ATP-binding cassette sub-family F member 2 chr7 Not Cancer Driver No 1 intact 112 153 20 20 0
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 1 intact 55 360 39 39 0
ABR ABR Q12979 Active breakpoint cluster region-related protein chr17 Not Cancer Driver No 1 intact 122 184 36 36 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 112 43 5 5 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
ADD2_ENST00000407644 ADD2 P35612 Beta-adducin chr2 Not Cancer Driver No 1 intact 157 423 104 104 0
AFAP1_ENST00000358461 AFAP1 Q8N556 Actin filament-associated protein 1 chr4 Not Cancer Driver No 1 hippie 104 487 60 60 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 Not Cancer Driver No 1 hippie 31 297 21 21 0
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 intact 58 108 10 10 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ANK1_ENST00000347528 ANK1 P16157 Ankyrin-1 chr8 Census Yes 1 hippie, biogrid 405 810 171 171 3
ANOS1 ANOS1 P23352 Anosmin-1 chrX Not Cancer Driver No 1 intact, hippie 124 195 44 44 14
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 Not Cancer Driver No 1 hippie, biogrid 75 12 0 0 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 hippie 17 0 0 0 0
ARGLU1 ARGLU1 Q9NWB6 Arginine and glutamate-rich protein 1 chr13 Not Cancer Driver No 1 intact, hippie 37 246 33 33 0
ARMH4 ARMH4 Q86TY3 Armadillo-like helical domain-containing protein 4 chr14 Not Cancer Driver No 1 hippie 121 671 109 109 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 intact, hippie 19 9 2 2 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 Not Cancer Driver No 1 hippie, biogrid 83 51 5 5 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 17 112 9 9 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 Census Yes 1 hippie 30 39 2 2 0
BCAN BCAN Q96GW7 Brevican core protein chr1 Not Cancer Driver No 1 hippie, biogrid 198 341 75 75 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 Not Cancer Driver No 1 hippie 28 144 18 18 0
C1QTNF9B C1QTNF9B B2RNN3 Complement C1q and tumor necrosis factor-related protein 9B chr13 Not Cancer Driver No 1 hippie, biogrid 62 183 43 43 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 2 intact, hippie 65 334 38 38 0
CD44 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 3 hippie, biogrid 75 542 60 60 0
CD79B_ENST00000006750 CD79B P40259 B-cell antigen receptor complex-associated protein beta chain chr17 Census, Compendium Yes 1 hippie, biogrid 25 43 10 10 1
CD83 CD83 Q01151 CD83 antigen chr6 Not Cancer Driver No 1 hippie, biogrid 24 48 8 8 0
CD8B_ENST00000390655 CD8B P10966 T-cell surface glycoprotein CD8 beta chain chr2 Not Cancer Driver No 1 hippie, biogrid 37 10 0 0 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 44 198 15 15 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 3 intact, hippie 52 214 31 31 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDH11 CDH11 P55287 Cadherin-11 chr16 Census, Compendium Yes 1 hippie 264 399 127 127 0
CDH16 CDH16 O75309 Cadherin-16 chr16 Not Cancer Driver No 1 hippie, biogrid 138 373 65 65 0
CDH2 CDH2 P19022 Cadherin-2 chr18 Not Cancer Driver No 1 hippie 238 461 130 130 7
CDHR4 CDHR4 A6H8M9 Cadherin-related family member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 54 111 4 4 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 40 1 0 0 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 intact, hippie 50 34 2 2 0
CEACAM21 CEACAM21 Q3KPI0 Carcinoembryonic antigen-related cell adhesion molecule 21 chr19 Not Cancer Driver No 1 hippie, biogrid 51 73 14 14 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 intact, hippie 21 4 0 0 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 Not Cancer Driver No 1 hippie, biogrid 35 22 4 4 0
CLPTM1 CLPTM1 O96005 Cleft lip and palate transmembrane protein 1 chr19 Not Cancer Driver No 1 hippie 83 163 19 19 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 2 intact, hippie 163 157 18 18 4
CORO1B CORO1B Q9BR76 Coronin-1B chr11 Not Cancer Driver No 1 intact, hippie 41 138 10 10 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 intact, hippie 61 84 13 13 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 2 intact, hippie 412 1796 247 247 33
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie 38 160 25 25 0
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX Census Yes 1 hippie, biogrid 54 62 3 3 0
CSNK1G2 CSNK1G2 P78368 Casein kinase I isoform gamma-2 chr19 Not Cancer Driver No 1 hippie, biogrid 43 111 13 13 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX Not Cancer Driver No 1 hippie 57 65 9 9 0
CTSG CTSG P08311 Cathepsin G chr14 Not Cancer Driver No 1 hippie, biogrid 65 80 29 29 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie 34 13 3 3 1
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DEFB135 DEFB135 Q30KP9 Beta-defensin 135 chr8 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 Not Cancer Driver No 1 hippie 28 37 2 2 0
DLK1 DLK1 P80370 Protein delta homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie 35 196 26 26 0
DNAJC13 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 hippie 276 141 17 17 0
EPB41L4A_ENST00000621003 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 Not Cancer Driver No 1 hippie, biogrid 119 378 65 65 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 hippie 182 140 24 24 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie 298 396 70 70 3
EVI2A_ENST00000461237 EVI2A P22794 Protein EVI2A chr17 Not Cancer Driver No 2 hippie, biogrid 31 131 22 22 0
FAM8A1 FAM8A1 Q9UBU6 Protein FAM8A1 chr6 Not Cancer Driver No 2 hippie, biogrid 34 196 14 14 0
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 Not Cancer Driver No 1 intact, hippie 71 0 0 0 8
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FCGRT_ENST00000426395 FCGRT P55899 IgG receptor FcRn large subunit p51 chr19 Not Cancer Driver No 2 hippie, biogrid 54 65 12 12 0
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 1 hippie 66 0 0 0 1
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 Not Cancer Driver No 1 hippie 56 34 11 11 2
FGF17 FGF17 O60258 Fibroblast growth factor 17 chr8 Not Cancer Driver No 1 hippie 30 107 16 16 3
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 Not Cancer Driver No 1 hippie 40 57 14 14 0
FGF19 FGF19 O95750 Fibroblast growth factor 19 chr11 Not Cancer Driver No 1 intact, hippie 20 36 7 7 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 30 29 2 2 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 Not Cancer Driver No 3 intact, hippie 84 97 51 51 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 Not Cancer Driver No 2 intact, hippie 18 183 5 5 0
FGF3 FGF3 P11487 Fibroblast growth factor 3 chr11 Not Cancer Driver No 1 hippie 40 104 24 24 2
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 Not Cancer Driver No 2 intact, hippie 16 21 3 3 0
FGF5 FGF5 P12034 Fibroblast growth factor 5 chr4 Not Cancer Driver No 1 hippie 64 129 30 30 1
FGF6 FGF6 P10767 Fibroblast growth factor 6 chr12 Not Cancer Driver No 2 intact, hippie 65 0 0 0 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 Not Cancer Driver No 1 hippie 38 22 4 4 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 Not Cancer Driver No 3 intact, hippie 30 79 9 9 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 Not Cancer Driver No 1 hippie 41 43 10 10 1
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 3 intact, hippie 152 230 43 43 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 3 intact, hippie, biogrid 238 228 44 44 72
FLRT1 FLRT1 Q9NZU1 Leucine-rich repeat transmembrane protein FLRT1 chr11 Not Cancer Driver No 2 hippie, biogrid 74 90 9 9 0
FLRT3_ENST00000341420 FLRT3 Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 chr20 Not Cancer Driver No 1 hippie 108 112 15 15 4
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 3 intact, hippie 69 415 58 58 0
FRS3_ENST00000259748 FRS3 O43559 Fibroblast growth factor receptor substrate 3 chr6 Not Cancer Driver No 1 hippie 77 388 58 58 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie 79 570 68 68 1
GAD1 GAD1 Q99259 Glutamate decarboxylase 1 chr2 Not Cancer Driver No 2 hippie, biogrid 113 55 5 5 1
GINM1 GINM1 Q9NU53 Glycoprotein integral membrane protein 1 chr6 Not Cancer Driver No 3 hippie, biogrid 37 39 5 5 0
GJA8 GJA8 P48165 Gap junction alpha-8 protein chr1 Not Cancer Driver No 1 hippie, biogrid 139 173 56 56 9
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 1 hippie 52 11 3 3 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 1 hippie 45 24 2 2 16
GOLGA7B GOLGA7B Q2TAP0 Golgin subfamily A member 7B chr10 Not Cancer Driver No 3 hippie, biogrid 22 24 0 0 0
GRB14 GRB14 Q14449 Growth factor receptor-bound protein 14 chr2 Not Cancer Driver No 1 hippie 83 117 11 11 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 2 intact, hippie 28 10 1 1 0
GREM2 GREM2 Q9H772 Gremlin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 54 22 9 9 3
HEPACAM2_ENST00000394468 HEPACAM2 A8MVW5 HEPACAM family member 2 chr7 Not Cancer Driver No 1 hippie, biogrid 115 50 14 14 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HPX HPX P02790 Hemopexin chr11 Not Cancer Driver No 1 intact, hippie 60 53 8 8 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 intact, hippie 27 15 3 3 11
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 intact, hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie 100 254 43 43 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie 119 141 28 28 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie 93 286 38 38 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 hippie 112 235 27 27 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
HSPG2 HSPG2 P98160 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 Compendium Yes 1 hippie 506 1709 194 194 1
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 Not Cancer Driver No 3 intact, hippie 170 100 49 49 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 Not Cancer Driver No 1 hippie 14 52 7 7 0
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 Compendium Yes 1 hippie, biogrid 55 50 6 6 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 Compendium Yes 2 hippie, biogrid 55 175 22 22 10
IL17RD IL17RD Q8NFM7 Interleukin-17 receptor D chr3 Not Cancer Driver No 1 hippie 98 177 17 17 7
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 Not Cancer Driver No 2 hippie, biogrid 40 0 0 0 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 Not Cancer Driver No 1 hippie, biogrid 91 167 23 23 0
IL32 IL32 P24001 Interleukin-32 chr16 Not Cancer Driver No 1 hippie, biogrid 41 70 17 17 0
IL3RA IL3RA P26951 Interleukin-3 receptor subunit alpha chrX Not Cancer Driver No 1 hippie, biogrid 89 9 2 2 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 124 66 5 5 30
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 hippie 139 43 10 10 1
IZUMO1 IZUMO1 Q8IYV9 Izumo sperm-egg fusion protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 52 56 6 6 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
KCNC3 KCNC3 Q14003 Potassium voltage-gated channel subfamily C member 3 chr19 Not Cancer Driver No 1 hippie, biogrid 76 405 29 29 4
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KCTD5 KCTD5 Q9NXV2 BTB/POZ domain-containing protein KCTD5 chr16 Not Cancer Driver No 1 intact, hippie 22 32 3 3 0
KLB KLB Q86Z14 Beta-klotho chr4 Not Cancer Driver No 1 intact, hippie 139 6 1 1 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 1 hippie 92 94 11 11 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX Not Cancer Driver No 1 hippie 228 442 75 75 54
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 40 9 0 0 0
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 Not Cancer Driver No 1 hippie, biogrid 66 191 39 39 0
LGALS8_ENST00000366584 LGALS8 O00214 Galectin-8 chr1 Not Cancer Driver No 1 hippie, biogrid 43 31 6 6 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LITAF_ENST00000570904 LITAF Q99732 Lipopolysaccharide-induced tumor necrosis factor-alpha factor chr16 Not Cancer Driver No 2 hippie, biogrid 21 67 6 6 5
LLCFC1 LLCFC1 Q96L11-3 Isoform 3 of Sperm-egg fusion protein LLCFC1 chr7 Not Cancer Driver No 1 hippie 42 62 17 17 0
LMAN2 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie 53 36 8 8 0
LRRN2_ENST00000367177 LRRN2 O75325 Leucine-rich repeat neuronal protein 2 chr1 Not Cancer Driver No 2 hippie, biogrid 132 84 18 18 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 44 200 21 21 0
MANSC1 MANSC1 Q9H8J5 MANSC domain-containing protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 53 206 21 21 0
MELTF MELTF P08582 Melanotransferrin chr3 Not Cancer Driver No 1 hippie 106 23 6 6 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 Not Cancer Driver No 1 intact, hippie 95 98 9 9 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 Not Cancer Driver No 1 hippie, biogrid 53 35 7 7 15
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 Not Cancer Driver No 1 hippie 123 29 6 6 2
MREG MREG Q8N565 Melanoregulin chr2 Not Cancer Driver No 2 hippie, biogrid 21 24 2 2 0
MRPS14 MRPS14 O60783 28S ribosomal protein S14, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 26 4 1 1 1
MRPS2 MRPS2 Q9Y399 28S ribosomal protein S2, mitochondrial chr9 Not Cancer Driver No 1 intact, hippie 32 57 6 6 3
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie 18 102 6 6 0
MRPS31 MRPS31 Q92665 28S ribosomal protein S31, mitochondrial chr13 Not Cancer Driver No 1 hippie 46 231 28 28 0
MRPS33 MRPS33 Q9Y291 28S ribosomal protein S33, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 11 37 8 8 0
MRPS6 MRPS6 P82932 28S ribosomal protein S6, mitochondrial chr21 Not Cancer Driver No 1 intact, hippie 17 13 1 1 0
MRPS7 MRPS7 Q9Y2R9 28S ribosomal protein S7, mitochondrial chr17 Not Cancer Driver No 1 hippie 31 26 0 0 1
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie 31 102 2 2 0
NCAM1_ENST00000316851 NCAM1 P13591 Neural cell adhesion molecule 1 chr11 Not Cancer Driver No 1 hippie 207 290 70 70 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 2 intact, hippie 48 111 17 17 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 1 hippie 89 88 19 19 0
NECTIN1 NECTIN1 Q15223 Nectin-1 chr11 Not Cancer Driver No 1 hippie 84 217 36 36 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie 146 211 31 31 0
NRSN1 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 46 17 9 9 0
NUFIP2 NUFIP2 Q7Z417 Nuclear fragile X mental retardation-interacting protein 2 chr17 Not Cancer Driver No 1 intact, hippie 67 623 62 62 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 Not Cancer Driver No 1 intact, hippie 1208 2623 368 368 0
OPCML OPCML Q14982 Opioid-binding protein/cell adhesion molecule chr11 Not Cancer Driver No 1 hippie 125 36 18 18 1
OR1M1_ENST00000429566 OR1M1 Q8NGA1 Olfactory receptor 1M1 chr19 Not Cancer Driver No 1 hippie, biogrid 88 2 0 0 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 intact, hippie 61 79 15 15 1
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 2 intact, hippie 200 1144 170 170 2
PCDHA8 PCDHA8 Q9Y5H6 Protocadherin alpha-8 chr5 Not Cancer Driver No 1 hippie, biogrid 344 273 73 73 0
PCDHB7 PCDHB7 Q9Y5E2 Protocadherin beta-7 chr5 Not Cancer Driver No 1 hippie, biogrid 354 128 58 58 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 52 50 10 10 0
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 Not Cancer Driver No 1 hippie 64 96 9 9 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 Not Cancer Driver No 1 intact, hippie 38 67 10 10 0
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 Not Cancer Driver No 1 hippie 65 97 19 19 0
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 30 74 16 16 0
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 Not Cancer Driver No 1 hippie 51 38 4 4 8
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 4 intact, hippie 154 268 61 61 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 2 intact, hippie 96 418 47 47 3
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact, hippie 677 2130 272 272 2
POLRMT POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 188 253 31 31 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie 65 243 31 31 0
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 hippie 72 17 1 1 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 2 intact, hippie 49 140 25 25 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 2 intact, hippie 129 260 38 38 60
PTPRN2 PTPRN2 Q92932 Receptor-type tyrosine-protein phosphatase N2 chr7 Not Cancer Driver No 1 hippie, biogrid 274 580 169 169 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 Not Cancer Driver No 1 hippie 26 39 3 3 2
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 hippie 20 41 4 4 0
RAB15 RAB15 P59190 Ras-related protein Rab-15 chr14 Not Cancer Driver No 1 hippie 18 50 5 5 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie 16 38 2 2 0
RAB2B RAB2B Q8WUD1 Ras-related protein Rab-2B chr14 Not Cancer Driver No 1 hippie 18 48 4 4 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie 32 65 15 15 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie 27 11 0 0 4
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 hippie 37 26 3 3 0
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie 18 21 1 1 0
RAET1E RAET1E Q8TD07 Retinoic acid early transcript 1E chr6 Not Cancer Driver No 2 hippie, biogrid 40 0 0 0 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 Not Cancer Driver No 1 hippie 27 5 0 0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 1 hippie 70 167 14 14 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie 35 125 11 11 0
RIN1 RIN1 Q13671 Ras and Rab interactor 1 chr11 Not Cancer Driver No 1 hippie 76 376 43 43 0
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 hippie, biogrid 41 102 10 10 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 Census, Compendium Yes 1 intact, hippie 26 15 1 1 0
RPL22L1 RPL22L1 Q6P5R6 60S ribosomal protein L22-like 1 chr3 Not Cancer Driver No 1 intact, hippie 16 22 4 4 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie 50 69 3 3 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 2 intact, hippie 94 178 32 32 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 133 91 15 15 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX Compendium Yes 3 hippie, biogrid 106 145 18 18 13
RTN1 RTN1 Q16799 Reticulon-1 chr14 Not Cancer Driver No 1 hippie 177 573 134 134 0
RTN3 RTN3 O95197 Reticulon-3 chr11 Not Cancer Driver No 1 hippie 132 707 87 87 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 hippie 62 100 13 13 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 Compendium Yes 1 hippie 90 184 26 26 0
S100B S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie 17 13 1 1 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 hippie, biogrid 63 16 5 5 3
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 1 hippie, biogrid 21 19 2 2 5
SH3BP2_ENST00000435136 SH3BP2 P78314 SH3 domain-binding protein 2 chr4 Not Cancer Driver No 1 hippie 71 356 43 43 7
SHB SHB Q15464 SH2 domain-containing adapter protein B chr9 Not Cancer Driver No 1 hippie 56 334 36 36 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SHE SHE Q5VZ18 SH2 domain-containing adapter protein E chr1 Not Cancer Driver No 1 hippie 65 405 52 52 0
SLA_ENST00000338087 SLA Q13239 Src-like-adapter chr8 Not Cancer Driver No 1 hippie 59 51 11 11 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 Not Cancer Driver No 2 hippie, biogrid 69 17 4 4 1
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 hippie 41 0 0 0 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie 127 258 48 48 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 Compendium Yes 2 intact, hippie 197 458 62 62 38
SPATS2L_ENST00000409140 SPATS2L Q9NUQ6 SPATS2-like protein chr2 Not Cancer Driver No 1 intact, hippie 69 428 53 53 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SRP19 SRP19 P09132 Signal recognition particle 19 kDa protein chr5 Not Cancer Driver No 1 intact, hippie 17 49 7 7 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 Not Cancer Driver No 1 hippie 40 117 9 9 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 1 hippie 21 156 9 9 0
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 73 141 24 24 3
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 Not Cancer Driver No 1 intact, hippie 68 115 13 13 0
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 Not Cancer Driver No 1 hippie, biogrid 47 17 4 4 1
TEX45 TEX45 Q8NA69 Testis-expressed protein 45 chr19 Not Cancer Driver No 1 hippie 41 415 30 30 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 3 hippie, biogrid 106 60 16 16 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 Not Cancer Driver No 1 hippie 129 268 41 41 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 Not Cancer Driver No 1 hippie 61 149 21 21 38
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie 16 22 2 2 0
TMEM109 TMEM109 Q9BVC6 Transmembrane protein 109 chr11 Not Cancer Driver No 1 hippie 39 7 0 0 0
TMEM30B TMEM30B Q3MIR4 Cell cycle control protein 50B chr14 Not Cancer Driver No 2 hippie, biogrid 18 17 0 0 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 Not Cancer Driver No 1 hippie, biogrid 39 26 3 3 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 1 intact, hippie 40 190 24 24 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 Not Cancer Driver No 3 hippie, biogrid 44 190 19 19 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 1 hippie 137 593 81 81 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 132 799 63 63 0
TPCN2 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 73 16 0 0 0
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 Not Cancer Driver No 1 intact, hippie 56 59 10 10 2
TSHR TSHR P16473 Thyrotropin receptor chr14 Census Yes 1 hippie, biogrid 128 38 9 9 39
TSPAN3 TSPAN3 O60637 Tetraspanin-3 chr15 Not Cancer Driver No 3 hippie, biogrid 23 0 0 0 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie 41 52 9 9 0
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie 73 39 4 4 5
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 hippie 91 61 16 16 2
UGT1A7 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 Not Cancer Driver No 1 hippie, biogrid 110 11 2 2 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 hippie 165 113 19 19 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie 38 36 4 4 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie 35 9 1 1 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0
ZDHHC11 ZDHHC11 Q9H8X9 Palmitoyltransferase ZDHHC11 chr5 Not Cancer Driver No 2 hippie, biogrid 68 76 24 24 0
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 Census Yes 1 hippie 144 583 68 68 0